No Authors Country Objective Design Participant Treatment Dosing Measurement Result

Components
1 Bashirian, et al. Iran The effects of an A randomized There are 94 male Educational Five-week Multi-theory There is not
(2019). educational controlled trial. adolescent intervention training model clear evidence
intervention students (grades sessions. (45 (MTM) for WPS
based on 10, 11) smoked min for 1 questionnaire cessation in the
MTM on water pipe (WP) week) program
reducing WPS in the past month
among male The mean age of
adolescent the participants
students. was 16.73 (±.642)
yr.
2 Jordan To test the A cluster- 213 male students -the Triple A in 4 months post Self- Students from
Al-sheyab, et effectiveness of a randomized Jordan (TAJ- intervention. Administered the intervention
al. (2016) school-based, controlled tria Plus schools) group reported
peer-led smoking Nicotine significant
and asthma Dependence improvements in
education Scale smoking related
knowledge and
program perception and
lower nicotine
dependence as
compared to the
comparison
group.

3 Fritz, et al. America This study A pretest- 121 high school Computerized 30-minute a questionnaire CASCP
evaluated a posttest quazi students who Adolescent computerized with five increased the
computerized experimental completed self- Smoking sessions subsets aimed at number of quit
intervention design reported Cessation determining attempts. At 1
designed to assist questionnaires Program smoking month after the
high school-aged (CASCP dependence, intervention,
smokers to stage of change, 20% of the
consider self-efficacy experimental
 not smoking and or the belief that group quit
move forward in quitting was smoking
the "Stages of possible, and
Change." social support. CASCP was
found to be an
effective and
inexpensive
intervention that
motivates
adolescent
smokers to
consider
smoking
cessation, move
forward in the
stage of change,
and decrease
nicotine
dependence.
4 Krist, et al. Germany to evaluate the Three-armed 2801 students in smoking Trained self-reported A combined
(2016). long-term cluster- seventh grade prevention moderators regular smoking. student–parent
effectiveness of a randomized students aged 11– training course. lead through smoking
combined controlled trial 16 years. Included the programme prevention
student–parent (RCT) 47 schools, 161 and answer intervention
and a student- classes. questions. delivered via
only smoking Overall, secondary
prevention completion schools in
programme to takes Berlin, Germany
reduce the approximately did not result in
smoking 2 hours. a statistically
prevalence among significant
7th grade students reduction in
regular smoking
compared with a
control group or
 a student-only
intervention.
5 Blank et al. United State Examined A randomized Out of a total of N-O-T (N = 6 Those in the Not exaxtly - The result
participant controlled trial 232 youth who schools), N- N-O-T and N- mention the name shows that
characteristics as participated at OT+ O-T+FIT of questionnaire, there is
moderators of baseline, FIT (N = 7 conditions also but the researcher reduction in
adolescents’ (These baseline schools), or BI received 10 ask free response teenager
smoking and follow-up (N = 6 schools). weekly questions smoker who
cessation samples sessions with Accordingly, get N-O-T
outcomes as a (N = 232 vs 114)) the ALA- respondents were intervention
function of trained asked 2 free- and N-O-T
intervention: Not- facilitator to response + Fit, but
on-Tobacco cover topics questions: (1) there are no
(N-O-T), N-O-T such as stress “How many significant
with a physical management, cigarettes do you result in
activity dealing with smoke A DAY on teenager
(PA) module (N- family/peer a typical with BI
O-T+FIT), or pressure, and WEEKDAY intervention
Brief Intervention promotion (such as Monday - The
(BI). of a healthy or Tuesday)?” teenager
lifestyle and (2) “How who get N-
many cigarettes O-T+ Fit
do you smoke A intervention
DAY on a typical shows that
WEEKEND day increasingly
(such as in physical
Saturday)?” activity and
lower
Physical activity smoking.
(PA). PA was - The
originally teenager
assessed motivation
within the intrinsic
intervention moderate to
 conditions high and get
through N-O-T+ Fit
3 questions that has a
addressed reducing
“moderate,” frequency in
“vigorous,” smoking.
and “moderate +
vigorous”
activity.9
6 Perry (2009) India To assess the A randomized 14063 students Project MYTRI Over Two Not telling the students in the
effectiveness of a controlled trial. {Mobilizing consecutive name of intervention
2-year Youth for academic years instrument of group were
multicomponent. Tobaeco- interventions meassurement. significantly less
likely than were
school-based Reiated students in the
intervention Initiatives in control group to
designed to India) They use kinds of
questionnaire exhibit increases
reduce tobacco in cigarette
use rates amonc) that’ s ask to
students: “during smoking or bidi
adolescents smoking over
the last 30 days,
did you smoke 1 the 2-vear study
or more?” period. They
were also less
likely to intend
to smoke or
chew tobacco in
the future
7 Guilamo- United evaluated the A total of 1386 All adolescents TNT involves completed self- Including parent
Ramos, et al States effectiveness of a dyads (80% of received a a 10-day administered add-on
(2010). parent-based add- those contacted) version of classroom- surveys components in
on component attended the event Project Towards based school-based
to a school-based and participated No Tobacco curriculum, smoking
intervention to in Use (TNT with each prevention
prevent cigarette the study lesson lasting programs can
 smoking among approximately reduce smoking
African 45 minutes. A behavior on the
American and 2-lesson part of inner-city
Latino middle booster session middle school
school youths. is also youths
available.

The modified
version of TNT
was conducted
over 2 face-to-
face sessions,
each lasting
approximately
2.5 hours and
delivered on
separate
days (primarily
in the evenings
and on
weekends).
8 Chan, et al. Hong Kong to evaluate the Cluster, 831 Chinese adult - 12-page Socio- Brief on-site
(2017) effectiveness of a parallel RCT smokers who self-help demographic advice by
brief smoking (with were recruited in smoking characteristics, trained youth
cessation advice allocation ratio public areas cessation smoking and counselors had a
delivered by of 1:1) booklet. quitting history, modest effect on
briefly-trained - Brief intention to quit, smoking
youth counselors (about 5 perceived cessation, but
at the enrolment min) importance, the effect was
of an incentive- counseling difficulty, and not significant.
based smoking using confidence to quit
cessation AWAR smoking. All
campaign protocol these
including characteristics
(1) Ask the were assessed by
 smoking self-report
history, (2)
Warn about
the high
risk (i.e.,
half of the
smokers
will die of
smoking-
related
diseases),
(3) Advise
to quit, and
(4) Provide
the contact
information
of publicly
available
smoking
cessation
services
9 Gao et al. America To know the A clinical trial 15 high school Virtual Reality Following Presence and The total
effect of Virtual one group students Teen completion of Realism questionnaire
Reality Teen pretest post the game or the Questionnaire score decreased
test passing of (PRQ) after the
thirty minutes, participants
whichever Post-Exposure played the game,
came Simulator indicating that
first, the Sickness they understood
participants Questionnaire the negative
were invited to (PESSQ) habits associated
take the Post- with smoking
Questionnaire, and decided to
PRQ, and the spend less effort
PESSQ. in activities
 which
increase their
smoking
cravings
10 Peterson et al. USA To examines for A randomized 2151 teen (high Motivational Follow-up Not telling the No evidence of
(2016) the first time controlled trial. schools) smokers Interviewing until 7 years name of intervention
whether such and Cognitive after passing instrument of impact at seven
positive early Behavioral from high meassurement. years post high
effects from teen Skills Training schools. school was
smoking telephone They used observed for the
cessation counseling telephon to main endpoint of
intervention. evaluate the six-year
intervention can effect of prolonged
endure into young intervention. abstinence
adulthood in the neither among
absence of all smokers, nor
additional among the
intervention subgroups of
daily smokers
and less-than-
daily smokers,
nor among other
a priori
subgroups. But,
observed among
males was some
evidence of an
intervention
impact on two
endpoints related
to progress
towards quitting:
reduction in
number of days
smoked in the
 past month, and
increase in the
length of the
longest quit
attempt in the
past year.
11 Castro,et al. Switzerland The aim of this Cluster RCT 1471 students MobileCoach Throughout the Participants took The majority of
(2017) study was to from 360 Tobacco (MCT) 3-month part in a Web- tobacco-
determine Swiss vocational if intervention based health smoking
adolescents’ school classes survey during a adolescents
trajectories of participated in regular class engaged
engagement with this study session, by which extensively with
a mobile phone– data on potential a mobile phone–
delivered predictors of based smoking
smoking engagement and cessation
cessation program outcome program.
over time and the variables were
associations these collected.
trajectories have
with baseline
characteristics
and treatment
outcomes
12 Hong, et al. Taiwan To examine the A mixed 66 participants at Art therapy baseline - There is no
(2018) effects of art method of two schools and interventions. characteristics, clear
therapy on qualitative and aged 16–20 years the four- evidence for
smoking quantitative who had smoked dimensional smoking
cessation in rural approaches for at least two Adolescents’ cessation in
Taiwanese youth using pre-test, years. Need for the art
smokers. post-test, and Smoking Scale therapy
follow- up (ANSS), the intervention
questionnaires Fagerstrom Test program.
for Nicotine - But the
Dependence combined
 (FTND), smoking results in the
cessation self- current
efficacy (SCSE), mixed-
and the design study
Rosenberg Self- suggest that
esteem Scale art therapy
(RSES). classes
should
continue in
regular
school
classes to
motivate
youths to
cease
smoking
through
drawing and
art
13 Espada et al. Spanyol a randomized 1,546 Spanish Project EX involves eight Assessment-day Compared to the
controlled trial students sessions smoking behavior standard care
delivered in was assessed with control
classrooms the item asking condition, the
over a 6-week “Did you smoke program
period. The tobacco today?” condition
first four The level of revealed a
sessions are nicotine greater reduction
held in a 2- dependence was in smoking
week period. assessed intentions and
The second with the 8-item CO ppm levels.
four sessions modified
are held once Fagerstrom
per week Tolerance
during the Questionnaire
following (mFTQ)
 month.
To assess
smoking
intention,
students were
assessed with the
question, “Do
you think you
will ever quit
smoking
cigarettes?,”
with response
categories being
0: I never smoke
cigarettes, 1: Yes,
I already have, 2:
Yes, I will
sometime in the
future, 3: Yes, I
will in the next
few weeks, 4:
Maybe, and 5: No
14 Gonzalvez et al. Spain To test the A randomized 1,546 Spanish The Project EX Over 6 weeks They used self- Compared to the
(2017) effectiveness of sudents classroom period of report, closed- control
Project EX controlled trial. curriculum intervention ended and fill-in- condition, the
classroom-based and the-blank program
smoking to response condition
prevention Two years questionnaire, revealed a
follow-up to which was greater reduction
and smoking see the administered over in nicotine
cessation. outcome. a one class period dependence,
to evaluate smoking
outcome. intention, and in
the number of
Smoking cigarettes
 behavior was smoked during
assessed with the the previous
fill-in-the blank month. The CO
item asking monitor repeated
“How many assessments
cigarettes have revealed a
you smoked in significant
the last month decrease of ppm
(30 days)?” levels in the
program group.
The level of Intent to treat
nicotine quit rates were
dependence was 14.28 and 0%,
assessed with the respectively, for
8-item modified the program and
Fagerstrom control
Tolerance conditions.
Questionnaire
(mFTQ)
15 Shi,et al. (2013) Chinese evaluated the cluster In total, 122 mobile phone Smoking self-perceived owned a mobile
effectiveness of a randomization participants text-messaging behaviour was usability of phone
mobile phone based smoking measured by smoking with text-
text-messaging cessation asking cessation messaging
based smoking intervention participants measures was function, had
cessation to report the surveyed in all access to the
intervention number of participants by Internet,
package among cigarettes they questionnaire. self-reported
Chinese smoked in the smoking at least
adolescent previous 7 1 cigarette per
smokers days and 30 week and a
days, and the duration of
circumstances smoking of at
of least 12 weeks
smoking such
as when, where
 and with
whom.
16 McCambridge, London A cluster 416 students aged Motivational Both - Nicotine This particular
et al. (2010) To test the randomised 16-19 years old Interviewing interventions dependence adaptation of MI
effectiveness of trial recruited in 12 (MI) were scheduled was is ineffective as
adaptation of London Further individualised for delivery measured a universal drug
Motivational Education intervention and during a one- with the prevention
Interviewing (MI) colleges without Drug hour lesson. Fagerstrom intervention and
for universal regard to Awareness scale; does not merit
prevention substance use (DA) control - Cannabis further study.
purposes (e.g status intervention. dependence
prevention of with the
tobacco, alcohol Severity of
and other drug Dependence
use, particularly Scale (SDS);
amongst the - Hazardous
young). drinking with
the Alcohol
Use Disorder
Identification
Test
(AUDIT)
17 Cassidy,et al America The aim of this Experimental A total of 195 Nicotine The four doses Tobacco Use All four nicotine
(2018) study was to design, adolescents were content proof tested in the History cigarette types
investigate the phone screened current study Questionnaire significantly
effects of varying and 120 (61.5%) contained 15.8, reduced
nicotine content were eligible. Of 5.2, 1.3 and Before and after abstinence-
PROOF in these, 88 0.4mg of smoking, nicotine induced craving,
cigarettes participants nicotine per withdrawal withdrawal, and
(73%) completed gram of symptoms were negative affect
an in-person tobacco, and measured using
on: (1) screening/baselin all tar yields the Minnesota
abstinence- e session. Of were 9±1.5mg. Nicotine
induced these 88, 55 were These Withdrawal Scale
withdrawal confirmed eligible correspond to
 symptoms, (62.5%). Of the roughly 0.8mg,
craving, and 55 participants 0.26mg,
negative affect; who were eligible 0.07mg and Craving was
and (2) positive at baseline, four 0.03mg yield assessed via the
and negative withdrew of nicotine per Brief
subjective voluntarily prior cigarette. All Questionnaire on
evaluations of to the first doses of Smoking Urges
cigarettes in experimental research (QSU)
adolescent daily session, and one cigarettes were
cigarette smokers, participant was available in
using a within- withdrawn by the menthol and
subjects PI for excessive nonmenthol
experimental rescheduling; versions,
design, leaving 50 Positive and
participants who Negative Affect
completed all Scale (PANAS)
sessions.
18 Hom et al. West To explore the A randomized 233 Teens aged Brief Not telling Not telling the Teens who
(2013) Virginia, effects of a teen 14-19 years from Intervention how long name of increased the
USA. smoking controlled trial. West Virginia intervention instrument of number of days
(WV) public high (standard of was conducted. meassurement. on which they
cessation schools care), received at least
intervention They did a 20 minutes of
supplemented (N = 19) between Not-On- Physical Activity
Tobacco (N-O- 3 month exercise were
with a physical 2006 and 2009. Survey significantly
activity module T, teen follow-up of
cessation the outcome more likely to
on participants’ reduce their
physical program), or N-
O-T plus a daily cigarette
activity physical use, with those
outcomes. A in the N-
secondary aim activity module OT+FIT
examined the (N-O-T+FIT). condition having
relationship the highest
between likelihood of
participants’ reducing
 physical smoking. Teens
in the N-O-
activity outcomes T+FIT condition
and postprogram who increased
smoking the number of
intensity. days on which
they received at
least 30 minutes
of exercise were
significantly
more likely than
those in other
groups to quit
smoking.
19 Espada et al. Spanyol To test outcome A randomized Spanish cigarettes Project EX The clinic Questionnaire Project EX had a
(2015) of Project EX controlled trial smoker 13-19 Curriculum program was significant
with Spanish years of age. delivered in influence for
adolescent There were 211 classrooms future smoking
smokers at over five-week expectation.
baseline (112 period. The Project EX
program group, first three significantly
99 controlled weeks of the reduced future
group) clinic delivery, nicotine
two clinic dependence
session were
delivered each
week. One
clinic session
was held each
week over the
subsequent two
weeks. These
sessions held
after school.
The activities
include:
talkshow,
game and
meditation