CURRICULUM VITAE

Dr Benjamin Chun-Yu WONG

王振宇
 2 BCY Wong - 18 August, 2010

GENERAL INFORMATION
1. Personal Details
2. Appointments
3. Medical Education
4. Postgraduate Training
5. Degrees and Qualifications
6. Professional Licenses
7. Prizes and Scholarships
8. Academic Societies
9. Responsibilities in Academic Societies
10. Voluntary Organisations
11. Responsibilities in Voluntary Organisations
12. Responsibilities in Government Organisations
13. Projects for Voluntary Organizations

TEACHING ACTIVITIES
1. Courses Taught/ organized
2. Honorary teaching/ Adviser
3. Undergraduate Teaching
4. Postgraduate Students Supervised
5. Postgraduate Fellows Supervised
6. Postgraduate Junior Faculty Supervised
7. Students Supervised (Clinical)
8. Examiner
9. New Medical Curriculum Development
10. Administration
11. Media and Public Education
12. Public Education Campaign

RESEARCH ACTIVITIES
1. Journal Editorial Board and Reviewer
2. Research Grant
3. Donation
4. Patent
5. Advisor to Biotechnology and Pharmaceutical industry
6. Steering committee in research project
7. Experience in Setting up Research Laboratory
8. Scholarly Activities
9. Invited Lectures
10. Session Chairpersons in Conferences
11. Organizer of Professional Meetings
12. Professional Organisations
13. Publications: Book Chapters, Original Articles, Abstracts and Conference papers
CLINICAL SERVICES AND DEVELOPMENT
 3 BCY Wong - 18 August, 2010

GENERAL INFORMATION
1. PERSONAL DETAILS:

Surname : Wong 王振宇

First name : Chun Yu (Benjamin)
Sex : Male
Age : 45
Date of Birth : Feb 20, 1965
Marital status : Married
Nationality : British (Hong Kong)

Office Address : Room 307, 3/F, Central Building, Pedder Street, Central, Hong Kong
Tel: (852)-2333-8880
Fax: (852)-2215-3388
Email: bcywong@hku.hk

2. APPOINTMENTS
1. Academic appointments:
11.1996- Assistant Professor,
Department of Medicine, University of Hong Kong, Hong Kong.
1.2000-Associate Professor (Lecturer grade),
Department of Medicine, University of Hong Kong, Hong Kong.
4.2002-Associate Professor (Senior Lecturer grade),
Department of Medicine, University of Hong Kong, Hong Kong.
1.2005-Professor
Department of Medicine, University of Hong Kong, Hong Kong.
2.2008-2010 Simon KY Lee Professor in Gastroenterology
Department of Medicine, University of Hong Kong, Hong Kong.
5.2010-Honorary Professor, Department of Medicine, University of Hong Kong, Hong Kong
(pending final appointment).

2. Clinical appointments :
7.1990-6.1998 Medical Officer, Department of Medicine, Queen Mary Hospital, University of
Hong Kong, Hong Kong.
7.1998-12.99 Honorary Senior Medical and Health Officer, Department of Medicine, Queen Mary
Hospital, University of Hong Kong, Hong Kong.
1.2000-5.2010 Honorary Consultant Physician, Department of Medicine, Queen Mary Hospital,
University of Hong Kong, Hong Kong.
2.2008-5.2010 Director, Endoscopy Center, Department of Medicine, Queen Mary Hospital.
2.2010-Honorary Consultant Physician, Hong Kong Sanitorium & Hospital, Hong Kong.

3. Research appointments:
7.95-6.96 Research Fellow,
Division of Gastroenterology and Hepatology, Department of Medicine,
 4 BCY Wong - 18 August, 2010

University of Birmingham, Birmingham , United Kingdom.

1997- Fellow,
Cancer Research Centre, Faculty of Medicine, University of Hong Kong.
1997- Member, Faculty Steering Group on Chinese Medicine,
Faculty of Medicine, University of Hong Kong.
1998- Fellow,
Center of Alimentary Research and Education, University of Hong Kong
1998- Director,
SKY Lee Digestive Disease Laboratory, Queen Mary Hospital, Hong Kong.
1999- Member,
International Research Program on Traditional Chinese and Natural Medicine,
Faculty of Medicine, University of Hong Kong.
1999- Research Director,
Division of Gastroenterology, Department of Medicine, University of Hong Kong.
1999- 2005 Honorary Research Associate,
Institute of Molecular Biology, University of Hong Kong, Hong Kong.

4. International Honorary Appointments

2000- Visiting Associate Professor, Sun Yat-sen University of Medical Sciences,
Guangzhou, PR China.
2002- Honorary Associate Professor, Guangzhou Medical University, Guangzhou, PR
China
2002.5 Visiting Professor, Southern Arizona VA Health Care System and University of
Arizona Health Sciences Center, University of Arizona, Tucson, USA.
2002 Visiting Professor, Shanghai Second Medical University, Shanghai, PR China.
2003.7 Visiting Professor, Columbia University College of Physicians and Surgeons, New
York, USA.
2003 Honorary Professor, First Military Medical University, Guangzhou, PR China
2004 Guest Professor, Beijing University First Hospital, PR China
2004 Honorary Professor, Capital University of Medical Sciences, Beijing Friendship
Hospital, PR China
2006 Visiting Professor, First Affiliated Hospital at Sun Yat-sen University, Guangzhou,
PR China.
2007 Adjunct Professor, Xiamen University, Xiamen, PR China
2007 Guest Professor, HuaZhong University of Science and Technology, PR China
2008 Honorary Professor, The Fourth Military Medical University, Xian, PR China.
2008 Visiting Professor, Shanghai Jiao Tong University School of Medicine, PR China.
2008 Visiting Professor, University of California Los Angeles, USA.
2009 Honorary Professor, Guangdong General Hospital, Guangzhou, PR China
2009 Visiting Professor, Fudan University Zhongshan Hospital, Shanghai, PR China
2009 Visiting Professor, Chinese PLA General Hospital & Chinese PLA Postgraduate
Medical School

3. MEDICAL EDUCATION:
1984-1989 Faculty of Medicine, University of Hong Kong
1989 Hematology and Oncology (Professor Mark Schumann)
Cancer Research Institute, University of California, San Francisco,
 5 BCY Wong - 18 August, 2010

California, U.S.A. (elective term)

1989 Pulmonary and critical care medicine (Professor Thomas A. Raffin)
Stanford University Medical Center, California, U.S.A. (elective term)

4. POSTGRADUATE TRAINING:
7-1989 Intern : Obstetrics and Gynaecology,
Department of Obstetrics and Gynaecology ,
University of Hong Kong, Kwong Wah Hospital.
10-1989 Intern : General Surgery,
Department of Surgery,University of Hong Kong, Kwong Wah hospital.
1-1990 Intern : Internal Medicine ,
University Department of Medicine, Queen Mary Hospital.
7-1990 Resident : Internal Medicine,
University Department of Medicine, Queen Mary Hospital.
7-1993 : Gastroenterology Fellow
University Department of Medicine, Queen Mary Hospital.
7-1995 : Gastroenterology & Hepatology Research Fellow
Department of Medicine, University of Birmingham, United Kingdom.
7-1996 : Gastroenterology Fellow
University Department of Medicine, Queen Mary Hospital.

5. DEGREES AND QUALIFICATIONS:

1989 Bachelor of Medicine and Bachelor of Surgery, University of Hong Kong (MBBS, HK)
(14/12/1989)
1993 Member, Royal College of Physicians, United Kingdom (MRCP, U.K.)(29/11/1993)
1994 Member, Hong Kong College of Physicians (MHKCP)
1997 Fellow, Hon g Kong College of Physicians (FHKCP) (29/4/1997)
1997 Fellow, Hong Kong Academy of Medicine (Medicine)(FHKAM, Medicine)(7/11/1997)
1998 Specialist, Gastroenterology and Hepatology, Hong Kong Medical Council
2000 Doctor of Medicine, University of Hong Kong (MD, HK)
2001 Fellow, American College of Gastroenterology (FACG)
2002 Fellow, Royal College of Physicians and Surgeons, Glasgow (FRCP, Glasgow)
2002 Fellow, Royal College of Physicians, Edinburgh (FRCP, Edin)
2005 Fellow, Royal College of Physicians, London (FRCP, Lond)
2005 Doctor of Philosophy, University of Hong Kong (Ph.D, HK)
2005 Fellow, American College of Physicians (FACP)

6. PROFESSIONAL LICENSES:
1990 Hong Kong Medical Council, Hong Kong.
1990 General Medical Council, United Kingdom.

7. PRIZES & SCHOLARSHIPS :

1989 Wong Ching Yee Scholarship for elective study
1991 Best free paper award :
 6 BCY Wong - 18 August, 2010

Joint Annual Scientific Meeting 1991 of Hong Kong College of Physicians and
Hong Kong College of Paediatricians
1995 Croucher Foundation Medical Fellowship for one year.
1995 Young Investigator Award :
Third International Conference of Gastroenterology, Hong Kong & Shanghai.
1999 Young Investigator Award for Best Oral Presentation:
Medical Research Conference. Hong Kong.
2001 Outstanding Young Researcher Award, The University of Hong Kong.
2005 Distinguished Poster Award, Asian Pacific Digestive Week, Sept. 25-28, 2005, Seoul,
Korea. Zou B, Lin MCM, Lam SK, Tu SP, Zeng H, Yang Y, Wang JD, He H, Jiang SH,
Kung HF, Wong BCY. Hypermethylation status around exon 1 of XIAP-Associated
Factor 1(XAF1) in human gastric and colon cancer cell line.
2005 Distinguished Poster Award, Asian Pacific Digestive Week, Sept. 25-28, 2005, Seoul,
Korea. Zou B, Chim JCS, Lin MCM, Zeng H, He H, Yu LF, Sun YW, Jiang SH, Wong
BCY. Correlation between the single-site CpG mutation within the gene promoter and
the expression silencing of XIAP -Associated Factor 1 (XAF1) in human colon cancer
cell lines.
2005 Outstanding Researcher Award, The University of Hong Kong
2008 First Class Award, State Scientific and Technological Progress Award, PR China. [The top
national award given to scientists in PR China].
2009 Sir David Todd Lectureship, Hong Kong College of Physician

8. ACADEMIC SOCIETIES:
1989- Hong Kong Medical Association
1994- Hong Kong College of Physicians
1991- Hong Kong Society of Gastroenterology
1991- Hong Kong Association for the Study of Liver Disease
1996- American Association For Cancer Research
1997- International Gastric Cancer Association
1997- Fellow, Cancer Research Center, University of Hong Kong.
1997- American Gastroenterological Association
1997- Fellow, Hong Kong College of Physicians
1997- Fellow, Hong Kong Academy of Medicine (Medicine)
1997- Member, American College of Gastroenterology
1998- Foundation member, Hong Kong Society For Coloproctology
1998- Foundation member, Hong Kong Society of Gastrointestinal Motility
1998- Foundation fellow, Center of Alimentary Research& Education, University of Hong Kong.
1998- Member, Royal College of Physicians, Edinburgh, UK.
1999- Member, Royal College of Physicians, London, UK.
1999- Member, Royal College of Physicians, Glasgow, UK.
2000- Member, American Society of Clinical Oncology, USA.
2000- Member, Center for the Study of Liver Diseases, University of Hong Kong.
2001 Fellow, American College of Gastroenterology (FACG)
2002 Fellow, Royal College of Physicians and Surgeons, Glasgow (FRCP, Glasgow)
2002 Fellow, Royal College of Physicians, Edinburgh (FRCP, Edin)
2003- Member, Functional Brain-Gut Research Group
2005 Fellow, Royal College of Physicians, London (FRCP, Lond)
 7 BCY Wong - 18 August, 2010

2005 Fellow, American College of Physicians (FACP)

2006 Member, American Society for Gastrointestinal Endoscopy (ASGE)

9. RESPONSIBILITIES IN ACADEMIC SOCIETIES

1998- Hon. Secretary, Center of Alimentary Research and Education
1999- Committee Member, OMGE (World Gastroenterology Organisation) working group on
role of Gastroenterologist in management of GI cancer patients.
Chairman – Professor Sidney Winawer, USA
2001- Committee member, International Liaison committee, Asian Pacific Association of
Gastroenterology.
2001- Committee member, OMGE (World Gastroenterology Organisation) subcommittee on
development of digestive cancers.
Chairman – Professor Sidney Winawer, USA
2001- Committte member, OMED (World Organisation of Digestive Endoscopy) Asia Pacific
subcommittee on colorectal cancer screening.
Chairman – Professor Graeme Young, Australia
2001- Committee member, The Federation of Medical Societies of Hong Kong, Hong Kong.
2002- Council Member, Hong Kong Society of Gastroenterology, Hong Kong.
2002- Council Member, Americal Gastroenterological Association, GI oncology section
2003- Committee member, Examination Committee, Hong Kong College of Physicians
2003- Member, Institutional Review Board, University of Hong Kong and Hospital Authority.
2003- Committte member, OMED (World Organisation of Digestive Endoscopy) Screening
Committee
2003- Board of Governors, Journal of Gastroenterology and Hepatology Foundation
2003- Committee member, Practice Parameters Committee, American College of
Gastroenterology, USA
2005- Deputy Chairman, Institutional Review Board, HKU/HA Hong Kong West, 2005-
2005- Committee member, Guidelines and Publications Committee, WGO-OMGE (World
Gastroenterology Organisation) 2005-2009
2005- Committee, International Asian Conference on Cancer Screening.
2008- Vice President, Hong Kong Society of Gastroenterology, Hong Kong.
2008- Board of Directors, International Society of Gastroenterological Carcinogenesis
2008- Editor, Upper GI and Pancreatic Diseases Cochrane Group
2008- Founding council member, Hong Kong IBD Society
2009- Council member, Asian Pacfic Association of Gastroenterology
2010- President, Hong Kong Society of Gastroenterology, Hong Kong.

10. VOLUNTARY OR NON-ACADEMIC ORGANISATIONS

1991- Co-director, Board, Foundation Member of Hong Kong Marrow Match
Foundation Limited
1995- The Hong Kong Liver Foundation
1997- Lions Club of Hong Kong (Host)
1998- The Hong Kong Digestive Foundation
1998- The Society for the Aid and Rehabilitation of Drug Abusers
2003- Shun Tak District Min Yuen Tong of Hong Kong
2004- The Chinese General Chamber of Commerce
2004- The University of Hong Kong Medical Alumni Association
 8 BCY Wong - 18 August, 2010

2005- The Foochow Association Limited, Hong Kong.

2005- Shun Tak Fraternal Association
2006- Worldwide Chinese Investors Association
2007- Federation of Hong Kong Guangdong Community Organisations
2007 Hong Kong Shun Lung Yan Chak Foundation Limited.
2007- Riding for the Disabled Association Limited
2008- Hong Kong Scientist Association
2009- Hong Kong Chinese Medicine Industry Association Ltd
2009- Hong Kong Happy Health Society
2009- Wanchai and Central & Western District Industries and Commerce Association
2009- Hong Kong Liver Foundation

11. RESPONSIBILITIES IN VOLUNTARY ORGANISATIONS

1. Honorary Advisor, The Hong Kong Liver Foundation. 1995-
2. Honorary Treasurer, Lions Club of Hong Kong (Host), 1998
3. First Vice-President, Lions Club of Hong Kong (Host) 2000-2001
4. President, Lions Club of Hong Kong (Host) 2001-2002
5. Board of Directors, Lions Club of Hong Kong (Host) 2001
6. Executive Committee, The S.H. Moore Memorial Fund, The Society for the Aid and
Rehabilitation of Drug Abusers, 1998-
7. Honorary Adviser, The Hong Kong Digestive Foundation, 1998-
8. Council Member, The Hong Kong Digestive Foundation, 2002-
9. Chairman, Research Committee, The Hong Kong Digestive Foundation, 2002-
10. Committee member, Public Education Committee, Hong Kong Digestive Foundation, 2002-
11. Board of Trustees, Lions Club of Hong Kong (Host) Charity Foundation, 2004-
12. Co-opted member, Executive Committee, The University of Hong Kong Medical Alumni
Association , 2004-
13. Medical Consultant, The Foochow Association Limited, 2005-
14. Director, Shun Tak Fraternal Association, 2005-
15. Committee member, The Chinese General Chamber of Commerce, Hong Kong, 2006-
16. Vice Chairman, Eastern District Liaison Sub-committee, The Chinese General Chamber of
Commerce, Hong Kong, 2006-
17. Standing committee, Young Executives’ Sub-committee, The Chinese General Chamber of
Commerce, Hong Kong, 2006-
18. Committee, Member Services Sub-committee, The Chinese General Chamber of Commerce,
Hong Kong, 2006-
19. Committee, Member Liaison Sub-committee, The Chinese General Chamber of Commerce,
Hong Kong, 2006-
20. Director, The Shun Tak District Min Yuen Tong of Hong Kong, 2007-
21. Advisor, Hong Kong Shun Lung Yan Chak Foundation Limited., 2007-
22. Committee, PR and Fund Raising Subcommittee, Riding for the Disabled Association Limited,
2007-
23. Vice Chairman, PR and Fund Raising Subcommittee, Riding for the Disabled Association
Limited, 2008-
24. Chairman, Medical Committee, Shun Tak Fraternal Association, 2008-
25. Council member/ sponsoring body manager, Shuk Tak Fraternity Association Leung Kit Wah
Primary School Management Committee, 2008-
 9 BCY Wong - 18 August, 2010

26. Chairman, International Liaison Subcommittee, Riding for the Disabled Association Limited,
2008-
28. Council member, the Hong Kong Liver Foundation, 2008-
28. Honorary Secretary, Shuk Tak Fraternity Association Leung Kit Wah Primary School
Management Committee, 2008-
29. Vice Chairman, Hong Kong Scientist Association, 2008-
30. Voting Member, Riding for the Disabled Association Limited, 2008-
31. Medical Consultant, Hong Kong Chinese Medicine Industry Association Ltd, 2009-
32. Honorary president, Wanchai and Central & Western District Industries and Commerce
Association, 2009-
33. Council member, Happy Health Society, 2009-
34. Chairman, Steering Committee for Patient Support Groups & Volunteers, the Hong Kong Liver
Foundation, 2009-

12. GOVERNMENT ORGANISATIONS

1. Co-opted member, Environment and Hygiene committee, Southern District Council,
Government of Hong Kong SAR. 2004- Dec 2007
2. Attended the Focus Group meeting organized by Home Affairs Bureau, Aug 2004
3. Attended the Strategy Summit, Council for Sustainable Development, Dec 2004
4. Member, Public Affairs Forum, Government of Hong Kong SAR. 2005- Jun 2008
5. Member, Organizing Committee, 2005/06 Southern District Festival.
6. Member, Advisory Committee on Quality of Water Supplies, Government of HKSAR. 2006-
2011
7. Member, Southern District Arts Festival Organizing Committee. 2006
8. Substantive Member, Human Organ Transplant Board, Government of HKSAR. 2007- 2012
9. Member, 11th Chinese People’s Political Consultative Conference Beijing Committee 2008
10. Member, Southern District Fight Crime Committee. 2008-2011
11. Member, Public Affairs Forum, Government of Hong Kong SAR. 2009-2011
12. Co-opted member, District Development and Environment committee, Southern District
Council, Government of Hong Kong SAR. 2010-2011

13. PROJECTS FOR VOLUNTARY ORGANIZATIONS

1. Riding for the Disabled Association Ltd Hong Kong Charity Ball committee, 2007
2. Chief Editor, RDA Legacy 33. Published by Riding for the Disabled Association Ltd, 2008.
3. Riding for the Disabled Association Ltd Hong Kong Charity Ball committee, 2009
4. Chairman, Organizing committee, 3rd Asia Pacific Conference of Riding for the Disabled
Association Ltd, Hong Kong, 29-30 October, 2009.
5. Riding for the Disabled Association Ltd Hong Kong Charity Ball committee, 2010
 10 BCY Wong - 18 August, 2010

TEACHING ACTIVITIES
1. COURSES TAUGHT/ ORGANIZED
1. Integrated teaching course on peptic ulcer diseases- 1997-
2. Integrated teaching course on jaundice- 1998-
3. Broadening course, University of Hong Kong- Understanding Cancer, 1999-
4. Certificate course for clinic nurses, The Federation of Medical Societies of Hong Kong, 2003.
(Chief organizer)

2. HONARARY TEACHING/ADVISER
1. Health Exhibition 1995, Medical Society, Hong Kong University Student Union.
2. Honarary lecturer- PgD/Msc in Human nutrition/Dietetics- University of Ulster/School of
Professional and Continuing Education, University of Hong Kong. 1997-
3. Honarary lecturer- Post-registration certificate course in endoscopy nursing, 1996-1997
4. Diploma in Gastroenterology Nursing, HKU SPACE, 1999.

3. UNDERGRADUATE TEACHING-
1. MBBS teachings- lectures, bedside teachings.
2. Clerkship coordinator- Introductory clerkship, MBBS. 1997-
3. Examination chief organiser- Medicine year 3 exam, BDS. 1997-
4. Bedside teaching- MBBS, MRCP, BDS courses.
5. Examiner - Medicine year 5 OSCA examination. 1997-
6. Examiner - Medicine year 1 OSCA examination(New curriculum). 1998-
7. Resource staff – BDS II curriculum (New curriculum). 1999-
8. BDS V Assessment Group 2005-6.

4. POSTGRADUATE STUDENTS SUPERVISED

1. Geng Hui ZHU Ph.D. (co-supervisor) 01/01/1995 – 29/7/1998 (completed)
Title: Non-steroidal anti-inflammatory drugs and apoptosis in human
gastric epithelial cell
2. Xiao Ming FAN Ph.D. (principal supervisor) 01/04/1998- 12/2/2001 (completed)
Title: Arachidonic acid metabolism in apoptosis of gastric cancer
3. Xiao Hua JIANG MPhil. (co-supervisor) 09/07/1998 – 31/12/1999
Ph.D. (co-supervisor) 01/01/2000 – 26/7/2002 (completed)
Title: Targeting cell signalling pathway in treatment of gastric
cancer by chemotherapeutic agents
Awarded KP Stephen Cheng Gold Metal for best thesis,
and Li Ka Shing Prize for best thesis.
4. Qing GU Hon RA 10/05/01- 9/2002
MPhil. (principal supervisor) 1/1/2003-1/1/2004
Ph.D. (principal supervisor) 1/1/2004- 23/12/2005 (completed)
Title: Helicobacter pylori and non-steroidal inflammatory drugs in
gastric carcinogenesis
5. Hua HE M Phil (co-supervisor) 01/09/02 – 19/8/2004 (completed)
Title: Molecular mechanisms of anti-carcinogenesis of
nonsteroidal anti-inflammatory drugs and a c-jun-n-terminal
kinase inhibitor in gastrointestinal cancers
 11 BCY Wong - 18 August, 2010

6. Wai Man WONG PhD (principal supervisor) 1/12/2002- 1/6//2004 (completed)

Title: Gastro-oesophageal reflux diseases in Chinese
7. Yuk Kei YEE PhD (principal supervisor) 1/12/2005- 1/6/2007 (completed)
Title: The Journey towards Helicobacter pylori eradication
8. Ting Kin CHEUNG PhD (principal supervisor) 1/12/2005- 6/2008
Title: Gastro-oesophageal reflux disease in Chinese: its
management and impact
9. Lik Wai Benny WONG M.Phil (co-supervisor) 1/2006- 12/2007
PhD (principal supervisor) 12/2007- 10/2009 (completed)
Title: Immune response and signalling mechanisms of Helicobacter
pylori induced gastritis
10. Lui NG PhD (co-supervisor) 1/11/2008-10/2011
11. Siu Chi LAM PhD(co-supervisor) 1/9/2009-

5. POSTGRADUATE FELLOWS SUPERVISED

1. Hong Bo ZHANG M.D. 01/05/1998 - 30/10/1999
From Department of Gastroenterology, Fourth Military Medical
University, Xian, China
2. Rui E FENG M.D. 01/02/1998 – 30/09/2000
From Department of Pathology, Tiantan Hospital, Beijing, China
3. Wei Hong WANG MD, Ph.D. 12/10/1998 – 30/04/2000
4. Wun Chun HUI M.Phil. 10/1998- 29/11/01 (supervisory committee)
5. Ngai Fung SHAM M. Phil 03/1999- 29/11/01 (supervisory committee)
6. Xin Min ZHOU M.D. 10/1999- 10./2000
From Department of Gastroenterology, Fourth Military Medical
University, Xian, China
7. Ping LU M.D. 20/11/99- 11/2000
From Department of Pathology, First Teaching Hospital, Beijing
Medical University, China
8. Wei Ping WANG M.D., Ph.D. 02/01/2000- 30/04/01
9. Tak Ming LI MD 01/04/00- 30/09/00
From Macau
10. Yingjie LIANG Hon RA 14/08/00-13/02/01
From Department of Pathology, Sun Yat Sen Medical University,
Guangzhou, China.
11. Da Dao JING MD 01/02/01-30/07/01
From Department of Gastroenterology, Shanghai First People’s
Hospital, Shanghai, China
12. Yan YIN M.Sc 30/05/00 – 30/05/01
From Institute of Epidemiology and Microbiology, Chinese
Academy of Preventive Medicine, Beijing, China
13. Ting Ting ZHENG MD 9/2000 – 30/6/02
From Medicine, Fujian Hospital, Fujian, China
14. Shao Kai LIN MD 7/2000 – 6/ 2002
15. Shui Ping TU MD 03/01 - 11/2001
PDF 11/2001 – 11/2003
From Gastroenterology, Ruijin Hospital, Shanghai, China
 12 BCY Wong - 18 August, 2010

16. Jing WU MD 01/02/01 – 01/02/02

From Department of Gastroenterology, Fourth Military Medical
University, Xian, China
17. Xing Xiang HE MD 10/2001 – 09/ 2002
From Gastroenterology, Guangzhou Medical University, China
18. Jian Tao CUI Hon RA 26/11/01- 02/2003
From Laboratory of Cancer Molecular Biology, Peking University
School of Oncology, Beijing, China
19. Yi Yang MD 01/11/01 – 16/06/2004
From Gastroenterology, Medical College of Wuhan University,
China

20. Guo Qing LI MD 9/2002 – 15/10/2004

From Department of Gastroenterology, Sun Yat Sen Medical
University, Guangzhou, China
21. Ji De WANG MD 12/2002- 11/2005
Post-doctoral fellow: 8/2007-
From Department of Gastroenterology, First Military Medical
University, Guangzhou, China
22. Bing ZOU MD 12/2002-
From Department of Gastroenterology, Ruijin Hospital, Shanghai.
23. Ge Fan ZHENG MD 1/2003-6/2004
24. Chee Kin HUI MD 3/2003- 09/2003
25. Jun Zhong PENG MD 6/2003-6/2004
From Department of Anatomy, Wuhan Science and Technology
University, Wuhan, China
26. Zehao ZHUANG MD 8/2004- 8/2005
From Department of Gastroenterology, First Affiliated Hospital,
Fujian Medical University, Fujian, China
27. Hua HE MD 9/2004- 6/2006
28. Yun Wei SUN MD 6/2004- 6/2006
From Department of Gastroenterology, Ruijin Hospital, Shanghai.
29. Li Fen YU MD 6/2004- 9/2005
From Department of Gastroenterology, Ruijin Hospital, Shanghai.
30. Sen Lin ZHU MD
From Department of Gastroenterology, Sun Yat Sen Medical
University, Guangzhou, China
31. Yun DAI MD 8/2005-2/2009
From Department of Gastroenterology, Peking University First
Hospital, Beijing, China.
32. Juan MA MD 7/2005-1/2009
From Department of Gastroenterology, Sun Yat Sen Medical
University, Guangzhou, China
33. Qing GU PhD 7/2006- 10/2009
From Beijing University First Hospital, Beijing, China
34. Zesong LI PhD 12/2006- 12/2008
 13 BCY Wong - 18 August, 2010

35. YuSheng ZHANG MD 1/2007- 5/2008

From Southern Medical University, Guangzhou, China
36. Wenjing ZHANG MD 3/2008-9/2010
From Southern Medical University, Guangzhou, China
37. Xueping ZHANG MD 4/2009- 4/ 2010
From Fourth Military Medical University, Xian, China

6. POSTGRADUATE JUNIOR FACULTY SUPERVISED

1. Harry HX XIA MD, PhD.
Reseach Assistant Professor 8/2000-8/2005
Assistant Professor 8/2005-11/2006
2. Shui Ping TU MD, PhD
Post-doctoral fellow, 11/2001-11/2003
3. Jiaqing HUANG MD, PhD
Reseach Assistant Professor 10/2002-9/2004
4. Liang QIAO MD, PhD
Reseach Assistant Professor 2/2005- 6/2009
5. Roberta PANG PhD
Reseach Assistant Professor 6/2007- 10/2011
6. Jide WANG MD, PhD
Post-doctoral fellow, 12/2002-11/2005
Reseach Assistant Professor 8/2007- 9/2010
7. Bing ZOU MD, PhD
Post-doctoral fellow, 12/2007- 5/2010

7. STUDENTS SUPERVISED (CLINICAL)

1. Jason LAM MS 6/97
2. Poch Lor CHIM MS 7/98
3. Ryan CHANG Student attachment program 7/98 - 8/98
4. Gavin LING Student attachment program 7/98 – 8/98
5. Sek Ying CHAIR Clinical Update Program(Nursing) 6/00

8. EXAMINER
1. BDS third year Medicine, examiner since 1997
2. MBBS first formative examination, examiner since 1998
3. MBBS third summative examination, examiner since 2000
4. MBBS second summative examination, examiner since 2000
5. MBBS first summative examination, examiner since 2001
6. MBBS final examination, examiner since 2001
7. MBBS Clinical Competency Test, examiner since 2001.
8. MBBS third formative examination, examiner since 2001.

9. NEW MEDICAL CURRICULUM DEVELOPMENT

1. Tutor workshop training course completion. 1998.
2. MBBS second year, GI system : case writer for one problem-based learning tutorial, 1998-
3. MBBS second year, GI system : Moderator, briefing and de-briefing sessions for problem-based
learning tutorial, 1998-
 14 BCY Wong - 18 August, 2010

4. MBBS second year, GI system : Clinical skills learning and practical session, chief
co-ordinator. 1998-
5. MBBS third year, Integrated Block (Medicine) : Planning, Development, Co-ordinator.
1998-
6. MBBS New clinical curriculum, Year 3-5, (Medicine) : working group, 1998-
7. MBBS New curriculum Clinical skills planning group committee, 2001- 8/2002
8. MBBS Gastrointestinal system block planning group co-ordinator, 2002-
9. MBBS clinical skills and interpersonal skills subcommittee, GI coordinator, 2002-

10. ADMINISTRATION
1. Co-ordinator, Introductory clerkship, MBBS third year teaching. 1997-199
2. Member, Clinical management committee, Department of Medicine, 1998-
3. Director, Simon KY Lee Digestive Disease Center, Department of Medicine, 1998-
4. Physician-in-charge (Administration), Medical Oncology Division, 1997-
5. Co-ordinator, Integrated Block, MBBS third year teaching. 1999-
6. Research Director, Division of Gastroenterology, Department of Medicine, 1999-
7. Member, Committee for selection of outstanding young researcher award 2004, HKU.
8. Member, Working Group on Staff Developoment 2006, HKU.
9. Member, Task force on future development of research postgraduate education, 2007, HKU.
10. Member, Pre-internship program, Undergraduate committee, Dept of Medicine, HKU.2007-
11. Member, Board of Graduate Studies, HKU. Sept 2009 – Aug 2010.
12. Member, RGC Hong Kong PhD Fellowship & University Postgraduate Fellowship Selection
Panel, HKU 2009

11. MEDIA & PUBLIC EDUCATION

1. Spreading infection of Helicobacter pylori. Next magazine. 26 Dec 1997
2. Blood test for gastric cancer. Press conference 13 Jan 1998
3. Liver transplant in Queen Mary Hospital. Sing Tao Daily newspaper. 4 Jan 1998
4. Gastric cancer and Helicobacter pylori. Press conference 23 July 1998
5. Crohn’s diease. Oriental Daily News. 12 Aug 1998
6. Colon cancer. Radio Television Hong Kong radio program. 8 Jan 1999
7. Gastric ulcer and blood group O subjects. Ming Pao Daily newspaper. 17 March 1999.
8. Gastric lavage for drug poisoning. Hong Kong Economy Daily. 16 Jan 1999
9. Constipation. Tin Tin Daily News. 29 March 1999
10. Constipation. Ming Pao Daily News. 29 March 1999
11. High salt and gastric cancer. The Sun newspaper. 30 May 1999
12. Triptolide in gastric cancer treatment. Press conference 24 January 2000, covered by e-media
and press.
13. Colorectal cancer. Sing Tao Daily newspaper. 14 January 2000
14. Younger onset for colon cancer in Hong Kong. 14 February 2000
15. Epigastric pain. Sing Tao Daily newspaper. 6 March 2000
16. Risk of upper endoscopy. Oriental Daily News. 31 March 2000
17. Increased risk of gastric ulcer in blood group O subjects. 10 May 2000
18. Causes of epigastric pain. Ming Pao newspaper. 11 May 2000
19. Three day treatment heals duodenal ulcers. Press conference, covered by e-media and press.
January 2001
20. Three day regime in Helicobacter pylori treatment. Apple Daily newspaper, 13 March 2001.
 15 BCY Wong - 18 August, 2010

21. Management of Helicobacter pylori and peptic ulcer disease. Documentary, ATV, April 2001
22. Increasing antibiotic resistance of Helicobacter pylori in Hong Kong, News program, TVB,
August 2001
23. Press conference, Colon cancer and virtual colonoscopy. Electronic media and press. 9
August 2001.
24. Stomach ulcer bug showing drug resistance, study finds. South China Morning Post. 17 Sept
2001.
25. HK Study on virtual colonoscopy shows promise. Doctor, Key Media International Ltd.
Volume 2:9; page 2.
26. Virtual colonoscopy a new option for cancer screening. Medical Tribune, by Medimedia Asia,
Sept 2001.
27. Virtual technology helps cancer diagnosis. Hi-Tech weekly. 28 August 2001.
28. Abuse of antibiotics. Sun Daily. 2 Sept 2001.
29. Colonic irrigation. Next Magazine 11 October 2001.
30. Peptic ulcer disease and H pylori in Hong Kong. Medical Tribune, by Medimedia Asia,
February 2002.
31. Dyspepsia and Helicobacter pylori in Hong Kong. Medical Tribune, by Medimedia Asia,
March 2002.
32. NSAID therapy in Helicobacter pylori positive patients. Medical Tribune, by Medimedia Asia,
April 2002.
33. Low dose aspirin and NSAIDs in the Helicobacter pylori positive patients. Medical Tribune,
by Medimedia Asia, May 2002.
34. Management of H. pylori infection. Medical Tribune, by Medimedia Asia, June 2002.
35. Peptic ulcer and Helicobacter pylori. Documentary, East Asia Satellite TV Ltd. May 2002
36. Press conference, Recent advances for the prevention of recurrences of ulcer complications
from long term low dose aspirin use. Electronic media and press. 19 July 2002
37. Digestive Diseases, Documentary, in Chinese and Western Medicine, TVB Ltd. 25 July 2002
38. Anti-inflammatory drugs prevent cancer. Ming Pao Daily newspaper. 7 August 2002
39. Gastric cancer and H. pylori- examining the evidence. Medical Tribune, by Medimedia Asia,
Sept 2002.
40. Colorectal cancer in Hong Kong. Hong Kong Economic Times, 11 October, 2002.
41. Upper gastrointestinal diseases, Metro Radio 104, 28 December, 2002
42. Management of Helicobacter pylori infection. Doctor, 2003: 4(2): 8-9.
43. Press conference. GERD in Hong Kong. Electronic media and press. 13 March 2003.
44. New Questionnaire Makes GERD diagnosis Easier. Doctor, 2003; 4(4): 18-20.
45. Digestive Diseases, Documentary, in Importance of Health, TVB Ltd, 11 May, 2003.
46. Questionnaire for digestive diseases, Mingpao daily, 19 May, 2003
47. Digestive Diseases, Documentary, in Doctor and You, RTHK Production, shown on TVB,
21 May, 2003.
48. Aspirin and gastric cancer. Press conference, 3 December, 2003. Covered by electronic
media including TVB, ATV, Cable TV, and press.
49. Aspirin and gastric cancer. Interview by ATV on 3 December 2003.
50. Colon cancer screening by virtual colonoscopy. Mingpao Daily, 10 December 2003.
51. GERD, Metrodaily newspaper, 24 December, 2003.
52. Constipation. Press conference, 5 February 2004. Covered by electronic
media including TVB, ATV, Cable TV, and press.
53. Chronic pancreatitis. Singpao Daily News 9 February, 2004
 16 BCY Wong - 18 August, 2010

54. Rapid test for Helicobacter pylori infection. Mingpao Daily newspaper, 11 February 2004.
55. NSAIDs reduce risk of gastric cancer. Doctor, 2004; 5(1): 18.
56. Common Gastrointestinal diseases. Invited talk for staffs in Sunhing Group of Companies. 19
February, 2004.
57. Irritable Bowel syndrome. Health program, Hong Kong Cable TV Limited. 26 Feb 2004.
58. H. pylori eradication prevent gastric cancer. Medical Tribune, Medimedia Asia, March 2004.
59. Gastro-esophageal reflux disease, Health program, Hong Kong Cable TV Limited. 31 March
2004.
60. Non-cardiac chest pain. The Sun Newspaper, A14, April 19, 2004.
61. Chest pain. Sing Tao Daily Newspaper, A10, April 19, 2004.
62. Colon cancer. Medical Focus- Health program, TVB Ltd, May 2004.
63. Stomach Cancer. Public talk, The Hong Kong Anti-Cancer Society, Lecture Theatre,
Hospital Authority, 5 June, 2004.
64. Colon Cancer, Economy Daily newspaper, A4, 9 August, 2004.
65. Colon Cancer, Sing Pao newspaper, A2, 9 August, 2004.
66. GERD rising trend in Hong Kong, Press conference, 12 August, 2004.
67. Colon Cancer. Oriental Daily newspaper A35, 18 August, 2004.
68. Helicobacter pylori infection. Lions Club of Central, Hong Kong, 19 August, 2004.
69. Colon cancer screening. Mingpao Newspaper D07, 23 August, 2004.
70. GERD. Singtao Newspaper E6, 23 August, 2004.
71. Belching and dyspepsia. Mingpao Newspaper D5, 1 September, 2004.
72. Common GI problems in Hong Kong. Parents magazine 2004; Sept, No. 148, pp70-1.
73. Early detection of colon cancer. Next Magazine 2004; Sept 9, Vol 757, pp138-9.
74. Screening of colon cancer. Metro Daily Newspaper 2004; Sept 17, pp 30 and 48.
75. Constipation. Mingpao Newspaper, 28 September , 2004.
76. Getting the word out on GERD. Doctor magazine Vol 5:9. pp8
77. Proton pump inhibitor best therapy for GERD. Medical Tribune 2004 Sept. pp7
78. GERD prevalence rising. Medical Tribune 2004 October.
79. Clonorchis sinesis. Mingpao Newspaper, 2004; Nov 4. ppA18.
80. Dye in food substances. Oriental Daily Newspaper, 2004 Oct 24, ppA24
81. Colouring of urine and stool. Sun Newspaper, 2004 Oct 24. ppA4
82. Colon cancer incidence on rising. Sing Pao 2004 Dec 6. pp A12
83. Suggest cooon cancer screening. Apple Daily Newspaper 2004 Dec 6, pp A17
84. Expert advise colon cancer screening. Oriental Daily Newspaper 2004 Dec 6, p A18
85. Faecal occult blood. Sun Newspaper 2004 Dec 6 pp A22
86. Fatal cases of Hepatitis E in Japan. Mingpao Daily 2004 Dec 14, pp A18
87. Expanding the horizons of small bowel endoscopy. Medical Tribune 2004 Nov pp i.
88. Cancer and Health Expo. Hong Kong Commercial News. 2004 Dec 19, ppC1
89. Screening for colon cancer. Sing Tao Daily News. 2004 Dec 21, pp E7.
90. Gene therapy for colon cancer, press conference 18 March, 2005, covered by electronic media
and all major newspapers.
91. Upper GI diseases, in Health program, Metro FM104, 4:00-5:00pm, 26 March, 2005.
92. Dyspepsia and belching. Hong Kong Economic Times 2005 Apr 15, pp A22.
93. Gene therapy. Next Magazine 2005 Apr 21.
94. Report on a study of health education and colon cancer screening. Press conference. 23 May
2005. Covered by eleven major newspapers in Hong Kong, and Radio Television Hong Kong.
95. Colon cancer. BackChat. RTHK Radio 3. 8:30am-9:30am. 30 May 2005.
 17 BCY Wong - 18 August, 2010

96. New non invasive test for non-cardiac chest pain diagnosis. 14 June 2005, covered by
electronic media (TV, radio) and all major newspapers in Hong Kong.
97. GERD and non-cardiac chest pain. 香港直播, TVB Jade 9:45am 15 June 2005.
98. GERD, Helicobacter pylori. 至 Fit 男女. Cable TV News channel 1. 15 June 2005.
99. Constipation, Hong Kong Economic Times 2005, July 12, ppA17
100. Risk factors for colon cancer. Oriental Daily 2005, July 12, ppA24
101. Novel endoscopic method for diagnosis and treatment of small intestinal diseases. Press
conference. 3 August 2005. Covered by major electronic media (TV, radio) and newspapers.
102. Double balloon enteroscopy. in Health program, Metro FM104, 4:00-5:00pm, 6 Aug, 2005.
103. Belching and gas. Mingpao weekly. September 3, 2005. pp110-113.
104. Helicobacter pylori. Oriental Daily September 10, 2005. pp.A20
105. Prevention of colon cancer. Oriental Daily, September 22, 2005, ppS2
106. Helicobacter pylori. Oriental Daily, October 4, 2005. pp A10.
107. Helicobacter pylori. AM730, October 4, 2005. pp1.
108. Press conference on colon cancer survey on behalf of Hong Kong Digestive Foundation,
October 6, 2005. Covered by ATV, Radio Television Hong Kong, and newspapers.
109. Balloon invasion benefits pateints with GI problems. Medical Tribune Oct 2005. pp viii
110. Gastroenteritis and appendicitis. Oriental Daily Nov 14, 2005 ppA24
111. Gastroenteritis and appendicitis. Sun Newspaper Nov 14, 2005, pp A14
112. Helicobacter pylori and peptic ulcers. Mingpao Newspaper Dec 1, 2005, pp G3.
113. Helicobacter pylori prevention. Sun Newspaper Dec 21, 2005, pp S5.
114. Gastroesophageal reflux disease. Hong Kong Economic Times Jan 26, 2006, ppA30.
115. Food poisoning. Headline Daily. 26 Jan 2006, pp2.
116. Colon cancer drug trials in Hong Kong. HK Economy Times Feb 16, 2006. ppA29
117. Prolonged fasting in wilderness. Singtao Daily Feb 20, 2006 ppA4.
118. Survival after prolonged fasting. Headline Daily Feb 20, 2006. pp 1.
119. Cancer chemoprevention. Next Magazine Mar 16, 2006. pp118-119.
120. GERD affects Hong Kong people. Oriental Daily April 2, 2006 ppA7.
121. Diagnostic tests for Helicobacter pylori. Next Magazine Apr 20, 2006, pp120
122. Diet and GI diseases. HK Economy Times Apr 25, 2006 ppC11.
123. GERD inflicts more than physical stress. Medical Tribune Apr 2006. pp11.
124. Female GERD risk factors. SingPao June 2, 2006. ppA09
125. Colon cancer prevalence in female. Apple Daily June 9, 2006, pp A14.
126. Gastritis in Hong Kong. SingTao Daily, June 16,2006, pp A10.
127. NSAID-induced gastritis. Apple Daily, June 16, 2006, pp A17.
128. NSAID can cause peptic ulcer. Sun Daily, June 16, 2006, pp A28.
129. Common GI diseases. In 最緊要健康. TVB Jade, 7pm, June 16, 2006.
130. Gastritis. In Sudden Weekly Magazine June 30, 2006, pp162.
131. Gastric cancer in blood group A subjects. In Apple Daily July 4, 2006, pp A16
132. GERD. In Sun Daily, August 23, 2006, ppS1
133. Charcoal and intestine. In Apple Daily August 23, 2006, pp A12
134. Biliary diseases. In Next Magazine, September 28, 2006, pp 47
135. Biliary disease and renal impairment. In Next Magazine, October 5, 2006, pp38-42
136. Colon cancer screening. In Sudden Weekly Magazine October 6, 2006, pp128-129
137. Alcohol intoxication. In Oriental Daily October 9, 2006, ppA26
138. Treatment of gastrointestinal bleeding. In Oriental Daily October 11, 2006. ppA11
139. Irritable bowel syndrome. In Sun Daily, October 11, 2006, ppS1
 18 BCY Wong - 18 August, 2010

140. Dyspepsia. In Ming Pao Weekly magazine, Nov 4, 2006, pp95.

141. Peptic ulcers. In Sun Daily, Nov 8, 2006, ppS4.
142. Drug trafficking in GI tract. In News of Cable TV News Channel, Nov 20, 2006.
143. Narcotics in GI track. In Apple Daily, Nov 21, 2006, ppA18
144. Narcotics in GI track, In New Daily, Nov 21, 2006, ppA2
145. Press conference in Asian GERD survey, Dec 19, 2006, covered by major newspapers.
146. Dyspepsia and indigestion. In Sing Pao, Dec 21, 2006, pp A14.
147. Dyspepsia. In Sun Daily, Dec 27, 2006, pp S6
148. Peptic ulcer. In Men’s Uno, January 2007, pp 242.
149. Inflammatory Bowel diseases. In Oriental Daily, January 3, 2007, pp A20.
150. Inflammatory Bowel diseases. In Sun Daily, January 3, 2007, pp A1.
151. GERD. In SingTao Daily, January 4, 2007, pp E4.
152. Constipation. In SingTao Daily, January 7, 2007, pp A8.
153. GERD. In Sing Pao Daily News, January 9, 2007, pp R1
154. Ingestion of foreign body. In Apple Daily, January 29, 2007, ppA8.
155. Gastroenteritis. In Sun Daily, January 31, 2007, ppS1.
156. Latest development in GERD. Health Plus Magazine, February 2007, pp11.
157. Laryngeal reflux and GERD. In Oriental Daily, February 28, 2007, pp A8.
158. GERD. In Next Magazine, March 1, 2007, pp106-109.
159. Ingestion of foreign body. In Hong Kong Economic Times, March 14,2007. pp A30
160. Endoscopic removal of foreign body. In AM730, March 14, 2007, pp 1
161. Foreign body ingestion. In Oriental Daily, March 15, 2007, pp A4
162. Crohn’s disease. Sing Tao Daily newspaper. April 11, 2007, pp A12
163. Ingestion of sharp objects. Sing Tao Daily newspaper. May 4, 2007, pp A8.
164. GERD. In Health Action Magazine. May 2007, pp 12-13.
165. Association between GERD and IBS. Hong Kong Economic Times May 22, 2007. pp C11.
166. Non cardiac chest pain. Apple Daily June 18, 2007. pp A14.
167. GERD. TVB Pleasure and Leisure . 1:15pm- 2:00pm, June 18, 2007.
168. Liver cirrhosis. Sun Daily, 25 July 2007, ppS2.
169. Spice and peptic diseases. Mingpao, 1 Aug 2007, pp A22.
170. GERD and non cardiac chest pain. Mingpao, 2 August 2007, ppA20.
171. Food poisoning. Oriental Daily, 10 August, 2007, pp A4.
172. Oyster and gastroenteritis. Sun Daily, 10 August 2007, pp A1.
173. Esophagitis management. Sing Pao, 15 August 2007, pp A9.
174. ERCP complications. Apple Daily, 19 August 2007, pp A2.
175. Colon cancer screening. Sun Daily, 8 Sept 2007. pp A21.
176. Functional GI diseases. Ming Pao Daily, 14 Sept 2007. pp A23.
177. Screening of digestive cancers. Next magazine, 20 Sept 2007, pp 134-138.
178. GERD-related non cardiac chest pain as distressing as cardiac chest pain. Press conference,
Faculty of Medicine, HKU, 7 Jan 2008.
179. Use of probiotics in GI diseases, HK Economic Times, ppA16, 26 Jan 2008.
180. Heartburn. Health Plus Magazine, February 2008, pp30-31.
181. Bile reflux and GERD. Apple Daily 19 February 2008, pp A14.
182. GERD and vocal cord polyps. TVB Pleasure and Leisure 1:15pm- 2:00pm, March 10, 2008.
183. Gastroenteritis. Apple Daily 12 March 2008, pp A1.
184. GERD and cardiac pain. Medical Tribune March 2008, pp V.
185. Star Mentorship Program, HKU SPACE Alumni Association, 11 April 2008.
 19 BCY Wong - 18 August, 2010

186. Aspirin and peptic ulcers, Apple Daily 13 May 2008, ppA16.
187. Colon cancer and diet. FANCL health magazine June 2008, pp 21-22
188. Screening of colon cancer. FANCL health magazine July 2008, pp 19-20
189. Early bird dinner and health. TV Baby of TVB Magazine, 30,June 2008, pp039
190. Dyspepsia. Metro Daily 5 Sept 2008, pp40 and 52.
191. Constipation, TVB Pleasure and Leisure 1:20pm- 2:10pm, 8 Sept, 2008.
192. Clonorchis and cholangiocarcinoma. Oriental Daily 12 Nov, 2008, ppA10.
193. Raw fish and clonorchis. The Sun, 12 Nov, 2008, pp A16.
194. Dyspepsia. Oriental Daily, 16 Nov, 2008, pp A7.
195. Stomach cancer risk factor and prevention press conference, covered by major newspapers
15 January 2009.
196. HK scholars win national science awards. Medical Tribune, Feb 2009.
197. GERD and asthma press conference, covered by major newspapers and electronic media, 22
April 2009.
198. GERD linked to poor asthma control. Medical Tribune, Jun 2009.
199. Constipation. Ming Pao 25 Jun 2009.
200. Fatty liver. Next Magazine, book A, pp 94-98. 2 July 2009.
201. Non acidic reflux in GERD. Next Magazine, book A, pp 108-112. 30 July 2009.
202. Duodenal ulcer. Apple Daily, pp A4, 19 Sept 2009.
203. Prevent gastric cancer, Oriental Daily News, Nov 1, 2009
204. Diet and Cancer public lecture, covered by Oriental Daily, Sun and Sing Pao, Nov 15, 2009.
205. Helicobacter pylori and peptic ulcer disease. Radio 1, RTHK, Dec 8, 2009.
206. Gastric cancer. Radio 1, RTHK, Dec 15, 2009.
207. Colon cancer stem cell. Radio 1, RTHK, Apr 7, 2010.
208. Small bowel enteroscopy. Radio 1, RTHK, Apr 14, 2010.
209. Colon cancer epidemiology and screening. Radio 1, RTHK, Apr 21, 2010.
210. Causes of gastric ulcer. Oriental Daily News, Jun 3, 2010
211. Colon cancer stem cell discovery. Press Conference covered by all major media, Jun 4, 2010.

12. PUBLIC EDUCATION CAMPAIGN

1. Chairman, Organizing Committee, Cancer and Health Expo 2004, at the Chinese
Resources Building, Wanchai, 5 Dec 2004. Co-organized by the Lions Club of Hong Kong
(Host) Charity Foundation and AIA Charity Foundation.
2. Chairman, Organizing Committee, Gastric cancer Expo 2006, at the Fuzhou City Hall,
Fuzhou, PR China on December 12 and 13, 2006. Co-organized by the Faculty of Medicine,
University of Hong Kong and the Health Bureau, Fuzhou Government, PR China
Free exhibitions, talks and blood test for Helicobacter pylori for the public in Fuzhou.
One lecture given by Nobel Laureate Dr Robin Warren to doctors in Fuzhou.
640 subjects received free testing of H. pylori.
 20 BCY Wong - 18 August, 2010

RESEARCH ACTIVITIES
1. JOURNAL EDITORIAL BOARD AND REVIEWER

Editor, Journal of Gastroenterology and Hepatology, since 2003

Editor, Digestive Disease Communications, since 2009.
Associate Editor-in-chief, Chinese Journal of Gastroenterology, since 2002
Associate Editor, Digestive Disease Watch, since 2004
Associate Editor-in-chief, Forum of Gastroenterology and Hepatology, since 2007
Associate Editor, Journal of Neurogastroenterology and Motility, since 2009.
Associate Editor, Journal of Chinese Clinical Medicine, Jan 2010- Dec 2013

Editorial Board, Chinese Journal of Gastroenterology, since 1999

Editorial Board, Journal of Clinical Oncology, Chinese edition, since 1999.
Editorial Board, Journal of Gastroenterology and Hepatology, since 2000
Editorial Board, Digestive Endoscopy, since 2001
Editorial Board, Journal of Digestive Diseases, since 2002
Editorial Board, MIMS Gastroenterology Guide, since 2002
Editorial Board, Modern Digestion and Intervention, since 2003
Editorial Board, European Review for Medical and Pharmacological Sciences, since 2004
Editorial Board, Alimentary Pharmacology and Therapeutics, since 2004
Editorial Board, World Journal of Gastroenterology, since 2004
Editorial Board, Gastrointestinal endoscopy, since 2004
Editorial Board, Carcinogenesis, 2005-2008
Editorial Board, Frontiers of Medicine in China, since 2007
Editorial Board, Cancer Epidemiology, Biomarkers & Prevention, since 2007.
Editorial Board, Medical Progress, since 2007
Editorial Board, Therapeutic Advances in Gastroenterology, since 2008.
Editorial Board, Cancer Prevention Research, since 2008.
Editorial Board, Clinical Journal of Gastroenterology, since 2008.
Editorial Board, Clinical and Experimental Gastroenterology, since 2008.
Editorial Board, Cochrane Upper Gastrointestinal and Pancreatic Diseases Group, since 2008
Editorial Board, Journal of Chinese Clinical Medicine, since 2009
Editorial Board, American Journal of Gastroenterology, since 2010

Reviewer for the following journals (alphabetical order)

ACS Medicinal Chemistry Letters, since 2010
Acta Pharmacologica Sinica, since 2007.
Alimentary Pharmacology and Therapeutics, since 2000.
American Journal of Gastroenterology, since 2003
American Journal of Pathology, since 2008
American Journal of Physiology - Cell Physiology, since 2008
American Journal of Physiology - Gastrointestinal and Liver Physiology, since 2004
Archives of Medical Research, since 2010
Asian Journal of Surgery, since 1999
BMC Health Services Research, since 5-2009.
 21 BCY Wong - 18 August, 2010

Cancer Biology and Therapy, since 9-2008

Cancer Chemotherapy and Pharmacology, since 2007.
Cancer Epidemiology, Biomarkers and Prevention, since 2002.
Cancer Investigation, since 2008
Cancer Prevention Research, since 1-2009.
Cancer Research, since 2003
Cancer, since 9-2008.
Carcinogenesis, since 2001.
Cell Biology International, since 2001.
Cell Proliferation, since 7-2009.
Cell Research, since 2008.
Chinese Journal of Digestive Diseases, since 2002
Chinese Journal of Gastroenterology, since 2003
Chinese Medicine, since 2007.
Clinical Cancer Research, since 2006
Clinical Drug Investigation, since 2001.
Clinical Gastroenterology and Hepatology, since 2006
Cytokine, since 2010
Digestion, since 2005
Digestive and Liver Disease, since 2001.
Digestive Diseases and Sciences, since 9-2008
Drugs, since 2007.
European Journal of Cancer, since 9-2008
European Journal of Gastroenterology and Hepatology, since 2001
Expert Opinion On Drug Safety, since 5-2010.
Expert Opinion on Investigational Drugs, since 4-2009.
Expert Opinion on Therapeutic Targets, since 7-2009.
Expert Review of Molecular Diagnostics, since 2008
Future Microbiology, since 2009
Future Oncology, since 2010.
Gastroenterology Research and Practice, since 4-2009.
Gastroenterology, since 2001
Gastrointestinal Endoscopy, since 2005
Gene, since 7-2009.
Genes and Immunity [impact factor 3.787], since 2006
Genetics in Medicine, since 2006
GUT, since 2002
Hepatology, since 2008.
Histology and Histopathology, since 2004.
Hong Kong Journal of Paediatrics, since 2002
Hong Kong Medical Journal, since 1997
International Journal for Biotechnology and Molecular Biology Research, since 2010
International Journal of Cancer, since 1999
International Journal of Obesity, since 2005
JAMA, since 2005
Journal of American Medical Association SEA, since 2000
Journal of Biological Chemistry, since 2006
 22 BCY Wong - 18 August, 2010

Journal of Cancer Research and Clinical Oncology, since 2-2009.

Journal of Cellular and Molecular Medicine, since 9-2008
Journal of Cellular Biochemistry, since 2007
Journal of Clinical Gastroenterology, since 2005
Journal of Endocrinology, since 2000
Journal of Experimental & Clinical Cancer Research, since 5-2009.
Journal of Gastroenterology, since 2010
Journal of Gastroenterology and Hepatology, since 1996
Journal of Neurogastroenterology and Motility, since 2009.
Journal of Pathology, since 2008.
Lancet Oncology, since 2007.
Medical Progress, since 1999
Microbial Pathogenesis, since 2002
Molecular Cancer Therapeutics, since 7-2009
Neoplasia, since 2003
Oncology, since 2003
Patient Preference and Adherence, since 2007.
Postgraduate Medical Journal, since 2009
PPAR Research, since 2010.
Preventive Medicine, since 2006
Proceedings of National Academy of Science USA, since 2004
Saudi Journal of Gastroenterology, since 2007.
The Hong Kong Practitioner, since 1999
The Journal of the National Cancer Institute, since 2005
The Lancet, since 2006
The Medical Letter, since 2004
Therapeutic Advances in Gastroenterology, since 9-2008
Tohoku Journal of Experimental Medicine, since 2010
Tumour Biology, since 2010

Reviewer for conference abstracts

1. 11th Asian Pacific Congress of Gastroenterology and 8th Asian Pacific Congress of
Digestive Endoscopy, March 2000, Hong Kong
2. Asia Pacific Digestive Week 2001, September, Sydney, Australia.
3. 2nd AACR Frontiers in Cancer Prevention Research, Oct 2003, Phoenix, USA
4. 2005 World Congress of Gastroenterology, September 2005, Montreal, Canada
5. 2006 Digestive Disease Week, May 2006, USA. Clinical Practice Epidemiology Abstract
Review Group.
6. 2006 Digestive Disease Week, May 2006, USA. Oncology Abstract Review Group.
7. 2006 Asian Pacific Digestive Week, November 2006, Philippines. Young Investigator
Award abstract review committee.
8. 2007 Digestive Disease Week, May 2007, USA Gastroduodenal abstract Review Group.
9. 2008 Asia Pacific Digestive Diseases Week, Sept 2008, India, abstract review.
10. 2008 Digestive Disease Week, May 2008, USA Esophageal, Gastric and duodenal
disorders abstract Review Group
 23 BCY Wong - 18 August, 2010

11. 2009 GI Cancers Symposium, January 2009, USA.

Reviewer for grants

1. National Natural Science Foundation/ Research Grant Council Joint Research Scheme,
University Grants Committee, Hong Kong, 2003.
2. Research Grants Council, University Grants Committee, Hong Kong, 2004.
3. Internal reviewer, Faculty of Medicine, for Research Grant Council CERG exercise 2005.
4. Faculty Research Grant, Hong Kong Baptist University, Hong Kong, 2005.
5. Internal reviewer, Faculty of Medicine, HKU, for Research Grant Council CERG exercise
2006-2007.
6. Grant reviewer, Health Research Board, Ireland, 2007.
7. Competitve Earmarked Research Grant, Research Grants Council, University Grants
Committee, Hong Kong, 2007.
8. Internal reviewer, Faculty of Medicine, HKU, for Research Grant Council CERG exercise
2007-2008.
9. National Health and Medical Research Council Project Grant SAF, Australia, 2008
10. Competitve Earmarked Research Grant, Research Grants Council, University Grants
Committee, Hong Kong, 2008.
11. Internal reviewer, Faculty of Medicine, HKU, for Research Grant Council CERG exercise
2008-2009.
12. Internal reviewer, Faculty of Medicine, HKU, for Research Grant Council CERG exercise
2009-2010.
13. Grant Reviewer, Dutch Digestive Foundation 2009.

Reviewer for awards

1. Selection committee on AACR-NCI International Investigator Opportunity Grants for the
AACR Frontiers in Cancer Prevention Research Meeting, USA, November 2008.
 24 BCY Wong - 18 August, 2010

2. RESEARCH GRANT (Total amount: HK$ 66,371,147 + RMB 320,000

+US$ 2,000.00)

PRINCIPAL INVESTIGATOR (Total amount : HK $18,759,541)

Competitive grants
1. Research Grant Committee (RGC) Earmarked grant 1999-2000 (HKU 7010/99M)
Induction of apoptosis by selective protein kinase C- and cyclooxygenase-2 inhibition:
novel target for gastric cancer treatment.
Amount awarded: HK$ 709,500. Duration: 01/09/1999-31/08/2001

2. Research Grant Committee (RGC) Earmarked grant 2001-2002 (HKU 7309/01M)

Molecular basis of the anti-tumor activities of specific cyclooxygenase-2 inhibitors
Amount awarded: HK$ 699,600 Duration: 01/09/2001-31/08/2003

3. Outstanding Young Researcher Award 2001-2002, The University of Hong Kong.

Amount awarded: HK$ 300,000

4. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7482/03M)

Regulation of hTERT in relation to non-steroidal anti-inflammatory drugs in gastrointestinal
carcinogenesis.
Amount awarded: HK$ 1,256,000 Duration: 01/09/2003-31/08/2006

5. Research Grant Committee (RGC) Earmarked grant 2004-2005 (HKU 7472/04M)

Role of cyclooxygenase in helicobacter pylori-induced gastric carcinogenesis
Amount awarded: HK$1,521,500 Duration: 1/01/2005-31/12/2006

6. Outstanding Researcher Award 2005-2006, The University of Hong Kong.

Amount awarded: HK$ 250,000

7. Michael Kadoorie Funded Research in Cancer Genetics

Helicobacter pylori infection and CpG island methylation in gastric carcinogenesis
Amount awarded: HK$ 1,535,048 Duration: 01/01/2005-31/12/2007

Internal grants
1. Committee on Research and Conference Grants 1997-98 (337/041/0080)
Role of protein kinase C signal transduction pathway in cell proliferation, apoptosis and
cell cycle phase distribution in human gastric carcinoma cells
Amount awarded: HK$ 95,000. Duration: 01/07/1997-30/06/1998

2. Committee on Research and Conference Grants 1998-99 (10202149/27833/20600/323/01)

The role of free radicals in peptic ulcer and gastric cancer
Amount awarded: HK$ 116,000. Duration: 01/07/1998-31/10/1999

3. International Research Program on Traditional Chinese and Natural Medicine, University of

Hong Kong, 1999
 25 BCY Wong - 18 August, 2010

Effect of Shark cartilage on colorectal cancer.

Amount awarded: HK$ 150,000.

4. HKU Foundation- Medical Endowment, Gastrointestinal Research grant, 2002-2003.

Amount awarded: HK$ 750,000

5. University Research Committee Seed funding for basic research 2003

Effect of XAF1 gene on tumour growth in gastric and colon cancer
Amount awarded: HK$ 120,000. Duration: 01/01/2003-31/12/2003

6. University Research Committee Matching Grant Scheme-First Phase

DONPJ-Gastroenterological Research
Amount awarded: HK$ 453,750 Duration: 16/09/2003-

7. University Research Committee Matching Grant Scheme-2nd Phase

DONPJ-Gastroenterological Research
Amount awarded: HK$ 90,000 Duration: 16/09/2003-

8. University Research Committee Matching Grant Scheme-2nd Phase

DONPJ-Gastroenterological Research
Amount awarded: HK$ 7500 Duration: 16/09/2003-

9. HKU Foundation- Mrs Tam Wah Ching Fund for Chinese Western Medical Research 2003
Amount awarded: HK$ 500,000

10. Seed Funding Program for basic research, URC, University of Hong Kong 2003-2004
Role of Bcl-2 family proteins in non-steroidal anti-inflammatory drug-induced apoptosis of
gastric cancer
Amount awarded: HK$ 120,000 Duration: 01/02/2004-31/01/2005

11. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7482/03M)
Regulation of hTERT in relation to non-steroidal anti-inflammatory drugs in gastrointestinal
carcinogenesis.
Merit awarded: HK$ 50,000 Duration: 01/09/2003-31/08/2006

12. Government Matching Grant Scheme

Gene therapy targeting apoptosis related genes in gastrointestinal cancers
Amount awarded: HK$ 543,750 Duration: 17/05/2004

13. Research Grant Committee (RGC) Earmarked grant 2004-2005 (HKU 7472/04M)
Role of cyclooxygenase in helicobacter pylori-induced gastric carcinogenesis
Merit awarded: HK$50,000 Duration: 01/01/2005-31/12/2006

14. Stanley Ho Alumni Challenge Matched Fund 2006-7

GI cancer research fund on FHL2 and cell cycle in GI cancer
Amount awarded: HK$ 500,000
 26 BCY Wong - 18 August, 2010

15. GRF Incentive Award 2008-09 (HKU 778308M)

Isolation and characterization of cancer stem cells with tumor-initiating and metastatic
properties in colorectal cancer
Amount awarded: HK$30,000 Duration: 1/11/2008-30/6/2010

16. Government Matching Grant Scheme (4th phase)

Colon cancer stem cell characterization
Amount awarded: HK$ 37,500 Duration: 28/11/2008-30/10/2009

17. Government Matching Grant Scheme (2nd phase)

Role of PDX1 in GI carcinogenesis-Phase I
Amount awarded: HK$ 48,750 Duration: 20/1/2009

18. Government Matching Grant Scheme (3rd phase)

Role of PDX1 in gastrointestinal cacinogenesis-Phase II
Amount awarded: HK$ 187,500 Duration: 13/1/2009

19. Government Matching Grant Scheme (3rd phase)

Tasrgeting XAF1 in treatment of GI cancer
Amount awarded: HK$ 571,543.42 Duration: 13/1/2009

Industrial grants
1. A prospective randomized double-blind placebo-controlled study to evaluate the efficacy
. of lansoprazole in functional dyspepsia in Chinese
. Amount awarded: HK$ 200,000. From: Takeda IMC Chemical Ltd

2. Efficacy of ranitidine bismuth citrate in the eradication of Helicobacter pylori (1998)

Amount awarded: HK$ 150,000. From: Glaxo Wellcome Hong Kong.

3. Quadruple therapy for treatment of Helicobacter pylori related duodenal ulcers

Amount awarded: HK$ 150,000. From: Takeda IMC Chemical Ltd

4. Use of rabeprazole-based triple therapy compared with standard treatment for Helicobacter
pylori (2000)
Amount awarded: HK$ 340,000 From: Eisai Hong Kong Ltd.

5. Evaluation of the efficacy of furazolidone-based triple therapy for the treatment of

refractory Helicobacter pylori infection.(2000)
Amount awarded: HK$ 50,000 From: Astra Zeneca Ltd

6. A multicenter, randomized, placebo-controlled double-blind study to determine the effect

of MK-0966 on the recurrence of neoplastic polyps of the large bowel in patients with a
history of colorectal adenomas. (2000)
Amount awarded: HK$ 3,793,000 From: Merck, Sharp & Dohme (Asia) Ltd
 27 BCY Wong - 18 August, 2010

7. A randomized, double-blind, placebo-controlled study of the efficacy and safety of

celecoxib (SC-58635) in the prevention of colorectal sporadic adenomatous polyps (2001)
Amount awarded: HK$ 1,404,000 From: Pharmacia Corporation Ltd

8. A prospective randomized phase II study of standard schedule versus dose rate constant
schedule gemcitabine in inoperable hepatocellular carcinoma (2001)
Amount awarded: HK $ 249,600 From: Eli Lilly Co Ltd

9. A randomized study on two regimes in treatment of resistant Helicobacter pylori infection

(2001)
Amount awarded: HK $ 300,000 From: Eisai Hong Kong Ltd

10. A randomized placebo controlled study of OSI-774 (Tarceva) plus gemcitabine in patients
with locally advanced, unresectable or metastatic pancreatic cancer. (2002)
Amount awarded: HK $ 300,000 From: OSI Pharmaceuticals, Inc

11. A randomized , comparative, double-blind, parallel group, multicenter phase IIIa study to
eradicate Helicobacter pylori, heal gastric ulcer and prevent relapse in gastric ulcer subjectw
with esomeprazole in combination with amoxicillin and clarithromycin (2002)
Amount awarded: HK$ 300,000 From: AstraZeneca

12. Research on second line treatment of Helicobacter pylori infection (2003)

Amount awarded: HK$ 120,000 Takeda Chemical Ind (Taiwan) Ltd

13. Research on non erosive gastroesophageal reflux disease (2003)

Amount awarded: HK$ 150,000 From: AstraZeneca

14. Research on proton pump inhibitor and noncardiac chest pain (2003)
Amount awarded: HK$ 20,000 From: Eisai Co Ltd

15. Research on year prevalence of gastroesophageal reflux disease (2003)

Amount awarded: HK$ 40,000 From: AstraZeneca

16. Research on laryngo-pharyngeal reflux disease (2004)

Amount awarded: HK$ 500,000 From: Eisai Co Ltd

CO-INVESTIGATOR (Total amount : HK $47,611,606+ RMB 320,000)

Competitive grants

1. Research Grant Committee (RGC) Earmarked grant 1997-1998 (HKU 7291/97M)

Assessment of helicobacter pylori and dietary factors in gastric carcinogenesis: correlation
with cell proliferation, apoptosis and intracellular signal transduction pathway.
Amount awarded: HK$ 686,880. (PI- Prof SK Lam)
 28 BCY Wong - 18 August, 2010

2. Research Grant Committee (RGC) Earmarked grant 1999-2000 (HKU 7002/99M)

Chemoprevention of gastric cancer by treatment of Helicobacter pylori infection.
(PI- Prof SK Lam)
Amount awarded: HK$ 2,175,800. Duration: 01/09/1999-31/08/2002

3. Research Grant Committee (RGC) Earmarked grant 2001-2002 (HKU 7256/01M)

Chemoprevention of gastric cancer by intervention with Helicobacter pylori and
cyclooxygenase pathway
Amount awarded: HK $ 2,000,000 (PI- Prof SK Lam)

4. Research Grant Committee (RGC) Earmarked grant 2001-2002 (HKU 7318/01M)

Topographic association of helicobacter pylori infection with apoptosis and cell
proliferation in the human stomach: roles of H. pylori-induced antralization in the
pathogenesis of gastric cancer
Amount awarded: HK $ 699,600 (PI- Dr Harry Xia)

5. Research Grant Committee (RGC) Earmarked grant 2002-2003 (HKU 7281/02M)

Delineation of the co-regulatory role of cyclooxygenase-2 and 12- lipoxygenase in colorectal
cancer: a causal relationship with ulcerative colitis and cigarette smoking
Amount awarded: HK$ 1,164,000 (PI- Prof CH Cho)

6. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7493/03M)

Molecular and genetic mechanisms of helicobacter pylori-induced antralization in gastric
carcinogenesis (PI- Dr Harry Xia)
Amount awarded: HK$1,572,000 Duration: 1/09/2003-31/08/2005

7. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7487/03M)

Non-cardiac chest pain in Chinese population
Amount awarded: HK$ 936,000 (PI- Dr RWM Wong)

8. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7445/03M)

Molecular basis of alcohol-induced birth defects, the critical role of Pax6
Amount awarded: HK$ 1,203,000 (PI- Dr MCM Lin)

9. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7422/03M)

Molecular basis for the telomere dysfunction and anti-tumour activities of a C-terminal
polypeptide of human telomerase reverse transcriptase (hTERTC27)
Amount awarded: HK$ 624,000 (PI- Prof HF Kung)

10. Innovation and Technology Fund, Government of HKSAR

Cancer Gene Therapy using a novel anti-cancer polypeptide hTERTC27 delivered by a
novel AAV and Adenovirus Cocktail vector system (PI- Dr MCM Lin)
Amount awarded: HK 4,258,000 Duration: 06/2003-05/2006

11. Research Grant Committee (RGC) Earmarked grant 2004-2005 (HKU 7405/ 04M)
Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene
delivery system (PI- Prof SK Lam)
 29 BCY Wong - 18 August, 2010

Amount awarded: HK$939,968 Duration: 01/01/2005-31/12/2006

12. Research Fund for the Control of Infectious Diseases, Health and Health Services Research
Fund
Hepatitis B or Hepatitis C viral infection and genotypes-Which subgroup is more prone to the
development of hepatocellular carcinoma? A systematic review (PI-Dr. JQ Huang)
Amount awarded: HK$ 359,654.00 Duration: 29/01/2004-28/07/2005

13. Research Grant Committee (RGC) Earmarked grant 2006-2007 (HKU 7520/ 06M)
The roles of survivin in hematopoiesis, angiogenesis and tumorigenesis in a zebrafish knock-
down and transgenic model.
Amount awarded: HK$ 1,032,500 (PI- Dr AYH Leung)

14. Research Grant Committee (RGC) Earmarked grant 2008-2009 (HKU 7755/08M)
Structure-function study of XIAP-Associated Factor 1 (XAF1) – structure determinations of
XAF1 and its complex with X-Linked Inhibitor of Apoptosis Protein (XIAP) by multi-
dimensional NMR spectroscopy. (PI- Dr. KH Sze)
Amount awarded: HK$1,103,765 Duration: 01/2009-12/11

15. National Natural Science Funds (No. 30872973)

The synergic role and regulatory mechanism of tumor suppressor XAF1 in Sulfone’s anti-tumor
activity.
Amount awarded: RMB 320,000. (PI- Dr. Li Fen Yu, Shanghai Ruijin Hospital, Shanghai Jiao
Tong University School of Medicine). Duration: 01/2009-12/2011

Internal grants

1. Committee on Research and Conference Grants

Relationship of Helicobacter pylori and gastric cancer in China
Amount awarded: HK$ 100,000 Duration: 1993-1996

2. Committee on Research and Conference Grants 1998-99 (10202149/27833/20600/323/01)

Macrophage migration inhibitory factor expression in chronic gastritis and peptic ulcer in
patients with Helicobacter pylori infection
Amount awarded: HK$ 90,000.

3. Committee on Research and Conference Grants 2000-2001

Apoptosis and ulcer healing in the stomach: effects of cigarette smoking, alcohol drinking and
other risk factors.
Amount awarded: HK $120,000.

4. University Department of Medicine Research Grant 2001

Role of MIF in H. pylori induced gastric inflammation. (PI- Dr Harry Xia)
Amount Awarded: HK$ 100,000.
 30 BCY Wong - 18 August, 2010

5. University Research Committee Seed funding for basic research 2001

Expression of MIF in response to H. pylori and its role in regulation of inducible nitric oxide
synthase, TNF-alpha and IL-1 in cell cultures (PI- Dr Harry Xia)
Amount Awarded: HK$ 117,000. Duration: 1/05/2001-30/04/2002

6. Seed funding for basic research 2002-2003

Molecular and genetic mechanisms of Helicobacter pylori induced antralization in gastric
carcinogenesis. (PI- Dr Harry Xia)
Amount awarded: HK $119,000. Duration: 01/02/2002-31/01/2003

7. University Research Committee Seed funding for basic research 2003

Gene therapy for GI cancer by targeting survivin with adeno-associated virus. (PI- Prof SK Lam)
Amount awarded: HK$ 120,000. Duration: 01/01/2003-31/12/2003

8. University Research Committee Seed funding for basic research 2003

Homeobox genes in gastric carcinogenesis (PI- Dr Harry Xia)
Amount awarded: HK$ 120,000. Duration: 1/1/003-31/12/2003

9. University Department of Medicine Research Grant 2001

Cell proliferation and crypt fission in normal colonic mucosa, inflammatory bowel disease, pre-
neoplastic conditions of colon and colonic cancer (PI- Dr WM Wong)
Amount Awarded: HK$ 100,000.

10. University Department of Medicine Research Grant 2001

E-cadherin and gastic cancer. (PI- Dr AOO Chan)
Amount Awarded: HK$ 100,000.

11. University Department of Medicine Research Grant 2002

A randomized double-blinded placebo controlled study to determine the effects of COX-2
inhibitor (Rofecoxib) on proliferation characteristics of colonic mucosa in patients with
sporadic adenomatous polyps. (PI- Dr WM Wong)
Amount Awarded: HK$ 75,000.

12. University Department of Medicine Research Grant 2002

To investigate the degree of acid suppression required for control of the acid reflux and
symptomatic relief of GERD (PI- Dr KC Lai)
Amount Awarded: HK$ 100,000.

13. University Department of Medicine Research Grant 2002

Study on the effect and mechanism of XAF-1 gene on tumorigenesis in gastric and colon cancer.
(PI- Dr SP Tu)
Amount Awarded: HK$ 75,000.

14. University Development Fund, 2003-2006

Bio-Pharmaceutical Development Center. (PI- Prof Ricky Man)
Amount awarded: HK$ 25,850,000
 31 BCY Wong - 18 August, 2010

15. Research Grant Committee (RGC) Earmarked grant 2003-2004 (HKU 7493/03M)
Molecular and genetic mechanisms of helicobacter pylori-induced antralization in gastric
carcinogenesis (PI- Dr Harry Xia)
Merit Awarded: HK$ 50,000 Duration: 1/09/2003-31/08/2005

16. Seed Funding for Basic Research Program 2003-2004, University of Hong Kong
Long-term use of non-steroidal anti-inflammatory drugs and development of colorectal
tumours: a systematic review and meta-analysis (PI- Dr JQ Huang)
Amount awarded: HK$ 120,000

17. Seed Funding for Basic Research Program 2003-2004, University of Hong Kong
c-Jun NH2-terminal kinase 1 modulates apoptosis of gastric cancer cells through the
upregulation of XAF1 (PI- Prof SK Lam)
Amount awarded: HK$ 120,000

18. Seed Funding for Basic Research Program 2003-2004, University of Hong Kong
Role of cyclooxygenase in Helicobacter pylori-induced gastric carcinogenesis
(PI- Dr Harry Xia)
Amount awarded: HK$ 120,000 Duration: 01/02/2004-31/01/2005

19. Research Grant Committee (RGC) Earmarked grant 2004-2005 (HKU 7405/ 04M)
Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene
delivery system (PI- Prof SK Lam)
Merit awarded: HK$50,000 Duration: 01/01/2005-31/12/2006

20. Seed grant for RAP/PDF (February 2004-July 2005)

Prevention of colorectal tumors with nonsteroidal anti-inflammatory drugs: a systematic review
and meta-analysis (PI-Dr. JQ Huang)
Amount awarded: HK$ 8600 Duration: 31/10/04-31/8/05

21. Seed grant for RAP/PDF (February 2004-July 2005)

Stress stimulation negatively regulates the expression of XAF1 gene in gastrointestinal cancer
cells via the transcription factor HSF (PI-Dr.JD Wang)
Amount awarded: HK$ 24,000 Duration: 31/10/04-31/8/05

22. Seed grant for RAP/PDF (February 2004-July 2005)

Effect of non-steriodal anti-infalammatory drugs on Helicobacter pylori-induced gastric
carcinogenesis (PI-Dr. Harry Xia)
Amount awarded: HK$ 39,600 Duration: 31/10/04-31/8/05

23. Seed Funding for Basic Research

Role of microphage migration inhibitory factor in Helicobacter pylori-induced gastric
carcinogenesis (PI-Dr. Harry Xia)
Amount awarded: HK$ 120,000 Duration: 01/01/2005-31/12/2005

24. Seed Funding for Basic Research Program 2006-2007, University of Hong Kong
 32 BCY Wong - 18 August, 2010

Expression and role of homeobox gene PDX1 in gastric carcinogenesis

(PI- Dr Harry Xia)
Amount awarded: HK $80,000 Duration: 1/4/2006-31/3/2007

25. Seed funding program for basic research, HKU

Role of FHL2 in apoptosis of gastric cancer (PI- Prof SK Lam, Co-I Dr L Qiao)
Amount awarded: HK$60,000 Duration: 5/1/2007- 30/4/2008

26. Seed Funding Program for Basic Research 2006-2007. The University of Hong Kong
Simultaneous activation of PPAR and inhibition of XIAP in human colorectal cancer cells:
effects on apoptosis and angiogenesis. (PI- Dr. Liang Qiao)
Amount Funded: HK$100,800.

27. Seed Funding Program for Basic Research 2007-2008. The University of Hong Kong
Interaction of FKL2 and CDH1 in gastric cancer (PI- Dr. Liang Qiao)
Amount Funded: HK$100,000. Duration: 4/2007-3/2008

28. Seed Funding Program for Basic Research 2008-2009. The University of Hong Kong
Interaction of XIAP and Jagged1 in colon cancer (PI- Dr. Liang Qiao)
Amount Funded: HK$80,000. Duration: 4/2008-6/2009

29. Seed Funding Programme for Basic Research, 2008, University of Hong Kong
Characterization of the interaction between XAF1 and FHL2 in carcinogenesis and
differentiation of gastrointestinal cancers (PI- Dr. JD Wang)
Amount awarded: HK$120,000 Duration: 01/20081-12/2008

30. Small Project Funding, University of Hong Kong

The study of XAF1 as a novel target gene of p53 (PI-Dr B Zou)
Amount awarded: HK $ 54,502 Duration: 01/08/2008 to 31/07/2009

Industrial grants

1. Study on ranitidine bismuth citrate triple therapy for five or seven days in treatment of
Helicobacter pylori. (1997-1999)
Amount awarded: HK$ 21,000. From: Glaxo Wellcome China Ltd.

2. Study on use of clarithromycin in treatment of duodenal ulcer and Helicobacter pylori

infection. (1997-1999)
Amount awarded: HK$250,000 From: Abbott Laboratory.

3. Clinical Trials Projects

Amount awarded: HK$ 131,937.23 From AstraZeneca HK Ltd.

4. Study on proton pump inhibitor and non cardiac chest pain. (2003)
Amount awarded: HK$20,000 From: Eisai Co. Ltd.
 33 BCY Wong - 18 August, 2010

3. Donation (Total amount : HK $17,570,000+US$ 2,000.00)

1. Sakura Einetechnical Co.,Ltd Research Grant

US$1,000.00 July 2001

2. Serim Research Corporation Research Fund

US$ 1,000.00 July 2001

3. HKU Foundation-Medical Endowment-Gastrointestinal research

HK$750,000 October 2002

4. Kwok Sau Po Gastroenterology Research Fund

HK$ 500,000 September 2003

5. Shun Tak District Min Yuen Tong Gastroenterology Research Fund

HK$ 1,000,000 August 2004

6. Gordon YH Chiu Stomach Cancer Research Fund

HK$ 12,500,000 May 2005

7. Tam Wah Ching Gastroenterology Research Fund

HK$ 500,000 August 2003

8. Lo Ka Chung Charitable Foundation Limited

HK$ 1,000,000 July 2006

9. Winter Harvest Investments Limited for colon cancer research

HK$ 20,000 February 2007

10. Wai Tak Endoscopy Research Fund

HK $ 1,200,000 September 2007.

11. Wong Hung & Sons Fund

HK $ 100,000 January 2008.

Solicited Donation for Queen Mary Hospital

1. Gordon YH Chiu and Family- naming of Gordon Chiu Gastroenterology Center, K18S.
HK$ 7,500,000 May 2005

2. Wong Hung and Family – in support of new endoscopy service

HK $ 100,000 January 2008.
 34 BCY Wong - 18 August, 2010

4. Patent
1. Adeno-associated virus-mediated survivin mutants and methods related thereto. US
provisional patent application number US60/615,916 filed 5 October 2004.

2. A novel gold (III) complex 1a induces apoptosis and inhibits tumor growth in colon cancer.
(Co-I: 25%) – under filing with Versitech, HKU

5. ADVISOR TO BIOTECHNOLOGY & PHARMACEUTICAL INDUSTRY

1. Consulting work to Shanghai Health Digit Limited, in Shanghai, May 13, 2001
2. Advisory group to AstraZeneca meeting, in Atlanta, USA, May 22, 2001.
3. Advisory Board, somatostatin analogues for hepatocellular carcinoma, Novartis, at Amsterdam,
The Netherlands, May 30, 2001.
4. Takeda Roundtable discussion, H. pylori and gastric cancer- west meets east, at World
Congress of Gastroenterology, Bangkok, Thailand, February 25, 2002
5. Articulum program- Asia Pacific Region, Pharmacia and Pfizer, Ho Chi Minh City, Vietnam,
June 22, 2002.
6. FAST expert advisory board – Eisai, at Bali, Indonesia, August 30, 2002.
7. Articulum program- Asia Pacific Region, Pharmacia and Pfizer, Sydney, Australia, March, 2003.
8. FAST expert advisory board – Eisai, at Fukuoka, Japan, November 8, 2003
9. GAST expert advisory board on Chest Pain – AstraZeneca, New York, USA, December 8, 2003
10. GAST Asia expert advisory board on GERD– AstraZeneca, Guangzhou, China, March 23,
2004
11. Articulum program Global advisory board – Pfizer, Budapest, May 28, 2004.
12. GAST expert advisory board on Chest Pain – Astrazeneca, Stockholm, Sweden, June 7, 2004
13. Chairman, FAST expert advisory board – Eisai, in Hong Kong, September 20, 2004.
14. GAST expert advisory board on Definition of GERD – Astrazeneca, Amsterdam, The
Netherlands, January 2005
15. GAST expert advisory board on Definition of GERD – Astrazeneca, Rome, Italy, June 2005
16. FAST expert advisory board – Eisai, in Bangkok, Thailand November 26, 2005.
17. FAST expert advisory board – Eisai, in Tokyo, Japan, 10 June, 2006.

6. STEERING COMMITTEE IN RESEARCH PROJECT

1. PreSAP (Randomized, double-blind, placebo-controlled study of the efficacy and safety of

Celecoxib in the Prevention of colorectal sporadic adenomatous polyps) study – international
multicenter prospective study.
Co-Principal investigators: Professor Bernard Levin, Professor Nadir Arber.
Industrial partner – Pharmacia Corporation.

2. APPROVe (A multicenter, randomized, parallel group, placebo-controlled, double-blind

study with in-house blinding to determine the effect of 156 weeks of treatment with mk-
0966 on the recurrence of neoplastic polyps of the large bowel in patients with a history
 35 BCY Wong - 18 August, 2010

of colorectal adenomas.
Publication committee
Industrial partner – Merck Sharp & Dohme

7. EXPERIENCE IN SETTING UP RESEARCH LABORATORY

1. Set up and running of the Simon KY Lee Digestive Disease Laboratory, K18S , Room 1840,
Queen Mary Hospital.

State of the art gastrointestinal investigations including 13C-urea breath test, Helicobacter
pylori serological assays, cagA strain serological assays, gastrin, gastric juice and acid
stimulation studies.
Installation of the first mass spectrometer in Asia for the 13C-urea breath test.

2. Set up and running of the Helicobacter pylori culture laboratory, K18S, Room 1839, Queen
Mary Hospital.
Culture and drug sensitivity assay of Helicobacter pylori , molecular techniques including
PCR, RAPD, SSCP in detection of Hp and its genomic analysis.

3. Set up and running of the Gastrointestinal oncology research, Wellcome Laboratory, Queen
Mary Hospital.
Stomach and colon cancer cell culture technique, in-depth research in apoptosis, signal
transduction pathway, oncogenes and tumour suppressor genes.

8. SCHOLARLY ACTIVITIES
1. Additional Examiner
Ph D degree in Pharmacology, Mr CHOW Yip Chuen, 1997.
2. Internal Examiner
Ph. D degree in Pharmacology, Mr. LI Yang, 1999.
3. Internal Examiner
Ph. D degree in Pharmacology, Ms GUO Xin, 2000
4. Internal Examiner
Ph.D. degree in Medicine, Mr FAN Xiao Ming, 2001
5. External Examiner
Ph.D. degree in Medicine, Ms Zhang Siu Yan, Institute of Digestive Diseases, Xijing
Hospital Fourth Military Medical University, Xian, China, 2001
6. Internal Examiner
M. Phil degree in Pharmacology, Miss SHIN Vivian Yvonne, 2001
7. Chairman of Examining Committee
MPhil. Degree in Institute of Molecular Biology, Miss WONG Nga Yi Queenie, 2002
8. Chairman of Examining Committee
Ph.D degree, Miss LI Nan, 2002
9. External Examiner, (2002-2008)
Degree course, Bachelor of Chinese Medicine and BSc (Hons) Biomedical Science, Hong
Kong Baptist University, Hong Kong.
10. Internal Examiner
 36 BCY Wong - 18 August, 2010

Ph.D. degree in Pharmacology, Mr LIU Shiu Lam Edgar, 2003

11. Internal examiner
Ph.D. degree in Medicine, Mr YUAN Hejun, 2003
12. External examiner
M. Phil deree in Department of Applied Biology & Chemical Technology, The Hong
Kong Polytechnic University, Ms Tsui Sam Mui, 2003
13. Chairman of Examining Committee
MPhil. degree in Institute of Molecular Biology, Miss CHEUNG Yuen Ting, HKU, 2003
14. Additional Examiner
Ph.D degree in Paediatrics, University of Hong Kong, Mrs BHATIA Inderjeet, 2004
15. Internal Examiner
Ph.D degree in Pharmacology, Ms Vivian Yvonne SHIN, University of Hong Kong, 2004
16. Internal Examiner
PhD degree in Medicine, Mr WONG Ka Ho Danny, University of Hong Kong 2004.
17. Additional Examiner
M. Phil degree in Medicine, Ms Qing ZHANG, University of Hong Kong, 2004
18. Internal Examiner
MD degree in Medicine, Dr LIU Chi Leung, University of Hong Kong, 2004.
19. Chairman of Examining Committee
Ph.D. degree in Institute of Molecular Biology, Miss LUM Ching Tung, HKU, 2004
20. Examiner
Hong Kong College of Physician Advanced Internal Medicine Exit Assessment,
June 2005.
21. Chairman of Examining Committee
Ph.D. degree in Surgery, Mr LI Xiaosong, HKU, 2005
22. Internal Examiner
MD degree in Medicine, Dr LAU Hung, University of Hong Kong, 2005.
23. Internal Examiner
Ph.D degree in Surgery, Mr TANG Chi Man Terence, University of Hong Kong, 2005.
24. Internal Examiner
M.Phil degree in Paediatrics, Mr YEUNG On Lit, University of Hong Kong, 2006.
25. Chairman of Examining Committee
Ph.D. degree in Surgery, Mr LUO Ying, HKU, 2006
26. Examiner
Hong Kong College of Physician Advanced Internal Medicine Exit Assessment,
June 2006.
27. External Examiner
M.Phil degree in CMTD, Ms TIN Man Ying, Hong Kong Baptist University, Jun 2006.
28. Internal Examiner
Ph.D degree in Medicine, Ms PANG Wen Chi Roberta, University of Hong Kong, 2006.
29. Internal Examiner
Ph.D degree in Medicine, Dr KWOK Kwan Ho, University of Hong Kong, 2006.
30. Internal Examiner
Ph.D degree in Pathology, Mr ZHAO Wei, University of Hong Kong, 2006.
31. Internal Examiner
Ph.D degree in Pathology, Ms GUO Dongli, University of Hong Kong, 2007.
32. Chairman of Examining Committee
 37 BCY Wong - 18 August, 2010

Ph.D. degree in Microbiology, Mr GAO Yi, HKU, 2007.

33. Chairman of Examining Committee
M.Phil degree in Surgery, Mr LUI, Lik Hang Eric, HKU, 2007.
34. Internal Examiner
M.Phil degree in Surgery, Mr CHEUNG Chi Man, HKU, 2007.
35. Chairman of Examining Committee
M.Phil degree in Surgery, Miss CHEUNG Ka Yee Cindy, HKU, 2008.
36. Internal Examiner
M.Phil degree in Surgery, Mr HUI King Cheung, HKU, 2008.
37. Internal Examiner
M.Phil degree in Surgery, Miss CHAN Wing San, HKU, 2008.
38. External Examiner
PhD degree in Medicine, Ms LI Julia, Chinese University of Hong Kong, Jun 2009.
39. External Examiner
PhD degree in Medical Sciences, Ms WANG, Xin, Chinese University of Hong Kong, Aug
2009.
40. Internal Examiner
M.Phil degree in Medicine, Mr YEUNG Pok, University of Hong Kong, Sep 2009.
41. Internal Examiner
MS degree in Surgery, Mr FAN King Man Joe, University of Hong Kong, May 2010.

9. INVITED LECTURES
1. Chemoprevention of colorectal cancer- a molecular approach
in Scientific meeting of Hong Kong Society of Gastroenterology,
Hong Kong, September, 1996.

2. Report of the Changle Gastric Cancer Study Group

in Second National Symposium on Helicobacter pylori , Chinese Medical Association.
Guangzhou, China, April 1997.

3. Helicobacter pylori infection and gastric cancer

in First Meeting of the Korean Society of Helicobacter pylori studies,
Seoul, Korea, June 1997.

4. Diet and gastric cancer

in 14th Asia Pacific Cancer Conference, and 4th Hong Kong International Cancer congress,
Hong Kong, November 1997.

5. Epidemiology, diet and Helicobacter pylori in gastric cancer

in Alimentary Disease Week, Hong Kong, December 1997.

6. Helicobacter pylori: from theory to practice

in Scientific symposium, Alimentary Disease Week, Hong Kong, December 1997.

7. Helicobacter pylori- our local experience

 38 BCY Wong - 18 August, 2010

in 110th Anniversary scientific meeting, Faculty of Medicine, University of Hong Kong,

Hong Kong, October 1997.

8. Helicobacter pylori and its role for gastric cancer

in 5th Hong Kong International Cancer Congress, Hong Kong, November 1998.

9. Treatment of H. Pylori: New Regional data on Asia/Africa

In Region-Specific H. pylori Management Strategies Symposium
In Second International Workshop on Helicobacter pylori, April 1999, Hong Kong.

10. Current Management of Helicobacter pylori infection

Education and Training Center in Family Medicine, Department of Health, April 1999

11. Gastric cancer research in Changle, China.

National Helicobacter pylori research conference, Hainan, China, April, 1999.

12. Screening for colon and gastric cancer

Education and Training Center in Family Medicine, Department of Health, May 1999.

13. Carcinoma and lymphoma of stomach and intestine

Diploma in Gastroenterology Nursing, Hong Kong, June 1999.

14. Dyspepsia and intestinal metaplasia.

Hong Kong Medical Forum July, 1999, Hong Kong

15. Possible role of NSAID in gastric cancer chemoprevention

Inaugural Scientific Symposium of the Center of Alimentary Research and Education
(CARE), in conjunction with International Union of Pharmacology,
17-19th Sept 1999, Hong Kong.

16. Helicobacter pylori research in Fujian, China

The Sixth National Gastric Cancer Congress, China. 20 Sept 1999, Nanjing, China.

17. Apoptosis and chemoprevention of gastric cancer

6th Hong Kong International Cancer Congress, November, 1999, Hong Kong.

18. Cytokines, Eicosinoids and apoptosis of GI tumours

Asian Pacific Congress of Gastroenterology and Digestive Endoscopy, March 2000, Hong
Kong.

19. Stomach Cancer Intervention Study in Changle

Beijing International Workshop on Gastric Cancer and its Precursors, May 2000,

20. Chemoprevention of gastric cancer

Shanghai International Congress of Gastroenterology, August 2000, Shanghai, China.

21. Management of Helicobacter pylori infection

 39 BCY Wong - 18 August, 2010

Zhong Shan Hospital, Shanghai Medical University, August 2000, Shanghai, China

22. Portal enteropathy

Liver Diseases in the New Millennium, September 2000, Shanghai, China.

23. Helicobacter pylori infection

Zhejiang First Hospital, Zhejiang University Medical College, September, 2000, Hangzhou,
China.

24. Apoptosis and chemoprevention of gastric cancer

Zhejiang First Hospital, Zhejiang University Medical College, September, 2000, Hangzhou,
China.

25. Management of Helicobacter pylori infection- an Asian perspective

Scientific meeting, Beijing Branch of Chinese Medical Association, October 2000, Beijing,
China

26. Signal transduction in gastric cancer prevention

Beijing Medical University First Teaching Hospital, October 2000, Beijing, China

27. Apoptosis and chemoprevention of gastric cancer

Beijing Friendship Hospital, Capital University of Medical Sciences, October 2000, Beijing.

28. Management of Helicobacter pylori infection- an Asian perspective

Gastroenterology in the 21 st Century, Guangzhou branch of Chinese Medical Association,
Guangzhou, November 2000.

29. Chemoprevention of colorectal cancer

7th Hong Kong International Cancer Congress, December 2000, Hong Kong.

30. Cyclooxygenase-2 and protein kinase C signalling in gastric cancer

Molecular Genetic Basis of Cancer, Advanced Study Institute, The Croucher Foundation, 6-
12, January 2001, Hong Kong.

31. Cyclooxygenase signalling in prevention of gastric cancer

Shanghai Society of Gastroenterology, Shanghai, February 2, 2001.

32. Molecular genetics of gastric cancer

GI malignancies can be prevented and treated: from the bench to the bedside, February 14-
17, 2001, Israel.

33. The first intervention study to prevent gastric cancer by eradicating the bug
GI malignancies can be prevented and treated: from the bench to the bedside, February 14-
17, 2001, Israel.

34. GI toxicity of NSAIDs and new safety evidences of COX-2 specific inhibitors
 40 BCY Wong - 18 August, 2010

In CME Lecture series, HK Medical Association CME Program, February 22, 2001, Hong
Kong.

35. New approaches in Helicobacter pylori eradication

In scientific symposium: “Helicobacter pylori management in 21st century” of the Hong
Kong Society of Gastroenterology, Feb 24, 2001, Hong Kong.

36. Diet and Gastric cancer

Gastro 2001, Annual Scientific Meeting of the Malaysian Society of Gastroenterology
together with American Gastroenterological Association, April 5-8, 2001, Malaysia.

37. GI safety of NSAIDs and new COX-2 inhibitors

In CME program, Hong Kong Doctor’s Union, March 22, 2001, Hong Kong

38. Management of Helicobacter pylori

Symposium, Hong Kong Society of Endoscopy Nurses, April 21, 2001, Hong Kong.

39. Cyclooxygenase signaling in gastric cancer prevention

First Sino-European workshop on the immunogenetics and pathogenesis of gastric cancer,
April 26-28, 2001, Xian, China

40. Helicobacter pylori antibiotic trials

In symposium “ Prevention in the New Millenium” in
4th International Gastric Cancer Congress, April 29-May 2, 2001, New York, USA.

41. Prevention of gastric cancer: bench and bedside

Seminar, Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, USA
May 25, 2001.

42. Aspirin induced apoptosis in gastric cancer

Seminar, Department of Gastroenterology, Free University, Amsterdam, The Netherlands
June 1, 2001.

43. Management of Helicobacter pylori infection

The 11th Hong Kong Doctors Union Symposium on Gastroenterology and Hepatology,
Princess Margaret Hospital, June 24, 2001

44. GI toxicity of NSAIDs and new safety evidence of COX-2 specific inhibitors
CME symposium, The Association of Licentiates of Medical Council of Hong Kong,
HKHA headquarter, July 29, 2001.

45. Updated role of H. pylori in acid related diseases

Indochina conference, Update on GERD and H. pylori Management in Asia, Ho Chi Minh
City, Vietnam, August 10-13, 2001.

46. GI safety of NSAIDs and new COX-2 inhibitors

 41 BCY Wong - 18 August, 2010

In CME program, Hong Kong Doctor’s Union, September 13, 2001, Panda Hotel, Tsuen
Wan, Hong Kong.

47. NSAIDs and colorectal cancer biology

In symposium “Colorectal cancer: a disease of changing societies” in
Asian Pacific Digestive Week, 23-28 September 2001, Sydney, Australia.

48. Screening the average risk population for colorectal cancer

In breakfast session (meet the experts)
Asian Pacific Digestive Week, 23-28 September 2001, Sydney, Australia.

49. Latest development in the management of acid-related diseases

In CME program, Hong Kong Medical Association, October 16, 2001, Hong Kong

50. Management of Helicobacter pylori and NSAID-related GI problems.

In CME Program, Baptist Hospital, November 1, 2001.

51. Virtual colonoscopy,

In Fourth Annual Scientific meeting, Hong Kong Society for coloproctology, November 3,
2001, Hong Kong.

52. Management of H. pylori, the future direction

2nd Chinese Digestive Disease Week, Shanghai, 6-9 November, 2001, Shanghai.

53. Cyclooxygenase and gastric cancer

2nd Sino Japanese Symposium on digestive system tumours, December 2001, Guangzhou.

54. Current best medical treatment in Inflammatory bowel disease

Hong Kong Surgical Forum, 11-13 January, 2002.

55. Different approaches of incorporating TCM in treatment of gastrointestinal diseases

TWGHs-HKU Eddie Wang Chinese Medicine Symposium, Hong Kong, February 2-3,
2002Chemoprevention of gastric cancer

56. Gastric cancer symposium, Postgraduate Course, World Congress of Gastroenterology,

Bangkok, Thailand, February 2002.

57. Management of Acid related diseases

CME meeting, Quality HealthCare Medical Center Ltd, Hong Kong, 26 March, 2002.

58. Management of Helicobacter pylori infection

CME program, Hong Kong College of Family Physicians, Hong Kong, 10 May, 2002.

59. Cyclooxygenase-2 and gastric cancer

5th National Digestive Disease Conference, Guangzhou, China, 11-12 May, 2002.

60. Chemoprevention of gastric cancer

 42 BCY Wong - 18 August, 2010

Invited departmental talk, University of Arizona, Tucson, USA, 27 May, 2002

61. Targeting survivin in gastrointestinal cancers

Invited departmental talk, National Cancer Institute, Bethesda, USA, 23 May 2002

62. Differential approaches of incorporating traditional chinese medicine in the treatment of

gastrointestinal diseases
Symposium in Medical Sciences- 21st Century Health Care in Hong Kong, 1-2 June 2002,
Hong Kong.

63. Pathogenesis and prevention of gastric cancer

In 18th UICC International Cancer Congress, 30 June 2002, Oslo, Norway.

64. Endoscopic retrograde cholangio-pancreatography

In 7th Hong Kong Medical Forum, 6-7 July 2002, Hong Kong

65. Current management of Helicobacter pylori infection

In Third National Helicobacter pylori meeting, Chinese Society of Gastroenterology, 15
August, 2002, Beijing, PR China.

66. Update on diagnosis and management of Helicobacter pylori infection

Seminar, Hong Kong Medical Technologist Association, 24 September 2002.

67. Prevention of gastric cancer through eradication of Helicobacter pylori infection,

Special Symposium- The role of genetics, infection and diet in gastrointestinal tumours,
In 27th European Society for Medical Oncology meeting, 18 October, 2002, Nice, France.

68. Chemoprevention of gastric cancer

Keynote lecture, In Frontiers in Biomedical Research, HKU 2002, 6 December 2002,
Hong Kong.

69. Chemoprevention of GI malignancies.

In Symposium on New therapies for GI malignancy, 18th World Congress of Digestive
Surgery, 8-12 December 2002, Hong Kong.

70. Chemoprevention of GI malignancies.

In Symposium on New therapies for GI malignancy, 18th World Congress of Digestive
Surgery, 8-12 December 2002, Hong Kong.

71. Common Medical Conditions including emergency.

In Certificate Course for clinic nurses, The Federation of Medical Societies of Hong Kong,
26 February, 2003.

72. Role of COX-2 in oncology.

In Articulum: Second Asia Pacific advisory board program. March 6-8, 2003, Sydney,
Australia.
 43 BCY Wong - 18 August, 2010

73. Epidemiological Study of IBS in Hong Kong

In First Chinese National Conference of IBS, Chinese Society of Gastroenterology,
Guangzhou, 14-16 March 2003.

74. Updated management of acid-related diseases

The Society of Physicians of Hong Kong, July 8, 2003, Hong Kong.

75. Helicobacter pylori and gastric cancer,

In Grand Round, Columbia University College of Physicians and Surgeons, New York,
USA, July 2003

76. Signaling mechanisms of NSAID in chemoprevention of gastric cancer

In Columbia University College of Physicians and Surgeons, New York, USA, July 2003

77. Management of GERD

In CME program, St Teresa’s Hospital, August 12, 2003

78. Helicobacter pylori infection and gastric cancer

In First Military Medical University, Guangzhou, PR China, 12 September 2003

79. Constipation: Epidemiology and Investigations

In Symposium on Constipation, Organized by Guangdong Society of Gastroenterology and
Sun Yat Sen Medical University, Guangzhou, 13 September 2003

80. FOBT- immunochemical or guaiac

In Symposium “Colorectal cancer screening issues in Asia Pacific”, In Asia Pacific
Digestive Week 2003, Singapore, 28 September 2003

81. H. pylori eradication: does it prevent gastric cancer?

In Symposium “Helicobacter pylori”, In Asia Pacific Digestive Week 2003, Singapore, 29
September 2003

82. Chemoprevention of gastric cancer.

Invited by Oncology Research Institute, National University of Singapore and Institute of
Molecular and Cell Biology, Singapore, 30 September, 2003, Singapore

83. Helicobacter pylori – from diagnosis to treatment

Educational Programs, the Neuro-enteric clinical research group, University of Arizona, 30
October, 2003, Tucson, USA.

84. Update in Gastroesophageal reflux management

In Medical Education Program, Astrazeneca LP, 30 October 2003, Tucson, USA

85. Definition and Diagnosis of Gastro-esophageal reflux disease

In the second FAST expert meeting, Eisai, Fukuoka, Japan, 8 November 2003.

86. Management of Helicobacter pylori infection

 44 BCY Wong - 18 August, 2010

Seminar arranged by Shunde Health Bureau, China, 15 November 2003

87. Helicobacter pylori and gastric cancer,

In 2003 annual scientific symposium, Shanghai Society of Gastroenterology, Shanghai, 22
November 2003.

88. Review of chest pain studies with special focus on reflux disease.
In Chest pain management working group meeting, Astrazeneca, New York, USA, 8
December 2003.

89. Using Fecal occult blood test for screening in Chinese population.
Keynote lecture, In Annual Scientific meeting 2003, Hong Kong Society for coloproctology,
Hong Kong, 13 December 2003.

90. Helicobacter pylori and dyspepsia – to eradicate or not to eradicate

New Frontiers in GERD and dyspepsia, January 24-25, 2004, Arizona, USA

91. Updated management of Gastroesophageal reflux disease

Phillippine Society of Gastroenterology and Phillippine Society of Digestive Endoscopy
Joint Annual Convention 2004, Manila, Phillippines, March 9, 2004.

92. Non-ulcer dyspepsia – pH, Hp or 5-HTP

Phillippine Society of Gastroenterology and Phillippine Society of Digestive Endoscopy
Joint Annual Convention 2004, Manila, Phillippines, March 11, 2004.

93. The Latest Update on Helicobacter pylori management

Lunch Symposium, Abbott Laboratories, March 27, 2004, Tsimshatsui, Hong Kong.

94. Gastric cancer

Peking University First Hospital, Beijing, PR China, April 15, 2004.

95. Helicobacter pylori and gastric cancer

Gastroenterology Biannual Meeting, Shanghai Society of Gastroenterology, April 17, 2004,
Shanghai, PR China

96. The Latest Update on Helicobacter pylori management

Dinner Symposium, Abbott Laboratories, May 7, 2004, Tuen Mun, Hong Kong.

97. Managing Dyspepsia in regions with a high risk of gastric cancer

Transatlantic Pacific Summit, TAP Pharmaceutical Products, May 19-21, 2004, New
Orleans, USA.

98. GERD – is it rare in Asia?

AstraZeneca Headquarter, Molndal, Sweden, June 8, 2004

99. Gastric Cancer – past, present and future

First Beijing Digestive Disease Forum, Beijing, June 18, 2004
 45 BCY Wong - 18 August, 2010

100. Optimising the treatment approach to GERD

Lunch Symposium, Annual Scientific Meeting of Malaysian Society of Gastroenterology
and Hepatology, Penang, Malaysia, June 24, 2004.

101. Atypical manifestation of GERD

Annual Scientific Meeting of Malaysian Society of Gastroenterology and Hepatology,
Penang, Malaysia, June 24, 2004.

102. Refractory H.pylori infection- what would I do?

Meet the expert session, Annual Scientific Meeting of Malaysian Society of
Gastroenterology and Hepatology, Penang, Malaysia, June 24, 2004.

103. Screening and surveillance of colorectal cancer

Annual Scientific Meeting of Malaysian Society of Gastroenterology and Hepatology,
Penang, Malaysia, June 24, 2004.

104. Update on medical management of inflammatory bowel diseases.

Hong Kong Surgical Forum, July 10, 2004.

105. Helicobacter pylori infection – to treat everyone?

9th Hong Kong Medical Forum, Department of Medicine, University of Hong Kong, July 18,
2004.

106. Helicobacter pylori and gastric cancer

Medical Forum China, Fourth Medical Military University, Xian, China, July 20, 2004.

107. Controversies in Helicobacter pylori infection

First Guangdong Gastroenterology Meeting, Guangzhou, July 30, 2004. [Keynote lecture]

108. Management of resistant Helicobacter pylori infection

Joint Thailand and Myanmar Gastroenterology Meeting, Myanmar, August 1, 2004.

109. Helicobacter pylori and gastric cancer- the final story?

Alimentary Disease Weekend, University of Hong Kong, Hong Kong, Sept 19, 2004.

110. FAST survey on NCCP

In the Third FAST expert panel meeting, Hong Kong, 20 September 2004.

111. Functional dyspepsia – pH, Hp or more?

Asia Pacific Digestive Week, Beijing, PR China, October 5, 2004.

112. Chemoprevention of colorectal cancer.

Asia Pacific Digestive Week, Beijing, PR China, October 5, 2004.

113. Validating RDQ in the diagnosis of GERD.

GI Summit, Astrazeneca, Beijing, PR China, October 3, 2004
 46 BCY Wong - 18 August, 2010

114. Wireless pH monitoring: its technology and application

GI Summit, Astrazeneca, Beijing, PR China, October 3, 2004

115. Randomized controlled trials.

In APAGE/OMGE training workshop on clinical research methods
Post-graduate course, Asia Pacific Digestive Week, Beijing, PR China, October 4, 2004.

116. H pylori and GU/PU healing: new treatment options

Astrazeneca symposium on Nexium: maximize clinical benefits.
Asia Pacific Digestive Week, Beijing, PR China, October 5, 2004.

117. Prevention of gastric cancer

5th Joint Annual Scientific Meeting, Hong Kong Society of Gastroenterology, Hong Kong,
October 9, 2004.

118. Diagnosis and Management of resistant Helicobacter pylori infection

62nd Hong Kong Doctors Union Sunday Symposium, October 17, 2004.

119. Targeting COX-2 in prevention and treatment of GI cancers.

Genomics, Proteomics and Therapeutics in Cancer Research, Faculty of Medicine,
University of Hong Kong, Hong Kong, October 20-21, 2004

120. Colorectal and gastric cancer screening in Hong Kong.

International Conference of Cancer Screening in Asia, Keelong, Taiwan, Oct 26, 2004

121. Intervention Studies of gastric cancer

5th Western Pacific Helicobacter pylori congress, Japan, November 18, 2004.

122. Helicobacter pylori and gastric cancer

3rd Digestive Disease Seminar, Hyogo College of Medicine, Hyogo, Japan, Nov 18,
2004.

123. Helicobacter pylori and gastric cancer

In: Caritus Medical Center 40th Anniversary Scientific Symposium, Hong Kong, Nov 20,
2004

124. Targeting Inhibitors of apoptosis in cancer treatment

Frontiers in biomedical research, Faculty of Medicine HKU Dec 3-4, 2004

125. First, second and third line treatment of Helicobacter pylori infection, and capsule
endoscopy
Annual refresher course, Hong Kong College of Family Physicians, Dec 10, 2004.

126. Common gastrointestinal diseases

Luncheon meeting, Lions Club of Victoria Hong Kong, January 12, 2005.
 47 BCY Wong - 18 August, 2010

127. Targeting the inhibitor of apoptosis proteins in cancer treatment

The Croucher Advanced Study Institute “Molecular genetics and cell signalling in cancers”
January 17-21, 2005.

128. From aspirin to apoptosis: Prevention and treatment of GI cancers

Peking University First Hospital, Beijing, PR China, 10 March 2005.

129. Diet and GI diseases,

Digestive Health Awareness Coalition Program for the Family Planning Association of
HK (FPA), FPA auditorium, Wanchai, Hong Kong, 22 April, 2005.

130. GERD: Defining the standards of management.

Symposium of Hong Kong Society of Gastroenterology and Hong Kong Society of
Digestive Endoscopy, Hong Kong. 25 April, 2005.

131. Intervention study on Helicobacter pylori and gastric cancer

6th International Gastric Cancer Congress, Yokohama, Japan, 5 May 2005.

132. Guaiac vs. I-FOBTs screening experience

OMED colorectal cancer screening meeting, Chicago, USA, 15 May, 2005.

133. Gastric cancer

Meet-the-Professor Luncheon, Digestive Disease Week, Chicago, USA, 18 May 2005.

134. Recent advances in screening and treatment of colon cancer for primary care physicians
Hong Kong College of Family Physicians meeting, Hong Kong, 29 June 2005.

135. Common Gastrointestinal diseases.

Seminar, Chinese General Chamber of Commerce, 4 July 2005.

136. Eradication of Helicobacter pylori to prevent gastric cancer

In International Gastroenterology Conference, Shanghai, China, 8 July 2005.

137. Targeted therapies for gastrointestinal cancers

In 10th Medical Forum, Department of Medicine, University of Hong Kong, 17 July 2005.

138. Peptic Ulcer & Helicobacter pylori Infection

Digestive Health Awareness Coalition Program, Hong Kong Digestive Foundation, for
the Family Planning Association of HK (FPA), FPA auditorium, Wanchai, Hong Kong,
9 September, 2005.

139. Epidemiology of Reflux Disease

Astrazeneca symposium “The leading edge of reflux disease”, World Congress of
Gastroenterology, Montreal Canada, 12 September, 2005.

140. Can we prevent gastric cancer

 48 BCY Wong - 18 August, 2010

In symposium “H pylori, gastritis and gastric cancer”, World Congress of

Gastroenterology, Montreal Canada, 12 September, 2005.

141. Perspectives of gastric cancer from Asia.

In Canadian Helicobacter Study Group post-WCOG meeting, Montreal, Canada, 15
September, 2005.

142. Chemoprevention of gastric cancer by eradication of H .pylori infection

In 2005 Taipei Forum of Gastroenterology, Taipei, Taiwan, 1 October 2005

143. Diet and GI diseases,

Digestive Health Awareness Coalition Program for the Family Planning Association of
HK (FPA), Sheung Shui Women Club of FPA, 4 October, 2005.

144. Helicobacter pylori Infection and peptic ulcers

Ma On Shan District Elderly Community Centre, Kam Tai Court, Ma On Shan, 14
October 2005.

145. Common gastrointestinal diseses

Luncheon symposium, Rotary Club of the Peak, China Club, Hong Kong, 1 Nov 2005.

146. Common gastrointestinal diseses

Luncheon symposium, City Lions Club of Hong Kong, Conrad Hotel, Hong Kong, 8
November, 2005.

147. Difficulties in colon cancer screening in Hong Kong.

Second International Asian Conference of Cancer Screening, Taipei, Taiwan, 22 November
2005.

148. PPI Failure/ Resistance – Mechanisms & Solutions.

In 4th FAST expert panel meeting, Eisai Co Ltd, Bangkok, Thailand, 26 Nov 2005.

149. Common gastrointestinal diseses

Luncheon symposium, Lions Club of Hong Kong East, Miramar Hotel, Hong Kong, 2
December, 2005.

150. Prevention of Digestive Cancers: Kill the bug or take the drug
Annual General Meeting of Hong Kong Pharmacology Society, 8 December 2005.

151. New Imaging Technique for colon cancer screening

12th Hong Kong International Cancer Congress, Hong Kong, December 9, 2005.

152. Double Balloon Enteroscopy.

CME program at St Teresa’s Hospital, Hong Kong, December 11, 2005

153. Common gastrointestinal diseses

 49 BCY Wong - 18 August, 2010

Lunch symposium, Hong Kong Oriental Lions Club meeting, Grand Hyatt Hotel, Hong
Kong, 10 January, 2006.

154. Stress and gastrointestinal diseses

Dinner symposium, Lions Club of Hong Kong Zone 10 joint meeting, Miramar Hotel, Hong
Kong, 10 January, 2006.

155. Use of intravenous proton pump inhibitor in acid related diseases

Round Table Discussion, Tan Tock Seng Hospital, Singapore, 25 February, 2006.

156. Prevention of NSAID gastropathy.

GIHep Singapore 2006, Singapore 26 February, 2006.

157. Non cardiac chest pain.

Functional GI Research Forum, GIHep Singapore 2006, Singapore 26 February, 2006.

158. Common GI diseases

Joint dinner meeting of Lions Club of Hong Kong (Host), Lions Club of Kwun Tong,
Lions Club of Hong Kong Island, Lions Club of Silverstrand, Lions Club of Red Hill,
and Lions Club of Pearl Harbour, Conrad Hotel, 17 March 2006.

159. Diet and GI diseases

Digestive Health Awareness Coalition Program for the Family Planning Association of
HK (FPA), Ma On Shan, Hong Kong, 1 April, 2006.

160. Update on screening and treatment of colon cancer.

CME program at St Teresa’s Hospital, Hong Kong, April 2, 2006.

161. Randomized trials in China, in Symposium: Prevention of Gastric Cancer by Eradication

of Helicobacter pylori, in 92nd Annual scientific meeting of Japanese Society of
Gastroenterology, Kikura, Japan, 20 April 2006.

162. Does Helicobacter pylori eradication prevents gastric cancer.

The 15th Porto Cancer Meeting, Porto, Portugal, 27 April 2006.

163. Diagnosis and Management of liver diseases.

Dinner talk at Chinese General Chamber of Commerce, 9 May 2006.

164. GERD in Asia

3rd Beijing International Digestive Disease Forum, PR China, 27 May 2006

165. Dyspepsia is not a universal diagnosis for patients with epigastric pain
11th Hong Kong Medical Forum, Convention Center, Hong Kong, 3 June 2006.

166. Dyspepsia is not a universal diagnosis for patients with epigastric pain
11th Hong Kong-China Medical Forum, Guangzhou, PR China, 6 June 2006.
 50 BCY Wong - 18 August, 2010

167. Gastro-esophageal reflux diseases: Impact on quality of life

5th FAST expert panel meeting, Tokyo, Japan, 10 June 2006.

168. Chemoprevention of Gastric cancer by aspirin; bench to bedside

4th International Society of Gastroenterological Carcinogenesis Conference, Hawaii, 24-26,
August 2006.

169. What is the prevalence of GERD in far East countries? In Plenary Session 5:
Pathophysiology and Controversies in GERD, in the 8th World Congress, World
Organization for Specialized Studies on Diseases of the Esophagus, Avignon, France, 3-6
September, 2006.

170. Why is the incidence of adenocarcinoma of the esophagus and gastric cardia increasing?
In Plenary Session 6: 8th World Congress, World Organization for Specialized Studies on
Diseases of the Esophagus, Avignon, France, 3-6 September, 2006.

171. Montreal definition of GERD.

AstraZeneca Lunch Symposium, Ritz Carlton Hotel, Hong Kong, 14 September 2006.

172. Montreal definition of GERD.

AstraZeneca Lunch Symposium, Langham Hotel, Hong Kong, 21 September 2006.

173. Use of COX inhibitors in prevention of gastric cancer

3rd annual conference, Organisation for Oncology and Translational Research, September
22-23, 2006, Hong Kong,

174. GERD.
Symposium, Hong Kong College of Family Physicians, Hong Kong, 15 October 2006.

175. Helicobacter pylori and gastric cancer

Sino Japan International Conference on early gastrointestinal cancer, 9-11 November, 2006,
Shanghai, PR China.

176. Which FOBT?

3rd International Asian Conference on Cancer Screening, 17 November 2006, Singapore.

177. Digestive and Liver Diseases.

Dinner meeting, Worldwide Chinese Investors Association International Limited, Hong
Kong, 20 November 2006.

178. PPI refractory GERD.

Breakfast with the Champions section, Asia Pacific Digestive Week 2006, Philippines, 26-
29 November 2006.

179. Diagnosis of GERD, is clinical profile enough?

Asia Pacific Digestive Week 2006, Philippines, 26-29 November 2006.
 51 BCY Wong - 18 August, 2010

180. Update on treatment of peptic ulcers

AstraZeneca lunch symposium, Asia Pacific Digestive Week 2006, Philippines, 26-29
November 2006.

181. Chemoprevention of Gastric cancer by aspirin; bench to bedside

Keynote lecture: Frontiers in Biomedical Research HKU 2006. 8 December 2006, Faculty
of Medicine, University of Hong Kong, Hong Kong.

182. Does Helicobacter pylori eradication prevent gastric cancer

Sun Yat Sen Medical University, Guangzhou, PR China, 25 December 2006.

183. Management of Barrett’s esophagus and high grade dysplasia.

GIHep Singapore 2007, Singapore, 3 March 2007.

184. Common liver diseases

Dinner talk to Kowloon Liaison Office, Chinese General Chamber of Commerce, 12 April
2007.

185. Prevention of colon cancer

Hong Kong Federation of Women Health Talk Series, HA headquarter, 28 April 2007.

186. Does Helicobacter pylori eradication prevent gastric cancer

7th National Digestive Disease Week, Jinan, Shandong, PR China, 7th May 2007.

187. Common gastrointestinal and liver diseases

Dinner talk to Youth Committee, Chinese General Chamber of Commerce, 3 May 2007.

188. GERD
Xiamen University Zhong Shan Hospital, Xiamen, PR China, 12 May, 2007.

189. Targeting apoptosis in GI cancers: Aspirin and beyond.

National Cancer Institute, USA. 22 May, 2007.

190. H. pylori treatment and related chemoprevention of gastric cancer in elderly.

In: Symposium of Cancer Prevention in the Elderly. In Digestive Disease Week,
Washington DC, USA, 23 May 2007.

191. Common Gastrointestinal Diseases

Hong Kong Commerce and Industry Association dinner talk, 14 June 2007.

192. Update on diagnosis and management of GERD

4th Beijing International Digestive Disease Forum, Beijing, China, 15 June 2007.

193. Eradication of H pylori, is it necessary for gastric cancer prevention?

13th Annual meeting of Japanese Society for Hp research, Shiga, Japan, 21 June 2007.

194. Update of the management of GERD

 52 BCY Wong - 18 August, 2010

Astrazeneca Symposium, Hanoi, Vietnam, 29 June 2007.

195. Update of the management of GERD

Astrazeneca Symposium, Ho Chi Minh City, Vietnam, 30 June 2007.

196. The Evidence Base Medicine for use of PPI in patients with functional dyspepsia
Eisai Symposium, Ho Chi Minh City, Vietname, 11 July 2007.

197. The Evidence Base Medicine for use of PPI in patients with functional dyspepsia
Thailand Association of Gastroenterology meeting, Hua Hin, Thailand, 13 July 2007.

198. Colon cancer screening.

2nd Guangdong Digestive Disease Week, Guangzhou, PR China, 17 August 2007.

199. Advance in Helicobacter pylori research

Endoscopy Festival on Gastroenterology Beijing 2007 and 9th Digestive Endoscopy
Conference of Chinese PLA General Hospital, Beijing, 31 August 2007.

200. Human intervention trials on Helicobacter pylori and gastric cancer.

66th Annual Meeting of Japanese Cancer Association, Yokohama, Japan, 4 October 2007.

201. Stomach cancer: molecular targets for prevention and treatment

Keystone Symposium on Frontiers in Gastrointestinal Cancer: Molecular Genetics,
Inflammation, Early Detection and Therapy, October 14 - 19, 2007, Beijing, China.

202. Helicobacter pylori and gastric cancer.

Asia Pacific Digestive Week 2007, Kobe, Japan, 16 October 2007.

203. GERD in China

Asia Pacific Digestive Week 2007, Kobe, Japan, 16 October 2007.

204. Targeted therapy in gastrointestinal cancers

Annual scientific meeting of The Federation of Medical Societies of Hong Kong, Hong
Kong, 20 October 2007.

205. Eradication of H. pylori for gastric cancer prevention

Cross-Straits Digestive Forum, Xiamen, PR China, 17 November 2007.

206. H. pylori eradication in the prevention of gastric cancer

Sixth Annual AACR international Conference: Frontiers in Cancer Prevention Research,
Philadelphia, USA, 5-8 December 2007.

207. Prevention of stomach and colon cancer

Luncheon talk, Zonta Club of Hong Kong East, Hong Kong, 13 December 2007.

208. Molecular targets of GI cancer

Frontiers in Biomedical Research, HKU 2007, 13 December 2007.
 53 BCY Wong - 18 August, 2010

209. H. pylori eradication in the prevention of gastric cancer

Fourth Military Medical University, Xian, 21 March 2008.

210. The role of Helicobater pylori eradication in the prevention of gastric cancer
In Symposium: New Concepts in Gastric Cancer, In Annual Meeting of the American
Association for Cancer Research 2008, 12-16 April 2008.

211. Influenza
HHCKLA Buddhist Ma Kam Chan Memorial English Secondary School, 7 May 2008.

212. Emerging Issues in management of acid related diseases

Astrazeneca Symposium, Queen Mary Hospital, Hong Kong, 31 May 2008.

213. The spectrum of GERD: chest pain or more.

Grand Round, Dept of Medicine, Princess Margaret Hospital, Hong Kong, 11 June 2008.

214. Capsule endoscopy and double balloon enteroscopy

Macau International Surgical Forum 2008, Macau, 14 June 2008.

215. Treatment of Helicobacter pylori for Prevention of gastric cancer

UCLA visiting professor program lecture, UCLA, USA, 26 June 2008,

216. Chemoprevention of gastric cancer with aspirin: from bench to bedside

UCLA visiting professor program lecture, UCLA, USA, 27 June 2008,

217. Treatment of Helicobacter pylori for Prevention of gastric cancer

Division of Gastroenterology, University of British Columbia, Canada, 3 Jul 2008.

218. Chemoprevention of GI malignancies

Division of Gastroenterology, University of British Columbia, Canada, 3 Jul 2008.

219. Latest data on incidence of GERD in Asia and trend over time
Asia Pacific GI Summit, Seoul, S Korea, 27 July 2008.

220. Management of GERD and NERD

Asia Pacific GI Summit, Seoul, S Korea, 27 July 2008.

221. GERD.
Lions Club of Central and HK Health Check & Lab Health Talk Series. 3 Sept 2008.

222. How do clinicians do science.

Eighth Chinese National Conference of Gastroenterology, Xian, China, October 12, 2008,

223. H Pylori eradication in the prevention of gastric cancer.

Eighth International conference of anticancer research, Kos, Greece, October 17-22, 2008.
 54 BCY Wong - 18 August, 2010

224. H Pylori eradication in the prevention of gastric cancer.

Shanghai Jiaotong University Renji Hospital, PR China, November 25, 2008.

225. Common GI diseases

Symposium, American Insurance Group, Hong Kong, December 3, 2008.

226. Helicobacter Pylori – What should we learn from the ACG guidelines
GI motility, functional bowel disorders and more, Phoenix, Arizona, USA, December 6,
2008.

227. Screening and prevention of gastric cancer.

2009 Gastrointestinal Cancer Symposium, San Francisco, USA, January 15, 2009.

228. New trials and chemoprevention of colon cancer in Asia, Fifth Annual Conference of the
Organization for Oncology and Translational Research meeting ,Macau, 20-21 February
2009.

229. Eradication of Hp for prevention of gastric cancer.

Guangdong General Hospital, Guangzhou, PR China, 24 February , 2009

230. Screening and prevention of cancer

Luncheon talk, Chinese General Chamber of Commerce, Hong Kong, 18 March 2009.

231. Eradication of Hp for prevention of gastric cancer.

Shanghai Fudan University School of Medicine, Zhong Shan Hospital, 9 April 2009.

232. Gastro-esophageal reflux diseases

Shanghai Fudan University School of Medicine, Zhong Shan Hospital, 9 April 2009.

233. Overview of Helicobacter pylori management.

Hong Kong Beijing Hangzhou Medical Forum 2009, Hangzhou 11 April, 2009.

234. Eradication of H Pylori to prevent gastric cancer, what else do we need?

IDCA/WGO business meeting, Digestive Disease Week, Chicago, 31 May, 2009.

235. Gastroesophageal Cancer in Asia: Endogenous and Environmental Factors. In

Symposium: The Changing Face of Gastrointestinal Cancer: A Worldwide Perspective.
Digestive Disease Week, Chicago, 31 May, 2009.

236. Asian Perspective. In Symposium: Optimal Therapies for H. pylori in a Changing

Environment: A Global Perspective.
Digestive Disease Week, Chicago, 2 June, 2009

237. Updated management of Helicobacter pylori infection

CME program, St Teresa’s Hospital, Hong Kong, 7 Jun 2009.

238. Overview of Helicobacter pylori management.

 55 BCY Wong - 18 August, 2010

6th Beijing International Digestive Disease Forum, Beijing, 12-14 June, 2009.

239. How do clinical physicians do science

2009 Southern Digestive Disease Forum and 5th National Academic Congress on Intestinal
Diseases. Guangzhou, 19-21 Jun, 2009.

240. Treatment of H pylori in prevention of gastric cancer

6th Shanghai International Conference of Gastroenterology, Shanghai, 1-4 July, 2009

241. Helicobacter pylori and gastric cancer

2nd Cross Strait Digestive Forum, Xiamen, China, 27-29 Aug, 2009.

242. Gastro-esophageal Reflux Disease

Astra-zeneca Scientific Symposium, Hong Kong, 5 Sept 2009.

243. Refractory GERD

11th Joint Annual Scientific Meeting of HK Society of Gastroenterology, HK Society of
Digestive Endoscopy, HK Society for Coloproctology, HK Association for the Study of
Liver Diseases, and HK Society of Gastrointestinal Motility, Hong Kong, 5 Sept 2009.

244. Screening and prevention of cancer

Medical Lecture: HKU School of Professional and Continued Education, 15 Sept 2009.

245. An overview of IBS Management

166th Hong Kong Doctors Union Sunday Afternoon Symposium, 20 Sept 2009.

246. Screening and prevention of cancer

Luncheon talk, Zonta Club of Hong Kong, 24 Sept 2009.

247. Eradication of H pylori to prevent gastric cancer: feasibility and effectiveness

Asia Pacific Digestive Week 2009, Taipei, Taiwan, 27-30 Sept 2009.

248. Prevention of gastric cancer: a global challenge

Sir David Todd Lecture,
Annual Scientific Meeting, Hong Kong College of Physicians, 11 October, 2009.

249. Prevention of stomach and colon cancer

Public Lecture Series 2, of the LKS Faculty of Medicine, University of Hong Kong, Central
Libruary, Hong Kong, 14 Nov 2009.

250. Tips to help you publish your research in high end GI journal
In: Third Taiwan GI Emerging Leader Program, Kaohsiung, Taiwan 15 Nov, 2009

251. Latest advance in Helicobacter pylori and GERD

Astrazeneca Scientific symposium, Taipei, Taiwan, 15 Nov 2009.

252. COX-2 inhibitor in clinical practice

 56 BCY Wong - 18 August, 2010

In” Educator’s meeting on COX-2 inhibitors: clinical updates on GI outcomes, Shanghai

China, 21 Nov 2009.

253. Review in Gastroenterology 2009

53rd anniversary scientific program, The Society of Physicians of Hong Kong, Hong Kong,
13 Dec 2009.

254. Latest advance in Helicobacter pylori

Chinese PLA General Hospital, Beijing, China, 25 Jan 2010.

255. Prevention of NSAID gastropathy

Symposium, Hong Kong, 23 March 2010.

256. Helicobacter pylori and gastric cancer

Health and Beauty Carnival, Lions Club of the Peak, Hong Kong, 28 March 2010.

257. Epidemiological biomarkers of gastric cancer

In Research Symposium: H. Pylori and other risk factors for gastric cancer, Digestive
Disease Week 2010, New Orleans, USA, 3 May, 2010.

258. Gastro-esophageal reflux disease

Health Talk organized by Health Action Magazine, Hong Kong, 15 May, 2010.

259. Epidemiology, screening and prevention of colorectal cancer

Multi-disciplinary management for colorectal cancer symposium 2010, Hong Kong, 22
May 2010.

260. Common gastrointestinal diseases

Dinner symposium, World Chinese Investors Association, Hong Kong, 29 Jun 2010.

261. Etiology and Prevention of gastrointestinal diseases

Health talk organized by Eastern District Council, Hong Kong, 10 Jul 2010.

10. SESSION CHAIRPERSONS IN CONFERENCES

1. Microbes and the community (symposium),
in 110th Anniversary Scientific Congress, Faculty of Medicine, University of Hong Kong,
Hong Kong, Oct 1997.
2. Colorectal Cancer (free paper session),
in 14th Asia Pacific Cancer Conference, Hong Kong, Nov 1997.
3. Helicobacter pylori and peptic ulcer disease(symposium)
in the 2nd Western Pacific Helicobacter Congress, Malaysia, June 1998.
4. Helicobacter pylori (free paper session)
in the 2nd Western Pacific Helicobacter Congress, Malaysia, June 1998.
5. Colorectal cancer symposium,
in 5th Hong Kong International Cancer Congress, Hong Kong, November 1998.
6. Early gastric cancer symposium,
 57 BCY Wong - 18 August, 2010

in Alimentary Disease Week, Philippines, November 1998.

7. Free paper session,
In 11th Asian Pacific Congress of Gastroenterology, Hong Kong, March 2000.
8. H. pylori: past, present and future,
In 11th Asian Pacific Congress of Gastroenterology, Hong Kong, March 2000.
9. Gastroenterology in the New Millennium,
In 11th Asian Pacific Congress of Gastroenterology, Hong Kong, March 2000.
10. H. pylori, cyclooxygenase and gastro-duodenal diseases,
In 2000 Shanghai International Conference of Gastroenterology, August 2000.
11. Plenary Session,
In Gastroenterology in the 21 st Century, Guangzhou branch of Chinese Medical
Association, Guangzhou, November 2000.
12. Gastric & Head and Neck symposium,
In 7th Hong Kong International Cancer Congress, December, 2000, Hong Kong.
13. Colorectal Cancer symposium,
In 2nd Annual Scientific Symposium of Center of Alimentary Research and Education,
December, 2000, Hong Kong.
14. COX-2 specific inhibitors: an update
Scientific lecture, Pharmacia/ pfizer, 12 January 2001, Hong Kong.
15. Second Joint Dutch-Hong Kong Gastroenterology Meeting
April 23, 2001, Hong Kong.
16. Colorectal cancer : The environment- risks and opportunities “chemopreventive agents”
In 6th Hong Kong Medical Forum, Department of Medicine, University of Hong Kong, July
7-8, 2001, Hong Kong.
17. Gastric cancer
In 18th UICC International Cancer Congress, 30 June 2002, Oslo, Norway.
18. Update on acid reflux
In 7th Hong Kong Medical Forum, 6-7 July 2002, Hong Kong
19. Colorectal cancer interactive session,
In 10th Hong Kong International Cancer Congress, 21 November 2003, Hong Kong.
20. Clinical symposium in Cancer
In 9th Medical Research Conference, University of Hong Kong, 7 February 2004.
21. Cancer and Chinese Medicine
In 9th Research Postgraduate Symposium, University of Hong Kong, 4 December, 2004.
22. Research Forum
In 7th Annual Scientific Meeting, HKSGE, Hong Kong, August 27, 2005
23. Practical therapeutics
In World Congress of Gastroenterology 2005, Montreal, Canada, 12 September 2005
24. Erbitux – best integration into current treatment options in mCRC. Prof Tim Maughan,
October 13, 2005, Mandarin Oriental Hotel, Hong Kong.
25. Colon cancer screening in Asia,
In 2nd International Asian Conference on Cancer Screening, Taipei, 22 November 2005.
26. Inflammatory bowel disease symposium,
In 3rd Beijing International Digestive Disease Forum, PR China, 27 May 2006.
27. Gastroenterology & Geriatrics symposium,
In 11th Hong Kong Medical Forum, Convention Center, Hong Kong, 3 June 2006.
28. Inflammation and Cancer
 58 BCY Wong - 18 August, 2010

In 4th International Society of Gastroenterological Carcinogenesis Conference, Hawaii, 24-

26, August 2006.
29. GERD in Asia
In Asian Pacific Digestive Week 2007, Kobe, Japan, 18 October 2007.
30. Digestive Diseases
In Cross-Straits Digestive Forum, Xiamen, PR China, 17 November 2007.
31. ERCP
In Digestive Endoscopy Workshop, HKU, Hong Kong, 1 December, 2007.
32. Symposium: New Concepts in Gastric Cancer,
In Annual Meeting, American Association for Cancer Research 2008, 12-16 April 2008.
33. Session on NERD and GERD: management and impact
In Asia Pacific GI Summit, Seoul, S Korea, 27 July 2008.
34. Session on Management strategies for gastric cancer and peptic ulcer diseases
In Asia Pacific GI Summit, Seoul, S Korea, 27 July 2008.
35. Session on molecular mechanism of multidrug resistance in gastric cancer
In 6th Shanghai International Conference of Gastroenterology, Shanghai, 1-4 July, 2009
36. Scientific symposium on chronic complications of PPIs
HKSGE and Eisai dinner symposium, Hong Kong, 10 August 2009.
37. Scientific symposium: H pylori and gastric cancer
Asia Pacific Digestive Week 2009, Taipei, Taiwan, 27-30 Sept 2009.
38. Annual Scientific Meeting of Hong Kong Society of Gastroenterology, Hong Kong, 11March,
2010.

11. ORGANIZER OF PROFESSIONAL MEETINGS

1. Member, Organising Committee, The Third International Conference of Gastroenterology,
Hong Kong & Shanghai, November 1995.
2. Member, Organising Committee, Alimentary Disease Week, Hong Kong, Dec 1997.
3. Member, Scientific Committee, 5th Hong Kong International Cancer Congress, Hong
Kong. November 1998
4. Member, Scientific Committee, 6th Hong Kong International Cancer Congress, Hong
Kong. November 1999
5. Secretary General, Organising Committee, Inaugural Scientific Symposium of the Centre of
Alimentary Research and Education and Controversies in Gastrointestinal
Pharmacology of International Union of Pharmacology (IUPHAR)., Hong Kong, September,
1999.
6. Member, Organising Committee, Asian Pacific Congress of Gastroenterology and
Digestive Endoscopy, Hong Kong. March 2000.
7. Member, Organising Committee, Fourth Shanghai International Symposium on Liver
Cancer and Hepatitis & Second Scientific Meeting of Cheng Si-yuan Hepatitis Research
Foundation. September 2000, Shanghai, China.
8. Secretary General, Organising Committee, Second Scientific Symposium of the Centre of
Alimentary Research and Education, December, 2000, Hong Kong.
9. Chairman, Organising Committee, Scientific symposium, Dutch Society of
Gastroenterology meets the Hong Kong Society of Gastroenterology, 2001.
April 23, 2001, Hong Kong.
10. Secretary, APDW Postgraduate Course, World Congress of Gastroenterology, February
 59 BCY Wong - 18 August, 2010

2002, Bangkok, Thailand.

11. Vice Chairman, Scientific Committee, 3rd National Helicobacter pylori conference, August
2002, Beijing, PR China.
12. Member, Program Committee, World Congress of the International Society of Digestive
Surgery, Hong Kong, December 2002.
13. Member, Organising committee, 9th Hong Kong International Cancer Congress, December
2002.
14. Member, Organizing committee, 10th Hong Kong International Cancer Congress,
November 2003
15. Chief organizer, symposium on colorectal cancer, 10th Hong Kong International Cancer
Congress, November, 2003
16. Chief organizer, symposium on gastric cancer, 10th Hong Kong International Cancer
Congress, November, 2003
17. Scientific Committee, Second AACR International Conference on “Frontiers in Cancer
Prevention Research.” October 26-30 2003, Phoenix, Arizona.
18. Member, Scientific committee, 10th Hong Kong International Cancer Congress,
November 2003
19. Member, Organising committee, Hong Kong Shanghai International Liver Congress,
February 2004.
20. Member, Scientific committee, First Beijing Digestive Disease Forum, June 17-20, 2004,
Beijing, China.
21. Chairman, Organising committee, 9th Hong Kong Medical Forum, Department of Medicine,
University of Hong Kong, July 17-18, 2004, Hong Kong.
22. Chairman, Alimentary Disease Weekend, Department of Medicine and Surgery, University
of Hong Kong, September 18-19, 2004, Hong Kong.
23. Chairman, Third FAST expert panel meeting, 20 September, 2004, Hong Kong.
24. Member, Organizing committee, 11th Hong Kong International Cancer Congress,
10-12 November 2004.
25. Vice Chairman, Scientific committee, 11th Hong Kong International Cancer Congress, 10-
12 November 2004.
26. Member, Organizing committee, Frontiers in Biomedical Research, University of Hong Kong,
3 December, 2004
27. Vice Chairman, Scientific committee, 12th Hong Kong International Cancer Congress, 8-10
December 2005.
28. Member, Organizing committee, 12th Hong Kong International Cancer Congress,
8-10 December 2005.
29. Member, Organizing committee, Frontiers in Biomedical Research, University of Hong Kong,
2 December, 2005.
30. Member, Scientific committee, International Symposium on cancer prevention and early
detection. Beijing, PR China, April 21, 2006
31. Advisor, Sino-Japan International Conference on early gastrointestinal cancer, 9-11
November 2006, Shanghai, PR China
32. Vice Chairman, Scientific committee, 13th Hong Kong International Cancer Congress, 15-17
November 2006.
33. Member, Organizing committee, 13th Hong Kong International Cancer Congress,
15-17 November 2006.
34. Central Committee, 3rd International Asian Conference on Cancer Screening, 17-18 Nov 2006.
 60 BCY Wong - 18 August, 2010

35. Chairman, Scientific committee, 14th Hong Kong International Cancer Congress, 14-17
November 2007.
36. Member, Organizing committee, 14th Hong Kong International Cancer Congress,
14-17 November 2007.
37. Member, Scientific committee, Fourth Beijing Digestive Disease Forum, June 17-20, 2007,
Beijing, China.
38. Chairman, Scientific committee, 14th Hong Kong International Cancer Congress, 14-17
November 2007.
39. Member, Organizing committee, 14th Hong Kong International Cancer Congress,
14-17 November 2007.
40. Chairman, Cross-Straits Digestive Forum, Xiamen, PR China, 17 November 2007.
41. Honorary Advisor, Digestive Endoscopy Workshop, HKU, 1-2 December 2007.
42. Member, Scientific committee, Fifth Beijing Digestive Disease Forum, June 17-20, 2008,
Beijing, China.
43. Co-chairman, Scientific Program Committee, Seventh Annual Frontiers in Cancer
Prevention Research Conference, American Association for Cancer Research,
Washington DC, USA, 16-19 November 2008.
44. Program Committee, Joint AGA, ASCO, ASTRO 2009 Gastrointestinal Cancers Symposium,
San Francisco, USA, 15-17 January 2009
45. Education Committee, 2009 Annual American Association for Cancer Research Meeting,
Denver, CO, April 18-22, 2009.
46. Chairman, 2nd Cross Strait Digestive Forum, Xiamen, China, 27-29 Aug, 2009.

12. PROFESSIONAL ORGANISATIONS

Intermational:
1. Committee member, OMGE (World Gastroenterology Organisation) working group on
role of Gastroenterologist in management of GI cancer patients. 1999-
Chairman – Professor Sidney Winawer, USA
2. Committee member, International Liaison committee, Asian Pacific Association of
Gastroenterology. 2001-
3. Committee member, OMGE (World Gastroenterology Organisation) subcommittee on
development of digestive cancers. 2001-
Chairman – Professor Sidney Winawer, USA
4. Committte member, OMED (World Organisation of Digestive Endoscopy) Asia Pacific
subcommittee on colorectal cancer screening. 2001-
Chairman – Professor Graeme Young, Australia
5. Committee member, working group, 1st UICC International workshop on screening for
colorectal cancer, an international agenda.
Chairman – Professor Bernard Levin, Graeme Young.
6. Council Member, Americal Gastroenterological Association, GI oncology section. 2002-
7. Committte member, OMED (World Organisation of Digestive Endoscopy) Screening
Committee, 2003-
8. Board of Governors, Journal of Gastroenterology and Hepatology Foundation, 2003-
9 Committee member, Practice Parameters Committee, American College of
Gastroenterology, USA, 2003-2007
 61 BCY Wong - 18 August, 2010

10. Committee member, Guidelines and Publications Committee, WGO-OMGE (World

Gastroenterology Organisation) 2005-2009
11. Committee, International Asian Conference on Cancer Screening, 2005-
12. Board of Directors, International Society of Gastroenterological Carcinogenesis, 2008
13. Editor, Upper GI and Pancreatic Diseases Cochrane Group
14. Advisor, OMED CRC Screening Committee, 2009
15. Council member, Asian Pacific Association of Gastroenterology, 2009.

Local:
1. Honorary Secretary, Center for Alimentary Research and Education, Faculty of Medicine,
University of Hong Kong. 1998-2010
2. Fellow, Cancer Research Center, Faculty of Medicine, University of Hong Kong. 1997-
3. Member, Steering Committee on Professional Education, Cancer Center, Queen Mary
Hospital, Hong Kong. 1999-
4. Committee member, The Federation of Medical Societies of Hong Kong, 2001-
5. Council Member, Hong Kong Society of Gastroenterology, Hong Kong. 2002-
6. Committee member, Examination Committee, Hong Kong College of Physicians. 2002-
7. Member, Institutional Review Board, University of Hong Kong and Hospital Authority.
2003-2010
8. Deputy Chairman, Institutional Review Board, HKU/HA Hong Kong West, 2005-2010
9. Vice President, Hong Kong Society of Gastroetnerology, 2008-2010
10. Founding council member, Hong Kong IBD Society, 2008-
11. President, Hong Kong Society of Gastroetnerology, 2010-2012
 62 BCY Wong - 18 August, 2010

13. PUBLICATIONS:
Book and Book Chapters: 21
Original articles: 326
Original articles (local journals): 12
Conference proceedings: 317

BOOK AND BOOK CHAPTERS

1. Wong BCY. Helicobacter pylori-related diseases in the Chinese. M.D. Thesis, University of
Hong Kong, 2000. MD Thesis.

2. Wong BCY. Role of Helicobacter pylori and non steroidal anti-inflammatory drugs in
prevention of gastric cancer. 2005. Ph.D Thesis.

3. Wong BCY, Ching CK, Lam SK.

Helicobacter pylori infection- epidemiology and clinical significance among the elderly in Hong
Kong. In: The Health of the Elderly in Hong Kong. Eds: SK Lam. Hong Kong University Press,
Hong Kong. 1997, p63-74.

4. Wong BCY, Ching CK, Lam SK.

Upper gastrointestinal abnormalities in the elderly Helicobacter pylori carriers. In: The Health
of the Elderly in Hong Kong. Eds: SK Lam. Hong Kong University Press, Hong Kong. 1997,
p75-86.

5. Wong BCY, Lam SK.

Gastrointestinal carcinoma: hereditary or infectious disease? In: Bioregulation and its disorders
in the gastrointestinal tract. Eds: T Yoshikawa, T Arakawa. Blackwell Science, Japan.
1998 :p305-320.

6. Wong BCY, Zhu GH, Lam SK.

Cyclooxygenases, apoptosis and the gastrointestinal tract. (in Chinese)
In : New Theory and Technology of Gastroenterology. p 58-63. Eds: SD Xiao. Shanghai
Technology and Education Press, PR China, 1999.

7. Wong BCY, Fan XM, Lin MCM, Kung HF, Lam SK.
Cyclooxygenase-2 and protein kinase C signalling in gastric cancer.
In: Molecular Genetic Basis of Cancer. Pp224-229. Eds: Lung ML, Hsiao WLW. Hong Kong
University of Science and Technology, Hong Kong, 2001.

8. Wong BCY, Gu Q, Lam SK.

Diagnosis and treatment of Helicobacter pylori infection in Hong Kong.
In : Helicobacter pylori infection: basic and clinical aspects. Eds: FL Hu, DY Zhou. Chinese
Science and Technology Press, 2002; pp449-455.

9. Xia HHX, Wong BCY, Lam SK.

Helicobacter pylori infection and gastroduodenal mucosal damage and healing.
 63 BCY Wong - 18 August, 2010

In: Gastrointestinal mucosal repair and experimental therapeutics. Front Gastrointest Res. Eds:
CH Cho and JY Wang. S. Karger AG, Switzerland, 2002; 25: 143-157.

10. Wong WM, Wong BCY.

The Role of Helicobacter pylori in dyspepsia.
In: Hot Topics in GERD and Dyspepsia. Eds: R Fass. Hanley & Belfus, Inc., Philadelphia,
Pennsylvania, USA, 2003. pp 345-351.

11. Wong BCY, Xia HHX.

Prevention of gastric cancer by Helicobacter pylori eradication.
In: Heicobacter pylori-associated Gastric Cancer- Evidence of its Carcinogenesis. Ed: K
Sugano. Igaku-Shoin Ltd, Japan. 2004. pp 61-68 (Japanese), 69-72 (English).

12. Chan AOO, Wong BCY

Chemoprevention of gastric cancer.
In: Gastroenterology and Hepatology: Theoretic Basis and Clinical Advances. Ed. SD Xiao.
Shanghai World Press, 2003, Chap 5, section 13, pp 429-435.
胃腸病學和肝病學—基礎理論與臨床進展, 第五章, 第十三節: 胃癌的化學預防.
萧樹東主編, 上海世界圖書出版公司出版發行, 2004

13. Lai CL, Chen S, Wong BCY, Yuen RMF.

Gastroenterology and Hepatology.,
In: Lau CP, Chen MZ, Kumana CR, Lai CL, Lai KN, Lam KSL, Lam WK ed., Problem-based
medical cases management. Hong Kong University Press, 2005, 75-107.

14. Wong BCY, Wong WM, Smales R.

Gastroesophageal reflux disease and tooth erosion
In: Tooth Erosion: Prevention and Treatment. Ed: Yip KHK, Smales RJ, Kaidonis JA. Jaypee
Brothers Medical Publishers Ltd, New Delhi, India. 2006. pp 47-55. ISBN 81-8061-751-3.

15. Chan AOO, Wong BCY

General Mechanisms of Cancer
In: Alcohol, Tobacco and Cancer. Eds: Cho CH and Purohit V. Basel, Karger, Switzerland,
2006, pp1-12. ISBN 3-8055-8107-6.

16. Chan AOO, Liu CL, Wong BCY.

Choledochal cysts
In: ERCP. Ed: Baron T, Kozarek R, Carr-Locke D. Elsevier Inc 2008 Chapter 36. pp 387-392

17. Chan AOO, Wong BCY

Multi-disciplinary approach to intestinal gastric cancer
In: Gastrointestinal Oncology: A multidisciplinary approach. Ed: Jankowski J, Kerr D,
Sampliner R, Fong YM. Blackwell Publishing 2007

18. Textbook of Internal Medicine.

Associate Editor, People’s Medical Publishing House, Beijing, PR China, October 2007.
 64 BCY Wong - 18 August, 2010

19. Wong BCY, Cheung TK

Approach to the patient with gastrointestinal and liver disease.
In: Textbook of Internal Medicine. Ed: Wang JY. People’s Medical Publishing House, Beijing,
PR China, October 2007. Chapter 20. pp311-330.

20. Chan AOO, Wong BCY.

Deregulation of E-Cadherin in precancerous lesions and gastric cancer.
In: The Biology of Gastric Cancers. Ed: Wang T, Fox J, Giraud AS. Springer, 2008, Chapter 14,
pp 377-388.

21. Qiao L and Wong BCY

Experimental therapeutics of colon cancer,
In: Encyclopedia of Cancer. Ed: Manfred Schwab. Springer 2009. Reference.
 65 BCY Wong - 18 August, 2010

ORIGINAL ARTICLES :

ISI essential science indicators in Clinical Medicine: (Jun 2009)

Citation 3,375 out of 200 papers.
Citations per paper: 16.88
Rank 2748/ 16317 (0.17) out of top 1% most cited scientist in clinical medicine

Citation number: (up to Mar 2009)

5384 of 297 full papers
5436 of 297 full papers and 302 conference papers

Impact factor of 309 papers: (up to Sept 2009)

Total: 1190
Mean: 4.28

A) FULL ARTICLES IN INTERNATIONAL, REFEREED JOURNALS

1. Wong BCY, Lai CL.

Ascites in cirrhotic patients : pathophysiology and management.
Medical progress 1992; (19):9:18-21.
Contribution: first author

2. Lai CL, Wong BCY, Yeoh EK, Lim WL, Chang WK.
Five year follow-up of a prospective randomised trial of hepatitis B recombinant
DNA yeast vaccine vs plasma-derived vaccine in children. Immunogenicity and
anamnestic responses.
Hepatology 1993;18:763-767.
Impact Factor: 9.503 Citation: 33 Contribution: major

3. Wong BCY, Wong KL, Ip MSM, Wang EP, Chan KW, Cheng LC.
Sjogren's syndrome with amyloid-A presenting as multiple pulmonary nodules.
Journal of Rheumatology 1994;21:165-167
Impact Factor: 2.674 Citation: 15 Contribution: first author

4. Lai KC, Yuen ST, Ching CK, Hu HC, Wong CY, Lai CL, Lam SK.
Tuberculosis of the common bile duct.
Illustrated case reports in Gastroenterology, 1994,1,5-11.

5. Ching CK, Leung KP, Yung RW, Lam SK, Wong BCY, Lai KC, Lai CL.
Prevalence of metronidazole resistant Helicobacter pylori strains among Chinese peptic
ulcer disease patients and normal controls in Hong Kong.
Gut 1996;38:675-8
Impact Factor: 5.883 Citation: 50 Contribution: intermediate
 66 BCY Wong - 18 August, 2010

6. Ching CK, Wong BCY, Kwok E, Ong L, Covacci A, Lam SK.

Prevalence of CagA bearing Helicobacter pylori strains detected by the anti-Cag A assay in
patients with peptic ulcer disease and controls.
Am J Gastroenterol 1996;91:949-953
Impact Factor: 4.172 Citation: 98 Contribution: major

7. Lai KC, Hui WM, Wong BCY, Ching CK, Lam SK.
A retrospective and prospective study on the safety of discharging selected patients with
duodenal ulcer bleeding on the same day as endoscopy.
Gastrointestinal endoscopy 1997;45:26-30
Impact Factor: 3.328 Citation: 51 Contribution: major

8. Lai CL, Ching CK, Tung AKM, Li E, Young J, Hill A, Wong BCY, Dent J, Wu PC.
Lamivudine is effective in suppressing Hepatitis B virus DNA in Chinese hepatitis B
surface antigen carriers: a placebo-controlled trial.
Hepatology 1997; 25:241-244
Impact Factor: 9.503 Citation: 199 Contribution: intermediate

9. Lam SK, Ching CK, Lai KC, Wong BCY, Lai CL, Chan CK, Ong L.
Does treatment of Helicobacter pylori with antibiotics alone heal duodenal ulcer? A
randomised double-blind placebo-controlled study.
Gut 1997, 41:43-48.
Impact Factor: 5.883 Citation: 56 Contribution: intermediate

10. Wong BCY, Lam SK, Gao Z, Chen JS, Hu WHC, Ching CK, Lai KC, Ho J, Yuen ST, Hui
WM, Chen BW, Wang WH, Chen JS, Hou XH, Jiang XW, Lu JY, A Covacci.
Helicobacter pylori and gastric cancer. (in Chinese)
Chinese Journal of Gastroenterology 1997;2:129-131.
Contribution: first author

11. Wong BCY, Ching CK, Lam SK, Li ZL, Chen BW, Li YN, Liu HJ, Liu JB, Wang BE,
Yuan SZ, Xu CP, Hou XH, Zhang AT, Zheng ZT.
Differential north to south gastric cancer-duodenal ulcer gradient in China.
J Gastroenterol Hepatol 1998; 13: 1050-1057.
Impact Factor: 1.530 Citation: 30 Contribution: first author

12. Wong BCY, Lam SK.

Epidemiology of gastric cancer in relation to diet and Helicobacter pylori infection.
J Gastroenterol Hepatol. 1998; 13 (Suppl.) S166-S172
Impact Factor: 1.530 Citation: 4 Contribution: first and corresponding author

13. Tsang K, Lam SK, Lam WK, Karlberg J, Wong BC, Hu WH, Yew WW, Ip MS.
High sero-prevalence of Helicobacter pylori in active bronchiectasis.
Am. J Resp Crit Care Med 1998; 158: 1047-51.
Impact Factor: 8.876 Citation: 40 Contribution: minor
 67 BCY Wong - 18 August, 2010

14. Lam SK, Wong BCY.

Helicobacter pylori, peptic ulcer and gastric cancer in China.
Yale J Biol Med 1998; 71(1): 1-6.
Impact Factor: 0.381 Citation: 1 Contribution: senior/last author

15. Zhu GH, Yang XL, Lai KC, Ching CK, Wong BCY, Yuen ST, Ho J, Lam SK.
Nonsteroidal antiinflammatory drugs could reverse Helicobacter pylori-induced
apoptosis and proliferation in gastric epithelial cells.
Dig Dis Sci 1998;43(9): 1957-63.
Impact Factor: 1.387 Citation: 38 Contribution: intermediate

16. Ding SZ, Lam SK, Yuen ST, Wong BCY, Hui WM, Ho J, Guo X, Cho CH.
Prostaglandin, tumour necrosis factor  and neutrophils: causative relationship in
indomethacin-induced stomach injuries.
European J Pharmacol 1998; 348: 257-263.
Impact Factor: 2.352 Citation: 25 Contribution: intermediate

17. Wong BCY, Lam SK, Lai KC, Hu WHC, Ching CK, Ho J, Yuen ST, Chan CK, Lau GKK,
Lai CL.
Triple therapy for Helicobacter pylori eradication is more effective than long-term
maintenance anti-secretory treatment in the prevention of recurrence of duodenal ulcer: a
prospective long-term follow-up study.
Aliment Pharmacol Ther 1999; 13: 303-309.
Impact Factor: 3.529 Citation: 36 Contribution: first author

18. Wong BCY, Lam SK, Ching CK, Hu WHC, Kwok E, Gao Z, Chen JS, Lai KC, Ong LY,
Chen BW, Wang QH, Jiang XW, Hou XH, Lu JY.
Differential Helicobacter pylori infection rates in two contrasting gastric cancer risk regions
of South China.
J Gastroenterol Hepatol 1999; 14: 120-125
Impact Factor: 1.530 Citation: 26 Contribution: first author

19. Wong BCY, Lam SK, Ching CK, Hu WHC, Lai KC, Ong LY, Gao Z, Chen JS, Chen
BW, Jiang XW, Hou XH, Lu JY, Wang WH, Hui WM, Covacci A.
Seroprevalence of cytotoxin-producing Helicobacter pylori strains in Changle, an area
with very high prevalence of gastric cancer in South China.
Aliment Pharmacol Ther 1999; 13: 1295-1302.
Impact Factor: 3.529 Citation: 13 Contribution: first author

20. Zhu GH, Wong BCY, Eggo MC, Ching CK, Yuen ST, Chan EYT, Lai KC, Lam SK.
Nonsteroidal antiinflammatory drug-induced apoptosis in gastric cancer cells is blocked by
protein kinase C activation through inhibition of c-myc.
Brit J Cancer 1999: 79: 393-400.
Impact Factor: 3.894 Citation: 49 Contribution: corresponding author, first
author my Ph.D student

21. Zhu GH, Wong BCY, Ching CK, Lai KC, Lam SK.
 68 BCY Wong - 18 August, 2010

Differential apoptosis by indomethacin in gastric epithelial cells through the constitutive

expression of wild-type p53 and/or upregulation of c-myc.
Biochem Pharmacol 1999; 58: 193-200.
Impact Factor: 2.993 Citation: 33 Contribution: corresponding author, first
author my Ph.D student

22. Ng FH, Chow KC, Cheng CS, Kng C, WF Ng, Wong BCY.
High alpha-fetoprotein level in HCV-related nodular liver cell dysplasia.
Am J Gastroenterol 1999; 94: 2296-2297.
Impact Factor: 4.172 Citation: 1 Contribution: major

23. Wong BCY, Zhu GH, Lam SK.

Aspirin induced apoptosis in gastric cancer cells.
Biomedicine and Pharmacotherapy. 1999; 53: 315-318.
Impact Factor: 1.281 Citation: 33 Contribution: first author

24. Zhu GH, Wong BCY, Eggo MC, Yuen ST, Lai KC, Lam SK.
Pharmacological inhibition of protein kinase C activity could induce apoptosis in gastric
cancer cells by differential regulation of apoptosis-related genes.
Dig Dis Sci 1999; 44: 2020-6.
Impact Factor: 1.387 Citation: 22 Contribution: corresponding author, first
author my Ph.D student

25. Tsang KWT, Lam WK, Kwok E, Chan KN, Hu WHC, Ooi GC, Zheng L, Wong BCY,
Lam SK.
Helicobacter pylori and upper gastrointestinal symptoms in bronchiectasis
European Respiratory Journal 1999: 14; 1345-50.
Impact Factor: 2.999 Citation: 15 Contribution: minor

26. Wong BCY, Lam SK.

Diet and gastric cancer. GI cancer. 1999; 3: 1-10.
Citation: 6 Contribution: first author

27. Zhu GH, Wong BCY, Slosberg ED, Eggo MC, Ching CK, Yuen ST, Lai KC, Soh JW,
Weinstein IB, Lam SK.
Overexpression of protein kinase C 1 isoenzyme suppresses indomethacin-induced
apoptosis in gastric epithelial cells.
Gastroenterology 2000; 118: 507-514.
Impact Factor: 12.718 Citation: 40 Contribution: corresponding author, first
author my Ph.D student

28. Wang WH, Wong BCY, Lam SK.

Pooled analysis of Helicobacter pylori eradication regimes in Asia.
J Gastroenterol Hepatol 2000; 15: 1007-17.
Impact Factor: 1.530 Citation: 8 Contribution: corresponding author
 69 BCY Wong - 18 August, 2010

29. Wong BCY, Xiao SD, Hu FL, Qian SC, Huang NX, Li YY, Hu PJ, Daldiyono, Manan C,
Lesmana L, Carpio RE, Perez Jr. JY, Fock KM, Kachitorn U, Phornphutkul K,
Kullanvanijaya P, Ho J, Lam SK.
Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter
pylori-related duodenal ulcer: An Asian multicenter double-blind randomized placebo
controlled study.
Aliment Pharmacol Ther 2000; 14: 217-224.
Impact Factor: 3.529 Citation: 32 Contribution: first and corresponding author

30. Wong BCY, Wong WM, Tang VSY, Lai KC, Yuen ST, Hu WHC, Chan CK, Lau GKK,
Lai CL, Lam SK.
An Evaluation of Whole Blood Testing for Helicobacter pylori infection in Chinese.
Aliment Pharmacol Ther 2000; 14: 331-335.
Impact Factor: 3.529 Citation: 21 Contribution: first and corresponding author

31. Ma L, Chow JYC, Wong BCY, Cho CH.

Role of Capsaicin sensory nerves and EGF in the healing of gastric ulcer in rats.
Life Science 2000; 66: 213-220.
Impact Factor: 1.944 Citation: 13 Contribution: major

32. Ng FH, Wong SY, Ng WF, Wong BCY.

Prolonged storage of frozen unbuffered rapid urease test.
J Clin Gastroenterol 2000; 31: 142-3.
Impact Factor: 1.564 Citation: 2 Contribution: major

33. Wong WM, Wong BCY, Wong KW, Fung FMY, Lai KC, Hu WHC, Yuen ST, Lau
GKK, Lai CL, Chan CK, Lam SK.
13
C-urea breath test without a test meal is highly accurate for the detection of
Helicobacter pylori infection in Chinese.
Aliment Pharmacol Ther 2000; 14: 1353-8.
Impact Factor: 3.529 Citation: 29 Contribution: corresponding author, first author
my Ph.D student

34. Kersulyte D, Mukhopadhyay A, Velapatino B, Su WW, Pan ZJ, Garcia C, Hernandez V,

Valdez Y, Mistry RS, Gilman RH, Yuan Y, Gao H, Alarcon T, Brea ML, Nair GB,
Chowdhury A, Dutta S, Shirai M, Nakazawa T, Ally R, Segal I, Wong BCY, Lam SK,
Olfat F, Boren T, Engstrand L, Torres O, Schneider R, Thomas JE, Czinn S, Berg DE.
Differences in Genotypes of Helicobacter pylori from Different Human Populations.
J Bacteriol 2000: 182:3210-3218.
Impact Factor: 4.175 Citation: 99 Contribution: minor

35. Wang WH, Wong BCY , Mukhopadhyay AK, Berg DE, Cho CH, Lai KC, Hu WHC,
Lam SK.
High prevalence of Helicobacter pylori infection with dual resistance to
metronidazole and clarithromycin in Hong Kong.
Aliment Pharmacol Ther 2000; 14: 901-910.
Impact Factor: 3.529 Citation: 67 Contribution: corresponding author
 70 BCY Wong - 18 August, 2010

36. Tsang KW, Lam WK, Chan KN, Hu W, Wu A, Kwok E, Zheng L, Wong BCY, Lam SK.
Helicobacter pylori sero-prevalence in asthma.
Respir Med 2000; 94: 756-9.
Impact Factor: 1.419 Citation: 14 Contribution: minor

37. Lai KC, Hui WM, Wong BCY, Hu WH, Lam SK.
Ulcer-healing drugs are required after eradication of Helicobacter pylori in patients
with gastric ulcer but not duodenal ulcer haemorrhage.
Aliment Pharmacol Ther 2000 14: 1071-1076.
Impact Factor: 3.529 Citation: 12 Contribution: major

38. Wong BCY, Wong KW, Chan CK, Wong WM, Yuen MF, Lai KC, Hu WHC, Lau GKK,
Lai CL, Lam SK.
Evaluation of a new referral system for the management of dyspepsia in Hong Kong :
Role of open access upper endoscopy.
J Gastroenterol Hepatol 2000; 15: 1251-6.
Impact Factor: 1.530 Citation: 7 Contribution: first and corresponding author

39. Lai KC, Hui WM, Wong WM, Wong BCY, Hu WHC, Ching CK, Lam SK.
Treatment of Helicobacter pylori in patients with duodenal ulcer hemorrhage-a long
term randomized, controlled study.
Am J Gastroenterol 2000; 95: 2225-32.
Impact Factor: 4.172 Citation: 40 Contribution: intermediate

40. Wong BCY, Chang FY, Abid S, Abbas Z, Lin BR, van Rensburg C, Chen PC, Schneider
H, Simjee AE, Hamid SS, Seebaran A, Zhang J, DeStefano M, Lam SK.
Triple therapy with clarithromycin, omeprazole, and amoxicillin for eradication of
Helicobacter pylori in duodenal ulcer patients in Asia and Africa.
Aliment Pharmacol Ther 2000; 14: 1529-35.
Impact Factor: 3.529 Citation: 17 Contribution: first and corresponding author

41. Jeong JY, Mukhopadhyay AK, Dailidiene D, Wang YP, Velapatiño B, Gilman RH,
Parkinson AJ, Nair GB, Wong BCY, Lam SK, Mistry R, Segal I, Yuan Y, Gao H,
Alarcon T, Lopez Brea M, Gong Y, Goodwin A, Hoffman PS, Berg DE.
Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes
moderate and high-level metronidazole resistance in Helicobacter pylori.
J Bacteriology 2000; 182: 5082-90.
Impact Factor: 4.175 Citation: 61 Contribution: minor

42. Wong BCY, Lam SK.

Treatment regimes for Helicobacter pylori infection in Asia Pacific region. (in Chinese)
J Modern Digestion and Intervention 2000; 5: Suppl 46-48.

43. Jiang XH, Wong BCY, Yuen ST, Jiang SH, Cho CH, Lai KC, Lin MCM, Kung HF, Lam
SK.
 71 BCY Wong - 18 August, 2010

Arsenic trioxide induces apoptosis in human gastric cancer cells through upregulation of
p53 and activation of caspase 3.
Int J Cancer 2001; 91: 173-179.
Impact Factor: 4.375 Citation: 66 Contribution: corresponding author, first author my
Ph.D student

44. Guo X, Liu ESL, Ko JKS, Wong BCY, Ye YN, Lam SK, Cho CH.
Protective role of cyclooxygenase inhibitors in the adverse action of passive cigarette
smoking on the initiation of experimental colitis in rats.
Eur J Pharmacol 2001; 411: 193-203
Impact Factor: 2.352 Citation: 17 Contribution: intermediate

45. Wong BCY, Wong WM, Wang WH, Fung FMY, Lai KC, Chu KM, Yuen ST, Leung SY,
Hu WHC, Yuen MF, Lau GKK, Chan CK, Lam SK.
One-week Ranitidine Bismuth Citrate-based triple therapy for the eradication of
Helicobacter pylori in Hong Kong with high prevalence of metronidazole resistance.
Aliment Pharmacol Ther 2001; 15: 403-409
Impact Factor: 3.529 Citation: 24 Contribution: first and corresponding author

46. Xia HHX, Wong BCY, Talley NJ, Lam SK.

Helicobacter pylori infection- current treatment practice.
Experts Opinion on Pharmacotherapy 2001; 2: 253-266.
Citation: 6

47. Wong BCY, Wang WH, Berg DE, Fung FMY, Lai KC, Wong WM, Wong KW, Lam
SK.
High prevalence of mixed infections by Helicobacter pylori in Hong Kong:
metronidazole sensitivity and overall genotype.
Aliment Pharmacol Ther 2001; 15: 493-503.
Impact Factor: 3.529 Citation: 24 Contribution: first and corresponding author

48. Wong BCY, Wong WM, Wang WH, Tang VSY, Young J, Lai KC, Yuen ST, Leung SY,
Hu WHC, Chan CK, Hui WM, Lam SK.
An evaluation of invasive and non-invasive tests for the diagnosis of Helicobacter pylori
infection in Chinese.
Aliment Pharmacol Ther 2001; 15: 505-511.
Impact Factor: 3.529 Citation: 42 Contribution: first and corresponding author

49. Szeto ML, Lee CK, Yee YK, Li KF, Lee WK, Lee CC, Que TL, Wong BCY.
Evaluation of five commercial serological tests for detection of Helicobacter pylori
infection in Chinese.
Aliment Pharmacol Ther 2001; 15: 703-6.
Impact Factor: 3.529 Citation: 5 Contribution: senior/last author

50. Wong BCY, Wang WH, Wong WM, Lau GKK, Fung FMY, Kung NN, Chu KM, Lai
KC, Hu WHC, Hu FL, Liu XG, Chan CK, Yuen MF, Hui WM, Lam SK.
Three-day quadruple therapy is effective in treatment of Helicobacter pylori-related
 72 BCY Wong - 18 August, 2010

duodenal ulcers.
Aliment Pharmacol Ther 2001; 15: 843-850.
Impact Factor: 3.529 Citation: 13 Contribution: first and corresponding author

51. Chan AOO, Lam SK, Chu KM, Lam CM, Kwok E, Leung SY, Yuen ST, Law SY,
Hui WM, Lai KC, Wong CY, Hu HC, Lai CL, Wong J.
Soluble E-Cadherin is a valid prognostic marker in gastric carcinoma.
Gut 2001; 48: 808-11.
Impact Factor: 5.883 Citation: 25 Contribution: minor

52. Xia HHX, Wong BCY, Lam SK.

Helicobacter pylori infection and gastric cancer.
Asian Journal of Surgery 2001; 24: 217-221.
Citation: 12 Contribution: corresponding author

53. Kng C, Ng FH, Ng WF, Wong BCY, Grosso LE, Bacon BR.
A Chinese Patient with Non-HFE–linked Iron Overload.
J Clin Gastroenterol 2001; 33: 69-71.
Impact Factor: 1.564 Citation: 8 Contribution: minor

54. Wang WP, Guo X, Koo MWL, Wong BCY, Lam SK, Cho CH.
Protective effect of heme oxygenase-1 induction on the trinitrobenzene sulfonic acid
induced colitis in rats.
Am J Physiol Gastrointest Liver Physiol 2001; 281: G586.
Impact Factor: 3.421 Citation: 58 Contribution: minor

55. Fan XM, Wong BCY, Zhou XM, Wang WP, Lin MCM, Kung HF, Yuen ST, Leung
SY, Lam SK.
Inhibition of proteasome function induced apoptosis in gastric cancer cells.
Int J Cancer 2001: 93: 481-488.
Impact Factor: 4.375 Citation: 41 Contribution: corresponding author, first
author my Ph.D student

56. Liu ESL, Wong BCY, Cho CH.

The influence of gender difference and gastritis on gastric ulcer formation in rats
J Gastroenterol Hepatol 2001; 16: 740-747.
Impact Factor: 1.530 Citation: 7 Contribution: intermediate

57. Wong BCY, Wang WP, So WHL, Shin VY, Wong WM, Fung FMY, Hui WM, Lam SK,
Cho CH.
Epidermal growth factor and its receptor in chronic active gastritis and gastroduodenal
ulcer before and after Helicobacter pylori eradication.
Aliment Pharmacol Ther 2001: 15: 1459-1465.
Impact Factor: 3.529 Citation: 15 Contribution: first and corresponding author

58. Wong WM, Wong BCY, Li TM, Wong KW, Cheung KL, Fung FMY, Xia HHX, Lam
SK.
 73 BCY Wong - 18 August, 2010

Twenty-minute 50mg 13C-urea breath test without test meal for the diagnosis of
Helicobacter pylori infection.
Aliment Pharmacol Ther: 2001; 15: 1499-1504
Impact Factor: 3.529 Citation: 8 Contribution: corresponding author, first
author my Ph.D student

59. Chan AOO, Wong BCY, Lam SK.

Gastric cancer: past, present and future
Canadian J Gastroenterology 2001: 15(7): 469-474.
Impact Factor: 1.265 Citation: 15 Contribution: major.

60. Zhou XM, Wong BCY, Fan XM, Zhang HB , Lin MCM, Kung HF, Fan DM, Lam SK.
Non-steroidal antiinflammatory drugs induced apoptosis in gastric cancer cells through
up-regulation of bax and bak.
Carcinogenesis 2001; 22(9): 1393-1397
Impact Factor: 4.543 Citation: 55 Contribution: corresponding author

61. Wong BCY, Wang WP, Lin MCM, Leung SY, Yuen ST, Chu KM, Hui WM, Kung HF,
Lam SK.
12-lipoxygeanse inhibition induced apoptosis in human gastric cancer cells.
Carcinogenesis 2001; 22(9): 1349-1354.
Impact Factor: 4.663 Citation: 45 Contribution: first and corresponding author

62. Huang XR, Hui CWC, Chen YX, Wong BCY, Fung PCW, Metz C, Cho CH, Hui WM,
Bucala R, Lam SK, Lan HY.
Macrophage Migration inhibitory factor is an important mediator in the pathogenesis of
gastric inflammation.
Gastroenterology 2001; 121(3): 619-630
Impact Factor: 12.718 Citation: 31 Contribution: major

63. Wong WM, Wong BCY, Tang VSY, Lai KC, Yuen ST, Leung SY, Hu WHC, Lam SK
An evaluation of Pyloritek test for the diagnosis of Helicobacter pylori infection in
Chinese – before and after eradication therapy.
J Gastroenterol Hepatol 2001; 16(9): 976-980
Impact Factor: 1.530 Citation: 6 Contribution: corresponding author, first
author my Ph.D student

64. Wong BCY, Wong WM, Yee YK, Hung WK, Yip AWC, Szeto ML, Li KF, Lau P, Fung
FMY, Tong TSM, Lai KC, Hu WHC, Yuen MF, Hui CK, Lam SK
Rabeprazole based 3-day and 7-day triple therapy versus 7-day omeprazole based triple
therapy for the treatment of Helicobacter pylori infection.
Aliment Pharmacol Ther 2001; 15: 1959-65.
Impact Factor: 3.529 Citation: 28 Contribution: first and corresponding author

65. Xia HHX, Wong BCY, Wong KW, Wong SY, Wong WM, Lai KC, Hu WHC, Chan CK,
Lam SK.
 74 BCY Wong - 18 August, 2010

Clinical and endoscopic characteristics of non-Helicobacter pylori, non-NSAID

duodenal ulcers: a long-term prospective study.
Aliment Pharmacol Ther 2001; 15: 1875-1882
Impact Factor: 3.529 Citation: 22 Contribution: corresponding author

66. Fan XM, Wong BCY, Lin MCM, Cho CH, Wang WP, Kung HF, Lam SK.
IL-1beta induces COX-2 expression in gastric cancer cells by the p38 and p44/42 MAP
kinase signaling pathways.
J Gastroenterol Hepatol 2001;16(10): 1098-1104.
Impact Factor: 1.530 Citation: 42 Contribution: corresponding author, first
author my Ph.D student

67. Jiang XH, Wong BCY, Lin MCM, Zhu GH, Kung HF, Jiang SH, Yang D, Lam SK.
Functional p53 is required for Triptolide-induced apoptosis and AP-1 and Nuclear
Factor-B activation in Gastric cancer cells
Oncogene 2001; 20(11): 8009-8018.
Impact Factor: 6.495 Citation: 52 Contribution: corresponding author, first
author my Ph.D student

68. Wong BCY, Yin Y, Berg DE, Xia HHX, Wang WH, Zhang JZ, Wong WM, Huang XR,
Tang VSY, Lam SK.
Distribution of distinct vacA, cagA and iceA alleles in Helicobacter pylori in Hong Kong.
Helicobacter 2001; 6(4): 317-324.
Impact Factor: 2.624 Citation: 23 Contribution:first and corresponding author

69. Jing DD, Zhang YL, Li XR, Wong BCY.

Screening and surveillance of colorectal cancer in China.
Chinese Journal of Gastroenterology 2001; 6(4): 244-251.

70. Wong WM, Mandir N, Goodlad RA, Wong BCY, Garcia SB, Lam SK, Wright NA.
Histogenesis of human colonic adenomas – the role of cell proliferation and crypt fission.
Gut 2002; 50(2): 212-217.
Impact Factor: 5.883 Citation: 45 Contribution: minor, first author my Ph.D
student

71. Wong WM, Lai K, Lau C, Hu W, Chen W, Wong BCY, Hui W, Wong N, Xia H, Lam
SK.
Upper gastrointestinal evaluation of Chinese patients with noncardiac chest pain
Aliment Pharmacol Ther 2002; 16(3): 465-472.
Impact Factor: 3.529 Citation: 27 Contribution: minor, first author my Ph.D
student

72. Xia HHX, Wong BCY, Wong WM, Tang VSY, Cheung HKL, Sham FNF, Fung FMY,
Lai KC, Hu WHC, Chan CK, Lam SK
Optimal serological tests for the detection of Helicobacter pylori infection in Chinese
population.
Aliment Pharmacol Ther 2002; 16(3): 521-526.
 75 BCY Wong - 18 August, 2010

Impact Factor: 3.529 Citation: 12 Contribution: corresponding author

73. Wong WM, Wong BCY, Lu H, Gu Q, Y Yin, Wang WH, Fung FMY, Lai KC, Xia
HHX, Xiao SD, Lam SK.
One-week omeprazole, furazolidone and amoxycillin rescue therapy after failure of
Helicobacter pylori eradication with standard triple therapies
Aliment Pharmacol Ther 2002; 16(4): 793-8.
Impact Factor: 3.529 Citation: 30 Contribution: corresponding author, first
author my Ph.D student

74. Wong WM, Wong BCY, Xia H, Tang V, Lai KC, Hu WHC, Yuen MF, Chan CK, Lam
SK.
An evaluation of a rapid urine test for the diagnosis of Helicobacter pylori infection in
Chinese
Aliment Pharmacol Ther 2002; 16(4): 813-7.
Impact Factor: 3.529 Citation: 10 Contribution: corresponding author, first
author my Ph.D student

75. Médigue C, Wong BCY, Lin MCM, Bocs S, Danchin A.

The secE gene of Helicobacter pylori
J Bacteriol 2002 ; 184: 2837-40.
Impact Factor: 4.175 Citation: 5 Contribution: major

76. Wong BCY, Jiang XH, Lam SK

Role of cyclooxygenase-2 and gastric cancer. (in Chinese)
J Modern Digestion and Intervention 2002; 7(5): 69-70.
Contribution: first author

77. Huang JJ, Bai YX, Jing DD, Wong BCY, Han SW, Lin J, Xu B, Huang CF, Lin MCM,
Kung HF
Ectopic expression of a C-terminal fragment of the human telomerase reverse
transcriptase leads to telomere dysfunction and reduction of growth and
tumorigenicity in HeLa cells.
Cancer Research 2002; 62(11): 3226-32.
Impact Factor: 8.649 Citation: 7 Contribution: major

78. Ng FH, Wong WM, Wong BCY, Kng C, Wong SY, Lai KC, Cheng CS, Yuen WC,
Lam
SK, Lai CL. Sequential intravenous/oral antibiotic versus continuous intravenous
antibiotic in the treatment of pyogenic liver abscess.
Aliment Pharmacol Ther 2002; 16(6):1083-90.
Impact Factor: 3.529 Citation: 3 Contribution: major

79. Yang Y, Wong BCY, Lam SK, Xia HHX.

Treatment of Helicobacter pylori infection
World Chinese Journal of Digestology 2002; 2(5): 195-201.
Contribution: major
 76 BCY Wong - 18 August, 2010

80. Lai KC, Lam SK, Chu KM, Wong BCY, Hui WM, Hu WHC, Lau GKK, Wong WM,
Yuen MF, Chan OO, Lai CL, Wong J.
Lansoprazole for the prevention of recurrent ulcer complications from long term low-
dose aspirin use.
N Engl J Med 2002 ;346(26): 2033-8.
Impact Factor: 34.833 Citation: 206 Contribution: major

81. Hu WHC, Lam KF, Wong YH, Lam CLK, Hui WM, Lai KC, Wong BCY, Lam SK.
The Hong Kong Index of Dyspepsia (HIDy): A validated symptom severity
questionnaire for paitents with dyspepsia.
J Gastroenterol. Hepatol. 2002; 17(5): 545-551.
Impact Factor: 1.530 Citation: 17 Contribution: minor

82. Xia HHX, Wong BCY.

Gastric biopsy-based rapid urease tests for the detection of Helicobacter pylori: Progress,
advantages and limitations.(ed)
J Gastroenterol Hepatol 2002; 17(6): 629-632.
Impact Factor: 1.530 Citation: 4 Contribution: senior/last author

83. Ng FH, Lai KC, Wong BCY, Wong WM, Wong SY, Chow KC, Yuen ST, Leung SY,
Lam SK.
13
C-urea breath test without prior fasting and without test meal is accurate for the
detection of Helicobacter pylori infection in Chinese.
J Gastroenterol Hepatol 2002; 17(8): 834-8.
Impact Factor: 1.530 Citation: 6Contribution: corresponding author

84. Wong WM, Wong BCY, Hui CK, Ng M, Lai KC, Tso WK, Lam SK, Lai CL.
Pyogenic Liver Abscess - retrospective analysis of 80 cases over a 10-year period.
J Gastroenterol Hepatol 2002; 17(9): 1001-7.
Impact Factor: 1.530 Citation: 35 Contribution: major, first author my
Ph.D student

85. Zhang HB, Wong BCY, Zhou XM, Guo XG, Zhao SJ, Wang JH, Wu KC, Ding J, Lam
SK, Fan DM.
Effects of somatostatin, octreotide and pitressin plus nitroglycerine on systemic and
portal haemodynamics in the control of acute variceal bleeding.
International Journal of Clinical Practice 2002; 56(6): 447-51
Impact Factor: 1.137 Citation: 3 Contribution: major

86. Yuen MF, Poon RTP, Lai CL, Fan ST, Lo CM, Wong KW, Wong BCY.
A Randomized Placebo-Controlled Study of Long-acting Octreotide for Advanced
Hepatocellular Carcinoma
Hepatology 2002; 36(9): 687-691.
Impact Factor: 9.503 Citation: 109 Contribution: corresponding author
 77 BCY Wong - 18 August, 2010

87. Jiang XH, Lam SK, Lin MCM, Jiang XH, Kung HF, Slosberg ED, Soh JW, Weinstein
IB, Wong BCY.
Novel target for induction of apoptosis by cyclooxygenase-2 inhibitor through a protein
kinase C-1-dependent pathway
Oncogene 2002; 21(39): 6113-6122.
Impact Factor: 6.495 Citation: 52 Contribution: corresponding author, first
author my Ph.D student

88. Wong WM, Wong BCY, Hung WK, Yee YK, Yip AWC, Szeto ML, Fung FMY, Tong
TSM, Lai KC, Hu WHC, Yuen MF, Lam SK.
Double-blind, randomized, placebo-controlled study of four weeks lansoprazole for the
treatment of functional dyspepsia in Chinese population.
Gut 2002; 4(10):502-506.
Impact Factor: 6.323 Citation: 43 Contribution: corresponding author, first
author my Ph.D student

89. Xia HHX, Wong BCY, Talley NJ, Lam SK.

Alternative and “rescue” treatment regimens for Helicobacter pylori eradication
Expert Opin Pharmacother 2002; 3(9): 1301-1311
Citation: 27 Contribution: major

90. Xia HHX, Wong BCY.

First line and rescue therapy for Helicobacter pylori infection.
Natl Med J China 2002; 82(8 suppl)13-17.
Contribution: senior/last author

91. Yuen MF, Sablon E,Yuan HJ, Hui CK, Wong DKH, Doutreloigne J, Wong BCY, Chan
AOO, Lai CL.
The relationship between the development of precore and core promoter mutations and
HBeAg seroconversion in chronic hepatitis B
J Infectious Diseases 2002; 186(11): 1335-8.
Impact Factor: 4.481 Citation: 40 Contribution: intermediate

92. Wong WM, Lam SK, Xia HHX, Tang VSY, Lai KC, Hu WHC, Chan CK, Cheung
KL, Wong BCY.
Accuracy of a new near patient test (Signify H. pylori) for the diagnosis of Helicobacter
pylori infection.
J Gastroenterol Hepatol 2002; 17(12): 1272-77.
Impact Factor: 1.521 Citation: 7 Contribution: corresponding author, first
author my Ph.D student

93. Wong BCY, Wong WM, Chan JFK, Lai K, Hu W, Chan CK, Lam SK, Carr-Locke DL.
Virtual colonoscopy for the detection of colorectal polyps and cancers in a average risk
population without pre-selection of cases
J Gastroenterol Hepatol 2002; 17(12): 1323-27.
Impact Factor: 1.521 Citation: 7 Contribution: first and corresponding author
 78 BCY Wong - 18 August, 2010

94. He XX, Wong BCY, Lam SK, Xia HHX.

Diagnosis of Helicobacter pylori infection.
Diagnosis and Treatment of Digestive Diseases 2002; 2:241-245. (Review)(Chinese)
Contribution: major

95. Wong WM, Lam SK, Hui WM, Lai KC, Chan CK, Hu WHC, Xia HH, Hui CK, Yuen
MF, Chan AOO, Wong BCY.
Long-term prospective follow-up of endoscopic esophagitis in southern Chinese –
prevalence and spectrum of the disease
Aliment Pharmacol Ther 2002; 16(12): 2037-42.
Impact Factor: 2.98 Citation: 46 Contribution: senior/last author, first
author my Ph.D student

96. Hung WK, Wong WM, Wong GSW, Yip AWC, Szeto ML, Lai KC, Hu WHC, Chan
CK, Xia HHX, Yuen MF, Lam SK, Wong BCY.
One-week ranitidine bismuth citrate, amoxycillin and metronidazole triple therapy for
the treatment of Helicobacter pylori infection in Chinese
Aliment Pharmacol Ther 2002; 16(12): 2067-72.
Impact Factor: 2.98 Citation: 7 Contribution: corresponding author

97. Hu WHC, Wong WM, Lam CLK, Lam KF, Hui WM, Lai KC, Xia HHX, Lam SK,
Wong BCY.
Anxiety but not depression determines health seeking behaviour in Chinese patients with
dyspepsia and irritable bowel syndrome: a population based study.
Aliment Pharmacol Ther 2002; 16(12): 2081-88.
Impact Factor: 2.98 Citation: 36 Contribution: senior/last author

98. Xia HHX, Zhang GS, Talley NJ, Wong BCY, Yang Y, Henwood C, Wyatt JM, Adams
S, Cheung K, Xia B, Zhu YQ, Lam SK.
Topographic association of gastric epithelial expression of Ki-67, bax and Bcl-2 with
antralization in the gastric incisura, body and fundus.
Am J Gastroenterol 2002; 97(12): 3023-31.
Impact Factor: 4.172 Citation: 9 Contribution: intermediate

99. Wang WH, Hu FL, Wong BCY, Berg DE, Lam SK.
Inhibitory effects of aspirin and indoemethacin on the growth of Helicobacter pylori in
vitro.
Chinese Journal of Digestive Diseases 2002; 3(12): 172-177.
Citation: 1 Contribution: intermediate

100. Wong BCY, Xia HHX, Cheung HKL, Ng FH, Wong SY, Chow KC, Lin SK, Yin Y,
Wong WM, Yuen MF, Lam SK.
Evaluation of two stool antigen tests for the detection of Helicobacter pylori infection
in Chinese population
J Gastroenterol Hepatol 2003; 18(1): 26-31
Impact Factor: 1.530 Citation: 7 Contribution:first and corresponding author
 79 BCY Wong - 18 August, 2010

101. Hui CK, Lai KC, Ng M, Wong WM, Yuen MF, Lam SK, Lai CL, Wong BCY.
Retained common bile duct stones: a comparison between biliary stenting to complete
clearance of stones by electrohydraulic lithotripsy.
Aliment Pharmacol Ther 2003; 17(2): 289-96.
Impact Factor: 3.529 Citation: 23 Contribution: corresponding author

102. Cho CH, Wu S, Wong TM, Leung WHL, Liu ESL, Chu KM, Shin VY, Ye YN, Wong
BCY.
Morphine as a drug for stress ulcer prevention and healing in the stomach
Eur J Pharmacol2003; 460(2-3): 177-82.
Impact Factor: 2.352 Citation: 9 Contribution: senior/last author

103. Yang Y, Deng CS, Peng JZ, Wong BCY, Lam SK, Xia HHX.
Effect of Helicobacter pylori on apoptosis and related genes in gastric epithelial cells.
Molecular Pathology 2003; 56(1): 19-24.
Impact Factor: 1.263 Citation: 28 Contribution: Minor

104. Xia HHX, Lai KC, Lam SK, Hu WHC, Wong NYH, Hui WM, Lau CP, Chen WH,
Chan CK, Wong WM, Wong BCY.
Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy
negative non-cardiac chest pain patients
Aliment Pharmacol Ther 2003; 17(3): 369-77.
Impact Factor: 3.529 Citation: 37 Contribution: senior/last author

105. Huang J, Xiu Bai Y, Wen Han S, Ng SS, Dao Jing D, Wong BC, Huang C, Kung H,
Lin MC.
A human TERT C-terminal polypeptide sensitizes HeLa cells to H2O2-induced
senescence without affecting telomerase enzymatic activity
Biochem Biophys Res Commun. 2003; 301(3): 627-32.
Impact Factor: 2.836 Citation: 5 Contribution: minor

106. Wu J, Xia HHX, Tu SP, Fan DM, Lin MCM, Kung HF, Lam SK, Wong BCY.
15-lipoxygenase-1 mediates cyclooxygenase-2 inhibitor-induced apoptosis in gastric
cancer
Carcinogenesis2003; 24(2): 243-7
Impact Factor: 4.663 Citation: 36 Contribution: corresponding author

107. Yuen MF, Yuan HJ, Hui CK, Wong DKH, Wong WM, Chan AOO, Wong BCY,
Lai CL.
A large population study of spontaneous HBeAg seroconversion and acute
exacerbation of chronic hepatitis B infection: implications for antiviral therapy
Gut 2003; 52(3): 416-9.
Impact Factor: 5.883 Citation: 35 Contribution: Intermediate

108. Wong WM, Lam SK, Lai KC, Chu KM, Xia HH, Wong KW, Cheung KL, Lin
SK, Wong BCY
 80 BCY Wong - 18 August, 2010

A rapid-release 50mg tablet-based 13C-urea breath test for the diagnosis of

Helicobacter pylori infection in Chinese
Aliment Pharmacol Ther 2003; 17(2): 253-7
Impact Factor: 3.529 Citation: 14 Contribution: corresponding author, first
author my Ph.D student

109. Wang WH, Wong WM, Dailidiene D , Berg DE, Gu Q, Lai KC, Lam SK, Wong
BCY.
Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to
antimicrobial agents
Gut 2003; 52(4): 490-495
Impact Factor: 5.883 Citation: 25 Contribution: corresonding author

110. Chan AOO, Lam SK, Wong BCY, Wong WM, Yeung YH, Hui WM, Rashid A,
Kwong YL.
Promoter methylation of E-cadherin gene in gastric mucosa associated with
Helicobacter pylori infection and in gastric cancer.
Gut 2003; 52(4): 502-6.
Impact Factor: 5.883 Citation: 63 Contribution: Major

111. Wong BCY, Jiang XH, Fan XM, Lin MCM, Jiang SH, Lam SK, Kung HF.
Suppression of RelA/p65 nuclear translocation independent of IB- degradation by
cyclooxygenase-2 inhibitor in gastric cancer.
Oncogene 2003; 22(8): 1189-97.
Impact Factor: 6.495 Citation: 43 Contribution: first and corresponding author

112. Wong WM, Gu Q, Lam SK, Fung FMY, Lai KC, Hu WHC, Yee YK, Chan CK,
Xia
HHX, Yuen MF, Wong BCY.
Randomised controlled study of rabeprazole, levofloxacin and rifabutin triple therapy
versus quadruple therapy as second-line treatment of Helicobacter pylori infection
Aliment Pharmacol Ther 2003; 17(4): 553-60.
Impact Factor: 3.529 Citation: 58 Contribution: corresponding author, first
author my Ph.D student

113. Xia HHX, Wong BCY, Lam SK

Chemoprevention of gastric cancer: current status
Chinese Medical Journal 2003; 116(1): 5-10
Impact Factor: 0.393 Citation: 5 Contribution: corresponding author

114. Wong WM, Cheng C, Wong BCY, Hui WM.

Non-ulcer dyspepsia.
Medical Progress 2003; 30(2): 12-19.
Contribution: Major, first author my Ph.D
student

115. Lai KC, Lau CS, Ip WY, Wong BC, Hui WM, Hu WH, Wong RW, Lam SK.
 81 BCY Wong - 18 August, 2010

Effect of treatment of Helicobacter pylori on the prevention of gastroduodenal ulcers

in patients receiving long-term NSAIDs: a double-blind, placebo-controlled trial.
Aliment Pharmacol Ther. 2003; 17(6): 799-805.
Impact Factor: 3.529 Citation: 29 Contribution: intermediate

116. Zhang ST, Wong WM, Hu WHC, Trendell-Smith N, Wong BCY.

Esophageal injury due to iron tablets
J Gastroenterol Hepatol 2003; 18(4): 466-7.
Impact Factor: 1.530 Citation: 3 Contribution: corresponding author

117. Hui CK, Yuen MF, Sablon E, Chan AOO, Wong BCY, Lai CL.
Interferon and Ribavirin Therapy for Chronic Hepatitis C Genotype 6: A Comparison
with Genotype 1.
J Infectious Diseases 2003; 187: 1071-4.
Impact Factor: 4.481 Citation: 25 Contribution: intermediate

118. Chu KM, Yuen ST, Wong WM, Wong KW, Lai KC, Hu W, Leung SY, Yuen
MF, Lam SK, Wong BCY.
A prospective comparison of performance of biopsy forceps used in single passage
with multiple bites during upper endoscopy.
Endoscopy 2003; 35(4): 338-42.
Impact Factor: 3.227 Citation: 2 Contribution: senior/last author

119. Yuen MF, Sablon E, Yuan HJ, Wong DKH, Hui CK, Wong BCY, Chan AOO,
Lai CL.
Significance of Hepatitis B genotype in acute exacerbation, HBeAg seroconversion,
cirrhosis-related complications and hepatocellular carcinoma.
Hepatology 2003; 37(3): 562-567.
Impact Factor: 9.503 Citation: 90 Contribution: intermediate

120. He XX, Hu PJ, Wong BCY, Lam SK, Xia HHX.

Chronic Helicobacter pylori infection induces apoptosis-resistance in gastric epithelial
cells.
Natl Med J China 2003; 83(1): 42-45.
Contribution: intermediate

121. Yuen MF, Sablon E, Hui CK, Li TM, Yuan HJ, Wong DKH, Doutreloigne J,
Bogaerts V, Wong BCY, Fan ST, Lai CL.
Prognostic Factors in Severe Exacerbation of Chronic Hepatitis B.
Clinical Infectious Disease 2003; 36(8): 979-84.
Impact Factor: 5.393 Citation: 11 Contribution: intermediate

122. Chan AOO, Wong BCY, Lan HY, Loke SL, Chan WK, Hui WM, Yueng YH, Hou L,
Luk JMC, Lam SK.
Deregulation of E-cadherin-catenin complex in precancerous lesions of gastric
adenocarcinoma
J Gastroenterol Hepatol 2003; 18(5): 534-39.
 82 BCY Wong - 18 August, 2010

Impact Factor: 1.530 Citation: 14 Contribution: corresponding author

123. Wong WM, Lam SK, Cheung KL, Tong TSM, Rozen P, Young GP, Chu KW,
Ho J, Law WL, Tung HM, Choi HK, Lee YM, Lai KC, Hu WHC, Chan CK, Yuen MF,
Wong BCY.
Evaluation of an automated immunochemical faecal occult blood test for colorectal
neoplasia screening in a Chinese population
Cancer 2003; 97(10): 2420-4.
Impact Factor: 4.017 Citation: 25 Contribution: corresponding author, first
author my Ph.D student

124. Yuen MF, Ooi CGC, Hui CK, Wong WM, Wong BCY, Chan AOO, Lai CL.
A pilot study of transcatheter arterial interferon embolisation for patients with
hepatocellular carcinoma.
Cancer 2003; 97(11): 2776-82.
Impact Factor: 4.017 Citation: 5 Contribution: intermediate

125. Wong WM, Lam KF, Lai KC, Hui WM, Hu WHC, Lam CLK, Wong NYH, Xia
HHX, Chan AOO, Lam SK, Wong BCY.
A validated symptoms questionnaire (Chinese-GERDQ) for the diagnosis of gastro-
oesophageal reflux disease in the Chinese population
Aliment Pharmacol Ther 2003; 17(11): 1407-13.
Impact Factor: 3.529 Citation: 23 Contribution: corresponding author, first
author my Ph.D student

126. Cheng C, Wong WM, Lai KC, Wong BCY, Hu WHC, Hui WM, Lam SK.
Psychosocial factors in patients with noncardiac chest pain.
Psychosom Med 2003; 65(3): 443-9.
Impact Factor: 3.687 Citation: 11 Contribution: intermediate

127. Yuen MF, Chan AOO, Wong BCY, Hui CK, Ooi GC, Tso WK, Yuan HJ, Wong
DKH, Lai CL.
Transarterial chemoembolization for inoperable, early-stage hepatocellular carcinoma
in patients with child-pugh grade A and B: Results of a comparative study in 96
Chinese patients
Am J Gastroenterol 2003; 98(5): 1181-5.
Impact Factor: 4.172 Citation: 23 Contribution: intermediate

128. Xia HHX, Lam SK, Wong WM, Hu WHC, Lai KC, Wong SH, Leung SY, Yuen
ST, Wright NA, Wong BCY.
Antralization at the edge of proximal gastric ulcers: Does Helicobacter pylori
infection play a role?
World J Gastroenterol 2003; 9(6): 1265-9.
Impact Factor: 3.318 Citation: 6 Contribution: corresponding author

129. Chan AO, Chu KM, Lam SK, Wong BC, Kwok KF, Law S, Ko S, Hui WM, Yueng
YH, Wong J.
 83 BCY Wong - 18 August, 2010

Soluble E-Cadherin is an independent pretherapeutic factor for long-term survival in

gastric cancer.
J Clin Oncol 2003; 21(12): 2288-93.
Impact Factor: 10.864 Citation: 19 Contribution: intermediate

130. Liu ESL, Ye YN, Shin VY, Yuen ST, Leung SY, Wong BCY, Cho CH.
Cigarette smoke exposure increases ulcerative colitis-associated colonic adenoma
formation in mice
Carcinogenesis 2003; 24(8): 1407-13.
Impact Factor: 4.663 Citation: 22 Contribution: intermediate

131. Chan AOO, Lam SK, Wong BCY, Kwong YL, Rashid A.
Gene methylation in non-neoplastic mucosa of gastric cancer: Age or Helicobacter
pylori related?
Am J Pathology 2003; 163(1): 370-3.
Impact Factor: 6.946 Citation: 8 Contribution: intermediate

132. Yuen MF, Sablon E, Wong DKH, Yuan HJ, Wong BCY, Chan AOO, Lai CL.
Role of Hepatitis B Virus Genotypes in Chronic Hepatitis B Exacerbation
Clinical Infectious Diseases 2003; 37(4): 593-7.
Impact Factor: 5.393 Citation: 14 Contribution: intermediate

133. Ng FH, Wong SY, Chang CM, Chen WH, Kng C, Lanas AI, Wong BCY.
High incidence of clopidogrel-associated gastrointestinal bleeding in patients with
prevous peptic ulcer disease.
Aliment Pharmacol Ther 2003; 18(4): 443-9.
Impact Factor: 3.529 Citation: 40 Contribution: corresponding author

134. Lewis AE, Wong BCY, Langman MJS, Eggo MC.

Protein kinase C inhibition induces DNA fragmentation in Colo 205 cells which is
blocked by cysteine protease inhibition but not mediated through caspase-3.
Experimental Cell Res 2003; 289(1): 1-10.
Impact Factor: 3.949 Citation: 6 Contribution: co-first author

135. Wong WM, Lai KC, Lam KF, Hui WM, Hu WHC, Lam CLK, Xia HHX, Huang
JQ,
Chan CK, Chan AOO, Lam SK, Wong BCY.
Prevalence, clinical spectrum and health care utilization of gastroesophageal reflux
disease in a Chinese population: a population-based study
Aliment Pharmacol Ther 2003: 18(6): 595-604
Impact Factor: 3.529 Citation: 87 Contribution: corresponding author, first
author my Ph.D student

136. Wong WM, Gu Q, Wang WH, Fung FMY, Berg DE, Lai KC, Xia HHX, Hu
WHC, Chan CK, Yuen MF, Hui CK, Chan AOO, Lam SK, Wong BCY.
 84 BCY Wong - 18 August, 2010

Effects of primary metronidazole and clarithromycin resistance on omeprazole,

metronidazole and clarithromycin triple therapy in a high metronidazole
resistanceregion
Clin Infect Dis 2003; 37: 882-9
Impact Factor: 5.393 Citation: 18 Contribution: corresponding author, first
author my Ph.D student

137. Hui CK, Lai KC, Yuen MF, Mg M, Chan CK, Hu W, Wong WM, Lai CL, Wong
BCY.
Does the addition of endoscopic sphincterotomy to stent insertion improve drainageof
the bile duct in acute suppurative cholangitis?
Gastrointestinal Endoscopy 2003; 58(4): 500-4.
Impact Factor: 3.328 Citation: 16 Contribution: corresponding author

138. Jiang XH, Wong BCY.

Cyclooxygenase-2 inhibition and gastric cancer.
Current Pharmaceutical Design 2003 ; 9(27): 2281-8.
Impact Factor: 5.550 Citation: 15 Contribution: corresponding author,
first author my Ph.D student

139. Lai KC, Lam SK, Chu KM, Hui WM, Kwok KF, Wong BCY, Hu HC, Wong WM,
Chan
OO, Chan CK.
Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in non-
steroidal anti-inflammatory drugs users – a randomized trial.
Aliment Pharmacol Ther 2003; 18(8): 829-36.
Impact Factor: 3.529 Citation: 25 Contribution: minor

140. Xia HH, Wong BCY.

Nitric oxide in Helicobacter pylori-induced apoptosis and its significance in gastric
carcinogenesis.
J Gastroenterol Hepatol 2003; 18(11): 1227-30
Impact Factor: 1.530 Citation: 7 Contribution: corresponding author

141. Au WY, Wong RW, Wong BCY, Lie AK, Liang R, Leung AY, Kwong YL.
Reduced incidence of acute graft versus host disease (GVHD) of the gut in Chinese
carriers of Helicobacter pylori during allogenic bone marrow transplantation.
Ann Hematol 2004; 83: 34-37. (2003: Oct 10: e-pub)
Impact Factor: 1.241 Citation: 2 Contribution: minor

142. Feng RE, Chen J, Cui QC, Zhan Y, Wong BCY

Expression of PKC beta-1 and PKC beta-2 in early gastric carcinoma
World Chin J Digestol 2003; 11(9): 1286-9. (in Chinese)

143. Xia HHX, Yang Y, Wong BCY

Relationship between Helicobacter pylori and gastroesophageal reflux diseases
Chin J Gastroenterol 2003; 8(4): 231-7. (in Chinese)
 85 BCY Wong - 18 August, 2010

144. Chan AOO, Wong WM, Lam SK, Wong BCY

Prevention of gastric cancer
Chinese Journal of Digestive Diseases 2003; 4(3): 100-4.

145. Wong WM, Lam SK, Tong TSM, Cheung KL, Tang VSY, Xia HHX, Lai KC, Hu
WHC,
Chan CK, Yuen MF, Chan AOO, Wong BCY.
Evaluation of a rapid stool antigen test for the diagnosis of Helicobacter pylori infection in
Chinese patients.
Chinese Journal of Digestive Diseases 2003; 4(3): 132-5.
Citation: 2 Contribution: corresponding author, first
author my Ph.D student

146. Wong BCY, Wong WM, Cheung KL, Tong TSM, Rozen P, Young GP, Chu KW,
Ho J,
Law WL, Tung HM, Lai KC, Hu WHC, Chan CK, Lam SK.
A Sensitive Guaiac Fecal Occult Blood Test is Less Useful than an Immunochemical
Test for Colorectal Cancer Screening in a Chinese Population
Aliment Pharmacol Ther 2003;18 (9): 941-6.
Impact Factor: 3.529 Citation: 23 Contribution: first and corresponding author

147. Tu SP, Jiang XH, Lin MCM, Cui JT, Yang Y, Lum CT, Zou B, Zhu YB, Jiang
SH,
Wong WM, Chan AO, Yuen MF, Lam SK, Kung HF, Wong BCY.
Suppression of survivin expression inhibits in vivo tumorigenicity and angiogenesis
in gastric cancer
Cancer Research 2003; 63(22): 7724-7732
Impact Factor: 8.649 Citation: 59 Contribution: corresponding author

148. Wong WM, Ho JC, Hung IF, Ng W, Lam YM, Tam WO, Wong BCY, Wong PC,
Lai
CL, Lam WK, Lam SK, Tsang KW, Ooi GC, Ho PL, Mok T, Chan J.
Temporal patterns of hepatic dysfunction and disease severity in patients with SARS
JAMA 2003; 290: 2663-5.
Impact Factor: 21.455 Citation: 13 Contribution: intermediate, first author
my Ph.D student

149. Wang WH, Huang JQ, Zhang GF, Lam SK, Karlberg, Wong BCY.
Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: A systematic
review and meta-analysis.
J Natl Cancer Inst 2003; 95(23): 1784-91.
Impact Factor: 13.844 Citation: 83 Contribution: corresponding author

150. Yuen MF, Wong DKH, Sablon E, Yuan HJ, Sum SM, Hui CK, Chan AOO,
Wong
 86 BCY Wong - 18 August, 2010

BCY, Lai CL. Hepatitis B virus genotypes B and C do not affect the anti-viral response
to lamivudine.
Antiviral Therapy 2003;8(6):531-534.
Impact Factor: 5.932 Citation: 39 Contribution: minor

151. Wong WM, Hui WM, Wong BCY.

GERD- an update
Medical Progress 2003; 30(10): 41-48.

152. Wong WM, Hui WM, Wong BCY

Non-erosive reflux disease-a distinct entity of Gastroesophageal reflux disease
Medical Progress 2003; 30(11): 41-46.

153. Fan XM, Tu SP, Lam SK, Wang WP, Wu J, Wong WM, Yuen MF, Lin MCM, Kung
HF, Wong BCY.
5-lipoxygenase-activating protein inhibitor MK-886 induces apoptosis in gastric cancer
through upregulation of p27 and Bax.
J Gastroenterol Hepatol 2004; 19(1): 31-37.
Impact Factor: 1.530 Citation: 20 Contribution: corresponding author

154. Wong BCY, Jiang XH, Lin MCM, Tu SP, Cui JT, Jiang SH, WM Wong, MF Yuen,
Lam SK, Kung HF.
Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun
NH2-terminal kinase
Gastroenterology 2004; 126(1): 136-47
Impact Factor: 12.718 Citation: 27 Contribution: first and corresponding
author

155. Wong BCY, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WHC,
Yuen ST, Leung SY, Fong DYT, Ho J, Ching CK, Chen JS and the China Gastric
Cancer Study Group
Helicobacter pylori eradication to prevent gastric cancer in a high-risk region in China:
A randomized controlled trial
JAMA 2004; 291(2): 187-194.
Impact Factor: 21.455 Citation: 316 Contribution: first and corresponding
author

156. Chan AO, Yuen MF, Lam CM, Fong CY, Wong BCY, Lai CL.
Prevalence and characteristics of familial hepatocellular carcinoma caused by
chronic hepatitis B infection in Hong Kong.
Aliment Pharmacol Ther 2004; 19(4): 401-6.
Impact Factor: 3.529 Citation: 1 Contribution: intermediate

157. Wong WM, Lai KC, Hui WM, Lam KF, Huang JQ, Hu WHC, Wong NYH, Lam CLK,
Xia HHX, Chan AOO, Lam SK, Wong BCY
 87 BCY Wong - 18 August, 2010

Double-blinded randomized controlled study to assess the effects of lansoprazole 30mg

and lansoprazole 15mg on 24-hour oesophageal and intragastric pH in Chinese subjects
with gastro-oesophageal reflux disease
Aliment Pharmacol Ther 2004; 19(4): 455-62.
Impact Factor: 3.529 Citation: 7 Contribution: corresponding author, first
author my Ph.D student

158. Ng FH, Wong BCY, Wong SY, Chen WH, Chang CM

Clopidogrel plus omeprazole compared with aspirin plus omeprazole for aspirin
induced symptomatic peptic ulcers/erosions with low to moderate bleeding/re-bleeding
risk – a single blinded randomized controlled study
Aliment Pharmacol Ther 2004; 19(3): 359-65
Impact Factor: 3.529 Citation: 21 Contribution: major

159. Hui CK, Lai KC, Yuen MF, Wong WM, Chan AO, Ng M, Chan CK, Cheung WW,
Lam SK, Lai CL, Wong BCY.
The role of cholecystectomy in reducing recurrent gallstone pancreatitis.
Endoscopy 2004; 36(3); 206-11.
Impact Factor: 3.227 Citation: 6 Contribution: corresponding author

160. Wong WM, Lam KF, Cheng C, Hui WM, Xia HH, Lai KC, Hu WHC, Huang JQ, Lam
CL, Chan CK, Chan AO, Lam SK, Wong BCY
Population based study of non-cardiac chest pain in Southern Chinese: Prevalence,
psychosocial factors and health care utilization
World J Gastroenterol 2004; 10(5): 707-712.
Impact Factor: 3.318 Citation: 31 Contribution: corresponding author, first
author my Ph.D student

161. Wong WM, Hui WM, Wong BC

Asia-Pacific consensus on gastroesophageal reflux disease
J Gastroenterol Hepatol 2004; 19(4):353-356. (Editorial)
Impact Factor: 1.796 Citation: 4 Contribution: corresponding author, first
author my Ph.D student

162. Xia HHX, Yang Y, Wong BCY.

Relationship between Helicobacter pylori infection and gastro-esophageal reflux
diseases.
Chinese Journal of Digestive Diseases 2004; 5: 1-6.
Citation: 1

163. Wong WM, Wong BCY.

Non-cardiac chest pain: an Asian view
Gastroenterol Clin N Am 2004; 33(1): 125-133.
Impact Factor: 1.684 Citation: 5 Contribution: corresponding author, first
author my Ph.D student

164. Wong WM, Cheng C, Wong BCY

 88 BCY Wong - 18 August, 2010

Constipation
Medical Progress 2004; 31(4): 201-7.

165. Hui CK, Liu CL, Lai KC, Chan SC, Hu WHC, Wong WM, Cheung WW, Lo CM, Fan
ST, Wong BCY
Outcome of emergency ERCP for acute cholangitis in patients 90 years of age and
older.
Aliment Pharmacol Ther 2004; 19(11): 1153-8.
Impact Factor: 3.981 Citation: 9 Contribution: corresponding author

166. Yuen MF, Tanaka Y, Mizokami M, Yuen JCH, Hui CK, Wong DKH, Yuan HJ, Sum
SM, Chan AOO, Wong BCY, Fan ST, Lai CL.
Role of hepatitis B virus genotypes Ba and C, core promoter and precore mutations on
hepatocellular carcinoma: a case control study
Carcinogenesis 2004; 25(9):1593 – 1598.
Impact Factor: 5.375 Citation: 32 Contribution: minor

167. Xia HHX, Lam SK, Huang XR, Wong WM, Leung SY, Yuen ST, Lan HY, Wong BCY.
Helicobacter pylori infection is associated with increased expression of macrophage
migration inhibitory factor by epithelial cells, T-cells and macrophages in gastric
mucosa.
J Infect Dis. 2004;190(2):293-302.
Impact Factor: 4.481 Citation: 12 Contribution: corresponding author

168. Xia HHX, Yang Y, Lam SK, Wong WM, Leung SY, Yuen ST, Elia G, Wright NA,
Wong BCY
Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter
pylori-infected gastric antrum, incisura and body and its association with antralization
J Clin Pathol 2004;57(8): 861-6.
Impact Factor: 2.549 Citation: 6 Contribution: corresponding author

169. Jiang XH, Tu SP, Cui JT, Lin MCM, Xia HHX, Wong WM, Chan AOO, Yuen MF,
Jiang SH, Lam SK, Kung HF, Soh JW, Weinstein IB, Wong BCY.
Antisense targeting protein kinase C  and 1 inhibits gastric carcinogenesis.
Cancer Research 2004; 64(16): 5787-94.
Impact Factor: 7.69 Citation: 23 Contribution: corresponding author, first
author my Ph.D student

170. Wong WM, Wong BCY.

Definition and diagnosis of gastro-oesophageal reflux disease.
J Gastroenterol Hepatol 2004; 19(S3), S26-32
Impact Factor: 1.796 Citation: 6 Contribution: corresponding author, first
author my Ph.D student

171. Wong WM, Lim P, Wong BCY.

 89 BCY Wong - 18 August, 2010

Clinical practice pattern of gastroenterologists, primary care physicians and

otolaryngologists for the management of GERD in the Asia-Pacific region – the FAST
survey.
J Gastroenterol Hepatol 2004;19(S3):S54-S60
Impact Factor: 1.796 Citation: 13 Contribution: corresponding author, first
author my Ph.D student

172. Gu Q, Xia HHX, Wang WH, Wang JD, Wong WM, Chan AOO, Yuen MF, Lam SK,
Cheung HKL, Liu XG, Wong BCY
Effect of cyclo-oxygenase inhibitors on Helicobacter pylori susceptibility to
metronidazole and clarithromycin
Aliment Pharmacol Ther 2004; 20: 675-681.
Impact Factor: 3.981 Citation: 5 Contribution: corresponding author, first
author my Ph.D student

173. Xia HHX, Zhang ST, Lam SK, Lin MCM, Kung HF, Wong BCY.
Expression of macrophage migration inhibitory factor in esophageal squamous cell
carcinoma and effects of bile acids and NSAIDs
Carcinogenesis 2005; 26(1): 11-15.
Impact Factor: 5.108 Citation: 4 Contribution: corresponding author

174. Yuen MF, Yuan HJ, Sablon E, Wong DKH, Hui CK, Chan AOO, Wong BCY, Lai CL.
Long-term follow-up study of Chinese patients with YMDD mutations: significance of
hepatitis B virus genotypes and characteristics of biochemical flares
J Clin Microbiol 2004 Sep;42(9):3932-6.
Impact Factor: 3.50 Citation: 10 Contribution: intermediate

175. Hui CK, Lai KC, Wong WM, Yuen MF, Ng M, Chan CK, Hu W, Cheung WW, Lai
CL, Wong BCY.
Outpatients undergoing therapeutic endoscopic retrograde cholangiopancreatography:
Six-hour versus overnight observation.
J Gastroenterol Hepatol 2004; 19(10):1163-1168.
Impact Factor: 1.796 Citation: 6 Contribution: corresponding author

176. Wong WM, Lai KC, Lam KF, Hui WM, Huang JQ, Xia HH, Hu WH, Lam CL, Chan
CK, Lam SK, Wong BCY.
Onset and disappearance of reflux symptoms in a Chinese population: a 1-year follow-
up study.
Aliment Pharmacol Ther. 2004 Oct 1;20(7):803-12.
Impact Factor: 3.981 Citation: 14 Contribution: corresponding author,
first author my Ph.D student

177. Xia HHX, Wong BCY, Zhang GS, Yang Y, Wyatt JM, Adams S, Cheung K, Lam SK,
Talley NJ.
Antralization of gastric incisura is topographically associated with increased gastric
epithelial apoptosis and proliferation, but not with CagA seropositivity
J Gastroenterol Hepatol 2004;19(11):1257-63.
 90 BCY Wong - 18 August, 2010

Impact Factor: 1.796 Citation: 2 Contribution: corresponding author

178. Lewis AE, Susarla R, Wong BC, Langman MJ, Eggo MC.
Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to
induce apoptosis in colon cancer line COLO 205.
Cell Signal 2005;17(2):253-262.
Impact Factor: 5.185 Citation: 13 Contribution: intermediate

179. Ding HG, Wand BE, Jia JD, Xia HHX, Wong BCY, Zhao CH, Xu YL.
Effects of octreotide on expression of L-type voltage-operated calcium channels and on
intracellular Ca2+ in activated hepatic stellate cells.
Chinese Medical Journal 2004; 117(6): 913-916.
Impact Factor: 0.182 Citation: 3 Contribution: intermediate

180. Kalia A, Mukhopadhyay AK, Dailide G, Ito Y, Azuma T, Wong BCY, Berg DE.
Evolutionary dynamics of insertion sequences in Helicobacter pylori.
J Bacteriol. 2004; 186(22): 7508-20.
Impact Factor: 4.175 Citation: 9 Contribution: intermediate

181. Yuen MF, Fung SK, Tanaka Y, Kato T, Mizokami M, Yuen JCH, Wong DKH, Yuan
HJ, Sum SM, Chan AOO, Wong BCY, Lai CL.
Longitudinal study of hepatitis activity and viral replication before and after HBeAg
seroconversion in chronic hepatitis B patients infected with genotypes B and C
J Clin Microbiol 2004 Nov; 42(11):5036-40.
Impact Factor: 3.50 Citation: 15 Contribution: intermediate

182. Wong WM, Lai KC, Hui WM, Hu WHC, Huang JQ, Wong NYH, Xia HHX, Chan
AOO, Lam SK, Wong BCY.
Pathophysiology of gastroesophageal reflux diseases in Chinese – role of transient
lower esophageal sphincter relaxation and esophageal motor dysfunction.
Am J Gastroenterol 2004; 99(11): 2088-93.
Impact Factor: 3.953 Citation: 12 Contribution: senior author, first
author my Ph.D student

183. Gu Q, Wang JD, Xia HHX, Lin MC, He H, Zou B, Tu SP, Yang Y, Liu XG, Lam SK,
Wong WM, Chan AOO, Yuen MF, Kung HF, Wong BCY.
Activation of Caspase-8/Bid and Bax pathways in aspirin-induced apoptosis in gastric
cancer.
Carcinogenesis 2005; 26(3):541-6.
Impact Factor: 5.108 Citation: 20 Contribution: corresponding author,
first author my Ph.D student

184. Huang JQ, Zheng GF, Chan GCF, Karlberg J, Lam SK, Wong BCY.
Efficacy of current antiemetic treatments for preventing delayed chemotherapy-induced
nausea and vomiting: a meta-analysis of randomized controlled trials.
Clinical Research and Regulatory Affairs 2004; 21(3&4): 191-212.
Impact Factor: 0.03 Citation: 1 Contribution: senior/last author
 91 BCY Wong - 18 August, 2010

185. Ye YN, Wu WKK, Shin, VY, Bruce IC, Wong BCY, Cho CH.
Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by
cigarette smoke.
Carcinogenesis 2005; 26: 827-834.
Impact Factor: 5.108 Citation: 27 Contribution: major

186. Wong WM, Xiao SD, Hu PJ, Wang WH, Gu Q, Huang JQ, Xia HHX, Wu SM, Li CJ,
Chen MH, Cui Y, Lai KC, Hu WHC, Chan CK, Lam SK, Wong BCY.
Standard treatment for Helicobacter pylori infection is sub-optimal in non-ulcer
dyspepsia compared to duodenal ulcer in Chinese
Aliment Pharmacol Ther 2005; 21(1): 73-81
Impact Factor: 3.529 Citation: 8 Contribution: corresponding author, first
author my Ph.D student

187. Ren Z, Borody T, Pang G, Dunkley M, Clancy R, Xia H, Chu KM, Wong J, Wong
BCY.
Evaluation of anti-Helicobacter pylori IgG2 antibody for the diagnosis of Helicobacter
pylori infection in western and Chinese populations
Aliment Pharmacol Ther 2005; 21(1): 83-89
Impact Factor: 3.529 Citation: 1 Contribution: senior/last author

188. Tu SP, Cui JT, Liston P, Xu R, Jiang XH, Lin MCM, Zhu YB, Zou B, Jiang SH, Wong
WM, Yuen MF, Lam SK, Kung HF, Wong BCY.
Gene therapy for colon cancer by adeno-associated viral vector-mediated transfer of
survivin Cys84Ala mutant
Gastroenterology 2005 Feb; 128(2): 361-75
Impact Factor: 13.440 Citation: 32 Contribution: corresponding author

189. Wong WM, Hui WM, Wong BCY.

Reply from authors-
J Gastroenterol Hepatol 2005 Mar; 20(3): 495.
Impact Factor: 1.504 Contribution: corresponding author, first
author my Ph.D student

190. Wong BCY.

Managing dyspepsia in regions with a high risk of gastric cancer
Aliment Pharmacol Ther 2005 Mar; 21 Suppl 1: 19-20
Impact Factor: 3.529 Contribution: corresponding author

191. Wong BCY, Chan AOO, Wong KW, Ching CK, Wong WM, Tam S, Lai KC, Chan CK,
Yuen MF, Lam SK.
A pilot study of participation in fecal occult blood test and screening colonoscopy after
health education in Hong Kong
Eur J Cancer Prev 2005 Apr; 14(2): 181-4.
Impact Factor: 1.673 Citation: 2 Contribution: corresponding author

192. Xia HHX, Lam SK, Lin MCM, Chan AOO, Kung HF, Ogura K, Berg BE, Wong BCY.
 92 BCY Wong - 18 August, 2010

Macrophage migration inhibitory factor stimulated by Helicobacter pylori increases

proliferation of gastric epithelial cells.
World J Gastroenterol 2005 Apr 7; 11(13): 1946-50
Impact Factor: 3.318 Citation: 7 Contribution: corresponding author

193. Yuen MF, Chow DHF, Tsui K, Wong BCY, Yuen JC, Wong DK, Lai CL.
Liver histology of Asian patients with chronic hepatitis B on prolonged lamivudine
therapy
Aliment Pharmacol Ther 2005; Apr 1; 21(7): 841-9
Impact Factor: 3.529 Citation: 3 Contribution: minor

194. Yuen MF, Wong DKH, Sum SM, Yuan HJ, Yuen JCH, Chan AOO, Wong BCY, Lai
CL.
Effect of Lamivudine therapy on the serum covalently closed circular (ccc) DNA of
chronic hepatitis B infection.
Am J Gastroenterol 2005; May: 100(5): 1099-1103.
Impact Factor: 3.953 Citation: 14 Contribution: minor

195. Yuen MF, Yuan HJ, Wong DKH, Yuen JCH, Wong WM, Chan AOO, Wong BCY, Lai
KC, Lai CL.
Prognostic determinants for chronic hepatitis B in Asians: therapeutic implications.
Gut 2005 Nov, 54(11): 1610-4.
Impact Factor: 6.323 Citation: 78 Contribution: minor

196. Huang JQ, Zheng GF, Hunt RH, Wong WM, Lam SK, Karlberg J, Wong BCY.
Do patients with non-ulcer dyspepsia respond differently to Helicobacter pylori
eradication treatments from those with peptic ulcer disease? A systematic review.
World J Gastroenterol 2005 May 14; 11(18):2726-32
Impact Factor: 3.318 Citation: 11 Contribution: corresponding author

197. Wong WM, Huang JQ, Xia HH, Fung FM, Tong TS, Cheung KL, Ho VY, Lai KC,
Chan CK, Chan AO, Hui CK, Lam SK, Wong BCY.
Low-dose rabeprazole, amoxicillin and metronidazole triple therapy for the treatment
of Helicobacter pylori infection in Chinese
J Gastroenterol Hepatol 2005 Jun;20(6):935-40.
Impact Factor: 1.504 Citation: 3 Contribution: corresponding author, first
author my Ph.D student

198. Wang WH, Huang JQ, Zheng GF, Wong WM, Lam SK, Karlberg J, Xia HH, Fass R,
Wong BCY.
Is PPI test a better diagnostic approach to non cardiac chest pain related to
gastroesophageal reflux? A meta-analysis.
Arch Intern Med 2005; 165: 1222-1228.
Impact Factor: 6.758 Citation: 39 Contribution: corresponding author

199. Chan AOO, Chu KM, Lam SK, Cheung KL, Law S, Kwok KF, Wong WM, Yuen MF,
Wong BCY.
 93 BCY Wong - 18 August, 2010

Early prediction of tumor recurrence after curative resection of gastric cancer by

measuring soluble E-cadherin.
Cancer 2005 Aug 15;104(4):740-6.
Impact Factor: 3.941 Citation: 10 Contribution: corresponding author

200. Wang WH, Huang JQ, Zheng GF, Xia HHX, Wong WM, Lam SK, Wong BCY.
Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the
treatment of erosive esophagitis: a meta-analysis
World J Gastroenterol 2005 Jul 14;11(26):4067-77.
Impact Factor: 3.318 Citation: 6 Contribution: corresponding author

201. Hui CK, Cheung WWW, Au WY, Lie AKW, Zhang HY, Yuen YH, Wong BCY,
Kwong YL, Liang R, Lau GKK
Hepatitis B reactivation after withdrawal of preemptive lamivudine in patients with
hematological malignancy upon completion of cytotoxic chemotherapy
Gut 2005 Nov; 54(11): 1597-603.
Impact Factor: 6.323 Citation: 41 Contribution: minor

202. Xia B, Xia HHX, Ma CW, Wong KW, Fung FMY, Hui CK, Chan CK, Chan AOO, Lai
KC,Yuen MF, Wong BCY.
Trends in the prevalence of peptic ulcer disease and Helicobacter pylori infection in family
physician-referred uninvestigated dyspeptic patients in Hong Kong
Aliment Pharmacol Ther 2005 Aug 1; 22(3): 243-9.
Impact Factor: 3.529 Citation: 9 Contribution: corresponding author

203. Liu CL, Fan ST, Lo CM, Tso WK, Wong Y, Poon RT, Lam CM, Wong BCY, Wong J.
Clinico-biochemical prediction of biliary cause of acute pancreatitis in the era of
endoscopic ultrasonography.
Aliment Pharmacol Ther 2005 Sep 1; 22(5): 423-31.
Impact Factor: 3.529 Citation: 7 Contribution: minor

204. Chan AOO, Lam KF, Hui WM, Hu WHC, Li J, Lai KC, Chan CK, Yuen MF, Lam SK,
Wong BCY.
Validated questionnaire on diagnosis and symptom severity for functional constipation
in the Chinese population
Aliment Pharmacol Ther 2005 Sep 1; 22(5): 483-8.
Impact Factor: 3.529 Citation: 4 Contribution: senior/last author

205. Yeung YP, Lo CM, Liu CL, Wong BC, Fan ST, Wong J.
Natural history of untreated nonsurgical hepatocellular carcinoma
Am J Gastroenterol 2005 Sep; 100(9): 1995-2004.
Impact Factor: 3.953 Citation: 16 Contribution: minor

206. Chan AOO, Cheng C, Hui WM, Hu WHC, Wong NY, Lam KF, Wong WM, Lai KC,
Lam SK, Wong BCY.
Differing coping mechanisms, stress level and anorectal physiology in patients with
functional constipation.
 94 BCY Wong - 18 August, 2010

World J Gastroenterol 2005; Sep 14; 11(34): 5362-6.

Impact Factor: 3.318 Citation: 3 Contribution: senior/last author

207. Fischbach W, Chan AO, Wong BCY.

Helicobacter pylori and gastric malignancy
Helicobacter 2005 Sept; 10 Supp 1: 34-9.
Impact Factor: 2.624 Citation: 10 Contribution: corresponding author

208. Winawer S, Faivre J, Selby J, Bertaro L, Chen TH, Kroborg O, Levin B, Mandel J,
O’Morain C, Richards M, Rennert G, Russo A, Saito H, Semigfnovsky B, Wong B,
Smith R.
Workgroup II: the screening process. UICC International Workshop on Facilitating
Screening for Colorectal Cancer, Oslo, Norway (29 and 30 June 2002).
Ann Oncol. 2005 Jan; 16(1):31-3.
Impact Factor: 4.335 Citation: 6 Contribution: minor

209. Fan XM, Zheng FS, Liu HY, Ma YH, Wong BC.
Mechanism of apoptosis induced by specific COX-2 inhibitor SC236 in gastric cancer
cells.
Zhonghua Zhong Liu Za Zhi. 2005 Mar; 27(3):145-7. Chinese.

210. Lai KC, Chu KM, Hui WM, Wong BC, Hu WH, Wong WM, Chan AO, Wong J, Lam
SK.
Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer
complications.
Am J Med 2005 Nov; 118(11): 1271-8.
Impact Factor: 4.179 Citation: 47 Contribution: minor

211. Wang J, He H, Yu L, Xia HH, Lin MC, Gu Q, Li M, Zou B, An X, Jiang B, Kung HF,
Wong BC.
Heat shock factor 1 (HSF1) downregulates X-linked inhibitor of apoptosis protein-
associated factor 1 (XAF1) through transcriptional regulation.
J Biol Chem 2006 Feb 3; 281(5): 2451-9. Epub 2005 Nov 21.
Impact Factor: 6.355 Citation: 11 Contribution: corresponding author

212. Xia HHX, He H, Wang JD, Gu Q, Lin MCM, Zou B, Yu LF, Sun YW, Chan AOO,
Kung HF, Wong BCY.
Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase
(JNK) inhibitor, SP-600125, in gastrointestinal cancers
Cancer Lett 2006; Sep 28 ;241(2): 268-274.
Impact Factor: 3.049 Citation: 8 Contribution: corresponding author

213. Wong BC
Introduction
J Gastroenterol Hepatol 2005 Dec 20; Suppl 3: S1.
Impact Factor: 1.504 Contribution: first and corresponding author
 95 BCY Wong - 18 August, 2010

214. Lim PW, Goh KL, Wong BC.

CYP2C19 genotype and the PPIs – focus on rabeprazole
J Gastroenterol Hepatol 2005 Dec 20; Suppl 3: S22-8.
Impact Factor: 1.504 Citation: 10 Contribution: senior/last author

215. Liu CL, Fan ST, Lo CM, Tso WK, Wong Y, Poon RT, Lam CM, Wong BC, Wong J
Comparison of early EUS and ERCP in the management of acute biliary pancreatitis: A
prospective randomized study
Clin Gastroenterol Hepatol 2005 Dec 3(12): 1238-44.
Impact Factor: 5.465 Citation: 22 Contribution: intermediate

216. Wong WM, Gu Q, Chu KM, Yee YK, Fung FMY, Tong TSM, Chan AOO, Lai KC,
Chan CK, Wong BCY.
Lansoprazole, levofloxacin and amoxicillin triple therapy vs quadruple therapy as
second-line treatment of resistant Helicobacter pylori infection
Aliment Pharmacol Ther 2006 Feb 1; 23(3): 421-7.
Impact Factor: 3.529 Citation: 19 Contribution: corresponding author, first
author my Ph.D student

217. Chan AOO, Peng JZ, Lam SK, Lai KC, Yuen MF, Cheung HK, Kwong YL, Rashid A,
Chan CK, Wong BCY.
Eradication of Helicobacter pylori infection reverses E-Cadherin promoter
hypermethylation.
Gut 2006 Apr;55(4):463-8.
Impact Factor: 9.002 Citation: 23 Contribution: corresponding author

218. Fass R, Wong BCY

Non cardiac chest pain and proton pump inhibitors. (Letter)
Arch Intern Med 2006 Jan 23, 166(2): 248-9.
Impact Factor: 7.92 Contribution: corresponding author

219. He H, Xia HHX, Wang JD, Gu Q, Lin MC, Zou B, Lam SK, Chan AOO, Yuen MF,
Kung HF, Wong BCY
Inhibition of human telomerase reverse transcriptase by non-steroidal anti-
inflammatory drugs in colon carcinoma
Cancer 2006 Mar 15; 106(6): 1243-9.
Impact Factor: 4.8 Citation: 3 Contribution: senior/last author, first
author my Ph.D student

220. Li GQ, Xia HHX, Chen MH, Gu Q, Wang JD, Peng JZ, Chan AOO, Cho CH, So HL,
Lam SK, Hu PJ, Liang YJ, Lin HL, Berg DE, Feng ZH, Langenbach R, Wong BCY
Effects of cyclooxygenase-1 and -2 gene disruption on Helicobacter pylori-induced
gastric inflammation
J Infect Dis 2006 Apr 1; 193(7): 1037-46.
Impact Factor: 4.943 Citation: 7 Contribution: corresponding author
 96 BCY Wong - 18 August, 2010

221. Wang J, Peng Y, Sun YW, He H, Zhu S, An X, Li M, Lin MCM, Zou B, Xia HHX,
Jiang B, Chan AO, Yuen MF, Kung HF, Wong BCY.
All-trans retinoic acid induces XAF1 expression through an interferon regulatory
factor-1 element in colon cancer
Gastroenterology 2006 Mar; 130(3): 747-758.
Impact Factor: 12.457 Citation: 16 Contribution: corresponding author

222. Wong BCY, Kinoshita Y.

Systematic review on epidemiology of gastro-oesophageal reflux disease in Asia.
Clin Gastroenterol Hepatol 2006 Apr 4; (4): 398-407
Impact Factor: 5.465 Citation: 30 Contribution: first and corresponding
author

223. Fan XM, Jiang XH, Gu Q, Ching YP, He H, Xia HH, Lin MC, Chan AO, Yuen MF,
Kung HF, Wong BCY.
Inihibition of Akt/PKB by a COX-2 inhibitor induces apoptosis in gastric cancer
Digestion 2006; June 20, 73 (2-3): 75-8
Impact Factor: 1.826 Citation: 5 Contribution: corresponding author

224. Jiang Y, Xia B, Jiang L, Lv M, Guo Q, Chen M, Li J, Xia HH, Wong BC.
Association of CTLA-4 gene microsatellite polymorphism with ulcerative colitis in
Chinese patients.
Inflamm Bowel Dis. 2006 May; 12(5): 369-373.
Impact Factor: 3.545 Citation: 8 Contribution: senior/last author

225. Wong BCY, Chan AOO, Wong WM, Hui WM, Kung HF, Lam SK.
Attitudes and knowledge of colorectal cancer and screening in Hong Kong – A
population-based study
J Gastroenterol Hepatol 2006 Feb;21(1Pt1):41-6.
Impact Factor: 1.785 Citation: 5 Contribution: first and corresponding
author

226. Chan AO, Hui WM, Chan CK, Lai KC, Hu WH, Yuen MF, Wong WM, Lau GK, Hui
CK, Lam SK, Wong BC.
Colonoscopy demand and practice in a regional hospital over 9 years in Hong Kong:
Resource implication for cancer screening
Digestion 2006 Jun 20:73(2-3): 84-88.
Impact Factor: 1.826 Citation: 2 Contribution: corresponding author

227. Gu Q, Xia HH, Wang JD, Wong WM, Chan AO, Lai KC, Chan CK, Yuen MF, Fung
FM, Wong KW, Lam SK, Wong BC.
Update on clarithromycin resistance in Helicobacter pylori in Hong Kong and its effect
on clarithromycin-based triple therapy.
Digestion 2006 Jun 20:73(2-3) 101-106.
Impact Factor: 1.826 Citation: 2 Contribution: corresponding author,
first author my Ph.D student

228. Lai KC, Chu KM, Hui WM, Wong BC, Hung WK, Loo CK, Hu WH, Chan AO,
 97 BCY Wong - 18 August, 2010

Kwok KF, Fung TT, Wong J, Lam SK.

Esomeprazole with aspirin versus clopidogrel for prevention of recurrent
gastrointestinal ulcer complications
Clin Gastroenterol Hepatol 2006 Jul; 4(7): 860-5. Epub 2006 Jun 22.
Impact Factor: 5.465 Citation: 21 Contribution: intermediate

229. Chan AO, Lam KF, Tong T, Siu DC, Jim MH, Hui WM, Lai KC, Yuen MF, Lam SK,
Wong BC
Coexistence between colorectal cancer/adenoma and coronary artery disease: results
from 1382 patients.
Aliment Pharmacol Ther 2006 Aug 1; 24(3): 535-9.
Impact Factor: 3.287 Citation: 4 Contribution: senior/last author

230. Cheung TK, Lai CL, Wong BC, Fung J, Yuen MF

Clinical features, biochemical parameters, and virological profiles or patients with
hepatocellular carcinoma in Hong Kong
Aliment Pharmacol Ther 2006 Aug; 24(4): 573-583.
Impact Factor: 3.287 Citation: 1 Contribution: intermediate, first author
my Ph.D student

231. Ho KY, Cheung TK, Wong BC

Gastroesophageal reflux disease in Asian countries: disorder of nature or nurture?
J Gastroenterol Hepatol 2006 Sept;21(9): 1362-5.
Impact Factor: 1.785 Citation: 2 Contribution: senior/last author

232. Chan AO, Huang C, Hui WM, Cho CH, Yuen MF, Lam SK, Rashid A, Wong BC.
Stability of E-cadherin methylation status in gastric mucosa associated with histology
changes.
Aliment Pharmacol Ther 2006 Sep 1;24(5):831-6.
Impact Factor: 3.287 Citation: 3 Contribution: senior/last author

233. Hu WH, Lam SK, Lam CL, Wong WM, Lam KF, Lai KC, Wong YH, Wong BC, Chan
AO, Chan CK, Leung GM, Hui WM.
Comparison between empirical prokinetics, Helicobacter test-and-treat and empirical
endoscopy in primary-care patients presenting with dyspepsia: a one-year study.
World J Gastroenterol 2006 Aug 21:12(31):5010-6.
Citation: 2 Contribution: intermediate

234. Yuen MF, Tam S, Fung J, Wong DK, Wong BCY, Lai CL
Traditional Chinese medicine causing hepatotoxicity in patients with chronic hepatitis
B infection: a one-year prospective study
Aliment Pharmacol Ther 2006 Oct 15;24(8):1179-86.
Impact Factor: 3.287 Citation: 8 Contribution: intermediate

235. Chan AO, Hui WM, Lam KF, Leung G, Yuen MF, Lam SK, Wong BC
Familial aggregation in constipated subjects in a tertiary referral center
Am J Gastroenterol 2007 Jan; 102(1):149-52.
 98 BCY Wong - 18 August, 2010

Impact Factor: 5.116 Citation: 1 Contribution: senior/last author

236. Zou B, Chim CS, Zeng H, Leung SY, Yang Y, Tu SP, Lin MC, Wang J, He H, Jiang
SH, Sun YW, Yu LF, Yuen ST, Kung HF, Wong BC.
Correlation between the single site CpG and expression silencing of the XAF1 gene in
human gastric and colon cancers
Gastroenterology 2006 Dec 131(6): 1835-43.
Impact Factor: 12.457 Citation: 15 Contribution: corresponding author

237. Cheung TK, Wong BC

Proton pump inhibitor failure/resistance: Proposed mechanisms and therapeutic
algorithm.
J Gastroenterol Hepatol 2006 Dec 21(S5): S119-S124.
Impact Factor: 1.785 Contribution: corresponding author, first
author my Ph.D student

238. Tang LP, Cho CH, Hui WM, Huang C, Chu KM, Xia HH, Lam SK, Rashid A, Wong
BC, Chan AO.
An inverse correlation between interleukin-6 and select gene promoter methylation in
patients with gastric cancer.
Digestion 2006 Nov 30; 74(2): 85-90.
Impact Factor: 1.826 Citation: 4 Contribution: minor

239. Zhang MJ, He LH, Wong BC, Zhou ZF, Zhang JZ.
Distribution of cagA 3’ region, iceA, vacA and HP0519 on Helicobacter pylori isolates
from China.
Zhonghua Liu Xing Bing Xue Za Zhi 2006 Jun; 27(6):508-12. Chinese

240. Wang WH, Huang JQ, Zheng GF, Xia HH, Wong WM, Liu XG, Karlberg J, Wong BC.
Effects of proton-pump inhibitors on functional dyspepsia: A meta-analysis of
randomized placebo-controlled trials.
Clin Gastroenterol Hepatol 2007 Feb;5(2):178-85.
Impact Factor: 5.465 Citation: 11 Contribution: corresponding author

241. Wong WM, Lai KC, Yiu WC, Wong BC, Chan FL, Lai CL.
Intestinal tuberculosis mimicking fistulizing Crohn’s disease.
J Gastroenterol Hepatol 2007 Jan; 22(1): 137-9.
Impact Factor: 1.785 Contribution: minor, first author my
Ph.D student

242. Chan AO, Lam KF, Hui WM, Leung G, Wong NY, Lam SK, Wong BC
Influence of positive family history on clinical characteristics of functional constipation.
Clin Gastroenterol Hepatol 2007 Feb; 5(2): 197-200.
Impact Factor: 5.465 Citation: 1 Contribution: senior/last author

243. Cheung TK, Xia HH, Wong BC

Helicobacter pylori eradication for gastric cancer prevention.
 99 BCY Wong - 18 August, 2010

J Gastroenterol 2007 Jan; 42 Suppl 17:10-5.

Impact Factor: 1.532 Citation: 2 Contribution: corresponding author,
first author my Ph.D student

244. Chan AO, Hui WM, Leung G, Hu WH, Lam SK, Wong BC.
Efficacy of tegaserod for functional constipation in Chinese subjects: a randomized
double-blind controlled trial in a single center.
Aliment Pharmacol Ther 2007 Feb 15; 25(4): 463-9.
Impact Factor: 3.287 Citation: 2 Contribution: senior/last author

245. Yuen MF, Sablon E, Libbrecht E, van de Velde H, Wong DK, Fung J, Wong BC, Lai
CL
Significance of viral load, core promoter/ precore mutations and specific sequences of
polymerase gene in HBV-infected patients on three-year lamivudine treatment
Antivir Ther 2006;11(6): 779-86.
Impact Factor: 5.286 Citation: 6 Contribution: intermediate

246. Chan AO, Hui WM, Leung G, Tong T, Hung I, Chan P, Hsu A, But D, Wong BC, Lam
SK, Lam KF.
Patients with functional constipation do not have increased prevalence of colorectal
cancer precursors.
Gut 2007 Mar; 56(3): 451-2.
Impact Factor: 9.002 Citation: 2 Contribution: intermediate

247. Yuen MF, Wong DKH, Zheng BJ, Chan CCS, Yuen JCH, Wong BCY, Lai CL.
Difference in T helper responses during hepatitis flares in HBeAg-positive patients
with genotypes B and C: Implication for early HBeAg seroconversion.
J Viral Hepatol 2007 Apr; 14:269-275
Impact Factor: 3.290 Citation: 5 Contribution: intermediate

248. Wang J, Yang Y, Xia HH, Gu Q, Lin MC, Jiang B, Peng Y, Li G, An X, Zhang Y,
Zhuang Z, Zhang Z, Kung HF, Wong BCY.
Suppression of FHL2 expression induces cell differentiation and inhibits gastric and
colon carcinogenesis
Gastroenterology 2007 Mar; 132(3): 1066-76.
Impact Factor: 12.457 Citation: 7 Contribution: corresponding author

249. Yu LF, Wang J, Zou B, Lin MC, Wu YL, Xia HHX, Sun YW, Gu Q, He H, Lam SK,
Kung HF, Wong BCY.
XAF1 mediates apoptosis through extracellular signal regulated kinase pathway in
colon cancer
Cancer 2007 May 15;109(10):1996-2003.
Impact Factor: 4.582 Citation: 5 Contribution: corresponding author

250. Cheung TK, Lim PW, Wong BC.

Noncardiac chest pain- An Asia-Pacific survey on the views of primary care physicians.
 100 BCY Wong - 18 August, 2010

Dig Dis Sci. 2007 Nov;52(11):3043-8.

Impact Factor: 1.528 Citation: 3 Contribution: corresponding author, first
author my Ph.D student

251. Cheung TK, Lam KF, Hu WH, Lam CL, Wong WM, Hui WM, Lai KC, Lam SK,
Wong BCY.
Positive association between gastro-esophageal reflux disease and irritable bowel
syndrome in a Chinese population.
Aliment Pharmacol Ther 2007 May; 25(9): 1099-1104.
Impact Factor: 3.287 Contribution: corresponding author, first
author my Ph.D student

252. Ge R, Sun X, Gu Q, Watt RM, Tanner JA, Wong BC, Xia HH, Huang JD, He QY, Sun
H.
A proteomic approach for the identification of bismuth-binding proteins in
Helicobacter pylori.
J Biol Inorg Chem. 2007 Aug; 12(6):831-42.
Impact Factor: 3.303 Citation: 3 Contribution: minor

253. Ng SS, Cheung YT, An XM, Chen YC, Li M, Li GH, Cheung W, Sze J, Lai L, Peng Y,
Xia HH, Wong BC, Leung SY, Xie D, He ML, Kung HF, Lin MC.
Cell Cycle-related kinase: a novel candidate oncogene in human glioblastoma.
J Natl Cancer Inst 2007 Jun 20; 99(12):936-48.
Impact Factor: 15.271 Citation: 2 Contribution: minor

254. Chey WD, Wong BC, Practice Parameters Committee of the American College of
Gastroenterology.
American College of Gastroenterology Guideline on the management of Helicobacter
pylori infection.
Am J Gastroenterol 2007 Aug; 102(8): 1808-25.
Impact Factor: 5.608 Citation: 47 Contribution: senior/last author

255. Lam TJ, Wong BC, Mulder CJ, Pena AS, Hui WM, Lam SK, Chan AO.
Increasing prevalence of advanced colonic polyps in young patients undergoing
colonoscopy in a referral academic hospital in Hong Kong.
World J Gastroenterol 2007 Jul 28; 13(28): 3873-7.
Citation: 1 Contribution: intermediate

256. Cheung TK, Lim PW, Wong BC.

The view of gastroenterologists on non-cardiac chest pain in Asia.
Aliment Pharmacol Ther 2007 Aug 15; 26(4): 597-603.
Impact Factor: 3.287 Citation: 2 Contribution: corresponding author, first
author my Ph.D student

257. Cheung TK, Wong WM, Wong NY, Chan CK, Fung J, Yuen MF, Chan AO, Tong TS,
Wong BC.
 101 BCY Wong - 18 August, 2010

Symptom resolution does not predict healing of erosive oesophagitis in Chinese.

Digestion 2007 Jul 2; 75(2-3): 128-134
Impact Factor: 1.826 Citation: 1 Contribution: corresponding author,
first author my Ph.D student

258. Farrell GC, Desmond PV, Wong BC; the Editors of Journal of Gastroenterology and
Hepatology.
Agent Orange: Your new look JGH (the improvements go deeper than the cover)
J Gastroenterol Hepatol 2007 Aug; 22(8): 1167-8.
Impact Factor: 1.785 Citation: 2 Contribution: major

259. Yee YK, Cheung TK, Chu KM, Chan CK, Fung J, Chan P, But D, Hung I, Chan AO,
Yuen MF, Hsu A, Wong BC.
Clinical trial: Levofloxacin-based quadruple therapy was inferior to traditional
quadruple therapy in the treatment of resistant Helicobacter pylori infection.
Aliment Pharmacol Ther. 2007 Oct 1; 26(7):1063-7.
Impact Factor: 3.287 Citation: 2 Contribution: corresponding author,
first author my Ph.D student

260. Chan AO, Jim MH, Lam KF, Morris JS, Siu DC, Tong T, Ng FH, Wong SY, Hui WM,
Chan CK, Lai KC, Cheung TK, Chan P, Wong G, Yuen MF, Lau YK, Lee S, Szeto ML,
Wong BC, Lam SK.
Prevalence of colorectal neoplasm among patients with newly diagnosed coronary
artery disease. JAMA 2007 Sept 26; 298(12): 1412-9.
Impact Factor: 23.175 Citation: 5 Contribution: major

261. Zou B, Wong BC

Do serrated adenomas have higher malignant potential than traditional adenomas?
J Gastroenterol Hepatol 2007 Nov 22(11): 1701-3. Editorial
Impact Factor: 1.785 Contribution: corresponding author

262. Sun Y, Qiao L, Xia HH, Lin MC, Zou B, Yuan Y, Zhu S, Gu Q, Cheung TK, Kung HF,
Yuen MF, Chan AO, Wong BC.
Regulation of XAF1 expression in human colon cancer cell by interferon beta:
Activation by the transcription regulator STAT1.
Cancer Lett. 2008 Feb 18;260(1-2):62-71.
Impact Factor: 3.277 Contribution: corresponding author

263. Yee YK, Cheung T, Chan AO, Yuen M, Wong BC.

Decreasing trend of esophageal adenocarcinoma in Hong Kong.
Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2637-40.
Impact Factor: 4.289 Contribution: corresponding author,
first author my Ph.D student

264. Liu ES, Ye YN, Shin VY, Wu WK, Wong BC, Cho CH.
 102 BCY Wong - 18 August, 2010

Interaction of cigarette smoking with cyclooxygenase-2 on ulcerative colitis-associated

neoplasia in mice.
Cancer Invest. 2007 Dec;25(8):750-7.
Impact Factor: 2.106 Citation: 4 Contribution: intermediate

265. Yuen MF, Seto WK, Chow DH, Tsui K, Wong DK, Ngai VW, Wong BC, Fung J,
Yuen JC, Lai CL.
Long-term lamivudine therapy reduces the risk of long-term complications of chronic
hepatitis B infection even in patients without advanced disease.
Antivir Ther. 2007;12(8):1295-303.
Impact Factor: 4.547 Citation: 9 Contribution: intermediate

266. Fock KM, Talley NJ, Fass R, Goh KL, Katelaris P, Hunt R, Hongo M, Ang TL,
Holtmann G, Nandurkar S, Lin SR, Wong BC, Chan FK, Rani AA, Bak YT, Sollano J,
Ho KY, Manatsathit S.
Asia-Pacific consensus on the management of gastroesophageal reflux disease: update.
J Gastroenterol Hepatol. 2008 Jan;23(1):8-22.
Impact Factor: 1.673 Citation: 8 Contribution: intermediate

267. Ng FH, Wong SY, Lam KF, Chang CM, Lau YK, Chu WM, Wong BC.
Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel,
and enoxaparin in acute coronary syndrome.
Am J Gastroenterol. 2008 Apr; 103(4): 865-71.
Impact Factor: 5.608 Citation: 6 Contribution: senior/last author

268. Li GQ, Xia HH, Chen MH, Tsukamoto T, Tatematsu M, Gu Q, Qiao L, Cho CH, So
WH, Yuen MF, Hu PJ, Liang YJ, Lin HL, Chan AO, Wong BC.
Effects of aspirin on the development of Helicobacter pylori-induced gastric
inflammation and heterotopic proliferative glands in Mongolian gerbils.
Helicobacter. 2008 Feb;13(1):20-9.
Impact Factor: 2.423 Citation: 1 Contribution: corresponding author

269. Cheung TK, Wong BC.

Treatment of Helicobacter pylori and prevention of gastric cancer.
J Dig Dis. 2008 Feb;9(1):8-13.
Citation: 2 Contribution: corresponding author,
first author my Ph.D student

270. Cheung TK, Wong BC, Lam SK.Gastro-oesophageal reflux disease in Asia: birth of a
'new' disease?
Drugs. 2008;68(4):399-406.
Impact Factor: 3.726 Contribution: corresponding author,
first author my Ph.D student

271. Dai Y, Qiao L, Chan K, Zou B, Ma J, Lan H, Gu Q, Li Z, Wang Y, Wong B, Wong BC.
 103 BCY Wong - 18 August, 2010

Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in

vivo. Int J Cancer. 2008 Jun 15;122(12):2858-63.
Impact Factor: 4.555 Citation: 3 Contribution: senior/last author

272. Sun Y, Qiao L, Zou B, Xia HH, Gu Q, Ma J, Lin MC, Zhu Q, Zhu S, Dai Y, Wong BC.
Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in
colon cancer cells.
Digestion. 2008;77(2):79-86.
Impact Factor: 2.097 Contribution: corresponding author

273. Yau T, Chan P, Ching Chan Y, Wong BC, Liang R, Epstein RJ.
Review article: current management of metastatic colorectal cancer - the evolving
impact of targeted drug therapies.
Aliment Pharmacol Ther. 2008 Jun 1;27(11):997-1005.
Impact Factor: 3.71 Contribution: intermediate

274. Tulassay Z, Stolte M, Sjölund M, Engstrand L, Butruk E, Malfertheiner P, Dite P,

Tchernev K, Wong BC, Gottlow M, Eklund S, Wrangstadh M, Nagy P.
Effect of esomeprazole triple therapy on eradication rates of Helicobacter pylori,
gastric ulcer healing and prevention of relapse in gastric ulcer patients.
Eur J Gastroenterol Hepatol. 2008 Jun;20(6):526-36.
Impact Factor: 1.83 Citation: 2 Contribution: intermediate

275. Qiao L, Dai Y, Gu Q, Chan KW, Ma J, Lan HY, Zou B, Rocken C, Ebert MP,
Wong BC.
Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor
effects of troglitazone and 15-PGJ2.
Cancer Lett. 2008 Sep 18;268(2):260-71.
Impact Factor: 3.398 Citation: 1 Contribution: corresponding author

276. Ma J, Chen MH, Wang J, Xia HH, Zhu SL, Liang Y, Gu Q, Qiao L, Dai Y, Zou
B, Li Z, Zhang Y, Lan HY, Wong BC.
Pancreatic-duodenal homeobox 1 (PDX1) functions as a tumor suppressor in gastric
cancer.
Carcinogenesis. 2008 Jul;29(7):1327-33.
Impact Factor: 5.406 Contribution: corresponding author

277. Qiao L, Gu Q, Dai Y, Shen Z, Liu X, Qi R, Ma J, Zou B, Li Z, Lan HY, Wong

BC.
XIAP-Associated Factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.
Tumour Biol. 2008 Jun 11;29(2):122-129.
Impact Factor: 2.481 Contribution: corresponding author

278. Ng FH, Lam KF, Wong SY, Chang CM, Lau YK, Yuen WC, Chu WM, Wong
BC.
Upper gastrointestinal bleeding in patients with aspirin and clopidogrel co-therapy.
Digestion. 2008 Jun 25;77(3-4):173-177.
 104 BCY Wong - 18 August, 2010

Impact Factor: 2.097 Contribution: senior/last author

279. Cheung TK, Lim PW, Wong BC.

Noncardiac chest pain-an asia-pacific survey on the role of the cardiologist.
J Clin Gastroenterol. 2008 Nov-Dec; 42(10):1116-7.
Impact Factor: 2.938 Contribution: corresponding author, first
author my Ph.D student

280. He QY, Yang H, Wong BC, Chiu JF.

Serological proteomics of gastritis: degradation of apolipoprotein a-i and alpha1-
antitrypsin is a common response to inflammation irrespective of Helicobacter pylori
infection.
Dig Dis Sci. 2008 Dec; 53(12): 3112-8.
Impact Factor: 1.319 Contribution: intermediate

281. Li M, Wang J, Ng SS, Chan CY, Chen AC, Xia HP, Yew DT, Wong BC, Chen Z,
Kung HF, Lin MC.
The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated
with oncogenic activities.
Glia. 2008 Sep; 56(12):1328-38.
Impact Factor: 5.38 Contribution: intermediate

282. Qiao L, Dai Y, Gu Q, Chan KW, Zou B, Ma J, Wang J, Lan HY, Wong BC.
Down-regulation of XIAP synergistically enhanced peroxisome proliferator-activated
receptor {gamma} ligand-induced growth inhibition in colon cancer.
Mol Cancer Ther. 2008 Jul; 7(7):2203-11.
Impact Factor: 4.8 Contribution: corresponding author

283. Feng GS, Ma JL, Wong BC, Zhang L, Liu WD, Pan KF, Shen L, Zhang XD, Li J,
Xia HH, Li JY, Lam SK, You WC.
Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial
for gastric cancer prevention.
World J Gastroenterol. 2008 Jul 28;14(28):4535-9.
Contribution: intermediate

284. Cheung TK, Hou X, Lam KF, Chen J, Wong WM, Cha H, Xia HH, Chan AO,
Tong TS, Leung GY, Yuen MF, Wong BC.
Quality of life and psychological impact in patients with noncardiac chest pain.
J Clin Gastroenterol. 2008 Aug 11 epub
Impact Factor: 2.938 Contribution: corresponding author, first
author my Ph.D student

285. Qiao L, Li GH, Dai Y, Wang J, Li Z, Zou B, Gu Q, Ma J, Pang R, Lan HY,

Wong BC.
Gene expression profile in colon cancer cells with respect to XIAP expression status.
Int J Colorectal Dis. 2009 Mar; 24(3): 245-60. 2008 Aug 13 epub
Impact Factor: 1.918 Contribution: corresponding author
 105 BCY Wong - 18 August, 2010

286. Zhuang ZH, Tsao SW, Deng W, Wang JD, Xia HH, He H, Feng HC, Wang LD,
Gu Q, Lam SK, Lin MC, Kung HF, Wong BC.
Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and
telomerase-induced immortalization of human esophageal epithelial cells.
J Gastroenterol Hepatol. 2008; Oct; 23(10): 1613-1620.
Impact Factor: 1.673 Contribution: corresponding author

287. Qiao L, Wang Y, Pang R, Wang J, Dai Y, Ma J, Gu Q, Li Z, Zhang Y, Zou B,

Lan HY, Wong BC.
Oncogene functions of FHL2 are independent from NF-kappaB 1 alpha in
gastrointestinal cancer.
Pathol Oncol Res. 2009 Mar; 15(1): 31-6.
Impact Factor: 1.272 Contribution: corresponding author

288. Zhu S, Xia HH, Yang Y, Ma J, Chen M, Hu P, Gu Q, Liang Y, Lin H, Wong C.

Alterations of gastric homeoprotein expression in Helicobacter pylori infection,
incisural antralisation, and intestinal metaplasia.
Dig Dis Sci. 2009 May; 54(5): 996-1002.
Impact Factor: 1.379 Contribution: corresponding author

289. Ng FH, Chan P, Kwan CP, Loo CK, Cheung TK, Wong SY, Kng C, Ng KM, Lai
ST, Wong BC.
Management and outcome of peptic ulcers or erosions in patients receiving a
combination of aspirin plus clopidogrel.
J Gastroenterol 2008; 43(9): 679-86.
Impact Factor: 2.052 Contribution: senior/last author

290. Yee YK, Cheung TK, Gu Q, Chan P, But D, Hung IF, Chan CK, Yuen MF,
Wong BC.
Factors affecting physicians' practices related to Helicobacter pylori infection: effect of
experience and mode of practice.
Digestion. 2008 Oct 24;78(2-3):77-81.
Impact Factor: 2.097 Contribution: corresponding author,
first author my Ph.D student

291. Yuen MF, Tanaka Y, Fong DY, Fung J, Wong DK, Yuen JC, But DY, Chan AO,
Wong BC, Mizokami M, Lai CL.
Independent risk factors and predictive score for the development of hepatocellular
carcinoma in chronic hepatitis B.
J Hepatol. 2009 Jan; 50(1):80-8.
Impact Factor: 6.642 Contribution: intermediate

292. Wang J, Zhang W, Zhang Y, Chen Y, Zou B, Jiang B, Pang R, Gu Q, Qiao L,

Lan H, Kung HF, Wong BC.
c-jun NH2-terminal Kinase (JNK1) upregulates XIAP-associated Factor 1 (XAF1)
through Interferon Regulatory Factor 1 (IRF-1) in gastrointestinal cancer.
 106 BCY Wong - 18 August, 2010

Carcinogenesis. 2009 Feb; 30(2):222-9.

Impact Factor: 5.406 Contribution: corresponding author

293. Cheung TK, Lam B, Lam KF, Ip M, Ng C, Kung R, Wong BC.

Gastroesophageal reflux disease is associated with poor asthma control, quality of life,
and psychological status in chinese asthma patients.
Chest. 2009 May; 135(5): 1181-5. Epub 2008 Dec 31.
Impact Factor: 4.143 Contribution: corresponding author,
first author my Ph.D student

294. Yee YK, Wong BC.

Adenocarcinoma of the esophagogastric junction: do we see more or less?
J Gastroenterol Hepatol. 2008 Nov;23(11):1627-8.
Impact Factor: 1.673 Contribution: corresponding author,
first author my Ph.D student

295. Cheung TK, Lam PK, Wei WI, Wong WM, Ng ML, Gu Q, Hung IF, Wong BC.
Quality of life in patients with laryngopharyngeal reflux.
Digestion. 2009; 79((1): 52-57.
Impact Factor: 2.097 Contribution: corresponding author,
first author my Ph.D student

296. Qiao L, Wong BC.

Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Drug Resist Updat. 2009 June; 12: 55-64. Epub Mar 9
Impact Factor: 6.435 Contribution: corresponding author

297. Wong BL, Zhu SL, Huang XR, Ma J, Xia HH, Bucala R, Wong BC, Lan HY.
Essential role for macrophage migration inhibitory factor in gastritis induced by
Helicobacter pylori.
Am J Pathol. 2009 Apr; 174(4): 1319-28.
Impact Factor: 5.487 Contribution: intermediate, first
author my Ph.D student

298. Tan VP, Wong BC.

Non-cardiac chest pain in Asia: time for a consensus.
J Gastroenterol Hepatol. 2009 Feb; 24(2):178-9.
Impact Factor: 1.673 Contribution: corresponding author

299. Xiao YL, Lin JK, Cheung TK, Wong NY, Yang L, Hung IF, Wong BC, Chen
MH.
Normal values of 24-Hour combined esophageal multichannel intraluminal impedance
and pH monitoring in the chinese population.
Digestion. 2009; 79(2): 109-114.
Impact Factor: 2.097 Contribution: corresponding author
 107 BCY Wong - 18 August, 2010

300. Tu SP, Liston P, Cui JT, Lin MC, Jiang XH, Yang Y, Gu Q, Jiang SH, Lim CT,
Kung HF, Korneluk RG, Wong BC.
Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric
cancer.
Int J Cancer. 2009 Jan 22, 125(3): 688-97. Epub Jan.
Impact Factor: 4.555 Contribution: corresponding author

301. Hung IFN, Wong BCY

Assessing the risks and benefits of treating Helicobacter pylori infection.
Therapeutic Advances in Gastroenterology 2009 May 2(3): 141-147.
Contribution: corresponding author

302. Dai Y, Qiao L, Chan KW, Yang M, Ye J, Ma J, Zou B, Gu Q, Wang J, Pang R,

Lan HY, Wong BC.
Peroxisome proliferator-activated receptor-{gamma} contributes to the inhibitory
effects of embelin on colon carcinogenesis.
Cancer Research 2009 Jun 1; 69(11): 4776-83. Epub May 19
Impact Factor: 7.672 Contribution: senior/last author

303. Tu S, Sun R, Lin MC, Cui JT, Zou B, Gu Q, Kung HF, Che CM, Wong BC
Gold (III) porphyrin complexes induce apoptosis and cell cycle arrest and inhibit tumor
growth in colon cancer.
Cancer. 2009 Jul 1;115(19):4459-4469.
Impact Factor: 5.238 Contribution: corresponding
author

304. Tan VP, Wong BC

A false sense of security: symptom control does not predict healing of esophagitis on
proton pump inhibitors
Aliment Pharmacol Ther 2009 Aug;30(3): 307-8.
Impact Factor: 3.71 Contribution: corresponding author

305. Wang J, Gu Q, Li M, Zhang W, Yang M, Zou B, Chan S, Liang Q, Jiang B, Tu S,

Ma J, Hung IF, Lan H, Wong BC.
Identification of XAF1 as a novel cell cycle regulator through modulating G2/M
checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer
Carcinogenesis 2009 Sep; 30(9): 1507-16. Epub 2009 Jul 23
Impact Factor: 5.406 Contribution: corresponding
author

306. Xiao YL, Lin JK, Cheung TK, Wong NY, Hung IF, Wong BC, Peng S, Wang AJ,
Chen MH.
Reflux profile of Chinese gastroesophageal reflux disease patients with combined
multichannel intraluminal impedance-pH monitoring
J Gastroenterol Hepatol 2009 Jun; 24(6): 1113-8.
Impact Factor: 1.673 Contribution: minor
 108 BCY Wong - 18 August, 2010

307. Yee YK, Wong KW, Hui CK, Chan CK, Chan AO, Lam SK, Wong BC.
Prevalence and time trend of intestinal metaplasia in Hong Kong.
J Gastroenterol Hepatol 2009 May; 24(5): 896-899.
Impact Factor: 1.673 Contribution: corresponding
author

308. Tan VP, Wong BC

Management of acute peptic ulcers: how ethnicity , different proton pump inhibitors
and mechanisms of delivery alter the equation.
J Gastroenterol Hepatol 2009 Jul; 24(7): 1157-8.
Impact Factor: 1.673 Contribution: corresponding
author

309. Xia HH, Yang Y, Chu KM, Gu Q, Zhang YY, He H, Wong WM, Leung SY,
Yuen ST, Yuen MF, Chan AO, Wong BC.
Serum macrophage migration-inhibitory factor as a diagnostic and prognostic
biomarker for gastric cancer.
Cancer. 2009 Dec 1; 115(23):5441-9. Epub 2009 Aug 14.
Impact Factor: 5.238 Contribution: corresponding
author

310. Dai Y, Qiao L, Chan KW, Yang M, Ye J, Zhang R, Ma J, Zou B, Lam CS, Wang
J, Pang R, Tan VP, Lan HY, Wong BC.
Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein
inhibits colon cancer.
Mol Cancer Ther. 2009 Sep;8(9):2762-70.
Impact Factor: 4.8 Contribution: senior author

311. Qiao L, Wong BC

Role of Notch Signaling in colorectal cancer
Carcinogenesis 2009 Dec; 30(12): 1979-86. Epub 2009 Sep 30.
Impact Factor: 5.406 Contribution: corresponding author

312. Ng FH, Wong SY, Lam KF, Chu WM, Chance P, Ling YH, Kng C, Yuen WC,
Lau YK, Kwan A, Wong BC.
Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic
ulcers or erosions.
Gastroenterology. 2010; 138(1): 82-8. Epub 2009 Oct 15.
Impact Factor: 12.591 Contribution: senior author

313. Zou B, Qiao L, Wong BC

Current understanding of the role of PPARgamma in gastrointestinal cancer
PPAR Res 2009; 2009:8:816957 epub 2009 Oct 26

314. Hung IF, Chan P, Leung S, Chan FS, Hsu A, But D, Seto WK, Wong SY, Chan CK,
Gu Q, Tong TS, Cheung TK, Chu KM, Wong BC
 109 BCY Wong - 18 August, 2010

Clarithromycin-amoxycillin-containing triple therapy, a valid empricial first line treatment

for Helicobacter pylori eradication in Hong Kong
Helicobacter 2009 Dec; 14(6): 505-11
Impact Factor: 2.470 Contribution: corresponding author

315. Hui SK, Tse MK, Yang Y, Wong BC, Sze KH

Backbone and side chain (1)H, (13)C and (15)N assignments of the ubiquitin-associated
domain of human X-linked inhibitor of apoptosis protein
Biomol NMR Assign. 2009 Nov 15 epub

316. Yee YK, Tan VP, Chan P, Hung IF, Pang R, Wong BC
Epidemiology of colorectal cancer in Asia
J Gastroenterol Hepatol 2009 Dec; 24(12): 1810-6.
Impact Factor: 1.673 Contribution: corresponding
author

317. Yee YK, Gu Q, Hung I, Tan VP, Chan P, Hsu A, Pang R, Lam CS, Wong BC
Trend of colorectal cancer in Hong Kong: 1983-2006.
J Gastroenterol Hepatol 2010 May;25(5):923-7. Epub 2010 Jan 14.
Impact Factor: 1.673 Contribution: corresponding author

318. Tu SP, Sun YW, Cui JT, Zou B, Lin MC, Gu Q, Jiang SH, Kung HF, Korneluk RG,
Wong BC
Tumour suppressor XIAP-associated factor 1 (XAF1) cooperates with tumour necrosis
factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger
tumour regression
Cancer 2010 Mar 1; 116(5): 1252-63. Epub Jan 15
Impact Factor: 5.238 Contribution: corresponding author

319. Zhang R, Zhang YY, Huang XR, Wu Y, Chung AC, Wu EX, Szalai AJ, Wong BC,
Lau CP, Lan HY
C reactive protein promotes cardiac fibrosis and inflammation in angiotensin II induced
hypertensive cardiac disease
Hypertension 2010 Apr; 55(4): 953-60. Epub Feb 15
Impact Factor: 7.368 Contribution: minor

320. Lam PK, Ng ML, Cheung TK, Wong BY, Tan VP, Fong DY, Wei WI, Wong BC
Rabeprazole is effective in treating laryngopharyngeal reflux
Clin Gastroenterol, Hepatol 2010 Mar 17 epub.
Impact Factor: 6.068 Contribution: corresponding author

321. Tan VP, Chan P, Hung IF, Pang R, Wong BC.

Chemoprophylaxis in colorectal cancer: current concepts and a practical algorithm for
use.
Expert Opin Investig Drugs. 2010 Apr; 19 Suppl 1:S57-66.
Impact Factor: 4.058 Contribution: corresponding author
 110 BCY Wong - 18 August, 2010

322. Zhang W, Jiang B, Guo Z, Sardet C, Zou B, Lam CS, Li J, He M, Lan HY, Pang
R, Hung IF, Tan VP, Wang J, Wong BC.
Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-
mesenchymal transition in colon cancer
Carcinogenesis 2010 Jul; 31(7): 1220-9. Epub 2010 May 11.

323. An X, Ng SS, Xie D, Zeng YX, Sze J, Wang J, Chen YC, Chow BK, Lu G, Poon
WS, Kung HF, Wong BC, Lin MC.
Functional characterisation of cell cycle related kinase (CCRK) in colorectal
cancer carcinogenesis.
Eur J Cancer 2010 Jun; 46(9): 1752-61.

324. Tulassay Z, Stolte M, Engstrand L, Butruk E, Malfertheiner P, Dite P, Tchernev

K, Wong BC, Gottlow M, Eklund S, Wrangstadh M, Herszenyi L, Nagy P.
Twelve-month endoscopic and histological analysis following proton pump
inhibitor based triple therapy in Helicobacter pylori positive patients with gastric
ulcers.
Scand J Gastroenterology 2010 Sep;45(9):1048-58 May 28 epub.

325. Tan VP, Wong BC

Short segment hiatal hernia- the long and the short of it.
J Neurogastroenterology and Motility 2010 Jan 16(1): 1-2.

326. Pang R, Law WL, Chu AC, Poon JT, Lam CS, Chow AK, Ng L, Cheung LW,
Lan XR, Lan HY, Tan VP, Yau TC, Poon RT, Wong BC.
A subpopulation of CD26+ cancer stem cells with metastatic capacity in human
colorectal cancer
Cell Stem Cell 2010 Jun 4; 6(6): 603-15.

327. Ma J, Wang JD, Zhang W, Zou B, Chen WJ, Lam CS, Chen MH, Pang R, Tan
VP, Hung IF, Lan HY, Wang QY, Wong BC.
Promoter hypermethylation and histone hypoacetylation contribute to PDX-1
silencing in gastric cancer
Carcinogenesis 2010 Jul 9 epub

328. Tan VP, Wong BC

Patients vote with their feet for on demand rabeprazole in the maintenance
treatment phase of reflux esophagitis
Aliment Pharmacol Ther 2010 Jul 32(2): 305-7.

329. Tan VP, Wong BC

One size does not fit all – time to regionalize Helicobacter pylori eradication
Aliment Pharmacol Ther 2010 Aug 32(3): 506-7.

330. Tan VP, Yan BP, Hunt RH, Wong BC

Proton pump inhibitor and clopidogrel interaction: the case for watchful waiting
J Gastroenterol Hepatol 2010 Aug; 25(8): 1342-7.
111 BCY Wong - 18 August, 2010
 112 BCY Wong - 18 August, 2010

B) FULL ARTICLES IN LOCAL OR REGIONAL JOURNALS

1. Kumana CR, Kou M, Wong BCY, Lee PW, Li KY.

Drug Audit in Hong Kong with Special Reference to Antibiotics.
Journal of the Hong Kong Medical Association 1993;45(3):177-180

2. Wong BCY.
Pathology forum: a teacher with weight loss and fever. The Hong Kong Practitioner 1998;20(8):
456-57.

3. Wong BCY, Kwok E, Lam SK.

Diagnosis of Helicobacter pylori infection. Journal of Hong Kong Medical Technology
Association 1997/98; 7: 1-7

4. Wong BCY, Ching CK, Lam SK.

Helicobacter pylori infection and gastric cancer. Hong Kong Medical Journal 1999;5:175-9.
Citation: 1

5. Ching CK, Wong BCY.

Who should be treated for Helicobacter pylori infection. Hong Kong Medical Journal. 1999; 5:
151-7.

6. Wong BCY.
Helicobacter pylori and gastric cancer. Hong Kong Society of Gastroenterology Newsletter 1999;
1(1) : 3-4.

7. Wong BCY, Lam SK.

Dyspepsia. Hong Kong Practitioner 2000; 22: 417-425.

8. Wong BCY
Latest development in the management of acid-related diseases. HKMA CME Bulletin 2001;
12: 22-23.

9. He XX, Wong BCY, Lam SK, Xia HHX.

Diagnosis of Helicobacter pylori infection (in Chinese).
World Chinese Journal of Digestology 2002 (in press)

10. Hu WHC, Wong NYH, Lai KC, Hui WM, Lam KF, Wong BCY, Xia HHX, Chan CK,
Chan AOO, Wong WM, Tsang KWT, Lam SK.
Normal 24 hour ambulatory proximal and distal gastro-oesophageal reflux parameters in
Chinese.
Hong Kong Medical Journal. 2002; 8: 168-71.

11. Chan AOO, Wong BCY.

Screening for colorectal cancer.
The Hong Kong Medical Diary 2003; 8(1): 3-5.
 113 BCY Wong - 18 August, 2010

12. Wong WM, Wong BCY

Constipation- an update
The Hong Kong Medical Diary 2004; 9(6):3-6.
 114 BCY Wong - 18 August, 2010

C) FULL ARTICLES SUBMITTED TO INTERNATIONAL JOURNALS

1. Lai KC, Zhou XM, Xia HHX, Zhang HB, Huang XR, Leung SY, Yuen ST, Fan DM,
Hui WM, Wong WM, Lam SK, Wong BCY.
Effect of low-dose aspirin on apoptosis and proliferation of gastric epithelial cells in
patients with or without Helicobacter pylori infection.
Aliment Pharmacol Ther– under revision

2. Chan AOO, Hui WM, Leung G, Hu WH, Lam SK, Wong BCY
Efficacy of Tegaserod for functional constipation in Chinese subjects: a randomised double
blind controlled trial in a single center

3. Wang JD, Gu Q, Yang Y, He H, Lin MC, Li M, Xia HH, Jiang B, Lam SK, Wong WM,
Chan AO, Kung HF, Wong BCY.
Downregulation of XIAP-associated factor 1 (XAF1) through heat shock factor-1 binding in
the promoter region

4. Wong BCY, Chan AOO, Feng RE, Chen J, Cui QC, Wong WM, Yuen MF, Jiang XH,
Lam SK, Soh JW, Weinstein IB.
Altered expression of specific isoforms of protein kinase c in human gastric cancer

5. Tu SP, Lam SK, Jiang XH, Cui JT, Lin MCM, Yang Y, Zou B, Lum CT, Yuen ST, Leung
SY, Jiang SH, Kung HF, Wong BCY.
Inhibition of survivin induces apoptosis and mitotic catastrophe in colon cancer

6. Wong BCY, Wong WM, Ching CK, Hu WHC, Lai KC, Yuen ST, Ho J, Lam SK.
Triple therapy versus long term maintenance anti-secretory treatment in the treatment and
prevention of recurrence of gastric ulcer: a prospective long-term follow-up study

7. Zhang MJ, Wong BCY, Zhou ZF, He LH, Guo YH, Zhou JC, Berg DE, Lam SK, Zhang
JZ.
Dissemination of IS605, IS606 among clinical isolates of Helicobacter pylori in China.

8. Tu SP, Liston P, Cui JT, Lin MCM, Lam SK, Jiang XH, Yang Y, Jiang SH, Lum CT, Yuen
ST, Kung HF, Korneluk RG, Wong BCY
Restoration of XAF1 expression induces apoptosis and inhibits gastric and colon tumor
growth

9. Tu SP, Jiang XH, Lin MCM, Cui JT, Yang Y, Zou B, Zhu YB, Jiang SH, Wong WM, Lam
SK, Kung HF, Wong BCY.
Targeting survivin induces apoptosis and mitotic catastrophe in gastric cancer
 115 BCY Wong - 18 August, 2010

ABSTRACTS & CONFERENCE PAPERS:

1) Wong BCY, Wu PC, Lai CL, Chung HT, Lin HJ, Lau JYN.
Histologic changes induced by interferon-a (IFN-a) compared with doxorubicin
in causing regression in inoperable hepatocellular carcinoma.
Hepatology 1992;16:(4) II:179A
American Association for the Study of Liver Diseases Annual meeting , 1992

2) Lai CL, Yeoh EK, Wong BCY, Lim WL, Chang WK.
Five Year Follow-up of a Randomised Trial of Hepatitis B recombinant DNA
Yeast Vaccine vs. Plasma-derived Vaccine In Children.
Hepatology 1992;16:560
The International Association for the Study of Liver, United Kingdom, 1992.

3) Ip Mary, Wong CY, Chan J, Lam WK.

Inhaled Salmeterol and Sustained-release Theophylline - A Crossover Comparison
in Nocturnal Asthma.
Proceedings of Third Congress of the Asian Pacific Society of Respirology,
October, 1993, Singapore.

4) Chan JCK, Lam WK, Chau PY, Wong BCY, Ip MSM.

Efficacy and safety of once-a-day oral ofloxacin 400mg in treating community-acquired
lower respiratory infection in the moderately compromised patients.
Proceedings of the 12th Asian Pacific Congress on Diseases of the Chest,
Soeul, Korea, 1992

5) Wong BCY, Ching CK, Lam SK, Hu WHC, Lai KC, Tam FSF.
Sero-epidemiology of Helicobacter pylori infection in Hong Kong.
Poster Presentation
10th World Congress of Gastroenterology, 1994;abstracts II:746P

6) Lai KC, Ching CK, Wong CY, Ng M, Chung HT, Hu W, Chan CK, Lam SK.
A study of the efficacy of sucralfate in the prevention of rebleeding after endoscopic
therapy of bleeding peptic ulcer.
Poster Presentation
World Congress of Gastroenterology, Oct 1994
Gastroenterology 1994;106(4): Suppl S A116

7) Lai KC, Hui WM, Wong CY, Ching CK, Ng M, Chung HT, Hu W, Lam SK.
A randomised controlled study of the efficacy of polidocanol in the prevention of
rebleeding from peptic ulcer with nonbleeding visible vessel.
Gastroenterology 1994;106(4): Suppl S A116

8) Lai CL, Ching CK, Tung A, Wong BCY, Lim SP, Dent J, Wu PC.
Short term Lamivudine (LAI) suppresses HBV DNA in chinese HBsAg carriers.
Poster Presentation
Hepatology 1994;20(4):II: A298
 116 BCY Wong - 18 August, 2010

Americal Association for the Study of Liver Diseases Annual Meeting, November, 1994.
Citation: 3

9) Wong BCY, Lai CL, Lo JYC, Lai JY, Kwan WK, Chiu W, Lim WL, Lai ST.
Incidence of acute hepatitis A to E in Hong Kong: a prospective study.
Hepatology 1994; 20(4):II:A414
American Association for the Study of Liver Diseases Annual Meeting,
November, 1994.

10) Ching CK, Lam SK, Hu HC, Wong CY, Ong L, Yuen WK, Gao Z, Chen JS,
Chen BW, Jiang XW, Hou XH, Lu JY, Wang WH.
Survey of gastric cancer in Changle of Fujian- a preliminary report.
Oral Presentation
Proceedings of Hong Kong International Cancer Congress, November, 1994.

11) Wong BCY, Ching CK, Lam SK, Hu WHC, Ong Y, Gao Z, Chen JS, Chen BW,
Jiang XW, Hou XH, Lu JY, Wang QH.
The differential Helicobacter pylori (Hp) infection rates in two contrasting
gastric cancer risk regions of south China.
Poster presentation, Digestive Disease Week, USA 1995
Gastroenterology 1995;108:A553

12) Wong BCY, Ching CK, Lam SK, Lai KC, Hu WHC, Ong LY, Lai CL, Chan CK.
Association of Helicobacter pylori (Hp) infection with hypoalbuminemia and
dietary habits.
Poster presentation, Digestive Disease Week, USA 1995
Gastroenterology 1995;108:A260
Citation: 2

13) Ching CK, Wong BCY, Lam SK, Ong LY, Lai KC, Hu WHC, Lai CL, Lau G,
Covacci A.
Prevalence of cytotoxin-producing Helicobacter pylori (Hp) strains detected
by the anti-CagA assay (ACAA) among patients with peptic ulcer disease and
controls.
Poster presentation
Gastroenterology 1995;108:A70

14) Ching CK. Wong BCY, Lam SK, Ong LY, Covacci A.
Non-ulcer dyspepsia and cytotoxin-producing Helicobacter pylori (Hp)
strains - are they related?
Poster presentation
Gastroenterology 1995;108: A70
Citation: 4

15) Ching CK, Lam SK, Wong CY, Hu WHC, Ong LY, Gao Z, Chen JS, Chen BW,
Jiang XW, Hou XH, Lu JY, Wang WH.
Mass endoscopic screening for gastric cancer and initiation of Helicobacter pylori
 117 BCY Wong - 18 August, 2010

(Hp) eradication therapy in Changle of China-a preliminary report.

Gastroenterology 1995;108: A456.

16) Ching CK, Lam SK, Yung RWH, Leung KP, Wong BCY, Lai KC, Ong LY, Lai CL,
Lau G.
Prevalence of metronidazole resistant Helicobacter pylori (Hp) strains
among the Chinese peptic ulcer disease patients and normals in Hong Kong.
Poster presentation
Gastroenterology 1995;108: A71

17) Wong BCY, Ching CK, Lam SK.

Helicobacter pylori (Hp) does not enhance NSAID-induced gastroduodenal mucosal
damage in the elderly.
Poster presentation
International AGA/Singapore Gastroenterological Meeting, Singapore, September 1995.
Journal of Gastroenterology and Hepatology 1995;10(supp 3): A82

18) Wong BCY, Liang R, Lam SK.

Helicobacter pylori infection and gastric non-Hodgkin’s lymphoma - are they related?
Oral presentation
Third International Conference of Gastroenterology, Hong Kong/Shanghai, 1995
Journal of Gastroenterology and Hepatology 1995;10(supp 4):A131

19) Wong BCY, Ching CK, Lam SK.

High prevalence of Cag-A bearing Helicobacter pylori (Hp) strains detected by the anti-Cag
A assay (ACAA) in patients with gastric adenocarcinoma in Hong Kong.
Oral presentation
Third International Conference of Gastroenterology, Hong Kong/Shanghai, 1995
Journal of Gastroenterology and Hepatology 1995;10(supp 4):A132

20) Michell N, Wong BCY, Eggo M, Langman MJS.

Programmed cell death: How indomethacin treatment reduces colon cancer incidence.
Oral presentation, Midland Gastroenterological Society Meeting, U.K. November,1995.

21) Wong BCY, Michell NM, Langman MJS and Eggo M.

Induction of apoptosis by protein kinase C-1 activator in Colo-205 human colonic
carcinoma cells and its prevention by insulin-like growth factor I.
Poster presentation, Digestive Disease Week, San Francisco, USA, May 1996.
Gastroenterology 1996; 110(4):A615

22) Wong BCY, Michell NM, Jankowski JA, Sanders DSA, Langman MJS, Eggo MC.
Phorbol ester-induced intercellular adhesion of human colonic carcinoma cells is
mediated by E-cadherin.
Poster presentation, Digestive Disease Week, San Francisco, USA, May 1996.
Gastroenterology 1996;110(4): Suppl. S, A615
Citation: 2
 118 BCY Wong - 18 August, 2010

23) Wong BCY, Michell NM, Langman MJS and Eggo M.

Insulin-like Growth Factor I protects human colonic cancer cells from indomethacin-
induced apoptosis.
Gastroenterology 1996 ;110(4):A615

24) Lam SK, Ching CK, Lai KC, Wong BCY, Lai CL, Chan CK, Ong L.
Does treatment of Helicobacter pylori with antibiotics alone heal duodenal ulcer? A
randomised double-blind placebo-controlled study.
Oral presentation, Digestive Disease Week, San Francisco, USA, May 1996.
Gastroenterology 1996;110:(4):A169
Citation: 9

25) Wong BCY, Michell NM, Langman MJS and Eggo M.

Effect of growth factors on proliferation and NSAID-induced apoptosis of human
colonic cancer cells.
Poster presentation,
Proceedings, 10th Asian-Pacific Congress of Gastroenterology, Japan, 1996:484.

26) SZ Ding, CH Cho, SK Lam, ST Yuen, J Ho, WM Hui, GH Zhu, XL Yang, BCY Wong, HL
So.
Involvement of tumour necrosis factor alpha in indomethacin induced gastric mucosal
injury in rats.
International Meeting on Gastroenterology, Endocrinology and Reproduction, Faculty of
Medicine HKU, December 9-10, 1996.

27) BCY Wong, SK Lam, CK Ching, WHC Hu, KC Lai, LY Ong, E Kwok, Z Gao, JS Chen,
BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, A Covacci.
Effect Of Cag-A bearing strains in the eradication of Helicobacter pylori in a high
prevalence area.
Gastroenterology 1997:112(4):A332.

28) BCY Wong, SK Lam, KC Lai, WHC Hu, CK Chan, CK Ching.

Triple therapy vs omeprazole maintenance for prevention of duodenal ulcer relapse.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A333.

29) BCY Wong, SK Lam, CK Ching, WHC Hu, KC Lai, E Kwok, LY Ong, Z Gao, JS Chen,
BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, A Covacci.
Higher prevalence of cytotoxin-producing Helicobacter pylori (hp) strains in an area
with higher prevalence of gastric cancer in south China.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A682.

30) BCY Wong, SK Lam, J Ho, ST Yuen, WHC Hu, CK Ching, E Kwok, LY Ong, Z Gao, JS
Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, A Covacci
Prevalence of cytotoxin-producing Helicobacter pylori (hp) strains in different stages of
the carcinogenesis model in a population with high risk for gastric cancer.
 119 BCY Wong - 18 August, 2010

Poster presentation, Digestive Disease Week, USA 1997

Gastroenterology 1997:112(4):A683.

31) BCY Wong, J Ho, ST Yuen, SK Lam, CK Ching, WHC Hu, KC Lai, LY Ong, Z Gao, JS
Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui.
Intestinal metaplasia and gastric metaplasia in Helicobacter pylori (hp) gastritis in a
population with high risk for gastric cancer
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A682.

32) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, WHC Hu, KC Lai, LY Ong, Z Gao, JS
Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang.
Helicobacter pylori (hp) alone cannot account for development of intestinal metaplasia
in a high gastric cancer risk region in China.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A682.

33) BCY Wong, GH Zhu, ST Yuen, EYT Chan, XL Yang, SZ Ding, SK Lam.
Induction of apoptosis by pharmacological inhibitors of protein kinase C in human
gastric carcinoma cells.
Gastroenterology 1997:112(4):A682.

34) BCY Wong, GH Zhu, MC Eggo, ST Yuen, EYT Chan, SK Lam

Protein kinase C downregulation rescues indomethacin induced apoptosis in human
gastric carcinoma cells.
Gastroenterology 1997:112(4):A683.

35) BCY Wong, GH Zhu, MC Eggo, ST Yuen, EYT Chan, SK Lam

Nonsteroidal antiinflammatory drugs (NSAID) induces apoptosis in human gastric
carcinoma cells.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A683.
Citation: 1

36) KWT Tsang, SK Lam, BCY Wong, WHC Hu, J Karlberg, WK Lam.
High sero-prevalence of Helicobacter pylori in bronchiectasis.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A315.

37) ST Yuen, IKL Chan, WHC Hu, BCY Wong, KC Lai, CK Ching, Z Gao, JS Chen, BW
Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, J Ho, SK Lam.
Population in areas with high gastric cancer incidence has a higher epithelial cell
proliferation rate in the gastric mucosa compared with those in areas with low gastric cancer
incidence.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A688
 120 BCY Wong - 18 August, 2010

38) ST Yuen, IKL Chan, WHC Hu, BCY Wong, KC Lai, CK Ching, Z Gao, JS Chen, BW
Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, J Ho, SK Lam.
Gastric mucosa in patients having gastric ulcer and gastritis exhibits a difference
epithelial cell kinetics compared to those with duodenal ulcer.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A688.

39) KC Lai, BCY Wong, ST Yuen, J Ho, WHC Hu, CK Ching, LY Ong, Z Gao, JS Chen, BW
Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui, K Miki, A Covacci, SK Lam.
Pepsinogen levels in subjects with cag-A-bearing Helicobacter pylori strains from an area
with high gastric cancer rate.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A599

40) KC Lai, CK Ching, BCY Wong, WHC Hu, LY Ong, Z Gao, JS Chen, BW Chen, XW Jiang,
XH Hou, JY Lu, QH Wang, WM Hui, K Miki, SK Lam.
Serum pepsinogen levels in different gastroduodenal lesions and in subjects from two
areas with contrasting gastric cancer rates.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A599

41) KC Lai, WM Wong, WM Hui, BCY Wong, WHC Hu, SK Lam.

Eradication of Helicobacter pylori in patients with duodenal ulcer hemorrhage- 5 years
follow-up.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A190

42) KC Lai, H Su, BCY Wong, WM Hui, E Kwok, A Covacci, SK Lam.

Prevalence of Helicobacter pylori infection and cagA-bearing Helicobacter pylori strains in
Chinese patients on continuous non steroidal anti-inflammatory drugs.
Gastroenterology 1997:112(4):A190

43) KC Lai, WM Hui, WHC Hu, BCY Wong, E Kwok, SK Lam.

Serology is not useful in the follow up and confirmation of Helicobacter pylori
eradication.
Gastroenterology 1997:112(4):A191.

44) KC Lai, KM Chu, WM Hui, BCY Wong, SK Lam.

Non-invasive tests before endoscopy in area with high prevalence of gastric carcinoma -
Helicobacter pylori serology or urea breath test?
Oral presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A599
Citation: 1

45) JS Chen, BCY Wong, YN Wu, H Lin, JL Wang, J Ho, ST Yuen, CK Ching, WHC Hu, KC
Lai, LY Ong, Z Gao, JS Chen, BW Chen, XH Hou, JY Lu, XW Jiang, QH Wang, WM Hui,
SK Lam.
 121 BCY Wong - 18 August, 2010

Preliminary analysis of dietary risk factors for precancerous gastric lesions in population of
Changle, a high risk area of gastric cancer in China.
Oral presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A547.
Citation: 4

46) WHC Hu, SK Lam, J Ho, CK Ching, KC Lai, LY Ong, BCY Wong , ST Yuen, Z Gao, KY
Chau, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang, WM Hui.
Increased prevalence of premalignant histological changes in the population of an area with
high gastric cancer incidence in China.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A581.

47) WM Wong, KC Lai, WM Hui, BCY Wong, WHC Hu, E Kwok, CL Lai, SK Lam.
Gastrin hypersensitivity, maximal acid output and gastrin release in relation to Helicobacter
pylori serology and cytotoxin-associated antigen antibody in duodenal ulcer patients.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A333.

48) GH Zhu, XL Yang, KC Lai, BCY Wong, ST Yuen, J Ho, SK Lam.

No synergistic effect in the induction of apoptosis I gastric epithelial cells by Helicobacter
pylori and non-steroidal anti-inflammatory drugs.
Gastroenterology 1997; 112(4): A342.

49) SZ Ding, CH Cho, ST Yuen, GH Zhu, XL Yang, BCY Wong, J Ho, WM Hui, SK Lam.
Involvement of mucosal TNF- in the indomethacin-induced rat gastric mucosal injury.
Gastroenterology;1997;112(4): A103.

50) SZ Ding, ST Yuen, GH Zhu, BCY Wong, HL So, J Ho, WM Hui, CH Cho, SK Lam.
Neutrophil margination and myeloperoxidase activity in the indomethacin-induced gastric
mucosal injury in rats.
Gastroenterology 1997;112(4): A103.

51) AE Lewis, BCY Wong, MJS Langman, MC Eggo.

Role of protein kinase C isoenzymes in IGF-I-mediated cell growth in the human colon
carcinoma Colo 205 cell line.
Poster presentation, Digestive Disease Week, USA 1997
Gastroenterology 1997:112(4):A603.

52) BCY Wong, NP Michell, AE Lewis, D Watters, MJS Langman, MC Eggo.

IGF-I rescues colonic cells from apoptosis induced by protein kinase C activators and
indomethacin.
Proceedings, 79th Annual Meeting of the Endocrine Society, USA, 1997, P1195.

53) AE Lewis, BCY Wong, MJS Langman, MC Eggo.

Protein kinase C isoenzymes in IGF-I-mediated cell proliferation.
Poster presentation, British Endocrine Society Meeting 1997
 122 BCY Wong - 18 August, 2010

J Endocrinology 1997; 152: P142

54) BCY Wong, GH Zhu, ST Yuen, EYT Chan, KC Lai, SK Lam.

Differential effect of pharmacological inhibitors of protein kinase C in growth inhibition
and apoptosis of human gastric cancer cells.
Poster presentation, American Association of Cancer Research Annual meeting, 1997
Proceedings, American Association of Cancer Research annual meeting, USA,
1997:38:92.

55) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, WHC Hu, KC Lai, LY Ong, Z Gao, JS
Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang.
High prevalence of intestinal metaplasia in a high gastric cancer risk region in China.
Poster presentation, 6th United European Gastroenterology Week, UK, Oct, 1997.
Gut 1997;41(Suppl 3): A171

56) BCY Wong, SK Lam, KC Lai, WHC Hu, CK Ching, WM Hui.

Helicobacter pylori - our local experience
Proceedings, 110th Anniversary Scientific Congress, Faculty of Medicine, University of
Hong Kong, Oct 1997.

57) BCY Wong, SK Lam

Epidemiology, diet,Helicobacter pylori infection and Gastric Cancer
J Gastroenterol Hepatol 1997;12:Suppl: A158.

58) GH Zhu, BCY Wong, CK Ching, ST Yuen, EYT Chan, KC Lai, SK Lam.
Wild-type p53-dependent upregulation of c-myc mRNA is associated with indomethacin
induced apoptosis in gastric cancer cells.
J Gastroenterol Hepatol 1997;12:Suppl: A182

59) WM Wong, BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, WHC Hu, KC Lai, LY
Ong, Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, QH Wang.
Helicobacter pylori (hp) alone cannot account for development of gastric atrophy in a
high gastric cancer risk region in China.
J Gastroenterol Hepatol 1997;12:Suppl: A188

60) KC Lai, SK Lam, BCY Wong, WM Hui, WHC Hu.

A simplified but equally accurate C13 urea breath test for Helicobacter pylori.
The Hong Kong Practitioner 1998;20: 2(suppl): 20

61) KC Lai, WM Hui, SK Lam, BCY Wong, KM Chu, WM Wong, WHC Hu.
Maintenance H2- antagonist is not necessary after eradication of Helicobacter pylori in
bleeding peptic ulcers
The Hong Kong Practitioner 1998;20: 2(suppl): 21

62) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, E Kwok, WHC Hu, KC Lai, LY Ong,
Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, WH Wang, K Miki, A Covacci.
 123 BCY Wong - 18 August, 2010

Age is a predicting factor for the association between CagA positive Helicobacter pylori
infection and serum pepsinogen I:II ratio in a high gastric cancer risk region in China.
The Hong Kong Practitioner 1998;20: 2(suppl): 75

63) GH Zhu, BCY Wong, CK Ching, ST Yuen, EYT Chan, KC Lai, SK Lam.
Wild-type p53-dependent upregulation of c-myc mRNA is associated with indomethacin
induced apoptosis in gastric cancer cells
The Hong Kong Practitioner 1998;20: 2(suppl): 76

64) BCY Wong, GH Zhu, ST Yuen, EYT Chan, KC Lai, SK Lam.

Induction of apoptosis by pharmacological inhibitors of protein kinase C in gastric
cancer cell line is mediated by p53, c-myc and bcl-2 related proteins.
Poster presentation, American Association of Cancer Research Annual meeting, 1998
Proceedings, American Association of Cancer Research annual meeting, USA,1998: 39:
601.

65) GH Zhu, BCY Wong, MC Eggo, CK Ching, ST Yuen, EYT Chan, KC Lai, SK Lam.
Indomethacin induced apoptosis in human gastric cancer cells is mediated by protein
kinase C/ c-myc pathway.
Poster presentation, American Association of Cancer Research Annual meeting, 1998
Proceedings, American Association of Cancer Research annual meeting, USA,1998: 39:
137

66) KC Lai, SK Lam, WM Hui, BCY Wong, CS Lau, WHC Hu, ZF Wen.
Can eradication of Helicobacter pylori prevent future development of peptic ulcers in
patients receiving long-term continuous nonsteroidal anti-inflammatory drugs.
Gastroenterology 1998: 114(4)(part 2):A192. G0787
Citation: 11

67) GH Zhu, XL Yang, KC Lai, CK Ching, BCY Wong, WM Hui, ST Yuen, J Ho, SK Lam.
Nonsteroidal anti-inflammatory drugs could reverse Helicobacter pylori-induced
imbalance between proliferation and apoptosis in gastric epithelial cells.
Gastroenterology 1998: 114(4)(part 2):A346. G1411

68) GH Zhu, BCY Wong, CK Ching, ST Yuen, EYT Chan, KC Lai, SK Lam.
Wild-type p53-dependent upregulation of c-myc is associated with differential apoptotic
response in indomethacin-treated human gastric cancer cells.
Gastroenterology 1998: 114(4)(part 2):A346. G1412

69) GH Zhu, BCY Wong, CK Ching, KC Lai, SK Lam.

Downregulation of protein kinase C inhibits indomethacin-induced apoptosis in gastric
epithelial cells by differential regulation of apoptosis-related genes. Gastroenterology
1998: 114(4)(part 2):A709. G2935

70) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, E Kowk, WHC Hu, KC Lai, LY Ong,
Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, WH Wang, K Miki, A Covacci.
 124 BCY Wong - 18 August, 2010

Age is a predicting factor for the association between CagA positive Helicobacter pylori
infection and serum pepsinogen I:II ratio in a high gastric cancer risk region in China.
Gastroenterology 1998: 114(4)(part 2):A333. G1359

71) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, E Kowk, WHC Hu, KC Lai, LY Ong,
Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, WH Wang, A Covacci.
Role of CagA status in atrophic gastritis and intestinal metaplasia in a high gastric
cancer risk region in China.
Gastroenterology 1998: 114(4)(part 2):A333. G1360

72) SZ Ding, CH Cho, BCY Wong, KC Lai, GKK Lau, WM Hui, SK Lam.
TNF- and IL-1 induce interleukin-8 response in human gastric epithelial cells and the
signal pathway is mediated by protein tyrosine kinase and dexamethasone-sensitive
mechanism.
Gastroenterology 1998: 114(4)(part 2):A585. G2397

73) BCY Wong, KM Chu, SK Lam, E Kwok, KC Lai, WHC Hu, CK Ching, A Covacci.
CagA-positive strains increase the risk of gastric cancer in Hong Kong with moderate
prevalence of Helicobacter pylori infection and gastric cancer mortality.
Gastroenterology 1998: 114(4)(part 2):A705. G2914
Citation: 1

74) BCY Wong, SK Lam, WM Wong, , J Ho, ST Yuen, CK Ching, E Kowk, WHC Hu, KC
Lai, LY Ong, Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, WH Wang.
Helicobacter pylori alone cannot account for development of atrophic gastritis and
intestinal metaplasia in a high gastric cancer risk region in China.
Gastroenterology 1998: 114(4)(part 2):A705 G2915

75) KC Lai, WM Hui, SK Lam, BCY Wong, KM Chu, WM Wong, WHC Hu.
Maintenance of H2-antagonist is not necessary after eradication of Helicobacter pylori in
bleeding peptic ulcers.
Gastroenterology 1998: 114(4)(part 2):A192. G0790

76) KC Lai, SK Lam, BCY Wong, WM Hui, WHC Hu.

A simplified but equally accurate C-13 urea breath test for Helicobacter pylori.
Gastroenterology 1998: 114(4)(part 2):A191. G0786

77) KC Lai, SK Lam, WM Hui, BCY Wong, CS Lau, WHC Hu, ZF Wen.
Eradication of Helicobacter pylori did not accelerate the healing of gastric and duodenal
ulcers /erosions in patients on long-term continuous nonsteroidal anti-inflammatory
drugs.
Gastroenterology 1998: 114(4)(part 2):A192 G0788

78) AE Lewis, MJS Langman, BCY Wong, D Watters, MC Eggo.

Protein kinase C  downregulation mediates apoptosis in the adenocarcinoma cell line
colo 205.
Gastroenterology 1998: 114(4)(part 2):A635. G2617
 125 BCY Wong - 18 August, 2010

79) KW Wong, BCY Wong, CK Chan, WM Wong, MF Yuen, KC Lai, WHC Hu, MAN
Chong, SK Lam.
Open Access Upper Endoscopy in Hong Kong
Proceedings, Hospital Authority Convention, Hong Kong. 1998

80) BCY Wong, SK Lam, CK Ching, J Ho, ST Yuen, E Kowk, WHC Hu, KC Lai, LY Ong,
Z Gao, JS Chen, BW Chen, XW Jiang, XH Hou, JY Lu, WH Wang, A Covacci.
CagA does not increase the prevalence of atrophic gastritis and intestinal metaplasia in a
high gastric cancer risk region in China.
J Gastroenterol Hepatol 1998:13 ; Suppl A94.

81) Lai KC, Lam SK, Hui WM, Wong BCY, Lau CS.
Helicobacter pylori eradication cannot prevent peptic ulcers development in stable
patients on long-term NSAIDs.
Digestion 1998; 59:Suppl 3: 214.

82) Chan AOO, Wong BCY, Chu KM, Lam SK, Kwok E, Lai KC, Hu WHC, Ching CK,
Covacci A.
CagA status and not Hp status predicts the risk of gastric cancer in population with
moderate prevalence of H. pylori infection.
Digestion 1998; 59:Suppl 3: 440.

83) Wong BCY, Lam SK, Ching CK, Ho J, Yuen ST, Kwok E, Hu W, Lai KC, Ong LY,
Gao
Z, Chen JS, Chen BW, Jiang XW, Hou XH, Lu JY, Wang WH, Miki K, Covacci A.
Association between CagA positive Helicobacter pylori infection and serum pepsinogen
I:II ratio in a high risk region in China.
Digestion 1998; 59:Suppl 3: 458.

84) Lai KC, Lam SK, Wong BCY, Hui WM, Hu WHC.
Both fasting and test meal can be omitted in the C13 urea breath test for Helicobacter
pylori.
Digestion 1998; 59:Suppl 3: 466.

85) Lewis AE, Wong BCY, Jankowski JA, Langman MJS, Eggo MC.
Importance of E-cadherin-mediated cell adhesion in prevention of apoptosis
Digestion 1998; 59:Suppl 3: 672.

86) C Cheng CC, Yuen MF, Wong WM, Wong CY, Ngan H, Fan ST, Wu CH, Chan OO,
Lai CL.
Changing pattern of hepatocellular carcinoma (HCC): The effect of cancer
screening for chronic hepatitis B and C carriers.
Hepatology 1998; 28: (4) 2381, Part 2, Suppl.

87) Tsang KWT, Lam WK, Kwok E, Hu H, Wong BCY, Lam SK.
Helicobacter pylori CagA sero-prevalence in Chinese patients with bronchiectasis.
 126 BCY Wong - 18 August, 2010

Amer J Resp and Critical Care Med 1999; 159: 9: A307

88) Lai KC, Chan OO, Hui WM, Wong CY, Hu HC, Chan CK, Lai CL, Lau KK, Lam SK.
A randomised controlled study comparing the efficacy of once-daily triple therapy with
twice-daily triple therapy in the eradication of Helicobacter pylori.
The Hong Kong Practitioner 1999; 21: 2(suppl); 18

89) Wong WM, Wong BCY, Goodlad RA, Mandir M, Lam SK, Wright NA.
Proliferation characteristics and histogenesis of human colonic polyps - a microdissction
study.
The Hong Kong Practitioner 1999; 21: 2(suppl); 18

90) Chan AOO, Chu KM, Kwok E, Lai KC, Hui WM, Wong CY, Lam SK.
Serum soluble E-cadherin concentration in patients with gastric cancer.
The Hong Kong Practitioner 1999; 21: 2(suppl); 53

91) Jiang XH, Yuen ST, Lam SK, Eggo MC, Lai KC, Hu WHC, Leung SY, Wong BCY.
Arsenic trioxide-induced apoptosis in human gastric cancer is mediated by protein kinase C
and p53-dependent pathway.
The Hong Kong Practitioner 1999; 21: 2(suppl); 53

92) Zhu GH, Wong BCY, Slosberg ED, Eggo MC, Ching CK, Yuen ST, Lai KC, Weinstein IB,
Lam SK.
Overexpression of protein kinase C 1 isoenzyme suppresses indomethacin-induced
apoptosis in gastric epithelial cells.
The Hong Kong Practitioner 1999; 21: 2(suppl); 54

93) Zhang HB, Wong BCY, Lam SK, Lai KC, Hu WHC, Fan DM, Leung SY, Yuen ST.
Expression of Ras, Raf-1, MEK-1 and MAPK-1 kinase pathway in human pre-malignant
gastric lesions and gastric carcinomas.
The Hong Kong Practitioner 1999; 21: 2(suppl); 56

94) Tsang KWT, Lam WK, Kwok E, Leung R, Hu W, Wong BCY, Lam SK.
Sero-prevalence of Helicobacter pylori cagA in Chinese patients with bronchiectasis.
E.R.S. annual congress, Madrid October 1999.

95) Zhu GH, Wong BCY, Slosberg ED, Eggo MC, Ching CK, Yuen ST, Lai KC, Weinstein
IB, Lam SK.
Preferential inhibition of protein kinase C-1 isoenzyme mediates indomethacin-induced
apoptosis of gastric epithelial cells.
Proceedings, American Association of Cancer Research annual meeting, USA,1999: 40:
137.

96) Wong WM, Wong BCY, Goodlad RA, Mandir N, Lam SK, Wright NA.
Proliferation characteristics and histogenesis of human colonic polyps- a microdissection
study
Gastroenterology 1999; 116 (4 part 2):A525.G2306
 127 BCY Wong - 18 August, 2010

97) Wong BCY, Lam SK, Chan CK, Wong WM, Yuen MF, Hu WHC, Chong MAN, Lai KC.
Open Access upper endoscopy service in Hong Kong.
Gastroenterology 1999; 116 (4 part 2): A104.G0450

98) Wong BCY, Tang VSY, Lam SK, Lai KC, Hu WHC, Lau G, Lai CL, Chan CK, Chan
OO.
Home-made rapid urease test is as good as commercial kit in testing for Helicobacter
pylori in Hong Kong Chinese
Gastroenterology 1999; 116 (4 part 2): A356. G1558

99) Wong BCY, Lam SK, Lai KC, Hu WHC, Chan CK, Lau G, Lai CL, Ong L, Ching CK.
Triple therapy for Helicobacter pylori eradication is more effective than long-term
maintenance anti-secretary treatment in the prevention of recurrence of gastric ulcer: a
prospective long-term follow-up study.
Gastroenterology 1999; 116 (4 part 2): A.356.G1559

100) Wong BCY, Wong KW, Lam SK, Lai KC, Hu WHC, Lau GKK, Lai CL, Chan CK,
Chan OO, Go R.
A simplified C13-urea breath test for detection of Helicobacter pylori infection.
Gastroenterology 1999; 116 (4 part 2): A356. G1560

101) Wong BCY, Tang VSY, Lam SK, Lai KC, Hu WHC, Lau G, Lai CL, Chan OO, Chan
CK.
Evaluation of whole blood testing for Helicobacter pylori in Chinese.
Gastroenterology 1999; 116 (4 part 2): A357.G1561

102) Lam SK, Wong BCY.

Prospective double-blind randomized placebo-controlled study comparing two
lansoprazole-based triple therapy and one dual therapy for Helicobacter pylori-related
duodenal ulcer: An Asian multicenter study.
Gastroenterology 1999; 116 (4 part 2): A357. G1562

103) Chan AOO, Chu KM, Hui WM, Wong CY, Kwok E, Lai KC, Lam SK.
Serum soluble E-cadherin concentration is a good prognostic marker for patients with
gastric cancer.
Gastroenterology 1999; 116 (4 part 2): A386. G1689

104) Wong BCY, Zhang HB, Lam SK, Lai KC, Hu WHC, Fan DM, Leung SY, Yuen ST.
Expression of Ras, Raf-1, MEK-1 and MAPK-1 Kinase pathway in human pre-
malignant gastric lesions.
Gastroenterology 1999; 116 (4 part 2): A530. G2330

105) Wong BCY, Ching CK, Lam SK, Wong KW, Tam SCF, Lai KC, Chan CK, Hu WHC.
A pilot study of colorectal cancer screening project in Hong Kong.
Gastroenterology 1999; 116 (4 part 2): A530.G2331
 128 BCY Wong - 18 August, 2010

106) Zhu GH, Lam SK, Slosberg ED, Eggo MC, Ching CK, Yuen ST, Lai KC, Weinstein
IB, Wong BCY.
Overexpression of protein kinase C-1 isoenzyme suppresses indomethacin-induced
apoptosis in gastric cancer cells.
Gastroenterology 1999; 116 (4 part 2): A531.G2332

107) Wong BCY, Jiang XH, Yuen ST, Lam SK, Eggo MC, Lai KC, Hu WHC, Leung SY.
Arsenic trioxide-induced apoptosis in human gastric cancer is mediated by protein kinase C
and p53-dependent pathway.
Gastroenterology 1999; 116 (4 part 2): A531.G2333

108) Lai KC, Hui WM, Wong BCY, Lam SK.

Bleeding duodenal ulcers have lower gastric urease activity than uncomplicated
duodenal ulcers.
Gastroenterology 1999; 116 (4 part 2): A227.G0991

109) Lai KC, Chan OO, Hui WM, Wong CY, Chan CK, Lai C, Lau KK, Lam SK.
A randomised controlled study comparing the efficacy of once-daily triple therapy with
twice daily tiple therapy in the eradication of Helicobacter pylori.
Gastroenterology 1999; 116 (4) G0992 part 2 : A228. G0992

110) Wong BCY, Chan JKF, Lam SK, Chan CK, Lai KC, Hu W, Chan O, Go R, Carr-Locke D.
Virtual colonoscopy with 3-dimensional CT scan reconstruction for detection of colonic
lesions in Hong Kong Chinese
Gastrointestinal Endoscopy 1999; 49: (4) 425, Part 2: AB161.
Citation: 1

111) Yuen MF, Ooi C, Wong WM, Chan OO, Wong BCY, Lai CL.
A pilot study of transcatheter arterial interferon-embolization (TAIE) for hepatocellular
carcinoma.
Hepatology 1999; 30: (4) 682A Part 2 Suppl. S

112) Wong BCY, Lam SK.

Cytokines and eicosanoids in apoptosis of GI tumours
J Gastroenterol Hepatol 2000; 15 (Suppl): B10.

113) Lai KC, Lam SK, Wong BCY, Hu WHC, Ching CK, Ong LY, Gao Z, Chen JS, Chen BW,
Jiang XW, Hou XH, Lu JY, Wang QH, Hui WM.
CagA bearing Helicobacter pylori rather than age is the major determinant of low
pepsinogen I/II ratio in a population with high gastric cancer rate.
J Gastroenterol Hepatol 2000; 15 (Suppl): B56.

114) Hu WHC, Lam SK, Ho J, Yuen ST, Ching CK, Wong BCY, Lai KC, Covacci A, Ong LY,
Chen BW, Jiang XW, Hou XH, Lu JY, Wang QH, Hui WM.
CagA positivity is not related to premalignant gastric lesions in Chinese Helicobacter pylori
carriers.
J Gastroenterol Hepatol 2000; 15 (Suppl): B57
 129 BCY Wong - 18 August, 2010

115) Ng FH, Wong SY, Ng WF, Wong BCY.

Prolonged storage of frozen unbuffered rapid urease test.
J Gastroenterol Hepatol 2000; 15 (Suppl): B109.

116) Jiang XH, Yang D, Lam SK, Jiang SH, Yuen ST, Cho CH, Lai KC, Wong BCY.
Tripterygium wilfordii Hook f induced apoptosis in gastric cancer through p-53 dependent
or p-53-independent pathway.
J Gastroenterol Hepatol 2000; 15 (Suppl): B119.

117) Wang WH, Wong BCY, Mukhopadhay AK, Berg DE, Cho CH, Lai KC, Hu WHC, Fung
FMY, Hui WM, Lam SK.
High prevalence of Helicobacter pylori infection with dual resistance to metronidazole and
clarithromyin in Hong Kong.
J Gastroenterol Hepatol 2000; 15 (Suppl): B119.

118) Wong WM, Wong BCY, Wang WH, Fung FMY, Chu KM, Lai KC, Hu WHC, Yuen MF,
Lau GKK, Chan CK, Lai CL, Lam SK.
One-week ranitidine bismuth citrate-based low dose clarithromycin triple therapy is
superior to omeprazole-based regime for the eradication of Helicobacter pylori (H.
Pylori) in Hong Kong with high prevalence of metronidazole resistance
Gastroenterology 2000; 118: 4 (suppl 2): A503

119) Jiang XH, Lam SK, Jiang SH, Yuen ST, Cho CH, Lai KC, Wong BCY.
Involvement of caspase–3 activation and p53 in arsenic trioxide induced apoptosis in
human gastric cancer cells.
Gastroenterology 2000; 118: 4 (suppl 2): A534

120) Jiang XH, Lam SK, Yang D, Jiang SH, Yuen ST, Cho CH, Lai KC, Wong BCY.
Apoptosis induced by triptolide in human gastric cancer is dependent on the constitutive
expression of wild type p53 and activation of caspases
Gastroenterology 2000; 118: 4 (suppl 2): A534

121) Wang WH, Wong BCY, Berg DE, Fung FMY, Lai KC, Wong WM, Wong KW, Cho CH,
Lam SK.
Mixed genotype and metronidazole susceptibility patterns of Helicobacter pylori in
Hong Kong
Gastroenterology 2000; 118: 4 (suppl 2): A503

122) Fan XM, Lam SK, Yuen ST, Cho CH, Wong WM, Lai KC, Leung SY, Wong BCY.
Inhibition of proteasome function induced apoptosis in gastric cancer cells
Gastroenterology 2000; 118: 4 (suppl 2): A532

123) Wong WM, Ng MMT, Chan AOO, Yuen MF , Wong BCY, Lai KC, Lam SK, Lai CL.
Pyogenic liver abscess in the 1990- the medical perspective
Gastroenterology 2000; 118: 4 (suppl 2): A327
 130 BCY Wong - 18 August, 2010

124) Lai KC, Lam SK, Hui WM, Wong CY, Chu KM, Hu W, Wong WM, Chan OO, Lai CL,
Lau KK, Yuen MF, Chan CK.
Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in NSAIDs
users.
Gastroenterology 2000; 118: 4 (1458 Part 1 Suppl 2): A327

125) Lai KC, Lam SK, Hui WM, Wong CY, Hu W, Wong WM, Chan OO, Yuen MF.
Eradication of Helicobacter pylori could not prevent development of gastrointestinal
complications in patients requiring long term low dose aspirin
Gastroenterology 2000;118: 4 (suppl 2): A250.

126) Guo X, Ko JK, Wong BC, Cho CH.

Pathogenic role of cyclooxygenase-2 expression in the initiation of experimental
inflamatory bowel disease induced by trinitrobenzene sulfonic acid in rats.
Gastroenterology 2000; 118: 4 (suppl 2): A345

127) Lewis AE, Wong BC, Watters D, Langman MJ, Eggo MC.
Lysosomal protease inhibitors block PKC-mediated apoptosis in colo 205 cells.
Gastroenterology 2000; 118: 4 (suppl 2): A536

128) Yuen MF, Ooi C, Wong WM, Chan OO, Wong BCY, Lai CL.
A pilot study of transcatheter arterial interferon embolisation for hepatocellular
carcinoma.
Gastroenterology 2000; 118: 4 (88 part 1 suppl 2): A915

129) Tang VSY, Wong BCY, Wong WM, Fung FMY, Lai KC, Hu WHC, Lau GKK, Chan
CK, Lai CL, Lam SK.
Accuracy of invasive and non-invasive diagnostic tests for Helicobacter pylori.
Gastroenterology 2000; 118: 4 (suppl 2): A1313

130) Jiang XH, Lam SK, Jiang SH, Cho CH, Lai KC, Lin MCM, Kung HF, Wong BCY.
Overexpression of protein kinase C-1 isoenzyme suppresses SC-236 induced apoptosis
In gastric epithelial cells.
Proceedings, Second Joint Scientific Meeting, Hong Kong Society of Gastroenterology,
Hong Kong Society of Digestive Endoscopy, Hong Kong Society for Coloproctology, 2,
September, 2000.

131) Fan XM, Lam SK, Zhou XM, Wang WP, Cho CH, Leung SY, Yuen ST, Lin MCM, Kung
HF, Wong BCY.
Specific cyclooxygenase-2 (COX-2) inhibitor induce apoptosis in gastric cancer cells.
Proceedings, Second Joint Scientific Meeting, Hong Kong Society of Gastroenterology,
Hong Kong Society of Digestive Endoscopy, Hong Kong Society for Coloproctology, 2,
September, 2000.

132) Zhou XM, Lai KC, Lam SK, Zhang HB, Huang XR, Fan XM, Hui WM, Fan DM, Wong
BCY.
 131 BCY Wong - 18 August, 2010

Induced gastric mucosal apoptosis in Helicobacter pylori positive patients taking low dose
aspirin : a 6-month case-control study.
Proceedings, Second Joint Scientific Meeting, Hong Kong Society of Gastroenterology,
Hong Kong Society of Digestive Endoscopy, Hong Kong Society for Coloproctology, 2,
September, 2000.

133) Wang WP, Fan XM, Lam SK, Cho CH, Lin MCM, Kung HF, Hui WM, Wong BCY
Inhibition of 12-lipoxygenase induced apoptosis in human gastric cancer cells
Proceedings, Second Joint Scientific Meeting, Hong Kong Society of Gastroenterology,
Hong Kong Society of Digestive Endoscopy, Hong Kong Society for Coloproctology, 2,
September, 2000.

134) Wong BCY, Jiang XH, Zhu GH, Lin MCM, Kung HF, Lam SK.
Chemoprevention of gastric cancer through modulation of Protein Kinase C by non-
steroidal anti-inflammatory drugs.
5th International Symposium on Predictive Oncology and Therapy : Impact of
Biotechnology on Cancer Diagnostic & Prognostic Indicators, October 2000, Geneva,
Switzerland

135) Hui CK, Yuen MF, Ooi C, Wong WM, Chan OO, Wong BCY, Lai CL.
A pilot study of transcatheter arterial interferon embolization for hepatocellular
carcinoma.
Poster presentation. 6th Medical Research Conference, Department of Medicine,
University of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 16

136) Wong WM, Wong BCY, Tang VSY, Lai KC, Hu WHC, Lam SK.
An evaluation of PyloriTek test for the diagnosis of Helicobacter pylori infection in
Chinese – before and after eradication therapy.
Poster presentation. 6th Medical Research Conference, Department of Medicine,
University of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 17

137) Wong BCY, Wang WH, Lau GKK, Wong WM, Fung FMY, Kung NNS, Chu KM, Lai
KC, Hu WHC, Hu FL, Liu XG, Chan CK, Yuen MF, Hui WM, Lam SK.
Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal
ulcers: a randomized controlled study.
Oral presentation. 6th Medical Research Conference, Department of Medicine, University
of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 18

138) Xia HHX, Wong BCY, Wong KW, Wong SY, Wong WM, Lai KC, Hu WHC, Chan CK,
Lam SK.
Non-H. pylori , non-NSAID duodenal ulcers: clinical and endoscopic characteristics
6th Medical Research Conference, Department of Medicine, University of Hong Kong,
13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 18
 132 BCY Wong - 18 August, 2010

139) Wong WM, Wong BCY, Wong KW, Li TM, Cheung KL, Fung FMY, Xia HHX, Lam
SK
Low dose 13C-Urea breath test with citrate is equally reliable for the detection of
Helicobacter pylori infection in Chinese
6th Medical Research Conference, Department of Medicine, University of Hong Kong,
13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 19

140) Hu WHC, Hui WM, Lam CLK, Wong YH, Lai KC, Wong BCY, Yuen MF, Wong WM,
Xia HHX, Lam SK.
Empirical endoscopy, Helicobacter test and treat and empirical prokinetics are equally
effective in symptom resolution in primary care patients presenting with dyspepsia.
Oral presentation. 6th Medical Research Conference, Department of Medicine, University
of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 19

141) Lai KC, Lam SK, Chu KM, Hui WM, Wong BCY, Hu WHC, Wong WM, Yuen MF, Chan
OO, Lai CL, Lau GKK, Chan CK.
H. pylori eradication vs H. pylori eradication combined with proton pump inhibitor in
prevention of aspirin induced peptic ulcer complications.
Oral presentation. 6th Medical Research Conference, Department of Medicine, University
of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 20

142) Huang XR, Hui WC, Chen YX, Wong BCY, Metz C, Bucala R, Fung PCW, Lam SK,
Lan HY.
Macrophage migration inhibitory factor is an important mediator in gastric inflammatory
disease.
Oral presentation. 6th Medical Research Conference, Department of Medicine, University
of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 45

143) Fan XM, Lin MCM, Lam SK, Kung HF, Masferrer JL, Koko AT, Cho CH, Wong BCY.
Specific inhibition of cyclooxygenase-2 down-regulates NF-kappaB activation in gastric
cancer cells by blocking its nuclear translocation
6th Medical Research Conference, Department of Medicine, University of Hong Kong,
13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 45

144) Jiang XH, Lin MCM, Lam SK, Kung HF, Masferrer JL, Slosberg ED, Soh JW,
Weinstein IB, Wong BCY.
Overexpression of protein kinase C-beta 1 isoenzyme suppresses SC-236-induced
apoptosis in gastric epithelial cells.
Oral presentation. 6th Medical Research Conference, Department of Medicine, University
of Hong Kong, 13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 46.
 133 BCY Wong - 18 August, 2010

145) Xia HHX, Zhang GS, Talley NJ, Henwood C, Wyatt JM, Adams S,Wong BCY, Lam SK
Expression of Ki-67 and bcl-2 in gastric epithelial cells : role of antralization in gastric
carcinogenesis.
6th Medical Research Conference, Department of Medicine, University of Hong Kong,
13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 46

146) Hui WC, Fung PCW, Wong BCY, Tipoe GL, Lam SK.
Change in endogenous nitric oxide production in the healing of gastric ulcer induced by
acetic acid.
6th Medical Research Conference, Department of Medicine, University of Hong Kong,
13-14 January, 2001
The Hong Kong Practitioner 2001; 23 (2- suppl): 56

147) Jiang XH, Lam SK, Lin MCM, Cho CH, Lai KC, Kung HF, Yang D, Wong BCY.
P53 status determines nuclear factor-kappa B response in Triptolide-induced apoptosis in
gastric cancer.
Poster presentation, 92nd Annual meeting of the American Association of Cancer Research
Proceedings of American Association of Cancer Research Annual Meeting, 2001,Vol 42:
pg 659.

148) Feng ZH, Guan XY, Ho SL, Sham J, Wong BCY.

The role of phosphorylated CREB in ovary tumor cell lines for the expression of human
Catechol-O-Methyltransferase gene.
Poster presentation, 92nd Annual meeting of the American Association of Cancer Research
Proceedings of American Association of Cancer Research Annual Meeting, 2001,Vol 42:
pg 897.

149) Wong BCY

Diet and gastric cancer
Gastro 2001 Annual Scientific Meeting of Malaysian Society of Gastroenterology
The Medical Journal of Malaysia 2001; 56 (Suppl A): 23

150) Wong WM, Lam SK, Wang WH, Lau GK, Kung NN, Chu KM, Lai KC, Hu WHC, Hu
FL, Liu XG, Yuen MF, Wong BC.
Three-day lansoprazole quadruple therapy for Helicobacter pylori positive duodenal
ulcers: a randomized controlled study
Poster presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120: 5 (suppl 1): A582

151) Zhang GS, Talley NJ, Henweek C, Ma Wyatt J, Wong BC, Lam SK, Xia B, Xia HHX.
Topographic association of Ki-67 and bcl-2 expression with H. pylori infection, gastric
atrophy, intestinal metaplasia: a role for antralization in gastric carcinogenesis.
Poster presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120: 5 (suppl 1): A656
 134 BCY Wong - 18 August, 2010

152) Zhou XM, Lai KC, Lam S, Zhang HB, Huang X, Fan XM, Hui W, Fan DM, Wong BCY.
Induced gastric mucosal apoptosis in Helicobacter pylori positive patients taking low
dose aspirin: a 6-month case-control study
Poster presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120: 5 (suppl 1): A598

153) Jiang XH, Lam SK, Fung HF, Lin CM, Koki AT, Masferrer JL, Xia HHX, Wong BCY.
Overexpression of protein kinase C-beta 1 isoenzyme suppresses SC-236 –induced
apoptosis in gastric cancer cells.
Poster presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120: 5 (suppl 1): A664

154) Lai KC, Lam SK, Chu KM, Hui WM, Wong CY, Hu W, Wong WM, Yuen MF, Chan
OO, Lai CL, Lau KK, Chan CK.
H. pylori eradication vs. combined proton pump inhibitor and H. pylori eradication in the
prevention of recurrent peptic ulcer complications in high-risk patients receiving low-
dose aspirin
Oral presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120(5): 550 (Suppl 1): A104

155) Lai KC, Chu KM, Hui WM, Wong CY, Hu W, Wong WM, Yuen MF, Chan OO, Lai CL,
Lau KK, Chan CK, Lam SK.
COX-2 inhibitor compared with proton pump inhibitor in the prevention of recurrent
ulcer complications in high risk patients taking NSAIDs.
Oral presentation, Digestive Disease Week, Atlanta, USA, May 2001
Gastroenterology 2001; 120: 5 (suppl 1): A104

156) Fung MYF, Wong WM, Lam SK, Yee YK, Hung WK, Yip WC, Szeto ML, Tong TSM,
Lai KC, Hu WHC, Yuen MF, Hui CK, Wong BCY.
Rabeprazole based 3-day and 7-day triple therapy vs. 7-day omeprazole based triple
therapy for the treatment of Helicobacter pylori infection
J Gastroenterol Hepatol 2001; 16 (9 suppl): A127.

157) Tang VSY, Wong WM, Lam SK, Lai KC, Hu WHC, Wong BCY
An evaluation of pyloritek test for the diagnosis of Helicobacter pylori infection in
Chinese- before and after eradication therapy.
J Gastroenterol Hepatol 2001; 16 (9 suppl) : A107.

158) Wong KW, Wong WM, Lam SK, Li TM, Cheung KL, Fung FMY, Xia HHX, Wong
BCY.
Low dose 13C-urea breath test with citrate is equally reliable for the detection of
Helicobacter pylori infection in Chinese
J Gastroenterol Hepatol 2001; 16 (9 suppl): A121.

159) Jiang XH, Lin MCM, Lam SK, Kung HF, Jiang XH, Koki AT, Masferrer JL, Wong BCY.
Inhibition of tumour promoter-induced activator protein 1 activation and cell
transformation by a specific COX-2 inhibitor, SC236
 135 BCY Wong - 18 August, 2010

J Gastroenterol Hepatol 2001; 16 (9 suppl): A120.

160) Wong BCY, Jiang XH, Lam SK.

Cyclooxygenase and gastric cancer
Journal of Modern Digestion and Intervention 2001: 6 (6); 23-25

161) Chan AOO, Lam SK, Wong CY, Hui WM, Kwong YL.
Methylation of E-cadherin gene in gastric cancer and in normal gastric mucosa from patients
with and without Helicobacter pylori infection
Hong Kong Practitioner 2002;24 (2 Suppl): 9

162) Hia HHX, Wong BCY, Huang XR, He XX, Wong WM, Leung SY, Yuen ST, Lan HY,
Lam SK.
Expression of Macrophage Migration Inhibitory Factor in Helicobacter pylori induced
gastritis and peptic ulcer disease
Hong Kong Practitioner 2002;24 (2 Suppl): 41

163) Lai KC, Cho CH, Hui WM, Hu HC, Wong CY, Lam SK
A study on the effect of COX-2 inhibitors on gastric mucosal prostaglandin synthesis
Hong Kong Practitioner 2002;24 (2 Suppl): 42

164) Wong WM, Mandir N, Goodlad RA, Wong BCY, Garcia SB, Lam SK.
Histogenesis of human colorectal adenomas and hyperplastic polyps –the role of cell
proliferation and crypt fission.
Hong Kong Practitioner 2002;24 (2 Suppl): 43.

165) Wong WM, Wong BCY, Tang VSY, Wong KW, Li TM, Cheung KL, Fung FMY, Lai KC,
Hu WHC, Chan CK, Xia HHX, Lam SK
Evaluation of three near patient tests for the diagnosis of Helicobacter pylori infection in
Chinese population
Hong Kong Practitioner 2002;24 (2 Suppl): 43

166) Wong WM, Lai KC, Lau CP, Hu WHC, Chen WH, Wong BCY, Hui WM, Wong YH, Xia
HHX, Lam SK
Upper gastrointestinal evaluation of Chinese patients with noncardiac chest pain
Hong Kong Practitioner 2002;24 (2 Suppl): 44

167) Wong BCY, Wu J

Different approaches of incorporating TCM in treatment of gastrointestinal diseases
Proceeding, TWGHs-HKU Eddie Wang Chinese Medicine Symposium, p47. Hong Kong,
February 2-3, 2002

168) Wong BCY, Wu J

Different approaches of incorporating traditional chinese medicine in the treatment of
gastrointestinal diseases
Proceeding, Symposium in Medical Sciences, 21st Century Health Care in Hong Kong, A
new era. June 1-2, 2002.
 136 BCY Wong - 18 August, 2010

169) Jiang XH, Lam SK, Tu SP, Lin MCM, Kung HF, Wong BCY.
Specific COX-2 inhibitor suppresses anchorage-independent cell growth through AP-
1/MAPK pathway in gastric cancer. (oral presentation)
Gastroenterology 2002; 122(4 Suppl 1): A3

170) Tu SP, Lam SK, Jiang XH, Lin MCM, Kung HF, Wong BCY.
Targeting survivin induced apoptosis and sensitized gastric and colon cancer cells to
chemotherapy. (oral presentation)
Gastroenterology 2002; 122(4 Suppl 1): A684.

171) Chan AOO, Lam SK, Wong BCY, Hui WM, Kwong YL.
Methylation of E-cadherin gene in gastric cancer and in normal gastric mucosa from
patients with and without Helicobacter pylori infection.
Gastroenterology 2002; 122(4 Suppl 1): A238.

172) Jiang XH, Lam SK, Fan XM, Lin MCM, Kung HF, Wong BCY.
Specific COX-2 inhibitor suppresses NF-kB activation by inhibition of RelA/p65 nuclear
translocation in gastric cancer.
Gastroenterology 2002; 122(4 Suppl 1): A240.

173) Tu SP, Jiang XH, Lam SK, Lin MCM, Kung HF, Wong BCY
Effect of hydroxycamptothecin and arsenic trioxide on expression of IAP-family genes in
gastric and colon cancer cells.
Gastroenterology 2002; 122(4 Suppl 1): A243

174) Gu Q, Wong WM, Lam SK, Yin Y, Wang WH, Fung F, Lai KC, Xia H, Wong BCY, Xiao
SD.
One week omeprazole, furazolidone and amoxycillin rescue therapy after failure of
Helicobacter pylori eradication with standard triple therapies.
Gastroenterology 2002; 122(4 Suppl 1): A586.

175) Wong WM, Gu Q, Lam SK, Fung FMY, Lai KC, Xia HHX, Hu WHC, Wong BCY.
Randomized controlled trial of rabeprazole, levofloxacin and rifabutin triple therapy versus
rabeprazole-based quadruple thearpy as a rescue treatment for failure of Helicobacter pylori
eradication with standard triple therapies.
Gastroenterology 2002; 122(4 Suppl 1): A587.

176) Wong BCY, Lam SK, Wong WM, Feng RE, Zheng TT, Yuen ST, Ho J, Leung SY, Chen
JS, Lai KC.
Eradication of Helicobacter pylori infection significantly slows down the progression of
precancerous lesions in high risk population: a 5-year prospective randomized study.
Gastroenterology 2002; 122(4 Suppl 1): A588.
Citation: 11

177) Wong BCY, Lam SK, Wong WM, Zheng TT, Chen JS, Chen BW, Lai KC, Yuen ST, Ho J.
 137 BCY Wong - 18 August, 2010

Eradicating Helicobacter pylori infection in general population prevents gastric cancer: a

7 year prospective randomized placebo-controlled study.
Gastroenterology 2002; 122(4 Suppl 1): A588.

178) Wong BCY.

Prevention of gastric cancer through eradication of Helicobacter pylori infection.
Annals of Oncology 2002; 13 (Suppl 5): 5-6.

179) Wong BCY.

Chemoprevention
Asian Journal of Surgery 2003; 26(1 Suppl): S31.

180) Chan AOO, Lam SK, Wong BCY, Wong WM, Yuen MF, Yuen YK, Hui WM, Rashid A,
Kwong YL.
Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter
pylori infection and in gastric cancer.
Asian Journal of Surgery 2003; 26(1 Suppl): S47.

181) Jiang XH, Wong BCY, Lin MCM, Tu SP, Kung HF, Lam SK.
Inhibition of anchorage-independent cell growth and activator protein-1 activation by
specific COX-2 nihibitor.
Asian Journal of Surgery 2003; 26(1 Suppl): S56
18th world congress in conjunction with 9th Hong Kong international cancer congress. P43

182) Yang Y, Xia HHX, Lam SK, Wong WM, Lai KC, Hu WHC, Chan CK, Cheung HKL,
Leung SY, Yuen ST, Wong BCY.
Gastric epithelial expression of trefoil family factor 2 and mucin 6 in normal and
Helicobacter pylori infected subjects.
Hong Kong Med J 2003; 9(1 Suppl) : 45

183) Wong WM, Gu Q, Lam SK, Fung FMY, Lai KC, Hu WHC, Yee YK, Chan CK, Xia HHX,
Yuen MF, Wong BCY.
Randomized controlled study of rabeprazole, levofloxacin and rifabutin triple therapy
versus quadruple therapy as seond-line treatment of Helicobacter pylori infection.
Hong Kong Med J 2003; 9(1 Suppl) : 46

184) Wong WM, Lam KF, Hui WM, Lai KC, Hu WHC, Lam CLK, Wong NYH, Xia HHX,
Chan AOO, Lam SK, Wong BCY.
A validated symptoms questionnaire (Chinese-GORDQ) for the diagnosis of gastro-
esophageal reflux disease in Chinese population.
Hong Kong Med J 2003; 9(1 Suppl) : 48

185) Wong WM, Lam SK, Hui WM, Lai KC, Chan CK, Hu WHC, Xia HHX, Hui CK, Yuen
MF, Chan AOO, Wong BCY.
Long term prospective followup of endoscopic esophagitis in southern Chinese –
prevalence and spectrum of the disease
Hong Kong Med J 2003; 9(1 Suppl) : 48
 138 BCY Wong - 18 August, 2010

186) Chan AOO, Chu KM, Lam SK, Wong BCY, Kwok KF, Law S, Hui WM, Yuen YH, Wong
J.
Soluble E cadherin is an independent pre-therapeutic factor for long term survival in gastric
cancer.
Hong Kong Med J 2003; 9(1 Suppl) : 52.

187) Wong WM, Lam SK, Cheung KL, Tong TSM, Rozen P, Young GP, Chu KW, Ho J, Law
WL, Tung HM, Choi HK, Lee YM, Lai KC, Hu WHC, Chan CK, Yuen MF, Wong BCY.
Evaluation of an automated immunochemical faecal occult blood test for colorectal
neoplasia screening in a Chinese population
Hong Kong Med J 2003; 9(1 Suppl) : 53

188) Tu SP, Cui JT, Lin MCM, Jiang XH, Yang Y, Lum CT, Yuen ST, Leung SY, Lam SK,
Kung HF, Wong BCY.
Restoration of XAF1 expression inhibits gastric and colonic tumorigenesis in vivo
Hong Kong Med J 2003; 9(1 Suppl) : 54

189) Xia HHX, He XX, Lam SK, Yang Y, Lin MCM, Wong WM, Kung HF, Leung SY, Yuen
ST, Wong BCY.
Increased serum levels and epithelial expression of macrophage migration inhibitory factor
in gastric cancer.
Hong Kong Med J 2003; 9(1 Suppl) : 54

190) Ye YN, Liu ESL, Shin VY, Wong BCY, Yuen ST, Cho CH.
Mechanism of inflammation-associated colonic tumorigenesis promoted by cigarette
smoking.
Hong Kong Med J 2003; 9(1 Suppl) : 55

191) Wong WM, Lam SK, Hui WM, Lai KC, Hu WHC, Lam KF, Lam CLK, Wong NYH, Xia
HHX, Chan AOO, Wong BCY.
Prevalence and clinical spectrum of gastroesophageal reflux disease in Chinese
population – a population based study.
Hong Kong Med J 2003; 9(1 Suppl) : 56.

192) Tu SP, Cui JT, Jiang XH, Yang Y, Lin MCM, Xu RA, Lam SK, Kung HF, Wong BCY.
Gene therapy for colon cancer using adeno-associated virus mediated survivin mutant.
Gastroenterology 2003; 124(4 Suppl 1): A34.

193) Lai KC, Lam SK, Wong B, Cheung R, Hui WM, Hu W, Wong WM, Chan OO.
Eradicationof H. Pylori in primary prevention of ulcer complications related to low-dose
asprin use.
Gastroenterology 2003; 124(4 Suppl 1): A93.

194) Wong WM, Lam SK, Hui, WM, Lai KC, Hu WHC, Lam KF, Lam CLK, Wong NYH, Xia
HHX, Chan AOO , Wong BCY.
Prevalence and clinical spectrum of gastroesophageal reflux disease in Chinese population
 139 BCY Wong - 18 August, 2010

- a population based study.

Gastroenterology 2003; 124(4 Suppl 1): A167.

195) Jiang XH, Lam SK, Lin MCM, Tu SP, Cui JT, Kung HF, Wong BCY.
Antisense targeting protein kinase C alpha inhibit gastric carcinogenesis in vivo.
Gastroenterology 2003; 124(4 Suppl 1): A185.

196) Xia HHX, He XX, Yang Y, Lin CMC, Wong WM, Kung HF, Ogura K, Berg DE, Zhao
YH, Wong BCY.
Helicobacter Pylori stimulates release of macrophage migration inhibitory factor in
monocytes through its pathogenicity island, but not related to CagA and CagE.
Gastroenterology 2003; 124(4 Suppl 1): A269.

197) Jiang XH, Lin MCM, Lam SK, He H, Tu SP, Kung HF, Wong BCY.
Nonsteroidal anti-inflammatory drugs inhibit human telomerase reverse transcriptase
(hTERT) in gastric and colon cancer.
Gastroenterology 2003; 124(4 Suppl 1): A288.

198) Tu SP, Cui JT, Lin MCM, Jiang XH, Yang Y, Lum CT, Yuan ST, Leung SY, Lam SK,
Kung HF, Wong BCY.
Restoration of XAF1 expressoin inhibits gastric and colonic tumorigenesis in vivo.
Gastroenterology 2003; 124(4 Suppl 1): A294.

199) Yang Y, Xia HHX, Talley NJ, Zhang GS, Wyatt JM, Adams S, Cheung K, Lam SK, Wong
BCY.
Antralizatoin of gastric incisura is topographcially associated with increased gastric
epithelial apoptosis and proliferation, but not with CagA seropositivity.
Gastroenterology 2003; 124(4 Suppl 1): A464.

200) Wong WM, Lam SK, Lam KF, Hui WM, Lai KC, Hu WHC, Lam CLK, Wong NYH, Xia,
HHX, Chan AOO, Wong BCY.
A validated symptom questionnaire (Chinese-GERDQ) for the diagonsis of
gastroesophageal reflux disease in Chinese population.
Gastroenterology 2003; 124(4 Suppl 1): A540.

201) He XX, Xia HHX, Yang Y, Lam SK, Lin MCM, Wong WM, Kung HF, Leung SY, Yuen
ST, Zhao YH, Wong BCY.
Increased serum levels and epithelial expression of macrophage migration inhibitory
factor in gastri cancer.
Gastroenterology 2003; 124(4 Suppl 1): A556.
Citation: 1

202) Yang Y, Xia HHX, Lam SK, Wong WM, Leung SY, Yuen ST, Elia G, Wright NA, Wong
BCY.
Helicobacter Pylori infection is associated with aberrant expression of Trefoil family
factor 2 and Mucin 6 in gastric antrum, incisura and body.
 140 BCY Wong - 18 August, 2010

Gastroenterology 2003; 124(4 Suppl 1): A588.

203) He XX, Xia, HHX, Yang Y, Lam SK, Lin MCM, Wong WM, Kung HF, Ogura K, Berg DE,
Zhao YH, Wong BCY.
Macrophage migration inhibitory factor released by monocytes after co-culture with
Helicobacter Pylori increases proliferation of gastric epithelial cells.
Gastroenterology 2003; 124(4 Suppl 1): A594.

204) Chan AOO, Chu KM, Lam SK, Wong BCY, Kwok KF, Law S, Hui WM, Yueng YH,
Wong J.
Soluble E-cadherin is an independent pre-therapeutic factor for long term survival in
gastric cancer.
Gastroenterology 2003; 124(4 Suppl 1): A654.

205) Wong B.
FOBT – immunochemical or guaiac?
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A1.

206) Lam SK, Wong BCY.

The role of cyclooxygenase in gastrointestinal diseases
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A5.

207) Wong B
H. pylori eradication: does it prevent gastric cancer?
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A5.

208) Chan AOO, Lam SK, Wong CY, Hui WM, Kwong YL.
Methylation of E-cadherin gene in gastric cancer and in normal gastric mucosa from patients
with and without Helicobacter pylori infection
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A19.

209) Chan AOO, Wong BCY, Lan HY, Loke SL, Chan WK, Hui WM, Yuen YH, Ng I, Hou L,
Wong WM, Yuen MF, Luk JMC, Lam SK.
Deregulation of E-cadherin-catenin complex in precancerous lesions of gastric
adenocarcinoma
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A27.

210) Chan AOO, Chu KM, Lam SK, Wong BCY, Kwok KF, Law S, Hui WM, Yueng YH,
Wong J.
Soluble E-cadherin is an independent pretherapeutic factor for long term survival in gastric
cancer.
J Gastroenterol Hepatol 2003; 18 (9 Suppl): A27.

211) Tu SP, Cui JT, Jiang XH, Xu R, Lin MCM, Lam SK, Zou B, Jiang SH, Kung HF, Wong
BCY.
Gene therapy using adeno-associated virus-mediated surviving antisense inhibits
angiogenesis and tumour growth in colon cancer.
 141 BCY Wong - 18 August, 2010

J Gastroenterol Hepatol 2003; 18 (9 Suppl): A60

212) Xia HHX, He XX, Yang Y, Lam SK, Gu Q, Lin MCM, Wong WM, Kung HF, Ogura K,
Berg DE, Zhao YH, Wong BCY.
Macrophage migration inhibitory factor released by monocytes after co-culture with
Helicobacter pylori stimulates proliferation of gastric epithelial cells.
J Gastroenterol Hepatol 2003;18 (Suppl.):B116.

213) Yang Y, Xia HHX, Lam Wong WM, Cheung HKL, Leung SY, Yuen ST, Elia G, Wright
NA, Wong BCY.
Aberrant epithelial expression of trefoil family factor 2 and mucin 6 in Helicobacter
pylori-infected gastric antrum, incisura and body : a useful marker for antralization.
J Gastroenterol Hepatol 2003;18 (Suppl.):B108.

214) Chan A OO, Wong BCY

E-cadherin and gastric Cancer.
Frontiers in Biomedical Research, The University of Hong Kong December 12, 2003

215) Huang JQ, Wang WH, Zheng GF, Lam SK, Wong BCT
Prevention of gastrointestinal cancers with non-steroidal anti-inflammatory drugs.
Frontiers in Biomedical Research, The University of Hong Kong December 12, 2003

216) Xia HHX, Chu KM, Lam SK, Lin MCM, Yang Y, Chan AOO, Wong WM, Leung SY,
Yuen ST, Hsiang FK, Wong BCY
Serum macrophage migration inhibitory factor as a diagnostic and prognostic biomarker for
gastric cancer.
Frontiers in Biomedical Research, The University of Hong Kong December 12, 2003

217) Chan AOO, Peng JZ, Lam SK, Wong Wm, Yuen MF, Cheung HKL, Kwong YL, Rashid A,
Hui WM, Wong BCY.
Disappearing of promoter methylation of E-cadherin gene in gastric mucosa after
Helicobacter pylori eradication.
Proceedings, 9th Medical Research Conference, University of Hong Kong, 7 February 2004

218) Wang WH, Huang JQ, Zheng GF, Wong WM, Lam SK, Karlberg J, Xia HHX, Fass R,
Wong BCY.
Is PPI test an effective approach to diagnose gastroesophageal reflux disease in patients with
non cardiac chest pain? A meta-analysis
Proceedings, 9th Medical Research Conference, University of Hong Kong, 7 February 2004

219) Chan AOO, Peng JZ, Lam SK, Hui WM, Wong WM, Yuen MF, Kwong YL, Rashid A,
Wong BCY.
Reversal of E-cadherin promoter hypermethylation status after helicobacter pylori
eradication.
Gastroenterology 2004: 126(4 Suppl 2):333
 142 BCY Wong - 18 August, 2010

220) Yang Y, Lin MCM, Ching YP, Lam SK, Xia HHX, Tu SP, Zou B, Wang JD, Li GQ, He H,
Gu Q, Peng JZ, Kung HF, Wong BCY.
FHL2 as a co-factor of XAF1 in the induction of apoptosis.
Gastroenterology 2004: 126(4 Suppl 2): S938

221) Wang JD, Gu Q, Xia HHX, Tu SP, Peng JZ, Yang Y, Zou B, Lin MCM, Kung HF, Lam SK,
Wong BCY.
JNK1 up-regulates the expression of XIAP-assoicated factor (XAF1) by a P53-dependent
pathway in gastrointetinal cancer.
Gastroenterology 2004: 126(4 Suppl 2): M946.

222) Zou B, Lin MCM, Lam SK, Tu SP, Yang Y, Wang JD, He H, Peng JZ, Kung HF, Wong
BCY
Hypermethylation status around exon 1 of XIAP-associated factor 1 in human gastric and
colon cancer cell lines.
Gastroenterology 2004; 126(4 Suppl 2): T981.

223) Tu SP, Chan AOO, Lin MCM, Jiang XH, Lam SK, Kung HF, Wong BCY.
Livin, a novel member of inhibitor of apoptosis, is marker of poor prognosis in gastric
cancer.
Gastroenterology 2004; 126(4 Suppl 2): T1256.

224) Wong WM, Lai KC, Hui WM, Hu WHC, Huang JQ, Wong NYH, Xia HHX, Chan AOO,
Lam SK, Wong BCY.
Pathophysiology of gastro-oesophageal reflux diseases in Chinese – role of transient lower
oesophageal sphincter relaxation and oesophageal motor dysfunction.
Gastroenterology 2004: 126(4 Suppl 2): T1724.

225) Li GQ, Xia HHX. Chen MH, Peng JZ, Gu Q, Cui JT, Cho CH, Lam SK, Lin MCM, Berg
DE, Feng ZH, Langenbach R, Kung HF, Wong BCY.
Cyclooxygenase-2 gene distruption enhances gastric inflammation but inhibits gastric
epithelial proliferation induced by H. pylori infection.
Gastroenterology 2004; 126(4 Suppl 2): W907

226) Wong BCY

Atypical manifestations of GERD
Med J Malaysia 2004; 59 (June) Suppl C, 12.

227) Wong BCY

Colorectal cancer screening and surveillance
Med J Malaysia 2004; 59 (June) Suppl C, 23.

228) Wong BCY

Targeting Inhibitor of Apoptosis proteins in treatment of cancer
Proceedings, Frontiers in Biomedical Research, University of Hong Kong, Dec 2004.

229) Wong BCY

 143 BCY Wong - 18 August, 2010

Targeting the inhibitor of apoptosis proteins in cancer treatment

Proceedings, The Croucher Advanced Study Institute “Molecular genetics and cell
signalling in cancers” January 17-21, 2005.

230) Lai KC, Hui WM, Wong BCY, Hu WHC, Chan AOO, Lam SK.
Lansoprazole but not Rofecoxib reduced dyspeptic symptoms of patients on NSAIDs.
Gastroenterology 2005; 128 (4 Suppl 2): A24.

231) Chan AOO, Chu KM, Sun YW, Cheung HKL, Lam SK, Yuen MF, Hui WM, Wong
BCY.
The association between Interleukin 1 beta polymorphism and hypermethylation at
tumor suppressor genes in gastric cancer.
Gastroenterology 2005; 128 (4 Suppl 2): A399.

232) Wang JD, Zou B, Gu Q, Jiang B, Zhuang Z, Xia H, Lin M, Lam SK, Kung HF, Wong
BCY.
Down-regulation of XAF1 expression by its interacting protein FHL2 via p53-mediated
transcription regulation.
Oral presentation, Digestive Disease Week, May 16, 2005, Chicago, USA.
Gastroenterology 2005; 128 (4 Suppl 2): A105.

233) Wang JD, Gu Q, He H, Jiang B, Zhuang Z, Xia H, Lin M, Lam SK, Kung HF, Wong
BCY.
Down-regulation of XIAP associated factor 1 (XAF1) through Hsf-1 binding in the
promoter region.
Oral presentation, Digestive Disease Week, May 16, 2005, Chicago, USA.
Gastroenterology 2005; 128 (4 Suppl 2): A105.

234) Zhu SL, Xia HHX, Lam SK, Yu LF, Yang Y, Sun YW, Wang JD, Chan AOO, Wong
BCY.
Alterations of gastric homeoprotein expression in H. Pylori infection and/or intestinal
metaplasia.
Gastroenterology 2005; 128 (4 Suppl 2): A598.

235) Xia B, Xia HHX, Lam SK, Chan AOO, Lai KC, Hu WHC, Wong BCY.
Trends in prevalence of peptic ulcer disease and Helicobacter pylori infection and
frequency of NSAID intake in general practitioner-referred dyspeptic patients over 6
years in Hong Kong.
Gastroenterology 2005; 128 (4 Suppl 2): A230.

236) Zhuang ZH, Tsao GSW, Xia HHX, He H, Chan AOO, Lam SK, Wong BCY.
COX-2 inhibition induces apoptosis in human esophageal epithelial cells: implication for
chemoprevention.
Gastroenterology 2005; 128 (4 Suppl 2): A299.

237) Fan XM, Zheng FS, Liu HY, Ma YH, Yu HF, Jiang M, Wong BCY
 144 BCY Wong - 18 August, 2010

Inhibition of Akt/PKB-cytochrome c by a COX-2 inhibitor induced apoptosis of gastric

cancer cell
Chinese J Digestive Diseases 2005; 6 (Suppl 1): A62.

238) Wong BCY

Eradication of Helicobacter pylori to prevent gastric cancer
Proceedings, 5th Shanghai International Conference of Gastroenterology, July 7-9, 2005,
Shanghai, PR China. pp81

239) Chan AOO, Wong BCY

Chemoprevention of colorectal cancer
Proceedings, 5th Shanghai International Conference of Gastroenterology, July 7-9, 2005,
Shanghai, PR China. pp126.

240) Wong BCY

Targeted therapies in gastrointestinal cancer
Proceedings, 10th Hong Kong Medical Forum, Department of Medicine, University of Hong
Kong, Hong Kong. 17 July 2005. pp26.

241) Yu LF, Wang JD, Zou B, Lin MCM, Wu YL, Wong BCY.
Sulindac Metabolites Induces XAF1 Expression by Inhibition of Extracellular Signal-
regulated Kinase 1/2 Phosphorylation in Human Gastric Cancer Cells.
Oral presentation, Asian Pacific Digestive Week 2005, Sept. 25-28, 2005, Seoul, Korea.
J Gastroenterol Hepatol 2005 Oct; 20: Supp. A299.

242) Gu Q, Xia HHX, Wang JD, Chan AOO, Lai KC, Chan CK, Yuen MF, Fung FMY, Wong
KW, Cheung HKL, Kung HF, Wong BCY.
Update on clarithromycin resistance in Helicobacter pylori in Hong Kong and its effect
on clarithromycin-based triple therapy
Poster presentation, Asian Pacific Digestive Week 2005, Sept. 25-28, 2005, Seoul,
Korea.
J Gastroenterol Hepatol 2005 Oct; 20: Supp. A160.

243) Zou B, Lin MCM, Lam SK, Tu SP, Zeng H, Yang Y, Wang JD, He H, Jiang SH, Kung
HF, Wong BCY.
Hypermethylation status around exon 1 of XIAP-Associated Factor 1 (XAF1) in human
gastric and colon cancer cell line.
Distinguished Poster Award, Asian Pacific Digestive Week, Sept. 25-28, 2005, Seoul,
Korea.
J Gastroenterol Hepatol 2005 Oct; 20: Supp. A370.

244) Zou B, Chim JCS, Lin MCM, Zeng H, He H, Yu LF, Sun YW, Jiang SH, Wong BCY
Correlation between the single-site CpG mutation within the gene promoter and the
expression silencing of XIAP -Associated Factor 1 (XAF1) in human colon cancer cell
lines.
Distinguished Poster Award, Asian Pacific Digestive Week, Sept. 25-28, 2005, Seoul,
Korea.
 145 BCY Wong - 18 August, 2010

J Gastroenterol Hepatol 2005 Oct; 20: Supp. A253.

245) Xia HHX, Wong WM, Chan AOO, Lam SK, Lai KC, Chan CK, Cheung HKL, Fung
FMY, Wong KW, Wong BCY.
Natural acquisition of Helicobacter pylori in adult dyspeptic patients with or without
previous infection – a 7-year follow-up study.
Australian Gastroenterology Week 2005, 19 October 2005, Australia.
J Gastroenterol Hepatol 2005 Oct, 20 Supp A112

246) Wong BCY

Chemoprevention of gastric cancer by eradication of Helicobacter pylori infection
2005 Autum Convention & Taipei Forum of Gastroenterology, Oct 1 2005, Taipei.
Gastroenterological Journal of Taiwan 2005 Sept; 22: 3: 260.

247) Wong BCY

Difficulties in colon cancer screening in Hong Kong.
Proceeding, 2005 International Asian conference of Cancer Screening, Nov 21-22, Taipei,
Taiwan, pp 102-103

248) Chan AOO, Jim MH, Lam KF, Siu DCW, Tong TSM, Ng FH, Hui WM, Chan CK, Lai KC,
Hu WHC, Yuen MF, Lau YK, Lee S, Lam SK, Wong BCY
Patients with coronary artery disease are at high risk for developing colorectal cancer and
adenoma: An interim analysis of a prospective study.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A36-A37 [no. 208] – Oral presentation

249) Chan AOO, Hui WM, Lam KF, Leung G, Hu WHC, Chan CK, Yuen MF, Lam SK, Wong
BCY
The clinical characteristics of patients with idiopathic constipation with a positive family
history.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A158 [no. S1123] – Poster presentation

250) Chan AOO, Hui WM, Hu WHC, Leung G, Chan CK, Yuen MF, Lam SK, Wong BCY
Familial aggregation in constipated subjects in a tertiary referral center
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A159-A160 [no. S1131] – Poster presentation

251) Yu LF, Wang JD, Zou B, Wu YL, Wong BCY

XAF1 mediates inhibition of extracellular signal-regulated kinase 1/2 induced apoptosis in
human colon cancer cells.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A531 [no. T1632] – Poster presentation

252) Chan AOO, Hui WM, Chan CK, Lai KC, Hu WHC, Yuen MF, Wong WM, Lau GKK, Hui
CK, Lam SK, Wong BCY.
Colonscopy demand and practice in a regional hospital over 9 years in Hong Kong: Resource
 146 BCY Wong - 18 August, 2010

implication for cancer screening.

Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A618 [no. W1025] – Poster presentation

253) Sun YW, Wang JD, Xia HHX, Zou B, Lin MCM, Kung HF, Wong BCY
Interferon-β-induced expression of XAF1 requires phosphorylation of STAT1 and a
sequential activation of protein kinase C and JNK in colon cancer.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA [poster presentation]
Gastroenterology 2006; 4 Suppl 2: A671 [no. W1505] – Poster presentation

254) Sun YW, Xia HHX, Zhu SL, Zou B, Lin MCM, Kung HF, Wong BCY
Novel interaction between xiap-associated factor 1 (XAF1) and nuclear coactivator CBP in
colon cancer.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA Poster of Distinction Award.
Gastroenterology 2006; 4 Suppl 2: A680 [no. W1551] – Poster presentation

255) Chan AOO, Chu KM, Leung SY, Huany C, Sun YW, Ko S, Yuen MF, Xia HHX, Cho CH,
Hui WM, Lam SK, Rashid A, Wong BCY
Helicobacter Pylori infection, interleukin 1 beta polymorphism and predisposition to gastric
cancer through the CpG island methylation pathway.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A717 [no. W1730] – Poster presentation

256) Tang LP, Cho CH, Hui WM, Huang C, Lai CL, Xia HHX, Lam SK, Rashid A, Wong BCY,
Chan AOO
A negative correlation between IL-6 and DNA methylation in patients with gastric cancer.
Digestive Disease Week 2006, 20-25 May, Los Angeles, USA
Gastroenterology 2006; 4 Suppl 2: A717 [no. W1731] – Poster presentation

257) Wong BCY

Randomized trials in China.
In Proceedings, International Symposium of 92nd Annual Meeting of Japanese Society of
Gastroenterology. April 20-21, 2006, pp 27

258) Wong BCY

Dyspepsia is not a universal diagnosis for patients with epigastric pain
In Proceedings: 11th Hong Kong Medical Forum, Hong Kong Convention & Exhibition
Center, 3-4 June 2006. pp18.

259) Wong BCY

Chemoprevention of gastric cancer with aspirin: bench to bedside
Proceedings, 4th International Society of Gastroenterological Carcinogenesis Conference,
August 24-26, 2006, Hawaii, USA.

260) Wong BCY

Use of COX inhibitors in prevention of gastric cancer
 147 BCY Wong - 18 August, 2010

In Proceedings, 3rd annual conference, Organisation for Oncology and Translational

Research, September 22-23, 2006, Hong Kong, pp33.

261) Wong BCY

Diagnosis of GERD: Is clinical profile enough?
Proceedings: Asian Pacific Digestive Week 2006, November 26-29, 2006,
Cebu City, Philippines.

262) Wong BCY

Chemoprevention of gastric cancer with aspirin: bench to bedside
Proceedings, Frontiers in Biomedical Research HKU 2006, 8 December 2006. Hong Kong,
pp 40-41.

263) Wong BCY

Management of high grade dysplasia in Barrett’s esophagus
Proceedings, GIHep Singapore, 22nd Annual Scientific Meeting, 2 March 2007, pp 26.

264) Chan AOO, Hui WM, Wong NYH, Leung G, Lam SK, Wong BCY
Decreased cortical activation during rectal distention in patients with functional
constipation with normal rectal compliance
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A23 [No. 119]

265) Chan AOO, Jim MH, Lam KF, Siu DCW, Tong T, Ng FH, Wong SY, Hui WM, Chan CK,
Lai KC, Cheung TK, Chan P, Wong G, Yuen MF, Lau YK, Lee S, Seto ML, Lam SK,
Wong BCY
Patients with coronary artery disease had high prevalence of colorectal cancer and adenoma:
END-results of metabolic syndrome and smoking.
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A65 [No. 381]

266) Chan AOO, Ng FH, Chang CM, Wong SY, Chu WM, Yuen WC, Lau YK, Cheung TK,
Wong BCY
Prevalence and prediction of gastrointestinal events in patients receiving a combination of
aspirin plus clopidogrel
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A135 [No. 916]

267) Chan AOO, Huang C, Leung G, Hui WM, Lam SK, Wong BCY
Familial constipation is associated with α2 adrenoceptor polymorphism
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A189 [No. S1177]

268) Chan AOO, Loo CK, Leung CM, Wong SY, Ng FH, Li MKW, Lam KM, Lam SK, Wong
BCY
Prevalence of colonic lesions after a negative screening colonscopy in a population with
 148 BCY Wong - 18 August, 2010

rapidly rising colorectal cancer incidence: A prospective multi-center analysis.

Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A189 [No. S1178]
Citation: 1

269) Chan AOO, Hui WM, Leung G, Wong NYH, Chan P, Hung IFH, Hsu A, But D, Lam SK,
Wong BCY
Better efficacy of tegaserod in constipated patients with slow colonic transit, absent pelvic
floor dyssynergy and absent impaired rectal sensation
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A194 [No. S1198]

270) Chan AOO, Hui WM, Leung G, Hu WHC, Lam SK, Wong BCY
Efficacy of tegaserod for functional constipation in Chinese subjects: A randomized double
blind controlled trial in a single center
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A194 [No. S1199]

271) Chan AOO, Jim MH, Lam KF, Siu DCW, Tong T, Ng FH, Wong SY, Hui WM, Lam SK,
Wong BCY
Aspirin does not prevent recurrence of colorectal adenomas in patients with coronary artery
disease
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A194 [No. S1201]

272) Chan AOO, Chow R, Hui WM, Leung G, Tong T, Lam SK, Wong BCY
Biofeedback is equally effective in patients with short or long duration of function
constipation
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A194 [No. S1202]

273) Lam TJ, Mulder CJJ, Peña S, Wong BCY, Hui WH, Lam SK, Chan AOO
Increased in prevalence of advanced colonic polyps in young patients over the past eight
years in Hong Kong
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A195 [No. S1207]

274) Dai Y, Qiao L, Gu Q, Xia HHX, Cheung TK, Ma J, Zou B, Wong BCY
Activation of Pparγ and inhibition of Xiap in human cancer cells: Synergistic effects on cell
proliferation, apoptosis, and tumorigensis
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A425 [No. M1973]

275) Cheung TK, Xia HHX, Wong BCY.

Helicobacter pylori eradication for gastric cancer prevention
92nd Annual Meeting of the Japanese-Society-of-Gastroenterology. APR 20-22, 2006
Fukuoka JAPAN
 149 BCY Wong - 18 August, 2010

Journal of Gastroenterology. 2007,42: 10-15.

276) Cheung TK, Lam B, Ip M, Wong NYH, Chan AOO, Lam SK, Wong BCY
Nocturnal reflux symptoms coorelate with respiratory events in patients with obstructive
sleep apnea
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A482 [No. T1173]

277) Cheung T.K., Lam B., Ip M.S.M., Wong Y.H., Chan A.O.O., Lam S.K. and Wong B.C.Y.
Nocturnal Reflux Symptoms Correlate with Respiratory Events in Patients with Obstructive
Sleep Apnea. , AGA Digestive Digestive Disease Week 2007, 2007

278) Qiao L, Gu Q, Dai Y, Shen Z, Liu X, Ma J, Wong BCY

XAF1 inhibits angiogenesis of mouse endothelial cells
Digestive Disease Week 2007, May 19-24 Washington DC, USA
Gastroenterology 2007; 132(4) Suppl 2:A638 [No. T2187]

279) Wong BCY

Helicobacter pylori treatment and related chemoprevention of gastric cancer in the elderly.
Scientific sessions handouts, pp 397-398.
Digestive Disease Week 2007, May 19-24 Washington DC, USA.

280) Wong BCY

Eradication of H. pylori: is it necessary for gastric cancer prevention?
Proceedings, 13th Annual meeting of the Japanese Society for Helicobacter Research,
Biwako, Japan, 21-22- June, 2007, pp38.

281) Tse MK, Wong BCY, Sze KH.

Structural and functional study of XAF1, identification and characterization of a 13 kDa
structural domain. The 4th joint conference of the Hong Kong Biophysical Society and the
Guangdong Biophysical Society, HKUST, January 27, 2007.

282) Tse MK, Wong BCY, Sze KH.

Biophysical Characterization of a 13kDa Structural Domain in XAF1 Protein.
Fifteenth Symposium on Chemistry Postgraduate Research in Hong Kong, The University
of Hong Kong, April 26-28, 2008, A&E-20

283) Tse MK, Wong BCY, Sze KH.

Structural and Functional Study of XIAP-Associated Factor 1 (XAF1) - Identification and
Characterization of a 13kDa Structural Domain , 16th Triennial Conference for the
International Society of Magnetic Resonance, Kenting, Taiwan, October 14-19, 2007, P1-17

284) Tse MK, Wong BCY, Sze KH.

Structural and function Stude of XIAP-Associated Flactor1 (SFA__P), International
Conference in Structural Biology, The Chinese University of Hong Kong, Hong Kong,
November 19-22, 2007, A37.
 150 BCY Wong - 18 August, 2010

285) Wong LW, Zhu SL, Zhang SY, Lan XR, Chung ACK, Zhang R, Lam SK, Wong BCY, Xia
HHX, Lan HY.
MIF knockout mice are protected against Helicobacter pylori induced gastritis, 12th Medical
Research Conference, Department of Medicine, University of Hong Kong, 3 Feb, 2007.

286) Wong BCY.

Human Intervention trials on Helicobacter pylori and gastric cancer.
Proceedings of 66th Annual Meeting of the Japanese Cancer Association, Yokohama, Japan,
3 Oct, 2007.

287) Wong BCY.

Eradication of H pylori: is it necessary for gastric cancer prevention?
Proceedings of Asian Pacific Digestive Week, Kobe, Japan, 15-18 October 2007.
J Gastroenterol Hepatol 2007 Oct, Vol 22 Supp 2, pp A64.

288) Wong BCY.

Prevalence of GERD in southeast Asian countries.
Proceedings of Asian Pacific Digestive Week, Kobe, Japan, 15-18 October 2007.
J Gastroenterol Hepatol 2007 Oct, Vol 22 Supp 2, pp A107.

289) Zou B, Yang Y, Zeng H, Wong LW, Jiang SH, Wong BCY.
New function of Krit 1 and as a new interactor of XAF1 in colon cancer.
Proceedings of Asian Pacific Digestive Week, Kobe, Japan, 15-18 October 2007.
J Gastroenterol Hepatol 2007 Oct, Vol 22 Supp 2, pp A162.

290) Wong BCY

Targeted therapy in GI cancers.
Proceedings of Annual scientific meeting of The Federation of Medical Societies of Hong
Kong, Hong Kong, 20 October 2007.

291) Wong BCY

Eradication of H pylori for gastric cancer prevention.
Proceedings of Cross Straits Digestive Forum, Xiamen, PR China, 17 November 2007.
Chinese Journal of Gastroenterology 2007; 12 (suppl): S14.

292) Wong BCY

H. pylori eradication in the prevention of gastric cancer
Proceedings, Sixth Annual AACR international Conference: Frontiers in Cancer Prevention
Research, Philadelphia, USA, 5-8 December 2007; pp 172.

293) Wong BCY

Molecular targets of GI cancer
Proceedings, Frontiers in Biomedical Research, HKU 2007, 13 December 2007. pp60-61.

294) Fung J, But D, Hsu A, Cheng C, Hung I, Seto W, Wong BCY, Lai CL, Yuen MF.
Increase in liver stiffness measurements in severe hepatitis B flares
Journal of Hepatology. 2008; 48 Supp 2: S242-S242
 151 BCY Wong - 18 August, 2010

295) Ma J, Chen MH, Liang YJ, Gu Q, Wang J, Qiao L, Dai Y, Zou B, Lan HY, Wong BCY.
Pancreatic-duodenal homeobox 1 (PDX1) functions as a tumor suppressor in gastric cancer.
Digestive Disease Week 2008, May 17-22 San diego, USA
Gastroenterology. 2008; 134 (4) Supp1:A382.

296) Qiao L, Li GHY, Dai Y, Li ZS, Zou B, Ma J, Lin MCM, Wong BCY.
Gene expression profile in colon cancer cells in response to troglitazone: Impact of XIAP
expression.
Digestive Disease Week 2008, May 17-22 San diego, USA
Gastroenterology. 2008; 134 (4) Supp1:A384.

297) Zou B, Pang R, Qiao L, Wong L, Ma J, Wang Y, Zeng H, Lan HY, Wong BCY.
XIAP-associated factor 1 (XAFI) regulates p53-mediated apoptosis by a negative feedback
loop.
Digestive Disease Week 2008, May 17-22 San diego, USA
Gastroenterology. 2008; 134 (4) Supp1:A386.

298) Li ZS, Qiao L, Dai Y, Zou B, Ma J, Lan HY , Wong BCY.

Role of cIAP2 in gastric cancer.
Digestive Disease Week 2008, May 17-22 San diego, USA
Gastroenterology. 2008; 134 (4) Supp1:A612.

299) Hui SK, Tse MK, Wong BCY. and Sze KH.
Structural and Funtional Study of a 9kDa a-heical Domain of BIR3-RING Linker Region in
XIAP Protein by NMR Spectroscopy.
Fifteenth Symposium on Chemistry Postgraduate Research in Hong Kong, The University
of Hong Kong, April 26-28, 2008, A&E21

300) Cheung TK, Lam B, Ip MSM, Kung R, Ng CYC and Wong BCY.
Gastro-esophageal reflux disease negatively impacted on asthma control, quality of life and
psychological status in Chinese asthma patients
13th Mecical Research Conference, Department of Medicine, HKU, 2008.

301) Pang RWC, Law WL, Poon JTC, Fan J, Choi CY, Poon RTP and Wong BCY.
Isolation and characterization of tumorigenic and metastatic cancer stem cells from human
colorectal cancer.
13th Medical Research Conference, Department of Medicine, HKU, 2008.

302) Pang RWC, Law WL, Poon JTC, Fan J, Choi CY, Poon RTP and Wong BCY.
Isolation and characterization of tumorigenic and metastatic cancer stem cells from human
colorectal cancer.
Inaugural William and Elizabeth Dabies Foundation Trust International Meeting, 2008.

303) Yuen RMF, Tanaka Y, Fong DYT, Fung JYY, Wong DKH, Yuen JCH, But D, Chan AOO,
Wong BCY, Mizokami M and Lai CL.
 152 BCY Wong - 18 August, 2010

Independent risk factors and predictive score for the development of hepatocellular
carcinoma in chronic hepatitis B
Journal of hepatology: the journal of the European Association for the Study of the Liver,
2008, S252.

304) Fung JYY, But DY, Hsu A, Cheng CTK, Hung IFN, Seto WK, Wong BCY, Lai CL and
Yuen RMF.
Increase in liver stiffness measurements in severe hepatitis B flares.
43rd Annual Meeting of the European Association for the Study of the Liver, Milan, Italy,
2008, S242.

305) Zhang R, Zhang SY, Lan XR, Wu Y, Szalai AJ, Wong BCY, Lau CP, Wu EX and Lan
HY.
C-reactive Protein Promotes Cardiac Fibrosis in Angiotensin II-Induced Hypertensive
Cardiovascular Diseases, Basic Cardiovascular Sciences Conference 2008- Heart Failure:
Molecular Mechanism, Therapeutic Targets,American Heart Association, Keystone, CO,
USA, July 28-31, 2008.

306) Wong BCY

H. pylori eradication in prevention of gastric cancer
Proceedings, Eighth International Conference of anticancer research, Greece, Oct 17, 2008.
Anticancer Research 2008 Sept-Oct; 28(5C): 3543.

307) Wong BCY

Screening and prevention of gastric cancer.
Proceedings, 2009 Gastrointestinal Cancers Symposium, January 15-17, 2009, USA

308) Gu Qing, Zhang Wenjing, Wang Jide, Ma Juan, Li Zesong, Lan Hui Y., Wong Benjamin
C.Y.
Identification of a functional p53 Responsive element within the promoter of XAF1 gene in
gastrointestinal cancer cells.
Poster of Distinction in Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A308.

309) Ma Juan, Wang Jide, Zou Bing, Li Zesong, Zhang Wenjing, Gu Qing, Dai Yun, Qiao Liang,
Lan Hui Y., Wong Benjamin C.Y.
Hypermethylation Attributes to PDX1 Expression Silencing in Human Gastric Cancer
Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A306.

310) Dai Yun, Qiao Liang, Chan Kwok Wah, Ma Juan, Zou Bing, Gu Qing, Wang Jide, Pang
Roberta, Lan Hui Y., Wong Benjamin C.Y.
Inhibitory Effect of Embelin On Colon Carcinogenesis Is Peroxisome Proliferator-Activated
Receptor γ (PPARγ)-Dependent.
Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A617.
 153 BCY Wong - 18 August, 2010

311) Wang Jide, Zhang Wenjing, Gu Qing, Li Zesong, Qiao Liang, Lan Hui Y., Wong Benjamin
C.Y.
XAF1 Induced Mitotic Catastrophe Through Modulation of G2/M Checkpoint and
Interaction with Checkpoint Kinase 1
Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A754.

312) Zhang Wenjing, Wang Jide, Zou Bing, Ma Juan, Gu Qing, Qiao Liang, Lan Hui Y., Wong
Benjamin C.Y.
FHL2 Promotes Epithelial Mesenchymal Transition in Colon Cancer Through Modulating
the Composition of E-Cadherin/β-Catenin Complex
Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A104.

313) Hung Ivan F, Chan Pierre, Hsu Axel, But David, Seto Walter Wai Kay, Chan Chi Kuen,
Wong Siu-Yin, Tong Teresa, Wong Benjamin C.Y.
Standard Clarithromycin-Based Triple Therapy Is Superior to Levofloxacin-Based Triple
Therapy As First-Line Treatment for Helicobacter pylori Eradication in a Chinese
Population
Digestive Disease Week 2009, May 31- Jun 4, Chicago, USA
Gastroenterology. 2009; 136 (5) Supp1:A150.

314) Wong BCY

How do clinicians do science
Proceedings. 2009 Southern Digestive Disease Forum and 5th National Academic Congress
on Intestinal Diseases, p 72-76.

315) Wong BCY

Treatment of Helicobacter pylori in prevention of gastric cancer
6th international conference of Gastroenterology, Shanghai, July 1-4, 2009.

316) Wong BCY

Eradication of H.pylori to prevent gastric cancer: Feasibility and Effectiveness
Asian Pacific Digestive Week 27-30 Sep 2009

317) Wong BCY

Prevention of gastric cancer: a global challenge
Sir David Todd Lecture, Proceedings, Annual Scientific Meeting, Hong Kong College of
Physicians, Hong Kong, 10-11 October 2009.
154 BCY Wong - 18 August, 2010
 155 BCY Wong - 18 August, 2010

CLINICAL SERVICE AND DEVELOPMENT

1. Physician in charge of Medical Oncology (Gastroenterology) Ward, Department of Medicine,
Queen Mary Hospital. 1997-
Administration and clinical service of medical oncology(Gastroenterology) specialty in
the Department.

2. Development, setting up of the Medical Oncology Ward, Queen Mary Hospital. 1997-
Planning, set up and development of a central area for medical oncology in-patient
treatment in the Department. Designated area for preparation of chemotherapy, training
of oncology nurses.

3. Setting up of the Helicobacter pylori clinic, Department of Medicine, Queen Mary

Hospital. 1994-
For diagnosis, counseling, treatment and follow up of Helicobacter pylori infection
carriers.

4. Setting up of the Gastrointestinal oncology clinic, Department of Medicine, Queen Mary

Hospital. March 1998-
For counseling, treatment and follow up of patients with gastrointestinal cancer.

5. Development of chemotherapy protocols for gastrointestinal cancer in Department of

Medicine, in conjunction with Department of Surgery. 1997-
 Development and implementing specific treatment protocol for advanced colon cancer
in Department of Medicine.
 Development and implementing specific treatment protocol for advanced inoperable
pancreatic adenocarcinoma in Department of Medicine in conjunction with
Hepatobiliary team of Department of Surgery. Implementation of multi-disciplinary
approach in pancreatic cancer patient care.
 Development of treatment protocol for advanced hepatocellular carcinoma in
Department of Medicine.