Version: 1.

0
Revision date: 04-04-2014

SAFETY DATA SHEET

1. Identification

Product identifier: Cyclohexane

Other means of identification

Product No.: 9438, V552, 9206, 9292, 9258, 4878, 11219

Recommended use and restriction on use

Recommended use: Not available.
Restrictions on use: Not known.

Manufacturer/Importer/Supplier/Distributor information

Manufacturer
Company Name: Avantor Performance Materials, Inc.
Address: 3477 Corporate Parkway, Suite 200
Center Valley, PA 18034
Telephone:
Customer Service: 855-282-6867
Fax:
Contact Person: Environmental Health & Safety
e-mail: info@avantormaterials.com

Emergency telephone number:

24 Hour Emergency: 908-859-2151

Chemtrec: 800-424-9300

2. Hazard(s) identification

Hazard classification
Physical hazards
Flammable liquids Category 2
Health hazards
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2B
Specific target organ toxicity - single Category 3
exposure
Aspiration hazard Category 1
Environmental hazards
Acute hazards to the aquatic Category 2
environment
Chronic hazards to the aquatic Category 2
environment

Label elements

Hazard symbol:

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Signal word: Danger

Hazard statement: Highly flammable liquid and vapor.

Causes skin irritation.
Causes eye irritation.
May be fatal if swallowed and enters airways.
May cause respiratory irritation.
May cause drowsiness or dizziness.
Toxic to aquatic life with long lasting effects.

Precautionary statement

Prevention: Keep away from heat/sparks/open flames/hot surfaces. No smoking. Keep

container tightly closed. Ground/bond container and receiving equipment.
Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-
sparking tools. Take precautionary measures against static discharge. Do
not eat, drink or smoke when using this product. Avoid breathing
dust/fume/gas/mist/vapors/spray. Wear protective gloves/eye
protection/face protection. Use only outdoors or in a well-ventilated area.
Wash hands thoroughly after handling. Avoid release to the environment.

Response: In case of fire: Use water spray, foam, dry powder or carbon dioxide for
extinction. IF SWALLOWED: Immediately call a POISON CENTER or
doctor/physician. Do NOT induce vomiting. IF ON SKIN (or hair):
Remove/take off immediately all contaminated clothing. Rinse skin with
water/shower. If skin irritation occurs: Get medical advice/attention. IF IN
EYES: Rinse cautiously with water for several minutes. Remove contact
lenses, if present and easy to do. Continue rinsing. If eye irritation persists:
Get medical advice/attention. IF INHALED: Remove victim to fresh air and
keep at rest in a position comfortable for breathing. Specific treatment (see
this label). Collect spillage.

Storage: Store in a well-ventilated place. Keep cool. Keep container tightly closed.
Store locked up.

Disposal: Dispose of contents/container to an appropriate treatment and disposal

facility in accordance with applicable laws and regulations, and product
characteristics at time of disposal.

Other hazards which do not Static accumulating flammable liquid can become electrostatically charged
result in GHS classification: even in bonded and grounded equipment. Sparks may ignite liquid and
vapor. May cause flash fire or explosion.

3. Composition/information on ingredients

Substances

Common name CAS

Chemical identity Content in percent (%)*
and synonyms number

CYCLOHEXANE 110-82-7 98 - 100%

* All concentrations are percent by weight unless ingredient is a gas. Gas concentrations are in percent by volume.

4. First-aid measures

General information: Get medical advice/attention if you feel unwell. Show this safety data sheet
to the doctor in attendance.

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Ingestion: Call a physician or poison control center immediately. Do NOT induce

vomiting.

Inhalation: Move to fresh air. Get medical attention if symptoms persist.

Skin contact: Wash with soap and water. If skin irritation occurs: Get medical
advice/attention. Take off immediately all contaminated clothing. Wash
contaminated clothing before reuse.

Eye contact: IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing. If eye irritation
persists: Get medical advice/attention.

Most important symptoms/effects, acute and delayed

Symptoms: Irritating to eyes, respiratory system and skin. Narcotic effect.

Indication of immediate medical attention and special treatment needed

Treatment: Symptoms may be delayed. Treat symptomatically.

5. Fire-fighting measures

General fire hazards: Flammable liquid and vapor.

Suitable (and unsuitable) extinguishing media

Suitable extinguishing Water spray, foam, dry powder or carbon dioxide.

media:

Unsuitable extinguishing Avoid water in straight hose stream; will scatter and spread fire.
media:

Specific hazards arising from Vapors may cause a flash fire or ignite explosively. Vapors may travel
the chemical: considerable distance to a source of ignition and flash back. Prevent
buildup of vapors or gases to explosive concentrations. Heat may cause the
containers to explode.

Special protective equipment and precautions for firefighters

Special fire fighting Use water spray to keep fire-exposed containers cool. Water may be
procedures: ineffective in fighting the fire. Fight fire from a protected location. Move
containers from fire area if you can do so without risk.

Special protective equipment Firefighters must use standard protective equipment including flame
for fire-fighters: retardant coat, helmet with face shield, gloves, rubber boots, and in
enclosed spaces, SCBA.

6. Accidental release measures

Personal precautions, ELIMINATE all ignition sources (no smoking, flares, sparks or flames in
protective equipment and immediate area). Keep unauthorized personnel away. Keep upwind. Use
emergency procedures: personal protective equipment. Do not touch damaged containers or spilled
material unless wearing appropriate protective clothing. Ventilate closed
spaces before entering them. See Section 8 of the MSDS for Personal
Protective Equipment.

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Methods and material for Eliminate all ignition sources if safe to do so. Take precautionary measures
containment and cleaning against static discharges. Stop leak if possible without any risk. Use only
up: non-sparking tools. Absorb spill with vermiculite or other inert material, then
place in a container for chemical waste. Clean surface thoroughly to
remove residual contamination. Dike far ahead of larger spill for later
recovery and disposal.

Notification Procedures: Prevent entry into waterways, sewer, basements or confined areas. Stop
leak if you can do so without risk. Inform authorities if large amounts are
involved.

Environmental precautions: Do not contaminate water sources or sewer. Prevent further leakage or
spillage if safe to do so.

7. Handling and storage

Precautions for safe handling: DO NOT handle, store or open near an open flame, sources of heat or
sources of ignition. Protect material from direct sunlight. Obtain special
instructions before use. Do not handle until all safety precautions have
been read and understood. Take precautionary measures against static
discharges. Ground/bond container and receiving equipment. Use
explosion-proof electrical/ventilating/lighting/equipment. Use only non-
sparking tools. Wear protective gloves/protective clothing/eye
protection/face protection. Avoid contact with eyes, skin, and clothing. Use
only with adequate ventilation. Wash hands thoroughly after handling.

Conditions for safe storage, Keep away from food, drink and animal feeding stuffs. Keep container
including any tightly closed in a cool, well-ventilated place. Ground container and transfer
incompatibilities: equipment to eliminate static electric sparks. Comply with all national, state,
and local codes pertaining to the storage, handling, dispensing, and
disposal of flammable liquids.

8. Exposure controls/personal protection

Control parameters
Occupational exposure limits
Chemical identity Type Exposure Limit values Source

CYCLOHEXANE TWA 100 ppm US. ACGIH Threshold Limit Values (2011)
REL 300 ppm 1,050 mg/m3 US. NIOSH: Pocket Guide to Chemical
Hazards (2010)
PEL 300 ppm 1,050 mg/m3 US. OSHA Table Z-1 Limits for Air
Contaminants (29 CFR 1910.1000) (02 2006)
TWA 300 ppm 1,050 mg/m3 US. OSHA Table Z-1-A (29 CFR 1910.1000)
(1989)
TWA 300 ppm 1,050 mg/m3 US. Tennessee. OELs. Occupational Exposure
Limits, Table Z1A (06 2008)
ST ESL 3,400 µg/m3 US. Texas. Effects Screening Levels (Texas
Commission on Environmental Quality) (12
2010)
AN ESL 340 µg/m3 US. Texas. Effects Screening Levels (Texas
Commission on Environmental Quality) (12
2010)
ST ESL 1,000 ppb US. Texas. Effects Screening Levels (Texas
Commission on Environmental Quality) (12
2010)
AN ESL 100 ppb US. Texas. Effects Screening Levels (Texas
Commission on Environmental Quality) (12
2010)
TWA PEL 300 ppm 1,050 mg/m3 US. California Code of Regulations, Title 8,
Section 5155. Airborne Contaminants (08
2010)

Appropriate engineering No data available.

controls

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Individual protection measures, such as personal protective equipment

General information: Good general ventilation (typically 10 air changes per hour) should be used.
Ventilation rates should be matched to conditions. If applicable, use
process enclosures, local exhaust ventilation, or other engineering controls
to maintain airborne levels below recommended exposure limits. If
exposure limits have not been established, maintain airborne levels to an
acceptable level. An eye wash and safety shower must be available in the
immediate work area. Use explosion-proof ventilation equipment.

Eye/face protection: Wear safety glasses with side shields (or goggles).

Skin protection
Hand protection: Chemical resistant gloves

Other: Wear suitable protective clothing.

Respiratory protection: In case of inadequate ventilation use suitable respirator.

Hygiene measures: Always observe good personal hygiene measures, such as washing after
handling the material and before eating, drinking, and/or smoking. Routinely
wash work clothing and protective equipment to remove contaminants.
Provide eyewash station and safety shower.

9. Physical and chemical properties

Appearance
Physical state: Liquid
Form: Liquid
Color: Colorless
Odor: Mild
Odor threshold: No data available.
pH: No data available.
Melting point/freezing point: 6.47 °C
Initial boiling point and boiling range: 80 °C (101 kPa)
Flash Point: -18 °C (Closed Cup)
Evaporation rate: 2.6 ether=1
Flammability (solid, gas): Class IB Flammable Liquid
Upper/lower limit on flammability or explosive limits
Flammability limit - upper (%): 8.4 %(V)
Flammability limit - lower (%): 1.3 %(V)
Explosive limit - upper (%): No data available.
Explosive limit - lower (%): No data available.
Vapor pressure: 12.9 kPa (25 °C)
Vapor density: 2.98 AIR=1
Relative density: 0.78 (20 °C)
Solubility(ies)
Solubility in water: Insoluble in water
Solubility (other): No data available.
Partition coefficient (n-octanol/water): 3.44
Auto-ignition temperature: 473 °F
Decomposition temperature: No data available.
Viscosity: No data available.

Other information
Molecular weight: 84.18 g/mol (C6H12)
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10. Stability and reactivity

Reactivity: No dangerous reaction known under conditions of normal use.

Chemical stability: Material is stable under normal conditions.

Possibility of hazardous Hazardous polymerization does not occur.

reactions:

Conditions to avoid: Heat, sparks, flames.

Incompatible materials: Strong oxidizing agents.

Hazardous decomposition Thermal decomposition may release oxides of carbon.

products:

11. Toxicological information

Information on likely routes of exposure

Ingestion: May be harmful if swallowed.

Inhalation: May cause irritation to the respiratory system. May cause drowsiness or
dizziness.

Skin contact: Causes skin irritation.

Eye contact: Causes eye irritation.

Information on toxicological effects

Acute toxicity (list all possible routes of exposure)
Oral
Product: LD 50 (Rat): 29,820 mg/kg
LD 50 (Mouse): 1,300 mg/kg

Dermal
Product: No data available.

Inhalation
Product: No data available.

Repeated dose toxicity

Product: No data available.

Skin corrosion/irritation
Product: Causes skin irritation.

Serious eye damage/eye irritation

Product: Causes eye irritation.

Respiratory or skin sensitization

Product: Not a skin sensitizer.

Carcinogenicity
Product: No data available.

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IARC Monographs on the Evaluation of Carcinogenic Risks to Humans:

No carcinogenic components identified

US. National Toxicology Program (NTP) Report on Carcinogens:

No carcinogenic components identified

US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050):

No carcinogenic components identified

Germ cell mutagenicity

In vitro
Product: No mutagenic components identified

In vivo
Product: No mutagenic components identified

Reproductive toxicity
Product: No data available.

Specific target organ toxicity - single exposure

Product: Inhalation - vapor: Narcotic effect., Respiratory tract irritation.

Specific target organ toxicity - repeated exposure

Product: No data available.

Aspiration hazard
Product: May be fatal if swallowed and enters airways.

Other effects: None known.

12. Ecological information

Ecotoxicity:
Acute hazards to the aquatic environment:
Fish
Product: No data available.
Specified substance(s):
CYCLOHEXANE LC 50 (Bluegill (Lepomis macrochirus), 96 h): 24.99 - 44.69 mg/l Mortality
LC 50 (Fathead minnow (Pimephales promelas), 96 h): 3.961 - 5.181 mg/l
Mortality

Aquatic invertebrates
Product: No data available.
Specified substance(s):
CYCLOHEXANE EC 50 (Water flea (Daphnia magna), 96 h): 96 - 175 mg/l Intoxication

Chronic hazards to the aquatic environment:

Fish
Product: No data available.

Aquatic invertebrates
Product: No data available.

Toxicity to Aquatic Plants

Product: No data available.

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Persistence and degradability

Biodegradation
Product: There are no data on the degradability of this product.

BOD/COD ratio
Product: No data available.

Bioaccumulative potential
Bioconcentration factor (BCF)
Product: No data available on bioaccumulation.

Partition coefficient n-octanol / water (log Kow)

Product: Log Kow: 3.44

Mobility in soil: The product is insoluble in water and will spread on the water surface.

Other adverse effects: Toxic to aquatic life with long lasting effects.

13. Disposal considerations

Disposal instructions: Discharge, treatment, or disposal may be subject to national, state, or local
laws. Dispose of contents/container to an appropriate treatment and
disposal facility in accordance with applicable laws and regulations, and
product characteristics at time of disposal.

Contaminated packaging: Since emptied containers retain product residue, follow label warnings even
after container is emptied.

14. Transport information

DOT
UN number: UN 1145
UN proper shipping name: Cyclohexane
Transport hazard class(es)
Class(es): 3
Label(s): 3
Packing group: II
Marine Pollutant: No

IMDG
UN number: UN 1145
UN proper shipping name: CYCLOHEXANE
Transport hazard class(es)
Class(es): 3
Label(s): 3
EmS No.: F-E, S-D
Packing group: II
Marine Pollutant: No

IATA
UN number: UN 1145
Proper Shipping Name: Cyclohexane
Transport hazard class(es):
Class(es): 3
Label(s): 3
Marine Pollutant: No
Packing group: II

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15. Regulatory information

US federal regulations

TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D)

US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050)
None present or none present in regulated quantities.

CERCLA Hazardous Substance List (40 CFR 302.4):

CYCLOHEXANE Reportable quantity: 1000 lbs.

Superfund amendments and reauthorization act of 1986 (SARA)

Hazard categories

X Acute (Immediate) Chronic (Delayed) X Fire Reactive Pressure Generating

SARA 302 Extremely hazardous substance

None present or none present in regulated quantities.

SARA 304 Emergency release notification

Chemical identity RQ
CYCLOHEXANE 1000 lbs.

SARA 311/312 Hazardous chemical

Chemical identity Threshold Planning Quantity
CYCLOHEXANE 500 lbs

SARA 313 (TRI reporting)

Reporting Reporting threshold for
threshold for manufacturing and
Chemical identity other users processing
CYCLOHEXANE 10000 lbs 25000 lbs.

Clean Water Act Section 311 Hazardous Substances (40 CFR 117.3)
CYCLOHEXANE Reportable quantity: 1000 lbs.

Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130):
None present or none present in regulated quantities.

US state regulations

US. California Proposition 65

No ingredient regulated by CA Prop 65 present.

US. New Jersey Worker and Community Right-to-Know Act

CYCLOHEXANE Listed

US. Massachusetts RTK - Substance List

CYCLOHEXANE Listed

US. Pennsylvania RTK - Hazardous Substances

CYCLOHEXANE Listed

US. Rhode Island RTK

CYCLOHEXANE Listed

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Inventory Status:
Australia AICS: On or in compliance with the inventory
Canada DSL Inventory List: On or in compliance with the inventory
EU EINECS List: On or in compliance with the inventory
EU ELINCS List: Not in compliance with the inventory.
Japan (ENCS) List: Not in compliance with the inventory.
EU No Longer Polymers List: Not in compliance with the inventory.
China Inv. Existing Chemical Substances: On or in compliance with the inventory
Korea Existing Chemicals Inv. (KECI): On or in compliance with the inventory
Canada NDSL Inventory: Not in compliance with the inventory.
Philippines PICCS: On or in compliance with the inventory
US TSCA Inventory: On or in compliance with the inventory
New Zealand Inventory of Chemicals: On or in compliance with the inventory
Japan ISHL Listing: On or in compliance with the inventory
Japan Pharmacopoeia Listing: Not in compliance with the inventory.

16.Other information, including date of preparation or last revision

NFPA Hazard ID

3 Flammability
2 0 Health
Reactivity
Special hazard.
Hazard rating: 0 - Minimal; 1 - Slight; 2 - Moderate; 3 - Serious; 4 - Severe

Issue date: 04-04-2014

Revision date: No data available.

Version #: 1.0

Further information: No data available.

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Disclaimer: THE INFORMATION PRESENTED IN THIS MATERIAL SAFETY DATA

SHEET (MSDS/SDS) WAS PREPARED BY TECHNICAL PERSONNEL
BASED ON DATA THAT THEY BELIEVE IN THEIR GOOD FAITH
JUDGMENT IS ACCURATE. HOWEVER, THE INFORMATION PROVIDED
HEREIN IS PROVIDED “AS IS,” AND AVANTOR PERFORMANCE
MATERIALS MAKES AND GIVES NO REPRESENTATIONS OR
WARRANTIES WHATSOEVER, AND EXPRESSLY DISCLAIMS ALL
WARRANTIES REGARDING SUCH INFORMATION AND THE PRODUCT
TO WHICH IT RELATES, WHETHER EXPRESS, IMPLIED, OR
STATUTORY, INCLUDING WITHOUT LIMITATION, WARRANTIES OF
ACCURACY, COMPLETENESS, MERCHANTABILITY, NON-
INFRINGEMENT, PERFORMANCE, SAFETY, SUITABILITY, STABILITY,
AND FITNESS FOR A PARTICULAR PURPOSE, AND ANY WARRANTIES
ARISING FROM COURSE OF DEALING, COURSE OF PERFORMANCE,
OR USAGE OF TRADE. THIS MSDS/SDS IS INTENDED ONLY AS A
GUIDE TO THE APPROPRIATE PRECAUTIONARY HANDLING OF THE
MATERIAL BY A PROPERLY TRAINED PERSON USING THIS PRODUCT,
AND IS NOT INTENDED TO BE COMPREHENSIVE AS TO THE MANNER
AND CONDITIONS OF USE, HANDLING, STORAGE, OR DISPOSAL OF
THE PRODUCT. INDIVIDUALS RECEIVING THIS MSDS/SDS MUST
ALWAYS EXERCISE THEIR OWN INDEPENDENT JUDGMENT IN
DETERMINING THE APPROPRIATENESS OF SUCH ISSUES.
ACCORDINGLY, AVANTOR PERFORMANCE MATERIALS ASSUMES NO
LIABILITY WHATSOEVER FOR THE USE OF OR RELIANCE UPON THIS
INFORMATION. NO SUGGESTIONS FOR USE ARE INTENDED AS, AND
NOTHING HEREIN SHALL BE CONSTRUED AS, A RECOMMENDATION
TO INFRINGE ANY EXISTING PATENTS OR TO VIOLATE ANY FEDERAL,
STATE, LOCAL, OR FOREIGN LAWS. AVANTOR PERFORMANCE
MATERIALS REMINDS YOU THAT IT IS YOUR LEGAL DUTY TO MAKE
ALL INFORMATION IN THIS MSDS/SDS AVAILABLE TO YOUR
EMPLOYEES.

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