Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - APRIL-2019
Time: Three Hours Max. Marks: 80 Marks
Pathology – Paper III (RS-3 Scheme)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe the techniques of collection of specimen for cervical cytology.
2. Write in detail ABO grouping and Rh typing.
3. Mention the different blood components prepared in the blood bank with shelf life and storage
conditions.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Quality control in blood banking
5. HLA antigens and their significance
6. Cytological fixatives
7. Preparation of cell block
8. Cytologic criteria of malignancy
9. May Grunwald stain
10. Transfusion reaction
11. Methods of bleeding donors
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Cytospin preparation
13. Mention three diseases transmitted by blood transfusion
14. Mention methods of identification of sex chromatin
15. Apheresis
16. List two applications of immunohistochemistry
17. What is flow cytometry
18. List two automated equipments in cytology
19. Mention stains used in FNAC of breast.
20. Significance of Bombay Blood group
21. Two anticoagulants used in blood bank
22. Significance of Direct Coomb’s test
23. Mention criteria for blood donor selection
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 28-Aug-2020
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Write a note on different blood grouping systems. Discuss the different methods to perform blood
grouping and typing.
2. Discuss culture of peripheral blood lymphocytes. Add a note on the different banding techniques.
3. Discuss methods of collection, fixation, processing and staining of cytological specimens.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. What is Du? How it is detected?
5. List the subgroups of Blood group A. How are they detected and confirmed?
6. What are the different blood collection systems available?
7. Uses and advantages of FNAC
8. Haemolytic disease of newborn
9. Nomenclature of chromosomes
10. Crossmatching of blood
11. List any three donor adverse reactions and their preventive measures.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Sex chromatin identification
13. Name five normal components of cervical smear.
14. Autologous blood transfusion
15. Name any three minor blood group systems.
16. Cryoprecipitate
17. MGG stain
18. Bombay blood group
19. Direct Coomb’s test
20. List three reasons for donor deferral.
21. Chromosomes in cancer
22. Karyopynotic index
23. List three fixatives used in cytology.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 16-Dec-2020
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe in detail the procedure of FNAC. List the advantages, disadvantages and limitations of
FNAC.
2. Classify adverse transfusion reactions. Write in detail sample collection and work up of transfusion
reactions.
3. Describe the Sample collection of CSF for lab investigation. Describe cell counting of CSF Samples.
List the Variations of CSF findings in Tuberculous and Pyogenic.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Liquid based cytology
5. Describe quality control parameters of packed Red Blood Cells.
6. Applications of Immunohistochemistry
7. Describe the cytological findings in malignant thyroid lesions.
8. Detection of subgroups of A and B blood grouping systems
9. Structural chromosomal aberrations
10. Describe progressive and regressive stains.
11. Procedure for Cell block preparation and advantages
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. List the government authorities of blood bank administration.
13. List 3 advantages of computer software in blood bank.
14. Mention 2 indications of exchange transfusion.
15. What are the pre-requisites of autologous transfusion?
16. Mention 4 Thyroid neoplasms.
17. Down’s Syndrome
18. Mention 2 normal Maturation indices.
19. Mention 4 special types of microscopes.
20. List 2 advantages of Leuco depleted blood products.
21. Mention 4 equipments used in blood component separation Laboratory.
22. Mention 4 indications of flow cytometry.
23. What the advantages of karyotyping?
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 16-Dec-2022
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Mention the different components prepared in blood bank with their uses and storage conditions.
2. Describe the Broncho Alveolar Lavage procedure. Add a note on principle and procedure of MGG
stain.
3. Describe various Chromosomal banding techniques.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Discuss the procedure for cell block preparation.
5. Describe any one method of blood grouping procedure.
6. Discuss major cross matching technique.
7. Automation in cytology
8. Laminar Air flow equipment.
9. Pleural effusion – cell count and cell typing methods.
10. Autologus transfusion.
11. Fine needle aspiration cytology procedure.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Mention four ovarian tumors.
13. Du testing and its significance.
14. List two applications o Immunohistochemistry.
15. Mention criteria for blood donor selection.
16. Describe Mesothelial cells.
17. List anticoagulants used in blood bank.
18. Maturation index.
19. List the tumors with Psammoma bodies.
20. Name the organisms detected on pap smear.
21. List the advantages of spray fixatives.
22. Name the various dyes used in Papanicolaou stain
23. Difference between transudate and exudate.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 07-Jan-2022
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER - III (RS3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. List the components prepared from whole blood. Discuss in detail the preparation, storage and
uses of each of them.
2. Discuss various chromosomal banding techniques.
3. Describe the processing of body fluids in the cytology lab. Add a note on MGG staining.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Normal histology and cytology of salivary glands.
5. Procedure of Papanicolaou stain.
6. Procedure of blood collection in the blood bank.
7. Discuss procedure for preparation of cell block.
8. Biomedical waste disposal in blood bank.
9. Down’s syndrome.
10. Equipments used in Karyotyping laboratory.
11. Liquid Based Cytology.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Give three examples for autosomal recessive diseases.
13. Spray fixatives.
14. Image analysis.
15. Bronchoalveolar lavage.
16. Transfusion transmitted infections.
17. Use and care of microscope.
18. Platelet concentrate.
19. Bombay blood group.
20. Du test.
21. Samples used for karyotyping.
22. List three advantages of FNAC.
23. List the hormonal indices in cervical cytology.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 20-May-2023
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER - III (RS3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe the procedure of selecting a donor for blood donation. Add a note on screening tests done
on collected blood.
2. What is FNAC? Discuss uses, advantages and disadvantages.
3. What is an ideogram? Discuss the procedure of Karyotyping using peripheral blood.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Histology and normal cytology of respiratory tract.
5. Urine Cytology.
6. Cytological Fixatives.
7. Autologous Blood Transfusion.
8. Quality Control in Blood Bank.
9. Bombay Blood Group.
10. Turners Syndrome.
11. Chromosomal abnormalities in Cancer.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Maturation Index.
13. Regressive staining.
14. Use and care of microscope.
15. Cryoprecipitate.
16. Colchicine.
17. Sex chromatin.
18. Apheresis.
19. List three application of immunohistochemistry.
20. Blood bags.
21. CSF in tuberculous meningitis.
22. List three donor adverse reactions.
23. List stains used in cytology.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 11-Jul-2022
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER - III (RS3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. What is the principle of FISH? Explain the use of this technique in cytogenetics.
2. Describe the various blood transfusion reactions and the work up for the same.
3. Discuss in detail about processing of various body fluids for cytology.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Bethesda system of reporting cervical cytology.
5. Enumerate the reasons for pale and dark nuclear staining in PAP smears.
6. Principle and procedure of GTG banding.
7. Describe the FNAC technique. Mention its advantages and disadvantages.
8. What is reverse blood grouping? What are its advantages?
9. List the Blood components and their methods of preparation and storage.
10. Coomb’s test.
11. Cytology of CSF and its in differential diagnosis of meningitis.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Shorr’s stain.
13. HSIL cytology.
14. Role of Urine cytology in transplant patients.
15. Barr body.
16. Name the equipments used for tissue culture.
17. Name three transfusion transmitted infections.
18. Name the types of administrative organisation of blood banks in India.
19. Rh incompatibility.
20. Clinical significance of testing for HLA antigens.
21. Automation in Cytology.
22. Explain briefly X-linked inheritance with examples.
23. Techniques of specimen collection for cervical cytology.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - 04-Aug-2021
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe the principle and staining technique of PAP Stain.
2. Enumerate the types of structural abnormalities in chromosomes with examples.
3. Write about different components of blood and explain preparation of platelet concentrates.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Stains used for chromosome study
5. Coomb’s test
6. ABO blood group system
7. Transfusion reactions
8. Flow cytometry
9. Techniques of collection of specimen for cervical study
10. Cytological fixatives
11. Du testing and its significance
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Cryoprecipitate
13. Identification of sex chromatin
14. Preparation of Harris haematoxylin
15. Triploidy
16. Cross matching in blood bank
17. Use of microscope
18. Maturation index
19. Name three transfusion transmitted infections.
20. Sputum examination for AFB
21. Inverted microscope
22. Bombay blood group
23. Method of collection of urine for cytology
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (MLT) Degree Examination - OCT-2019
Time: Three Hours Max. Marks: 80 Marks
Pathology – Paper III (RS-3 Scheme)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Enumerate blood transfusion reactions. Write on investigations of transfusion reactions.
2. Define Karyotype. Describe the procedure of karyotyping of malignant tumor.
3. Describe the various methods of sample collection and processing of cervical smears.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. ABO blood group
5. Inverted microscope
6. Autologous transfusion
7. PAPanicoloau stain
8. Sex chromatin identification
9. Flow cytometry
10. Cell block preparation
11. Detection of biochemical markers in cell
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Name 2 applications of Immunohistochemistry
13. Du testing and its significance
14. Enumerate blood components
15. Normal cytology of urine sediment
16. Cryoprecipitate
17. Triploidy
18. Name 4 anticoagulants used in blood bank
19. Oncogenes
20. Colchicines
21. Cytological fixatives
22. Down’s Syndrome
23. Principle of Shorr stain
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (M.L.T) Degree Examination – 29-Nov-2023
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Give an account of cervical cytology screening for malignant and non-malignant conditions.
Add a note on radiation changes.
2. Write about blood components preparation, storage and uses of each of them.
OR
Discuss methods of Karyotypic analysis.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Procedure of Papanicolaou’s stain.
4. Cytology of cerebrospinal fluid.
5. Urine cytology.
OR
Fine needle aspiration cytology of salivary glands.
6. Laminar air flow equipment.
7. Direct and indirect Coomb’s test.
8. Chromosomes in neoplasia.
9. HLA antigens.
10. Methods of bleeding donors.
OR
Transfusion transmitted diseases.
11. Investigation of transfusion reaction.
12. Rh blood group system.
SHORT ANSWER 10 x 3 = 30 Marks
13. Fixatives used in cytology.
14. May-Grunwald Giemsa stain.
15. Three uses of flow cytometry.
16. Three applications of Immuno cytochemistry.
17. Name three enzymes used in tissue culture.
18. Uses of inverted microscope.
19. Bombay blood group.
20. Duffy blood group system.
21. Three causes of mismatched blood transfusion.
22. Hormonal cytology
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (M.L.T) Degree Examination – 20-May-2023
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Discuss principle, procedure of flow cytometry.
2. Enumerate the transfusion reactions. Discuss the process of investigating a transfusion
reaction.
OR
Discuss the process of culturing peripheral lymphocytes. Add a note on different types of
banding techniques.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Papanicolaou staining.
4. Rh blood group system.
5. Cytologic criteria for malignancy.
OR
Quality control in cytology laboratory.
6. Indications for platelet transfusions. How do you store platelets?
7. Write histology and normal cytology of respiratory tract.
8. Chromosomal abnormalities in cancer.
9. Hemolytic disease of the newborn.
10. What is Barr Body? Add a note on different staining methods used.
OR
Bombay blood group.
11. Describe the method of processing sputum for Cytologic examination.
12. Plasmapheresis.
SHORT ANSWER 10 x 3 = 30 Marks
13. FNAC of breast.
14. Cytology of carcinoma of cervix.
15. Oncogenes.
16. Significance of HLA antigens.
17. Du test.
18. Three anticoagulants used in blood bank.
19. Spray fixatives.
20. Use and care of microscope.
21. Triploidy.
22. Colchicines.
III Year B.Sc. (MLT) Degree Examination - 29-Nov-2023
Rajiv Gandhi University of Health Sciences, Karnataka
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER - III (RS3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Write in detail the principle and procedure of Papanicoloau’s staining method.
2. What are the types of anticoagulants used in blood bank? Describe their composition and
mechanism of action.
3. Explain in detail the steps involved in peripheral lymphocyte culture for karyotyping.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. What is autologous blood transfusion? Add a note on its advantages and disadvantages.
5. Fixatives used in cytology.
6. Flow cytometry – principle and applications.
7. Write about the screening methods for infective material in blood donors.
8. Cell block preparation.
9. Applications of Fine needle aspiration cytology.
10. List Banding techniques and explain any one method.
11. Principle, procedure and applications of immunocytochemistry.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Liquid based cytology.
13. Radiation changes in Pap smear.
14. Laminar air flow.
15. Name three blood grouping systems.
16. Name the cells seen in pap smear.
17. Give examples of immortalized cell lines and its uses.
18. Define progressive stain.
19. Sex chromatin.
20. Cryoprecipitate.
21. Direct Coomb’s test.
22. Name three cytology samples from respiratory tract.
23. Name three distinguishing cytological features of malignant and benign cells.
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year B.Sc. (M.L.T) Degree Examination – 16-Dec-2022
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. What is Fine needle aspiration cytology? Discuss the procedure, advantages and
disadvantages of FNAC over biopsy.
2. Define a Karyotype. Discuss the procedure of Karyotyping using peripheral blood
lymphocytes.
OR
Discuss various selection criteria used while selecting a donor for blood donation.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Anatomy, histology and normal cytology of female genital tract.
4. Anticoagulants used in blood banking.
5. Autologous transfusion.
OR
Quality control in blood bank.
6. Preservation of immortalized cell lines.
7. Cryoprecipitate.
8. Demonstration of Barr body in buccal smear.
9. Difference between benign and malignant tumours.
10. Flow cytometry.
OR
May Grunwald Geimsa staining method.
11. Oncogenes.
12. Coomb’s test.
SHORT ANSWER 10 x 3 = 30 Marks
13. List three fixatives used in cytology.
14. Name three minor blood group systems.
15. Name three applications of immunohistochemistry.
16. Inverted microscope.
17. Normal cytology in urine sediment.
18. Mention three transfusion transmitted infections.
19. Maturation index.
20. Liquid based cytology.
21. Exfoliative cytology.
22. Histology of salivary glands.
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