Wesley Wade N.
Quiño General Biology 2
Jhoris Aian S. Gomez Mr. Kenneth A. Lamba
Grade 12 - St. Luke
Informative Write-Up Report: A Guide to Global COVID-19 Vaccine Efforts
Since the beginning of the pandemic, the worldwide has put the effort to create and disseminate
COVID-19 vaccinations that people have talked a lot about public health. In the biggest effort in
working together to stop the spread of the virus, governments such as the U.S and China, many
pharmaceutical companies, and both academic and research institutions have been working non-stop
to create safe and effective vaccines. To shed light on the difficulties, achievements, and potential
futures of global vaccination campaigns, this report attempts to present a thorough analysis of the
global COVID-19 vaccine efforts.
Vaccines have traditionally been produced using inactive or weakened virus components, referred to
as antigens. These antigens trigger the body's defensive white blood cells within the immune system
to generate antibodies that are capable of attaching to the virus and deactivating it. The leading
COVID-19 vaccines have been mostly approved for the use that have been developed by firms and
research groups in China, Russia, and the United States. The vaccine doses needed for a person to
be vaccinated is at least once or twice to be effective in preventing this serious illness.
As seen in Figure 1, the data has shown that vaccines have an efficacy rate of more than 50% to as
its minimum and while the maximum efficacy rate to some of the vaccines have an increased percent
rate of more than 90% which has been proven its effectiveness against the infectious disease.
According to the U.S, some of the vaccine companies have been approved because of their
prominent vaccines that will be used for emergency to be distributed in the country.
Figure 1. Efficacy Rate of Leading COVID-19 Vaccines
Vaccine development is a sequential process that takes eight to fifteen years on average from the lab
to the point where health care providers can administer the vaccine. For example, if the vaccine
production process started in the 2000s, the vaccines would be administered in around in the 2010s
that have undergone research for 2-4 years, preclinical preparation for 2 years, clinical trials up to 5
years, regulatory approvals in 1 year, manufacturing in 2 years and distribution for at least 6 months
from over a decade or more.
Figure 2. Gantt Chart for a Normal Vaccine
Production Process
However, as for the COVID-19 vaccine production process would only take up to 12-18 months
representing a groundbreaking accomplishment in the history of vaccine development.
The development stages has sped up the process simultaneously by looking to new vaccine
technologies resulted to finish up to 6 months, except for the vaccines’ distribution taking up to a
month. Thanks to the U.S. Operation Warp Speed timeline that hinged on overlapping stages of
development; mass production started for strong candidates even while clinical trials were ongoing
which found another way for researchers in speeding up the process by focusing on new vaccine
approaches.
Figure 3. Gantt Chart for a COVID-19 Vaccine
Production Process
The findings of the article has demonstrated that the vaccine’s development and distribution process
made a significant progress which showcases the cooperative efforts of scientists, researchers,
pharmaceutical companies, and academic and research institutions worldwide in overcoming the
obstacles during the pandemic.
As global efforts continues to distribute COVID-19 vaccines around the world, it is important for us to
working together in responding this health crisis against the COVID-19 pandemic. Eventually, the
success of creating the vaccines will contribute to fight against COVID-19 shows the dedication of
protecting the health and well-being for people around the world.
Feedback:
Person 1: “This report to me informs me about the time and manufacturing in developing a vaccine.
The report provides information to me about the vaccine timeline through statistical figures and
charts. It is clearly well thought out from the article, and would very much recommend it to someone
who is interested in medicine.”
Person 2: "All sums up the article very well, informative and good."
Person 3: "It has pointed out all of the key points that can be found in the article about the efforts
during Covid-19. It has done a amazing job in reporting the overall summary of the report."
