1.
Compare and contrast the ionic concentrations of plasma, urine, intracellular and
extracellular fluids.
2. Describe the basic structural features of mRNA and explain the process of translation
from mRNA to protein in detail.
3. Using diagrams, explain the structure of alpha helices and beta pleated sheets.
4. Explain in detail any two forms of cellular transport of solutes/molecules between the
intracellular and extracellular space (Diagrams required).
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( 6 marks)
1. With the aid of a diagram, explain the main features of the DNA double helix.
2. Compare and contrast the roles of IgG and IgA antibodies.
3. Using graphs and diagrams, explain how enzymes reduce activation energy.
4. Differentiate between saturated and unsaturated fats. Why excessive consumption of
saturated fats and cholesterol is considered harmful to health?
5. Describe the mechanism by which hemoglobin loads and unloads oxygen.
6. Explain the importance of cofactors or coenzymes in enzyme catalysis with suitable
examples (any two examples).
7. Why is a diet high in fructose (e.g., High Fructose Corn Syrup) considered unhealthy?
Draw the structure of fructose.
8. Why are there around 41 tRNAs when there are 61 codons coding for amino acids (62 if
including selenocysteine)? Discuss the significance of the wobble position at the 5’ end of
the anticodon on tRNAs.
9. State the ‘Michaelis-Menten’ equation and define each term within the equation. (CO1)
10. Briefly describe the basic structure of an antibody, including a well-labeled diagram, and
indicate where antigen binding occurs.
11. How are enzymes classified? Illustrate each class with a general reaction and explain the
types of reactions they catalyze.
12. Draw and label the structures of two basic amino acids and two acidic amino acids found
in nature.