Ethicon Wound Closure Portfolio

Designed to Optimize Patient

Comfort and Healing in
Episiotomy, Natural Tearing,
and Cesarean Section
Whether your patient delivers vaginally or via Cesarean section,
Ethicon’s portfolio of wound closure products provides excellent
comfort, strength, and protection at every layer of closure.
 Episiotomy and
Natural Tearing
Over 85% of women sustain some
form of perineal trauma after vaginal
birth, which can lead to significant
pain, discomfort, and physical and
emotional challenges during the
early postnatal period.1

VICRYL RAPIDE™ (polyglactin 910) Suture

Ethicon’s fastest absorbing synthetic suture for superior patient comfort2,3

Significant reduction Significant reduction Significant reduction Significant reduction

in uncomfortable stitches in perineal pain in analgesic use in dyspareunia
and analgesic use compared to chromic catgut2 compared to standard compared to both chromic catgut
compared to chromic catgut 2 polyglactin 910 suture3 and standard polyglactin 9103

24-48 hours 3-5 days 10 days 6 weeks

postpartum postpartum postpartum postpartum

Significant reduction VICRYL RAPIDE Wound healing

in wound indurations, Suture falls off as significantly
wound dehiscence the wound heals increased
and wound discharge at 7-10 days4 compared to chromic catgut2
compared to chromic catgut2

Faster absorption for optimized healing

Reduced need for suture removal compared
to standard polyglactin 910 suture3

The third-party trademarks used herein are trademarks of their respective owner.
 C-section
Ethicon is committed
to providing wound
closure devices that
promote ease of use
as well as optimizing
healing at every
tissue layer—to
better support future
pregnancies and
repeat C-sections.

STRATAFIX™ Knotless Tissue Control Devices

Differentiated technologies to meet surgeon needs by tissue layer

• Significantly less blood loss in C-section5
• More wound-holding security than interrupted suturing,
without knot-related complications6-14
• With significantly more points of fixation than traditional sutures,
STRATAFIX Knotless Tissue Control Devices make it easier to
manage tension on every pass; appropriate tension leads to better
wound healing, a prerequisite for good cosmesis15-17

Addresses known risk factor for surgical site infection (SSI)

• The only commercially available barbed sutures with Plus Antibacterial Technology—for antibacterial protection at every
layer of closure
• Triclosan-coated sutures are now supported by the Centers for Disease Control and Prevention (CDC), the World Health
Organization (WHO), and American College of Surgeons & Surgical Infection Society (ACS & SIS) in new guidelines to
reduce SSIs18-20*
*The CDC, WHO, and ACS & SIS guidelines for reducing the risk of surgical site infections are general to triclosan-coated sutures and are not specific to any one brand.

DERMABOND® PRINEO® Skin Closure System

Strong, protective closure with the cosmesis patients expect

• Significantly greater skin-holding strength than skin staples or
subcuticular suture21†
• Better cosmesis and greater overall patient satisfaction compared
to staples22‡
• No postsurgical dressings may mean easier self-care
and greater self-confidence for patients23

Addresses a known risk factor associated with SSIs

• Provides a flexible microbial-barrier protection 99% effective in vitro
for 72 hours against organisms commonly associated with SSI24§

†In an ex vivo study, more load in N was required to create a 3 +/- 1mm gap between skin edges approximated with DERMABOND PRINEO System (22 cm) than with subcuticular 4-0 MONOCRYL. (poliglecaprone 25)
Suture or PROXIMATE. Ethicon Endo-Surgery skin staples (P=0.00).
‡Double-blinded quantitative research study comparing surgeon experience with DERMABOND PRINEO System (22 cm) and skin staples in total knee arthroplasty. N=83 Orthopaedic surgeons. 90% CI. Fielded June/July 2017.
§Staphylococcus epidermidis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecium.
Product Codes
Episiotomy and Natural Tearing
Perineum

Length Length
Polymer Needle 4-0 3-0 2-0 0 1 Color
(in) (mm)

CT-1, CP-1 36.4 mm 1/2 Circle

VICRYL RAPIDE 5.3 135 VR931 VR932 Undyed
Taperpoint, Reverse Cutting

CT-1, 36.4 mm 1/2 Circle

VICRYL RAPIDE 3.5 90 VR944 VR945 Undyed
Taperpoint

V-34, 36.4 mm 1/2 Circle

VICRYL RAPIDE 3.5 90 VR916 VR917 Undyed
Tapercut

C-section

Uterus

Length Length
Polymer Needle 4-0 3-0 2-0 0 1 Color
(in) (cm)

STRATAFIX
CT-1, 36 mm, 1/2 Circle
Symmetric 18 45 SXPP1A403 SXPP1A401 Dyed
Taper Point
PDS Plus

STRATAFIX CT, 40 mm, 1/2 Circle

Symmetric 18 45 SXPP1A406 Dyed
Taper Point
PDS Plus

STRATAFIX CT-2, 26 mm, 1/2 Circle

Symmetric 18 45 SXPP1A407 Dyed
Taper Point
PDS Plus

STRATAFIX
CTX, 48mm, 1/2 Circle
Spiral 27 70 SXPP1B401 Dyed
Taper Point
PDS Plus

STRATAFIX 6 15 SXPP1B409
CT-1, 36 mm, 1/2 Circle
Spiral 12 30 SXPP1B410 Dyed
Taper Point
PDS Plus 18 45 SXPP1B411

STRATAFIX 12 30 SXMP1B412
CT-1, 36 mm, 1/2 Circle
Spiral MONOCRYL 18 45 SXMP1B413 Undyed
Plus Taper Point
27 70 SXMP1B414

5x5 14 x 14 SXPD2B409
STRATAFIX MH, 36 mm, 1/2 Circle
9x9 24 x 24 SXPD2B410 Dyed
Spiral PDO Taper Point
12 x 12 30 x 30 SXPD2B411

STRATAFIX CT-1, 36 mm, 1/2 Circle

12 x 12 30 x 30 SXPD2B403 Dyed
Spiral PDO Taper Point
Peritoneum

Length Length
Polymer Needle 4-0 3-0 2-0 0 1 Color
(in) (cm)

STRATAFIX Spiral CT-2, 26 mm, 1/2 Circle 6 15 SXMP1B415

Undyed
MONOCRYL Plus Taper Point 12 30 SXMP1B416

STRATAFIX Spiral SH, 26 mm, 1/2 Circle

9 23 SXMP1B427 SXMP1B409 Undyed
MONOCRYL Plus Taper Point

STRATAFIX Spiral CT-1, 36 mm, 1/2 Circle

18 45 SXMP1B429 SXMP1B413 Undyed
MONOCRYL Plus Taper Point

STRATAFIX MH, 36 mm, 1/2 Circle 5x5 14 x 14 SXMD2B400

Spiral PGA-PCL Undyed
Taper Point 14 x 14 36 x 36 SXMD2B401

Fascia

Length Length
Polymer Needle 4-0 3-0 2-0 0 1 Color
(in) (cm)

STRATAFIX
CT-1, 36 mm, 1/2 Circle
Symmetric PDS 18 45 SXPP1A401 SXPP1A404 Dyed
Plus Taper Point 1

STRATFIX
CT, 40 mm, 1/2 Circle
Symmetric PDS 18 45 SXPP1A406 SXPP1A405 Dyed
Taper Point
Plus
1
CTXB, 48 mm, 1/2 Circle
STRATAFIX
Blunt point,
Symmetric PDS 18 45 SXPP1A302 SXPP1A300 Dyed
ETHIGUARD®
Plus
Safety Needle

STRATAFIX
CTX, 48 mm, 1/2 Circle
Symmetric PDS 18 45 SXPP1A402 SXPP1A400 Dyed
Taper Point
Plus

CTB-1, 36 mm, 1/2 Circle

STRATAFIX
Blunt point,
Symmetric PDS 18 45 SXPP1A301 Dyed
ETHIGUARD
Plus
Safety Needle
Subcutaneous

Length Length
Polymer Needle 4-0 3-0 2-0 0 1 Color
(in) (cm)

STRATAFIX
CT-1, 36 mm, 1/2 Circle
Symmetric PDS 18 45 SXPP1A403 Dyed
Plus Taper Point

STRATAFIX 6 15 SXPP1B409
CT-1, 36 mm, 1/2 Circle
Spiral PDS 12 30 SXPP1B410 Dyed
Taper Point
Plus 18 45 SXPP1B411

STRATAFIX
CP-2, 26 mm, 1/2 Circle
Spiral PDS 18 45 SXPP1B403 Dyed
Taper Point
Plus

STRATAFIX
SH, 26 mm, 1/2 Circle
Spiral 9 23 SXMP1B409 Undyed
Taper Point
MONOCRYL Plus

STRATAFIX
CT-1, 36 mm, 1/2 Circle
Spiral 18 45 SXMP1B413 Undyed
Taper Point
MONOCRYL Plus

STRATAFIX RB-1, 17 mm, 1/2 Circle 6 15 SXMP1B424

Spiral Undyed
Taper Point 12 30 SXMP1B425
MONOCRYL Plus

12 30 SXMP1B117 SXMP1B106
STRATAFIX
PS-2, 19 mm, 3/8 Circle 18 45 SXMP1B118 SXMP1B107
Spiral Undyed
Reverse Cutting 24 60 SXMP1B108
MONOCRYL Plus
27 70 SXMP1B119

STRATAFIX 12 30 SXMP1B101
PS-1, 24 mm, 3/8 Circle
Spiral 18 45 SXMP1B102 Undyed
MONOCRYL Plus Reverse Cutting
24 60 SXMP1B103

5x5 14 x 14 SXPD2B407 SXPD2B409

STRATAFIX MH, 36 mm, 1/2 Circle 9x9 24 x 24 SXPD2B408 SXPD2B410
Spiral PDO Dyed
Taper Point 12 x 12 30 x 30 SXPD2B411
14 x 14 36 x 36 SXPD2B412

STRATAFIX MH, 36 mm, 1/2 Circle 5x5 14 x 14 SXMD2B400

Undyed
Spiral PGA-PCL Taper Point 14 x 14 36 x 36 SXMD2B401

STRATAFIX FS-2, 19 mm, 3/8 Circle 5x5 14 x 14 SXMD2B407 SXMD2B406

Undyed
Spiral PGA-PCL Reverse Cutting 12 x 12 30 x 30 SXMD2B409 SXMD2B408

STRATAFIX FS, 26 mm, 3/8 Circle 5x5 14 x 14 SXMD2B411

Undyed
Spiral PGA-PCL Reverse Cutting 12 x 12 30 x 30 SXMD2B413 SXMD2B412

STRATAFIX FS-1, 24 mm, 3/8 Circle

Spiral PGA-PCL 12 x 12 30 x 30 SXMD2B150 SXMD2B410 Undyed
Reverse Cutting

Skin

Length Length
Device Code
(in) (cm)
DERMABOND
PRINEO
CLR222US 8.6 22
Skin Closure
System
For more information, ask your Ethicon Representative
about the Ethicon Wound Closure Portfolio for Obstetrics.

For complete indications, contraindications, warnings, precautions, and adverse reactions,

please reference full package insert.

References: 1. Kettle C, Tohill S. Perineal care. BMJ Clin Evid. 2008;09:1401. 2. Bharathi A, Reddy DB, Kote GS. A prospective randomized comparative study of vicryl rapide versus chromic catgut for episiotomy
repair. J Clin Diagn Res. 2013;7(2):326-330. 3. Frohlich J, Kettle C. Perineal care. BMJ Clin Evid. 2015;2015. pii:1401. 4. VICRYL RAPIDE™ Instructions for Use. Ethicon, Inc. 5. Peleg D, Ahmad RS, Warsof SL, et al. A
randomized clinical trial of knotless barbed suture vs conventional sutures for closure of the uterine incision at cesarean delivery. Am J Obstet Gynecol. 2018;218:343.e1-7. 6. Nonnenmann H. 100326296: Time
Zero Tissue Holding - Competitive Claims Comparisons for STRATAFIX Knotless Tissue Control Devices vs Various Products. 2015. Ethicon, Inc. 7. Overaker D. AST-2012-0331. Tissue gapping under tension of
porcine cadaveric skin incisions closed with Stratafix Spiral in comparison to Monocryl in both interrupted and continuous stitching patterns. Approved on August 24, 2012. Ethicon, Inc. 8. Nawrocki J.
AST-2013-0056 Performance Testing of STRATAFIX Symmetric PDSSize2-0 suture device for Tissue Holding Strength with Multiple Incision Defects to Measure Gapping. April 4, 2013. Ethicon, Inc.
9. Nonnenmann H. PSE 09-0204, project number 11822. Exploratory histological and biomechanical evaluation of DOLFIN following closure of the ventral abdominal wall in a porcine model at 7±1 days. 2009.
Ethicon, Inc. 10. Nawrocki J. Ethicon Performance Evaluation Memo AST-2012-0510. Performance Testing of STRATAFIX Symmetric Size 2-0 suture device for Tissue Holding Strength with an Incision Defect
to Measure Gapping. December 3, 2012. Ethicon, Inc. 11. Vakil JJ, O'Reilly MP, Sutter EG, Mears SC, Belkoff SM, Khanuja HS. Knee arthrotomy repair with a continuous barbed suture: a biomechanical study.
J Arthroplasty. 2011;26(5):710-713. 12. Eickmann T, Quane E. Total knee arthroplasty closure with barbed sutures. J Knee Surg. 2010;23(3):163-167. 13. Levine BR, Ting N, Della Valle CJ. Use of a barbed suture in
the closure of hip and knee arthroplasty wounds. Orthopedics. 2011;34(9):e473-e475. doi: 10.3928/01477447-20110714-35. 14. Einarsson JI, Chavan NR, Suzuki Y, Jonsdottir G, Vellinga TT, Greenberg JA. Use of
bidirectional barbed suture in laparoscopic myomectomy: evaluation of perioperative outcomes, safety, and efficacy. J Minim Invasive Gynecol. 2011;18(1):92-95. 15. Burgess LP, Morin GV, Rand M, Vossoughi
J, Hollinger JO. Wound healing. Relationship of wound closing tension to scar width in rats. Arch Otolaryngol Head Neck Surg. 1990;116(7):798-802. 16. Höer JJ, Junge K, Schachtrupp A, Klinge U,
Schumpelick V. Influence of laparotomy closure technique on collagen synthesis in the incisional region. Hernia. 2002;6(3):93-8. 17. Hoer J, Klinge U, Schachtrupp A, Töns C, Schumpelick V. Influence
of suture technique on laparotomy wound healing: an experimental study in the rat. Langenbecks Arch Surg. 2001;386(3):218-23. 18. Berríos-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for Disease
Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017. JAMA Surg. doi:10.1001/jamasurg.2017.0904. 19. Global guidelines on the prevention of surgical site infection. World
Health Organization website. http://www.who.int/ gpsc/ssi-prevention- guidelines/en/. Accessed February 22, 2018. 20. Ban KA, Minei JP, Laronga C, et al. American College of Surgeons and Surgical
Infection Society: Surgical Site Infection Guidelines, 2016 Update. J Am Coll Surg. 2016;224:5974. 21. Kumar A. AST20140246. Study to compare the tissue holding strength of DERMABOND® PRINEO®
22 cm Skin Closure System (DP22) to conventional wound closure techniques. September 25, 2014. Ethicon, Inc. 22. PRINEO Claims Research Quant Detail. August 16, 2017. Ethicon, Inc. 23. De Cock EF,
Mueller K, Tan R. Changing the surgical wound closure management pathway: time and supplies with PRINEO vs. standard of care for abdominoplasy surgery in Germany. Poster presented at: International
Society for Pharmaocoeconomics and Outcomes Research, 11th Annual European Congress: November 2008; Athens, Greece. 24. Su W. 06TR071 Study Report for in vitro evaluation of microbial barrier properties of
DERMABOND ProTape. 2006. Ethicon, Inc.

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