In the IMAT (International Medical Admissions Test), the topic "The Chemistry of Living
Things" is part of the General Chemistry and Biology sections. Below is a breakdown of
topics, subtopics, and specific concepts/articles you should study for IMAT 2025 under The
Chemistry of Living Things.
🧪 Topic: The Chemistry of Living Things
This typically overlaps between Chemistry and Biology, especially Biochemistry.
📌 1. Biochemical Molecules (Macromolecules)
Subtopics:
Carbohydrates
o Monosaccharides (glucose, fructose, galactose)
o Disaccharides (sucrose, lactose, maltose)
o Polysaccharides (starch, glycogen, cellulose)
o Glycosidic bonds
Lipids
o Fatty acids (saturated vs unsaturated)
o Triglycerides
o Phospholipids
o Steroids (e.g., cholesterol)
o Functions (energy storage, insulation, cell membrane)
Proteins
o Amino acids and peptide bonds
o Primary, secondary, tertiary, quaternary structures
o Enzymes (structure, function, specificity, denaturation)
Nucleic Acids
o DNA and RNA structure
o Nucleotides (sugar, phosphate, nitrogenous bases)
o Base pairing rules (A-T, C-G for DNA; A-U for RNA)
o DNA replication, transcription, translation basics
📌 2. Water and Its Importance
Subtopics:
Polarity of water
Hydrogen bonding
Cohesion and adhesion
High specific heat
Solvent properties
Role in biological systems
📌 3. Enzymes and Metabolism
Subtopics:
Role of enzymes as biological catalysts
Substrate specificity
Enzyme-substrate complex
Active site, induced fit model
Factors affecting enzyme activity (pH, temperature, concentration)
Inhibitors: competitive vs non-competitive
📌 4. Energy and Biochemical Reactions
Subtopics:
Endergonic vs exergonic reactions
Activation energy
Role of ATP
Redox reactions in metabolism
Cellular respiration (glycolysis, Krebs cycle, oxidative phosphorylation – basic overview)
📌 5. pH and Buffers
Subtopics:
Acids and bases in biological systems
pH scale
Buffers and their role in maintaining homeostasis (e.g., bicarbonate buffer system in
blood)
📚 Recommended Articles/Concepts to Review:
Though the IMAT doesn't cite specific research papers, here are standard textbook sections and
concepts that align with the exam content:
Campbell Biology (Chapters 2–5): Chemistry of life, water, carbon, macromolecules
Biochemistry basics – Khan Academy or YouTube lectures
A-level/IB Chemistry and Biology curriculum – especially biomolecules
MIT OpenCourseWare – Intro to Biology/Organic Chemistry (for deeper review)
🧠 Tips for IMAT 2025 Preparation:
Focus on functional groups in biomolecules (e.g., amino, carboxyl, hydroxyl).
Understand structure-function relationships (e.g., how protein folding affects function).
Be clear on enzymatic mechanisms and metabolic energy flow.
Practice applying knowledge, not just memorizing (IMAT favors reasoning-based
MCQs).
Would you like a PDF summary or flashcards of these topics?