UNIVERSITY OF MADRAS
B.Sc. DEGREE PROGRAMME IN MICROBIOLOGY
SYLLABUS WITH EFFECT FROM 2023-2024
Marks
Credits
Subject Inst.
Subject Name Category L T P S
Code Hours CIA Exter- Total
nal
Bacteriology And
336C5A Core Course IX Y - - - 4 5 25 75 100
Mycology
Course Objectives
CO1 Understand the role of normal flora and pathogenic microbes of various diseases and clinical
microbiological techniques.
CO2 Basic knowledge about Gram positive pathogenic bacteria and their epidemiology
CO3 Acquire knowledge about Gram negative pathogenic bacteria and nosocomial infections
CO4 Comprehensive knowledge about medically important, its classification and its significance
CO5 Gain knowledge about the general characteristics and mode of action of various antibacterial
agents
Unit Details No.of Course
Hours Objectives
I History, Classification of Medically Important Microbes, Koch’s, and 12 CO1
River’s postulates-A brief account on the normal microbial flora of
the healthy human body – Host-pathogen interactions: Definitions of
infection, invasion, primary and opportunistic pathogens,
pathogenicity, virulence, toxigenicity, carriers, endemic, epidemic,
pandemic diseases and epidemiology – putative virulence factors of
human pathogens –infectious disease cycle. Collection and transport
of clinical specimens for bacterial and fungal infections.
II Medically Important Gram Positive infections - Causative agent, 12 CO2
clinical symptoms, pathogenesis, mode of transmission, prevention
and treatment of the following bacterial diseases (a) Streptococcal
infections (Streptococcus pyogenes, Streptococcus faecalis), (b)
Staphylococcal infections (Staphylococcus aureus), (c) Tetanus
(Clostridium tetani)(d) Diphtheria (Corynebacterium diphtheriae) (e)
Anthrax (Bacillus anthracis) (f) Tuberculosis (Mycobacterium
tuberculosis), (g) Leprosy (Mycobacterium leprae).
III Medically Important Gram-Negative infections - Causative agent, 12 CO3
clinical symptoms, pathogenesis, mode of transmission, prevention,
and treatment of the following bacterial diseases (a) Meningitis
(Streptococcus pneumoniae, Neisseria meningitidis) (b) typhoid
(Salmonella typhi, Salmonella paratyphi) (c) cholera (Vibrio
cholerae) (d) bacillary dysentery (Shigella dysenteriae); Sexually
Transmitted disease (Syphilis–Treponema pallidum. Gonorrhoea -
Neisseria gonorrhoeae); Nosocomial infections – definition,
importance, and their control (Pseudomonas aeruginosa).
IV Medically Important Fungi - Classification of medically important 12 CO4
fungi; Superficial mycoses: Pityriasis versicolor; Tinea nigra; Piedra.
Cutaneous mycoses: Microsporum spp., Trichophyton spp., and
UNIVERSITY OF MADRAS
B.Sc. DEGREE PROGRAMME IN MICROBIOLOGY
SYLLABUS WITH EFFECT FROM 2023-2024
Epidermophyton floccosum. Subcutaneous mycoses:
Chromoblastomycosis; Sporotrichosis; Systemic Mycoses -
Blastomycosis; Histoplasmosis; Opportunistic Infections -
Candidiasis; Cryptococcosis; Zygomycosis; Mycotoxins: Aflatoxin
V Antimicrobial agents -General characteristics and mode of action of 12 CO5
Antibacterial agents: Modes of action with an example for each:
Inhibitor of nucleic acid synthesis; Inhibitor of cell wall synthesis;
Inhibitor of cell membrane function; Inhibitor of protein synthesis;
Inhibitor of metabolism. Antifungal agents: Mechanism of action of
Amphotericin B, Griseofulvin.
Total 60
Course Outcomes
CO On completion of this course, students will;
CO1 Understand the importance of normal flora of human body and acquire PO1, PO3, PO5,
knowledge on the process of infectious disease. PO7, PO10, PO11
CO2 Explain the various bacterial pathological events during the PO1, PO3, PO5,
progression of an infectious disease, and apply the underlying PO7, PO10, PO11
mechanisms of spread of disease and its control.
CO3 Compile a list of disease-causing bacteria and compare their modes of PO1, PO3, PO5,
infection, symptoms, diagnosis and treatment. PO7, PO10, PO11
CO4 Comprehend human-fungal interaction, which can be applied to obtain PO1, PO3, PO5,
in-depth knowledge on fungal diseases and the mechanism behind the PO7, PO10, PO11
disease process.
CO5 Explain the types of mycoses caused in humans and categorize the PO1, PO3, PO4,
modes of infection, pathogenesis, and treatment with introduction to PO5,PO6,
mycotoxins. PO7,PO9, PO10
Text Books
Tom Parker, M. Leslie H. Collier. (1990). Topley&Wilson’s Principles of
1
Bacteriology, Virology and Immunity,8th Edition. London: Edward Arnold.
Greenwood, D., Slack, R.B. and Peutherer, J.F. (2012) Medical Microbiology, 18thEdition.
2
Churchill Livingstone, London.
Finegold, S.M. (2000) Diagnostic Microbiology, 10th Edition. C.V. Mosby Company, St.
3
Louis.
Ananthanarayanan, R. and JayaramPanicker C.K. (2020) Text book of Microbiology.
4
Orient Longman, Hyderabad.
JagdishChander (2018). Textbook of Medical Mycology, 4th edition, Jaypeebrothers
5
medical publishers.
References Books
1 Gerhardt, P., Murray, R.G., Wood, W.A. and Kreig, N.R. (Editions) (1994) Methods for
General and Molecular Bacteriology. ASM Press, Washington, DC.
2 Kevin Kavanagh, (2018). Fungi Biology and Applications 3rd Edition. Wiley Blackwell
publishers.
3 C.J. Alexopoulos, C.W. Mims, M. Blackwell, (2007). Introductory Mycology, 4th edition.
Wiley publishers.
UNIVERSITY OF MADRAS
B.Sc. DEGREE PROGRAMME IN MICROBIOLOGY
SYLLABUS WITH EFFECT FROM 2023-2024
4 A.J. Salle (2007). Fundamental principles of bacteriology, fourth edition, Tata McGraw-
Hill Publications.
5 Christopher C. Kibbler ,Richard Barton,Neil A. R. Gow, Susan Howell,Donna M.
MacCallum, Rohini J. Manuel (2017). Oxford Textbook of Medical Mycology. Oxford
University Press.
Web Resources
1 http://textbookofbacteriology.net/nd
2 https://microbiologysociety.org/members-outreach-resources/links.html
3 http://mycology.cornell.edu/fteach.html
4 https://www.adelaide.edu.au/mycology/
5 https://www.isham.org/mycology-resources/mycological-links
Methods of Evaluation
Continuous Internal Assessment Tests 25 Marks
Internal Assignments
Evaluation Seminars
Attendance and Class Participitation
External End Semester Examination 75 Marks
Evaluation
Total 100 Marks
Methods of Assessment
Recall (KI) Simple definitions, MCQ, Recall steps, Concept definitions
Understand /
Comprehend MCQ, True/False, Short essays, Concept explanations, Short summary or overview
(K2)
Application Suggest idea/concept with examples, Suggest formulae, Solve problems, Observe,
(K3) Explain
Analyse Problem-solving questions, Finish a procedure in many steps, Differentiate between
(K4) various ideas, Map knowledge
Evaluate
Longer essay/ Evaluation essay, Critique or justify with pros and cons
(K5)
Create (K6) Check knowledge in specific or offbeat situations, Discussion, Debating or
Presentations
Mapping with Programme Outcomes
CO/PO PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11
CO1 S S S S M S
CO2 S S S S M S
CO3 S S S S M S
CO4 S S S S M S
CO5 S S M S M S S M
