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November Recalls 2022: Smoking Induces

The document contains a series of medical recall questions and answers related to drug metabolism, pharmacology, and treatment protocols. It covers various topics such as drug interactions, side effects, and specific medications used for conditions like hypertension, hyperlipidemia, and infections. Additionally, it includes calculations related to drug dosages and pharmacokinetics, as well as questions about vaccines and their contraindications.
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0% found this document useful (0 votes)
41 views16 pages

November Recalls 2022: Smoking Induces

The document contains a series of medical recall questions and answers related to drug metabolism, pharmacology, and treatment protocols. It covers various topics such as drug interactions, side effects, and specific medications used for conditions like hypertension, hyperlipidemia, and infections. Additionally, it includes calculations related to drug dosages and pharmacokinetics, as well as questions about vaccines and their contraindications.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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November recalls 2022

❓Smoking induces:-

CYP1A2✔️

CYP3A4

CYP2DC

❓ Ibuprofen and celecoxib metabolized by:-

CYP1A2

CYP2C9✔️

CYP2C19

CYP2D6

CYP3A4

CYP2C9

CYP2C19

Codeine metabolized by :-

CYP1A2

CYP2D6✔️

CYP2C9

CYP2C19

CYP3A4

❓ Rivaroxaban metabolized by:-

CYP1A2
CYP2C9

CYP2C19

CYP2D6

CYP3A4✔️

❓ Irbesartan and losartan metabolized by:-

CYP1A2

CYP2C9✔️

CYP2C19

CYP3A4

CYP2D6

❓ Amiodarone metabolised by:-

CYP1A2

CYP2C9

CYP2C19

CYP3A4✔️

CYP2D6

[12:36 AM, 12/12/2022] Mustafa R. Wally: Answers:-

❓ Vitamin with steroid structure.

D✔️

K
❓ Agent without active metabolite.

Morphine

Ramipril

Diazepam

Nifedipine✔️

❓ Atropine and diphenoxylate least likely to cause:-

Dry mouth

urinary retention

sedation

bronchospasm✔️

❓ bluish discoloration of nails

carbon monoxide toxicity

apnea

hypochondriasis

cyanosis✔️

❓ Storage of glyceryl trinitrate (GTN):-

warm place

refrigerator

amber color bottle✔️

plastic bottle with cap


[12:36 AM, 12/12/2022] Mustafa R. Wally: Structures : celebrex and amphetamine , niacin ,

Some quest about keto acidosis, the active metabolite and receptors and asthma , diabetes

Acetzolamide and spironlacton many questions side effects and use

Same as the last session 2d6 and 1a2

Q 165

Enzyme receptor

Uric crystals

Tricyclic one question

Also there is a question .. Na meta bisulfite .. is not SAA

Calcitriol is Vit D analog used for Hypothy+2ry Hyperthyroidism

Calcitonin used in Hyperthyroidism

[12:36 AM, 12/12/2022] Mustafa R. Wally: Penicillin with longest duration of action

Nicotinic acid

Warfarin toxicity

Hcl secreted by with cell

Read haloperidol

Digitalis warfarin many question about them

Penicillin resistance to Penicillinase, acid resistance

Read about uti drug

TCS side effect


Drug not used in heat failure

Least side effect of beta blocker

Tradiv dyskancya

Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence

[12:36 AM, 12/12/2022] Mustafa R. Wally: Lefunomide 1 question

Regarding dose and side effect

Organophosphate poison

Penicillin with longest duration of action

Nicotinic acid

Warfarin toxicity

Hcl secreted by with cell

Read haloperidol

Digitalis warfarin many question about them

Penicillin resistance to Penicillinase, acid resistance

Read about uti drug

TCS side effect

Drug not used in heat failure

Least side effect of beta blocker

Tradiv dyskancya

Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence

These are from Australia 7 th Nov exam

I will keep on posting when I rember

Focus on Digitalis warfarin caliromathcyn amino glucoside side effect and toxicology surfacely

Don't go deep

Couple of questions from vaccine read detail about conjugated , and li…

[12:36 AM, 12/12/2022] Mustafa R. Wally: I have around 10,15 Q from july 22 and

1- Aspirin Antithrombin moa

2- Trimpethoprim Moa

3- Clotrimazole active against agent P.juvuni

4- Tca least Se

5- Atropine Therapeutic effect


6- More potent among corticosteroids ( Dexa )

7- Least Se of aspirin ( Urticaria)

8- Antipsychotics Moa

9- Monosaccharides Example

10- immunosuppression --- Cyclosporine

12- Q 2,3 of july 22 ,

[12:36 AM, 12/12/2022] Mustafa R. Wally: Todays

Live attenuated vaccine

Non conjugated vaccine

Conjugated vaccine

Lanolin clculation

Chlorhexidine .05% calc

Which shouldnt be given with brady arrythmia in glaucoma (latamo, BB)

AB resistant in australia clarithro

Pressure of blood important in the GF process (hydrostatic, osmotic, intatubular)

Which is correct? Frusimide proximal tubule, HCTZ distal tubule, osmotic diuretic Glomerulus

Buffer sol used to prepare intranasal prep

CI in closed angle glaucoma

HCL is secreted by (parietal cells, proton cells)

[12:36 AM, 12/12/2022] Mustafa R. Wally: A solution contain 14% w/v of drug with molecular
weight 50( value not sure). A gastric lavage solution containing 1 L of 0.1 M of the drug is required.
How much of initial drug solution will you need?

[12:36 AM, 12/12/2022] Mustafa R. Wally: Spironolactone interact with a medicine whis is given for
acne?

In options gave

1- Tramadol

2- Meloxicam

3- Amitryptaline

4- cannot remember

[12:36 AM, 12/12/2022] Mustafa R. Wally: Calculations


1- Metronidazole 101.3

2- 1.6 t1/2 initial dose 4 to reach 1 —> 2.3

3- Alligation 500

4- Drug A 480 Drug B 350

5- Lanoline 72%

6- VD —> 40 l

[12:36 AM, 12/12/2022] Mustafa R. Wally: 1- indicated in oesphageal ulcer by driving acidity away
from the ulcer

A-PPI

B-Sucralfate

C-H2 blocker

D-Metoclopramide

2- Male non gonococchal pyelonephritis

a-Tetracyclinr

B-Azithromycin

C-Amoxacillin

D-Trimethoprim

3- Right site of action-drug combination

A-Furosemide-proximal tubule

B-Spironolactone-loop of henle

C-Mannitol-glomerulus

D-Thiazide-istal tubule

4-Type of raditiaon used in sterilization


A-alpha

B-beta

C-gamma

5-usually used in active TB

A-chest X ray

B-Tunurculin Mantoux Test

[12:36 AM, 12/12/2022] Mustafa R. Wally: 29- not True about haemrrhoids therapy

A- hemorrhoids in preganacy should be treated agressively to prevent recurrence after delivery

B- although bleeing is common and not necessarily serious, all cases should be referred to general
paractitioner

C- formulas to treat haemrrhoids contain local anesthetics, astringents and corticosteroids

D- for trating underlying constipation, a short course of stimulant laxative and stool softeners maybe
used

30- least to affect rectal absorption of a suppository

A- partition coefficient of the drug

B- lipophilicity of medication

C-position of suppository in rectum

D-hydration of the patient

[12:36 AM, 12/12/2022] Mustafa R. Wally: 31- to treat enterobiasis

A-metronidazole

B-tenidazole

[12:36 AM, 12/12/2022] Mustafa R. Wally: 32- not an antidepressant

A-Fluoxetine

B-Sertraline

C-Atomoxetine

D-Doxepin
33- have an active metabolite

A- Phenytoin

B- Lithium

C- Temazepam

D- Amitriptylline

34- Least likley to need renal dose adjustment

A- lithium

B- Methotrexate

35- least factor to consider in Aminoglycosides nephrotoxicity

A- age of patient

B- Frequency of dosing (not sure of the wording)

C- Duration of therapy

D- Co-adminsitration with Ciproflxacin

36- antiplatelet mechanism of Aspirin

A-inhibit Cox

B-inhibit prostacyclin

[12:36 AM, 12/12/2022] Mustafa R. Wally: First sign of digoxin poisining?

Patient takes warfarin but no benefit because?

Laxative for opioids?

Vaccine every year male 65yrs?

Gentamycine active for?

Drug distributed with morphine for abuse?

Renal artery stenosis take verapamil but no benefit for htn which add?
Question for eplerenone?

Doxycycline not taken with?

Patient take t4 and has some symptoms? May be call doctor when fever something like this

Substituent for statin in intolerance?

Woman has hf and htn and incontinence need something fot hf? Captopril or another aceis cant
remember , furosemide, something bbs???

Should give for pneumonia in penicillin allergy?

Drug for woman cystitis?

Two questions about colistridium deficile which is wrong in severe cases? Stop antibiotic, isolate
patient, us…

[12:36 AM, 12/12/2022] Mustafa R. Wally: First sign of digoxin poisining?

Patient takes warfarin but no benefit because?

Laxative for opioids?

Vaccine every year male 65yrs?

Gentamycine active for?

Drug distributed with morphine for abuse?

Renal artery stenosis take verapamil but no benefit for htn which add?

Question for eplerenone?

Doxycycline not taken with?

Patient take t4 and has some symptoms? May be call doctor when fever something like this

Substituent for statin in intolerance?

Woman has hf and htn and incontinence need something fot hf? Captopril or another aceis cant
remember , furosemide, something bbs???

Should give for pneumonia in penicillin allergy?

Drug for woman cystitis?

Two questions about colistridium deficile which is wrong in severe cases? Stop antibiotic, isolate
patient, us…

[12:36 AM, 12/12/2022] Mustafa R. Wally: These all are Questions came in my paper 1 & 2 from July
2022 Recalls File:-

Q4.Another Q about amiodarone interaction: a. Inhibits metabolism of 3A4/ A5 substrates


Q6.Metformin dose reduction in which of the following:

a. Renal impairment

Q10.vaccines which is not taken in immunocompromised pts:

a. Yellow fever

Q12.DOC in ttt of hyperlipidaemia for a pt who CANNOT tolerate statins:

a. Cholestyramine

b. Colstipol

c. Ezetemib

Q18.Drug A CBZ 20mg/ml. Required dose 150 mg twice a day.

Drug B Valpoate 200mg/5ml. Required dose 250mg twice a day.

Calculate volume of Drug A and B for 4 weeks supply.

Answer: 420ml Drug A and 350 ml Drug B.

Q19. Least to cause hypokalemia: a.Salbutamol

b.Insulin

c.digoxin

d.Prednisolone

Q21.Nitroglycerin is taken sublinguall…

[12:36 AM, 12/12/2022] Mustafa R. Wally: Then vaccine which are not conjugated

And contraindicated for hiv vaccine I choose live vaccine

Clozapine monitering

Aspirin and acei

Which is not side effect of blocker b

Zolligen syndrome?

Paroxetin least side effect

Glaucoma medicine contraindicated ?


Pencillin resistance 3 questions

Clindamycin is not covering which one?

Shortest acting benzodiape

Smoking inducer which cytochrome

Conc depending killing?antibiotics

Statin memory loss

Digioxin toxicity in respect to potassium

Hypothyroidism which two drugs

Lithium and ammidrone

Acute gout

Treatment

Dose

Polyethylene glycol

Concentrate on vaccine

[12:36 AM, 12/12/2022] Mustafa R. Wally: Structures : celebrex and amphetamine , niacin ,

Some quest about keto acidosis, the active metabolite and receptors and asthma , diabetes

Acetzolamide and spironlacton many questions side effects and use

Same as the last session 2d6 and 1a2

Q 165

Enzyme receptor

Uric crystals

Tricyclic one question

Also there is a question .. Na meta bisulfite .. is not SAA


Calcitriol is Vit D analog used for Hypothy+2ry Hyperthyroidism

Calcitonin used in Hyperthyroidism

Then vaccine which are not conjugated

And contraindicated for hiv vaccine I choose live vaccine

Clozapine monitering

Aspirin and acei

Which is not side effect of blocker b

Zolligen syndrome?

Paroxetin least side effect

Glaucoma medicine contraindicated ?

Pencillin resistance 3 questi…

[12:36 AM, 12/12/2022] Mustafa R. Wally: Calculation:

1-Mmol of Li ( 8.13mmol)

2- Same Q 2 time in paper chlorohexidine ( 8.9ml )

3-0.16---- 0.04 mg calculation 11/2

4- 1.5ppm to prod 6000000ml ( ans : 30ml)


5- Dose ( 100) cp( 2.5) Vd find ( 40L )

6- Digoxin 36 hr find Css 6 days

7-Co ( 200) find con after 24 hr ( ans: 12.503)

8-300 mg Feso4 ( Ans : 60mg)

9- weight ( sensitivity 5 , error 5 ans : 100mg )

10-unioized/ ionized : 100:1

Another Q to PH but easy

11- Elimination 0.173 Find left after 16 hr ( ans ; 64hr )

12-Cpr ch 5 Q ( answr: 936mg )

[12:36 AM, 12/12/2022] Mustafa R. Wally: Today recalls

Ttt of pneoumccocal Jevorici: sulphamethoprim or Metronidazole

Interaction :

X- dipine _ grape fruit Or x- dipine _ statin

Which cause hyponatrimia

amphotricin or CBZ or paroxetine or fludrocortisone

- Tumor lysis syndrome : hyper or hypokalemia

[12:36 AM, 12/12/2022] Mustafa R. Wally: Lefunomide 1 question

Regarding dose and side effect

Organophosphate poison

Penicillin with longest duration of action


Nicotinic acid

Warfarin toxicity

Hcl secreted by with cell

Read haloperidol

Digitalis warfarin many question about them

Penicillin resistance to Penicillinase, acid resistance

Read about uti drug

TCS side effect

Drug not used in heat failure

Least side effect of beta blocker

Tradiv dyskancya

Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence

These are from Australia 7 th Nov exam

I will keep on posting when I rember

Focus on Digitalis warfarin caliromathcyn amino glucoside side effect and toxicology surfacely

Don't go deep

Couple of questions from vaccine read detail about conjugated , and live vaccine

Anaphylaxis which ig

Which vit is toxic to pregnant lady

Mild symptoms on children under 12 dehydration

Which diuretic acts on which part of gf

Drug altering thyroid functin

Have knowledge about lice

Simple question about it

Simple question about psorisis

Not adverse effect of beta blocker

Lithium and amidoron

2 questin about it

What happen in psorosis

Colchicine dose for acute gut


Patient has diclofenac 7 day before for sport injury then doctor prescription ibuprofen what would
you do

Dispense it

Replace it

Ask to use 4 hrs after diclofenace

Dose of colchine in gout

Phenytoin and sartans met. Enzyme

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