Seat No.: _____                                                Enrolment No.
_____________
               GUJARAT TECHNOLOGICAL UNIVERSITY
                  PHARM. D. YEAR-1 EXAMINATION -SUMMER - 2024
Subject Code: 818805                                                        Date: 30/05/2024
Subject Name: Pharmaceutical Inorganic Chemistry
Time: 10:30AM TO 01:30PM                                                    Total Marks: 70
Instructions:
    1. Attempt any five questions.
    2. Make suitable assumptions wherever necessary.
    3. Figures to the right indicate full marks.
Q.1    (a)   Explain Geiger Muller counter. Write a note on clinical applications of                06
             radiopharmaceuticals.
       (b)   Enlist various types of redox titrations. Explain diazotization titration in detail.   04
       (c)   Classify the errors in pharmaceutical analysis with suitable examples.                 04
Q.2    (a)   Enumerate sources of impurities in pharmaceuticals. Explain the principle              06
             involved in the limit test of arsenic with a diagram.
       (b)   Define the following terms giving suitable examples.                                   04
             Sclerosing agents, Expectorants, Emetics, Antimicrobials
       (c)   Briefly explain solvents, titrants, and indicators used in non-aqueous titrations.     04
Q.3    (a)   Define and classify gastrointestinal agents with suitable examples. Give               06
             preparation, assay principle and uses of aluminium hydroxide gel.
       (b)   Define the following terms.                                                            04
             Accuracy, Precision, Limit test, Confidence limit
       (c)   1. Differentiate between iodometric and iodimetric titrations.                         04
             2. Comment: Equivalent weight of KMnO4 changes in acidic and alkaline
                media.
Q.4    (a)   Define and explain theory and different types of complexometric titration.             06
       (b)   Explain the pharmaceutical importance of transition elements and their                 04
             compounds.
       (c)   Write a note on end point detection for redox titration.                               04
Q.5    (a)   Explain the steps involved in the gravimetric analysis. Differentiate between          06
             volumetric and gravimetric analysis.
       (b)   Define buffer and buffer capacity. Explain the mechanism of buffer action              04
             along with a suitable example.
       (c)   Classify dental products with suitable examples. Write a brief note on anti-           04
             caries agents.
Q. 6   (a)   Differentiate between Mohr’s, and Volhard’s methods of argentometric                   06
             titrations.
       (b)   Define the following terms:                                                            04
             Normality, Common ion effect, Equivalence Point, pH
       (c)   Classify cathartics and explain any one cathartic agent in detail.                     04
Q.7    (a)   What is hydrolysis? Derive an equation for finding pH of the aqueous solution          06
             of salt of a weak acid and a strong base.
       (b)   Write an informative note on electrolytes used for the replacement therapy.            04
       (c)   Define the following terms giving suitable examples.                                   04
             Anti-oxidants, Preservatives, Filter aids, Adsorbents
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