Govt Villupuram medical college-Drug Formulary

Drug Dosage
NSAIDS
Paracetamol 10-15mg/kg/dose-q 4-6 hr
Ibuprofen 20-30mg/kg/day q6-8 hr
Antihistamines
Chlorphenirami 0.35mg/kg/day/ q4-6 hr
ne maleate 2-6 yrs-1mg
6-12 yrs-2mg
>12yrs-4mg q 4-6 hrs
Cetrizine 0.2mg/kg/day
Antiemetics
Domiperidone th
0.3mg/kg/dose/8 hrly
Ondansetron Oral dose
<4yrs-2mg q 4hr
4-11 yrs-4mg q hr
Antimicrobials
Amikacin 15-25 mg/kg/24hr divided q8-12h IV or IM
Ampicillin 100-200mg/kg/24hr divided q6h IV or IM
MENINGITIS - 200-400 mg/kg/24hr divided q4-6h IV or IM
Cap.Amoxicillin 20-50 mg/kg/24hr divided q8-12h PO.
Higher dose of 80-90 mg/kg 24hr PO for otitis media
Amoxicillin 20-45mg/kg/day q8-12h PO.
clavunate Higher dose: 80-90mg/kg/24hr PO for otitis media
Azithromycin Children:10mg/kg PO on day1(max dose: 500mg) followed by 5mg/kg
POq24h for 4 days
Group A streptococcus pharyngitis: 12 mg/kg/24hrPO (maxdose: 500mg) for
5 days
Cap.Cephalexin 25-50mg/kg/D-PO q 8hr
Cefixime 8 m g / k g /day oral once or twice a day.
For enteric fever 20 mg/kg/day q 12 hr or 24 hr.
Cefotaxim 100-150 mg/kg/ day q 6-8 hr. For
MENINGITIS - 200 mg/kg/day q 6 hi.
Ceftriaxone 50-75 mg/kg/ day IV g 12-24 hr. For
MENINGITIS - 100 mg/kg/ day q 12 hr (maximum dose 4gm).
C.Bactum 40-80mg/kg/day
Ciprofloxacin 20-40mg/kg/day PO
10-20mg/kg/day iv

Norfloxacin 10-15mg/kg/day
Doxycycline 2 - 5 m g / k g / day q 12 hr oral.
Piperacillin- 300-400mg/kg/24hr divided q6-8h IV or IM
tazobactam
Meropenem 60mg/kg/24 hr divided q8h IV
MENINGITIS - 120mg/kg/24hr (maxdose:6 g/24hr) q8h IV
Vancomycin 45-60 mg/kg/24hr divided q8-12h IV;
Clindamycin 20-30 mg/kg/ day q 6-8 hr oral, 20-40 mg/kg/day q6-8 hr IV.
Linezolid 10mg/kgq12h IV or PO
Clarithromycin 15 mg/kg/day q 12 hr oral.

Cloxacillin 50-100 mg/kg/day IV or oral (1 hr before or 2 hr after food) for

staphylococcal infection.
200 mg/kg/ day q 4hr for meningitis (maximum dose 4gm/day).
Tab.Erythromyci 30-50mg/kg/D-PO q6-8hr
n
Syp/Tab.Cotrim 5-8 mg/kg of TMP or 25-50 mg/kg of SMZ/ day q 12 hr oral or IV.
oxazole 10 mg/kg/ day q 12 hr of TMP for typhoid fever and
20 mg/kg/day q 6-8 hr of TMP for Pneumocystis carinii infection.
Single dose 1-3 mg/kg/day of TMP for UTI prophylaxis.
Gentamicin 5-7.5mg/kg/24hr IV once daily
Metronidazole 30mg/kg/24hr dividedq6-8h PO or IV
Tab.Penicillin V children <5 yrs 125 mg/ dose,
6-12 yrs 250 mg/ dose administered q 6 hr 30 minutes before or 2 hr after
food.
For rheumatic prophylaxis 250 mg orally twice daily.
Benzathine 0.6 mega units MI 3 weekly below 6 years of age(27kg) and above 27 kgs-1.2
penicillin G mega units IM every 3 weeks after
6 years of age for secondary prophylaxis against rheumatic fever.
Acyclovir Varicella -80 mg/kg/d q 6hr for 5days,
Herpes simplex 200 mg q4 hr for 5 days

Albendazole 200 mg single dose for children between 1and 2 years, 400 mg single dose for
children above 2 years
For giardiasis 400mg daily for 5 days
For neurocysticercosis give 15 mg/kg/d in 2div doses for 7 days along with
corticosteroids for5 days to reduce cerebral edema. Albendazole is started on
day 3of steroid therapy.
Oseltamavir <15 kg 30 mg q 12 hr,
15-23 kg 45 mg q 12hr,
23-40kg60mgq12hrs,
>40kg75mgq12hroralfor 5days;
Prophylaxis: same dose as above but once daily for 7-10 days
Antimalarials
Artesunate Severe falciparum malaria: 2.4 mg /kg/dose VI or IM at 0, 12, 24 hours,
followed by OD for 7days. Shift to oral therapy once the child is able to
swallow.
Tab. 10mg of base/kg stat, followed by 5mg/kg after 6 hrs and then once a day for
Chloroquine 2 days (total 25 mg)
phosphate
Electrolyte Supplements
ORS 10ml/kg for every loose stools
(packet to be diluted in one litre of boiled, cooled water-used in 24 hours)
Potassium 1-2 mEq/kg/day q 8 hr oral
chloride potasol 15 ml provides 20 mEq (1.5 gKCI) of K* and potassium chloride
injection 15% 10 ml ampoules provide 2 mEq of *K per ml
Bronchodilators
Salbutamol 0.1-0.4mg/dose/8th hrly
Salbutamol >6 months-0.5ml in 2-4 ml NS
nebulisation <6 months-0.25ml in 2-4 ml NS
Cardiac glycoside
Digoxin Digitalization (1/2 initially, followed by ¼ q 12h*2)
25-40microgram/kg PO
Maintenance:5-10 microgram/kg/day, divided q 12h
Antihypertensive drugs
Furosemide IV:0.5-2 mg/kg/dose
PO: 1-4 mg/kg/day, divided bd-qid max: 6mg/kg/day
Spironolactone PO:1-3mg/kg/day, divided bid or tid
Enalapril PO:0.08-0.5mg/kg/day, divided q 12-24 hr
Metoprolol PO:0.2mg/kg/day divided bid, increase gradually to wk intervals) to maximum
dose of 1-2mg/kg/day
Verapamil 4-8 mg/kg/day q 8 hr oral, 0.1-0.3 mg/kg VI over 2 min under continuous ECG
and BP monitoring.
Propanolol For arrhythmia/ cyanotic spells: 2-6 mg/kg/day q 6-8 hr oral.
Nifedipine 0.2-0.5 mg/kg/day qd-bid , maximum:3mg/kg /day
Anticonvulsants
Phenytoin 5-8 mg/kg/day q 8-12 hr or single dose oral.
Phenobarbitone 3-5 mg/kg/day q 12 hr or single dose at night oral or IV.
Sodium Initial 10-15 mg/kg/ day q 8-12 hr oral, can increase up to maximum of 60 mg
valproate / kg/ day
Levetiracetam S t a r t a t 10 m g / k g / d a y q 12 h r , i n c r e a s e b y 10mg/kg upto 2 week
Maximum 60mg /kg/day.
Clobazam 0.1 m g / k g / day initial dose. Usual maintenance dose 0.3-1 mg/kg/ day at
bedtime or q 12 hr. 1mg /kg/day q 12 hr for 2-3 days for prophylaxis against
febrile seizures.
Clonazepam 0.01-0.03 m g / k g / day q 8-12 hr oral. Increase every 3days by 0.25-0.5 mg
till a maximum dose of 0.2 mg / kg/day is reached.
Magnesium 2-3mEq/kg/dayfor PEM. Magnesium sulfate 50% solution provides 4 mEq/ml
sulfate of elemental magnesium. Give 0.5-1.0 ml/kg/ day q 6 hr IM.
Status asthmaticus
Hormone tablets
Levo – thyroxine infancy 6-8 pg/kg/day;
Children: 1-3 yrs, 5-6 ug/kg/ day;
5-10 yrs, 4-5 pg/kg/ day;
>10 yrs, 2-3u g/kg/ day,in asingle dose oral on empty stomach in the
morning.
GIT Drugs
Lactulose 1-2 ml/kg/day g 6 hr orally in children with hepatic coma and constipation.
UDCA 10-15 m g / k g / day g 8 hr
Ranitidine 2-4 mg/kg per day q 12 hr oral
Omeprazole 1 mg/kg/day in a single or 2 div doses
Mannitol (20%) 5ml/kg initially, thereafter 2 ml/kg every 6hr for 2days or 0.5-3.0 g/kg/dose
q8hr.
Vitamin and Mineral supplements
Tab. Zinc 20mg/day for >6 months
10mg/day for <6 months
Iron For prophylaxis, Elemental iron is 1 -2mg/kg/dayg12hr oral
for treatment 3 mg/kg/day q 12 hr oral in
between meals.
Folic acid Megaloblastic anemia: 0.5-1mg/day for 4 weeks followed by usual
maintenance (up to 200 pg/day)
Hemolytic anemia: 1 mg daily.
Vitamin A For prophylaxis
1. Children at risk and during measles: 1,00,000 iu <12 months age, 2,00,000
iu >12 months age PO every 6 months.
2. Prevention of BPD in neonates: 5000 iu intramuscular 3 days in a week for
28days
3.Improvement of growth in children with HIV, malaria, or diarrheal disease:
Infants <1 yr: 100,000 iu/ day for 2doses, then 100,000 iu at 4 and 8 months
Children >1 yr: 200,000i u / day for 2doses then 200,000 iu at 4 and 8 months
Vitamin A deficiency with xerophthalmia
<6 months: 50,000 iu PO
6-12 months: 100,000 iu >1 year: 200,000 iu PO
Vitamin D Deficiency:60,000 iu daily for 10 days or weekly for 10 weeks oral.
Pryidoxine 0.3-3 mg/kg/day oral,IM or IV
Pyridoxine- dependent seizures: 100 mg over 1 min IV (maximum dose 400
mg) with EEG monitoring followed by maintenance dose of 50-100 mg/ d.
Vitamin B12 Therapeutic dose 250 to 1000 ug IM on alternateday for 1to 2 weeks, then
weekly until bloodcount
is normal. Maintenance dose 1000 kg 2-4 monthly.