Bio Notes 2 Fatima
Bio Notes 2 Fatima
Contents
Hormones: .............................................................................................................................................. 2
Endocrine disorders: ............................................................................................................................... 3
Theories of Evolution: ............................................................................................................................. 4
   Lamarckism: ........................................................................................................................................ 4
   Darwinism: .......................................................................................................................................... 5
Differences: ............................................................................................................................................. 7
   Differences Between Chemical and Mechanical Digestion ................................................................. 7
   Differences Between Peristalsis and Antiperistalsis............................................................................ 7
   Differences Between Spermatogenesis and Oogenesis ...................................................................... 8
   Differences Between DNA and Chromosomes.................................................................................... 8
   Differences Between Larynx and Pharynx........................................................................................... 9
   Differences Between Growth and Development ................................................................................ 9
   Differences Between RBCs and WBCs ............................................................................................... 10
   Differences Between Arteries and Veins ........................................................................................... 10
   Differences Between Egestion and Excretion ................................................................................... 11
   Differences Between Homozygous and Heterozygous Genes .......................................................... 11
   Differences Between Breathing and Respiration .............................................................................. 11
   Differences Between Aerobic and Anaerobic Respiration ................................................................ 12
Definitions ............................................................................................................................................. 12
Disorders: .............................................................................................................................................. 13
   1. Chronic Bronchitis: ........................................................................................................................ 13
   2. Chronic Obstructive Pulmonary Disease (COPD): ......................................................................... 14
   3. Emphysema: .................................................................................................................................. 14
   4. Lung Cancer:.................................................................................................................................. 14
   5. Atherosclerosis: ............................................................................................................................. 14
   6. Varicose Veins: .............................................................................................................................. 15
               Hormones:
Hormone                              Gland           Target Organ      Function
                                                     Various body
Thyroid hormones (T3 and T4)         Thyroid gland                     Regulates metabolism, growth, and development.
                                                     cells
                                     Pituitary
                                                                       Stimulates milk production in females after
Prolactin                            gland           Mammary glands
                                                                       childbirth.
                                     (Anterior)
                                     Pituitary
                                                                       Stimulates the thyroid gland to produce thyroid
Thyroid-stimulating hormone (TSH)    gland           Thyroid gland
                                                                       hormones (T3 and T4).
                                     (Anterior)
                                     Pituitary       Ovaries
                                                                       In females, stimulates the development of ovarian
Follicle-stimulating hormone (FSH)   gland           (Females), testes
                                                                       follicles. In males, stimulates sperm production.
                                     (Anterior)      (Males)
                                     Pituitary
                                                                       Regulates water balance by promoting water
Antidiuretic hormone (ADH)           gland           Kidneys
                                                                       reabsorption in the kidneys, reducing urine output.
                                     (Posterior)
Hormone                             Gland          Target Organ         Function
                                    Pituitary
                                                   Uterus,        Stimulates uterine contractions during childbirth
Oxytocin                            gland
                                                   mammary glands and milk ejection during breastfeeding.
                                    (Posterior)
                                   Pituitary
                                                   Adrenal glands       Stimulates the adrenal glands to produce cortisol
Adrenocorticotropic hormone (ACTH) gland
                                                   (Cortex)             and other corticosteroids.
                                   (Anterior)
                                    Adrenal
                                                   Various body         Regulate metabolism, immune response, and stress
Corticosteroids                     glands
                                                   tissues              response; include cortisol, aldosterone, and others.
                                    (Cortex)
             Endocrine disorders:
Condition                       Cause                                Key Characteristics/Effects
                                Insufficient production of
                                                                     - Excessive thirst (polydipsia)
                                antidiuretic hormone (ADH) or
Diabetes Insipidus                                                   - Frequent urination (polyuria)
                                resistance to it (due to kidney
                                                                     - Dilute urine, leading to dehydration if not managed
                                dysfunction).
                                    Overproduction of parathyroid
                                                                    - High blood calcium levels (hypercalcemia)
                                    hormone (PTH), usually due to a
Hyperparathyroidism                                                 - Weak bones (osteoporosis), kidney stones
                                    parathyroid adenoma or
                                                                    - Fatigue, muscle weakness, constipation
                                    hyperplasia.
                                    Insufficient production of
                                    parathyroid hormone (PTH), often - Low blood calcium levels (hypocalcaemia)
Hypoparathyroidism                  due to damage to the parathyroid - Muscle cramps, spasms, and numbness
                                    glands during surgery or         - Seizures in severe cases
                                    autoimmune conditions.
            Theories of Evolution:
            Lamarckism:
                  1. Lamarck's Theory: Proposed by Jean-Baptiste Lamarck, it suggested species evolve
                     over time due to environmental changes and internal needs.
                  2. Environmental Influence: Lamarck believed organisms adapt to new needs that arise
                     from environmental changes.
                  3. Use & Disuse: Traits or organs that are frequently used become stronger, while
                     unused organs atrophy.
                  4. Inheritance of Acquired Characteristics: Traits acquired during an organism's
                     lifetime are passed down to offspring.
                  5. Speciation: Over time, new species could arise from existing ones due to
                     accumulated changes.
                  6. New Needs: Organisms develop new traits to meet evolving environmental demands.
   7. Example of Giraffes: Lamarck suggested giraffes developed long necks because
      ancestors stretched their necks to reach tall trees.
   8. Inheritance Mechanism: Lamarck proposed that acquired traits (e.g., longer necks)
      were inherited by offspring.
   9. Criticism 1 – Lack of Evidence: No experimental proof that acquired traits are
      passed to offspring.
   10. Criticism 2 – Contradicts Genetics: Lamarckism conflicts with Mendelian genetics,
       which shows traits are inherited via genes.
   11. Criticism 3 – Lack of Mechanism: Lamarck couldn't explain how acquired traits
       were inherited biologically.
   12. Criticism 4 – Acquired Traits Aren’t Inherited: Modern genetics disproved the
       inheritance of traits acquired through use or disuse.
   13. Lamarck’s Mistakes – Inheritance of Acquired Traits: Belief that traits acquired
       during life could be passed to offspring was incorrect.
   14. Lamarck’s Mistakes – Overemphasis on Environment: Focused too much on the
       environment, neglecting the role of genetic variation and natural selection.
   15. Lamarck’s Mistakes – No Genetic Knowledge: His theory lacked the understanding
       of DNA and gene-based inheritance.
   16. Significance 1 – Early Contribution: Lamarck was one of the first to propose
       evolution as a process of change over time.
   17. Significance 2 – Adaptation: Emphasized the role of adaptation to the environment,
       influencing later evolutionary theories.
   18. Significance 3 – Organism-Environment Interaction: Highlighted how organisms
       interact with their environment, foreshadowing ecological studies.
   19. Significance 4 – Stimulating Research: Lamarck’s ideas spurred further research,
       leading to Darwin's natural selection theory and the modern synthesis of evolution.
   20. Legacy: Although flawed, Lamarck’s theory helped lay the groundwork for future
       evolutionary theories.
Darwinism:
   1. Darwinism: A theory of evolution proposed by Charles Darwin, explaining how
      species evolve through natural selection.
   2. H.M.S. Beagle Voyage (1831-1836): Darwin’s five-year voyage around the world
      aboard the Beagle significantly influenced his evolutionary ideas.
   3. Observations on the Beagle: Darwin observed distinct species across different
      islands, especially in the Galápagos, which led to his insights on adaptation and
      evolution.
   4. Fossils: Darwin found fossils of extinct species that resembled living species,
      suggesting species could change over time.
5. Endemic Species: Darwin observed unique species on isolated islands, helping him
   understand how adaptation to specific environments works.
6. Charles Darwin: Born in 1809, Darwin was an English naturalist who developed the
   theory of evolution by natural selection.
7. "On the Origin of Species" (1859): Darwin’s landmark book that laid out his theory
   of evolution, including the mechanism of natural selection.
8. Natural Selection: Darwin proposed that individuals with advantageous traits survive
   and reproduce, passing those traits to the next generation.
9. Overproduction: Organisms produce more offspring than the environment can
   support, leading to competition for resources.
10. Competition: Since resources are limited, individuals compete for food, mates, and
    shelter, affecting their survival and reproduction.
11. Genetic Variation: Within populations, there is variation in traits, which can affect
    the survival and reproductive success of individuals.
12. Adaptation: Traits that improve survival or reproduction in a given environment
    become more common in the population over generations.
13. Natural Selection in Action: Organisms with beneficial traits are more likely to
    survive and reproduce, leading to the accumulation of those traits in future
    generations.
14. "Survival of the Fittest": The phrase emphasizes that the most well-adapted
    individuals are the ones most likely to survive and reproduce.
15. Speciation: Over time, accumulated changes lead to the formation of new species,
    particularly when populations become isolated and cannot interbreed.
16. Geographic Isolation: When populations are geographically separated, they evolve
    differently, leading to the formation of distinct species.
17. Reproductive Isolation: As differences accumulate, isolated populations may no
    longer interbreed, resulting in the emergence of new species.
18. Significance 1 – Unifying Biology: Darwin's theory unified the study of biology by
    explaining the diversity of life through evolution.
19. Significance 2 – Modern Evolutionary Theory: Darwinism laid the foundation for
    the Modern Synthesis, which integrates genetics into the theory of evolution.
20. Significance 3 – Genetic Impact: Darwin’s work inspired research into genetics,
    leading to a deeper understanding of inheritance and variation.
21. Significance 4 – Natural Selection: Darwin highlighted natural selection as the key
    mechanism for evolutionary change, influencing countless studies in biology.
22. Significance 5 – Common Ancestry: Darwin’s theory provided evidence for the idea
    that all living organisms share a common ancestry.
23. Criticism 1 – Lack of Genetic Mechanism: At the time, Darwin could not explain
    how traits were inherited, as genetics were not understood yet.
   24. Criticism 2 – Fossil Gaps: Critics argued that the fossil record was incomplete, with
       missing transitional forms between species.
   25. Criticism 3 – Rate of Evolution: Some felt that gradual evolution couldn’t account
       for the rapid appearance of new species, leading to debates on the pace of evolution.
Differences:
Differences Between Chemical and Mechanical Digestion
 1. Chemical Digestion:
        o       Definition: The process by which enzymes break down food into simpler
                molecules (e.g., proteins into amino acids, carbohydrates into sugars).
        o       Location: Occurs mainly in the stomach and small intestine.
        o       Involves: Enzymes (e.g., amylase, pepsin, lipase) and digestive juices.
        o       Purpose: Breaks down complex food molecules into absorbable nutrients.
        o       Example: The breakdown of starch into glucose by amylase.
 2. Mechanical Digestion:
        o       Definition: The physical breakdown of food into smaller pieces without
                changing its chemical structure.
        o       Location: Occurs in the mouth (chewing) and stomach (churning).
        o       Involves: Teeth, tongue, and stomach muscles.
        o       Purpose: Increases the surface area of food to enhance the efficiency of
                chemical digestion.
        o       Example: Chewing of food to break it down into smaller pieces.
Definitions
   1. Hormones: Chemical signals produced by glands that control body functions like
      growth, metabolism, and mood.
   2. Hypothalamus: A brain part that controls hunger, temperature, and releases hormones
      to manage other glands.
   3. Pituitary Gland: A small gland in the brain that controls important processes like
      growth and reproduction through hormone release.
   4. Endocrine Theory: The idea that hormones, released by glands, regulate various
      body functions.
   5. Hypothesis: A testable prediction or explanation based on observations and existing
      knowledge.
   6. Fossils: Preserved remains or traces of ancient life, showing how species have
      evolved over time.
   7. Genotype: The genetic makeup of an organism, the set of genes inherited from its
      parents.
   8. Phenotype: The physical traits or characteristics of an organism, such as eye colour
      or height.
   9. Allele: Different versions of a gene that can influence traits, like blue or brown eyes.
   10. Genes: Segments of DNA that provide instructions for making proteins and
       determining traits.
   11. Mutation: A change in the DNA sequence that can lead to new traits or genetic
       diversity.
   12. Karyotype: The complete set of chromosomes in an organism, used to study genetic
       material.
   13. Phenotypic Plasticity: The ability of an organism to change its traits in response to
       environmental factors.
   14. Structure of Genes: Genes are made of DNA, which consists of sequences of
       nucleotides encoding proteins.
   15. Genetics: The study of how traits are inherited from parents to offspring through
       genes.
   16. Species: A group of organisms that can interbreed and produce fertile offspring.
   17. Population: A group of the same species living and interacting in a specific area.
   18. Mendel’s Laws: Principles of inheritance discovered by Gregor Mendel that explain
       how traits are passed to offspring.
   19. Law of Segregation: The rule that each individual has two alleles for each trait, and
       these alleles separate during reproduction.
   20. Law of Independent Assortment: The principle that genes for different traits are
       inherited independently of each other.
Disorders:
1. Chronic Bronchitis:
   •   Definition: Chronic inflammation of the bronchial tubes, which causes a persistent cough
       and mucus production.
   •   Causes: Smoking is the most common cause; long-term exposure to irritants like pollution or
       dust can also contribute.
3. Emphysema:
   •   Definition: A type of COPD where the air sacs (alveoli) in the lungs are damaged, leading to
       difficulty in exhaling air and reduced oxygen intake.
   •   Causes: Long-term smoking is the primary cause; exposure to pollutants and genetic factors
       (e.g., alpha-1 antitrypsin deficiency) can also contribute.
• Complications: Respiratory failure, heart problems, and increased risk of lung infections.
4. Lung Cancer:
   •   Definition: A type of cancer that starts in the lungs, often due to abnormal cell growth.
   •   Symptoms: Persistent cough, chest pain, shortness of breath, coughing up blood, weight
       loss, fatigue.
   •   Causes: Smoking is the leading cause, though environmental factors (radon exposure,
       second-hand smoke, air pollution) and genetic factors can also contribute.
5. Atherosclerosis:
   •   Definition: A condition where plaque (fatty deposits) builds up inside the arteries, narrowing
       and hardening them, restricting blood flow.
   •   Symptoms: Often no symptoms in early stages, but can lead to chest pain, stroke, heart
       attack, or peripheral artery disease.
   •   Causes: Poor diet (high in fats and cholesterol), lack of exercise, smoking, high blood
       pressure, diabetes, and genetic factors.
6. Varicose Veins:
   •   Definition: Swollen, twisted veins, usually in the legs, caused by weakened or damaged
       valves in the veins that allow blood to flow backward.
• Symptoms: Visible, bulging veins, aching, swelling, cramps, and heaviness in the legs.
• Causes: Age, pregnancy, obesity, prolonged standing, family history, and hormonal changes.