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Preparation of Aloevera Gel

Article in International Journal of Advanced Research in Science Communication and Technology · August 2022
DOI: 10.48175/IJARSCT-5930

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 ISSN (Online) 2581-9429
IJARSCT
International Journal of Advanced Research in Science, Communication and Technology (IJARSCT)

Volume 2, Issue 1, August 2022

Impact Factor: 6.252

Preparation of Aloevera Gel

Mr. Sachin Navale*, Ms. Tejaswini Shinge, Ms. Sonali Mali,
Ms. Apeksha Jadhav, Ms. Poonam Shinde, Ms. Pratiksha Narute,
Nootan College of Pharmacy, Sangli, Maharashtra, India

Abstract: Aloe vera, commonly known as Barbados or Curaçao Aloe, is an herbal medicine with a long
tradition of use by a variety of cultures. The succulent plant grows in arid and subtropical climates and is
best known for 2 distinct preparations: the clear mucilaginous gel that is widely used for the treatment of
minor burns, especially sunburns, and the thick sap of the leaves that turns yellow-brown and has strong
laxative effects that caution its use. The traditional uses of the clear mucilaginous gel are manifold, ranging
from topical applications to reduce perspiration to oral dosing for diabetes and a range of gastrointestinal
ailments. The efficacy of aloe vera gel to treat burn wounds, genital herpes, and seborrheic dermatitis have
been shown in clinical trials, but other indications such as psoriasis or internal application for the
treatment of type 2 diabetes remain inconclusive. The main limitation of the current clinical knowledge
about aloe vera gel is small clinical studies that often lack rigorous methodology. Several clinical trials are
being conducted to further evaluate the use of aloe vera gel for a variety of disorders, as well as to further
confirm traditional uses of the plant extract.

Keywords: Aloe vera, health and beauty, skin.

I. INTRODUCTION
Aloe vera gel is used as an ethnomedicine in Trinidad and Tobago for hypertension. The most common folk use of aloe
has been for the treatment of burn wounds and specifically to aid in the healing process, reduce inflammation, and
tissue scaring. The gel was described by Dioscorides and used to treat wounds and mouth infections, soothe itching,
and cure sores. The use of aloe vera gel as a household remedy in the United States was triggered by reports of its
beneficial effect on radiation dermatitis followed by a boom in cultivation in the 1930s; it remains a common plant and
for burns and abrasions. Important contemporary uses of the gel exist in traditional medicines of India, China, and
Mexico, as well as Middle America and the West Indies. Mexico is producing roughly 47% of aloe worldwide with a
total sales volume of $123.5 million US dollars as of 2008.6
Despite its widespread popularity, scientific evidence on the aloe vera gel remains sparse. Aloe vera gel is regarded as
safe if applied topical with only a few allergic reactions being reported.7 The efficacy of aloe vera gel to treat burn
wounds, genital herpes, and seborrheic dermatitis have been shown in clinical trials, but other indications such as
psoriasis or internal application for the treatment of type 2 diabetes remain inconclusive. The major application of aloe
vera gel remains as a skin moisturizer in cosmetics and as an après treatment for sunburns, for which it has proven its
effectiveness.

II. DESCRIPTION
Aloe vera is a succulent plant with thick, fleshy, serrated, lanceolate-shaped leaves of green-greyish color. Aloe vera
inner gel is obtained from the lower leaves of the plant by slicing the leaf open. The gel is clear, odorless, and tasteless
and should be free of leaf skin or yellow parts. No consistent standardization has been established, but the International
Aloe Science Council (IASC), a trade association of internationally based aloe producers and marketers, requires
adherence to certain specifications for the product to be certified.Other preparations include a hydrophilic cream
containing 0.5% aloe vera gel and an emulsion consisting of 30% aloe vera

2.1 Ingredients
Aleovera juice , methyl parabin, carbapol 934,glycerin, sandalwood oil , rose water, triethalamine.

Copyright to IJARSCT DOI: 10.48175/IJARSCT-5930 105

www.ijarsct.co.in
 ISSN (Online) 2581-9429
IJARSCT
International Journal of Advanced Research in Science, Communication and Technology (IJARSCT)

Volume 2, Issue 1, August 2022

Impact Factor: 6.252
2.2 Procedure
1. Take a fresh aloevera juice in a beaker heat it for 2 to 3 min. Then keep it aside for cooling.
2. At the same take another beaker take 0.01 gm methyl paraben and add into 15 ml of purified water. Mix it well
and keep this solution for water bath stir it properly.
3. After dissolving the methyl parabin keep it aside for cooling. After cooling add carbopol 934 and stir it by
using magnetic stirrer.
4. Take 35 ml aloevera juice and add into the methyl paraben. Mix it well.
5. After that add a glycerin and sandalwood oil as a flavoring agent.
6. Add a colouring agent. After that add a triethanolamine as a gelling agent. Stir it properly..the liquid is gets
converts into gel. And aloevera gel is prepared.

2.3 Mechanism of Action

1. Effects on skin exposure to UV and gamma radiation: Aloe vera gel has been reported to have a protective
effect against radiation damage to the skin.
2. Moisturizing and anti-aging effect: Mucopolysaccharides help in binding moisture into the skin. Aloe
stimulates fibroblast which produces the collagen and elastin fibers making the skin more elastic and less
wrinkle
3. Antiseptic effect: Aloe vera contains 6 antiseptic agents: Lupeol, salicylic acid, urea nitrogen, cinnamonic
acid, phenols and sulfur. They all have inhibitory action on fungi, bacteria and viruses.
4. Healing properties: Aloe gel not only increased collagen content of the wound but also changed collagen
composition (more type III) and increased the degree of collagen cross linking. Due to this, it accelerated
wound contraction and increased the breaking strength of resulting scar tissue.

2.4 Uses
 Mild to moderate burnsas well as erythema
 Genital herpes
 Seborrheic dermatitis
 Adjunct therapy of spontaneous fibrosarcomas (determined by clinical trials and/or official monographs and/or
empirical use)
 Psoriasis vulgaris
 Skin moisturizer
 Type 2 diabetes
 Malignancies and immunodeficiency viruses in cats
 Oral lichen planus infections
 Angina pectoris
 Ulcerative colitis
 UV-induced erythema14 Kidney stones
 Alveolar osteitis.

2.5 Adverse Effects

 Hypersensitivity reactions
 Allergic reactions

III. CONCLUSION
In this project we can prepred the aleovera gel and study their preparation. Uses , their action , adverse drug effects. It
seems that the application of Aloevera, as a complementary treatment along with current method, can improve wound
healing and promote the health. Prmosinglyit may also provide other health benefits, largely due to its antioxidants
property.

Copyright to IJARSCT DOI: 10.48175/IJARSCT-5930 106

www.ijarsct.co.in
 ISSN (Online) 2581-9429
IJARSCT
International Journal of Advanced Research in Science, Communication and Technology (IJARSCT)

Volume 2, Issue 1, August 2022

Impact Factor: 6.252
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parenchyma gel. J Ethnopharmacol.
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Roentgenology.
[5]. Halles JS. A drug for all seasons. Medical and pharmacological history of aloe. Bull N Y Acad Med.
[6]. Rodriguez S. How Large is the Aloe Market. [PowerPoint presentation]. 2008.
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