Hall Ticket No.. Code No.

ECD KFM 1102 01 23 1 R

ffiAMBffiA
s E co N D' *"'5iitXtfi ExA MrN Arr o N
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Time: 1O minutes Max. Marks -1O
Date: 19lOL/2023
PATHOLOGY- PAPER ONE

MULTIPLE CHOICE QUESTIONS (l mark each)

fnstructions: -

1. Enlargement of uterus in pregnancy is an example of

A. Apoptosis B. Hypoplasia
C. Metaplasia D. Hypertrophy

2. Example of type II hypersensitivity reaction

A. Myasthenia gravis B. Contact hypersensitivity
C. Tuberculosis D. Anaphylaxis

3, Special stain for Iron is

A. Masson Fontana B. Orcein
C. Oil red D. Perls

4. Preformed mediator in mast cell is

A. Arachidonic acid B. Platelet activating factor(PAF)

C. Histamine D. Prostaglandin

5. Agrres spatula is used for cytology of

A. Fluids B. Cervical smears
C. Sputum D. Bone marrow

6. Myeloperoxidase positivity favours

A. Lymphoid leukemia B. Megakaryocytic leukemia
C. Myeloid leukemia D. Erythroleukemia

P.T.O
7. isosthenuria is seen in
A. Chronic renal failure B. Diabetic nephropathy
C. Acute renal failure D. Glomerulonephritis

B. Cob web appearance in CSF is seen in.......... meningitis

A. Meningiococcal B. Streptococcal
C. Tuberculous D. Cryptococcal

9. Lines of zahn are seen in ....

A, Thrombus B. Embolus
C. Infarct D, Hyperemia

l-0. Causative agent of infectious mononucleosis is

A. Human Papilloma virus B, Cytomegalovirus
C. Enterovirus D. Ebstein Barr virus
 Hall Ticket No Code No. ECD KFM 1102 01 23 1 R

ffiam#ffi*
SECOND PROFESSIONAL MBBS DEGREE EXAMINATION
JANUARY/FEBRUARY - 2023
Time: 3 hrs Max. Marks -1OO
Date: 19lOL/2023
PATHOLOGY. PAPER ONE
Instructions: -
) Draw labeled diagrams/flow chart wherever necessary.

SECTION -A [45 Marks]

I. Multiple Choice Questions (Separate question paper and answer sheet attached
[1O Marks]
IL Structured Essay:
A. Define Neoplasia.
B. List the differences between benign and malignant neoplasms.
C. Mention the pathways of spread.
D. Mention four tumor markers.
[1+4+3+2 = 1O Marks]
III. Write briefly on:
A, Name four pigments
B. Two autosomal recessive disorders
C. Four factors influencing wound healing
D. Mention the types of shock
E. Name 2 diseases associated with Vit D deficiency
[2 marks each = 1O Marks]
IV. Write short notes on:
A. Phagocytosis
B. Amyloidosis
C. Types of embolism
D. Type IV hypersensitivity reactions
E. Necrosis
[5 marks each = 25 Marks]

P.T.O
 SECTION -B [45 Marks]
V. A 65 year old male presented with low backache, BP and fatigue, ESR'l-2Omm/I't hour
Xray skull showed lytic lessions

A. Give your diagnosis with reasons

B. List four relevant investigations to be done in this patient.
C. Describe the expected hematological picture.
D. Describe the changes in the organ systems mainly affected.
t1+2+4+3 = 10 Marksl
VI. Write briefly on;
A, What is leukemoid reaction?
B. Mention two causes of eosinophilia.
C, What are Auer rods?
D. Mention 2 RBC inclusions
E. List 2 complications of sickle cell anemia
[2 marks each = 1O Marks]
VIL Write Short notes on:
A. Hematocrit
B. Urinary sediments
C. Transfusion reactions
D. Hematological findings in megaloblastic anemia
E' Immune thrombocytopenic purpura
[5 marks eash = 25 Marks]
Hall Ticket No............. Code No. ECD KFM 1102 01 23 2 R

@AMRITA
qqvtsHwA
vTDYAPEETHAM
Y lU I
r4lEciarrl V lJt lYaIl

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION

JANUARY/ FEBRUARY- 2023
Time:3 hrs Max. Marks -1OO
Date: 21lOll2023
PATHOLOGY- PAPER TWO

Instructions; -
) Draw labeled diagrams/flow chart wherever necessary.

SECTION -A [45 Marks]

I Multiple Choice Questions (Separate question paper and answer sheet attached
[1O Marks]
II. A 55 year old chronic smoker presents with cough and blood stained sputum for four
months, There is h/o loss of weight and appetite.
A. What is your provisional clinical diagnosis?
B. Mention two tests to confirm the diagnosis
C. What are the four histological types?
D. Describe the morphology of this lesion
E. List 2 other causes of hemoptysis
[1+2+3+3*1 = 1O Marks]
IIL Write briefly on:

A. What is Libmann sacs endocarditis?

B. Four syndromes associated with Ca colon
C. Mention the four stages of lobar pneumonia
D. Four histopathological features of ulcerative colitis
E. Two complications of viral hepatitis
[2 marks each = 1O Marks]
IV. Write short notes on:

A. Valvular lesions in rheumatic heart disease

B. CSF findings in viral meningitis
C. Pleomorphic adenoma
D. Cirrhosis liver
E. Informed consent
[5 marks each = 25 Marks]

P.T.O
 SECTION -B [45 Marks]
v. A 65 year old lady with fixed hard lump in the left breast and nipple retraction
A. What is your provisional clinigal diagnosis?
B. Mention two tests to confirm the diagnosis
C. Describe the morphology of this lesion
D. Mention four prognostic factors
E. List 2 causes of blood stained nipple discharge
lL+2+4+2*1 = 1O Marksl
VI. Write briefly on:
A. Four germ cell tumors of testis
B. Two degenerative changes in leiomyoma
C. Premalignant lesions of skin
D. Mention 4 histopathology findings in Hashimoto's thyroiditis
E. Histological types of renal cell carcinoma
12 marks each = 1O Marksl
VII. Write Short notes on:
A. Osteoclastoma
B. Diabetic nephropathy
C. Basal cell carcinoma
D. Etiopathogenesis and morphology of cervical cancer
E' pathogenesis of rype II diabetes me'itus
[5 marks each = 25 Marks]
 Code No, ECD KFM 1102 01 23 2 R

@AMRITA
ffiVISHwA VIDYAPEETHAM

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION

JAN UARY/ FEBRUARY-2023

Time: 10 minutes Max. Marks -1O

Date:2L/OL/2023

PATHOLOGY- PAPER TWO

MULTIPLE CHOICE QUESTIONS [t mark each]

fnstructions: -

1. Call Exner bodies are seen in

A. Granulosa cell tumor B. Sertoli cell tumor
C. Fibrothecoma D. Teratoma

2. Helicobacter pylori is associated with

A. Carcinoma stomach B. MALToma
C. Gastric ulcer D. All of the above

3. Special stain useful for diagnosis of melanoma is ...

A. Masson Fontana B. Giemsa
C.Oil red O D. PAS

4. Sunburst appearance is seen in

A. Ewing's sarcoma B. Osteosarcoma
C. Osteoclastoma D. Osteoid

5. Staghorn calculus is associated with

A. Klebsiella B. Streptococci
C. E.Coli D. Proteus

6. Cambium layer is seen in

A. Angiosarcoma B.Rhabdomyosarcoma
C. Synovial sarcoma D.Fibrosarcoma

P.T.O
7. Flexner wintersteiner rosettes are seen in
A, Hepatoblastoma B. Neuroblastoma
C. Retinoblastoma D. Medulloblastoma

B. Most common cause of nephrotic syndrome in children is

A. Minimal change disease B. Membranous nePhroPathY
C. Focal segmental glomerulosclerosis D, Membranoprliferative glomerulonephritis

9. Peri neural invasion in mostly seen in....."'

A. Acinic bell carcinoma B' Adenoid cystic carcinoma
C. Mucoepidermoid carcinoma D' Oncocytoma

10. Causative agent of nasopharyngeal carcinoma is

A. Human paPilloma virus B. Cytomegalovirus
C, Rhino virus D. Ebstein Barr virus
Ha I Ticket No Code No. ECD KFM ll02 07 23 1 S

@AMRITA
ffivrsHwA vTDYAPEETHAM

SECOND PROFESSIONAL MBBS DEGREE EXAMINATTON

J U LYIAUG UST -2023[ SU PPLE M E NTARY]

Time: 1O minutes Max. Marks -1O

Date:18/O7/2023
PATHOLOGY. PAPER ONE

MULTIPLE CHOICE QUESTIONS (1 mark each)

Instructions: -

1. Red infarcts are typically seen in

A. Heart B. Kidney
C. Spleen D. Lung
2, The Hb types not found in a normal adult are
A. HbAand Hb F B, HbAand HbA2
C. HbSand HbC D. HbA2and HbF
3. Chronic venous congestion of liver is also called
A. Brown atrophy B. Nutmeg liver
C. Thrush breast liver D. Tabby cat liver
4. The buffy coat is composed of
A. Fat and white cells B. White cells and platelets
C. White cells and red cells D. White cells and plasma
5. Which of the following pairing is FALSE?
A. Rough endoplasmic reticulum-protein synthesis
B. Smooth endoplasmic reticulum-lipid & enzyme synthesis
C. Lysosome-contain hydrolase enzymes
D. Golgi apparatus-packaging of peroxisomes
6. Multiple myeloma is characterized by
A. Monoclonal gammopathy
B. Osteolytic bone lesion
C. Bone marrow infiltration by plasma cells
D. All of the above
7. Stag horn calculi in urine are
A. Calcium oxalate B. Triple phosphate
C. Urate D. Calcium carbonate

P.T,O
 organelles through the process
in which autosomes
B. The degradation of intracellularto f;;;;utophagoiysosomes is called
combine with primary rysosomes
A Aurophasy
C. HeteroPlasmy
B !il?[l|.l?r,,
mostly have
a general rule, familial disorders that involve abnormalities of enzymes
9,
" As
;l"i iYPe of inheritance Pattern?
B' Autosomal recessive
A. Mitochondrial D' Autosomal dominant
C. X-linked dominant
who develops a
10. A patient with malabsorption
subsequentlY develoP
B. Intestinal metaPlasia
A. Acute leukemia D. Night blindness
C. Megaloblastic anemia
Hall Ticket No... Code No. ECD KFM lIO207 23 1 S

@AMRITA
ffiVISHWA VIDYAPEETHAM

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION

JULY/AUGUST - 2023[SUPPLEMENTARYI
Time: 3 hrs Max. Marks -1OO
Date:18/O7/2023
PATHOLOGY. PAPER ONE
Instructions: -
> Draw labeled diagrams/flow chart wherever necessary.

SECTION .A
L Multiple Choice Questions (Separate question paper and answer sheet attached
[1O Marks]
II. Structured Essay:

A 55 year old man who is a chronic smoker complains of sudden increase in weight, O/e
he is found to have hypertension, moon facies and truncal obesity, An imaging revealed
a lesion in the lung
A. What is this phenomenon called and define it?
B. Define neoplasia and outline 5 differences between benign and malignant tumors
C. Outline the metastatic cascade
D. What are tumor suppressor genes and give 3 examples
[2+3+3+2 = 1O Marks]
IIL Write briefly on:
A. 2 mechanisms involved in peripheral tolerance
B. 4 mediators of inflammation
C. 4 cellular adaptations
D. Stages of shock
E. Virchows triad in pathogenesis of thrombosis
[2 marks each = 1O Marks]
IV. Write short notes on:
A. Morphology of apoptosis
B. Pathogenesis of amyloidosis
C. Healing by secondary intention
D. Free radical injury
E. Edema
[5 marks each = 25 Marks]
P.T.O
 SECTION -B

V A 10 year old boy has been lethargic for long and gives history of repeated blood
transfusions O/e he is pale, has a peculiar facies with frontal bossing and protruding jaw
and ultrasound shows hepatospelnomegaly. His hemogram showed Hb-7gm/dl,
P CV - 24o/o.MCV- 6 5 f I,TC -7 4OO/ mm3 a n d fe rriti n - 3 4 5 0 n g/ m
I

A. What will be your provisional diagnosis?

B. What will be the peripheral smear and bone marrow findings?
C. What is the defect and mode of inheritance?
D. What is the reason for the peculiar facies?
E. How will you confirm the diagnosis?
l2+3+2+t+2 = 1O Marksl
VI. Write briefly on:
A. 2 causes for eosinoPhilia
B. 2 cytological fixatives
C. 2 findings in peripheral smear in CML
D. 3 RBC inclusions
E. 2 translocations in leukemias
[2 marks each = 1O Marks]
VII. Write Short notes on:

A. Idiopathic thrombocytopenic purpura

B. Urine sediments
C. Classification of macrocytic anemia
D. Hodgkins lymphoma
E. Transfusion reactions
[5 marks each = 25 Marks]
Hall Ticket No Code No. ECD KFM 7lO2 07 23 2 S

@AA/\ratrA
ffivrsHwA vnlYAPEr-aHAl*'
SECOND PROFESSIONAL MBBS DEGREE EXAMINATION
JULY/AUGUST -2023 [SUPPLEM ENTARY]

Time: 1O minutes Max. Marks -1O

Date:2OlO7/2023

PATHOLOGY. PAPER TWO

MULTIPLE CHOICE QUESTIONS 1t mark eachl

Instructions: -

1. Skip lesions are features of

A. Crohn's disease B, Ulcerative colitis
C. Coeliac sprue D. Whipples disease

2. A 47-year old woman undergoes routine mammographic screening and there are multiple
small areas of increased density. An excisional breast biopsy yields a diagnosis of lobular
carcinoma. Which of the following is the most likely finding associated with this?
A. Opposite breast involvement B. Absent family history
C. Estrogen receptor negativity D. No residual carcinoma

3. A 70 year old man has had back pain for 4 months. Labs revealed total serum protein of
9.Sgm/dl with an albumin of 3gm/dl. Imaging reveals several lytic lesions in the vertebral
bodies. Which of the following cell types is likely to be numerous in the bone marrow
aspirate?
A. Giant cells B. Osteoblasts
B. Plasma cells D. Metastatic carcinoma cells

4. A 54 year old man has had malaise with a 6 kg weight loss over the past 7 months.
Laboratory studies show a positive serology for hepatitis B surface antigen and elevated
serum alpha-fetoprotein. Which of the following neoplasms is he most likely to have?
A. Hepatic adenoma B. Hepatocellular carcinoma
C. Hepatic hemangioma D. Metastatic carcinoma

P.T.O
 5. A 28 year old sexually active woman undergoes a routine examination. A biopsy of the
cervix is performed, and on microscopic examination shows cervical intraepithelial
neoplasia tit(Ctru lll) infection with which of the following organisms is most likely to cause
her disease?
A. Herpes simPlex B. HerPes zoster
C. Human papilloma virus D. Ebstein Barr
6. Trauma to the breast will cause what type of necrosis?
A. coagulative necrosis B. Liquefactive necrosis
C. Caseous necrosis D. Fat necrosis

7. Gastrointestinal stromal tumour(GIST) arises from which of the following?

A. Smooth muscte cell B, Nerve sheath cells
C. Interstitial cells of cajal D. Vascular endothelial cell

B. A 50 year old man has episodic headaches for 3 months O/e he is hypertensive. An
abdominal CT shows a 7cm left adrenal mass which when removed, showed a marked
rise in blood pressure. what is the most likely cause for this?
A. Increased catecholamines B. Decreased serum cortisol
C. Increased ACTH . Increased growth hormone

9. Following a bike accident, a 1B year old boy has progressively decreasing oxygen
saturation. He remains afebrile but dies 3 days later. At autopsy, the lungs show pink
hyaline membranes. Which of the following pulmonary diseases most likely complicated
his course?
A. Bronchopneumonla B. Chronic bronchitis
C. Diffuse alveolar damage D. Bronchiectasis

10. Ground glass hepatocytes and sanded nuclei are features of acute viral hepatitis caused by
A. HCV B. HBV
C. HAV D. HEV
 Hall Ticket No. Code No. ECD KFM LL02 07 23 2 S

@AMI{IY&
ffi; VISHWA VIDYAPEHTHAM
SECOND PROFESSIONAL MBBS DEGREE EXAMINATION
J U LylAUG UST- 2O23[SUppLEM E NTARY]
Time: 3 hrs Max. Marks -1OO
Dater 2OlO7 /2023
PATHOLOGY- PAPER TWO

Instructions: -
> Answer Section A and Section B in separate answer sheets
> Draw Iabeled diagrams/flow chart wherever necessary.
, Do not write anything on the question paper other than your Hall Ticket No on Top left.

SECTION -A
I' Multiple Choice Questions (Separate question paper and answer sheet attached
[10 Marks]
II. A 55 year old man develops sudden onset chest pain with profuse sweating. O/e his
pulse was rapid but weak. ECG reveals ST elevation and T wave inversion. The patient
expired 12 hours later.
A. What could be the probable diagnosis?
B. What biomarkers are useful in this condition?
C. What are the risk factors responsible for this?
D. What are the complications of this condition
[1+3+3+3 = 1o Marks]
III. write briefry on:
A. 3 complications of peptic ulcer disease
B. 4 risk factors in lung cancer
c. 3 extraintestinal manifestations of inflammatory bowel disease
D. 4 causes for cirrhosis
E. 3 prognostic factors in colorectal cancer
[2 marks each = 1O Marks]
IV. Write short notes on
A. Investigations in a case of jaundice
B. Emphysema
C. Familial adenomatous polyposis
D. Inl'ective endocarditis
E. Informed consent
[5 marks each = 25 Marks]

P.T.O
 ?

SECTION -B

V, A42year old lady has a diffuse enlargement of thyroid. She also gives h/o weight gain,
cold intolerance and of feeling very lethargic. Her T3 and T4 levels are reduced and TSH
levels are markedlY increased
A. What is the likelY diagnosis?
B. What is the pathogenesis of this condition?
C. What is the investigation done to confirm this?
D. Gross and microscopic findings in this case.
E. Name 2 malignancies that such patients are at risk to develop.
[1+3+1+3+2 = 1O Marks]
Vi. Write briefly on:
A.3 molecular sub types of Ca breast
8.2 organisms implicated in acute osteomyelitis
c.2 causes for nephrotic sYndrome
D.3 cartilage forming bone tumors
E.3 types of renal cell carcinoma
[2 marks each = 1O Marks]
VIL Write Short notes on:
A. Osteoclastoma
B. Classification of ovarian carcinoma
C. Pathogenesis of complications in diabetes
D. Seminoma
E. Meningioma
[5 marks each = 25 Marks]
\

Hall Ticket No Code No. ECD KFM ttoZ 02 24 1 R

ffivtsHwA vIDYAPErTHAM
SECOND PROFESSIONAL MBBS DEGREE EXAMINATION FEBRUI\RY . 2c24

Time: 3 hrs Max, Marks -1OO

Dater 12lO2/2(J24
PATHOLOGY. PAPER ONE
Instructions: -
; Answer Section A and Section B in separate answer sheets
z Draw labeled diagrams/flow chart wherever necessary.
r Do not write anything on the question paper other than your Hall l-icket No on Top left.

SECTION -A [45 Marks]

I Multiple Choice Questions (Separate question paper and answer sheet attached
[ 1O Marks]

IL Structured Essay:
A. What is hypersensitivity reaction?
B. Mention types of hypersensitivity reaction?
C, Describe pathogenesis of type 2 hypersensitivity reaction giving examples.
L2+4+4 = 1O Marksl
III. Write briefly on:
A. Classify thrombus
B. Give two examples of pathological calcification
C. Special stains for amyloid
D. Give one example each of labile/stable/permanent cells
E. Give names for the following
(a) Benign vascular tumor
(b) Malignant skeletal muscle tumor
(c) Malignant tumour arising from melanocyte
(d) Benign tumour from adipocyte
[2 marks each = 1O Marks]
IV. Write short notes on:
A. Apoptosis
B. Paraneoplastic syndromes
C. Endogenous pigments
D. Define necrosis. Give pathogenesis of coagulative necrosis and give examples
E. Define granuloma. Enumerate the types of granuloma
[5 marks each = 25 Marks]
P.T.O
 SECTION -B [45 Marks]
A 40 year old male with history of alcoholism presented with anemia, loss of appetite,
weakness, numbness and tingling in hands, Hemogram revealed Hb 6 1gldl,l'4CV-
1 06. 9GlFL, M CH -30p9 a nd MCHC- 34o/o, TLC-3, 100/cm m, pl ate et co L ::
I

7 9,000 / cumm. PS-hyperseg mented neutroph i ls

A. What is the diagnosis?

B. Mention the causes
C. Describe the bone marrow picture in this case.
D. Describe the biochemical investigations in this case.
[1+2+3+4 = 10 Marks]
VI. Write briefly on:
A. Causes of microcytic hypochromic a
B. Aplastic anemia causes.
C. Phases of hematopoeisis and thei
D. indications for coombs test
E. What is autologous transfusion?
[2 marks each = 1O Marks]
VII. Write Short notes on:

A. FAB classification of AML

B. CSF picture in TB meningitis
C. Enumerate transfusion transmitted infections
D. Autonomy
E. Enumerate crystals seen in urine
[5 marks each = 25 Marks]
Hall Ticket No. Code No. ECD KFM 7L02 02 24 1. R

ffi vl sHwA vt DYAPE YTYlhhr"

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION FEBRUARY -2024

Time: 1O minutes Max. Marks -1O

Date; 12lO2/2024
PATHOLOGY. PAPER ONE

MULTIPLE CHOICE QUESTIONS (1 mark each)

Instructions: -
', Mark your answers in the answer sheet provided separately

1. Trisomy 21 is the genetic diagnosis of

A. Down syndrome
B, Cri-du-chat syndrome
C. Turner syndrome
D. None of the above
2. All are diseases caused by hemoparasitic protozoa, except:
A. Malaria
B. Babesiosis
C. African sleeping sickness
D. Cryptosporidiasis

3. Lines of Zahn are seen in

A. Thrombosis
B. Red infarct
C. Septic infarct
D. Hyaline degeneration
4. In brown atrophy of heart there is deposition of
A. Melanin pigment
B. Hemosiderin pigment
C. Lipofuschin pigment
D. Ceruloplasmin Pigment

5. Which of the parasites goes to lymphatic system and cause lymphatic obstruction?
A. Hydatid disease
B. Cysticercosis
C. P.vivax
D. Filaria

P,T.O
6. Commonest organ showing extra medullary hematopoiests ts?

A. Lymph nodes
B. Kidney
C. Adrenal
D. Spleen

A. Sodium citrate
B. Double oxalate
C. EDTA potassium
D. Heparin
B. HbF level is increased in?
A. Sickle cell anemia
B. Paroxysmal nocturnal hemoglobinuria
C. Beta thalassemia major
D. Hereditary spherocytosis
A 15 year old boy came to the opd with swe of knee joint after a fall. Family history
revealed that his maternal uncle also similar complaints. His APTT is 65
seconds(control 32 seconds ). Platelets are . The boy is suffering from?

A. Hemophilia A
B. Thrombocytopenic purPUra
C. Von willibrand's disease
D. Hereditary hemorrhagic telangiectasia
10. Hemolytic disease of new born due to ABO incompatibility occurs when?
A. Mother is group A and baby is group O
B. Mother is group B and baby is group O
C. Mother is group O and baby is group A/B
D. Mother is group AB and baby is group O
Hall Ticket No Code No. ECD KFM lIO2 02 24 2 R

iGAAAR-EA
ffi sHwAvl vt DYAPHilTHA/u-

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION FEBRUARY- 2024

Time: 3 hrs Max. Marks -10O

Date: 14lO2/2024
PATHOLOGY. PAPER TWO

Instructions: -
. Answer Section A and Section B in separate answer sheets
; Draw labeled diagrams/flow chart wherever necessary.

SECTION -A [45 Marks]

I Multiple Choice Questions (Separate question paper and answer sheet attached
[ 1O Marks]

IL A. Classify tumors of lung

B. Discuss pathogenesis of bronchogenic carcinoma
C. Discuss gross and microscopic features of squamous cell carcinoma
[3+3+4 = 1O Marks]
IIL Write briefly on:

A. 4 complications of acute Ml

B. Morphologic features of Crohn's disease

C. Types of emphysema
D. Microscopy of psammomatous meningioma
E, 4 causes of liver cirrhosis
[2 marks each = 1O Marks]
IV. Write short notes on:

A. Lab tests of viral hepatitis

B. Glioblastoma multiforme
C. Infective endocarditis
D. Carcinoma stomach
E. Familial Adenomatous Polyposis(FAP)
[5 marks each = 25 Marks]

P.T,O
 SECTION -B [45 Marks]

V.A Defrne meningitis

B Discuss the causative organisms and routes of entry of the various CNS infections
C Compare CSF findings in bacterial meningitis and tubercular meningitts
12+4+4 - 10 Marksl
VI. Write briefly on:

A. Common sites of basal cell carcinoma

B. 4 complications of diabetes mellitus
C. 4 risk factors for carcinoma cervix
D. Benign prostatic hyPerPlasia
E. Hashimotos thyroiditis
[2 marks each = 1O Marks]
VII. Write short notes on:

A. Gross and microscopy of crescentic glomerulonephritis

B. Mention the types of carcinoma breast and their gross appearances
C. Describe pathogenesis and morphologic features of papillary carcinoma thyroid
D. Define osteomyelitis. Enumerate radiologic features, morphology and complications of
chronic osteomyelitis
E. Describe etiopathogenesis and morphology of malignant melanoma of the skin
[5 marks each = 25 Marks]
Hall Ticket No.... Code No. ECD KFM llo2 OZ 24 2 R

ffi v r sHwA v rTlY Alrc-ri-iAlqa

SECOND PROFESSIONAL MBBS DEGREE EXAMINATION FEBRUARY-2024

Time: 1O minutes Max. Marks -1O

Datet 14/02/2024

PATHOLOGY- PAPER TWO

MULTIPLE CHOICE QUESTIONS [I mark each]

Instructions: -
r Write your Hall Ticket Number in this question paper on top left
. Mark your answers in the answer sheet provided separately

1. Sun ray appearance of osteosarcoma is because of?

A. Periosteal reaction
B. Osteonecrosis
C. Calcification along vessels
D. None of the above
2. Large irregular friable vegetations are seen in

A. Rheumatic endocarditis
B. Infective endocarditis
C. Non bacterial thrombotic endocarditis
D. Libman sacks endocarditis
3. Tumor associated with exposure of asbestosis is
A. Mesothelioma
B. Gallbladder cancer
C. Pancreatic cancer
D. Hepatocellular carcinoma
4. Schiller duval bodies are seen in
A. Seminoma
B. Embryonal carcinoma
C. Yolk sac tumour
D. Spermatocytic tumour
5. A 53 year old male comes to emergency room with complaints of chest pain radiating to
left arm and profuse sweating since three hours. ECG showed ST segment elevation.
What is the next most specific lab investigation for confirming the diagnosis?
A. Cardiac troponins
B. LDH
C. Myoglobin
D. ALP
P.T.O
 I
I

6. A 55 year old man presents with increasing fatigue, weakness, anorexia and jaundice
over the past several months Physical examination finds mild ascites and
gynecomastia. A liver biopsy reveals regenerative nodules of hepatocytes surrounded
by fibrosis. What is the best diagnosis for this biopsy specimen?
A. Fatty liver
B. Cirrhosis
C. Cholestasis
D. Hepatitis

7. A 42 year old woman complains of fatigue, irregular menses and hair loss, Total and free
T4 are abnormally low. TSH showed marked elevation, this would be considered wtth:
A. Graves disease
B. Thyrotoxicosis
C. Adenoma of thyroid
D. Primary hyPothyroidism
B. A 75 year old male on colonoscopy showed a constricting mass involving the lower
sigmoid colon. Partial colectomy is advised by the surgeon. Which of the following
techniques used during surgery can best aid the surgeon in determining whether the
resection is adequate to reduce the probability of recurrence?
A. Frozen section
B. Electron microscoPy
C. FNAC
D. Flow cytometry
9. Hlgher incidence of lymphoma is seen in the following condition
A^ Graves disease
B. Hashimoto thyroiditis
C. Nodular goitre
D. Riedels thyroiditis
1"0. Most common benign salivary gland tumor is

A. Plemorphic adenoma
B. Basal cell carcinoma
C. Warthin tumor
D. Lymphoepithelioma
Hall Ticket No... Code No. ECD KFM 7lO2 04 24 7 S

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sEcoND pnoT]SSIONI\L MBBS DEGREE EXAMINATION
APRrL/M AY- 2024 [SUPPLEMENTARY]

Time: 3 hrs Max. Marks -1OO

Dater O5lO5/2()24
PATHOLOGY- PAPER ONE
Instructions: -
; Answer Section A and Section B in separate answer sheets
> Draw labeled diagrams/flow chart wherever necessary.
i Do not write anything on the question paper other than your ilall Ticket No on Top left.

SECTION -A [45 Marks]

I Multiple Choice Questions (Separate question paper and answer sheet attached
[10 Marks]
II. Structured Essay:
A. Define inflammation
B. Describe the cellular events of acute inflammation
C. How does acute inflammation terminate?
D. Enumerate the chemical mediators of acute inflammation
[1+5+2+2 = 1O Marks]
III. Write briefly on:
A. Histological findings in Rhinosporidosis
B. Any 2 complications of wound healing
C. Name any 2 examples of metaplasia
D. Demonstration of amyloid in tussues
E. Any 4 features of Kwashiorkor
[2 marks each = 1O Marks]
IV. Write short notes on:
A. Viral carcinogenesis
B. Type I hypersensitivity reaction
C. Pathological calcification
D. Tuberculoid leprosy
E. Thrombosis
[5 marks each = 25 Marks]
P.T.O
 SECTION -B [45 Marks]
V. A 11 year old boy presented with fever, tiredness, purpuric spots over the bocy a-:
generalized lymphadenopathy. His Hb 6gmo/o: WBC count 1,95,000 cells/cmm: p a:e e:
count 40,000 cells/cmm

A. What is your provisional diagnosis?

B. Describe the lab findings in such a case
C. Mention 2 special stains helpful in the diagnosis
D. List 4 prognostic factors of this condition.
[1+6+1+2 = 1O Marks]
VI. Write briefly on:
A. Any 4 indications for bone marrow study
B. List the crystals seen in acid urine
C. Any 4 causes for eosinophilia
D. Any 2 components of blood and their clinical utility
E. Any 4 conditions of increased ESR

[2 marks each = 1O Marks]

VII. Write Short notes on;

A. Peripheral smear appearance of CML

B. Lab investigations of microcytic hypochromic anemia
C. CSF findings in pyogenic and tuberculous meningitis
D. Hodgkin's disease
E. Transfusion reaction
[5 marks each = 25 Marks]
Hall Ticket No Code No. ECD KFM LL02 04 24 L S

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SECOND PROFESSIONAL MBBS DEGREE EXAMINATION

APRrL/ MAY-2024 [SUPPLEM ENTARY]
Time: 1O minutes Max. Marks -1O
Date: O6lO5/2024
PATHOLOGY- PAPER ONE

MULTIPLE CHOICE QUESTIONS (1 mark each)

Instructions: -
. Write your Hall Ticket Number in this question paper on top left
. Mark your answers in the answer sheet provided separately

1. Caseous necrosis is most characteristic of

A. Cerebral infarct
B. Myocardial infarction
C. Tuberculosis
D. Acute pancreatitis

2. The peripheral smear of a patient shows all features of thalassemia.The investigation

done to establish the diagnosis is
A. ESR estrmation
B. Bone marrow aspiration
C. Blood spherocyte estimation
D. Hb electrophresis
3. Bread and butter appearance is an example of which type of inflammation
A. Catarrhal
B. Fibrinous
C. Purulent
D. Serous
4. "Nutmeg Liver" is seen in:
A. Lrver cirrhosis
B. Liver necrosis
C. Chronic passive congestion
D. Thrombosis of the portal veins

5. Vit deficiency more common in chronic alcoholics is

A. Vit C
B, Thiamine
C. Alpha tocopherol
D. Vit A

P.T.O
6. Early stage of a tumor goes with the following pattern
A. T1 NOMO
B. T4N2M1
C, T2N1MO
D. T3N3M1

7. Parasites seen in blood are all except:

A. Malaria
B. Microfilaria
C. Ascaris
D. Babesiosis

A. Hamartoma
B. Choristoma
C. Teratoma
D. Adenoma
9. The hepatitis viruses not transmitted by parenteral route is

A. Hepatitis B
B. Hepatitis C
C. Hepatitis D
D. Hepatitis A
10. Chronic ITP is characterized by the following except:
A, Splenomegaly
B. Reduced platelet life span
C. Reduced Megakaryocytes in Bone Marrow
D. Anti platelet IgG antibody
 Hall Ticket No........ Code No. ECD KFM l1'OZ 04 24 2 S

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sEcoNDPRoFEssIoNALMBBSDEGREEEXAMINATIoN
APRrL/ MAY- 2024 ISUPPLEMENTARY]
Time: 3 hrs Max. Marks -1OO
Date: O9lO5/2024
PATHOLOGY- PAPER TWO

Instructions: -
, Answer Section A and Sectlon B in separate answer sheets
, Draw labeled diaqrams/flow chart wherever necessary'
left'
r Do not write anything on the question paper other than your Hall Ticket No on Top

SECTION -A [45 Marks]

I Multiple choice Questions (separate question paper and answer sheet attached
[1O Marks]

II A 40 year old man complained of recurrent epigastric pain which aggravated

at night
relieved by food. He had occasional vomiting and bloating of the abdomen

A. What is the Possible diagnosis?

B. Discuss the etioPathogenesis
C, Describe the morPhologY
D. What are the comPlications?
[1+2+5+2 = 1O Marks]
rrr, write briefly on:

A, Any 4 investigations in a suspected case of jaundice

B. Enumerate the different types of emphysema
C. Any 4 organisms causing bacterial endocarditis
D. Any 4 findings in CSF of pyogenic meningitis
E. Any 2 risk factors of lung tumours
[2 marks each = 1O Marks]
IV. Write short notes on:
A. Differentiate Crohn's disease from Ulcerative colitis
B. MorphologY of cirrhosis
C. Cardiac lesions in acute rheumatic fever
D. Lobar pneumonia
E. AutonomY
[5 marks each = 25 Marks]

P.T.O
 SECTION -B [45 Marks]

V. A7 year old boy presented with complaints of fever, reduccd urine output and dark brown(cola
coloured) urine. He gives H/o impetigo lesions on the leg 2 weeks back. Systemic exam-WNL BP
140/90 mmttg, No oedema.
Investigations showed 24 hr urine protein 1gm/day Urine-Alb+, no sugar/ no ketone
microscopy-RBC++,RBC cast+, no bacteria

Blood Urea 60 mg/dl Serum complement-low

A. What is the patient suffering from?

B. What are the nephritogenic strains?
C. What are the light microscopy, immunofluorescence & electron microscopic findings?
D. How do these lesions terminate?
[1+2+5+2 = 1O Marks]
VI. Write briefly on:
A. Write 4 investigations done in a case of diabetes mellitus
B. Gross morphology of serous tumours of ovary
C. Classificatron of infiltrating(invasive)breast carcinoma
D. Any two microscopic features of seminoma testis
E. Any 4 etiological factors of osteosarcoma
[2 marks each = 1O Marks]
ViI. Write short notes on:

A. Renal cell carcinoma

B. Benign prostatic hypertroPhY
C. Benlgn cystic teratoma
D, Complications of diabetes mellitus
E. Basal cell carcinoma
[5 marks each = 25 Marks]
 Hall Ticket No ... Code No. ECD KFM LlO2 04 24 2 S

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SECOND PROFESSIONAL MBBS DEGREE EXAMINATION

APRrL/ M AY -2024[SU PPLE M ENTARY]
Time: 10 minutes Max. Marks -10
Date: O9lO5/2024

PATHOLOGY- PAPER TWO

MULTIPLE CHOICE QUESTIONS [l mark each]

Instructions: -
/'r Write your Hall Ticket Number in this question paper on top teft
Mark your answers in the answer sheet provided separately

1. The lung tumour that can produce cushing's syndrome by elaborating ACTH is
A. Carcinoid
B. Squamous cell carcinoma
C. Adenocarcinoma
D. Small cell carcinoma
2. rn a case of chronic osteomyelitis, a piece of dead bone formed is called
A. Involucrum
B. Sequestrum
C. Brodie abscess
D. Sinus
3. Fine needle aspiration of a thyroid nodule showing intranuclear inclusions, with grooving
and molding of nuclei is suggestive of
A. Follicular adenoma
B. Papillary carcinoma
C. Medullary carcinoma
D. Anaplastic carcinoma

4. Which antibody is not of prognostic significance in cancer breast

A, PR
B. ER
C. Epithelial membrane antigen
D. Her 2 neu
5. Squamous cell carcinoma of cervix is associated with:
A. HPV type 16 & 18
B. Herpes simplex virus
C. HPV type 6 & 11
D. Epstein-Barr virus
P,T,O
6^ The feature that characterizes malignant gastric ulcer from a benign ulcer is
A. Induration of base
B. Heaping uP of margins
C. Fibrous scars radiating from crater
D. All of the above
7. Adenomyosis is the presence of endometrial tissue in:
A. OvarY
B, Uterine wall
C. Pelvic peritoneum
D. Rectovaginal sePtum
B. RBC casts are suggestive of
A. PyelonePhritis
B. Tubular necrosis
C. Acute glomerulonePhritis
D. No significance
9. Friable large destructive vegetations along the valve cusps is due to
A. Rhematic heart disease
B. Libmans sacks endocarditis
C. Non bacterial thrombotic endocarditis
D. Infective endocarditis
10. A 25 year old male presented with a testicular mass^ Serum AFP level was very high.
Microscopy showed cells arranged in anastamosing cords with few Schiller Duval bodies.
The tumour is
A. Seminoma
B. Yolk sac tumour
C. Teratoma
D. Sertoli cell tumour