PATIENT & CAREGIVER EDUCATION
Ginger
 This information describes the common uses of Ginger,
 how it works, and its possible side effects.
    Tell your healthcare providers about any dietary
    supplements you’re taking, such as herbs, vitamins,
    minerals, and natural or home remedies. This will
    help them manage your care and keep you safe.
 What is it?
 Ginger may help relieve or prevent nausea and
 vomiting.
 Ginger root contains compounds that may help relieve or
 prevent nausea and vomiting. These substances can
 increase the flow of saliva and digestive juices and may
 also help calm the stomach and intestines. Some studies
 have found ginger may help nausea caused by
 chemotherapy, but larger studies are needed to confirm
 these effects.
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 Eating fresh ginger in high doses can have blood-
 thinning effects by preventing platelets from sticking
 together. Laboratory studies suggest that ginger can
 protect brain cells from the plaques that cause
 Alzheimer’s disease, but this effect has not been studied
 in humans.
 What are the potential uses and
 benefits?
     To stimulate appetite
     Ginger is known to stimulate saliva flow and digestive
     secretions, but clinical trials are lacking.
     To relieve indigestion
     Compounds in ginger are known to stimulate saliva
     flow and digestive juices, reduce gas, and calm the
     digestive system, but human data are lacking.
     To treat diarrhea
     Compounds in ginger are known to calm the digestive
     system, but clinical data are lacking.
     To treat nausea and vomiting
     Some studies support the short-term use of ginger for
     chemotherapy-associated nausea and vomiting and
     motion sickness. However, ginger supplements should
     not be used around the time of surgery because of
     blood-thinning effects. It is also not suggested for use
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     during pregnancy because of risks to the developing
     embryo.
     To treat arthritis
     A few studies have been conducted with positive
     results, but more research is needed.
     To treat respiratory ailments
     Certain compounds in ginger may reduce
     inflammation and protect against certain viruses, but
     human studies are lacking.
     To treat drug withdrawal symptoms
     A small animal study suggests that ginger may help
     ease withdrawal symptoms from drugs like morphine.
     However, clinical data are lacking.
 What are the side effects?
     Heartburn
     Skin irritation, swelling, and redness
 Case reports
     Nosebleed, slow blood clotting: In a 76-year-old
     woman on long-term blood-thinning therapy who took
     ginger products. Clotting returned to normal after
     discontinuing ginger and with vitamin K
     administration.
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     Severe fatigue and bleeding: In a 65-year-old
     patient who was on multiple medications and also
     took natural products like DHA, blueberry and ginger
     extract supplements, licorice, and pineapple juice.
     Some combination of these were determined to
     contribute to the problem, which was resolved with
     discontinuation of several products while limiting the
     intake of others.
     Fatal bleeding: In an 80-year-old man on a blood
     thinner with a history of irregular heartbeat. He
     presented with 1-day history of vomiting blood and
     black stool that began 3 days after taking a boiled
     mixture of ginger and cinnamon.
 What else do I need to know?
 Patient Warnings:
     Due to its blood-thinning effects, ginger supplements
     should be stopped 2 weeks before surgery, and
     should not be used immediately after surgery to
     control nausea or vomiting.
     Ginger supplements should be avoided in patients
     with bleeding disorders.
     Ginger supplements should be avoided during
     pregnancy or lactation.
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     Ginger supplements should be avoided by individuals
     with gallstones.
 Do Not Take if:
     You are taking warfarin or other blood thinners:
     Ginger supplements may increase the risk of bleeding.
     You are taking NSAIDs, nonsteroidal anti-
     inflammatory drugs: Ginger supplements may
     increase risk of bleeding when used with these drugs.
     You are taking insulin or medication to lower
     blood glucose: Ginger supplements may cause larger
     reductions in glucose levels. Clinical relevance is not
     known.
     You are taking tacrolimus: Ginger supplements
     increase the blood levels of this drug and may
     increase side effects. Clinical relevance is not known.
     You have a bleeding disorder: Ginger supplements
     may increase bleeding time.
     You have gallstones: Ginger supplements may
     increase the flow of bile.
     You are having surgery: Ginger supplements may
     increase risk of bleeding.
     You are pregnant or lactating: The effect of ginger
     supplements on human gestational development are
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     unknown.
    If you have questions or concerns, contact your
    healthcare provider. A member of your care team will
    answer Monday through Friday from 9 a.m. to 5 p.m.
    Outside those hours, you can leave a message or talk
    with another MSK provider. There is always a doctor
    or nurse on call. If you’re not sure how to reach your
    healthcare provider, call 212-639-2000.
 For more resources, visit www.mskcc.org/pe to search
 our virtual library.
 Ginger - Last updated on June 2, 2022
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 Cancer Center
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