DPP - Daily Practice Problems
Chapter-wise Sheets
Date :                             Start Time :                                   End Time :
                                                                                                        CB09
                                                 SYLLABUS : Biomolecules
Max. Marks : 180               Marking Scheme : + 4 for correct & (–1) for incorrect                            Time : 60 min.
     INSTRUCTIONS : This Daily Practice Problem Sheet contains 45 MCQs. For each question only one option is correct.
     Darken the correct circle/ bubble in the Response Grid provided on each page.
1.    A nucleotide is formed of                                5.    In RNA, thymine is replaced by
      (a) Purine, pyrimidine and phosphate                           (a) Adenine                   (b) Guanine
      (b) Purine, sugar and phosphate                                (c) Cytosine                  (d) Uracil
      (c) Nitrogen base, sugar and phosphate                   6.    Which of the following is a reducing sugar?
      (d) Pyrimidine, sugar and phosphate                            (a) Galactose                 (b) Gluconic acid
2.    Glycogen is a polymer of                                       (c) -methyl galactoside (d) Sucrose
      (a) galactose                 (b) glucose                7.    An enzyme that can stimulate germination of barley seeds
      (c) fructose                  (d) sucrose                      is
3.    Most abundant organic compound on earth is                     (a) lipase                    (b) protease
      (a) Protein                   (b) Cellulose                    (c) invertase                 (d) -amylase
      (c) Lipids                    (d) Steroids               8.    Carrier ions like Na+ facilitate the absorption of substances
4.    Protein synthesis in a cell takes place                        like:
      (a) only in the cytoplasm                                      (a) amino acids and glucose
      (b) in the nucleolus as well as in cytoplasm                   (b) glucose and fatty acids
      (c) in cytoplasm as well as in mitochondria                    (c) fatty acids and glycerol
      (d) only on ribosomes attached to the nuclear envelope         (d) fructose and some amino acids
      RESPONSE          1.                  2.                  3.                   4.                    5.
        GRID            6.                  7.                  8.
                                                    Space for Rough Work
 B-34                                                                                                           DPP/ CB09
9.    An enzyme brings about                                       15.   Sigmoid growth curve is represented by
      (a) decrease in reaction time                                      (a) dN/dt = rN
      (b) increase in reaction time                                      (b) dN/dt = rN (1 – N/K)
      (c) increase in activation energy                                  (c) Nt = No + B + I – D – E
      (d) reduction in activation energy                                 (d) dN/dt = 1 – N/K
10.   The enzymes hexokinase which catalyses glucose to            16.   A coenzyme is
      glucose-6-phosphate in glycolysis is inhibited by glucose-         (a) Same enzyme that occurs in different tissues such as
      6-phosphate. This is an example of                                      heart and muscle
      (a) competitive inhibition                                         (b) One that shares the function of other enzyme
      (b) non-competitive inhibition                                     (c) Organic or inorganic in nature and helps activate
                                                                              metabolic enzymes
      (c) feedback allosteric inhibition
                                                                         (d) Organic non-protein in nature and helps to activate
      (d) positive feedback
                                                                              metabolic enzymes
11.   The enormous diversity of protein molecules is due mainly
                                                                   17.   The most basic amino acid is
      to the diversity of
                                                                         (a) Arginine             (b) Histidine
      (a) amino groups on the amino acids
                                                                         (c) Glycine              (d) Glutamine
      (b) R groups on the amino acids
                                                                   18.   Which of the following is not an aromatic amino acid?
      (c) amino acid sequences within the protein molecule
                                                                         (a) Valine               (b) Tyrosine
      (d) peptide bonds
                                                                         (c) Phenylalanine        (d) Tryptophan
12.   Length of one turn of the helix in a B-form DNA is
      approximately                                                19.   The class of enzymes that catalyze the removal of a group
                                                                         from a substrate without addition of water, leaving double
      (a) 3.4 nm                   (b) 2 nm
                                                                         bonds, is
      (c) 0.34 nm                  (d) 20 nm
                                                                         (a) Transferases         (b) Dehydrogenases
13.   The catalytic efficiency of two different enzymes can be
                                                                         (c) Hydrolases           (d) Lyases
      compared by the
                                                                   20.   Which of the following is a component of vitamin (thiamine,
      (a) formation of the product                                       biotin), Acetyl CoA, cysteine, methionine and ferredoxin?
      (b) pH optimum value                                               (a) Fe                   (b) S
      (c) Km value                                                       (c) Co                   (d) K
      (d) molecular size of the enzyme                             21.   The helical structure of protein is stabilized by
14.   Which of the following sets contains polysaccharides?              (a) Ester                (b) Peptide bonds
      (a) Glucose, fructose, lactose                                     (c) Disulphide bonds (d) Hydrogen bonds
      (b) Starch, glycogen, cellulose                              22.   Cellulose is a polymer of
      (c) Sucrose, maltose, cellulose                                    (a)    -glucose               (b) -D-glucose
      (d) Galactose, starch, sucrose                                     (c) -D-glucose                (d) -L-glucose
                        9.                   10.                   11.                  12.                   13.
      RESPONSE
                        14.                  15.                   16.                  17.                   18.
        GRID
                        19.                  20.                   21.                  22.
                                                      Space for Rough Work
DPP/ CB09                                                                                                                      B-35
23. The given graph shows the effect of substrate concentration         Given structural formula is correctly identified alongwith its
    on the rate of reaction of the enzyme green -gram -                 related function by which of the following options?
    phosphatase. What does the graph indicate ?                         (a) Cholesterol – A component of animal cell membrane
                                                                        (b) Lecithin – A component of cell membrane
                                                                        (c) Triglyceride – An energy source
                                                                        (d) Adenosine – A component of nucleic acids
                                                                  27.   Select the option that correctly identifies the chemical bonds
                                                                        present in the given biomolecules.
                                                                        Polysaccharides – A, Proteins – B, Fats – C, Water – D
                                                                                  A            B           C             D
                                                                        (a) Ester          Peptide Glycosidic          Hydrogen
                                                                        (b) Glycosidic Peptide Ester                   Hydrogen
    (a) The rate of enzyme reaction is directly proportional to         (c) Glycosidic Peptide Hydrogen                Ester
        the substrate concentration                                     (d) Hydrogen Ester             Peptide         Glycosidic
    (b) Presence of an enzyme inhibitor in the reaction mixture   28.   Which of the following statements is not correct regarding
    (c) Formation of an enzyme-substrate complex                        chitin?
    (d) At higher substrate-concentration the pH increases.             (a) It is a storage polysaccharide
24. The Km value of the enzyme is the value of the substrate            (b) It is a homopolysccharide
    concentration at which the reaction reaches to                      (c) It is a constituent of arthropod exoskeleton and fungal
    (a) Zero                   (b) 2 Vmax                                    cell wall
    (c) ½ Vmax                 (d) ¼ Vmax                               (d) It is the second most abundant carbohydrate on earth
25. Which group contains biocatalysts?                            29.   Which of the following secondary metabolites are used as
                                                                        drugs?
    (a) Myosin, oxytocin, adrenalin                                     (a) Abrin and ricin
    (b) Peptidase, amylase, rennin                                      (b) Vinblastin and curcumin
    (c) Glucose, amino acids, fatty acids                               (c) Anthocyanins
                                                                        (d) Gums and cellulose
    (d) Rhodopsin, pepsin, steapsin
                                                                  30.   Enzymes that catalyse removal of groups from substrates
26.
                                                                        by mechanisms other than hydrolysis, and addition of
                                 O
                                                                        groups to double bonds, are called
          O           CH2     O   C    R1                               (a) ligases              (b) lyases
                                                                        (c) hydrolases           (d) dehydrogenases
    R2    C     O     CH          O                               31.   Which of the following statement is incorrect w.r.t. starch?
                                                                        (a) Starch consists of unbranched amylose and branched
                      CH2     O   P    O    CH2 CH2                          amylopectin
                                                                        (b) It is a polymer of -D-glucose
                                  OH                N+
                                                                        (c) Successive glucose units are linked together by 1
                                              CH3     CH                     6 linkage and at branching 1 4 linkage is found
                                                    CH3 3
                                                                        (d) Starch turns black with iodine
     RESPONSE           23.                  24.                  25.                    26.                   27.
       GRID             28.                  29.                  30.                    31.
                                                      Space for Rough Work
 B-36                                                                                                          DPP/ CB09
32.   Cellulose differs from chitin in                            40. The structure of glucose and galactose are same except
      (a) Branching                                                   with regard to
      (b) Type of glycosidic bond                                     (a) First carbon atom
      (c) Type of monomer unit                                        (b) Second carbon atom
      (d) Abundancy in biosphere                                      (c) Third carbon atom
33.   Oils are rich in                                                (d) Fourth carbon atom
                                                                  41. All the following statements are true with regard to glucose,
      (a) Glycerol that possesses three hydroxyl groups               except :
      (b) Saturated fatty acids                                       (a) It is an aldohexose
      (c) Fats that are generally liquid at room temperature          (b) It is a reducing sugar
      (d) Esters of fatty acids                                       (c) It is present in starch and cellulose
34.   Bonds that do not exist in tertiary structure of proteins       (d) It is an epimer of fructose
      (a) Covalent bonds                                          42. Guanylic acid is a
      (b) Phosphodiester bonds                                        (a) Nucleoside of purine
      (c) Hydrophobic etnractions                                     (b) Nucleoside of pyrimidine
      (d) Ionic bonds                                                 (c) Nucleotide of purine
35.   Cleavage of specific covalent bonds and removal of groups       (d) Nucleotide of pyrimidine
      without hydrolysis is the property of                       43. Long chain molecules of fatty acids are formed by
      (a) Isomerases           (b) Lyases                             (a) Polymerisation of 2 carbon compounds
      (c) Hydrolases           (d) Transferases                       (b) Decomposition of fats
36.   The catalytic efficiency of two different enzymes can be        (c) Polymerisation of glycogen
      compared by the                                                 (d) Conversion of glycogen
      (a) Km value                                                44. Read the following four statements (A to D) and mark the
      (b) pH value                                                    option that has both correct statements
      (c) Formation of the product                                    A. Blood conc. of glucose in a normal healthy man is 4.5
      (d) Molecular size of the enzyme                                      to 5.0 mM
37.   Which of the following is an example of isozyme?                B. In proteins only left handed helices are observed
      (a)    -Amylase                                                 C. The pitch of B- DNA is 3.4 Angstrom
      (b) Glucokinase                                                 D. At each step of ascent the strand of DNA turns 36
      (c) Lactate dehydrogenase                                             degree
      (d) All of these                                                (a) A, B        (b) B, C        (c) C, D      (d) A, D
38.   Essential amino acids include                               45. Which one of the following biomolecules is correctly
      (a) leucine              (b) valine                             characterized?
      (c) tryptophan           (d) all of these                       (a) Lecithin - A phosphorylated glyceride found in cell
39.   Acidic amino acids have two –COOH groups and one –                    membrane.
      NH2 group per molecule. Select the pair that consists of        (b) Palmitic acid - An unsaturated fatty acid with 18 carbon
      acidic amino acids.                                                   atoms.
      (a) Aspartic acid, glutamic acid                                (c) Adenylic acid - Adenosine with a glucose phosphate
      (b) Lysine, arginine                                                  molecule.
      (c) Glycine, alanine                                            (d) Alanine amino acid - Contains an amino group and an
      (d) Both (a) and (b)                                                  acidic group anywhere in the molecule.
                        32.                  33.                  34.                  35.                   36.
      RESPONSE
                        37.                  38.                  39.                  40.                   41.
        GRID
                        42.                  43.                  44.                  45.
                                                      Space for Rough Work
         DAILY PRACTICE PROBLEM DPP CHAPTERWISE 9 - BIOLOGY
      Total Questions         45      Total Marks                 180
      Attempted                       Correct
      Incorrect                       Net Score
      Cut-off Score           45      Qualifying Score            55
            Success Gap = Net Score – Qualifying Score
                      Net Score = (Correct × 4) – (Incorrect × 1)
                                         HINTS & SOLUTIONS
                            DPP /CB09
                                                                              12.    (a)   Length of one turn of DNA helix is 34Å.
1.    (c)   The nucleic acid (DNA and RNA) are repeating units of                          1Å = 10–1 nm
            nucleotides i.e. polynucleotides. Each nucleotide comprises       13.    (c)   Km (Michealis Menten constant) is defined as that substrate
            of nitrogenous heterocyclic bases viz. purines or pyrimidines,                 concentration at which under optimum conditions the rate of
            pentose sugar and phosphoric acid.                                             an enzyme catalysed reaction reaches half the maximum rate.
2.    (b)   Glycogen is an animal starch, stored in the liver and is                       Km is inversely proportional to affinity of enzyme for its
            polysaccharide of          Glucose. About 30,000 glucose                       substrate.
            molecules joined by 1-4          -glycosidic bonds and its        14.    (b)      15. (a)       16. (d)         17. (a)       18. (a)
            branches by 1-6 glycosidic bonds. It gives red colour with        19.    (d)      20. (b)       21. (d)         22. (c)       23. (b)
            iodine solution.                                                  24.    (c)      25. (b)
            • Galactose is a monosaccharide from milk.                        26.    (b)   Phospholipids are triglyceride lipids, in which one fatty acid
            • Fructose is a monosaccharide from fruit.                                     is replaced by phosphoric acid residue often linked to
            • Sucrose is a disaccharide (Glucose + Fructose).                              additional nitrogenous groups like choline (in lecithin),
3.    (b)   Cellulose is the most abundant organic compound, most                          ethanolamine (in cephalin) etc.
            abundant polysaccharide and most abundant biopolymer
                                                                                             CH2      O         CO       R1
            found on earth.
4.    (c)   In the cytoplasm, protein synthesis is restricted to the                        CH                 CO       R2
                                                                                                     O
            ribosomes. Mitochondria being a semiautonomous organelle,
            has its own genetic machinery to synthesize its proteins.                                          O
                                                                                                                                   +
5.    (d)   RNA is a single chain of ribonucleotides. Each ribonucleotide                   CH2      O         P       (CH2)2     N(CH3)3
            consists of nitrogenous bases (adenine, guanine, cytosine
                                                                                                               O              Choline
            and uracil), ribose sugar and phosphoric acid.
                                                                                                           Phosphate
6.    (a)   Reducing sugar is any sugar that has an aldehyde group or is                           Fig. : Structure of lecithin.
            capable of forming one in solution through isomerisation.
            Reducing monosaccharides include glucose, fructose,               27.    (b)   Polysaccharides, monosaccharides are linked together by
            glyceraldehyde and galactose. Many disaccharides, like                         glycosidic bond (C–O–C). Water has hydrogen bonding.
            lactose and maltose also have a reducing form, as one of the                   Proteins and polymers of different amino acids, which are
            two units may have an open- chain form with an aldehyde                        linked by peptide (CONH) bond formed by dehydration
            group.                                                                         (polymerisation) between COOH group of one amino acid
            However, sucrose and trihalose in which the anomeric carbons                   and NH2 group of next amino acid with the removal of H2O.
            of the two units are linked together, are non reducing                         The three hydroxyl groups of a glycerol molecule join with
            disaccharides since neither of the rings is capable of opening.                the the carboxyl groups of three fatty acid molecules to form
7.    (d)     -amylase enzyme stimulates the germination of barley                         a fat or triglyceride molecule. The chemical linkage between
            seed.                                                                          the glycerol and fatty acids is called the ester bond.
8.    (a)   Massive ions like Na+ facilitate the absorption of substances     28.    (a)   Chitin is the second most abundant polysaccharide (after
            like amino acid and glucose through cotransport.                               cellulose). Chitin is not a storage polysaccharide rather it is a
9.    (d)   Enzymes accelerate chemical reaction by lowering the                           structural homopolysaccharide, formed of N-
            activation energy.                                                             acetylglucosamine (NAG) monomers joined together by -
10.   (c)   Competitive inhibition is the reversible inhibition of enzyme                  1, 4 linkages. Also, it forms the structural component of
            activity due to presence of substrate analogues. Non                           fungal walls and exoskeleton of arthropods.
            competitive inhibition is the reduction of enzyme activity        29.    (b)
            by a factor that has no real structural similarity with the
            substrate. Allosteric inhibition is reversible non-                                    Some Secondary Metabolites
            competitive inhibition occurring in case of allosteric                  Pigments               Carotenoids, anthocyanins, etc.
            enzymes . Herein, the inhibitors are the products or                    Alkaloids              Morphine, Codeine, etc.
            intermediates of reactions catalyzed by the enzymes.
            Hence, it is also called end product inhibition or feedback             Terpenoids             Monoterpenes, Diterpenes, etc.
            inhibition.                                                             Essential oils         Lemon grass oil, etc.
11.   (c)   There are only 20 amino acids . These can be arranged in                Toxins                 Abrin, Ricin
            different order in the polypeptide chain to form a diverse              Lectins                Concanavalin A
            array of proteins.
                                                                                    Drugs                  Vinblastin, Curcumin, etc.
                                                                                    Polymeric substances Rubber, Gums, Cellulose.
                                                                                     Vinblastin is used as an anticancer drug, whereas curcumin is a
                                                                                     component of turmeric and also used as drug.
30.   (b)   Lyases enzyme catalyze the breakage of specific covalent
            bonds and removal of groups without hydrolysis producing
            double bonds or removal of double bonds by adding groups
            e.g., histidine decarboxylase that splits C–C bond of histidine,
            forming CO2 and histamine.
            X     Y
            |     |
                      lyase
            C— C               X—Y C C
      Fructose-1, 6 diphosphate         Aldolase     Dihydroxyacetone-3-
            phosphate + Glyceraldehyde-3-phosphate.
31.   (c)   Successive glucose units are linked together by 1        4
            linkage and at branchings 1       6 linkage is present.
32.   (c)           33.      (c)
34.   (b)   Tertiary structure of proteius is devoid of phosphodiester
            bonds. There bonds are present in nudeic acids.
35.   (b)
36.   (a)   A high k m indicates low affinity of an enzyme for its
            substrate.
37.   (d)   The multiple molecular forms of an enzyme occuring in the
            same organisms and having a similar substrate activity are
            called isoenzymes or isozymes. They have similar properties
            but different molecular weights and location. Over 100
            enzymes are known to have isoenzymes. -amylase of wheat
            endosperm has 16 isozymes, lactate dehydrogenase has 5
            isozymes.
38.   (d)   Essential amino acids are the amino acids which cannot be
            synthesized by organisms in the body and are obtained from
            plants e.g., valine, leucine, isoleucine, phenylalanine, threonin,
            lysine, tryptophan, methionine.
            Non-essential amino acids can be synthesized by the organism
            and may not be the requisite components of diet e.g., serine,
            tryosine, aspartate, cysteine, glutamate, proline, glycrine,
            alanine, asparagine, glutamine and tyrosine.
39.   (a)   Acidic amino acids have an extra carboxylic group (mono-
            amino dicarboxylic), e.g., glutamate (glutamic acid, Glu),
            asparate (aspartic acid, Asp).
            Basic amino acids have an additional amino group without
            forming amides (diamino monocarboxylic), e.g., arginine
            (Arg), lysine (Lys).
            Neutral amino acids have one amino group and one carboxylic
            group (mono-amino mnocarboxylic) with noncyclic
            hydrocarbon chain, e.g., glycine (Gly), alanine (Ala), valine
            (Val), Leucine (Leu), isoleucine (lle). Essential amino acids
            are the amino acids which cannot be synthesized by organisms
            in the body and are obtained from plants e.g., valine, leucine,
            isoleucine, phenylalanine, threonin, lysine, tryptophan,
            methionine.
            Non-essential amino acids can be synthesized by the organism
            and may not be the requisite components of diet e.g., serine,
            tryosine, aspartate, cysteine, glutamate, proline, glycrine,
            alanine, asparagine, glutamine and tyrosine.
40.   (d)
41.   (b)   Trehalose is a non-reducing sugar. It is made up to 2 molecules
            of glucose
42.   (c)     43. (a)        44. (d)
45.   (a)   Palmitic acid is one of the most common saturated fatty
            acids found in animals and plants. It has 16 carbons including
            the carboxyl carbon.