POTASSIUM PERMANGANATE MOUTHWASH
FORMULA:
o 1 in 4000 ml solution means 1g of solute is present in 4000 ml i.e., 4000
ml of solution has 1000 mg of KMno4.
Therefore, 60 ml of solution should contains
1000/4000 X 60 = 15 mg of KMno4
o Since the sensitivity of the balance is 100mg, 15 mg can’t be weighed
accurately using the balance. So, a concentrate solution is prepared from
which a volume equivalent to 15 mg is measured out and diluted.
o 100 mg of KMno4 is weighed and dissolved in water up to 100 ml
o 15ml of solution will contain 15mg of KMno 4. Hence 15ml of the
solution is measured and made up to 60 ml using purified water to
obtain 60 ml of 1 in 4000 solution of KMno4.
LABEL:
POTASSIUM PERMANGANATE MOUTHWASH (60 ml)
(Not to be consumed)
Name: Age/Sex:
DIR: Sufficient quantity to be used as mouthwash
twice or thrice daily.
Date of Preparation: Dispensed by:
FOR EXTERNAL USE ONLY
Ex. No: 5 POTASSIUM PERMANGANATE MOUTHWASH
Date:
AIM:
To dispense 60ml of 1: 4000 solution of Potassium permanganate
mouthwash.
DEFINITION:
Mouthwash is an aqueous solution which is most often used for its
deodorant, refreshing, antiseptic properties and for control of plague.
It may contain alcohol, glycerine, synthetic sweeteners, flavouring and
colouring agents.
PRINCIPLE:
Potassium permanganate (KMno4) is an oxidizing agent which liberates
nascent oxygen, it oxidizes the bacterial protoplasm and kills the bacteria.
PROCEDURE:
1. 100 mg of KMnO4 is weighed and taken in a glass beaker.
2. Added 30 ml of distilled water to it and made up to 100 ml (This is
1mg/ml solution).
3. 15 ml of the above solution is taken in a measuring cylinder and made
up to 60 ml using distilled water (This is 1: 4000 solution).
4. The above solution is transferred to a plain bottle with a proper label.
CLINICAL USES:
Potassium permanganate (KMno4) is generally used to disinfect water.
It is also used as an antiseptic.
It is used as a mouth wash for treating Gingivitis and Halitosis (bad
breath).
Different concentrations of Potassium permanganate (KMno4) have
various uses.
1 in 2000 solution - used for gastric lavage
1 in 4000 solution - as mouth wash
1 in 10000 solution - as vaginal irrigation