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CHAPTER22
Ji
CHEMICAL COORDINATION
AND INTEGRATION
rr

Section-A : Questions Based on NCERT Textbook mr

1. Find out the incorrect statement: (c) Invertebrates possess very simple endocrine
(a) The neural system provides a point-to-point rapid system whereas a large number of chemicals act as
coordination among organs hormones in vertebrates
(b) The neural coordination is fast but short lived (d) Honnones are produced in trace amounts by
(c) The nerve fibres innervate all the cells of body ducted glands
(d) The neural system and the endocrine system jointly 5. Honnones are chemically :
coordinate and regulate the physiological (a) Steroids (b) Proteins
functions in the body (c) Amines (d) All of these
2. Honnones : 6. Identify the endocrine glands labelled as A, B, C, D, E
(a) Act as intercellular messengers and F:
(b) Are nutrient chemicals
(c) Act only as intracellular messengers
(d) Are secreted only by endocrine glands and no other
organs
3. Endocrine glands :
(a) Are ductless
(b) Like hypothalamus and pituitary are actually
neuroendocrine organs
(c) Secrete honnones
(d) Are related to all the options mentioned above
- ---1+--~ Pancreas
4. Choose the correct statement :
(a) Organised endocrine glands include pineal gland,
pituitary gland, pancreas, liver, ovary and testis
with primary endocrine functions llil:;::,~ Testis
Ovary
(b) In nervous system, the response is for long (in female) (in male)
duration whereas in endocrine system it is for short
duration
 II! Olemical Coordination and Integration!JI P-
-----
o,d
!!! niyrnus
A B

Pituitary
C

Pineal
D

Thyroid
E

Hypo-
•
Adrenal
(a) Steroid hormones
(b) Peptide hormones
(c) Electrical syn.apses
and thalamus
(1)
para- (d) Neurotransmitters
thyoid 11. Exocrine glands :
L-- -HYPO· Pituitary Pineal Thyroid Thymus Adrenal (a) Pour their secretion into the lymph or blood
(bl thalamus
and (b) Pour their secretion directly over the tissue
para-
thvmid whereas endocrine glands pour their secretion into
i-- Pineal Pituitar y Thyroid Thymus Adrenal lymph or venous blood
HypO-
(C) thalamus (c) Secrete hormones basically
..- Pineal Pituitar y Thyroid Hypo- Adrenal (d) Usually lack duct
TbymUS
(d) thalamu s
12. Which of the following is incorrect for hormo nes ?
- of the following statements are true (a) These initiate a reaction and also influences its rate
7• Find out which
(DI false (F) and choose the correct option. (b) These are highly specific in nature
I. The endocrine glands and hormr.ae producing (c) These are secreted in respon se to a partic ular
I diffused tissues/ cells are restricted to sex organs stimulus
only (d) These do not provide energy
n. Grastrointestinal tract, liver, kidney and heart 13. Hypothalamus is :
produce hormo nes (a) Connected to the pituita ry via a selend er stalk
m. Hypothalamus is the basal part of diencephalon called infundibulum
which contai n neuros ecreto ry cells called 'nuclei' (b) A physiological and anatom ical conne ction
that produ ce hormo nes between nervous system and endoc rine gland
IV. The hormo nes of hypoth alamu s regulate the (c) Both (a) and (b)
synthesis and secretion of anteri or pituitary (d) A part of mesen cepha lon
hormones 14. Read the following statem ents:
(i) The releasing hormo nes of hypot halam us alway s
Opli
I D m IV inhibits the secret ion of pituita ry hormo nes
CIIIS
(ii) GnRH stimul ates pituita ry synthe sis and releas e
T T
(a) T T of gonad otroph ins
(b) F F T T (iii) Somat ostatin is produ ced in hypot halam us and
F inhibits the releas e of growt h hormo ne from
(c) T T F
pituita ry gland
(d) F T T T (iv) Somat ostatin is also called 'grow th hormo ne
inhibi ting hormo ne' (GHIH)
a. All honnones : (v) Hypot halam us is conne cted to the anteri or lobe of
(a) Are lipid solubl e molec ules the pituita ry gland by hypop hysea l ponal veins
and to the poster ior lobe of pituita ry gland by
Cb) Are produ ced by endoc rine glands
axons of neuros ecrero ry cells
(c) Elicit the same respon se and are protei n molecules
Which of the. above statem ents are correc t ?
(d) Are carrie d to target cells via blood
9 (a) (ii), (iiO, (iv), (v) (b) (i) , (ii) , (iii)
• The inter-r elation ships betwe en the endoc rine and
(c) (i), (iv), (v) (cl) (i) only
nervous system s are especi ally appar ent in :
(a) A neuro n in a spinal cord
1s. The poster ior lobe of pituita ry gland is connected to
hypot halam us throu gh:
Cb) A brain cell in the cerebr al cortex
(a) Neurosecretory cells
(c) A steroi d produ cing cell in the adren al cortex
(b) Hypop hyseal veins
(d) A neuro secret ory cell in the hypot halam us
(c) Hypop hyseal arterie s
lO, The hypot halam us modu lates honno ne seretio n by
(d) Both (b) and (c)
anterior pituita ry by means of :
 440 \ti NCERT Biology Booster •!\
16. Which of the following is not incorrect? Th region of pituitary, commonly called
20
(a) The honnones of hypothalamus reach the pitui • an:erior pituitary produces GH, PRL, TSH, ACT
tary H, LH
gland th.rough a ponal circulatory system and and FSH .
regulate the functions of the anterior pituitary (a) Pars distalis (b) Pars intermedia
(b) The posterior pituitary is under the direc (c) Pars tuberalis (d) Neurohyphophysis
t neural
regulation of the hypothalamus 21, Neurohypophysis: . .
(c) Somatostatin inhibits the release of grow (a) Comprises par nervosa and pars mtennedia
th
honnone (b) Releases only one hormone called
melanocyte
(d) More than one stimulating honnone (MSH)
17. Study the diagrammatic representation of ~itu (c) Releases oxytocin and vasopressin
i~ and I

it relationship with hypothalamus and identify (d) Produces TSH and ACTH
the .
parts labelled as A, B, C, D and E : 22, Oxytocin and vasopressin are synthesised
:
A (a) In the pars nervosa
(b) By adenohypophysis
(c) By pars distalis and pars intermedia
(d) By hypothalamus and trarisponed axorially
to
neurohypophysis
23. Which of the following hormone is secr
eted by pars
intermedia ?
(a) MSH (b) Oxytocin
(c) FSH (d) LH
24. In human adults :
(a) Pars intennedia is almost merged with pars dista
lis
(b) Pars distalis is absent
(c) Both (a) and (b)
E (d)' Pars nervosa releases no hormone
Opd 25. Match the column :
A B C D E
ODS
Column-I Colu mn- n
(a) Hypo- Hypo· Ponal Posterior Anterior
I

thalamic thalamus circulation pituitary

A. Prolactin (i) Steroid hormone secretion
pituitary
neuron
B. ACTH (ii) Skin pigmentation regulation
(b) Hypo· Hypo- Portal Posterior
thalamw thalamic
Anterior C. LH and FSH (iii) Milk formation
circulation pituitary pituitary
neuron D. MSH (iv) Gonadal activity stimulation
(c) Posterior Hypo- Hypo- Ponal Anterior
pituitary thalamic thalamus circulation (a) A = (ii), B=
pituitary (iv), C =
(i), D = (iii)
neuron
(b) A = (iii), B= (iv), C =
(i), D = (ii)
(d) Hypo- Hypo- Portal Anterior Posterior (c) A= (ii),
thalamus thalamw circulation pituitary pituitary B= (iv), D = (iii)
(i), C =
(d) A= (iii), B= (i), C =
(iv) , D = (ii)
18. The pituitary gland is located in a bony cavit
y in the 26. The luteinizing hormone (Ll-l) :
sphenoid bone called
(a) Foramen cecum
--- (a) In males is also called interstitial cell stimu
lating
(b) Sella turcica hormone (ICSH)
(c) Optic canal (d) Foramen ovale (b) Activates leydig cells of testes
19. Adenohypophysis (anterior pituitary) : to secrete
testosterone
(a) Consists of pans distalis and intermedia
(c) Induces ovulation of fully mature Graafian follic
(b) Comprises mainly of pars intermedia and les
minorly and maintains the corpus luteum formed from the
of pars distalis
(c) Both (a) and (b) remnants of the Graafian follicles after ovulation
(d) ls related to all of the above
(d) Do not produce prolactin
 ,~ Olemical Coonhtion and Integration•] ~'[@,~
,1. 111 Jl]lles -~· : th .
(a) StiJDUJAteS synem and secr etio n of Oxy tocin (a) Ante rior pitu itary and adrmal gland
vasopressin from testi s
and {b) Post erio r pituitary and thyroid glan
d
(b) stimulates the synt hesi s and (c) Anterior pitu itary and posr erio rpitu itary
secr etion of
androgeDS from testi s
(d) Hypothalamus and ante rior piru itary
(c) SUpresses testi s deve lopm ent 35. If a pers on looses a larg e amo unt of wate r in
(d) }>elforms all of the abov e functions
a shor t
peri od of time, be/she may die from dehy
drat ion. ADH
SI- (irOWtb horm one {GH ) : can help reduce wate r loss thro ugh its imeracrio
n with
(a) Suppresses hepa tocy tes so that its targ et cells in the :
glucose is not
released into the bloo d (a) Bladder (b) Adrenal glan d
(b) Is the only aden ohyp ophy sis horm (c) Ureter (d) Kidn ey
one which .
direCtly linked to the bod y but othe r horm 36. The hypo thala mus :
ones ;
aden ohyp ophy sis basi cally cont rols othe (a) Functions only as an endo crin e targ et,
r glan ds having lots
(c) When over secr eted , results in stun ted of receptors on its cells
grow th
(d) If secreted in low amount, results {b) Functions only in neur onal tranSmiss
ion
in gigantism
29. 1be rorp us lute um secr etes prog este rone (c) Includes neur osec reto ry cells that term
and som e inat e in the
esaogen und er the acti on of : posterior pitu itary
(a) TSH (d) Does not have any horm one rece ptor
{b) Acr n s on its cells
(c) MSH 37. A prod ua of ante rior pitu itary glan d that
{d) lli caus es colo ur
so. Se)e a the gon adot roph in : changes in its targ et cells is :
(a) MSH (a) FSH {b) lli and TSH
{b) lli and FSH
(c) MSH (d) ACTH
(c) Oxytocin {d) MSH and hCG
38. In lactating mam mals , the two horm ones
SL Oiytocin : that prom ote
milk .synthesis and milk relea se, respectively,
(a) Aas on smo oth mus cles of our bod are :
y and stimulate (a) Prolactin and oxytocin
their cont ract ion
(b) FSH and lli
(b) Is relea sed into the bloo dstr eam
in resp onse to (c) Prol aain and calcitonin
stret chin g of cerv ix and uter us duri ng ~
r (d) Oxy tocin and prol actin
(c) Stim ulate s a vigo rous cont ract ion
of uter us at the 39. ADH is synthesised in the :
time of chil d birth
(a) Adenohypophysis {b) Hyp otha lamu
(d) Is relat ed to mor e than one opti on s
(c) Posterior pitu itary (d) Adrenal cort
12. The functions of vaso pres sin is : ex
40. Endocrine struc ture deri ved from nerv
(a) Constriction of bloo d vess els ous tissu e
include the :
Cb) That it stim ulat es reso rptio n of wate r
(a) Post erio r pitu itary and adre nal med ulla
(c) Prevents diuresis {b) Liver and panc reas
(d) All of the abov e (c) Anterior pitu itary and adre nal cort ex
33• Owing mam mali an labo r and
delivery, the cont racti on (d) Thymus and thyr oid glan d
of uterine mus cles is enha nced by oxytocin
. This is an 41. A trop ic horm one from the ante rior pinr
example of: itary glan d
regu lates the secr etion of :
(a) A nega tive feed back syst em (a) Thyroxine {b) Para thyr oid horm one
(b) A horm one that acts in an antagoni
sti~ way with (c) Epinephrine (d) Glucagon
anot her horm one 42. Which diso rder is correctly mat ched
Cc) lbe key role of post erio r pitu itary with the
glan d in malfunctioning of endo crin e glan d ?
regu latin g uter ine cont ract ion (a) Diabetes insipidus and post erio r pitu
(dY A horm one that is invo lved in a positive itary glan d
feedback {b) Gigantism and post erio r pitu itary
loop glan d
34· Portal bloo (c) Dwarfism and adre nal cort ex
d vessels conn ect two capi llary beds foun (d) Diabetes mellitus and para thyr oid glan
d d
in the:
C111 1a NCERT Biology Booster !II
43. The endocri ne gland include :
(a) Salivary gland
46. Which of the following do not synthesise honnone ?
(a) Neurobypopbysis
(b) Sweat gland (b) Pars interme dia
(c) Parathy roid gland (c) Both (a) and (b)
(d) Sebace ous gland and gall bladder (d) Anterior pituitary
44. Identify A, B, C, D and E for thyroid and 4 7,
parathyroid 'Herring bodies' or 'neuros ecretor y bodies' :
glands :
(a) Stores ACllt and PSH and represe nts tennina}
of axons from the hypoth alamus ~
(b) Are found in posteri or pituitar y
(c) Stores ADH and oxytocin
(d) Both (b) and (c)
48, What is the function of melato nin ?
(a) Influences metabolism, pigmentation, the
C E
menstru al cycle as well as our defense capability
(b) Maintains normal rhythm s of sleep-wake cycle and
A body temper ature
8
(c) Regulates 24-hou r (diurna l) rhythm of our body
Opti (d) All of the above
om A B C D E
49. The largest endocri ne gland is:
(a) Dorsal view Ventral view Parathyroid Isthmus (a) Thyroid
Thyroid (b) Ovary
11:Jands gland (c) Testes (d) Pituitar y
(b) Ventral Dorsal view Parathyroid Thyroid lsthmUJ
view 11:lands gland 50. Pineal gland is located on the :
(c) Dorsal view Ventral view Thyroid Parathyroid Thyroid (a) Ventral side of forebrain
11:land sdand 11:land (b) Ventral side of hindbra in
(d) Dorsal view Ventral view Parathyroid Thyroid Isthmus (c) Dorsal side of forebra in
glands gland
(d) Ventral side of forebrain
45. Identify A, B, C and D from the table provided : 51, The' follicul ar cells of thyroid synthesise :
Hormo ne (a) Thyroxine (T4 ) only
Target organ ,
(b) Tetraio dothyro nine (T ) only
4
A Adrenal cortex (c) Triiodothyronine (T3 ) and T
Prolactin 4
8 (d) Iodine
C Male swnads 52. ~e two lobes of thyroid gland are interconnected with \
Oxytocin D
(a) Thin flap of epitheli al tissue called isthmus I
Opti ;~
A B C D (b) Thick flap of connec tive tissue called isthmus
008
(c) Thin flap of connec tive tissue called isthmus
(a) MSH Mammary ICSH Uterus
S(!and (d) Thick flap of epithel ial tissue called isthmus
AClli Mammary 53. The thyroid gland :
(b) ICSH Mammary
gland gland and (a) Is compos ed of four lobes located on the either side
uterus of trachea
(c) FSH Female LH Mammary Cb) Is composed of two pairs of lobes located on the
S(onads S(land either side of oesoph agus
(d) Oxytocin Mammary Prolactin Mammary (c) Is compos ed of follicles and stromal tissues
gland gland and
uterus (d) Is located in the lower trachea
 I[! Oiemical Coordination and IntegraOOD'~I
ch myroid follicle
54- ea) [s compose d of follicular cellsr enclosing a cavity 59. Find the incorrect mar.ch ·
(a . .
(bJ rs exocnne m narure
(c) 5eereres thymosin
Opd
Oil&
... •
(d) 5eereres TSH . (a) l'etraiodothyronine or lodinared ammo acid
Eind out which of the folloWlllg statemen ci are ture (T) thyroxine
55• / false' (F) and chose the correct option.: (b) l.>mrein.
Thyrocalcitonin or
L H:ypelthy roidism causes cretinism calcitonin
IL Iodine-is essential for the normal rate of hormone (c) Steroid
Adrenocorticottopin
synthesis in. the thyroid hmmone
IIL In adult women, hypodryr oidism may cause
(d) T riiodothyro nine fodinared. aminn acid
menstru.al cycle to become irregular
IV. Hyperthy roidism can occur due to cancer of 60. The calcium level in. the body is under the control of 7
thyroid gland or due to the developm enr of
(a) Thyroid gland (b) Parathyr oid gland
nodules of thyroid gland
( c) Thymus (d ) More than one

-
.

•
~

61. T3 and T4 produced by the thyroid gland, aresymh esise

I a m IV from _ _ __ and the amino acid _ _
(a) F T T (a) Iodine, tyrosine
T
(b) Iodine, arginine
(b) F F T T (c) Chlorine, tyrosine
(tj T T T T (d) Chlorine, lysine
(cl) T F 62. Calcitoni n :
T T
(a) Reduces Ca~ in blood, opposing the effecrs of
56. Deficiency of iodine : pararliyr oid hormone (PTH)
(a) Results in enlargem ent of thyroid (b) Stimulate s steroid producti on
(b) Results in shrinkag e of thyroid gland and (c) Increases ADH level
commonl y called goitre (d) Increases Ca:!+- in blood as does PTH
(c) During pregnanc y results in mental retardati on, 63. Calcium and phospho rus metabol ism is disrurbe d due
low intelligen ce quotient, deaf mutism and to the malfunct ioning of :
acromega ly ( a) Parathyr oid (b) Pancreas
(d) Lead to more than one option ( c) Salivary glands (d) Both (b) and. (c)
57. Hormones secreted by thyroid gland is : 64. The blood Ca 2+- level goes down due to the deficienc y
(a) TCT (b) T3 , T4 and TSH of:
(c) Both (a) and (b) (a) Parathorm .one (b) Cal.citoa in
(d) TSH
58. Read the following statemen ts w.r.t. thyroid glands : (c) Thyroxin e (d) Glncoge n
Ci) It secretes a steroid hormone called 65. Diabetes insipidus occurs due to:
thyrocalcironin (a) Hypersecretion of vasopres sin
(ii) Helps in rnaiotain ing water and electroly te Cb) Hype.rsecretion of ADH
balance ( c) Both (a) and (b)
(iii) Controls the metaboli sm of carbohyd rates, (d) Hyposec retion of ADH
proteins and fats with the help of thyroxin e 66. A tropic hormone from anterior pituitary gi.a:nd
(iv) R.egu}ares basal metaboli c rate (BMR) regulaces the secretion of:
.
(v) Suppon the process of red blood cell formatio n (a) Thyroxine (b) Calciton in
How many of the above statemen ts are correct ? (c) Epinephr ine (d) Glucago n
(a) Four (b) Three 67. In humans, w parathyroid glands ~ present on
(c) Two (d) Five
the CB) side of the thyroid gland. - ~-0 - each in
two lobes of the thyroid gland.
 [!i4 f I[• NCERT Biology Booster • JI
Opd 75, PTH:
A B C
OM (a) Acls on bones and stimulates the process of bone
(o) Pour Front One pair
resorption (dissolution/demineralisation)
(b) Mobilises Ca21- from bones into the blood
(b) Pour Back One pair
(c) Helps co increase Ca 21- levels in the blood
(c) Four Back One (d) Performs all the above functions
(d) Four Back Two pair
76. Which of the following is wrong ?
(a) Alongwith TCT, PTH plays a significant role In
68, In females LH stimulates the corpus luteum to secrete : calcium balance in the body
(a) FSH and relaxin (b) PTH is a hypercalcemic hormone
(b) Progesterone exclusively (c) The secretion of PTH is regulated by the circulating
(c) Testosterone exclusively levels of calcium Ions
(d) TCT is secreted by parathyroid gland
OI
(d) Progesterone and some estrogen OI
69, Thyroxine is involved in regulating : 77. The thymus gland :
(1
(a) Is a secondary lymphoid organ of immune system
(a) BMR
(b) Secretes the steroid hormone called thymosin
(b) Water and electrolyte balance
(c) Blood Ca 2+- level (c) Degenerates in old individuals resulting in a
decreased production of thymosins
(d) More than one
(d) Is located near kidney
70. The development and maturation of T-lymphocytes
78. Thymosins :
occur in:
(b) Thymus
(a) Has no role in humoral immunity
(a) Parathyroid
(c) Pituitary (d) Thyroid (b) Play a major role in the differentiation of
I
71, Which of the following is nor incorrect for 'pars
T-lymphocytes which provide cell-mediated
immunity
nervosa'?
(c) Are secreted by parathyroid gland
(a) It stocks and release hormones synthesised by
hypothalamus (d) Are not produced in old people above the age of 60
years
(b) Jr synthesises many hormones of Its own
79, Read the following statements :
(c) It Is present in childhood but absent in adults
(i) The thymus gland is composed of two identical
(d) It is functionless in adults
lobes located on the dorsal side of heart and aorta
72, Gonadotropic hormones are released by :
(ii) Thymosins provide cell-mediated immunity as
(a) Pars-nervosa (b) Gonads
well as humoral immunity
(c) Sperm and ova (d) Adenohypophysis
(iii) Thymosins promote production of antibodies
73. One reason a person might be severly overweight is due
(iv) Our body has one pair of adrenal glands, one at
to :
the posterior part of each kidney
(a) A higher than normal level of melatonin
(v) Adrenal gland is composed of the centrally
(b) Hyposecretion of oxytodn
located adrenal cortex and peripheral adrenal
(c) A defect in hormone release from the posterior medulla
pituitary
Which of the above statements are correct ?
(d) An undersecretion of thyroxine
(a) (i), (ii), (iii)
74, The parathyroid glands :
(b) (iv), (v)
(a) Secretes a peptide hormone called parathyroid
(c) (iii), (iv), (v)
hormone (PTH)
(d) (iii) only
(b) Forms thyroxjne and PTH
(c) Helps in immoblislng calcium of bone
(d) Performs all of the above functions
 I[! Olemical Coordination and Integration •JI
SO· Jdentify A, B, C and D for the diagram : 86. ACTH release is stimulated by :
C (a) Aldosterone (b) CRH
B
(c) TSH (d) Oxytocin
87. Adrenaline and noradrenaline :
(a) Are emergency hormones
A (b) Represent the polypeptide hormones
(c) Are slowly secreted in response to stress and
during emergency
(d) Both (a) and (c)
88. Read the following statements :
Kidney (i) Catecholamines inhibits the breakdown of
glycogen
Opd (ii) Catecholamines can lead to increase in glucose
A B C D
OIII concentration of blood
Fat Adrenal Adeno- Neuro- (iii) Catecholamines stimulates breakdown of lipids
(1)
s?land hvooohvsis hvnoohvsis and proteins
(b) Excess Adrenal Adrenal cortex Adrenal (iv) Adrenaline and nor-adrenaline increases
orotein S?land medulla alertness, pupilary dilation, piloerection and
(t) Fat Adrenal Adrenal cortex Adrenal sweating
S?land medulla (v) Adrenal cortex secretes only two hormones
(d) Fat Adrenal Adrenal gland Adrenal Which of the above statements are incorrect ?
cortex medulla
(a) (ii), (iii)
81. Identify the catecholamine : (b) (i), (v)
(a)Adrenaline (c) (ii), (iv)
(b)Epinephrine and norepinephrine (d) (i), (iii), (v)
(c) Noradrenaline 89. Aldosterone :
(d) More than one (a) ls chemically peptide
82. Which of the hormones increase the heart beat, the (b) Is chemically steroid and is responsible for
Strength of heart contraction and the rate of secondary sexual character development
respiration? (c) Disturbs water and electrolyte balance
(a) Adrenaline and noradrenaline (d) ls produced by the zona glomerulosa of adrenal
Cb) Adrenaline cortex
(c) ACI1f and glucagon 90. Match the column for the different layers of adrenal
Cd) ACI1f and insulin cortex:
83· Select the gonadotropins :
Column-I Col1111111-n
(a) 0xytocin
A. Zona reticularis (i) Middle layer
Cb) Ui and FSH
B. Zona glomerulosa (ii) Inner layer
(c) Somatostatin
C. Zona fasciculata (iii) Outer layer
(d) Sornatostatin and oxytocin
84
• Ovulation in females and release of androgens in males (a) A = (i), 8 = (ii), C = (iii)
is under the control of : (b) A = (iii), 8 = (ii) , C = (i)
(a) Ui (b) FSH (c) A = (ii), B = (iii), C = (i)
I (c) ADH (d) TSH (d) A= (iii), B = (i), C = (ii)
s. The 'fight or flight' gland is :
(a) Pituitary (b) Thymus
(c) Adrenal (d) Kidney
 r

441 I[.• NCERT Biology Booster • JI

91. Identify A, B, C and Din the table : 11. Aldosterone acts mainly_at the re:ial tubules 111d
stimulates the :eabsorpt10n of N~ and water~
Hormone Chemical excretion of K and phosphate 10ns
nature Source Functions
m. Cortisol increases the WBC count in blood
A Steroids Zonula Water and IV Cortisol stimulates high immune response

Gluco- B
2lomerulosa
Adrenal
elecrrolYte balance
Gluconeogenesis Opd I D m IV
-
con:icoids conex ODS
C Steroids D Secondary sexual T F F T
(11)
character
develooment (b) F F T T
-
T T F F
Opd (c)
A B C D
o.m T T T T
(d)
(a) Mineralo- Steroids Sex- Zona reticularis
conicoids conicoids 96. Identify A, B, C and D in the given table :
(b) Aldosterone Steroids Sex- Zona fasciculata
conicoids Mineralocortlcold Gl ucocorticotd
(c) Cortisol Peptide Sex- Zona Secreted by zona A
conicoids 2lomerulosa !Zlomerulosa
(d) Sex- Steroids Sex- Zona reticularis B Its secretion is under the
conicoids conicoids control of ACTH
C D
92. Which of the following is correct ?
(a) Aldosterone is the main glucocorticoid in our body Opd A B C D
(b) In our body, cortisol is the main mineralocorticoid ODS
(c) Glucocorticoids stimulate gluconeogenesis but not Secreted by Its It stimulates It stimulates
(a)
lipolysis and proteolysis zona secretion is K~ glucon~
(d} Glucocon icoids inhibit ce.llular uptake and reticularis under the excretion
control of
utilisation of amino acids
renin-
93. Cortisol : angiotensin
(a) Stimulates RBC production svstem
(b) Produces anti-inflamatory reactions and (b) Secreted by It is under It stimulates It stimulates
suppresses the immune response Lona the control Na• gluc o n ~
fasciculate of ACTH excretion
(c) Maintains the cardio-vascular system as well as the and K~
kidney functions resom tion -
(d) Is related to more than one option (c) ~creted by Its It stimulates It stimulattS
94. Adrenal cortex : zona secretion is K'" gl uconeogenesis
(a) Secretes small amoun t of androgenic steroids fasciculata under the excretion
control of and Na•
(b) Has no role in stimulating the secondary sexual renin- resorption
characters
---
angiotensin
(c) The kidney hormone renin normally inhibits svstern
aldosterone secretion from adrenal glands (d) Secreted by It is under It stimulates It somulattS.
(d) Secretes small amount of vasopressin
95. Find out which of the following statements are true
(T)/ false (F) and choose the correct option :
zona
!llomerulosa
the control K+ and Na• gluconeogenesis
of ACTH

97. Glucocorticoids include :

excretion
--
I. Adrenal con ex honnones play a role in the (a) Conisone
growth of axial hair, pubic hair and facial hair (b) Conisol
during puberty (c) Corticosterone
(d) All of these
 ,. Chemical Coordination and Integra tion II M
,.. Match the column :
102. Choose the odd one out w.r.t. chemica l nature :
column -I Column-lJ (a) FSH (b) Thyrox ine
(Hormo nes) (Target tissue) (c) Oxytocin (d) Progest erone
A. Aldosterone (i) Heart, skeletal muscles 103. Secretin is secreted by :
smooth muscles, blood (a) Duoden um and jejunum
vessels
Adrenalin and (b) Jejunum and ileum
B. (ii) Gonads
noradrenaline (c) Stomac h and oesopha gus
C. Estrogens and (iii) Liver (d) Pancrea s
androgens 104. Epineph rine is respons ible for :
o. Cortisol (iv) Kidney (a) Vasoconstriction in skin
(b) Vasodia lation in brain
(a) A= (i), B = (iv), C = (iii), D = (ii)
(c) Develop ment of seconda ry sexual charact er
(b) A= (ii), B = (i), C = (iv), D = (iii)
(d) More than one option
(c) A= (iv), B =
(iii), C = (i), D (ii) = 105. Which of the following is respons ible for the
(d) A= (iv), B = (i), C = (ii), D = (iii)
develop ment of seconda ry sexual charact ers in
99, Pancreas : females?
(a) ActS as endocri ne gland only (a) Estrogen (b) Testost eron
(b) ActS as both exocrin e and endocri ne gland (c) Androgens (d) ANF
(c) Contain about 1 to 2 million Islets of Langerh ans in 106. Hormon es of amino acid origin is not secreted by :
a normal human which represen ts 10%-12 % of the (a) Gonads (b) Adrena l
pancreatic tissue (c) Thyroid (d) Both (a) and (b)
(d) Both (b) and (c)
107. Choose the incorrec t stateme nts :
100. Match the column : (a) Cholecystokinin stimula tes the pancrea tic enzyme s
Column-I I Column -n and gall bladder contrac tion
(b) Estrogen, progest erone and testoste rone are
A. Insulin (i) Glycogenolysis
steroids
(ii) Hyperglycemia (c) Only testes and ovary produe androge ns
I (iii) Hypoglycemia (d) Melaton in is secreted by pineal gland
B. Glucagon (iv) Glycogenesis 108. Match the column :
(v) Reduces cellular glucose
uptake Column -I Column -lJ
(vi) Enhances cellular glucose A. Glucagon (i) ~cells
uptake
I (vii) Deamination of amino acids B.
C.
Insulin
Androgens
(ii) Corpus luteum
I (viii) Stimulat es protein synthesis (iii) a - cells
D. Progesterone (iv) Leydig cells
(a) A= (i), (ii), (iii), (iv)
B = (v), (vi), (vii), (viii) (a) A = (iii), B = (i), C = (iv), D = (ii)
Cb) A = ('") c· ) ( ') ( "')
W , lV , Vl , Vlll (b) A = (i), B = (iii), C = (iv), D = (ii)
B = (i), (ii), (v), (vii) (c) A= (ii), B = (i), C = (iii), D = (iv)
(c) A= (iii), (iv), (v), (vi) (d) A = (iii), B = (ii), C = (iv), D = (i)
B = (i), (ii), (vii), (viii) 109. Which one is false for glucago n?
(d) A= (v), (vi), (vii), (viii) (a) Stimula tes glycogenesis
B = (i), (ii), (iii), (iv) (b) Maintai ns glucose homeos tasis in blood with the
101
· Insulin and glucagon are : joint effect of insulin
(a) Peptides (b) Hexoses (c) Acts mfinly on hepatoc ytes and stimula tes
(c) Steroids (d) Fatty acids glycogenolysis
(d) Causes hypergl ycemia
 ,,.
I

~ IE NCERT Biology Booster -JI

110. Insuli n : 115. Match the colum n :
. .
(a) Acts only on hepato cytes Colunin•I· Cohunn-D
(b) Mainl y acts on hepato cytes and adipocytes A. Gastrin (i) Contraction of gall bJadder
(c) Is a hyper glycem ic hormo ne
B. CCK (il) Stimulates gastric Julee
(d) Rapid ly chann elises glucose from hepatocytes and secretion
adipo cytes into blood ANF (iii) Stimulates adrenal COrtt:z to
C.
111. A perso n suffer ing from diabet es mellitus is under release aJdosterone
carbo hydra te free diet but even then she excretes out D. Angiotensin (iv) Maintains blood pressuie
gluco se in urine. This is due to the fact that : and blood volume
(a) Amin o acids get discharged from liver into the blood A = (ii), B = (i), C = (iii), D = (iv)
(a)
(b) Fats of adipo cytes get catabo lised to form glucos
e
A= (i), B = (iv), C = (ii), D = (iii)
(b)
(c) Both (a) and (b)
A = (ii), B = (iv), C = (i), D = (iii)
(c)
(d) Glyco gen gets discha rged from muscles into the A = (ii), B = (i), C = (iv), D = (iii)
(d)
blood
116. Which of the following is not incorr ect ?
112. Find out which of the following statem ents are true
(a) Estrogen is synthesised and secreted mainlybythe
CT)/ false (F) and choos e the correc t option :
growi ng ovaria n follicels
I. Andro gens influe nce libido in males
(b) After ovulat ion, the ruptu red follicle is convened
II. Prolo nged hypog lycem ia lead to diabet es mellitus into corpus callosum, which mainly secretes
ill. Diabe tes mellit us is associ ated with loss of proge steron e
gluco se throu gh urine and forma tion of keton e (c) Progesterone promo tes uterin e contraction
bodie s
(d) Each ovary norma lly produ ces multiple Qva duriog
N . Andro gens regula te the develo pment , matur ation each menst rual cycle
and functi ons of male accessory sex organ s
117. The two group s of steroi d hormo nes produced by avart
Optf
ODS
I D m . IV
. is:
(a) Estrogen and proge steron e
(a) T F T F (b) Estrogen and andro gen
T T (c) Testo steron e and andro gen
(b) T F
(d) Corticosteroids and estrog en
F F
(c) T T 118. Read tl)e following statem ents :
F F T T (i) Proge steron e acts on mamm ary glands _and
(d)
stimu lates the forma tion of mamm ary alveoli
113. The under produ ction of hormo nes by th~ adren
al (ii) Estrogens smn"ulates the activities of femalt
cortex alters carbo hydra te metab olism causm g acute secop dary sex organ s
weakn ess and fatigu e leadin g to the diseas e called : (iii) Estrogens regula te femal e sexua l behaviour
(a) Addis on's diseas e (b) Exoph thalm ic goitre (iv) Proge steron e suppo rts impla ntatio n
(c) Grave 's diseas e (d) Diabe tes insipidus (v) Proge steron e suppo rts pregn ancy
7
114• Which of the follow ing is true for andro gens
? How many of the above statem ents are correct
(a) It is respo nsible for the devel opme nt of epididymis, (a) Three (b) Two
vas defere ns, semin al vesicles, prosta te gland and (c) Five (d) Four
ureth ra 119. Choos e the correc t statem ent : bich art
(b) It stimu lates muscu lar growt h, growt h ~f facial
~d
(a) Horm ones are secret ed by some tissues w
axillary hair, aggre ssiven ess and low pitche d voice not endoc rine gland s ~
11 st
in males (b) The atrial wall of our heart secretes
(c) It plays a major stimu lato~ role in hormo ne ANP (atria l natriu retic factor)
sperm atoge nesis and has anabo lic effects on
prote in and carbo hydra te metab olism
(d) More than one
(c) ANF increa ses the blood pressu re
(d) When blood pressu re decrea ses, ANF JS
which constr icts the blood vessels
. ~ttd
I
eJ
 II! Olemlcal Coordination and Integration~I B
T wsterone is an example of a chemical signal that 127. Identify :
,so,~ the cells_ that syn~esis~ it, the neighbouring nypersecredon
cells in the tesns, alongwi~ distant cells outside the Hyposecredon
Hormone resul18 reaults
gonads. Thus, testosterone 1s an example of :
Diabetes meUitus A
(a) An autocrine signal Insulin
Exo oitre
(b) An endocrine signal Th oxin B
Mineralocorticoid C Conn's syndrome
(c) A paracrine signal
and lucocorticoid and cushin disease
(d) An autocrine signal, a paracrine signal and an
Parathormone Tetan D
endocrine signal
, A paracrine signal that relaxes smooth muscle cells is :
111 Opd D
(a) Vitamin-D (b) Nitric oxide A B C
ODS
(c) Cortisol (d) ADH Addison's Osteoporosis
(a) Hypo- Cretinism
122, Pro5t88landins are local regulators whose chemical glvcemia disease
structure is derived from : Cretinism Addison's Osteoporosis
(b) Hyper-
(a) Fatty acids (b) Steroids sdvcemia disease
(c) Amino acids (d) Oligosaccharides (c) Hyper- Cretinism Osteo- Addison's
113, Nitric oxide and epinephrine, both : glycemia porosis disease
(a) Are involved in 'fight-or-flight' response (d) Hypo- Addison's Cretinism Osteoporosis
glycemia disease
(b) Bind to the same receptor
(c) Function as neurotransmitter 128. Identify A, B, C and D in the diagrammatic
(d) Cause a reduction in the blood glucose level representation of mechanism of hormone action.
114, Choose the odd one out w .r.t. hormones of gastro-
intestinal tract.
(a) GIP (b) CCK
""'A
(c) Erythropoietin (d) Secretin and gastrin Response 1
125, Match the column :
- . i
d
Column-I Cohunn-D
i
BiochemicaJ responses
A. Gasoin ( i) Stimulates secretion of
water and bicarbonate ions .u.
.u.
8. Secretin (ii) Stimulates secretion of D.
pancreatic enzymes and bile
juice Opd
C. GIP (iii) Stimulates the secretion of ODS
A B C D
HCI and pepsinogen
D. CCK (a) Steroid Receptor Physiological cAMP
(iv) Inhibits gastric secretion hormone response
(I) A= (ill), B = (ii) , C = (ivJ, D = (i) (b) Protein Receptor cAMP Physiological
hormone response
(b) A= (i), B = (ii) , C = (iv), D = (iii)
(c) Protein cAMP Receptor
~c) A== (iii), B = (i), C = (iv), D = (ii) Physiological
hormone
response
(d) ~ == (iv), B = (i), C = (ii), D = (iii) Estrogen Receptor
126 (d) Generation of Physiological
• The Juxtaglomerular cells of kidney produce _ __ _ second response
hormone called _ _ _ _ which stimulates messenger
erytlu-opoiesis :
(a) Glycoprotein, erythropoietin
Cb) 0ligosaccharide erythropoietin
(c) Peptide, renin '
(d) Sreroid, erythropoietin
 I~ NCERT Biology Booster • ]I
129. Match the column :
132. How many' of the hormones given in the box interact
Column-I Column-n with plasma membrane bound receptors (M) and
Steroids intracellular receptors (I) ?
A. (i) Thyroid hormones
LH, MSH, Epinephrine, Insulin, lodothyronine,
B. Amino acid derivative (ii) Insulin, glucagon, Cortisol, Glucagon, Estradiol, Progesterone,
hypothalamic and Testosteron e
pituitary hormones
C. lodothyronines (iii) (a) M = 5, l = 5 (b) M = 8, I= 2
Cortisol, estradiol,
testosterone and (c) M = 6, l = 4 (d) M = 4, I= 6
progesterone 133. Choose the incorrect statement :
D. Peptide, polypeptide, (iv) Epinephrine (a) Intracellular receptors are mostly present in the
protein
plasma membrane of cell
(a) A = (i), B = (iv), C = (iii), D = (ii) (b) Membrane-b ound receptors are present on the cell
(b) A= (ii) , B = (i), C = (iv), D = (iii) membrane of target cells
(c) A= (iii) , B = (i) , C = (ii), D = (iv) (c) Each hormone receptor is specific to one hormone
(d) A = (iii), B = (iv), C = (i), D = (ii)
only
(d) Steroid hormones mostly regulate gene expression
130. Hormone receptors are :
by the interaction of hormone-receptors complex
(a) Present on plasma membrane
with the genome
(b) Intracellula r
134. In a positive feedback system where hormone A alters
(c) Proteins
the filllOunt of protein X :
(d) Related to more than one option (a) ft. decrease in X always causes a decrease in A
13 1. Identify A, B, C and D in the diagrammat ic
(b) A decrease in A always produces an increase in X
representat ion of hormone action :
(c) An increase in X always produces a decrease in A
(d) An increase in A always produces an increase in X
135. Which category of signals exerts its effects on the target
cells by binding to membrane bound receptor proteins?
(a) Estrogens
(b) Neurohorm ones, estrogens and androgens
(c) Neurohormones
(d) Vitamin-D
Genome 136. A cells with membrane- bound proteins that selectively
, ----mRNA bind a specific hormone is called hormone's :
l (a) Regulatory cell

r
Physiological
(b) Target cell
(c) Secretory cell
response (d) Endocrine cell
137. The reason that aldosterone affects only a small
Optl number of cells in the body is that :
A B C D
ODS (a) Only it target cells get exposed to aldosterone
(a) Protein Nuclear Second Protein (b) It is unable to enter the non-target cell
hormone envelone messen!Zer (c) Only its target cells contain aldosterone receptors
(b) Steroid Nuclear Hormone- Proteins (d) Non-target cells destroy aldosterone before it can
hormone envelope receptor produce any effect
comolex
1 3 8. A chemical signal operating in a paracrine manner is
(c) Estrogen Nuclear AMP and Steroids
ea2• one that :
envelooe
(a) Evokes responses from all parts of the vascular
(d) Progesterone Nuclear IP3 Steroids
envelooe tissue system
 IE Chemical Coordination and Integratlon~ I -

(b) Requires transport in the blood before it can act on (c) The steroid and peptide hormone must bind to the
its target cells same receptor protein
(c) Is active at a neuronal synapse (d) The steroid hormone affect the synthesis of effector
(d) Must move through heart before · it reaches its protein, whereas peptide hormones activate the
target cell effector proteins already present in the cell
139, A hormone X activates the cAMP second messenger 141. For hormones that homeostatically regulate the
system in its target cells. The greatest response by a cell cellular functions :
would come from : (a) A negative feedback typically regulates hormone
(a) Injecting a molecule of hormone X into the secretion
cytoplasm of the cell (b) The circulating level of hormone is held constant
(b) Applying a molecule of cAMP to the extracellular through a series of positive feedback loops
fluid surrounding the cell (c) Both lipid-soluble hormones and water soluble
{c) Injecting a molecule of cAMP into the cytoplasm of hormones bind to intracellular protein receptors :
the cell (d) Both (b) and (c)
(d) Applying a molecule of hormone X to the 142. Suppose that a substance X is secreted by one cell,
extracellular fluid surrounding the cell travels via interstitial fluid to a neighbouring cell, and
140. When a steroid hormone and a peptide hormone exert produces an effect on that cell. All of the following
similar effects on a population of target cells, then : terms could describe this substance except :
(a) The steroid hormones affect the activity of certain (a) Prostaglandin
proteins within the cell, whereas peptide hormone (b) Paracrine signal
directly affect the processing of mRNA (c) Pheromone
(b) The steroid hormones affect only the release of (d) Neurotransmitter
proteins from the target cell, whereas peptide
hormones affect only the synthesis of proteins that
remain in the target cell
 I

An sw ers (Section-A)
2. (a)
J: 3. (d) 4. (c) . 5. (d) 6.
~,r;
(b) l
r -~ --
7• . (d)• 8. (d) 9. (d) 10. {b)
(b) 12. (a) u. (c) 1!"14 . 1 (a) 15. (a) 16. (d) . 1'7•. ' (b) 18. (b) · 19. (a) 20.. (a)
.
21. (c) 22. (d) 23. (a) 24. (a) 25. · (d) 21.- (d) • 27. · (b)
* • ;,• 28. (b) 29. (d) 30. Cb)
31. (d) 32. (d) ~ ...
s3. (d) 34. (d) , 35. (d) 36. (c) ~37. (c) 38. (a) 39. (b) 40. (a)
41. (a) 42. (a) 43. (c) 44. (d) 45. (b) ~-- I (a) \· 47,.t (d) (d) so.
S1. (c) 52. (c) u. (c) 54. (a)
. (a)
48. 49. (a) (c)
55. 56. (a) 57.• (a) 58. (a) .': 59.- (c)
6L (a)
..
64.
l 60. (d)
62. {a) 63. (a) .... (a) 65. '66. (a) t. 61~" (b)
:.-,!() •
I (d) 1
68!.. (d) . 69. , (d) 70. (b)
I I • I
·~!J •
7.L (a) 72. (d) 73. (d) 14. (a) 75. (d) ~76. 1 {d) · 11.: · (c)
4

I
18. (b) 79. (a) 80. (c)
81. (d) 82. (a) 83. {b) &4. (a) ' as. (c) 86. (b) 87. (a) 88. (b) 89. (d) 90. (c)
91: {a) 92. (d) .c 93. (d) 94. (a) 91. (c) 96. (c) 97~ (d) , 98. (d) 99. (b) 100. (b)
(a) 102 . (d) 103 . (a) ,.104 . (d) 105 . (a) 106 . (a) 107 . (c)
j

.108 . (a) 109 . (a) 110. (b)

{b) 112 . (b) 113 . (a) 114 . (d) 11&. (d) 116 . (a) 1117 . (a) tl8 . (c) 119 . (a) 120. (d)
121 . (b) 122 . (a) 123. {c) 112 4. (c) 125 . (c) 126 . (a) 1127-. (a) 128 . {b) 129 . (d) 130. (d)
131 . (b) 132 . (a) 133 . (a) .. .
134 (d) 13&. (c) 186 . (b) f 187 . (c)
'1
138 . (c) 139• (d) 140. (d)
141 . (a) 142 . (c)
' R V V'