Code No: BP602T PCI SET - 1
III B. Pharmacy II Semester Supplementary Examinations, NOVEMBER - 2022
PHARMACOLOGY-III
Time: 3 hours Max. Marks: 75
Note: 1. Question paper consists of three parts (Part-I, Part-II & Part-III)
2. Answer ALL (Multiple Choice) Questions from Part-I
3. Answer any TWO Questions from Part-II
4. Answer any SEVEN Questions from Part-III
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
PART –I
1. i) ___________ is selective b2 agonist. (1M)
a) salbutamol b) phenoxybenzamine
c) tolazoline d) none of above
ii) ---------the main approach of peptic ulcer treatment (1M)
a)Neutralization of gastricacid
b) Eradication of helicobacter pylori
c) Inhibition of gastric acid secretion
d) All the above
iii) -----------The drug belonging to membrane stabilizing agent (1M)
a) Sodium cromoglycate b) Zafirleucas
c) monteleucast d) omeprazole
iv) Chloramphenicol has the following unwanted effects: (1M)
a) Nephrotoxicity b) Pancytopenia c) Hepatotoxicity d) Ototoxicity
v) ---------the drug belonging to aromatase inhibitors: (1M)
a) Octreotide b) Anastrozole c) Flutamide d) Tamoxifen
vi) Indicate the side effect of Theophyline: (1M)
a)Bradycardia
b) Increased myocardial demands for oxygen
c) Depression of respiratory center
d) Elevation of the arterial blood pressure
vii) Which drug analog of prostaglandin E1 (1M)
a)Misoprostole b) Sucralfate
c) omeprazole d) Pirenzipine
viii) Indicate the drug that cause metabolic alkalosis (1M)
a) Sodiumbicarbonate b) Cimetidine
c) misoprostole d) vitamins
ix) Sulfonamides have the following unwanted effects: (1M)
a) Hematopoietic disturbances b) Crystalluria
c) Nausea, vomiting and diarrhea d) All of the above
x) Mechanism of action of cyclosporine A is: (1M)
a) Complement-mediated cytolysis of T lymphocytes
b) ADCC towards T lymphocytes
c) Inhibits calcineurin d) Compete for Fc receptors with autoantibodies
xi) Bactericidal effect is: (1M)
a) Inhibition of bacterial cell division
b) Inhibition of young bacterial cell growth
c) Destroying of bacterial cells
d) Formation of bacterial L-form
1 of 3
|''|'||||''|''|'''||
Code No: BP602T PCI SET - 1
xii) Which of the following antibiotics contains a beta-lactam ring in their chemical (1M)
structure :
a) Penicillins b) Cephalosporins
c) Carbapenems and monobactams d) All groups
xiii) Amphotericin B has the following unwanted effects: (1M)
a) Psychosis
b) Hpekalaemia,Renal impairment, anemia
c) Hypertension, cardiac arrhythmia
d) Bone marrow toxicity
xiv) the unwanted effects of Metronidazole: (1M)
a) Nausea, vomiting, diarrhea, stomatitis
b) Hypertension
c) Disturbances of peripheral blood circulation
d) All of the above
xv) Isoniazid has following unwanted effect: (1M)
a) Cardiotoxicity b) Hepatotoxicity, peripheral neuropathy
c) Loss of hair d) Immunotoxicity
xvi) -------the antimalarial drug belonging to 8-aminoquinoline derivatives: (1M)
a) Doxycycline b) Quinidine
c) Primaquine d) Chloroquine
xvii) ------- the drug, inhibiting oxidative phosphorylation in some species of (1M)
helminthes:
a) Niclosamide b) Piperazine
c) Praziquantel d) Mebendazole
xviii) the drug, inhibiting uncoating of the viral RNA: (1M)
a) Vidarabine b) Rimantadine
c) Acyclovir d) Didanozine
xix) mechanism of action of alkylating agents is: (1M)
a) Producing carbonium ions altering protein structure
b) Producing carbonium ions altering DNA structure
c) Structural antagonism against purine and pyrimidine
d) Inhibition of DNA-dependent RNA synthesis
xx) Specific anti-dotes for organophosphorous compounds poisoning is (1M)
a) Disulfiram b) BAL c) Pralidoxime d)Flumazenil
PART –II
2. a) What is Carminative? What is their use in pharmacology? (5M)
b) Classify antiemetics? Explain their mechanism and uses. (5M)
3. a) Describe the mechanism of action, Adverse effects and clinical uses of (5M)
Chloramphenicol and Streptomycin.
b) Discuss the pharmacology of Acyclovir. (5M)
4. a) Classify Cephalosporins? Write the mechanism of action, Adverse effects and (5M)
Clinical uses of Cephalosporins.
b) Write the principle of treatment of Arsenic poisoning. (5M)
2 of 3
|''|'||||''|''|'''||
Code No: BP602T PCI SET - 1
PART -III
5 Classify anti-diarrheal agents. Explain the treatment employed in diarrohea. (5M)
6 Discuss the Pharmacology of Respiratory stimulant. (5M)
7 What is Cotrimoxazole.Give its therapeutic uses and Mechanisam of action. (5M)
8 Write the Mechanisam of action, adverse effects and Clinical uses of Tetracyclins. (5M)
9 Discuss the pharmacology of Albendazole. (5M)
10 Discuss the Pharmacology of Salbutamol. (5M)
11 Explain in detail about Urinary tract infection. (5M)
12 Enumerate the general principles of treatment of Poisoning. (5M)
13 Add a note on treatment and symptoms of lead poisoning. (5M)
3 of 3
|''|'||||''|''|'''||
