Pharmacology
MCQ
1. Which of the following drugs is a beta-blocker?
a) Amlodipine
b) Metoprolol
c) Losartan
d) Lisinopril
Answer: b) Metoprolol
2. What is the mechanism of action of aspirin?
a) Inhibition of cyclooxygenase (COX) enzymes
b) Inhibition of angiotensin-converting enzyme (ACE)
c) Blockage of H1 histamine receptors
d) Stimulation of dopamine receptors
Answer: a) Inhibition of cyclooxygenase (COX) enzymes
3. Which of the following drugs is a calcium channel blocker?
a) Atorvastatin
b) Verapamil
c) Propranolol
d) Furosemide
Answer: b) Verapamil
4. Which of the following is a common side effect of ACE inhibitors?
a) Bradycardia
b) Dry cough
c) Constipation
d) Hyperkalemia
Answer: b) Dry cough
5. Which of the following drugs is used to treat tuberculosis?
a) Ceftriaxone
b) Isoniazid
c) Metronidazole
d) Ciprofloxacin
Answer: b) Isoniazid
6. Which of the following drugs is a proton pump inhibitor (PPI)?
a) Ranitidine
b) Omeprazole
c) Sucralfate
d) Metoclopramide
Answer: b) Omeprazole
7. Which class of drugs is commonly used in the treatment of Parkinson’s disease?
a) Beta agonists
b) Dopamine agonists
c) Anticholinergics
d) ACE inhibitors
Answer: b) Dopamine agonists
8. Which of the following antibiotics inhibits bacterial protein synthesis by binding to the 50S
ribosomal subunit?
a) Penicillin
b) Tetracycline
c) Erythromycin
d) Gentamicin
Answer: c) Erythromycin
9. Which of the following medications is used to reverse opioid overdose?
a) Naloxone
b) Diazepam
c) Atenolol
d) Flumazenil
Answer: a) Naloxone
10. Which of the following drugs is classified as a loop diuretic?
a) Hydrochlorothiazide
b) Spironolactone
c) Furosemide
d) Acetazolamide
Answer: c) Furosemide
Here are additional pharmacology multiple-choice questions:
11. Which of the following drugs is an HMG-CoA reductase inhibitor (statin)?
a) Enalapril
b) Atorvastatin
c) Digoxin
d) Clopidogrel
Answer: b) Atorvastatin
12. Which of the following is a side effect of furosemide?
a) Hyperkalemia
b) Hypokalemia
c) Hypertension
d) Bradycardia
Answer: b) Hypokalemia
13. Which drug is most commonly associated with a disulfiram-like reaction when taken with
alcohol?
a) Metronidazole
b) Amoxicillin
c) Ciprofloxacin
d) Clindamycin
Answer: a) Metronidazole
14. Which of the following drugs is used in the management of peptic ulcer disease by forming a
protective barrier?
a) Pantoprazole
b) Sucralfate
c) Cimetidine
d) Esomeprazole
Answer: b) Sucralfate
15. Which of the following antipsychotic drugs is a dopamine receptor antagonist?
a) Haloperidol
b) Sertraline
c) Risperidone
d) Fluoxetine
Answer: a) Haloperidol
16. Which of the following drugs is used as oral anticoagulant
a) Heparin
b) Warfarin
c) Rivaroxaban
d) Aspirin
Answer: b) Warfarin
17. Which of the following drugs is an opioid analgesic?
a) Ibuprofen
b) Morphine
c) Paracetamol
d) Ketorolac
Answer: b) Morphine
18. What is the main mechanism of action of benzodiazepines like diazepam?
a) Blockage of NMDA receptors
b) Stimulation of GABA-A receptors
c) Inhibition of serotonin reuptake
d) Antagonism of alpha-2 adrenergic receptors
Answer: b) Stimulation of GABA-A receptors
19. Which drug is used as a first-line treatment for acute asthma attacks?
a) Albuterol (Salbutamol)
b) Montelukast
c) Theophylline
d) Beclomethasone
Answer: a) Albuterol (Salbutamol)
20. Which of the following is a selective serotonin reuptake inhibitor (SSRI)?
a) Amitriptyline
b) Venlafaxine
c) Fluoxetine
d) Duloxetine
Answer: c) Fluoxetine
21. Which antiepileptic drug works by inhibiting sodium channels?
a) Valproate
b) Phenytoin
c) Levetiracetam
d) Gabapentin
Answer: b) Phenytoin
22. Which of the following medications is commonly used to manage congestive heart failure by
increasing myocardial contractility?
a) Propranolol
b) Digoxin
c) Lisinopril
d) Carvedilol
Answer: b) Digoxin
23. Which class of drugs is used to treat generalized anxiety disorder by increasing serotonin
levels in the brain?
a) Anticholinergics
b) Benzodiazepines
c) Selective serotonin reuptake inhibitors (SSRIs)
d) Beta-blockers
Answer: c) Selective serotonin reuptake inhibitors (SSRIs)
24. Which of the following is a commonly reported side effect of glucocorticoid therapy?
a) Hypoglycemia
b) Osteoporosis
c) Bradycardia
d) Weight loss
Answer: b) Osteoporosis
25. Which of the following is a non-selective beta-blocker?
a) Metoprolol
b) Atenolol
c) Propranolol
d) Nebivolol
Answer: c) Propranolol
26. Which of the following drugs is used to treat hyperthyroidism
a) Levothyroxine
b) Methimazole
c) Propanolol
d) Amiodarone
Answer: b) Methimazole
27. Which of the following drugs is a short acting insulin analog?
a) Regular insulin
b) Lispro
c) Glargine
d) Aspart
Answer: a
28. Which of the following drugs is an alpha-1 adrenergic receptor blocker used for
hypertension?
a) Prazosin
b) Clonidine
c) Metoprolol
d) Amlodipine
Answer: a) Prazosin
29. Which antibiotic inhibits cell wall synthesis
a) Vancomycin
b) Azithromycin
c) Penicillin
d) Ciprofloxacin
Answer: c) Penicillin
30. Which of the following medications is used as an antiarrhythmic drug by blocking potassium
channels?
a) Amiodarone
b) Lidocaine
c) Adenosine
d) Metoprolol
Answer: a) Amiodarone
Here are multiple-choice questions (MCQs) focused on General Pharmacology:
1. Which of the following terms refers to the study of drug absorption, distribution, metabolism,
and excretion?
a) Pharmacodynamics
b) Pharmacokinetics
c) Pharmacogenetics
d) Toxicology
Answer: b) Pharmacokinetics
2. Which of the following refers to the study of the effects of drugs on the body?
a) Pharmacodynamics
b) Pharmacokinetics
c) Therapeutics
d) Pharmacology
Answer: a) Pharmacodynamics
3. Which of the following routes of drug administration bypasses the first-pass metabolism?
a) Oral
b) Intramuscular
c) Sublingual
d) Rectal
Answer: c) Sublingual
4. Which of the following is an example of a prodrug?
a) Morphine
b) Enalapril
c) Paracetamol
d) Diazepam
Answer: b) Enalapril
6. Which of the following routes of administration ensures 100% bioavailability?
a) Oral
b) Intravenous
c) Subcutaneous
d) Inhalation
Answer: b) Intravenous
7. Which of the following is a Phase I reaction in drug metabolism?
a) Glucuronidation
b) Acetylation
c) Oxidation
d) Methylation
Answer: c) Oxidation
8. Which of the following is NOT an example of a drug receptor?
a) G-protein coupled receptor
b) Ion channel
c) Enzyme
d) DNA
Answer: d) DNA
9. Which of the following refers to the time taken for the plasma concentration of a drug to
reduce to half its original value?
a) Bioavailability
b) Volume of distribution
c) Half-life
d) Clearance
Answer: c) Half-life
10. Which of the following is a measure of drug potency?
a) Therapeutic window
b) Effective dose 50 (ED50)
c) Maximum tolerated dose
d) Duration of action
Answer: b) Effective dose 50 (ED50)
11. Which of the following drugs has a high first-pass metabolism?
a) Nitroglycerin
b) Aspirin
c) Insulin
d) Diazepam
Answer: a) Nitroglycerin
9. Which term describes the phenomenon where repeated drug administration leads to
decreased drug effects?
a) Synergism
b) Potentiation
c) Tolerance
d) Addiction
Answer: c) Tolerance
1. Which of the following is a commonly used inhaled anesthetic?
a) Propofol
b) Halothane
c) Midazolam
d) Fentanyl
Answer: b) Halothane
2. Which of the following intravenous anesthetics is known for its rapid onset and short duration
of action, making it suitable for induction of anesthesia?
a) Ketamine
b) Etomidate
c) Propofol
d) Thiopental
Answer: c) Propofol
3. Which of the following anesthetics provides dissociative anesthesia and is associated with
hallucinations during recovery?
a) Propofol
b) Midazolam
c) Ketamine
d) Sevoflurane
Answer: c) Ketamine
4. Which of the following inhaled anesthetics has the fastest onset and recovery due to low
blood solubility?
a) Nitrous oxide
b) Isoflurane
c) Halothane
d) Desflurane
Answer: a) Nitrous oxide
5. Which anesthetic agent is contraindicated in patients with a history of malignant
hyperthermia?
a) Nitrous oxide
b) Sevoflurane
c) Halothane
d) Thiopental
Answer: c) Halothane
1. Which of the following muscle relaxants is a depolarizing neuromuscular blocker?
a) Pancuronium
b) Vecuronium
c) Succinylcholine
d) Atracurium
Answer: c) Succinylcholine
2. Which of the following drugs can be used to reverse the effects of non-depolarizing
neuromuscular blockers like vecuronium?
a) Atropine
b) Neostigmine
c) Dantrolene
d) Fentanyl
Answer: b) Neostigmine
3. Which drug is used to treat malignant hyperthermia, a rare complication of anesthesia and
muscle relaxants?
a) Diazepam
b) Neostigmine
c) Dantrolene
d) Succinylcholine
Answer: c) Dantrolene
4. Which of the following muscle relaxants undergoes spontaneous degradation in plasma
(Hofmann elimination)?
a) Succinylcholine
b) Atracurium
c) Pancuronium
d) Rocuronium
Answer: b) Atracurium
5. Which of the following drugs causes prolonged muscle paralysis in patients with
pseudocholinesterase deficiency?
a) Atracurium
b) Pancuronium
c) Succinylcholine
d) Rocuronium
Answer: c) Succinylcholine
1. Which of the following drugs is an alkylating agent used in chemotherapy?
a) Methotrexate
b) Cyclophosphamide
c) Doxorubicin
d) Paclitaxel
Answer: b) Cyclophosphamide
2. Which of the following chemotherapeutic agents inhibits dihydrofolate reductase (DHFR)?
a) Methotrexate
b) Cisplatin
c) 5-Fluorouracil
d) Vincristine
Answer: a) Methotrexate
3. Which of the following drugs is an antitumor antibiotic known for causing cardiotoxicity?
a) Bleomycin
b) Doxorubicin
c) Cisplatin
d) Vinblastine
Answer: b) Doxorubicin
4. Which of the following drugs is a platinum-based chemotherapeutic agent that causes
nephrotoxicity and ototoxicity?
a) Cisplatin
b) Paclitaxel
c) Methotrexate
d) Etoposide
Answer: a) Cisplatin
5. Which of the following drugs works by stabilizing microtubules, thus preventing cell division?
a) Methotrexate
b) Paclitaxel
c) Vincristine
d) 5-Fluorouracil
Answer: b)
1. Which of the following drugs is a proton pump inhibitor (PPI) used to treat peptic ulcer
disease?
a) Ranitidine
b) Omeprazole
c) Metoclopramide
d) Sucralfate
Answer: b) Omeprazole
2. Which of the following drugs is a 5-HT3 receptor antagonist used to prevent nausea and
vomiting?
a) Ondansetron
b) Loperamide
c) Domperidone
d) Dicyclomine
Answer: a) Ondansetron
3. Which of the following drugs is used as an antidiarrheal by acting on opioid receptors in the
gut?
a) Metoclopramide
b) Loperamide
c) Ranitidine
d) Pantoprazole
Answer: b) Loperamide
4. Which drug is used to form a protective barrier over ulcers in the gastrointestinal tract?
a) Sucralfate
b) Misoprostol
c) Omeprazole
d) Ranitidine
Answer: a) Sucralfate
5. Which of the following drugs is a prostaglandin analog used to prevent NSAID-induced
gastric ulcers?
a) Omeprazole
b) Sucralfate
c) Misoprostol
d) Bismuth subsalicylate
Answer: c) Misoprostol
