💥 Cambridge O-Level Biology 5090: Coordination & Control + Plant Responses
🧠 14.1 Mammalian Nervous System
        Concept                                     Summary
                    Integration of body functions by nervous system (fast, electrical impulses)
Coordination
                    or endocrine system (slow, chemical hormones).
Nervous system =
                    CNS = brain + spinal cord; PNS = nerves connecting CNS to the body.
CNS + PNS
                    Sensory: sense organ → CNS; Relay: within CNS; Motor: CNS →
Types of neurones
                    effectors (muscles/glands). (Draw the 3 neurones!)
                    Along neurones as electrical signals. Direction: receptor → CNS →
Impulse travel
                    effector.
                    🧠 Involuntary, fast, protective. Pathway: Stimulus → Receptor → Sensory
Reflex arc          neurone → Relay neurone (spinal cord) → Motor neurone → Effector
                    (muscle/gland) → Response.
Reflex examples     Blink reflex, knee jerk, coughing, pupil reflex.
                    Gap between neurones. Impulse triggers neurotransmitter release →
Synapse             diffuses across synaptic gap → binds receptors → impulse in next
                    neurone.
                    Neurotransmitter only on one side; receptors only on next neurone → one-
One-way only
                    way transmission.
🧠 Memory Hack: RSRMER → Reflex Arc order = Receptor → Sensory → Relay → Motor →
Effector → Response
📌 Exam Tip: Always use "rapid and automatic" when defining reflex. Examiner expects
"without conscious control".
👁️ 14.2 Mammalian Sense Organs
    Structure                                        Function
Cornea              Refracts light onto lens.
                    Controls pupil size via circular (contract in light) and radial muscles
Iris
                    (contract in dark).
Pupil               Allows light into eye.
Lens                Focuses light onto retina.
     Structure                                        Function
Ciliary muscles       Contract/relax to change lens shape.
Suspensory
                      Pull lens flat/thick based on tension.
ligaments
Retina                Light receptors (rods for dim light, cones for color).
Fovea                 Sharp vision – high cone density.
Optic nerve           Carries impulses to brain.
Blind spot            No receptors – where optic nerve exits.
📌 Pupil Reflex:
      Bright light → circular muscles contract, radial relax → pupil constricts
      Dim light → radial contract, circular relax → pupil dilates
       🌀 Antagonistic muscle action
📌 Accommodation:
Object Ciliary muscles Ligaments Lens        Light
Near Contract          Loosen   Thicker More refraction
Distant Relax          Tighten  Thinner Less refraction
💡Tip: "Closer = Fatter lens" – Think zooming in!
🧠 14.3 Mammalian Hormones
  Hormone          Gland                              Function
                         Fight/flight: ↑HR, ↑BR, dilates pupils, converts glycogen to
Adrenaline Adrenal gland
                         glucose.
             Pancreas
Insulin                  Lowers blood glucose by converting glucose → glycogen (liver).
             (islets)
             Pancreas
Glucagon                 Raises glucose: glycogen → glucose.
             (islets)
FSH          Pituitary   Stimulates follicle to develop and release oestrogen.
LH           Pituitary   Triggers ovulation + corpus luteum.
Oestrogen Ovary          Builds uterus lining; female secondary traits.
Progesterone Ovary       Maintains uterine lining.
Testosterone Testes      Male secondary sexual traits.
🧠 Hormone = chemical messenger carried by blood, made by glands, affects target organs
only.
📌 Nervous vs Hormonal Control
  Feature          Nervous            Hormonal
Speed        Fast                  Slow
Duration     Short                 Long
Transmission Electrical (neurones) Chemical (blood)
Target       Specific              Widespread
Reversible Usually                 Sometimes not
🔁 14.4 Homeostasis
📘 Definition: Maintenance of constant internal environment (e.g., temp, water, glucose).
📌 Negative Feedback: Change detected → corrective action → returns to set point.
🧠 "Body reacts to oppose the change." Example: ↑ glucose → insulin → ↓ glucose.
🌡️ 14.5 Temperature Control
    Component                                  Role
Hypothalamus         Brain region detecting blood temperature.
Skin receptors       Detect external temp.
Hair erector muscles Contract = traps air (insulation). Relax = lose heat.
Sweat glands         Produce sweat → evaporates = cools body.
Blood vessels        Vasodilation (heat loss), vasoconstriction (retain heat).
Shivering            Muscle contractions generate heat.
📌 Mnemonic: SV SHV → Sweat, Vasodilation, Shiver, Hair, Vasoconstriction
🍭 14.6 Blood Glucose Control
Hormone                                   Action
Insulin ↓ Blood glucose – stimulates glucose uptake + conversion to glycogen (liver).
Hormone                                    Action
Glucagon ↑ Blood glucose – stimulates glycogen → glucose (liver).
📌 Type 1 Diabetes:
      Cause: Islet cells don’t produce insulin.
      Signs: High blood glucose, glucose in urine.
      Treatment: Insulin injections.
🧠 Hack: Glucagon = Go ↑, Insulin = Into cells ↓
🌱 15.1 Coordination in Plants
  Tropism                              Description
Phototropism Growth towards light (shoots = positive).
Gravitropism Growth in response to gravity (roots = positive, shoots = negative).
📌 Auxin (Plant Hormone):
      Made in shoot tip.
      Moves down stem.
      Uneven distribution in light/gravity.
      Stimulates elongation (in shoots only).
🧠 Hack: Light side = Less auxin → Slower growth
Shade side = More auxin → Elongates more → Bends towards light
🎯 Past Paper Gold (2020–2024)
       PP Question                          MS Tip / Examiner Report Insight
2023 ON 14.1 (Reflex       Must include correct sequence AND key terms “rapid, automatic” to
arc)                       score full.
2022 JN 14.2 (Pupil        Describe muscles by name: circular and radial. Just saying “muscle”
reflex)                    = 0.
2021 ON 14.3               Use phrases like “prepares body for action”, “fight/flight”, not just
(Adrenaline)               “increases heart rate”.
2020 JN 14.4 (Negative
                           Draw diagram + define “set point” to impress examiner.
feedback)
       PP Question                      MS Tip / Examiner Report Insight
                        Always state insulin lowers blood glucose by converting glucose
2021 ON 14.6 (Diabetes)
                        to glycogen—not just “stores glucose”.
🚀 Final Hacks for Distinction (6/5 Level)
🧠 Mnemonic Vault:
      RSRMER – Reflex arc
      CRaZY HORMONE PEST – Cortisol, Repro (testes, ovaries), Adrenaline, Zzz
       (melatonin), Yawn, Progesterone, Estrogen, Serotonin, Testosterone
      VVSHH – Vasodilation, Vasoconstriction, Shivering, Hairs, Hypothalamus
🧠 Experiment Triggers:
      Reflex test → knee-jerk + eye blink
      Pupil reflex → lamp + mirror
      Tropism → rotating clinostat or directional light
⚠️ Examiner Alerts:
      Don’t say “brain controls reflex” → spinal cord!
      Don’t confuse glucose/glycogen/glucagon!
      Always define stimulus, effector, receptor with examples.
Would you like diagrams and visual cheatsheets for each section next (reflex arc, synapse, eye,
tropisms)?