Enfermedades Cardiovasculares
Enfermedades Cardiovasculares
THEMATIC ARTICLE
Maria Luiza Sady Prates Pinheiro (https://orcid.org/0000-0001-6199-7092) 1
Luís Antônio Batista Tonaco (https://orcid.org/0000-0001-9660-2900) 2
Mariana Santos Felisbino-Mendes (https://orcid.org/0000-0001-5321-5708) 2
Jorge Gustavo Velásquez-Meléndez (https://orcid.org/0000-0001-8349-5042) 2
Deborah Carvalho Malta (https://orcid.org/0000-0002-8214-5734) 2
Alexandra Dias Moreira (https://orcid.org/0000-0002-4477-5241) 2
Abstract The aim is to analyze the association between the ideal cardiovascular health score and the self-reported
diagnosis of depression in Brazilian adults. Cross-sectional study, with 57,898 Brazilian adults from the 2019 National
Health Survey. Presence of self-reported depression. Exposures: behavioral scores (BMI, smoking, diet, physical activity,
ideal if ≥3 ideal factors), biological (smoking, dyslipidemia, hypertension and diabetes, ideal if ≥3 ideal factors) and
cardiovascular health (all factors, ideal if ≥4 ideal factors), based on the score proposed by the American Heart Asso-
ciation. They were categorized as poor/intermediate or ideal. Associations were tested using logistic regression models
adjusted for sociodemographic characteristics. The prevalence of depression was 11.1%. All scores classified as ideal
were inversely associated with depression after adjustments for sociodemographic variables (Ideal behavioral score: OR:
0.58 [95%CI: 0.48-0.70], ideal biological score: OR: 0.48 [95%CI: 0.43-0.53] and ideal cardiovascular health: OR: 0.53
[95%CI: 0.48-0.59]). The ideal cardiovascular health score was inversely associated with the self-reported diagnosis of
depression among Brazilian adults.
Key words Depression, Cardiovascular diseases, Risk Factors for Heart Disease, Epidemiological Surveys
1
Programa de Pós-
Graduação em Enfermagem,
Escola de Enfermagem,
Universidade Federal de
Minas Gerais (UFMG). Av.
Prof. Alfredo Balena 190,
Santa Efigênia. 30130-100
Belo Horizonte MG Brasil.
malusady@gmail.com
2
Departamento de
Enfermagem Materno
Infantil e Saúde Pública,
Escola de Enfermagem,
UFMG. Belo Horizonte MG
Brasil.
Cien Saude Colet 2025; 30:e08822023
2
Pinheiro MLSP et al
the components of the scores by gender, are de- al category. In the behavioral score, 11.51%
scribed in Table 1, also considering stratification (95%CI: 11.01-12.02) prevalence of depression
by age group. was observed in the poor/intermediate category
The prevalence of depression was 16.18% and 7.2% (95%CI: 6.12-8.46) in the ideal cate-
(95%CI: 15.42-16.98) in women and 5.49% gory. In the biological score, 17.51% (95%CI:
(95%CI: 5.03-5.99) in men, 9.80% (95%CI: 16.36-18.72) had depression in the poor/inter-
9.15-10.41) in individuals aged 18-49, 13.20% mediate category and 9.27% (95%CI: 8.8-9.76)
(95%CI: 12.09-14.37) aged 50-59 and 12.90% in the ideal category (Table 2).
(95%CI: 11.98-13.90) aged 60 or over. These and Having ideal cardiovascular health scores
other prevalences of depression by sociodemo- was found to be inversely associated with self-re-
graphic characteristics are described in Table 2. ported diagnosis of depression among Brazil-
The prevalence of depression was higher in ian adults in the unadjusted logistic regression
the poor/intermediate categories for all scores. models. Furthermore, statistical significance
The prevalence of depression was higher in in- was maintained after adjusting for sociodemo-
dividuals with a score in the poor/intermediate graphic variables (Model 1), with the following
category, with 15.27% (95%CI: 14.43-16.14) in OR values for self-reported depression: 0.53
the cardiovascular health score, while 8.77% (95%CI: 0.48-0.59) for ideal vs. intermediate/
(95%CI: 8.26-9.31) were classified in the ide-
Table 1. Prevalence of the variables that make up the cardiovascular health score and self-reported depression
among Brazilian adults according to sex and age group. National Health Survey, 2019.
Sex Age group
Variables Male Female 18 to 49 50 to 59 years 60 and
(%) (%) years old (%) old (%) over (%)
Smokinga,b
Ideal 58.15 64.85 69.80 53.30 47.00
Dieta,b
Ideal 1.20 2.35 1.20 2.20 1.80
Physical Activitya,b
Ideal 35.20 29.30 36.15 28.80 24.00
BMIa,b
Ideal 36.40 40.85 40.35 34.30 38.20
Behavioral Score*a,b
Ideal 8.70 10.00 11.60 7.00 5.30
Blood Pressurea,b
Ideal 76.00 72.85 8.80 6.45 45.00
Diabetesb
Ideal 92.00 91.55 9.70 88.40 79.40
Cholesterola,b
Ideal 86.50 81.00 90.50 77.00 83.60
Biological Score**a,b
Ideal 78.80 76.70 91.00 68.10 5.00
Cardiovascular score***b
Ideal 64.60 63.70 77.40 52.35 38.30
Depressiona,b
Yes 5.50 16.20 9.80 13.20 12.90
Notes: 95%CI: 95% Confidence Interval; BMI: Body Mass Index. *3 or more ideal factors (BMI, diet, smoking, physical activity);
**3 or more ideal factors (smoking, dyslipidemia, hypertension and diabetes); ***4 or more ideal factors (BMI, diet, smoking,
physical activity, dyslipidemia, hypertension and diabetes). a P-value of the chi-square test between sex and components of the
cardiovascular health score <0.05; b P-value of the chi-square test between age group and components of the cardiovascular
health score <0.05.
Source: Authors.
5
poor cardiovascular score, 0.58 (95%CI: 0.48- self-reported diagnosis of depression, compared
0.70) for ideal vs. intermediate/poor behavioral to having intermediate/poor cardiovascular
score and 0.48 (95%CI: 0.43-0.54) for ideal vs. health. This relationship was significant for both
intermediate/poor biological score (Table 3). the biological, behavioral and cardiovascular
health components, and was maintained even
after adjusting for sociodemographic variables.
Discussion In relation to the variables that make up the
cardiovascular health score and the analysis of
The study showed that having ideal cardiovas- the association with the diagnosis of depression,
cular health was inversely associated with a it is known that some studies have already shown
6
Pinheiro MLSP et al
Table 3. Unadjusted and adjusted odds ratios (OR) of depression in relation to cardiovascular health scores.
National Health Survey, 2019.
Not adjusted Model 1
Depression
OR (95%CI) OR (95%CI)
Ideal biological score*** vs. Bad 0.48 (0.43-0.53)** 0.48 (0.43-0.54)**
Behavioral score**** ideal vs. Bad 0.58 (0.48-0.70)** 0.58 (0.48-0.70)**
Ideal cardiovascular score***** vs. Bad 0.53 (0.48-0.59)** 0.53 (0.48-0.59)**
Notes: 95%CI: 95% Confidence Interval. Model 1: adjusted for sociodemographic values (gender, race, age, education and
marital status). **p<0.01. ***Sum of factors: smoking, dyslipidemia, hypertension and diabetes, ideally ≥3 factors. ****Sum of
factors: BMI, smoking, diet and physical activity, ideally ≥3 factors. *****Sum of the 7 factors, ideally ≥4 factors.
Source: Authors.
the effects of physical exercise in the prevention tective factors for cardiovascular diseases, and
and treatment of depression46,47, as well as the the inverse association with depression found
effects of good nutrition20, controlled blood in this study, is consistent with national and in-
pressure24,25 and controlled blood glucose26. The ternational evidence10,25,30. A prospective study
components of the cardiovascular health score of 732 Finnish female employees who were not
showed direct and significant associations be- initially depressed assessed ideal cardiovascular
tween unhealthy behaviors (smoking, physical health metrics by means of physical examina-
inactivity) and a diagnosis of depression48, cor- tion and laboratory tests, medical history and
roborating the findings of this study. self-assessment, and showed a higher risk of de-
There is evidence that there is a bidirectional pressive symptoms in those with poor/interme-
association between CVD and depression. The diate cardiovascular health25.
association of these disorders arises because of a In Dallas, Texas, another prospective epide-
series of shared factors; biological and behavior- miological study was carried out between 1987
al mechanisms and risk factors10,14. Individuals and 1998 with 5,510 participants in the Aerobics
with CVD are two to three times more likely to Center Longitudinal Study. The authors con-
develop depression49, and individuals with de- cluded that the ideal components of cardiovas-
pression are more likely to develop CVD49,50. cular health show an inverse relationship with
Although there are few studies on the mech- depressive symptoms, which was significant
anisms involved in the cardiovascular health in the case of cardiovascular health behaviors,
score and the development of depression, there but not for cardiovascular health factors such
are studies on the mechanisms of isolated score as total cholesterol, blood pressure and fasting
variables and the predisposition to develop de- glycemia30.
pression18,20-24,51. One study showed that a lower Additionally, in agreement with the findings
intake of FV is related to depressive symptoms52, of this study, Elsa-Brasil, a multicenter cohort
due to the influence of minerals, vitamins, ami- study of 15,105 active or retired civil servants
no acids, phytochemicals and antioxidant com- aged 35 to 74, showed that poor cardiovascular
pounds, which in low concentrations interfere health precedes the development of depression.
with inflammatory markers, oxidative stress and In addition, adults without a diagnosis of de-
arterial stiffness53. pression were followed up for an average of 3
In this study, consumption of the ideal years and 8 months, and it was found that poor
diet was low in relation to 2 important indica- cardiovascular health tripled the risk of depres-
tors, FVG and fish, which showed low preva- sion10.
lence (7.23% and 24.44%, respectively) (data It should be noted that depression is one
not shown). For this reason, public policies of the conditions that contributes most to the
are needed to enable greater access to healthy global burden of mental health-related diseases
food and thus promote the fight against chronic in the world55, despite its underdiagnosis56. Due
non-communicable diseases (CNCDs) and con- to its high prevalence, repercussions on general
tribute to achieving sustainable development health and psychosocial impact, it constitutes a
goals54. serious public health problem57.
It should be noted that the ideal cardiovas- Nowadays, the prevalence of unhealthy life-
cular health score, made up of potential pro- style habits and depressive symptoms may be
7
the use of this score in the clinical practice of score can contribute to comprehensive individ-
health professionals could help raise awareness ual and collective health care, through interven-
of the importance of healthy lifestyle habits tions that promote the prevention of diseases
aimed at promoting health and preventing ill- and the investigation and screening of chronic
nesses. In addition, the implementation of the conditions.
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