Vitamins
Dr.Sivaraman Dhanasekaran
Department of Biotechnology
School of Energy Technology
                              1
         UNIT 1
                                         Vitamins
• Vitamins are organic compounds that are essential for normal growth, development, and
  metabolic processes in the body.
• They are required in small amounts and typically must be obtained from the diet because
  the body either does not produce them at all or does not produce them in sufficient
  quantities.
                                     13 essential vitamins
          Water-soluble                                         Fat-soluble
      Vitamin C and the B vitamins                            Vitamins A, D, E, and K
               Fat -soluble                                                   Water-soluble
                                      13 Vitamins and Its Classification
•   Vitamin A (Retinol, Retinal, Retinoic acid)            •   Vitamin B1 (Thiamine)
•   Vitamin D (Calciferol)                                 •   Vitamin B2 (Riboflavin)
•   Vitamin E (Tocopherols and Tocotrienols)               •   Vitamin B3 (Niacin)
•   Vitamin K (Phylloquinone and                           •   Vitamin B5 (Pantothenic Acid)
Menaquinones)                                              •   Vitamin B6 (Pyridoxine, Pyridoxal, Pyridoxamine)
                                                           •   Vitamin B7 (Biotin)
                                                           •   Vitamin B9 (Folate or Folic Acid)
                                                           •   Vitamin B12 (Cobalamin)
                                                           •   Vitamin C (Ascorbic Acid)
                                               Key Difference
              Vitamins                                                       Vitamers
Vitamins are a group of organic compounds                       Different chemical compounds that belong
 that are essential for normal physiological                      to the same vitamin family and exhibit
                  functions                                              similar biological activity.
                                                                  Vitamin A Vitamers: Includes retinol,
Vitamin A, Vitamin C, Vitamin D, Vitamin E                             retinal, and retinoic acid
                          Vitamins that the body can
                                  synthesize
      Vitamin K
     Gut bacteria
    Large intestine                                    Calcium and phosphorus
                                                             absorption
Blood clotting and bone
        health.                                          Bone health, immune
                                                               function
                                      Vitamins from Other Sources
            Vitamin C                           Vitamin B                        Vitamin E
• Citrus fruits (oranges, lemons,                                      • Vegetable oils (sunflower,
                                      • Bananas, Whole grains,           safflower, and wheat germ
  grapefruits),
                                        legumes, nuts, Egg, Rice,
• Strawberries, kiwi, bell peppers,                                      oil), nuts (almonds,
                                        Spinach and seeds.               hazelnuts),
  broccoli,
                                                   Vitamin A
                                       • Carrots, sweet potatoes and
                                         spinach
                                     Energy Production
                                                         Co- Enzymes
• B Vitamins: Vitamins such as
  B2 (riboflavin), B3 (niacin), B5
  (pantothenic acid), and B7
                                                         Citric Acid Cycle
  (biotin)
•   Act as coenzymes in metabolic                        ATP Production
    pathways, such as the Krebs
    cycle, which is essential for
    ATP production, the primary
    energy currency of the body.
                            Blood
Vitamin B12 (Cobalamin)
    and B9 (Folate)                     Vitamin K
                                    Synthesis of clotting
 Red blood cell formation                 factors
      Formation of                  Preventing excessive
      Haemoglobin                        bleeding
    Carrying oxygen
  throughout the body
                          Immune System Support &
                              Brain Function
     Vitamin C                     Vitamin E                 B Vitamins
 Growth and repair of                                      Neurotransmitter
                                    Antioxidant
       tissues                                                synthesis
                             Healthy skin and eyes and
Production and function                                  Brain development and
                               supports the immune
  of white blood cells                                      Memory function
                                      system
 Supports the immune
       system
                          Cell Growth and Development
                                  B1 (thiamine) and
      Vitamin A                  Vitamin B9 (Folate)           Vitamin D
                                                         Absorption of calcium and
      Rhodopsin                    DNA synthesis
                                                               phosphorus
   Vision in low-light           Cell division and the       Bone growth and
       conditions                development of the           development
                                  nervous system.
Vision, immune function
             Primary functions and the deficiency of
                            Vitamins
 Vitamin A           Vision, immune function,          Night blindness, xerophthalmia
                            skin health,                     (dry eyes), Dry skin
                                                   Scurvy (bleeding gums, joint
Vitamin C            Antioxidant protection,
                                                    pain, swollen gums, poor
                        immune support
                                                     wound healing, fatigue)
                                                     Rickets in children (bone
Vitamin D           Calcium absorption, bone
                                                   deformities), osteomalacia in
                             health
                                                               adults
                 Primary functions and the deficiency of
                                Vitamins
   Vitamin K               Blood clotting, bone
                                                                Increased bleeding
                                  health
  Vitamin E              Antioxidant protection,           Nerve and muscle damage,
                            immune support                      vision problems
Vitamin B9/B12                                             Anemia (fatigue, weakness,
                         Blood Cell Production
                                                                   pale skin)
Additional information on Vitamins
  Vitamin                                                    Deficiency disease(s)                Food sources
               Vitamers (incomplete)         allowances
                                                                                      from animal origin as Vitamin A / all-
                                                                                      trans-Retinol: Fish in general, liver
                                                                                      and dairy products;
            all-trans-Retinol, Retinals,
            and                                                                       from plant origin as provitamin A /
            alternative provitamin A-                                                 all-trans-beta-carotene: orange, ripe
            functioning Carotenoids                        Night                      yellow fruits, leafy vegetables,
            including all-trans-beta-                      blindness, hyperkeratosis, carrots, pumpkin, squash, spinach
Vitamin A   carotene                       900 µg/700 µg   and keratomalacia
                                                                                    Eggs, liver, certain fish species such
            Cholecalciferol (D3), Ergocal                                           as sardines, certain mushroom
Vitamin D   ciferol (D2)                  15 µg/15 µg      Rickets and osteomalacia species such as shiitake
                                                           Deficiency is very rare;
                                                           mild hemolytic anemia in Many fruits and vegetables, nuts and
Vitamin E   Tocopherols, Tocotrienols      15 mg/15 mg     newborn infants          seeds, and seed oils
            Phylloquinone, Menaquinon AI:                                             Leafy green vegetables such as
Vitamin K   es                        110 µg/120 µg        Bleeding diathesis         spinach; egg yolks; liver
                                                                                                   Pork, wholemeal grains, brown
                                                                 Beriberi, Wernicke-Korsakoff      rice, vegetables, potatoes, liver,
Vitamin B1    Thiamine                         1.2 mg/1.1 mg     syndrome                          eggs
                                                                 Ariboflavinosis, glossitis, angular Dairy products, bananas, green
Vitamin B2    Riboflavin                       1.3 mg/1.1 mg     stomatitis                          beans, asparagus
                                                                                                     Meat, fish, eggs, many
              Niacin, Niacinamide, Nicotinamid                                                       vegetables, mushrooms, tree
Vitamin B3    e riboside                       16 mg/14 mg       Pellagra                            nuts
Vitamin B5    Pantothenic acid                 5 mg/5 mg         Paresthesia                         Meat, broccoli, avocados
              Pyridoxine, Pyridoxamine, Pyridox 1.3–1.7 mg/1.2– Anemia,[17] Peripheral             Meat, vegetables, tree nuts,
Vitamin B6    al                                1.5 mg          neuropathy                         bananas
Vitamin B7                                                                                         Raw egg yolk, liver, peanuts, leafy
/ Vitamin H   Biotin                           AI: 30 µg/30 µg Dermatitis, enteritis               green vegetables
                                                                 Megaloblastic anemia and
                                                                 deficiency during pregnancy is
                                                                 associated with birth defects,    Leafy vegetables, pasta, bread,
Vitamin B9    Folates, Folic acid             400 µg/400 µg      such as neural tube defects       cereal, liver
              Cyanocobalamin, Hydroxocobala
              min, Methylcobalamin, Adenosylc
Vitamin B12   obalamin                        2.4 µg/2.4 µg      Vitamin B12 deficiency anemia[19] Meat, poultry, fish, eggs, milk
Vitamin C     Ascorbic acid                    90 mg/75 mg       Scurvy                            Many fruits and vegetables, liver
Thanks