1 Drugs Acting on Autonomic Nervous System
Anticholinergic Drugs 3
6 Drugs Acting on Autonomic Nervous System
Preparations
1. Nicotine transdermal: NICOTINELL-TTS 10, 20, 30 cm2 patches releasing 7, 14, 21 mg nicotine per 24 hr
respectively. In those smoking > 20 cigarettes every day—start with 30 cm2 patch, shift to smaller patches every
3–5 days, treat for 3–4 weeks.
2. Nicotine chewing gum: NULIFE 1, 2, 4 mg chewing gum; In those smoking > 20 cigarettes/day—start with
4 mg gum chewed slowly for 30 min when urge to smoke occurs—gradually reduce to 2 mg gum and then 1 mg
gum. In less heavy smokers—start at lower doses.
Adrenergic Drugs 7
10 Drugs Acting on Autonomic Nervous System
12 Drugs Acting on Autonomic Nervous System
14 Drugs Acting on Autonomic Nervous System
Preparations
1. Timolol: Start with 0.25% eye drops BD, change to 0.5% drops in case of inadequate response. 0.5% OD as gel
forming solution. GLUCOMOL, OCUPRES, IOTIM, LOPRES 0.25% and 0.5% eye drops. TIMOLAST 0.5% gel
forming eye drops (long acting).
Timolol 0.5% + Latanoprost 0.005%: LAPROST PLUS, LATOCHEK-T eye drops.
2. Betaxolol: 0.5% topically in eye BD; OPTIPRES, IOBET, OCUBETA 0.5% eye drops.
3. Levobunolol: 0.5% topically in eye OD; BETAGAN 0.5% ophthalmic solution.
4. Dipivefrine: 0.1% topically in eye BD; PROPINE 0.1% eye drops.
5. Apraclonidine: 0.5–1.0% topically in eye; ALFADROPS-DS 1% eye drops.
6. Brimonidine: 0.2% topically in eye TDS;
ALPHAGAN-P, BRIMODIN-P 0.15% eye drops, IOBRIM 0.2% eye drops.
2 Autacoids and Related Drugs
18 Autacoids and Related Drugs
19. Mizolastine: 10 mg oral; ELINA 10 mg tab.
20. Ebastine: 10 mg oral; EBAST 10 mg tab.
21. Rupatadine: 10 mg oral; RUPAHIST 10 mg tab.
Note: For H2-Antagonists (H2-Antihistaminics) See p. 118, 119.
Drugs for Migraine 19
Prostaglandins (PGs) 21
Nonsteroidal Antiinflammatory Drugs/ Antipyretic-Analgesics 23
Antirheumatoid Drugs/Drugs for Gout 27
Sedative-Hypnotic Drugs 67
Antiepileptic Drugs 69
72 Drugs Acting on Central Nervous System
Antipsychotic Drugs 75
Drugs for Mania and Bipolar Disorder 77
Antidepressants 79
Antianxiety Drugs 81
18. Trazodone: 50–200 mg/day; TRAZODAC 25, 50 mg tab, TRAZONIL, TRAZALON 25, 50, 100 mg tabs.
19. Mianserin: 30–100 mg/day; TETRADEP 10, 20, 30 mg tab, SERIDAC 10, 30 mg tab.
20. Bupropion: 150–300 mg/day; SMOQUIT–SR, BUPRON–SR 150 mg tab.
21. Mirtazapine: 15–45 mg/day; MIRT 15, 30, 45 mg tabs, MIRTAZ 15, 30 mg tab.
22. Venlafaxine: 75–150 mg/day; VENLOR 25, 37.5, 75 mg tabs, VENIZ-XR 37.5, 75, 150 mg ER caps.
23. Tianeptine: 12.5 mg BD–TDS; STABLON 12.5 mg tab.
24. Amineptine: 100 mg BD at breakfast and lunch; SURVECTOR 100 mg tab.
25. Duloxetine: 30–80 mg/day; DELOK, DULANE, DUZAC 20, 30, 40 mg caps.
Opioid Analgesics and Antagonists 83
Preparations
Opioid Analgesics
1. Morphine: 10–50 mg oral, 10–15 mg i.m. or s.c., 2–6 mg i.v.; 2–3 mg epidural/intrathecal; children 0.1–0.2 mg/
kg i.m. or s.c. MORPHINE SULPHATE 10 mg/ml inj; MORCONTIN 10, 30, 60, 100 mg continuous release tabs;
30–100 mg BD; RILIMORF 10, 20 mg tabs, 60 mg SR tab.
CNS Stimulants and Cognition Enhancers 85
9 Drugs Affecting Blood
Coagulants 109
4. Folinic acid: 1–3 mg i.v.; CALCIUM LEUCOVORIN 3 mg/ml inj; FASTOVORIN 3 mg and 15 mg amps,
50 mg vial; RECOVORIN 15 mg tab, 15 mg and 30 mg vial for inj.
Erythropoietic factor
Recombinant human erythropoietin (Epoetin α, β): 25–100 IU/kg s.c./i.v. 3 times a week (max 600 IU/
kg/week);
HEMAX 2000 IU/ml and 4000 IU/ml vials; EPREX 2000 IU, 4000 IU and 10,000 IU in 1 ml prefilled syringes;
ZYROP (epoetin β) 2000 IU and 4000 IU vials.
Anticoagulants 111
Fibrinolytics/ Antifibrinolytics/Antiplatelet Drugs 113
6. Acenocoumarol (Nicoumalone): 8–12 mg followed by 2–8 mg/day; ACITROM, NISTROM 1, 2, 4 mg tabs.
7. Ethylbiscoum acetate: 900 mg followed by 300–600 mg/day.
8. Sodium citrate: 1.65 g for 350 ml of blood (for transfusion); ANTICOAGULANT ACID CITRATE DEXTROSE
SOLUTION 2.2 g/100 ml (75 ml is used for 1 unit of blood).
9. Sodium oxalate: 10 mg for 1 ml blood (for blood counts etc.).
10. Sodium edetate: 2 mg for 1 ml blood (for investigations).
116 Drugs Affecting Blood
Preparations
1. Lovastatin: 10–40 mg/day; ROVACOR, AZTATIN, LOVAMEG 10, 20 mg tabs.
2. Simvastatin: 5–20 mg/day (max 80 mg); SIMVOTIN, SIMCARD, ZOSTA 5, 10, 20 mg tabs.
3. Pravastatin: 10–40 mg/day; PRAVATOR 10, 20 mg tabs.
4. Atorvastatin: 10–40 mg/day (max 80 mg); AZTOR, ATORVA, ATORLIP 5, 10, 20 mg tabs.
5. Rosuvastatin: 5–20 mg/day (max. 40 mg/day); ROSUVAS, ROSYN 5, 10, 20 mg tab.
