DSM-5 OUD Criteria*
A problematic pattern of opioid use leading to clinically significant impairment or distress, as manifested by at
least two of the following, occurring within a 12-month period.
   CHECK ALL THAT APPLY:
 ☐        1. Opioids are often taken in larger amounts or over a longer period of time than was intended.
 ☐        2. There is a persistent desire or unsuccessful efforts to cut down or control opioid use.
 ☐        3. A great deal of time is spent in activities to obtain the opioid, use the opioid, or recover from its effects.
 ☐        4. Craving, or a strong desire or urge to use opioids.
 ☐        5. Recurrent opioid use resulting in a failure to fulfill major role obligations at work, school, or home.
 ☐        6. Continued opioid use despite having persistent or recurrent social or interpersonal problems caused by
             or exacerbated by the effects of opioids.
 ☐        7. Important social, occupational, or recreational activities are given up or reduced because of opioid use.
 ☐        8. Recurrent opioid use in situations in which it is physically hazardous.
 ☐        9. Continued opioid use despite knowledge of having a persistent or recurrent physical or psychological
             problem that’s likely to have been caused or exacerbated by the substance.
 ☐        10. Tolerance, as defined by either of the following:
              a. A need for markedly increased amounts of opioids to achieve intoxication or desired effect
              b. A markedly diminished effect with continued use of the same amount of an opioid
          Note: This criterion is not met for individuals taking opioids solely under appropriate medical supervision.
 ☐        11. Withdrawal, as manifested by either of the following:
              a. The characteristic opioid withdrawal syndrome
              a. The same (or a closely related) substance is taken to relieve or avoid withdrawal symptoms
          Note: This criterion is not met for individuals taking opioids solely under appropriate medical supervision.
          Total number of symptoms: ________
    ☐ Mild = 2–3 symptoms ☐ Moderate = 4–5 symptoms ☐ Severe = 6 or more symptoms
*Criteria from American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition,
Washington, DC, American Psychiatric Association page 541.
February 2022                             © Oregon Pain Guidance © Dr. Anna Lembke                                             13