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Sub-Topic: Bacterial Shape, Size, and Arrangement (Morphology)
Part 1: Bacterial Size
 irst, let's appreciate how small these organisms are. Bacteria are measured inmicrometers
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(µm).
   1 micrometer (µm) = 1/1,000,000 of a meter.
 ●
 ● Most medically important bacteria are about0.2 to2.0 µmin diameter or width and1.0
       to 10.0 µmin length.
  ● To give you perspective, a single red blood cell is about 7 µm in diameter. So you could
        line up several bacteria across one of your own blood cells!
Part 2: Bacterial Shapes (Morphology)
Bacteria are classified based on their basic shape. Think of these as the main families.
 1. C   occi (singular: Coccus)
          ○ Meaning:From the Greek wordkokkos, meaning "berry."
           ○ Description:These are spherical or oval-shaped bacteria.
  2. Bacilli (singular: Bacillus)
            ○ Meaning:From the Latin wordbaculus, meaning "rod"or "stick."
             ○ Description:These are rod-shaped bacteria.
   3. Spiral Forms
              ○ Description:These are bacteria that are curved orhelical. This group has a few
                   important sub-types that you must know.
                     ■ Vibrio:A curved or comma-shaped rod. It has lessthan one complete twist.
                      ■ Spirillum:A rigid, helical bacterium with two ormore curves. It moves using
                            external flagella.
                       ■ Spirochete:A flexible, helical bacterium that lookslike a corkscrew. It has a
                             unique internal flagella system for movement.
Part 3: Bacterial Arrangements
 his is where it gets really useful. How bacteria group themselves after they divide gives us
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major clues to their identity. The arrangement is determined by theplane of cell division.
A. Arrangements of Cocci
Imagine a single spherical bacterium dividing.
 ● I f it divides in one plane:It can form pairs or chains.
          ○ Diplococci (Pairs):The cocci remain in pairs afterdivision.
                    ■ Key Medical Examples:
                                   ■ Neisseria gonorrhoeae(causes gonorrhea). They aretypically kidney-bean
                                         shaped.
                                    ■ Streptococcus pneumoniae(a major cause of pneumoniaand meningitis).
                                          They are lancet-shaped or flame-shaped.
           ○ Streptococci (Chains):The cocci divide repeatedlyin one plane and remain
                   attached, forming a chain.
                     ■ Analogy:Think of aStrapor aStringof pearls.
                      ■ Key Medical Example:Streptococcus pyogenes(causesstrep throat and
                               rheumatic fever).
  ● If it divides in two planes at right angles:It formsgroups of four.
            ○ Tetrads (Groups of 4):
                       ■ Key Medical Example:Micrococcusspecies.(Often non-pathogenic,found on
                                skin).
   ● If it divides in three planes at right angles (like cutting a cube):It forms cubical
         packets of eight.
             ○ Sarcinae (Packets of 8):
                        ■ Key Medical Example:Sarcina ventriculi.
    ● If it divides in multiple planes, randomly:It formsgrape-like clusters.
              ○ Staphylococci (Clusters):
                         ■ Analogy:Think of aStaffof grapes.
                          ■ Key Medical Example:Staphylococcus aureus(causesboils, abscesses, and
                                 toxic shock syndrome).
        linical Point:This is incredibly useful in the lab.If a doctor gets a report of
       C
       "Gram-positive cocci in clusters" from an abscess, they immediately suspect
        Staphylococcus aureusand can start appropriate treatmenteven before the final
         identification is ready. If the report says "Gram-positive cocci in chains" from a
          throat swab, they'll think ofStreptococcus pyogenes.
B. Arrangements of Bacilli
 ods generally divide only across their short axis (a process called transverse fission), so they
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have fewer arrangements than cocci.
 ● C   occobacilli:These are short, plump rods that looklike a mix between a coccus and a
        bacillus.
         ○ Key Medical Example:Haemophilus influenzae,Brucellaspp.
  ● Diplobacilli (Pairs):Two rods paired together.
   ● Streptobacilli (Chains):Rods arranged in chains.
 ● P
      alisades (Fence-like):The rods line up side-by-side, like a picket fence. This is also
     called a "coryneform" arrangement.
      ○ Key Medical Example:Corynebacterium diphtheriae(causesdiphtheria). The
           bacteria look like "Chinese letters" or a V-shape under the microscope because they
            snap back on each other after division. This is a classic exam description.
C. Pleomorphism
 ome bacteria don't have a single, fixed shape. They can vary in shape and size even within a
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single culture. This property is calledpleomorphism.
 ● A
      classic example isMycoplasma, which has no cellwall at all, so it's completely
     pleomorphic and can look like anything.
Summary Table: Bacterial Morphology & Arrangement
(This table blends information from Sastry and Murray for your high-yield review)
 Shape              Arrangement       Description        ey Medical
                                                              K                     xam Nugget
                                                                                   E
                                                              Example            / Clinical
                                                                                    Pearl
 Cocci               iplococci
                      D                   Cocci in pairs.    treptococcus
                                                              S                     . pneumoniae
                                                                                   S
                      (Pairs)                               pneumoniae,      are
                                                               Neisseriaspp.    lancet-shaped.
                                                                                     Neisseriaare
                                                                                      kidney-bean
                                                                                       shaped and
                                                                                        are
                                                                                         Gram-negative
                                                                                          .
                       treptococci
                      S                    occi in chains
                                          C                    treptococcus
                                                              S                     eeing chains
                                                                                   S
                      (Chains)          of varying        pyogenes           of
                                           lengths.          (Group A           Gram-positive
                                                                Strep)             cocci is highly
                                                                                      suggestive of a
                                                                                       Streptococcal
                                                                                        infection.
                       taphylococci
                      S                    occi in
                                          C                    taphylococcu
                                                              S                     eeing clusters
                                                                                   S
                      (Clusters)        irregular,        s aureus           of
                              rape-like
                             g                                      ram-positive
                                                                   G
                             clusters.                           cocci is highly
                                                                    suggestive of a
                                                                     Staphylococca
                                                                      l infection
                                                                       (e.g., abscess).
            Tetrads         occi in
                             C                  icrococcus
                                               M                    ften
                                                                   O
                             square groups   spp.              considered a
                              of four.                            contaminant
                                                                     from the skin
                                                                      in clinical
                                                                       samples.
            Sarcinae        occi in
                             C                 Sarcinaspp.      ot commonly
                                                                   N
                             cubical                             pathogenic.
                              packets of
                               eight.
Bacilli   Coccobacilli    ery short,
                             V                  aemophilus
                                               H                    . influenzaeis
                                                                   H
                             plump rods.     influenzae,     a major cause
                                                Brucella          of meningitis
                                                                     and
                                                                      pneumonia,
                                                                       especially in
                                                                        children.
             alisades
            P                 ods arranged
                             R                  orynebacteri
                                               C                    lassic
                                                                   C
            (Coryneform)   side-by-side    um diphtheriae    description is
                              or at sharp                         "Chinese letter
                               angles.                             pattern" or
                                                                      "club-shaped."
                                                                       (High-yield
                                                                        for
                                                                         INICET/NEET
                                                                          PG)
Spiral    Vibrio          urved,
                             C                 Vibrio cholerae    he cause of
                                                                   T
                             comma-shape                         cholera, a
                              d rod.                              severe
                                                                     diarrheal
                                                                                     disease.
                      Spirillum          igid, helical
                                          R                     pirillum minus
                                                               S                      ot as
                                                                                     N
                                          shape with         (causes a type      clinically
                                           external           of rat-bite         common as
                                            flagella.          fever)              the others.
                      Spirochete         lexible,
                                          F                     reponema
                                                               T                      heir unique
                                                                                     T
                                          corkscrew          pallidum            endoflagella
                                           shape with         (Syphilis),         allows them to
                                            internal           Borrelia(Lyme     move in a
                                             flagella.          Disease)            corkscrew
                                                                                         motion,
                                                                                          enabling them
                                                                                           to drill through
                                                                                            viscous tissue.
                                                                                             (High-yield
                                                                                              concept)
For Your Exams
Practical Exam (OSPE/Viva)
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 ●      potter:A Gram stain slide is shown.
 ● Examiner:"Describe the morphology of the bacteriayou see on this slide."
  ● Your Ideal Answer:"Sir/Ma'am, on this slide, I cansee[Color, e.g., purple]colored
       organisms, indicating they are[Gram-positive/negative].Their shape is
        [spherical/rod-shaped], and they are arranged in[chains/clusters/pairs].Therefore,
         the morphology is Gram-[positive/negative] [cocci/bacilli]in
          [chains/clusters/pairs]."
           ○ Example: "Gram-positive cocci in clusters."
Entrance Exams (MCQs)
 CQ 1 (NEET PG Style): A Gram stain from a skin abscess reveals purple, spherical bacteria
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arranged in irregular clusters. Which of the following organisms is the most likely cause?
 A. Streptococcus pyogenes
  B. Neisseria meningitidis
   C. Staphylococcus aureus
    D. Corynebacterium diphtheriae
     Answer: C. (The keywords are purple [Gram-positive], spherical [cocci], and clusters. This
      classic description points directly to Staphylococcus).
 CQ 2 (INICET Style): A microbiologist observes a bacterium with a flexible, helical shape that
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exhibits a corkscrew-like motility. This motility is most likely due to the presence of:
 A. Peritrichous flagella
  B. A single polar flagellum
   C. Axial filaments (Endoflagella)
    D. Pili
     Answer: C. (The description of a flexible, helical bacterium with corkscrew motility is classic
      for a spirochete. Their unique motility is provided by their internal flagella, known as axial
       filaments or endoflagella).