FNH Notes (Unit-4)
FNH Notes (Unit-4)
CALCULATION
Syllabus:
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1. TYPE I DISORDERS: LIFESTYLE & STRESS-RELATED DISEASES
      Type I disorders are non-communicable, chronic diseases that often result from
   long-term unhealthy lifestyle habits and persistent stress. They tend to emerge slowly,
   often without early symptoms, and are closely tied to behavioural choices, environmental
   factors, and psychological health.
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  6. Obesity: Excess weight strains the heart, increases blood pressure, and
     contributes to conditions like diabetes and high cholesterol, all of which raise
     the risk of CVD.
  7. Physical Inactivity: Lack of exercise weakens the heart and contributes to
     obesity and other risk factors for CVD.
Physiological Impact
   Stress causes vasoconstriction (narrowing of blood vessels), raising blood
      pressure.
   Repeated exposure leads to atherosclerosis (plaque buildup in arteries).
       Blood flow to heart and brain can be blocked, leading to heart attacks or
        strokes.
Risk:
   Age: The risk of CVD increases with age, particularly after 65.
   Gender: Men are generally at higher risk
   Family history: A family history of heart disease increases the risk
   Ethnicity: Certain ethnic groups, such as African Americans, have a higher risk
    of CVD
   Socioeconomic Factors: Low socioecomonic status is associated with higher
    rates of CVD due to limited access to healthcare, unhealthy lifestyle habits and
    other factors.
Symptoms:
       Chest Pain: Discomfort, pressure, squeezing or pain in the chest
       Shortness of breath: Difficulty breathing, especially during physical activity
       Fatigue: Feeling unusually tired or weak.
       Dizziness or Light-headedness: Feeling faint or woozy.
       Palpitations: Irregular or rapid heartbeats
       Swelling: Edema, often in the legs, ankles or abdomen.
       Nausea or Indigestion: Unexplained stomach discomfort.
Preventive Measures:
   Healthy Diet: Emphasize fruits, vegetables, whole grains, lean proteins, and
    healthy fats while limiting saturated and trans fats, salt, and added sugars.
   Regular Exercise: Aim for at least 150 minutes of moderate-intensity aerobic
    exercise or 75 minutes of vigorous-intensity exercise per week.
   Maintain a Healthy Weight: Achieve and maintain a healthy weight through
    diet and exercise. Quit Smoking: Seek assistance if needed to quit smoking and
    avoid exposure to secondhand smoke.
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      Manage Stress: Practice stress-reduction techniques such as meditation, yoga,
       or deep breathing exercises.
      Control Blood Pressure and Cholesterol: Monitor blood pressure and
       cholesterol levels regularly and follow medical advice to keep them within
       healthy ranges.
      Limit Alcohol: If you drink alcohol, do so in moderation.
      Regular Health Check-ups: Schedule regular check-ups with a healthcare
       provider to assess cardiovascular health and address any concerns.
  Types of Cardiovascular Disease:
  ● Coronary heart disease – a disease of the blood vessels supplying the heart
    muscle;
  ● Cerebrovascular disease – a disease of the blood vessels supplying the brain;
  ● Peripheral Arterial disease – a disease of blood vessels supplying the arms and
    legs;
  ● Rheumatic heart disease – damage to the heart muscle and heart valves from
    rheumatic fever, caused by streptococcal bacteria;
  ● Congenital heart disease – birth defects that affect the normal development and
    functioning of the heart caused by malformations of the heart structure from birth;
  ● Deep Vein Thrombosis and Pulmonary Embolism – blood clots in the leg veins,
    which can dislodge and move to the heart and lungs.
1.2 Hypertension (High Blood Pressure)
  Definition
     Hypertension is a condition where the force of blood against the artery walls is
  consistently too high (above 130/80 mmHg). Often called a “silent killer” because it
  has no obvious symptoms but causes serious damage over time.
  Lifestyle and Stress Factors (Causes)
     1. High Sodium Intake: Causes the body to retain water, increasing blood volume
        and pressure.
     2. Obesity: Extra fat, especially around the abdomen, demands more oxygen and
        blood, increasing pressure on arteries.
     3. Lack of Exercise: Contributes to higher resting heart rates and less flexible
        blood vessels.
     4. Stress and Anxiety: Activates the sympathetic nervous system, increasing
        blood pressure temporarily; chronic stress makes it persistent.
     5. Poor Time Management and Job Pressure: Mental strain without coping
        strategies leads to chronic hypertension.
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   6. Substance Use: Tobacco and alcohol increase vascular resistance and stress
      hormone levels.
Physiological Impact
    Constant high pressure thickens artery walls, reducing blood flow.
    Can damage kidneys, eyes, and brain, and cause heart enlargement.
    Increased risk of stroke, heart attack, and aneurysms.
Risk Factors:
    Obesity: Excess body weight increases the workload on the heart and raises
      blood pressure
    Physical Inactivity: Lack of regular exercise weakens the heart and
      cardiovascular system.
    Unhealthy Diet: High sodium intake, low potassium intake and consumption of
      processes foods contribute to hypertension.
    Tobacco Use: Smoking and chewing tobacco can raise blood pressure
      temporarily and damage blood vessels over time.
    Excessive Alcohol Consumption: Heavy drinking can raise blood pressure and
      damage the heart.
    Stress: Chronic stress can contribute to hypertension through hormonal changes
      and unhealthy coping mechanisms.
Symptoms:
   Headaches: Particularly in the back of the head and neck, especially in the
    morning.
   Shortness of breath: Difficulty breathing or felling breathless with exertion.
   Chest Pain: Often as a result of heart strain due to hypertension.
   Dizziness or Fainting: Due to inadequate blood flow to the brain.
   Blurred Vision: Resulting from damage to blood vessels in the eyes.
   Fatigue: Feeling tired or lethargic despite adequate rest.
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       Stress Management: Practice relaxation such as deep breathing, meditation or
        yoga to manage stress effectively.
       Quit Smoking:
1.3 Obesity
   Definition
      Obesity is the accumulation of excessive body fat, typically measured by a Body
   Mass Index (BMI) of 30 or higher. It increases the risk of diabetes, heart disease,
   certain cancers, and joint problems.
   Lifestyle and Stress Factors (Causes):
      1. High-Calorie Diets: Frequent consumption of processed, high-fat, and sugary
         foods leads to a calorie surplus.
      2. Sedentary Lifestyle: Prolonged sitting, lack of daily movement, and screen
         time lower calorie expenditure.
      3. Emotional Eating: Stress, anxiety, or depression may lead to binge eating or
         comfort eating.
      4. Lack of Sleep: Disrupts hormones (leptin and ghrelin) that regulate appetite.
      5. Endocrine Disruption: Chronic stress alters the HPA axis, leading to high
         cortisol which encourages fat storage (especially belly fat).
      6. Poor Meal Timing: Skipping meals or eating late at night disrupts metabolism.
      7. Genetics: Genetic factors can influence an individual's susceptibility to obesity
         by affecting metabolism, appetite regulation, and fat storage.
Physiological Impact
    Fat cells release inflammatory chemicals that impair insulin use, increasing
      diabetes risk.
    Excess weight strains joints, heart, and liver.
    Visceral fat (around organs) is especially dangerous and linked to metabolic
      syndrome.
Risk Factors:
    Poor diet: High consumption of processed food, sugary beverages, fast food and
      snacks contributes to obesity.
    Physical Inactivity: Lack of regular exercise or physical activity reduces energy
      expenditure and promotes weight gain.
Prevention and Management:
    Healthy Diet: Emphasize whole, nutrient-dense foods such as fruits, vegetables,
      lean proteins, and whole grains while minimizing processed foods, sugars, and
      saturated fats.
    Regular Exercise: Engage in regular physical activity, aiming for at least 150
      minutes of moderate-intensity aerobic exercise per week.
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      Behavioral Changes: Practice portion control, mindful eating, and healthy cooking
       techniques to maintain a balanced diet and control calorie intake.
      Medical Intervention: In some cases, medication or surgical interventions such as
       bariatric surgery may be recommended for severe obesity or when lifestyle
       interventions alone are insufficient.
      Lifestyle Modification Programs: Participate in structured lifestyle intervention
       programs that combine dietary changes, physical activity, and behavioral therapy
       for sustainable weight loss and management.
  INTERCONNECTION BETWEEN DISORDERS
    These conditions are closely linked:
       Obesity increases the risk of hypertension and cardiovascular disease.
       Hypertension and obesity both strain the heart, leading to CVDs.
       Stress is a common thread, triggering poor behaviors and direct biological
          changes.
  Summary Table
                   Key Lifestyle                                 Health
  Disorder                                Key Stress Impacts
                   Factors                                       Consequences
                                          Inflammation, high
                   Diet, inactivity,                             Heart attack, stroke,
Cardiovascular                            heart rate, artery
                   smoking, alcohol                              heart failure
                                          damage
                                          Sympathetic            Kidney failure,
                   Salt, inactivity,
Hypertension                              activation, cortisol   stroke, heart
                   obesity, alcohol
                                          increase               damage
                   Overeating,
                                          Hormonal imbalance,    Diabetes, CVDs,
Obesity            sedentary habits,
                                          emotional eating       arthritis, fatty liver
                   poor sleep
  Preventive Measures
      Regular physical activity (at least 30 min/day)
      Balanced diet (low in salt, sugar, and saturated fats)
      Stress management (meditation, therapy, hobbies)
      Adequate sleep (7–8 hours)
      Avoiding tobacco and limiting alcohol
      Regular health screenings
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2. TYPE II DISORDERS:
     a. CANCER:
               Cancer is an abnormal growth of cells which has the ability to involve
        adjacent tissues and even distant organs and eventful death of the affected patient if
        the tumour has progressed to the stage where it cannot be treated.
        Categories of Cancer:
           There are numerous types of cancer, which can be categorized based on various
           criteria such as the affected organ or tissue, the type of cell from which the
           cancer originates, and its behaviour. Here are some common categories of
           cancer based on these criteria.
                Organ or Tissue Specific
                   o Breast cancer: Cancer that forms in the cells of the breasts, most
                      commonly affecting women but can also occur in men.
                   o Lung cancer: Cancer that begins in the lungs, often associated with
                      smoking but can also occur in non-smokers.
                   o Prostate cancer: Cancer that develops in the prostate gland, a part of
                      the male reproductive system.
                   o Colorectal cancer: Cancer that starts in the colon or rectum, usually
                      developing from polyps in the lining of the intestine.
                   o Skin cancer (such as melanoma): Cancer that forms in the skin cells,
                      including melanoma which is the most serious type of skin cancer.
                   o Brain cancer (such as glioblastoma): Cancer that originates in the
                      brain or spinal cord, often aggressive and difficult to treat.
                   o Liver cancer: Cancer that begins in the liver cells, commonly
                      associated with underlying liver disease such as cirrhosis.
                   o Ovarian cancer: Cancer that forms in the ovaries, often diagnosed at
                      an advanced stage due to vague symptoms.
                   o Pancreatic cancer: Cancer that starts in the pancreas, usually
                      diagnosed at an advanced stage with a poor prognosis.
                   o Bladder cancer: Cancer that develops in the bladder, often
                      characterized by blood in the urine and frequent urination.
                   o Thyroid cancer: Cancer that begins in the thyroid gland, usually
                      highly treatable with a high survival rate.
                Cell Type
                   o Carcinoma: Cancer that starts in epithelial cells (tissues that cover the
                      body's surfaces and line the internal organs). Examples include breast,
                      lung, prostate, and colorectal cancer.
                   o Sarcoma: Cancer that arises from connective tissues such as bones,
                      muscles, cartilage, or blood vessels.
                   o Leukemia: Cancer of the blood or bone marrow, characterized by the
                      overproduction of abnormal white blood cells.
                   o Lymphoma: Cancer that begins in the lymphatic system, which is part
                      of the body's immune system.
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          o Myeloma: Cancer of plasma cells, a type of white blood cell,
             primarily affecting bone marrow.
          o Germ Cell Tumors: Cancer that starts in germ cells, the cells that
             develop into sperm and eggs. Examples include testicular and ovarian
             cancer.
         Behaviour and Growth
          ● Benign tumors: Non-cancerous growths that do not spread to other
            parts of the body. eg:Fibroadenoma, adenoma, Meningioma.
          ● Malignant tumors: Cancerous growths that can invade nearby tissues
            and spread to other parts of the body (metastasis). Eg: Breast
            carcinoma, Lung adenocarcinoma, Melanoma.
          ● In situ tumors: Cancer that is confined to the tissue where it originated
            and has not invaded surrounding tissues. Eg: Ductal carcinoma in situ
            (DCIS), Carcinoma in situ of the cervix, Colon adenoma
         Hereditary vs. Sporadic
          o Hereditary cancers: Caused by inherited genetic mutations that
             increases the risk of developing cancer. Examples include hereditary
             breast and ovarian cancer syndrome (BRCA mutations) and Lynch
             syndrome (hereditary non-polyposis colorectal cancer).
          o Sporadic cancers: Develop due to a combination of genetic,
             environmental, and lifestyle factors, without a clear hereditary
             predisposition.
b. DIABETICS
     A disorder of metabolism where the pancreas produces little or no insulin or the
     cells do not respond to the insulin produced. Glucose, or sugar, builds up in the
     blood, overflows and is lost into urine. Meanwhile the cells are denied of their
     source of energy.
Types of Diabetes:
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Type 1 Diabetes:
  ● Autoimmune destruction of insulin-producing beta cells in the pancreas.
  ● Genetic predisposition or family history.
  ● Environmental triggers like viral infections may play a role.
Type 2 Diabetes:
  ● Insulin resistance, where the body's cells do not respond effectively to insulin.
  ● Genetic factors and family history.
  ● Obesity and sedentary lifestyle.
  ● Poor diet high in refined sugars and carbohydrates.
  ● Aging, as the risk increases with age
Causes:
    Tobacco use
    Environmental Carcinogens
    Dietary Factors
    Alcohol Consumption
    Obesity and Overweight
    Ultraviolet(UV) Radiation
    Hormonal Factors
    Chronic Infections
    Genetic Predisposition
    Ageing
Risk Factors:
    Obesity and Overweight
    Family history
    Physical Inactivity
    Unhealthy diet
    Age
    Ethnicity
    Gestational Diabetes
    Poly Cystic Ovary Syndrome (PCOS)
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    Hypertension (High Blood Pressure)
    Impaired Glucose Tolerance (Pre-diabetes)
    History of Cardiovascular Disease
    Sleep Disorders
Preventive Measures:
     ❏     Healthy Eating
     ❏     Regular Physical Activity
     ❏     Weight Management
     ❏     Avoid Tobacco Use
     ❏     Limit Alcohol Consumption
     ❏     Regular Health Check-ups
     ❏     Manage Stress
     ❏     Sleep Hygiene
     ❏     Screenings and Early Detection
     ❏     Genetic Counseling (for individuals with family history)
     ❏     Medication Adherence (for individuals at high risk or with pre-diabetes)
     ❏     Education and Awareness
c. ULCERS
      An ulcer is a localized area of tissue erosion or damage within the body,
   commonly occurring in the digestive tract, skin or mucous membranes.
   Types of Ulcers:
       Pep c Ulcers:
            o Gastric Ulcer: Develops in the lining of the stomach.
            o Duodenal Ulcer: Occurs in the first part of the small intestine
               (duodenum).
       Pressure Ulcers (Bedsores): Develop due to prolonged pressure on the skin,
         typically over bony prominences, leading to tissue damage. Common in
         individuals who are bedridden or wheelchair-bound.
       Venous Ulcers (leg sores): Result from venous insufficiency, leading to
         poor circulation and tissue damage, often occurring on the lower legs or
         ankles.
       Arterial Ulcers: Caused by arterial insufficiency, usually associated with
         conditions like peripheral artery disease (PAD), resulting in inadequate
         blood supply to tissues and subsequent ulceration, often seen on the lower
         extremities.
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      Neurotrophic Ulcers: Occur due to nerve damage, commonly seen in
        individuals with diabetes or other neuropathic conditions, leading to
        decreased sensation and impaired wound healing.
      Corneal Ulcers: Ulcers affecting the cornea of the eye, often caused by
        infections, trauma, or underlying ocular conditions, which can lead to severe
        eye pain and vision loss if left untreated.
      Mouth Ulcers (Canker Sores): Small, painful ulcers that develop inside the
        mouth, commonly on the inner cheeks, lips, gums, or tongue, with various
        causes including injury, stress, hormonal changes, or immune system
        disorders.
      Ischemic Ulcers: Develop due to inadequate blood supply to tissues, often
        seen in conditions like atherosclerosis or vasculitis, leading to tissue necrosis
        and ulcer formation.
      Chemical Ulcers: Result from exposure to corrosive substances such as
        acids or alkalis, leading to tissue damage and ulceration, often seen in cases
        of ingestion or contact with these substances.
      Stress Ulcers: Develop in response to severe physiological stress, such as
        trauma, surgery, or critical illness, often occurring in the stomach or upper
        gastrointestinal tract.
Causes:
   Helicobacter pylori Infection
   Regular Use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
   Advanced Age
   Smoking
   Excessive Alcohol Consumption
   History of Ulcers
   Chronic Diseases (e.g., Diabetes, Cardiovascular Disease)
   Poor Dietary Habits
   High Stress Levels
   Genetic Predisposition
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Preventive Measures:
    Healthy lifestyle Practices
    Medication management
    Pressure ulcer prevention
    Venous ulcer prevention
    Arterial ulcer prevention
    Diabetes management
    Eye care
    Oral hygiene
    Cardiovascular health
    Stress management
d. ELECTROLYTE
      An electrolyte imbalance can occur if the body has too much or too little water.
   Electrolytes are minerals in the blood, tissues and elsewhere throughout the body.
      Types:
          Dehydration: Fluid Loss
          Hyponatremia: Low Sodium
          Hypernatremia: High Sodium
          Hypokalemia: Low Potassium
          Hyperkalemia: High Potassium
          Hypocalcemia: Low Calcium
          Hypercalcemia: High Calcium
          Hypomagnesemia: Low Magnesium
          Hypermagnesemia: High Magnesium
          Hypochloremia: Low Chloride
          Hyperchloremia: High Chloride
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Symptoms:
   Thirst
   Fatigue
   Muscle cramps
   Nausea and vomiting
   Irregular heartbeat
   Weakness
   Confusion
   Headache
   Seizures
   Swelling (edema)
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3. HEALTH INCIDES
       Health indices are measurements or indicators used to assess various aspects of health
   within population or individuals. These indices help in understanding the overall health
   status, identifying health disparities, monitoring trends over time and evaluating the
   effectiveness of health interventions. Some common health indices include:
    Life Expectancy: This index measures the average number of years a person is
       expected to live from birth. It provides a snapshot of overall health and healthcare
       effectiveness within a population.
    Infant Mortality Rate: This index measures the number of deaths of infants under
       one year of age per 1,000 live births in a given year. It reflects the health of newborns
       and the effectiveness of maternal and child healthcare services.
    Maternal Mortality Ratio: This index measures the number of maternal deaths per
       100,000 live births during pregnancy or within 42 days of termination of pregnancy. It
       reflects the quality of maternal healthcare services and access to prenatal care.
    Child Mortality Rate: This index measures the number of deaths of children under
       five years of age per 1,000 live births. It indicates the overall health and well-being of
       children and the effectiveness of healthcare services targeting this age group.
    Disease-specific Mortality Rates: These indices measure the number of deaths
       attributed to specific diseases or conditions, such as cardiovascular diseases, cancer,
       HIV/AIDS, tuberculosis, etc. They help in understanding the burden of specific health
       conditions and targeting interventions accordingly.
    Prevalence and Incidence Rates: These indices measure the proportion of
       individuals within a population who have a particular disease (prevalence) or the rate
       at which new cases of a disease occur (incidence). They provide insights into disease
       burden and transmission dynamics.
    Healthy Life Expectancy: This index measures the number of years an individual is
       expected to live in good health, free from disability or disease. It provides a more
       nuanced perspective on overall health by considering both longevity and quality of
       life.
    Healthcare Access and Utilization Indicators: These indices measure factors such
       as healthcare coverage, access to essential healthcare services, utilization rates of
       preventive and curative services, and healthcare expenditure per capita. They reflect
       the accessibility and affordability of healthcare services within a population.
    Health Behavior Indicators: These indices measure lifestyle factors and behaviors
       that influence health outcomes, such as tobacco use, alcohol consumption, physical
       activity levels, dietary habits, and adherence to preventive health practices.
    Environmental Health Indicators: These indices measure environmental factors that
       impact health, such as air and water quality, sanitation, access to clean drinking water,
       exposure to pollutants, and prevalence of vector-borne diseases.
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Preventive and Remedial Measures:
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         and other relevant conditions to detect them early when treatment is most
         effective.
       ● Stress Management: Support stress reduction techniques to mitigate the
         impact of stress on overall health.
       ● Education and Awareness: Raise awareness about the risk factors associated
         with these conditions and encourage proactive health behaviors.
       ● Infection Control: Address factors contributing to ulcers such as Helicobacter
         pylori infection through appropriate treatment and hygiene practices.
       ● Hydration: Encourage adequate fluid intake and electrolyte balance through a
         balanced diet and regular hydration.
     Remedial Measures:
       ● Medical Treatment: Provide medical treatment tailored to the specific
         condition, which may include chemotherapy, radiation therapy, surgery, insulin
         therapy, or medications for ulcer management and electrolyte imbalance.
       ● Nutritional Support: Offer nutritional counseling and support to manage
         dietary requirements and side effects of treatment.
       ● Psychosocial Support: Provide emotional and psychological support to
         individuals and families coping with the diagnosis and treatment of these
         conditions.
       ● Rehabilitation: Offer rehabilitation services as needed to support recovery and
         improve quality of life post-treatment.
       ● Palliative Care: Provide palliative care for individuals with advanced or
         terminal illness to manage symptoms and improve comfort and quality of life.
  Obesity stems from imbalance between energy intake and energy expenditure.
  Reducing obesity requires addressing both, not just one.
  Humans are physiologically biased to achieve energy balance at high energy flux
   (high intake + high expenditure), not through low intake alone.
  Prevention of weight gain is more feasible than treatment, as the body defends
   against weight loss more than weight gain.
  Small behavior changes may suffice for prevention, while larger changes are needed
   for treatment.
 Framing the Issue
  Obesity results from positive energy balance, not just overconsumption or inactivity.
  Both energy intake and expenditure must be modified to address obesity.
  Energy balance theory can guide more effective interventions.
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Energy Balance: Definitions
     Components:
          o Energy intake (EIN): from food (protein, fat, carbs, alcohol).
          o Energy expenditure (EOUT): includes Resting Metabolic Rate (RMR),
             Thermic Effect of Food (TEF), and Energy Expended in Physical Activity
             (EEPA).
     Body weight changes only when EIN ≠ EOUT.
     Energy balance control timeframe varies by individual and impacts response to
      interventions.
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Debate: Is Physical Activity Still Relevant?
      Some claim food environment is more to blame than declining activity.
      Authors argue that early 20th-century declines in activity created conditions that
       allowed food environment to trigger obesity.
      Obesity raises RMR and EEPA, keeping total expenditure stable despite inactivity.
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Children and Obesity
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5. PLANNING A HEALTHY DIET
    Planning a healthy diet is essential for promoting overall well-being, maintaining a healthy weight, and
reducing the risk of chronic diseases such as diabetes, heart disease, and obesity. A healthy diet provides the
body with essential nutrients, maintains energy balance, and supports optimal physiological function. This
section outlines the core components, principles, tools, and international recommendations for effectively
planning a healthy diet.
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✔ Grains
At least half should be whole grains like brown rice, oats, and whole wheat bread.
✔ Dairy
Include low-fat or fat-free dairy products, such as milk, yogurt, and cheese, or fortified soy alternatives.
✔ Protein
Consume a variety including seafood, lean meats, poultry, eggs, legumes, nuts, seeds, and soy products.
✔ Oils
Choose unsaturated fats (e.g., olive, canola, avocado oil) over saturated or trans fats.
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8. Hydration and Physical Activity
      Drink 6–8 cups of water daily (more with physical activity or in hot climates)
      Limit sugar-sweetened beverages
      Combine healthy eating with regular physical activity (150 minutes per week minimum for adults)
       Planning a healthy diet involves more than just choosing the right foods—it’s about ensuring
adequacy, balance, moderation, variety, and nutrient density. By following evidence-based guidelines like
those from the Dietary Guidelines for Americans, USDA MyPlate, and the World Health Organization,
individuals can develop sustainable, culturally appropriate eating habits that support lifelong health.
Combining this with physical activity and nutrition education ensures a holistic approach to wellness.
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