Figure 2: Structures of different bioactive compounds from H.
rosa-sinensis : Quercetin, quercetin-3-diglucoside, ß-sitosterol, cyanidin-3,5-diglucoside [22], cyanidin-
3-sophoroside [25,26], and luteolin-8-C-glucoside [52].
Table 1: List of pharmacological effects of Hibiscus rosa sinensis
Pharmacological Part used Extract/fraction Dose tested/route of Animals/cell line culture Literatur
activity administration e cited
Anti-bacterial Leaves Methanolic 80 µg/ml S. aureus, E. aerogenes [27]
Aqueous 40 mg/ml B. subtilis, E. coli, S. aureus [28]
Flowers Hexane B. subtilis, E.coli [29]
Methanolic 500 mg, 1 mg /ml E. col, S. aureus, S.pyogenes [30,33]
Aqueous B. subtillis, E. coli [31]
Ethanolic Salmonella sp., P. aeruginosa [31]
Roots Ethyl alcohol 7.5 µg/ml S. aureus, E.coli , B. subtilis [32]
Anti-fungal Leaves Methanolic 80 µg/ml Aspergillus niger, Candida albicans [27]
C. glabreta, A. flavus, C. albicans
100 mg/ml [34]
Ethyl alcohol 10 µg/ml Candida parapsilosis [32]
Flower
50% ethanol Aspergillus terreus, Aspergillus [35]
oryzae
Root Ethyl alcohol 7.5 µg/ml Candida parapsilosis [32]
Anti-oxidant Leaves Aqueous DPPH and hydrogen peroxide [40, 41]
radicals
70% ethanol 500 µg/ml superoxide hydrogen peroxide, [42]
nitric oxide radicals
J Ayu Herb Med ǀ Vol 4 Issue 3 ǀ July- September 2018
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