Psychological
Disorders
     Anxiety
   Disorders,
  Depressive
 Disorders, and
 Schizophrenia
   (Psychotic
   Disorders)
 © Worth Publishers
What we’ll seek to
understand...
 ! What does it mean to have a mental
   disorder?
 ! Defining and classifying disorders
 ! Anxiety disorders, including OCD
   and PTSD
 ! Mood disorders, including
   depression and bipolar disorder
 ! Schizophrenia
 ! Sample of other disorders:
       ! Dissociative disorders
       ! Eating disorders
       ! Personality disorders
 ! Rates, vulnerability, and protective
   factors
Why Learn about Psychological
Disorders?
Reasons for curiosity:
!personal familiarity with
psychological symptoms
!knowing someone else
with the disorder
!hearing about how
prevalent and socially
devastating some
disorders have become
in society
!wanting to learn more
about mental health and
human nature
Perspectives on Psychological
Disorders
! Defining psychological      Questions to Keep in Mind
  disorders
! Thinking critically about   How do we decide when a set of
  ADHD                        symptoms are severe enough to
! Understanding                be called a disorder that needs
  psychological disorders                treatment?
! Classifying
  psychological disorders      Can we define specific disorders
                                clearly enough so that we can
! Labeling psychological      know that we’re all referring to the
  disorders                     same behavior/mental state?
! Insanity and
  responsibility              Can we use our diagnostic labels
                              to guide treatment rather than to
                                     stigmatize people?
Psychological disorders are:
   patterns of thoughts, feelings, or
   actions that are deviant, distressful,
   and dysfunctional.
             Terms from the Definition
             ! Disorder refers to a state of mental/
               behavioral ill health.
             ! Patterns refers to finding a collection
               of symptoms that tend to go together,
               and not just seeing a single symptom.
             ! For there to be distress and
               dysfunction, symptoms must be
               sufficiently severe to interfere with
               one’s daily life and well being.
             ! Deviant means differing from the
               norm.
                            Defining Deviance:
“Deviant”?                The Role of Context and
                                  Culture
! To deviate, in          !Context: whether a behavior
  general, means to       varies from expectation
  vary from what          depends on the situation in
                          which the behavior occurs
  typically would         "Yelling for hours is not
  happen.                 deviant when it happens at a
! In psychology, a        football game.
  behavior or mental      !Culture: these painted faces
  state is considered     might seem deviant when
  deviant by a culture    viewed from a different culture
  when it is different
  from what would be
  expected in that
  culture.
! A disorder may also
  be a deviation from a
  typical developmental
  pathway.
    Is Attention-Deficit/
Hyperactivity Disorder (ADHD)
         a disorder?
! Is it deviant? Do some people have a level of
  inattentiveness, impulsiveness, or restlessness
  that goes beyond laziness or immaturity?
! Is it distressful? Is the person enjoying being
  energetic, or are they frustrated that they can’t
  sustain focus?
! Is there dysfunction? Are the symptoms
  harmless fun, or do they negatively impact work
  and relationships?
Understanding the Nature of
Psychological Disorders
! One reason to diagnose a disorder is to make
  decisions about treating the problem.
! To treat a disorder, it helps to understand the
  nature/cause of the psychological symptoms.
! Based on older understanding
  of psychological disorders,
  treatments have included:
  exorcising evil spirits,
  beatings, caging/restraint,
  and
        Pinel’s New
         Approach
                                                 From the humane
! Philippe Pinel (1745-1826) and others          view to the scientific
  sought to reform brutal treatment by           view of the mentally
  promoting a new understanding of the nature    ill:
  of mental disorders.                           Pinel’s humane
! Pinel proposed that mental disorders were      environmental
  not caused by demonic possession, but by       interventions improved
  environmental factors such as stress and       lives but often did not
  inhumane conditions.                           effectively treat mental
! Pinel’s “moral treatment” involved improving   illness
  the environment and replacing the asylum                   But
  beatings with patient dances.                            then…
                           The discovery that the disease
The Medical                of syphilis causes mental
                           symptoms (by infecting the
   Model                   brain) suggested a medical
                           model for mental illness.
! Psychological disorders can
  be seen as
  psychopathology, an
  illness of the mind.
! Disorders can be
  diagnosed, labeled as a
  collection of symptoms that
  tend to go together.
! People with disorders can
  be treated, attended to,
  given therapy, all with a
  goal of restoring mental
  health.
 The Biopsychosocial Approach
Mental disorders
can arise in the
interaction
between nature
and nurture
caused by biology,
thoughts, and the
sociocultural
environment.
Cultural Influences on Disorders
         Culture-bound syndromes are
           disorders which only seem to
            exist within certain cultures;
           they demonstrate how culture
          can play a role in both causing
              and defining a disorder.
Examples:
Bulimia Nervosa: binging/purging, in the United
  States
Running amok: violent outbursts, in Malaysia
Hikikomori: social withdrawal, in Japan
Classifying Psychological
Disorders
                            The Diagnostic and
Why create                   Statistical Manual
classifications of mental
illness? What is the        !It’s easier to count
value of talking about      cases of autism if we
diagnoses instead of        have a clear
just talking about          definition.
individuals?                !Versions: DSM-IV-
1.Diagnoses create a        TR, latest version
verbal shorthand for        DSM-5 (May 2013)
referring to a list of      !The DSM is used to
associated symptoms.        justify payment for
                            treatment.
2.Diagnoses allow us to
statistically study many    !It’s consistent with
similar cases, learning     diagnoses used by
to predict outcomes.        medical doctors
                            worldwide.
3.Diagnoses can guide
treatment choices.
Categories of
 Diagnoses
Critiques of Diagnosing with the
              DSM
1. The DSM calls too many people
   “disordered.”
2. The border between diagnoses, or
   between disorder and normal, seems
   arbitrary.
3. Decisions about what is a disorder
   seem to include value judgments; is
   depression necessarily deviant?
4. Diagnostic labels direct how we view
   and interpret the world, telling us
   which behavior and mental states to
   see as disordered.
Stigma and Stereotypes
Many people think a diagnostic
label means being seen as
tainted, weak, and weird.
Because of this, many
psychologists believe we should
use extreme caution in
diagnosing and labeling.
             However:
!these negative views/stigma
come from popular cultural views
of mental illness, and not from
the DSM. [Does a diabetes
diagnosis create stigma? No.
Bipolar diagnosis? Yes.]
!the DSM may contain the
information to correct inaccurate
perceptions of mental illness.
Insanity and Responsibility
! Jared Loughner shot many
  people, including a U.S.
  Representative, in 2011.
! Loughner had
  schizophrenia and
  substance abuse problems,
  a combination associated
  with increased violence.
To what degree, if any,
should he be held
responsible for his
actions?
 What is the appropriate
 consequence?
Anxiety Disorders
     GAD: Generalized anxiety
            disorder
          Panic disorder
             Phobias
    OCD: Obsessive-compulsive
            disorder
    PTSD: Post-traumatic stress
            disorder
  GAD: Generalized
  Anxiety Disorder
! Emotional-cognitive
  symptoms include
  worrying, having anxious
  feelings and thoughts
  about many subjects,
  and sometimes “free-
  floating” anxiety with no
  attachment to any
  subject. Anxious
  anticipation interferes
  with concentration.
! Physical symptoms
  include autonomic
  arousal, trembling,
  sweating, fidgeting,
  agitation, and sleep
  disruption.
Panic Disorder:
  “I’m Dying”
A panic attack is not just an
“anxiety attack.” It may include:
!many minutes of intense dread or
terror.
!chest pains, choking, numbness,
or other frightening physical
sensations. Patients may feel
certain that it’s a heart attack.
!a feeling of a need to escape.
Panic disorder refers to repeated
and unexpected panic attacks, as
well as a fear of the next attack,
and a change in behavior to avoid
panic attacks.
Specific Phobia
A specific phobia is more than
just a strong fear or dislike. A
specific phobia is diagnosed
when there is an
uncontrollable, irrational,
intense desire to avoid the
some object or situation.
Even an image of the object
can trigger a reaction--“GET IT
AWAY FROM ME!!!”--the
uncontrollable, irrational,
intense desire to avoid the
object of the phobia.
       Some Fears and Phobias
What trends are
evident here?
Which varies
more, fear or
phobias? What
does this imply?
                Some Other Phobias
Agoraphobia is the           Social phobia refers to an
avoidance of situations in   intense fear of being watched
which one will fear having   and judged by others. It is visible
a panic attack, especially   as a fear of public appearances
a situation in which it is   in which embarrassment or
difficult to get help, and   humiliation is possible, such as
from which it difficult to   public speaking, eating, or
escape.                      performing.
 Obsessive-Compulsive Disorder [OCD]
! Obsessions are intense, unwanted
  worries, ideas, and images that
  repeatedly pop up in the mind.
! A compulsion is a repeatedly
  strong feeling of “needing” to carry
  out an action, even though it doesn’t
  feel like it makes sense.
! When is it a “disorder”?
   ! Distress: when you are deeply
     frustrated with not being able to
     control the behaviors
                     or
   ! Dysfunction: when the time and
     mental energy spent on these
     thoughts and behaviors interfere
     with everyday life
     Common OCD Behaviors
Percentage of children and adolescents with OCD
reporting these obsessions or compulsions:
                       Common pattern: RECHECKING
                       Although you know that you’ve
                       already made sure the door is
                       locked, you feel you must check
                       again. And again.
  Post-Traumatic
  Stress Disorder
      [PTSD]
 About 10 to 35 percent of
 people who experience trauma
 not only have burned-in
 memories, but also four weeks
 to a lifetime of:
! repeated intrusive recall of
   those memories.
! nightmares and other re-
   experiencing.
! social withdrawal or phobic
   avoidance.
! jumpy anxiety or
   hypervigilance.
! insomnia or sleep problems.
                                     Resilience and
    Which People get                 Post-Traumatic
                                     Growth
!
             PTSD?
    Those with less control in the   Resilience/recovery
    situation                        after trauma may
                                     include:
!   Those traumatized more
    frequently                       !some lingering, but
                                     not overwhelming,
!   Those with brain differences     stress.
!   Those who have less resiliency   !finding strengths in
!   Those who get re-traumatized     yourself.
                                     !finding connection
                                     with others.
                                     !finding hope.
                                     !seeing the trauma
                                     as a challenge that
                                     can be overcome.
                                     !seeing yourself as
                                     a survivor.
   Understanding Anxiety Disorders:
Explanations from Different Perspectives
Psychodynami        Classical         Operant
      c/         conditioning:     conditioning:
  Freudian:      overgeneralizin     rewarding
  repressed      g a conditioned     avoidance
   impulses         response
Observational       Cognitive       Evolutionary:
  learning:        appraisals:       surviving by
 worrying like    uncertainty is   avoiding danger
    mom              danger
      Understanding Anxiety
       Disorders: Freudian/
    Psychodynamic Perspective
! Sigmund Freud felt that
  anxiety stems from
  repressed childhood
  impulses, socially
  inappropriate desires,
  and emotional conflicts.
! We repress/bury these
  issues in the
  unconscious mind, but
  they still come up, as
  anxiety.
  Classical Conditioning                   Operant Conditioning
       and Anxiety                             and Anxiety
! In the experiment by John B.           ! We may feel anxious in a
  Watson and Rosalie Rayner in             situation and make a
  1920, Little Albert learned to feel      decision to leave. This
  fear around a rabbit because he          makes us feel better and our
  had been conditioned to associate        anxious avoidance was just
  the bunny with a loud scary noise.       reinforced.
! Sometimes, such a conditioned          ! If we know we have locked a
  response becomes                         door but feel anxious and
  overgeneralized. We may begin to         compelled to re-check,
  fear all animals, everything fluffy,     rechecking will help us
  and any location where we had            temporarily feel better.
  seen those, or even fear that those    ! The result is an increase in
  items could appear soon along with       anxious thoughts and
  the noise.                               behaviors.
! The result is a phobia or
  generalized anxiety.
  Observational
  Learning and
     Anxiety
! Experiments with humans
  and monkeys show that
  anxiety can be acquired
  through observational
  learning. If you see
  someone else avoiding or
  fearing some object or
  creature, you might pick up
  that fear and adopt it even
  after the original scared
  person is not around.
! In this way, fears get
  passed down in families.
  Cognition and
     Anxiety
! Cognition includes worried
  thoughts, as well as
  interpretations, appraisals,
  beliefs, predictions, and
  ruminations.
! Cognition includes mental
  habits such as
  hypervigilance (persistently
  watching out for danger). This
  accompanies anxiety in
  PTSD.
! In anxiety disorders, such
  cognitions appear
  repeatedly and make
  anxiety worse.
Examples of Cognitions that
   can Worsen Anxiety:
 Cognitive errors, such as believing that
   we can predict that bad events will
                happen
   Irrational beliefs, such as “bad things
  don’t happen to good people, so if I was
             hurt, I must be bad”
  Mistaken appraisals, such as seeing
  aches as diseases, noises as dangers,
        and strangers as threats
 Misinterpretations of facial expressions
  and actions of others, such as thinking
        “they’re talking about me”
       Biology and Anxiety:
    An Evolutionary Perspective
      1. Human phobic 2. Similar but non-phobic
         objects: Snakes objects: Fish
                   Heights Low places
             Closed spaces Open spaces
                  Darkness Bright light
3. Dangerous yet non-phobic subjects:
We are likely to become cautious about, but not phobic
about: Guns, Electric wiring, Cars
  ! Evolutionary psychologists believe that
    ancestors prone to fear the items on list #1 were
    less likely to die before reproducing.
  ! There has not been time for the innate fear of list
    #3 (the gun list) to spread in the population.
Biology and Anxiety: Genes
                                Genes and
! Studies show that          Neurotransmitters
  identical twins, even   !Genes regulate levels of
  raised separately,      neurotransmitters.
  develop similar         !People with anxiety have
  phobias (more           problems with a gene
  similar than two        associated with levels of
  unrelated people).      serotonin, a neurotransmitter
! Some people seem        involved in regulating sleep
  to have an inborn       and mood.
  high-strung             !People with anxiety also
  temperament, while      have a gene that triggers high
  others are more         levels of glutamate, an
  easygoing.              excitatory neurotransmitter
! Temperament may         involved in the brain’s alarm
  be encoded in our       centers.
  genes.
     Biology and Anxiety: The
               Brain
! Traumatic
  experiences can
  burn fear circuits
  into the amygdala;
  these circuits are
  later triggered and
  activated.
! Anxiety disorders
  include overarousal
  of brain areas
  involved in impulse
  control and habitual   The OCD brain shows extra
  behaviors.             activity in the ACC, which
                         monitors our actions and
                         checks for errors.
                           ACC = anterior cingulate gyrus
Mood Disorders
 Major depressive disorder [MDD]
 is:
     ! more than just feeling
       “down.”
     ! more than just feeling sad
       about something.
                 Bipolar disorder is:
                    ! more than “mood swings.”
                    ! depression plus the problematic
                      overly “up” mood called “mania.”
Criteria of Major Depressive Disorders
    Major depressive disorder is not just one of these
    symptoms.
    It is one or both of the first two, PLUS three or more
    of the rest.
! Depressed mood most of the day, and/or
! Markedly diminished interest or pleasure in activities
! Significant increase or decrease in appetite or weight
! Insomnia, sleeping too much, or disrupted sleep
! Lethargy, or physical agitation
! Fatigue or loss of energy nearly every day
! Worthlessness, or excessive/inappropriate guilt
! Daily problems in thinking, concentrating, and/or making
  decisions
! Recurring thoughts of death and suicide
      Major Depression:
Not Just a Depressive Reaction
              ! Some people make an
                unfair criticism of
                themselves or others with
                major depression: “There
                is nothing to be depressed
                about.”
              ! If someone with asthma
                has an attack, do we say,
                “what do you have to be
                gasping about?”
              ! It is bad enough to have
                MDD that persists even
                under “good”
                circumstances. Don’t add
                criticism by implying the
                depression is an
                exaggerated response.
Depression is Everywhere
Depression shows up in
people seeking treatment:
                              Depression: The “Common
!Phobias are the most         Cold” of Disorders?
common (frequently
experienced) disorder, but    Although both are
depression is the #1 reason   “common” (occurring frequently and
people seek mental health     pervasively), comparing depression
services.                     to a cold doesn’t work.
Depression appears            Depression:
worldwide:                    !is more dangerous because of
!Per year, depressive         suicide risk.
episodes happen to about 6    !has fewer observable symptoms.
percent of men and about 9    !is more lasting than a cold, and is
percent of women.             less likely to go away just with time.
!Over the course of a         !is much less contagious.
lifetime, 12 percent of       And…depressive pain is beyond
Canadians and 17 percent of   sniffles.
Americans experience
depression.
Seasonal Affective Disorder [SAD]
 ! Seasonal affective disorder is more than
   simply disliking winter.
 ! Seasonal affective disorder involves a recurring
   seasonal pattern of depression, usually during
   winter’s short, dark, cold days.
 ! Survey: “Have you cried today”? Result: More
   people answer “yes” in winter.
                       Percentage who cried
                         Men        Women
        August            4            7
        December          8            21
 Bipolar Disorder
! Bipolar disorder was once          Mania refers to a period of
  called “manic-depressive           hyper-elevated mood that is
  disorder.”                         euphoric, giddy, easily
! Bipolar disorder’s two polar       irritated, hyperactive,
  opposite moods are                 impulsive, overly optimistic,
  depression and mania.              and even grandiose.
                        Contrasting Symptoms
      Depressed mood: stuck          Mania: euphoric, giddy, easily
         feeling “down,” with:                irritated, with:
 !   exaggerated pessimism          ! exaggerated optimism
 !   social withdrawal              ! hypersociality and sexuality
 !   lack of felt pleasure          ! delight in everything
 !   inactivity and no initiative   ! impulsivity and overactivity
 !   difficulty focusing            ! racing thoughts; the mind
 !   fatigue and excessive desire     won’t settle down
     to sleep                       ! little desire for sleep
  Bipolar Disorder and Creative Success
Many famous and successful people have lived with
the ups and downs of bipolar disorder. Some
speculate that the depressive periods gave them
ideas, and the manic episodes gave them creative
energy. Any evidence of mood swings here?
Bipolar Disorder in Children and
Adolescents
! Does bipolar disorder
  show up before
  adulthood, and even
  before puberty?
! Many young people
  have cycles from
  depression to
  extended rage rather
  than mania.
! The DSM-5 has a new
  diagnosis for these
  kids: disruptive mood
  dysregulation
  disorder.
     Understanding Mood
          Disorders
Why are mood disorders so
pervasive, and more common
among the young, and especially
among women?
Why Does Depression Have
  so Many Symptoms?
          Understanding Mood
               Disorders
           Can we explain…
! why does depression often
  go away on its own?
! the course/development of
  reactive depression?
  Often, time heals a mood
  disorder, especially when
  the mood issue is in
  reaction to a stressful event.
  However, a significant
  proportion of people with
  major depressive disorder
  do not automatically or
  easily get better with time.
Suicide and Self-Injury
 ! Every year, 1 million people commit suicide,
   giving up on the process of trying to cope and
   improve their emotional well-being.
 ! This can happen when people feel frustrated,
   trapped, isolated, ineffective, and see no end to
   these feelings.
 ! Non-suicidal self-injury has other functions
   such as sending a message, or self-punishment.
Understanding Mood Disorders
                        Evolutionary
 Biological aspects
 and explanations         Genetic
                        Brain /Body
                      Negative thoughts and
  Social-cognitive       negative mood
   aspects and          Explanatory style
   explanations
                        The vicious cycle
An Evolutionary Perspective on
the Biology of Depression
! Depression, in its milder,
  non-disordered form, may
  have had survival value.
! Under stress, depression is
  social-emotional
  hibernation. It allows
  humans to:
   ! conserve energy.
   ! avoid conflicts and other
     risks.
   ! let go of unattainable
     goals.
   ! take time to contemplate.
Biology of Depression: Genetics
Evidence of genetic influence on depression:
1.DNA linkage analysis reveals depressed gene regions
2.twin/adoption heritability studies
Biology of Depression: The
Brain
! Brain activity is diminished in depression and
  increased in mania.
! Brain structure: smaller frontal lobes in depression and
  fewer axons in bipolar disorder
! Brain cell communication (neurotransmitters):
   ! more norepinephrine (arousing) in mania, less in
     depression
   ! reduced serotonin in depression
   Preventing or Reducing Depression:
    Using Knowledge of the Biology of
               Depression
1. Adjust
   neurotransmitters
   with medication.
2. Increase serotonin
   levels with exercise.
3. Reduce brain
   inflammation with a
   healthy diet
   (especially olive and
   fish oils).
4. Prevent excessive
   alcohol use .
 Understanding Mood Disorders: The Social-
          Cognitive Perspective
            Discounting positive
            information and assuming
            the worst about self,
  Low Self- situation, and the future Self-defeating
   Esteem                             beliefs such as
                                      assuming that
                            Learned   one (self) is
                         Helplessness unable to cope,
                                      improve,
                                      achieve, or be
 Depression is                        happy
associated with:
                                 Depressive
                                 Explanatory
                                    Style
Rumination
             Stuck focusing on
             what’s bad
    Depressive Explanatory Style
       How we analyze bad news predicts mood.
    Problematic event:
Assumptions about
   the problem
The problem is:
The problem is:
The problem is:
Mood/result that
goes along with
  these views:
  Depression’s Vicious Cycle
  A depressed mood may develop when a person
   with a negative outlook experiences repeated
                       stress.
The depressed
mood changes
a person’s
style of
thinking and
interacting in a
way that
makes
stressful
experience
more likely.
                   the mind is split from reality, e.g. a
                   split from one’s own thoughts so
Schizophrenia:     that they appear as hallucinations.
 Psychosis
  refers to a
 mental split                      Schizophrenia
 from reality                      symptoms
and rationality.                   include:
                                   !disorganized
                                   and/or delusional
                                   thinking.
                                   !disturbed
                                   perceptions.
                                   !inappropriate
                                   emotions and
                                   actions.
Positive and Negative
Symptoms of Schizophrenia
          Positive +                         Negative -
           presence of                       absence of
           problematic                         healthy
            behaviors                         behaviors
!   Hallucinations (illusory        !   Flat affect (no emotion
    perceptions), especially            showing in the face)
    auditory                        !   Reduced social interaction
!   Delusions (illusory beliefs),   !   Anhedonia (no feeling of
    especially persecutory              enjoyment)
!   Disorganized thought and        !   Avolition (less motivation,
    nonsensical speech                  initiative, focus on tasks)
!   Bizarre behaviors               !   Alogia (speaking less)
                                    !   Catatonia (moving less)
Schizophrenia Symptoms:
Problems in Thinking and Speaking
! Disorganized speech,
  including the “word                    ?!?!
  salad” of loosely
  associated phrases
! Delusions (illusory             ?!?!
  beliefs), often bizarre
  and not just mistaken;
  most common are
  delusions of grandeur
  and of persecution
! Problems with
  selective attention,
  difficulty filtering thoughts
  and choosing which
  thoughts to believe and
  to say out loud
Schizophrenia Symptoms:
Disturbed Perceptions                          You’re
                                       Am I     evil!
! People with schizophrenia
  often experience                     evil?
  hallucinations, that is,
  perceptual experiences not
  shared by others.
! The most common form of
  hallucination is hearing voices
  that no one else hears, often
  with upsetting (e.g. shaming)
  content.
! Hallucinations can also be
  visual, olfactory/smells, tactile/
  touch, or gustatory/taste.
Schizophrenia Symptoms:
Inappropriate Emotions
! Odd and socially inappropriate
  responses such as looking
  bored or amused while
  hearing of a death
! Flat affect: facial/body
  expression is “flat” with no
  visible emotional content
! Impaired perception of
  emotions, including not
  “reading” others’ intentions
  and feelings
Schizophrenia Symptoms:
Inappropriate Actions/Behavior
Odd and socially inappropriate
behavior can be caused by
symptoms such as:
!errors in social perception.
!disorganized, unfiltered thinking.
!delusions and hallucinations.
The schizophrenic body exhibits
symptoms such as:
!repetitive behaviors such as
rocking and rubbing.
!catatonia, such as sitting
motionless and unresponsive for
hours.
Onset and                          Course of
Development of                    Schizophrenia
                             Acute/Reactive
Schizophrenia                Schizophrenia In reaction to
                             stress, some people develop
! Onset: Typically,          positive symptoms such as
  schizophrenic symptoms     hallucinations.
  appear at the end of          – Recovery is likely.
  adolescence and in early   Chronic/Process
  adulthood, later for       Schizophrenia develops slowly, with
  women than for men.        more negative symptoms such as flat
! Prevalence: Nearly 1 in    affect and social withdrawal.
  100 people develop             – With treatment and support,
  schizophrenia, slightly           there may be periods of a
  more men than women.              normal life, but not a cure.
! Development: The               – Without treatment, this type of
  course of schizophrenia           schizophrenia often leads to
  can be acute/reactive or          poverty and social problems.
  chronic.
Subtypes of Schizophrenia
  Paranoid
  • Plagued by hallucinations, often with negative
    messages, and delusions, both grandiose and
    persecutory
  Disorganized
  • Primary symptoms are flat affect, incoherent
    speech, and random behavior
  Catatonic
  • Rarely initiating or controlling movement; copies
    others’ speech and actions
  Undifferentiated
  • Many varied symptoms
  Residual
  • Withdrawal continues after positive symptoms
    have disappeared
Understanding Schizophrenia
What’s going on              Abnormal brain
in the brain in               structure and
schizophrenia?                   activity
                  ! Too many dopamine/D4 receptors
                    help to explain paranoia and
                    hallucinations; it’s like taking
                    amphetamine overdoses all the time.
                  ! Poor coordination of neural firing in
                    the frontal lobes impairs judgment
                    and self-control.
                  ! The thalamus fires during
                    hallucinations as if real sensations
                    were being received.
                  ! There is general shrinking of many
                    brain areas and connections
                    between them.
Understanding Schizophrenia
                                      Schizophrenia is
Are there biological risk factors     more likely to develop
                                      in babies born:
affecting early development?
                                      !during and after flu
                                      epidemics.
                                      !in densely populated
 Biological Risk Factors              areas.
                                      !a few months after
Schizophrenia is somewhat more        flu season.
likely to develop when one or more of !after mothers had
these factors is present:             the flu during the
! low birth weight                    second trimester, or
! maternal diabetes                   had antibodies
! older paternal age                  showing viral
                                      infection.
! famine
! oxygen deprivation during delivery  !The lesson is to:
! maternal virus during mid-pregnancy       get flu shots
   impairing brain development             with early fall
                                           pregnancies.
Understanding Schizophrenia
Are there genetic risk
factors? If so, we would see
more similar schizophrenia       Genetic Factors
risk shared between              If one twin has
identical twins than fraternal   schizophrenia, the
twins (graph below). Do we?      chance of the other
                                 one also having it are
                                 much greater if the
                                 twins are identical.
                                 Having adoptive
                                 siblings (or parents)
                                 with schizophrenia
                                 does not increase the
                                 likelihood of
                                 developing
                                 schizophrenia.
 Understanding Schizophrenia
 Genetic and Prenatal Causes            ! Even if maternal flu
! Even in identical twins, genetics do    during the second
  not fully predict schizophrenia.        trimester doubles
                                          the risk of
! This could be because of                schizophrenia, this
  environmental differences.              means only 2
! First difference: twins in separate     percent of these
  placentas.                              babies develop the
                                          disorder.
                                        ! Genetics may
                                          differentiate these
                                          2 percent.
                                        ! Research shows
                                          many genes linked
                                          to schizophrenia,
                                          but it may take
                                          environmental
 Only one of two twins has the enlarged   factors to turn on
 ventricles seen in schizophrenia.        these genes.
Understanding Schizophrenia
Are there                      Social-
psychological               Psychological
causes?                        Factors
                ! Research does not support the
                  idea that social or psychological
                  factors (such as parenting) alone
                  can cause schizophrenia.
                ! However, there may be factors
                  such as stress that affect the
                  onset of schizophrenia.
                ! Until we find a mechanism of
                  causation, all we may have is a list
                  of factors which correlate with
                  increased risk.
     Predicting Schizophrenia:
        Early Warning Signs
   Social/psychological           Biological factors
   factors which tend to        which tend to appear
     appear before the           before the onset of
          onset of                 schizophrenia:
       schizophrenia:
! early separation from        ! having a mother with
  parents                        severe chronic
                                 schizophrenia
! short attention span
                               ! birth complications,
! disruptive OR withdrawn        including oxygen
  behavior                       deprivation and low
! emotional unpredictability     birth weight
! poor peer relations and/or   ! poor muscle
  solitary play                  coordination
        How common are
     psychological disorders?
Countries vary greatly in the percentage of people reporting
mental health issues in the past year.
  Rates of
Psychological
  Disorders
This list takes a closer
look at the past-year
prevalence of various
mental health diagnoses in
the United States.
Risks and Protective Factors for
       Mental Disorders
           Who is at risk of mental disorders?
             Who is less at risk?
  Outcomes for People with
  Psychological Disorders
There are risks to be watchful of,
obstacles to be overcome, and
improvements to be made, often with
the help of with treatment.
!Some people with psychological
disorders do not recover.
!Some achieve greatness, even with a
psychological disorder.