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Biopharmaceutics 2024

The document outlines the Even Semester Exam for the Pharmacy course, specifically for the B. Pharma VI Semester, focusing on Biopharmaceutics and Pharmacokinetics. It includes three parts: Part A consists of 20 short answer questions, Part B has 3 detailed questions with 2 to be attempted, and Part C includes 8 questions where 7 need to be answered. The exam covers various topics such as drug absorption, pharmacokinetic models, and bioequivalence.

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mdrashidanwar332
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38 views1 page

Biopharmaceutics 2024

The document outlines the Even Semester Exam for the Pharmacy course, specifically for the B. Pharma VI Semester, focusing on Biopharmaceutics and Pharmacokinetics. It includes three parts: Part A consists of 20 short answer questions, Part B has 3 detailed questions with 2 to be attempted, and Part C includes 8 questions where 7 need to be answered. The exam covers various topics such as drug absorption, pharmacokinetic models, and bioequivalence.

Uploaded by

mdrashidanwar332
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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EVEN SEMESTER EXAM-2024

Course: Pharmacy
Branch: B. Pharma Semester: VI
Subject Code: BP604T Subject Name: Biopharmaceutics and Pharmacokinetics
Time: 03 Hrs Marks:75
…………………………………………………………………………………………………………………………………………………
PART A
(QUESTION NO. 1 TO 20, ATTEMPT ALL QUESTIONS) (20 x 1 = 20)
1. Define prodrug with one example.
2. What is relative and absolute bioavailability?
3. Enlist methods used to maintain sink condition.
4. Define clearance. What are its units?
5. What do you mean by loading dose & maintenance dose?
6. Define volume of distribution?
7. What is Biopharmaceutics classification system (BCS) of drugs?
8. How will you define steady state drug levels?
9. Define nonlinear pharmacokinetics.
10. What is the clinical significance of protein binding?
11. What is perfusion rate?
12. Categorize different types of pharmacokinetic models.
13. Identify the various barriers for drug distribution.
14. Outline the term bioequivalence.
15. Write Michaelis-Menten equation.
16. Give the advantages of physiological models.
17. What is half-life of drug?
18. Define the term dissolution.
19. Enlist methods to enhance solubility of poorly water soluble drug.
20. Define enantiotropy and monotroph with example.
PART B
(QUESTION NO. 21 TO 23 ATTEMPT ANY 2 QUESTIONS) (2 x 10 = 20)
21. Discuss in detail two-compartment open model for a drug administered as IV Bolus. Give the
schematic representation, graphs and equations for the same.
22. Explain the various factors influencing drug absorption through GIT. Enumerate factors responsible
for protein-drug binding.
23. Differentiate between the bioavailability and bioequivalence. Describe in brief about various
methods for measurement of bioavailability.
PART C
(QUESTION NO. 24 TO 32 ATTEMPT ANY 7 QUESTIONS) (7 x 5 = 35)
24. Write a note on First-Pass metabolism.
25. Enlist in-vitro dissolution models. Explain any one in -vitro drug dissolution model.
26. Discuss in brief about Non compartmental analysis.
27. Describe the various factors effecting renal excretion of drugs.
28. Compare the dissimilarities between active and passive transport of drugs?
29. Elaborate in brief about the theories of drug dissolution.
30. What is elimination? Discuss in brief about the pathways of drug metabolism.
31. Enlist various study designs used in bioequivalence studies. Discuss about Latin square design.
32. Describe the kinetics of capacity-limited or saturable processes of non-linearity.

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