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Z Injection 1

The document provides detailed information on various medical injections including Adrenaline, Betnesol, Deriphyllin, Ceftriaxone, Dexona, Gentamicin, and Hepamerz. Each section outlines the drug's uses, mechanisms, dosages, side effects, and contraindications. The document serves as a comprehensive guide for healthcare professionals regarding these medications.

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0% found this document useful (0 votes)
33 views20 pages

Z Injection 1

The document provides detailed information on various medical injections including Adrenaline, Betnesol, Deriphyllin, Ceftriaxone, Dexona, Gentamicin, and Hepamerz. Each section outlines the drug's uses, mechanisms, dosages, side effects, and contraindications. The document serves as a comprehensive guide for healthcare professionals regarding these medications.

Uploaded by

Ruby Khan
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Adrenaline Injection -

Adrenalin (epinephrine injection, USP) 1 mg/mL 1:1000


• Adrenaline injection is one of the most commonly used life-saving drugs.
• It is used to treat various life-threatening conditions such as cardiac arrest and anaphylactic shock.
• Adrenaline injection is also known as epinephrine.
• Epinephrine is a hormone that is released by the adrenal glands.
• Epinephrine or adrenaline is used as a medication because it regulates various body functions.
• It increases blood circulation and increases breathing.

Function of Adrenaline
• Increases blood pressure
• Increases heart rate
• Increases air passage in the lungs
• Distributes blood to muscles
• Regulates carbohydrate metabolism

Treatment
• It is used in various emergency conditions like allergic reactions due to insect bites, food, drugs,
and others.
• It treats severe breathing difficulties.
• It is used when heart function is lost in cardiac arrest.
• It is used when there is a sudden drop in blood pressure.
• It reduces swelling of the face, lips, and throat.

Mechanism
• It stimulates the alpha-1 receptor of smooth muscle.
• This leads to increased smooth muscle contraction, thereby increasing blood pressure.
• It also reduces the effects of histamine, which is responsible for swelling and inflammation.
• It stimulates heart function and rhythm, helping maintain blood flow to the heart.
• It relaxes the muscles of the airways, helping to solve breathing difficulties.

Route of Drug
IM (Intramuscular)
This injection is given intramuscularly when anaphylactic shock develops in the patient.
IV (Intravenous)
It is given intravenously in some other conditions like cardiac arrest.

Side Effects
Anxiety, Tremor, Weakness, Dizziness, Sweating, Nausea, Vomiting, Headache, Yellow skin.

Contraindications (When Not to Use)


Pregnancy
Drug allergy
Liver problems
Kidney problems
Diabetes
Betnesol injection
Betnesol injection is a class of glucocorticoid steroid.
BETAMETHASONE SODIUM
बीटनेसोल इंजेक्शन ग्लूकोकॉर्टिकॉइडस्टेरॉयड क्लास PHOSPHATE INJECTION IP की दवाई होती
है।
This injection contain Betamethasone.
It is used to treat various disease condition in which develop inflammation.

BETNESOL
| 10x8x1ml
gsk
BETAMETHASONE SODIUM PHOSP ECTION IP
BETNESOU
Mechanism
This injection is Corticosteroids so it is show a
anti inflammatory and immunosuppressive action.
It work by inhibit the mediators of inflammation.
It is also invite inflammatory cell and suppress reaction.

Uses
Allergy
Breathing problem
Arthritis
Skin disease
Asthma
Covid 19
• Brain swelling
• Eye pain
• Infection
Uses :-
Hematological disease
Endocrine disorder
Gastrointestinal disease

All allergic condition


Dermatological disease
Nervous system disorder
• Renal disease
Respiratory disease
Dose for Adults

0.75 - 9mg / Day
This injection only use 7 to 10 days.
यहू इंजेक्शन 7 से 10 दिन से ज्यादा इस्तेमाल नहीं करना चाहिए।

Per day 6 mg dose is safe. दिन में 6 mg तक सुरक्षित रहता है.
• It can be used IV or IM
यह शिराओं तथा मांसपेशियों में लगाया जा सकता है।


Side Effects [ दुष्प्रभाव ]
Increase Appetite - भूख बढ़ जाना
Insomnia - नींद ना आना
• Weight gain - वजन का बढ़ जाना
• Vertigo - चक्कर आना

Depression - तनाव
• Hypertension अधिक रक्त दाब
-
Contraindication [ किस मरीज को नहीं देना है 1
• Pregnancy - गर्भावस्था में
• Kidney Disease - किडनी से जुड़ी बीमारियां में
Low thyroid hormones - थाइरॉएडहार्मोस कम होने
पर
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Deriphyllin is a belongs to bronchodilator class drug.
रिफाईलिन इंजेक्शन और टैबलेटब्रॉनकोडाईलेटर क्लास की दवाई
होती है।
Composition
ìci
[
• Etophylline - 84.70mg/ml] Theophylline - fuзituisci 25.30ma / ml ]
Manufactured by: Zydus Healthcare Ltd.
Plot No.1 & 2, First floor, Near Erhardt+Leimer,
Matoda, Ahmedabad-382220.
20
Manufactured at: PF 61 & 62, Sanand GIDC-II Industrial Estate,
Tal.: Sanand, Dist.: Ahmedabad-382110.
Registered Trademark
Injection of Etofylline and Theophylline
DeriphyllinR
Each ml contains:
Theophylline IP anhydrous
2 ml For I.M./I.V.
84.70 mg
Etofylline
eq. to Theophylline IP hydrate
25.30 mg
Excipients
q.s.
Store below 30°C, Protect from light
Dosage: As directed by the Physician
Deriphyllin
Injection of Etophylline and Theophylline 169.4/50.6 mg/2 ml
Deriphylline
Mfg. Lic. No. 965/L
Marketed by
German Remedios
(A division of
Zydus Healthcare Ltd.)
50 x 2 ml Ampoules
Manufactured by: Zydus Healthcare Ltd.
C-6. Flat No. S-1/ST-1, H. No. B-179,
Navelkar Estate. Bainguinim, Old Goa, Tiswadi-Goa
Manufactured at: Plot No. 203-213.
Keep out of reach of children
Discard the injection if any visible particulate matter appears
Mfg. Lic. No.: G/28A/5798-A
O Marketed by: German Remedies
(A division of Zydus Healthcare Ltd.)
Manufactured by: Zydus Healthcare Ltd.
076492
Asthmatic bronchiole
Injection of EtoDeriphyllin
Each mi contains Bolyline Theophylline IP anhydrous
to Theophylline IP hydrate Excipients
Store below 30°C, Protect for Dosage: As directed by the P Keep out of reach of childre M. by
German Reed (A div. of ZydusHealthca My by Zydus Healthcare Plot No.1 & 2 First floor, Near
EaMatoda, Ahmedabad-382220
Normal bronchiole
NORMAL LUNG
ASTHMATIC LUNG
Muscle relaxed
Normal lining
Normal amount
of mucus
AIRWAY
Muscle tightens
Swollen lining
Excess mucus
Use [ इस्तेमाल ]



It is use when blockage in airway. हवा के रास्ते में कोई रूकावट होने पर।
Asthma - अस्थमा होने
Breathing difficulty - सांस लेने में समस्या
• Chronic bronchitis - ब्रोंकाइटिस होने पर

Dose [ कितनी मात्रा में देना है ]
2ml Injection given in medical condition. मेडिकुल की कंडीशन में मरीज को 2 ml इंजेक्शन तुरंत
दिया जाता है.
It can be used IV or IM
यह इंटरेमस्कुलर और इंट्रावेनस दोनों तरीके से दिया जा सकता है।
It can be repeated after 8 hour if needed. यदि जरूरत हो तो 8 घंटे के बाद इसे फिर से दिया जा सकता
है
Side effects high dose [ ज्यादा दवाई के दुष्प्रभाव ]

Headache - सर दर्द

• Trembling in hand - हाथों कप कपि
Nausea vomiting - जी घबराता उल्टी होना
• Cough - खांसी होना
Contraindication [ किस मरीज को नहीं देना है 1]
• Hypokalemia - पोटेशियम कम होने पर

Diabetes - शुगर के मरीज को

Seizures - झटके आने पर
• Hypertension - अधिक रक्तदा होने पर
Irregular heartbeat - हृदय गति काम ज्यादा होने पर
• Coronary artery disease कोरोनरीआर्टरीडिजीज

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Ceftriaxone Injection -
Ceftriaxone Injection IP [Cefritec-500mg ]
Ceftriaxone Injection IP [Cefritec-500mg]
• It is an antibiotic injection that belongs to the cephalosporin class.
• It is a third-generation broad-spectrum antibiotic injection.
• It works by fighting and killing the bacteria.
• It can be used IV (Intravenous) or IM (Intramuscular).

Uses
• Gonorrhea
• Pelvic Inflammation
• Meningitis
• Lung Infection
• Ear Infection
• Skin Infection
• Bone Infection
• Abdominal Infection

Mechanism
• It works as a beta-lactam antibiotic.
• It binds with a specific penicillin-binding site and inhibits the synthesis of the bacterial cell wall.
• Due to this, bacteria stop binary fission and cease growth.

Side Effects
• Nausea
• Bleeding
• Painful urination
• Heartburn
• Chest pain
• Dizziness

Contraindications
• Hemolytic anemia
• Bleeding disorder
• Jaundice
• Drug allergy

Doses
For skin tissue and urinary tract infections:
Normal infection: 1g IV/day
Severe infection: 2g IV/day

For Gonorrheal infection:


250 mg/day (given IM)

For Meningitis infection:


1g BD (twice a day) for 10 days

Children's Dose
75 mg/kg for 2 days
Dexona Injection [ डेक्सोना इंजेक्शन ]
Dexona is a Glucocorticoid steroidal class medicine.
डेक्सोनाग्लूकोकोर्टिकोईडस्टेरॉयड क्लास की दवाई होती है।
In this injection contain Dexamethasone.
इस इंजेक्शन के अंदर डेक्सामेथासोन पाया जाता है।

This injection used to treat inflammation in autoimmune condition.
यह इंजेक्शन इन्फ्लेमेशन तथा ऑटोइम्यून बीमारी में इस्तेमाल की जाती
है।

It is also relief in swelling redness and pain.
यह सूजन आना लाल होना और दर्द में भी आराम करती हैं।
sone Sodium Phospona Injection डेक्सोना
te P equivalent to Phosphate 4 mg
P
ves
P
0.15% w/v 0.02% w/v
re between 15°C
Pected from light
Jed.

Mechanism [ क्रिया ]
This injection is Corticosteroids so it is show a
anti inflammatory and immunosuppressive action. यह इंजेक्शन कॉर्टिकोस्टेरॉइड होता है
इसीलिए यह है एंटीइन्फ्लेमेटरी तथा इम्यूनसिस्टम को सुप्प्रेस करता है।
• It work by inhibit the mediators of inflammation. यह उन तत्वों को भी खत्म करता है जो
इन्फ्लेमेशन के लिए जिम्मेदार है।

It is also invite inflammatory cell and suppress reaction.
यह उन कोशिकाओं को क्रिया करने से रुकती है जो इन्फ्लेमेशन करवाती है।

Uses [ इस्तेमाल 1
Allergy - एलर्जी
Breathing problem - सांस लेने में समस्या Arthritis - अर्थराइटिस
Skin disease - त्वचा रोग
Asthma - 3TFITHT
Covid 19
• Brain swelling सांस लेने में समस्या होना
• Eye pain - आंखों में दर्द
• Infection - किसी भी प्रकार का संक्रमण
Uses [ इस्तेमाल 1

Hematological disease - रक्त संबंधित बीमारियां


Endocrine disorder - एंडोक्राइन से जुड़ी बीमारियां
Gastrointestinal disease - गैस्ट्रोइंटेस्टाइनल बीमारियां
All allergic condition - सभी प्रकार की एलर्जी
·
Dermatological disease - सभी त्वचा संबंधित रोगों में

Nervous system disorder - तंत्रिका तंत्र की बीमारियां
• Renal disease - रिनलडिजीज
·
Respiratory disease - स्वसन संबंधित समस्या
Dose for Adults

0.75 - 9mg / Day
This injection only use 7 to 10 days. यह इंजेक्शन 7 से 10 दिन से ज्यादा इस्तेमाल नहीं करना
चाहिए।
• Per day 6 mg dose Dexamethasone is safe. दिन में 6 mg तक डेक्सोमथासोने का दो सुरक्षित रहता
है.

It can be used IV or IM
यह शिराओं तथा मांसपेशियों में लगाया जा सकता है।
Side Effects [ दुष्प्रभाव 1

Increase Appetite - भूख बढ़ जाना

Insomnia - नींद ना आना
• Weight gain - वजन का बढ़ जाना
• Vertigo - चक्कर आना

Depression - तनाव
• Hypertension - अधिक रक्त दाब
Contraindication [ किस मरीज को नहीं देना है ]
• Pregnancy - गर्भावस्था में
• Kidney Disease किडनी से जुड़ी बीमारियां में


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Gentamicin injection - जेंटामायसीन


GENTAMICIN 80mg/2ml for I.M./slow I.V. use only
● This is an antibiotic that belongs to the aminoglycoside class.
(This injection is an antibiotic that belongs to the aminoglycoside class.)
● Drug: Gentamicin, Strength: 80 mg
● Quantity: 2 ml (80 mg)
● Route: IV and IM
Dose
● 5 mg/kg/day
● It can be used intravenously (IV) or intramuscularly (IM), but if given IV, it should be diluted
and administered over 30 minutes.
(This injection is administered into a vein or muscle, and if given through a vein, it should be
diluted and given over 30 minutes.)
Important
● Gentamicin works systemically.
(Gentamicin works directly in the bloodstream.)
● It has broad-spectrum activity.
(It destroys a wide range of bacteria.)
● It works to kill both gram-positive and gram-negative bacteria.
(It targets both gram-positive and gram-negative bacteria.)
Uses
● Abdominal infections
● Meningitis
● Urinary tract infections
● Respiratory infections
● Blood infections
● Joint infections
Special Uses
● Gentamicin is also used in combination with other antibiotics, like clindamycin, to treat PID
(pelvic inflammatory disease).
(This drug is also given with other antibiotics, like clindamycin, to treat pelvic infections.)
● It is used postoperatively to prevent other infections.
(It is used after surgery to prevent infections.)
● It is effective for abdominal sepsis.
(It helps heal abdominal wounds quickly.)
● It is also effective for ear infections.
Side Effects
● Nausea & Vomiting
● Heartburn
Contraindications (Who should not take it)
● Pregnancy
● Drug allergy
● Renal failure
Note
This injection should not be mixed with any other injection.

Hepamerz Injection
● L-Ornithine-L-Aspartate Infusion (HepaMerz)
● HepaMerz injection belongs to the amino acid class of medicine.
● It contains L-ornithine and L-aspartate, 5 grams.
● L-ornithine and L-aspartate are chemicals made from two amino acids: ornithine and
aspartic acid.
● This injection increases the levels of ornithine and aspartic acid in the body.
● Ornithine and aspartic acid help reduce the level of toxic ammonia in the blood.

Uses
Liver cirrhosis, Hepatic encephalopathy, Jaundice

Failure to Metabolize Ammonia (NH3)


Diseased Liver

Portosystemic Shunt (Blood bypasses liver, reaches general circulation)

Toxins Affect the Brain (Hepatic Encephalopathy)

Hepatic Encephalopathy
Hepatic encephalopathy is also called portosystemic encephalopathy.
This condition occurs when the liver does not filter toxins properly, leading to an increase in toxins in
the blood.
Due to the high level of toxins in the blood, it affects the brain, causing confusion and mental
disorders.
Failure to Metabolize Ammonia (NH3)
Diseased Liver

Portosystemic Shunt (Blood bypasses liver, reaches general circulation)

Toxins Affect the Brain (Hepatic Encephalopathy)

Hepamerz Injection-हेपमेरिज इन्जेक्शन


L-Ornithine-L-Aspartate Infusion (HepaMerz)

• Hepamerz injection is belong to amino acid class medicine.


हेपामेरिज इन्जेक्शन एमीनो एसिड क्लास की मेडिशिन होती है।
• It contain L- ornithine and L-aspartate 5 gram.

• L- ornithine and L-aspartate is a chemical which made two amino acid ornithine and aspartic
acid.
• L- ओर्नीथीन एंड L- एसपारटेट केमिकल होते है जो दो प्रकार के एमीनो एसीड आर्नीथीन तथा
एसपार्टिक एसीड से बना होता है।

• This injection increases the level of ornithine and aspartic acid.


यह इन्जेक्षन शरीर में ओर्नीथीन तथा एसपारर्टीक एसीड की मात्रा को बढ़ाता है।

• This ornithine and aspartic acid help to reduce level toxic chemical ammonia in blood.
यह ओर्नीथीन और एसपारर्टीक एसीड रक्त में टोक्सीन तथा अमोनिया की मात्रा को कम करता
है।
Use
• Liver cirrhosis
• Hepatic encephalopathy - हेपेटी इन्सेपालोपेथी
• Jaundice

Failure to Metabolize NH
Diseased Liver

Portosystemic Shunt (Blood bypasses liver, reaches general circulation)

Toxins Affect the Brain (HE)

Hepatic encephalopathy
• Hepatic encephalopathy also called portosystemic encephalopathy.
हेपेटी इन्सेपालोपेथी को पोरटोसिस्टेमीक इन्सेपेलोपेथी भी कहते है।
• This disease accrues when liver does not filter toxin and increase the level of toxin and blood. यह
बिमारी तब होती है जब हमारा लीवर टोक्सीन को ठीक से फिल्टर नही करता तथा रक्त में
टॉक्सिन कि मात्रा बढ़ जाती है।
• Due to increase level of toxin in blood it effects brain and start Confusion and mental disorder.
टॉक्सिन के रक्त में बढ़ने के कारण मस्तिष्क प्रभावित होने लगता है जिससे की मरीज को
भ्रम तथा मानसिक तनाव व बिमारियाँ होती है।

Failure to Metabolize NH,


Diseased Liver

Portosystemic Shunt (Blood bypasses liver, reaches general circulation)

Toxins Affect the Brain (HE)

Liver cirrhosis

Toxins Affect the Brain (HE)


Healthy liver
Fibrotic liver
Cirrhotic liver
Liver cancer

⮚ Lever cirrhosis is a disease in which healthy liver tissue damage.


लीवर सिरोसिस एक बिमारी होती है जिसमें शरीर के लीवर के टिशु (ऊतक ) टूटने लगते है।

⮚ This disease accrues due to infection or consuming high alcohol.


यह संक्रमण किसी बीमारी या अधिक शराब पिने से होती है।

⮚ When this disease Start liver Tissue repair itself it is called first stage of liver cirrhosis. जब यह
बिमारी चालु होती है तब लीवर के ऊत्तक अपने आप ठीक होने लगते है इसे लीवर
सिरोसिस का प्रथम चरण कहते है।
⮚ At third stage of liver cirrhosis liver tissue completely damage and it does not repair itself. लीवर
सिरोसिस के अंतिम चरण में लीवर के ऊत्तक पूर्ण रूप से टूट जाते है तथा यह अपने
आप ठीक नहीं होते।

⮚ Dilution of injection For dilution of hepamerze injection NS normal saline use.


हेपामर्ज इनजेक्शन को मिलाने के लिए नार्मल सलाइन का इस्तेमाल किया जाता है।

1 ampoules 10ml = 490ml NS = 500ml


INFUSOL NS SODIUM CHLORIDE 0.9% wiv INTRAVENOUS INFUSION BP
INTRAVENOUS UTP NS | 500ml.

Dose
In adult 4 ampoules means 40ml injection can be given to the patient. रोजाना मरीज को 40 ml तक
इन्जेक्शन दिया जाता है।

Note:- This injection should be given in 5 hours very slowly


यह मिलाया गया इन्जेक्षन धीरे-धीरे मरीज को देना है तो भी 8 घंटे में |

Side effect
• Nausea & Vomiting
• Stomach pain

Contraindication - किस मरीज को नहीं देना है।

Life Saving Injection


Mannitol Infusion
This injection reduces pressure in the brain and eyes and also increases urine output.
→Use
● Low intracranial pressure
● Post Operative Eye Surgery
● Post Operative Brain Surgery
Dose:- 100ml in 1 hours
Only use IV

Important
This injection is not used in patients with kidney disease.
→ Side Effects
Headache
Nausea
Vomiting
Chest Pain
Dizzy
Allergy

Isoprenalineinjection
→ Use
2. Complete heart blockage
3. Cardiac Arrest
→ Dose :- 5 mcg / mini
Only use IV

Important
This injection is not used in patients with Tachycardia.
→ Side Effects
Tachycardia
Hypertension
Headache

Vasopressin
→ Use
Maintain Urination
Decrees Urine
→ Dose :- 20 Units / 100ml NS [ 0.03 Unit / minute ]
Use IV injection

Important
This injection is not used in patients with Coronary artery disease.
Side Effects
Abdominal Pain
Chest Pain
Constipation
Beck pain
Coma

Aminophylline injection
This is a bronchodilator drug, which helps to open up the airways.
→ Use :-
● Asthma
● COPD [ Chronic Obstructive Pulmonary Disease ]
● Chronic Bronchitis
Dose :- 0.5mg/Kg - [ 25mg / minute ]
Injection only use IV

Deriphyllineinjection
This is a bronchodilator drug, which helps to open up the airways.
Use
Asthma
COPD [ Chronic Obstructive Pulmonary Disease]
Chronic Bronchitis
Dose :- 110mg - OD [ एक Ampule दिन में एक बार ]
Injection only use IV

Tranexamic Acid injection


This injection helps the blood clot quickly, stopping the bleeding.
Use
● After Surgery
● Caesarean Delivery
● Accidental case
● Piles bleeding
● Nasal bleeding
→ Dose :- 500mg - OD [ दिन में एक बार ]
Injection only use IV
Side Effects :-
Itching
Headache

Calcium Gluconate injection


This injection is used in cardiac arrest because it stimulates the heart muscles to function properly.
Use:
Cardiac Arrest (Heart attack)
Hypocalcemia (Low calcium levels)
Dose:
95 mg - OD (once a day)
This injection is given intravenously (IV) and intramuscularly (IM).

→ Side Effects
Keep out of the reach and sight of children Do not store above 25°C.
Itching
Headache
Nausea
Vomiting
Low BP

Adrenaline (Epinephrine)
This is an enzymatic injection that increases blood flow to muscles. It also acts on the heart's SA
node, helping the heart beat normally.

Use:
Cardiac Arrest (Heart attack)
Anaphylactic Shock
Superficial Bleeding

Side Effects:
Nausea, Vomiting
Dizziness
Swelling

Atropine Injection
This injection inhibits the parasympathetic nervous system.
Use:
Bradycardia (slow heart rate)
Organophosphate poisoning (poisoning from pesticides used in crops)
Side Effects:
Blurred vision
Dizziness
Severe chest pain
Stop Urine retention (difficulty urinating)

Digoxin Injection
Use:
Heart failure (when the heart can't pump blood properly)
If the heart loses its rhythm or stops beating
Dose: IV: 250 mcg
Side Effects:
Nausea
Vomiting
Confusion
Diarrhea
Irregular heartbeat

Nitroglycerin Injection
Nitroglycerin Injection
Use: Hypertension (high blood pressure)
Side Effects:
Nausea and vomiting
Breathing problems
Headache
Dizziness

Hydrocortisone injection
Use:
Allergy reaction
Autoimmune diseases
Side Effects:
Nausea and vomiting
Headache
Chest pain

Dopamine Injection
• Use:
Hypotension
— Side Effects
1. Nausea
2. Vomiting
3. Blur vision
4. Irregular hard beat
Dobutamineinjection
→Use:
Heart Failure (Heart Attack)
This injection quickly stimulates the heart muscles, causing the heart to start beating again.
Side Effects:
Nausea and vomiting
Headache
Chest pain
Breathing difficulty

MONOCEF INJECTION -
Ceftriaxone & Sulbactam for Injection [Monocef - SB 1g ]
Dose and quantity
• monocef - 125mg
• Monocef - 250mg
• Monocef - 500 mg
• Monocef - 1g
• Monocef - 2g
Regular dose = 1-2 g/day
Children dose = 75-100 mg/kg/day

• Monocef is an antibiotic class injection.


• It contains Ceftriaxone.
• It is a popular Cephalosporin antibiotic used for antibacterial purposes.

Important
• This injection is a third-generation Cephalosporin class.
• It works to fight and kill bacteria.
• It can be used IV (intravenously) and IM (intramuscularly).
• It is used to treat different infections caused by bacteria.

Uses
• Lung infection
• Ovary infection
• Ear infection
• Meningitis
• Urinary infection
• Blood infection
• Bone infection
• Joint infection
• Typhoid

Mechanism
• This antibiotic works like a beta-lactam antibiotic.
• Cephalosporin binds with the penicillin binding site and inhibits the synthesis of the bacterial cell
wall.
• Due to this, bacteria are unable to grow and eventually die.

Side Effects
• Bleeding
• Painful urination
• Heartburn
• Nausea and vomiting
• Chest pain
• Stomach pain
• Swelling

Dose and quantity


• Monocef - 125mg , Monocef - 250mg ,Monocef - 500 mg, Monocef - 1g, Monocef - 2g
Regular dose = 1-2 g/day
Children dose = 75-100 mg/kg/day

Adult Dose for Typhoid Fever


First day: 2g in the morning and 2g in the evening
Second day: 1g in the morning and 1g in the evening
Third day: 1g in the morning and 1g in the evening
• Use this dose for three days and check the infection. If needed, increase the dose for 2 more days.

Typhoid Fever in Children


• Dose = 75 mg/kg for 2 days
• Use this dose for 2 days. If the infection is not recovered, increase by one more day.

Contraindications
• Bleeding disorders
• Liver problems
• Gallbladder disease
• Kidney disease
• Newborns

PITOCINE INJECTION -

Pitocin injection contains the oxytocin hormone.


• It is mainly used in many gynecological procedures.
• This injection works to stimulate uterine contractions.

Important
• Oxytocin hormones are released by the pituitary gland during labor.
• This hormone also stimulates milk production in the breast ducts.
Function of Oxytocin
• It helps decrease anxiety.
• It reduces stress and promotes a positive mood.
• It helps with normal childbirth.
• It stimulates proper milk production.
• It is important for reproduction.

PITOCINE INJECTION USE


• It is used during labor for normal delivery.
• It controls bleeding after childbirth.
• It is also used for abortion procedures according to the MTP Act (Medical Termination of
Pregnancy Act, 1971).

Important
• This injection is not used for every delivery.
• It is used when uterine contractions are not occurring properly during labor.

Dose
• This injection is given intravenously by the prescription of a gynecologist or an experienced nurse.
• 1 ml of Pitocin injection is mixed with 1000 ml of Normal Saline to prepare the solution.
• This solution should be given at 0.5 milliliters per minute.
• It can be given at 3-6 ml of dilution per hour.

Side Effects
• Nausea
• Vomiting
• Stomach pain
• Skin allergy

Contraindications (When Not to Use)


• This injection should not be used if the female's first delivery was by C-section.
• It is also not used in cases of malposition (when the baby is not in the normal position).
• It should not be used in patients with high blood pressure.
• It is also not used in cases of twins.

Vomikind injection
Ondansetron Injection IP [VOMIKIND]
● Vomikind injection is an antiemetic class of medicine.
● This medicine contains ondansetron.
● It is a very popular medicine for the treatment of vomiting and nausea.

Important
● It is available in vials and ampules. The vial contains 10ml and the ampule contains 2ml of
medicine.
● In 1ml solution, there is 2mg of ondansetron drug.
● It can be used via IV (intravenous) or IM (intramuscular).

Uses
● Motion sickness
● Nausea & Vomiting
● Morning sickness
● Vomiting in chemotherapy

Mechanism
● In the central nervous system neurons, there are 5-HT3 type serotonin receptors.
● These receptors are responsible for vomiting.
● Ondansetron blocks these receptors, preventing vomiting.

Injection Dilation
● Vomikind injection should be used after dilution.
● NS - Normal saline 5%
● Mannitol 10%
● RL - Ringer's solution
Dose:
● In 1ml injection, 2mg of ondansetron is present.
● 4-8mg (every 8 hours)
● 0.5mg/kg

Side Effects
● Headache
● Dizziness
● Weakness

Contraindications (Who should not receive this medicine):


● Irregular heartbeat
● Chronic liver disease

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