November recalls 2022
❓Smoking induces:-
CYP1A2✔️
CYP3A4
CYP2DC
❓ Ibuprofen and celecoxib metabolized by:-
CYP1A2
CYP2C9✔️
CYP2C19
CYP2D6
CYP3A4
CYP2C9
CYP2C19
Codeine metabolized by :-
CYP1A2
CYP2D6✔️
CYP2C9
CYP2C19
CYP3A4
❓ Rivaroxaban metabolized by:-
CYP1A2
CYP2C9
CYP2C19
CYP2D6
CYP3A4✔️
❓ Irbesartan and losartan metabolized by:-
CYP1A2
CYP2C9✔️
CYP2C19
CYP3A4
CYP2D6
❓ Amiodarone metabolised by:-
CYP1A2
CYP2C9
CYP2C19
CYP3A4✔️
CYP2D6
[12:36 AM, 12/12/2022] Mustafa R. Wally: Answers:-
❓ Vitamin with steroid structure.
D✔️
K
❓ Agent without active metabolite.
Morphine
Ramipril
Diazepam
Nifedipine✔️
❓ Atropine and diphenoxylate least likely to cause:-
Dry mouth
urinary retention
sedation
bronchospasm✔️
❓ bluish discoloration of nails
carbon monoxide toxicity
apnea
hypochondriasis
cyanosis✔️
❓ Storage of glyceryl trinitrate (GTN):-
warm place
refrigerator
amber color bottle✔️
plastic bottle with cap
[12:36 AM, 12/12/2022] Mustafa R. Wally: Structures : celebrex and amphetamine , niacin ,
Some quest about keto acidosis, the active metabolite and receptors and asthma , diabetes
Acetzolamide and spironlacton many questions side effects and use
Same as the last session 2d6 and 1a2
Q 165
Enzyme receptor
Uric crystals
Tricyclic one question
Also there is a question .. Na meta bisulfite .. is not SAA
Calcitriol is Vit D analog used for Hypothy+2ry Hyperthyroidism
Calcitonin used in Hyperthyroidism
[12:36 AM, 12/12/2022] Mustafa R. Wally: Penicillin with longest duration of action
Nicotinic acid
Warfarin toxicity
Hcl secreted by with cell
Read haloperidol
Digitalis warfarin many question about them
Penicillin resistance to Penicillinase, acid resistance
Read about uti drug
TCS side effect
Drug not used in heat failure
Least side effect of beta blocker
Tradiv dyskancya
Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence
[12:36 AM, 12/12/2022] Mustafa R. Wally: Lefunomide 1 question
Regarding dose and side effect
Organophosphate poison
Penicillin with longest duration of action
Nicotinic acid
Warfarin toxicity
Hcl secreted by with cell
Read haloperidol
Digitalis warfarin many question about them
Penicillin resistance to Penicillinase, acid resistance
Read about uti drug
TCS side effect
Drug not used in heat failure
Least side effect of beta blocker
Tradiv dyskancya
Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence
These are from Australia 7 th Nov exam
I will keep on posting when I rember
Focus on Digitalis warfarin caliromathcyn amino glucoside side effect and toxicology surfacely
Don't go deep
Couple of questions from vaccine read detail about conjugated , and li…
[12:36 AM, 12/12/2022] Mustafa R. Wally: I have around 10,15 Q from july 22 and
1- Aspirin Antithrombin moa
2- Trimpethoprim Moa
3- Clotrimazole active against agent P.juvuni
4- Tca least Se
5- Atropine Therapeutic effect
6- More potent among corticosteroids ( Dexa )
7- Least Se of aspirin ( Urticaria)
8- Antipsychotics Moa
9- Monosaccharides Example
10- immunosuppression --- Cyclosporine
12- Q 2,3 of july 22 ,
[12:36 AM, 12/12/2022] Mustafa R. Wally: Todays
Live attenuated vaccine
Non conjugated vaccine
Conjugated vaccine
Lanolin clculation
Chlorhexidine .05% calc
Which shouldnt be given with brady arrythmia in glaucoma (latamo, BB)
AB resistant in australia clarithro
Pressure of blood important in the GF process (hydrostatic, osmotic, intatubular)
Which is correct? Frusimide proximal tubule, HCTZ distal tubule, osmotic diuretic Glomerulus
Buffer sol used to prepare intranasal prep
CI in closed angle glaucoma
HCL is secreted by (parietal cells, proton cells)
[12:36 AM, 12/12/2022] Mustafa R. Wally: A solution contain 14% w/v of drug with molecular
weight 50( value not sure). A gastric lavage solution containing 1 L of 0.1 M of the drug is required.
How much of initial drug solution will you need?
[12:36 AM, 12/12/2022] Mustafa R. Wally: Spironolactone interact with a medicine whis is given for
acne?
In options gave
1- Tramadol
2- Meloxicam
3- Amitryptaline
4- cannot remember
[12:36 AM, 12/12/2022] Mustafa R. Wally: Calculations
1- Metronidazole 101.3
2- 1.6 t1/2 initial dose 4 to reach 1 —> 2.3
3- Alligation 500
4- Drug A 480 Drug B 350
5- Lanoline 72%
6- VD —> 40 l
[12:36 AM, 12/12/2022] Mustafa R. Wally: 1- indicated in oesphageal ulcer by driving acidity away
from the ulcer
A-PPI
B-Sucralfate
C-H2 blocker
D-Metoclopramide
2- Male non gonococchal pyelonephritis
a-Tetracyclinr
B-Azithromycin
C-Amoxacillin
D-Trimethoprim
3- Right site of action-drug combination
A-Furosemide-proximal tubule
B-Spironolactone-loop of henle
C-Mannitol-glomerulus
D-Thiazide-istal tubule
4-Type of raditiaon used in sterilization
A-alpha
B-beta
C-gamma
5-usually used in active TB
A-chest X ray
B-Tunurculin Mantoux Test
[12:36 AM, 12/12/2022] Mustafa R. Wally: 29- not True about haemrrhoids therapy
A- hemorrhoids in preganacy should be treated agressively to prevent recurrence after delivery
B- although bleeing is common and not necessarily serious, all cases should be referred to general
paractitioner
C- formulas to treat haemrrhoids contain local anesthetics, astringents and corticosteroids
D- for trating underlying constipation, a short course of stimulant laxative and stool softeners maybe
used
30- least to affect rectal absorption of a suppository
A- partition coefficient of the drug
B- lipophilicity of medication
C-position of suppository in rectum
D-hydration of the patient
[12:36 AM, 12/12/2022] Mustafa R. Wally: 31- to treat enterobiasis
A-metronidazole
B-tenidazole
[12:36 AM, 12/12/2022] Mustafa R. Wally: 32- not an antidepressant
A-Fluoxetine
B-Sertraline
C-Atomoxetine
D-Doxepin
33- have an active metabolite
A- Phenytoin
B- Lithium
C- Temazepam
D- Amitriptylline
34- Least likley to need renal dose adjustment
A- lithium
B- Methotrexate
35- least factor to consider in Aminoglycosides nephrotoxicity
A- age of patient
B- Frequency of dosing (not sure of the wording)
C- Duration of therapy
D- Co-adminsitration with Ciproflxacin
36- antiplatelet mechanism of Aspirin
A-inhibit Cox
B-inhibit prostacyclin
[12:36 AM, 12/12/2022] Mustafa R. Wally: First sign of digoxin poisining?
Patient takes warfarin but no benefit because?
Laxative for opioids?
Vaccine every year male 65yrs?
Gentamycine active for?
Drug distributed with morphine for abuse?
Renal artery stenosis take verapamil but no benefit for htn which add?
Question for eplerenone?
Doxycycline not taken with?
Patient take t4 and has some symptoms? May be call doctor when fever something like this
Substituent for statin in intolerance?
Woman has hf and htn and incontinence need something fot hf? Captopril or another aceis cant
remember , furosemide, something bbs???
Should give for pneumonia in penicillin allergy?
Drug for woman cystitis?
Two questions about colistridium deficile which is wrong in severe cases? Stop antibiotic, isolate
patient, us…
[12:36 AM, 12/12/2022] Mustafa R. Wally: First sign of digoxin poisining?
Patient takes warfarin but no benefit because?
Laxative for opioids?
Vaccine every year male 65yrs?
Gentamycine active for?
Drug distributed with morphine for abuse?
Renal artery stenosis take verapamil but no benefit for htn which add?
Question for eplerenone?
Doxycycline not taken with?
Patient take t4 and has some symptoms? May be call doctor when fever something like this
Substituent for statin in intolerance?
Woman has hf and htn and incontinence need something fot hf? Captopril or another aceis cant
remember , furosemide, something bbs???
Should give for pneumonia in penicillin allergy?
Drug for woman cystitis?
Two questions about colistridium deficile which is wrong in severe cases? Stop antibiotic, isolate
patient, us…
[12:36 AM, 12/12/2022] Mustafa R. Wally: These all are Questions came in my paper 1 & 2 from July
2022 Recalls File:-
Q4.Another Q about amiodarone interaction: a. Inhibits metabolism of 3A4/ A5 substrates
Q6.Metformin dose reduction in which of the following:
a. Renal impairment
Q10.vaccines which is not taken in immunocompromised pts:
a. Yellow fever
Q12.DOC in ttt of hyperlipidaemia for a pt who CANNOT tolerate statins:
a. Cholestyramine
b. Colstipol
c. Ezetemib
Q18.Drug A CBZ 20mg/ml. Required dose 150 mg twice a day.
Drug B Valpoate 200mg/5ml. Required dose 250mg twice a day.
Calculate volume of Drug A and B for 4 weeks supply.
Answer: 420ml Drug A and 350 ml Drug B.
Q19. Least to cause hypokalemia: a.Salbutamol
b.Insulin
c.digoxin
d.Prednisolone
Q21.Nitroglycerin is taken sublinguall…
[12:36 AM, 12/12/2022] Mustafa R. Wally: Then vaccine which are not conjugated
And contraindicated for hiv vaccine I choose live vaccine
Clozapine monitering
Aspirin and acei
Which is not side effect of blocker b
Zolligen syndrome?
Paroxetin least side effect
Glaucoma medicine contraindicated ?
Pencillin resistance 3 questions
Clindamycin is not covering which one?
Shortest acting benzodiape
Smoking inducer which cytochrome
Conc depending killing?antibiotics
Statin memory loss
Digioxin toxicity in respect to potassium
Hypothyroidism which two drugs
Lithium and ammidrone
Acute gout
Treatment
Dose
Polyethylene glycol
Concentrate on vaccine
[12:36 AM, 12/12/2022] Mustafa R. Wally: Structures : celebrex and amphetamine , niacin ,
Some quest about keto acidosis, the active metabolite and receptors and asthma , diabetes
Acetzolamide and spironlacton many questions side effects and use
Same as the last session 2d6 and 1a2
Q 165
Enzyme receptor
Uric crystals
Tricyclic one question
Also there is a question .. Na meta bisulfite .. is not SAA
Calcitriol is Vit D analog used for Hypothy+2ry Hyperthyroidism
Calcitonin used in Hyperthyroidism
Then vaccine which are not conjugated
And contraindicated for hiv vaccine I choose live vaccine
Clozapine monitering
Aspirin and acei
Which is not side effect of blocker b
Zolligen syndrome?
Paroxetin least side effect
Glaucoma medicine contraindicated ?
Pencillin resistance 3 questi…
[12:36 AM, 12/12/2022] Mustafa R. Wally: Calculation:
1-Mmol of Li ( 8.13mmol)
2- Same Q 2 time in paper chlorohexidine ( 8.9ml )
3-0.16---- 0.04 mg calculation 11/2
4- 1.5ppm to prod 6000000ml ( ans : 30ml)
5- Dose ( 100) cp( 2.5) Vd find ( 40L )
6- Digoxin 36 hr find Css 6 days
7-Co ( 200) find con after 24 hr ( ans: 12.503)
8-300 mg Feso4 ( Ans : 60mg)
9- weight ( sensitivity 5 , error 5 ans : 100mg )
10-unioized/ ionized : 100:1
Another Q to PH but easy
11- Elimination 0.173 Find left after 16 hr ( ans ; 64hr )
12-Cpr ch 5 Q ( answr: 936mg )
[12:36 AM, 12/12/2022] Mustafa R. Wally: Today recalls
Ttt of pneoumccocal Jevorici: sulphamethoprim or Metronidazole
Interaction :
X- dipine _ grape fruit Or x- dipine _ statin
Which cause hyponatrimia
amphotricin or CBZ or paroxetine or fludrocortisone
- Tumor lysis syndrome : hyper or hypokalemia
[12:36 AM, 12/12/2022] Mustafa R. Wally: Lefunomide 1 question
Regarding dose and side effect
Organophosphate poison
Penicillin with longest duration of action
Nicotinic acid
Warfarin toxicity
Hcl secreted by with cell
Read haloperidol
Digitalis warfarin many question about them
Penicillin resistance to Penicillinase, acid resistance
Read about uti drug
TCS side effect
Drug not used in heat failure
Least side effect of beta blocker
Tradiv dyskancya
Opoid agonist and antagonist which are used in combination to withdrawal opoid dependence
These are from Australia 7 th Nov exam
I will keep on posting when I rember
Focus on Digitalis warfarin caliromathcyn amino glucoside side effect and toxicology surfacely
Don't go deep
Couple of questions from vaccine read detail about conjugated , and live vaccine
Anaphylaxis which ig
Which vit is toxic to pregnant lady
Mild symptoms on children under 12 dehydration
Which diuretic acts on which part of gf
Drug altering thyroid functin
Have knowledge about lice
Simple question about it
Simple question about psorisis
Not adverse effect of beta blocker
Lithium and amidoron
2 questin about it
What happen in psorosis
Colchicine dose for acute gut
Patient has diclofenac 7 day before for sport injury then doctor prescription ibuprofen what would
you do
Dispense it
Replace it
Ask to use 4 hrs after diclofenace
Dose of colchine in gout
Phenytoin and sartans met. Enzyme