COURSE GUIDE
Course: Chem 221 –Biochemistry Semester: 2nd School Year: 2024-2025
Class Schedule: F 8:00-11:00AM Instructor: Jemima Krisiah A. Balagbis
Course Description
This course deals with the study of substances and chemical processes which occurs in living
organisms. It includes the identification of structures and functions of cellular components such as
proteins, carbohydrates, lipids, nucleic acids and other molecules, and determination of how they are
synthesized and degraded in an organism.
Course Outline
SCHEDULE TOPIC
WEEK 1 & 2 I. Introduction to Biochemistry
A. History of Biochemistry
B. Structure and Function of Cell
o Animal Cell
o Plant Cell
II. Fundamental Concepts of Biochemistry
C. Characteristics of living matter
o Levels of Organization in Life
D. Water
o Properties of Water
o Calculating the PH
o Acids, Bases, and Buffer systems
E. Introduction to different biomolecules
o Major and Minor Molecules in Food and their important
functions
WEEK 3 & 4 III. Carbohydrates
A. Monosaccharides
B. Disaccharides
C. Polysaccharides
D. Reactions of Monosaccharides
E. Isolation and Detection of Sugars
WEEK 5, 6 & 7 IV. Amino Acids, Peptides and Proteins
A. Structure and properties of amino acids
o Classifying Amino Acids according to their chemical
properties
B. Peptide bond formation
C. Peptide digestion
D. Protein Structure based on the level of organization
o Primary
o Secondary
o Tertiary
o Quaternary
E. Properties and functions of proteins
F. Isolation, Purification, and Quantification of proteins
WEEK 8 & 9 V. Lipids
A. Fatty Acids
B. Triacylglycerol
C. Sterols and Steroids
D. Terpenes
E. Eicosanoids
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F. Phospholipids
G. Isolation and Detection of Lipids
H. Membrane Transport Systems and Mechanisms
o Active Transport and Passive Transport
MIDTERM EXAMINATION
WEEK 10, 11, & 12 V I. Nucleic Acids
A. DNA vs RNA
B. Structure of Nucleotides
C. The Central Dogma
o Replication
o Transcription
o Translation
D. Mutation, Genetic defect, and Repair mechanisms
WEEK 13 & 14 VII. Introduction to Enzymes
A. Characteristics of Enzymes
B. General Classification of Enzymes
C. Factors affecting enzyme activity and reactions
D. Enzyme Kinetics
WEEK 15, 16, & 17 VIII. Metabolism
A. Catabolism vs Anabolism
B. Glycolysis
C. Pyruvate Oxidation
D. Kreb’s Cycle
E. Oxidative Phosphorylation
F. Metabolism of Proteins and Fats
WEEK 18 IX. Hormones and Vitamins
A. Classification and Characteristics of Hormones
o Mechanism of action of Hormones
B. Structure and Function of Water and Lipid Soluble Vitamins
FINAL EXAMINATION
Course Requirements
Course Learning Outcomes Required Output
By the end of the course the student The student must pass:
should be able to:
CLO1: Identify and differentiate essay type test/reflection paper/reaction
the different classes and structure of paper
biomolecules based on their physical and oral presentations/recitations
chemical properties; term exams
CLO2: Identify the different factors quizzes/exercises
affecting biomolecule’s activity in an organism; project
and
CLO3: Apply key concepts in
biochemistry to explain its practical
applications in the field of nutrition, agriculture,
medicine, pharmacy and allied fields.
Course Policies Grading System
1. Students must adhere to the standing Term Exams (40%)
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policies of the University.
2. Students must earn their grade. Just Class Standing (60%)
attending class will not allow students to earn
the points necessary to pass the course. - Attendance (10%)
Students must earn passing grades on - Class Participation (20%)
coursework. - Quizzes (30%)
3. Special examinations will only be permitted
after a counselling session with the guidance
counsellor or Dean and a special permit will be Semester Grade = Midterm Grade + Final Grade
required. 2
4. Grades. Completion of conditional grades
will adhere to the standard policy of the
University. INC grade will be complied by
submitting the lacking major criteria.
Conditional grades will be settled with an
examination.
5. Non-participatory behavior (such as sleeping
or text messaging) during lecture will be
treated as an absence. Three tardiness and
late will be equal to one absence.
References:
1. Nelson, D., M. (2008). Lehninger Principles of Biochemistry, 5th Edition. New York: W.H.
Freeman and Company.
2. Campbell, M., & Farrel, S., (2010). Biochemistry, 7th Edition. Brooks/COLE: Cengage Learning
3. Bettelheim et al. (2019). Biochemistry. C & E Publishing, Inc.
4. Ferrier, D.(2017). Lippincott’s Illustrated Reviews: Biochemistry, 7th edition. Lippincott Williams
& Wilkins: Baltimore
5. Garrett, R. and Grisham, C. (2017). Biochemistry, 6th ed. BROOKS/COLE: Cengage Learning:
Boston
6. McKee & McKee (2019). Biochemistry: An Introduction, 7th Edition. WCB-Mcraw-Hill
7. Nelson and Cox (2017). Lehninger Principles of Biochemistry, 7th Edition. Macmillan Learning
8. Stoker (2017). Biochemistry, 3rd Ediion. Cengage Learning
Consultation Schedule
Tuesdays and Thursdays
9:00 - 10:30AM
Prepared by:
JEMIMA KRISIAH A. BALAGBIS, RFP
Course Instructor, CFAS
Checked by:
BHERRA GRACE B. BONTIGAO, MMM
Program Head, CFAS
Approved by:
THERESE T. TORIANO, D.Fish.Tech.
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Dean, CFAS
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