NAME: DIAGNOSIS: DATE OF ADMISSION: DRUG DATA
GENERIC NAME: Captopril TRADE NAME: Acenorm, Capoten PATIENTS DOSE 25mg tab BID MINIMUM DOSE: 6.25mg PO OD MAXIMUM DOSE: 25mg PO TID CONTENT: captopril AVAILABILITY: Tablets: 12.5mg, 25mg, 50mg, 100mg ROUTE OF ADMINISTRATION: PO PREGNANCY RISK CATEGORY: C; D in 2nd and 3rd trimesters THERAPEUTIC : Antihypertensiv e
AGE: SEX: FEMALE MECHANISM OF ACTION
Inhibits ACE, preventing conversion of angiotensin I to angiotensin II, a present potent vasoconstrictor. Less angiotensin II decreases peripheral arterial resistance, decreasing aldosterone secretion, which reduces sodium and water retention and lowers blood pressure. ONSET: 15-60min PEAK: 60-90min DURATION: 6-12hrs DRUG HALF-LIFE: less than 2hrs PATIENTS ACTUAL INDICATION: Hypertension
HEIGHT: WEIGHT: ADVERSE EFFECTS
CNS: dizziness, fainting, headache, malaise, fatigue, fever CV: tachycardia, hypotension, angina pectoris GI: abdominal pain, anorexia, constipation, diarrhea, dry mouth, nausea, vomiting HEMA: leukopenia, agranulocytosis, thrombocytopenia , pancytopenia METABOLIC: hyperkalemia RESPI: dry, persistent, nonproductive cough, dyspnea SKIN: urticarial rash, pruritus, alopecia
CLASSIFICA TION
PHARMACOL OGIC: ACE inhibitor
INDICATIONS
GENERAL: Hypertension Diabetic Neuropathy Heart failure Left ventricle dysfunction after acute MI
CONTRAINDICATIONS
CONTRAINDICATION: Hypersensitivity to drug or other ACE inhibitors PRECAUTIONS: Use cautiously in pts with impaired renal function or serious autoimmune disease, especially systemic lupus erythematosus, and in those who have been exposed to other drugs that affect WBC counts or immune responses
NURSING RESPONSIBILITIES
BEFORE: Check for doctors order, medication sheet and medication ticket. Determine hypersensitivity reactions. Assess for renal impairment and autoimmune diseases. Take BP. Assess patients knowledge about therapy. Brief patient about the drug. DURING: Observe asepsis. Be alert for adverse reactions. Equipment should be available for any allergic reactions. Withhold if BP is 90/60 and less. Give 1 hour before meals. AFTER: Monitor vital signs and report for any deviation. Instruct pt to report any signs of discomfort experience after therapy. Advise pt to report s/sx of infection. Urge pt to promptly report swelling of the face, lips, or mouth, or difficulty breathing. Encourage for continuity of therapeutic regimen. Document SOURCE: LWW. Nursing Drug Handbook. 2008. p286-288
SOURCE: LWW. Nursing Drug Handbook. 2008. P 286-288
SOURCE: LWW. Nursing Drug Handbook. 2008. p286-288
SOURCE: LWW. Nursing Drug Handbook. 2008. p286-288
SOURCE: LWW. Nursing Drug Handbook. 2008. p286-288
SOURCE: LWW. Nursing Drug Handbook. 2008. p286288
SOURCE: LWW. Nursing Drug Handbook. 2008. p286-288