STD MCQs
1. Which organism causes syphilis?
A. Neisseria gonorrhoeae
B. Treponema pallidum
C. Chlamydia trachomatis
D. Haemophilus ducreyi
Answer: B
2. A painless genital ulcer is typical of:
A. Chancroid
B. Genital herpes
C. Syphilis
D. Lymphogranuloma venereum
Answer: C
3. Which STD is characterized by a "strawberry cervix"?
A. Gonorrhea
B. Trichomoniasis
C. Syphilis
D. Candidiasis
Answer: B
4. The most common bacterial STD worldwide is:
A. Gonorrhea
B. Chlamydia
C. Syphilis
D. Mycoplasma genitalium
Answer: B
5. Which STD presents with a painful genital ulcer and tender lymphadenopathy?
A. Chancroid
B. Syphilis
C. Genital warts
D. HPV
Answer: A
6. Which test is used to confirm syphilis after a positive screening test?
A. VDRL
B. RPR
C. FTA-ABS
D. Gram stain
Answer: C
7. Which of the following is a complication of untreated gonorrhea in females?
A. Vaginal candidiasis
B. Endometriosis
C. Pelvic inflammatory disease
D. Ovarian torsion
Answer: C
8. Which STD is caused by a protozoan?
A. Syphilis
B. Gonorrhea
C. Trichomoniasis
D. Chlamydia
Answer: C
9. A patient presents with vesicles on the genitalia and painful urination. The likely cause is:
A. Syphilis
B. Herpes simplex virus
C. HPV
D. Molluscum contagiosum
Answer: B
10. Which STD can lead to cervical cancer?
A. HSV
B. HPV
C. Syphilis
D. Gonorrhea
Answer: B
11. What is the recommended treatment for primary syphilis?
A. Azithromycin
B. Ceftriaxone
C. Benzathine penicillin G
D. Metronidazole
Answer: C
12. Condyloma lata is seen in which stage of syphilis?
A. Primary
B. Secondary
C. Latent
D. Tertiary
Answer: B
13. Which STD is NOT typically screened for during routine pregnancy visits?
A. HIV
B. Syphilis
C. Gonorrhea
D. HPV
Answer: D
14. Neonatal conjunctivitis after vaginal delivery is most commonly caused by:
A. Gonorrhea
B. Chlamydia
C. HSV
D. CMV
Answer: B
15. Which is a gram-negative diplococcus?
A. Treponema pallidum
B. Neisseria gonorrhoeae
C. Chlamydia trachomatis
D. Gardnerella vaginalis
Answer: B
16. Jarisch-Herxheimer reaction is associated with treatment of:
A. Gonorrhea
B. Herpes
C. Syphilis
D. Chlamydia
Answer: C
17. Which organism causes lymphogranuloma venereum?
A. Treponema pallidum
B. Chlamydia trachomatis (L1-L3)
C. Neisseria gonorrhoeae
D. Haemophilus ducreyi
Answer: B
18. Which STD causes a "school of fish" pattern on Gram stain?
A. Gonorrhea
B. Chancroid
C. Trichomoniasis
D. Mycoplasma
Answer: B
19. Which is a common complication of neonatal herpes?
A. Blindness
B. Pneumonia
C. Encephalitis
D. Deafness
Answer: C
20. Reiter syndrome (reactive arthritis) is associated with which STD?
A. Gonorrhea
B. Syphilis
C. Chlamydia
D. Trichomoniasis
Answer: C
21. What is the treatment of choice for gonorrhea?
A. Metronidazole
B. Azithromycin
C. Doxycycline
D. Ceftriaxone
Answer: D
22. Which of the following presents with painless ulcers and painful inguinal lymphadenopathy?
A. HSV
B. LGV
C. Chancroid
D. HPV
Answer: B
23. Which virus is the most common cause of genital warts?
A. HPV 16
B. HPV 18
C. HPV 6 and 11
D. HSV-2
Answer: C
24. Which STD increases the risk of acquiring HIV?
A. HPV
B. Chlamydia
C. Syphilis
D. All of the above
Answer: D
25. The "clue cells" on wet mount are seen in:
A. Gonorrhea
B. Bacterial vaginosis
C. Candidiasis
D. Trichomoniasis
Answer: B
26. A newborn with snuffles, rash on palms and soles may have:
A. Neonatal HSV
B. Congenital syphilis
C. Congenital toxoplasmosis
D. Neonatal chlamydia
Answer: B
27. Which STD has an incubation period of around 3 weeks?
A. HSV
B. Syphilis
C. Chlamydia
D. Gonorrhea
Answer: B
28. Which STD is most commonly asymptomatic in women?
A. Chlamydia
B. Gonorrhea
C. Syphilis
D. HPV
Answer: A
29. Fitz-Hugh-Curtis syndrome is associated with:
A. Gonorrhea
B. Chlamydia
C. Syphilis
D. HSV
Answer: B
30. The "donovan bodies" are seen in:
A. Granuloma inguinale
B. Chancroid
C. Syphilis
D. Gonorrhea
Answer: A
31. Most common cause of genital ulcer in the USA:
A. HSV
B. HPV
C. Syphilis
D. Chancroid
Answer: A
32. Which virus causes recurrent painful genital ulcers?
A. HSV-1
B. HSV-2
C. HPV
D. CMV
Answer: B
33. Painless verrucous genital lesions suggest:
A. HSV
B. HPV
C. Syphilis
D. LGV
Answer: B
34. A "moth-eaten" appearance of the skull on X-ray is seen in:
A. Congenital syphilis
B. Chlamydia
C. HSV
D. Gonorrhea
Answer: A
35. Which STD causes urethritis but cannot be seen on Gram stain?
A. Gonorrhea
B. Trichomonas
C. Chlamydia
D. Syphilis
Answer: C
36. Which STDs are treated together due to frequent co-infection?
A. Syphilis and Chlamydia
B. Gonorrhea and Chlamydia
C. HSV and HPV
D. Trichomonas and Syphilis
Answer: B
37. A painless ulcer with dark-field positive spirochetes suggests:
A. HSV
B. Syphilis
C. Chancroid
D. LGV
Answer: B
38. Which test is used for early detection of HIV?
A. ELISA
B. Western blot
C. HIV PCR
D. Rapid antigen test
Answer: C
39. Partner notification and treatment is important in all except:
A. Chlamydia
B. Gonorrhea
C. HSV
D. Syphilis
Answer: C
40. Which of the following is not a reportable STD in many countries?
A. Syphilis
B. Gonorrhea
C. Chlamydia
D. HPV
Answer: D
