CLINICAL RESEARCH
Evidence-based concepts and
         procedures for bonded inlays
         and onlays. Part II. Guidelines for
         cavity preparation and restoration
         fabrication
         Giovanni Tommaso Rocca, DMD
         Senior lecturer, Division of Cariology and Endodontology,
         University Clinic of Dental Medicine, Geneva, Switzerland
         Nicolas Rizcalla, DMD
         Senior lecturer, Division of Cariology and Endodontology,
         University Clinic of Dental Medicine, Geneva, Switzerland
         Ivo Krejci, Prof, DMD,PD
         President, University Clinic of Dental Medicine, Geneva, Switzerland
         Director, Department of Preventive Dental Medicine and Primary Dental Care,
         Head, Division of Cariology and Endodontology,
         University Clinic of Dental Medicine, Geneva, Switzerland
         Didier Dietschi, DMD, PhD, PD
         Senior lecturer. Division of Cariology and Endodontology,
         University Clinic of Dental Medicine, Geneva, Switzerland
         Adjunct Professor, Department of Comprehensive Dentistry,
         Case Western University, Cleveland, Ohio
         Private Education Center, The Geneva Smile Center, Geneva, Switzerland
         Correspondence to: Giovanni Tommaso Rocca, DMD
         School of Dentistry, Faculty of Medicine, University of Geneva, 19 rue Barthélémy-Menn, 1205 Geneva, Switzerland;
         E-mail:giovanni.rocca@unige.ch
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Abstract                                      after a multifactorial analysis, which in-
                                              cludes cavity dimensions and the result-
The second part of this article series pre-   ing tooth biomechanical status, as well
sents an evidence-based update of clin-       as occlusal and esthetic factors. The clin-
ical protocols and procedures for cavity      ical impact of the modern treatment con-
preparation and restoration selection for     cepts that were outlined in the previous
bonded inlays and onlays. More than           article – Dual Bonding (DB)/Immediate
ever, tissue conservation dictates prep-      Dentin Sealing (IDS), Cavity Design Op-
aration concepts, even though some            timization (CDO), and Cervical Margins
minimal dimensions still have to be con-      Relocation (CMR) – are described in de-
sidered for all restorative materials. In     tail in this article and discussed in light of
cases of severe bruxism or tooth fra-         existing clinical and scientific evidence
gilization, CAD/CAM composite resins          for simpler, more predictable, and more
or pressed CAD/CAM lithium disilicate         durable results. Despite the wide choice
glass ceramics are often recommend-           of restorative materials (composite resin
ed, although this choice relies mainly on     or ceramic) and techniques (classical or
scarce in vitro research as there is still    CAD/CAM), the cavity for an indirect res-
a lack of medium- to long-term clinical       toration should meet five objective cri-
evidence. The decision about whether          teria before the impression.
or not to cover a cusp can only be made       (Int J Esthet Dent 2015;10:392–413)
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         Introduction                                    has the potential to resolve most of the
                                                         clinical difficulties usually encountered
         The first part of this series of articles was   during the preparation, isolation, impres-
         presented as a comprehensive, revised           sion taking, and cementation of tooth-
         treatment rationale and as clinical pro-        colored inlays and onlays, while improv-
         cedures for bonded inlays and onlays,           ing treatment quality and longevity.
         based on scientific and long-term clin-
         ical evidence. The most relevant princi-
         ples reported were the absence of tissue        Occlusal considerations
         removal following materials’ properties
                                                         and tooth preparation
         or technical requirements, and the ef-
         fective preparation of dental tissues fol-      Restoration material choice
         lowing Dual Bonding (DB)/Immediate
         Dentin Sealing (IDS) concepts,1-8 Cav-          Regarding the restorative material used
         ity Design Optimization (CDO), and Cer-         for inlays and onlays, ceramics (pressed
         vical Margins Relocation (CMR),                 or fired) were traditionally preferred, as
         depending on the clinical situation and         they were thought to be stronger and
         needs. The aforementioned procedures            more reliable than their composite coun-
         aim to avoid any additional tooth prep-         terpart. However, the referred literature
         aration and tissue removal required to          never clearly confirms the advantage of
         create the geometry for indirect pos-           ceramics, especially taking into consid-
         terior restorations and to protect the          eration disparate testing environments
         pulpodentinal structures from any con-          for both restorative materials.14-16 Ac-
         tamination/disturbance during the tem-          tually, the patient selection and clinic-
         porary phase, as well as to stabilize and       al environment were manifestly more
         improve the adhesive interface quality.         favorable to ceramic restorations, as
         When needed, the CMR technique (also            indirect ceramic restorations were nei-
         known as Deep Margin Elevation – DME)           ther placed in social clinics nor in pa-
         helps to raise deep cervical margins to a       tients with severe bruxism, while such
         visible and accessible level (supragingi-       restrictions did not normally apply (or
         vally), easing impression and cementa-          did not apply as strictly) to composite
         tion procedures. Moreover, due to an            studies. Despite this, composite resins
         even cavity design, the CDO and CMR             have been widely used for the fabrica-
         techniques facilitate the placement of          tion of inlays and onlays due to a simpler
         temporary restorations (non-cemented)           manufacturing process (and thus lower
         and the restoration fabrication. Regard-        cost), as well as their excellent esthet-
         ing cementation, the use of a highly            ics and easier reparability. A more “re-
         filled, light-curing restorative material is    cent” and increasingly used alternative
         recommended instead of a dual-curing            is CAD/CAM restoration, made in either
         composite cement because of its super-          ceramic or composite resin blocks (ie,
         ior mechanical properties and wear re-          IPS Empress or e.max CAD, Ivoclar
         sistance, as well as its practicality.
         Overall, this updated clinical protocol         this large choice with regard to materials
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                                                                     ROCCA ET AL
and fabrication methods, the tooth prep-       ment of the in vivo performance of new
aration for all kinds of modern bonded         monolithic ceramic restorations in a criti-
restorations relies on similar specific        cal biomechanical environment.
principles, which differ from those for
traditional cast-gold inlays and onlays,       Preparation extent and restoration
and even the first generation of fired         thickness
porcelain restorations, whose limited
mechanical resistance imposes more             All tooth-colored materials (composite
demanding and invasive preparations.           resin or ceramic) used for the fabrica-
  The occlusal environment has to be           tion of posterior indirect restorations are
evaluated, as it plays an important role       submitted to high occlusal functional
in restoration longevity and can also          stresses; consequently, their inherent
influence   material   choice.   Extensive     vulnerability needs to be compensated
restorations with generally large and          for by restoration thickness and proper
deep cavities (mainly non-vital teeth)         adhesive cementation. Although the res-
in high load-bearing areas (especially         torations should therefore be as thick as
the second molars) associated with an          possible, this approach is tempered by
unfavorable occlusal context (such as          the fundamental principles of minimal
patients with bruxism) have to be con-         invasiveness.29 Moreover, an unconsid-
sidered biomechanically vulnerable and         ered sacrifice of enamel and dentin could
more susceptible to failure. In the latter     also directly weaken the tooth. For exam-
unfavorable situation, only the strong-        ple, Fennis and co-workers have dem-
est materials should be chosen, based          onstrated that thick overlay restorations
mainly on their superior mechanical            show higher static fracture strength com-
properties. Today, new CAD/CAM com-            pared to conservative ones,      although
posite resin blocks (ie, Lava Ultimate,        they present more drastic and irrevers-
                                               ible failures; ie, thicker restorations may
based restorations (ie, IPS e.max Press        be stronger but simultaneously imply
or CAD, Ivoclar Vivadent) are preferred,       thinner and weaker dental tissues under-
the former option having some interest-        neath them. At the same time, extremely
ing stress-absorbing   properties,17   while   thin material is not systematically and un-
requiring simpler procedures when a            conditionally recommended. If one takes
surface modification or repair is need-        into consideration that a few tenths of a
ed.18 Recent in vitro studies on the frac-     millimeter can considerably strengthen a
ture and fatigue resistance of direct and      restoration, the best compromise would
indirect restorations of a severely eroded     be between material resistance and the
tooth model demonstrated the favorable         clinical situation.    We should therefore
behavior of CAD/CAM composite ma-              move away from the blind application of
terials.17,19-24 Apart from the non-vital      “minimally invasive dentistry” to a more
tooth configuration, the aforementioned        realistic concept of “minimally hazard-
findings are well supported by clinical        ous dentistry”, which is particularly per-
trials.25-28 However, less information is      tinent to large and deep cavities and to
available to date regarding the assess-        non-vital teeth.
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                                                                  ials, including composite resins, pressed
                                                                  ceramics, and CAD/CAM blocks (apart
                                                                  from traditional feldspathic and leucite-
                                                                  reinforced ceramics), while the stabil-
                                                                  ity and impact of thinner material lay-
                                                                  ers on restoration longevity is still under
                                                                  evaluation. Moreover, it is important to
                                                                  note that minimal material thicknesses
                                                                  should be limited to monolithic/mono-
                                                                  laminar restorations, as a layering pro-
                                                                  cedure could mean including imperfec-
         Fig 1   Oscillating selectively coated diamond in-       tions in the narrow available space, thus
         struments for the finishing of the interproximal zone.
                                                                  weakening the system. Finally, esthetic
                                                                  considerations will also have an impact
                                                                  on restoration thickness (see “Esthetic
                                                                  considerations” below).
                                                                    In conclusion, a good compromise
                                                                  between tissue preservation and a suita-
            The minimal occlusal thickness al-                    ble restoration thickness has to be found
         lowed for a material depends on its in-                  and adapted to each case or tooth-spe-
         trinsic mechanical features (static and                  cific occlusal and esthetic context.
         dynamic reaction to stresses) and is
         therefore material- and even brand-                      Clinical guidelines
         dependent. Thus, usual recommenda-
         tions based on clinical experience and                   It follows, then, that while the cavity de-
         in vitro testing suggest to attain at least              sign and extent is largely dictated by
         1 mm thickness for composite resins,                     conservation principles, together with
         and 2 mm for low-strength ceramics,                      occlusal and esthetic parameters, the
         such as feldspathic (eg, Vita Mark II,                   overall cavity design is related to the
         Vita) and leucite-reinforced (IPS Em-                    pathology and presence of decayed tis-
         press I, Ivoclar Vivadent) ceramics.                     sues rather than the need for macrore-
         For new lithium disilicate-reinforced ce-                tention or friction.
         ramics (ie, IPS e.max Press or CAD),                       Practically, preparation starts with the
         the minimal recommended thickness                        removal of the existing restoration and
         seems to be closer to that recommend-                    decayed tissues without initially finishing
         ed for composite resin, ie, between 1                    the enamel margins. In less accessible
         and 1.2 mm.                    The presence of           areas (usually interproximally), oscillat-
         enamel under these thin ceramic res-                     ing, selectively diamond-coated instru-
         torations has also been recently proven                  ments (ie, PCS, EMS or Sonicsys, KaVo)
         to yield a certain positive effect.                      facilitate the preparation and finishing
         Overall, a restoration thickness between                 of cavities (Fig 1). When cavity margins
         1.0 and 1.5 mm seems to be advisable                     violate the biological width, a crown-
         for all modern “white” restorative mater-                lengthening procedure may be needed,
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while for subgingival/intracrevicular cer-    to follow aforementioned conservation
vical margins (a more frequent condi-         principles, thin and undermined cavity
tion), a conservative CMR is advised.         walls can be maintained and reinforced
The decision to use a specific technique      with composite resin during the adhe-
depends less on ultra-strict biological       sive resin lining of the cavity. The au-
width considerations and more on the          thors recommend a minimum of 1 mm
future accessibility of the margins to se-    as minimal wall width/thickness before
cure the clean and dry environment nec-       reinforcement. In cases where the mini-
essary for proper adhesive techniques.        mal residual thickness is below this
Fissures (in dentin or enamel) should         measurement, cusp coverage is indi-
ideally be included in the preparation,       cated (this guideline seems to be the
considering potential bacterial leakage       accepted general clinical consensus
or structural weakening, although their       nowadays). The aim is to have a more
extension in inaccessible zones often         homogeneous biting force distribution
prevents these flaws from being fully         and offer a “protective effect” for the un-
eliminated.                                   derlying weakened tooth structure. The
                                              resulting “invasiveness” could, howev-
Thin cavity walls and occlusal                er, increase the risk of irreversible tooth
                                              fracture   (below   the   cementoenamel
coverage
                                              junction – CEJ), as is shown in vitro by
Little is known scientifically about the      Fennis et al,   although such clinical ob-
minimal thickness needed to maintain          servation is extremely rare in vital teeth.
thin tooth walls and what is to be con-       Finally, the systematic occlusal cover-
sidered totally safe and conservable,         age of functional and/or non-function-
knowing that a multitude of parameters        al cusps is not yet advocated, as it is
will impact such a decision process. The      seemingly not proven to increase the
presence of thin walls around an exten-       final strength of the tooth-restoration
sive cavity is, in any case, considered a     system, both for composite resins40 and
strong indication for indirect restorations   ceramics.41-44
rather than direct fillings, as polymeriza-     In conclusion, occlusal coverage is
tion might deform the remaining facial        recommended for cavity walls of 1 mm
and lingual tooth structures, potentially     or thinner, while for “intermediate” thick-
inducing cracks due to the inward cusp        ness (1 to 2 mm), the occlusal context
movement that follows.         The cavity     including tooth position, presence of
size and design (C-factor), as much as        parafunctions, and the kind of lateral
the stratification technique, will impact     guidance (canine or group guidance)
such stresses on residual tooth struc-        should be taken into account when mak-
ture.   This is why indirect techniques       ing the therapeutic decision. The cavity
are generally preferred, because poly-        configuration, and in particular the pres-
merization shrinkage is confined to the       ence or absence of the marginal ridges,
thin layer of luting resin cement.            can also play a role in the final strength
  Different options are available with an     of the residual walls, especially in endo-
indirect approach. First, in an attempt       dontically treated teeth.45
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         Fig 2   The “smile space” of two different patients. The visibility of the treated tooth during smile has to be
         verified before cavity preparation. The patient’s lips can act as a curtain behind which the tooth–restoration
         transition can be hidden.
         Esthetic considerations                                 esthetic zone is generally unknown. As
                                                                 the removal of undermined, fissured or
         For restorations extending into the buc-                thin buccal cusps could bring the res-
         cal-esthetic zone (the virtual space be-                toration into a visible and more critical
         tween the upper and lower lips during                   esthetic zone, this occurrence must be
         full smile), margin positioning plays an                taken into account and a shade selec-
         important role (Fig 2). Actually, the sim-              tion systematically performed before the
         plest and most ideal situation is for the               preparation. Otherwise, tissue dehydra-
         restoration margins to be located in the                tion will prevent the clinician from later
         incisal or cervical thirds. In both situa-              choosing a precise and reliable shade
         tions, a good esthetic integration of the               registration because it only takes a few
         restoration can easily be achieved due                  seconds of tissue dehydration to impact
         to a simpler tissue arrangement; practi-                shade perception.
         cally, almost only one tissue is present
         – enamel in the incisal third, and dentin               Shade selection
         in the cervical third. This makes the es-
         thetic integration of the restoration tech-             Additionally, metallic and temporary res-
         nically and optically more predictable                  torations, caries, and – in general – any
                                                                 discolored, decayed tissue may alter
         low, margins can be left elsewhere on                   dentin and enamel shades; thus, they
         the buccal cusp, depending only on the                  should be removed beforehand under
         restorative needs.                                      water spray, to preserve tissue hydra-
            While the esthetic impact of the res-                tion. As an alternative, tooth shade can
         toration should theoretically be analyzed               be recorded and crossed-matched with
         before the cavity preparation, the final                a non-restored, contralateral or neigh-
         extent of the restoration in the buccal-                boring tooth.
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