PLANTS

Serial
Drug Name Source Plant Type of Drug
Number
Analgesic, anti-
1 Aspirin Willow bark (Salix spp.)
inflammatory
Opium poppy (Papaver
2 Morphine Analgesic, narcotic
somniferum)
Cinchona tree (Cinchona
3 Quinine Antimalarial
spp.)
Foxglove (Digitalis
4 Digoxin Cardiac glycoside
purpurea)
Deadly nightshade
5 Atropine Anticholinergic
(Atropa belladonna)
Pacific yew tree (Taxus Anticancer
6 Taxol
brevifolia) (chemotherapeutic)
7 Ephedrine Ephedra species Decongestant, stimulant
Madagascar periwinkle Anticancer
8 Vinblastine
(Catharanthus roseus) (chemotherapeutic)
Pacific yew tree (Taxus Anticancer
9 Paclitaxel
brevifolia) (chemotherapeutic)
10 Salicylic acid Willow bark (Salix spp.) Keratolytic agent
Indian snakeroot Antihypertensive,
11 Reserpine
(Rauwolfia serpentina) antipsychotic
Coca plant Local anesthetic,
12 Cocaine
(Erythroxylum coca) stimulant
Sweet wormwood
13 Artemisinin Antimalarial
(Artemisia annua)
Analgesic, anti-
14 Cannabidiol (CBD) Cannabis sativa
inflammatory
Jimsonweed (Datura
15 Scopolamine Anticholinergic
stramonium)
Turmeric (Curcuma Anti-inflammatory,
16 Curcumin
longa) antioxidant
Chili peppers (Capsicum
17 Capsaicin Analgesic, topical irritant
spp.)
Happy tree
Anticancer
18 Camptothecin (Camptotheca
(chemotherapeutic)
acuminata)
Snowdrop (Galanthus Acetylcholinesterase
19 Galantamine
spp.) inhibitor
Foxglove (Digitalis
20 Digitalis Cardiotonic
purpurea)
Autumn crocus Anti-inflammatory, gout
21 Colchicine
(Colchicum autumnale) treatment
22 Codeine Opium poppy (Papaver Analgesic, antitussive
Serial
Drug Name Source Plant Type of Drug
Number
somniferum)
Jaborandi (Pilocarpus
23 Pilocarpine Ophthalmic agent, miotic
spp.)
Yohimbe tree
24 Yohimbine Aphrodisiac
(Pausinystalia johimbe)
Wild yam (Dioscorea Precursor for steroid
25 Diosgenin
spp.) synthesis
Peppermint (Mentha Cooling sensation,
26 Menthol
spp.) topical analgesic
Ginkgo tree (Ginkgo
27 Ginkgo biloba extract Cognitive enhancer
biloba)
Senna (Senna
28 Sennosides Laxative
alexandrina)
Goldenseal (Hydrastis
29 Berberine Antimicrobial
canadensis)
Pacific yew tree (Taxus Anticancer
30 Paclitaxel
brevifolia) (chemotherapeutic)
Indian snakeroot Antihypertensive,
31 Rauwolfia alkaloids
(Rauwolfia serpentina) antipsychotic
Madagascar periwinkle Anticancer
32 Vincristine
(Catharanthus roseus) (chemotherapeutic)
33 Betulinic acid Birch tree (Betula spp.) Antiretroviral, anticancer
Cocoa (Theobroma
34 Theobromine Stimulant
cacao)
Antiemetic, appetite
35 Dronabinol Cannabis sativa
stimulant
36 Ephedrine Ephedra species Decongestant, stimulant
Tetrahydrocannabinol
37 Cannabis sativa Psychoactive, analgesic
(THC)
Thyme (Thymus
38 Thymol Antiseptic
vulgaris)
Mayapple (Podophyllum
39 Podophyllotoxin Antiviral, anticancer
peltatum)
Cotton (Gossypium
40 Gossypol Male contraceptive
spp.)
Bearberry
41 Arbutin (Arctostaphylos uva- Skin lightening agent
ursi)
42 Papain Papaya (Carica papaya) Digestive enzyme
Chili peppers (Capsicum
43 Capsaicin Analgesic, topical irritant
spp.)
Anti-inflammatory,
44 Tetrandrine Stephania tetrandra
antifibrotic
45 Berberine Goldenseal (Hydrastis Antimicrobial
Serial
Drug Name Source Plant Type of Drug
Number
canadensis)
Red grapes (Vitis Antioxidant, anti-
46 Resveratrol
vinifera) inflammatory
Analgesic, anti-
47 Salicin Willow bark (Salix spp.)
inflammatory
Bergamot orange (Citrus Aromatherapy,
48 Bergamot oil
bergamia) antidepressant
Hormone replacement
49 Estradiol Soy (Glycine max)
therapy
Licorice (Glycyrrhiza Anti-inflammatory,
50 Glycyrrhizin
glabra) expectorant
Antioxidant,
51 Hesperidin Citrus fruits
cardiovascular health
Tomatoes (Solanum Antioxidant, prostate
52 Lycopene
lycopersicum) health
53 Melatonin Various plants Sleep aid
Broccoli (Brassica
54 Sulforaphane Antioxidant, anticancer
oleracea)
55 Theophylline Tea (Camellia sinensis) Bronchodilator
Apple peel (Malus Anti-inflammatory,
56 Ursolic acid
domestica) antioxidant

Serial
Drug Name Source Plant Type of Drug
Number
Sugar beets (Beta Methyl donor,
57 Betaine
vulgaris) osmoprotectant
58 Cathinone Khat (Catha edulis) Stimulant
Venotonic, anti-
59 Diosmin Citrus fruits
inflammatory
Indian coleus (Coleus Weight loss,
60 Forskolin
forskohlii) cardiovascular health
Adaptogen, cognitive
61 Ginsenosides Ginseng (Panax ginseng)
enhancer
Ipecacuanha (Cephaelis
62 Ipecac Emetic
ipecacuanha)
Kava (Piper
63 Kavalactones Anxiolytic, sedative
methysticum)
Indian tobacco (Lobelia
64 Lobeline Respiratory stimulant
inflata)
Fly agaric (Amanita
65 Muscimol Psychoactive
muscaria)
66 Naringin Citrus fruits Flavonoid, antioxidant
Serial
Drug Name Source Plant Type of Drug
Number
67 Paeoniflorin Peony (Paeonia lactiflora) Anti-inflammatory
68 Rutaecarpine Evodia rutaecarpa Antiplatelet
Lithospermum Anti-inflammatory,
69 Shikonin
erythrorhizon wound healing
70 Tetrahydropalmatine Corydalis yanhusuo Analgesic
Belladonna (Atropa
71 Tropane alkaloids Anticholinergic, analgesic
belladonna)
Valerian (Valeriana
72 Valerenic acid Anxiolytic, sedative
officinalis)
Malabar nut (Adhatoda Expectorant,
73 Vasicine
vasica) bronchodilator
Passionflower (Passiflora
74 Vitexin Anxiolytic, sedative
incarnata)
75 Ajmalicine Rauvolfia serpentina Antihypertensive
Anti-inflammatory,
76 Alpha-pinene Pine (Pinus spp.)
bronchodilator
Anise (Pimpinella Flavoring agent, digestive
77 Anethole
anisum) aid
Oregon grape (Mahonia
78 Berberastine Antimicrobial
aquifolium)
Anti-inflammatory,
79 Cannabigerol (CBG) Cannabis sativa
neuroprotective
Chili peppers (Capsicum
80 Capsaicinoid Analgesic, topical irritant
spp.)
Oregano (Origanum
81 Carvacrol Antimicrobial, antioxidant
vulgare)
Sweet clover (Melilotus
82 Coumarin Anticoagulant
spp.)
Turmeric (Curcuma Anti-inflammatory,
83 Curcuminoids
longa) antioxidant
84 Daidzein Soy (Glycine max) Phytoestrogen
85 Ellagic acid Berries, nuts Antioxidant, anticancer
Cloves (Syzygium
86 Eugenol Analgesic, antiseptic
aromaticum)
Antioxidant, anti-
87 Flavonoids Various plants
inflammatory
88 Fucoidan Brown algae Anticoagulant, anticancer
89 Genistein Soy (Glycine max) Phytoestrogen, anticancer
Licorice (Glycyrrhiza Anti-inflammatory,
90 Glycyrrhetinic acid
glabra) antiviral
Syrian rue (Peganum Hallucinogen,
91 Harmine
harmala) antidepressant
Antioxidant, anti-
92 Kaempferol Various plants
inflammatory
Serial
Drug Name Source Plant Type of Drug
Number
Antioxidant, anti-
93 Luteolin Celery, parsley
inflammatory
Antioxidant, anti-
94 Myricetin Berries, nuts
inflammatory
Antioxidant,
95 Nobiletin Citrus fruits
neuroprotective
Antioxidant,
96 Oleuropein Olive (Olea europaea)
cardiovascular health
Indian snakeroot
97 Picrotoxin Convulsant
(Anamirta cocculus)
Black pepper (Piper
98 Piperine Bioavailability enhancer
nigrum)
Antioxidant, anti-
99 Quercetin Various plants
inflammatory
Buckwheat (Fagopyrum
100 Rutin Venotonic, antioxidant
esculentum)

MICROBES
Serial
Drug Name Source Microbe Type of Drug
Number
1 Penicillin Penicillium spp. Antibiotic, bactericidal
2 Streptomycin Streptomyces griseus Antibiotic, bactericidal
Saccharopolyspora
3 Erythromycin Antibiotic, bacteriostatic
erythraea
Amycolatopsis
4 Vancomycin Antibiotic, bactericidal
orientalis
5 Tetracycline Streptomyces spp. Antibiotic, bacteriostatic
Antifungal, polyene
6 Amphotericin B Streptomyces nodosus
antibiotic
Tolypocladium
7 Cyclosporine Immunosuppressant
inflatum
Serial
Drug Name Source Microbe Type of Drug
Number
Streptomyces Immunosuppressant,
8 Rapamycin (Sirolimus)
hygroscopicus anticancer
Streptomyces
9 Clindamycin Antibiotic, bacteriostatic
lincolnensis
10 Azithromycin Streptomyces spp. Antibiotic, bacteriostatic
11 Cephalosporins Acremonium spp. Antibiotic, bactericidal
12 Bacitracin Bacillus subtilis Antibiotic, bactericidal
Micromonospora
13 Gentamicin Antibiotic, bactericidal
purpurea
Streptomyces
14 Chloramphenicol Antibiotic, bacteriostatic
venezuelae
Amycolatopsis
15 Rifampin Antibiotic, bactericidal
rifamycinica
16 Isoniazid Streptomyces spp. Antitubercular
17 Streptokinase Streptococcus spp. Thrombolytic
Antifungal, polyene
18 Nystatin Streptomyces noursei
antibiotic
19 Neomycin Streptomyces fradiae Antibiotic, bactericidal
20 Polymyxin B Bacillus polymyxa Antibiotic, bactericidal
Penicillium
21 Griseofulvin Antifungal
griseofulvum
22 Actinomycin D Streptomyces spp. Antineoplastic
23 Ciprofloxacin Streptomyces spp. Antibiotic, bactericidal
24 Epothilones Sorangium cellulosum Anticancer
25 Paclitaxel (Taxol) Taxomyces andreanae Anticancer
26 Lovastatin Aspergillus terreus Antihyperlipidemic
Streptomyces
27 Ivermectin Antiparasitic
avermitilis
Streptomyces
28 Doxorubicin Anticancer
peucetius
Streptomyces
29 Bleomycin Anticancer
verticillus
Streptomyces
30 Amikacin Antibiotic, bactericidal
kanamyceticus
31 Streptavidin Streptomyces avidinii Biotechnological tool
Streptomyces
32 Tunicamycin Antifungal, antitumor
lysosuperificus
Paenibacillus
33 Colistin Antibiotic, bactericidal
polymyxa
34 Lactobionic acid Lactobacillus spp. Hepatoprotective
35 Tylosin Streptomyces fradiae Antibiotic, bacteriostatic
Streptomyces
36 Mitomycin C Anticancer
caespitosus
37 Mupirocin Pseudomonas Antibiotic, bactericidal
Serial
Drug Name Source Microbe Type of Drug
Number
fluorescens
Streptomyces Immunosuppressant,
38 Rapamycin (Sirolimus)
hygroscopicus anticancer
39 Streptokinase Streptococcus spp. Thrombolytic
40 Nisin Lactococcus lactis Antibacterial peptide
Streptomyces Immunosuppressant,
41 Everolimus (RAD001)
hygroscopicus anticancer
42 Linezolid Streptomyces spp. Antibiotic, bacteriostatic
43 Nalidixic acid Streptomyces spp. Antibiotic, bactericidal
Pseudoplectania
44 Plectasin Antibacterial peptide
nigrella
45 Tedizolid Streptomyces spp. Antibiotic, bacteriostatic
46 Telavancin Streptomyces spp. Antibiotic, bactericidal
Actinoplanes
47 Teicoplanin Antibiotic, bactericidal
teichomyceticus
Streptomyces
48 Daptomycin Antibiotic, bactericidal
roseosporus
49 Capreomycin Streptomyces spp. Antitubercular
Dactylosporangium
50 Fidaxomicin Antibiotic, bactericidal
aurantiacum
51 Fosfomycin Streptomyces fradiae Antibiotic, bactericidal
52 Tigecycline Streptomyces spp. Antibiotic, bacteriostatic
Bacillus Calmette-
53 Mycobacterium bovis Vaccine, tuberculosis
Guérin
54 Nocardamine Nocardia spp. Antifungal
Micromonospora
55 Micafungin Antifungal, echinocandin
echinospora
56 Caspofungin Aspergillus fumigatus Antifungal, echinocandin
57 Doripenem Streptomyces cattleya Antibiotic, bactericidal
58 Moxifloxacin Streptomyces spp. Antibiotic, bactericidal
59 Delamanid Streptomyces spp. Antitubercular
60 Bedaquiline Streptomyces spp. Antitubercular
61 Nisin Lactococcus lactis Antibacterial peptide
Streptomyces
62 Nivolumab Immunotherapy, anticancer
hygroscopicus
63 Pembrolizumab Streptomyces spp. Immunotherapy, anticancer
Streptomyces Monoclonal antibody,
64 Trastuzumab
hygroscopicus anticancer
Streptomyces Monoclonal antibody,
65 Rituximab
hygroscopicus anticancer
Streptomyces Monoclonal antibody, anti-
66 Adalimumab
hygroscopicus inflammatory
67 Infliximab Streptomyces Monoclonal antibody, anti-
Serial
Drug Name Source Microbe Type of Drug
Number
hygroscopicus inflammatory
Streptomyces Fusion protein, anti-
68 Etanercept
hygroscopicus inflammatory
Antifungal, polyene
69 Amphotericin B Streptomyces nodosus
antibiotic
70 Lactobionic acid Lactobacillus spp. Hepatoprotective
Recombinant human
71 Teriparatide Escherichia coli
protein, osteoporosis
Recombinant human
72 Somatropin Escherichia coli
protein, growth hormone
Recombinant human
73 Insulin Escherichia coli
protein, diabetes
Granulocyte colony-
Recombinant human
74 stimulating factor (G- Escherichia coli
protein, hematopoiesis
CSF)
Recombinant human
75 Interferon beta Escherichia coli
protein, antiviral
Recombinant human
76 Pegfilgrastim Escherichia coli
protein, hematopoiesis
Recombinant human
77 Epoetin alfa Escherichia coli
protein, erythropoiesis
Recombinant human
78 Filgrastim Escherichia coli
protein, hematopoiesis
Recombinant human
79 Dornase alfa Escherichia coli
protein, cystic fibrosis
Chromobacterium Anticancer, histone
80 Romidepsin
violaceum deacetylase inhibitor
81 L-asparaginase Escherichia coli Enzyme therapy, anticancer
Recombinant human
82 Aldesleukin Escherichia coli
protein, immunotherapy
Monoclonal antibody,
83 Palivizumab Escherichia coli
respiratory syncytial virus
Saccharomyces Fusion protein,
84 Abatacept
cerevisiae autoimmune diseases
Monoclonal antibody, anti-
85 Adalimumab Escherichia coli
inflammatory
Saccharomyces Fusion protein,
86 Belatacept
cerevisiae immunosuppressant
Monoclonal antibody, anti-
87 Infliximab Escherichia coli
inflammatory
Monoclonal antibody,
88 Omalizumab Escherichia coli
asthma
Monoclonal antibody,
89 Ustekinumab Escherichia coli
autoimmune diseases
Serial
Drug Name Source Microbe Type of Drug
Number
Monoclonal antibody,
90 Abciximab Escherichia coli
antithrombotic
Monoclonal antibody,
91 Natalizumab Escherichia coli
multiple sclerosis
Monoclonal antibody,
92 Rituximab Escherichia coli
anticancer
Monoclonal antibody,
93 Vedolizumab Escherichia coli
autoimmune diseases
Monoclonal antibody,
94 Bevacizumab Escherichia coli
anticancer
Monoclonal antibody,
95 Eculizumab Escherichia coli
complement inhibitor
Monoclonal antibody,
96 Tocilizumab Escherichia coli
autoimmune diseases
Monoclonal antibody,
97 Certolizumab pegol Escherichia coli
autoimmune diseases
Monoclonal antibody,
98 Golimumab Escherichia coli
autoimmune diseases
Monoclonal antibody,
99 Secukinumab Escherichia coli
autoimmune diseases
Monoclonal antibody,
100 Alemtuzumab Escherichia coli
anticancer

SYNTHETHIC SOURCES
Serial
Drug Name Synthetic Source Type of Drug
Number
Acetaminophen
1 Organic synthesis Analgesic, antipyretic
(Paracetamol)
Nonsteroidal anti-inflammatory
2 Ibuprofen Organic synthesis
drug (NSAID)
3 Metformin Organic synthesis Antidiabetic
4 Omeprazole Organic synthesis Proton-pump inhibitor
5 Simvastatin Organic synthesis Statin, antihyperlipidemic
6 Atenolol Organic synthesis Beta blocker
Selective serotonin reuptake
7 Citalopram Organic synthesis
inhibitor (SSRI)
8 Clopidogrel Organic synthesis Antiplatelet
Selective serotonin reuptake
9 Fluoxetine Organic synthesis
inhibitor (SSRI)
10 Gabapentin Organic synthesis Anticonvulsant, analgesic
11 Levofloxacin Organic synthesis Antibiotic, fluoroquinolone
12 Lisinopril Organic synthesis ACE inhibitor
13 Metoprolol Organic synthesis Beta blocker
Serial
Drug Name Synthetic Source Type of Drug
Number
14 Pregabalin Organic synthesis Anticonvulsant, analgesic
Selective serotonin reuptake
15 Sertraline Organic synthesis
inhibitor (SSRI)
16 Rosuvastatin Organic synthesis Statin, antihyperlipidemic
Selective serotonin reuptake
17 Escitalopram Organic synthesis
inhibitor (SSRI)
Serotonin-norepinephrine reuptake
18 Venlafaxine Organic synthesis
inhibitor
19 Alprazolam Organic synthesis Benzodiazepine, anxiolytic
20 Atorvastatin Organic synthesis Statin, antihyperlipidemic
Antidepressant, smoking cessation
21 Bupropion Organic synthesis
aid
Serotonin-norepinephrine reuptake
22 Duloxetine Organic synthesis
inhibitor
23 Esomeprazole Organic synthesis Proton-pump inhibitor
24 Fluconazole Organic synthesis Antifungal
Selective serotonin reuptake
25 Paroxetine Organic synthesis
inhibitor (SSRI)
26 Quetiapine Organic synthesis Atypical antipsychotic
27 Risperidone Organic synthesis Atypical antipsychotic
PDE5 inhibitor, erectile
28 Tadalafil Organic synthesis
dysfunction
29 Valsartan Organic synthesis Angiotensin II receptor antagonist
30 Zolpidem Organic synthesis Sedative-hypnotic
31 Aripiprazole Organic synthesis Atypical antipsychotic
32 Carvedilol Organic synthesis Beta blocker, alpha blocker
Serotonin-norepinephrine reuptake
33 Desvenlafaxine Organic synthesis
inhibitor
Recombinant Recombinant human protein,
34 Epoetin alfa
DNA technology erythropoiesis
Recombinant Recombinant human protein,
35 Filgrastim
DNA technology hematopoiesis
Recombinant Recombinant human insulin, long-
36 Insulin glargine
DNA technology acting
Recombinant Recombinant human protein,
37 Interferon alfa
DNA technology antiviral
Recombinant Recombinant human protein,
38 Pegfilgrastim
DNA technology hematopoiesis
Recombinant
39 Rituximab Monoclonal antibody, anticancer
DNA technology
Recombinant
40 Trastuzumab Monoclonal antibody, anticancer
DNA technology
Recombinant
41 Bevacizumab Monoclonal antibody, anticancer
DNA technology
Serial
Drug Name Synthetic Source Type of Drug
Number
Recombinant Monoclonal antibody, anti-
42 Adalimumab
DNA technology inflammatory
Recombinant
43 Etanercept Fusion protein, anti-inflammatory
DNA technology
Recombinant Monoclonal antibody, anti-
44 Infliximab
DNA technology inflammatory
Recombinant Fusion protein, autoimmune
45 Abatacept
DNA technology diseases
Recombinant Recombinant human protein,
46 Epoetin beta
DNA technology erythropoiesis
47 Glatiramer acetate Organic synthesis Multiple sclerosis treatment
Levothyroxine
48 Organic synthesis Thyroid hormone
sodium
49 Methotrexate Organic synthesis Antimetabolite, antifolate
Recombinant Monoclonal antibody, multiple
50 Natalizumab
DNA technology sclerosis
Recombinant Monoclonal antibody, respiratory
51 Palivizumab
DNA technology syncytial virus
Recombinant Recombinant human protein,
52 Peginterferon alfa
DNA technology antiviral
Recombinant Recombinant human protein,
53 Teriparatide
DNA technology osteoporosis
Recombinant Monoclonal antibody, autoimmune
54 Ustekinumab
DNA technology diseases
Recombinant Monoclonal antibody,
55 Abciximab
DNA technology antithrombotic
Recombinant Monoclonal antibody, autoimmune
56 Certolizumab pegol
DNA technology diseases
Recombinant Monoclonal antibody, complement
57 Eculizumab
DNA technology inhibitor
Recombinant Monoclonal antibody, autoimmune
58 Golimumab
DNA technology diseases
Recombinant Monoclonal antibody, multiple
59 Natalizumab
DNA technology sclerosis
Recombinant Monoclonal antibody, autoimmune
60 Secukinumab
DNA technology diseases
Recombinant Monoclonal antibody, autoimmune
61 Tocilizumab
DNA technology diseases
Recombinant Monoclonal antibody, autoimmune
62 Vedolizumab
DNA technology diseases
Recombinant
63 Alemtuzumab Monoclonal antibody, anticancer
DNA technology
Recombinant Fusion protein,
64 Belatacept
DNA technology immunosuppressant
Serial
Drug Name Synthetic Source Type of Drug
Number
Recombinant Recombinant human protein, cystic
65 Dornase alfa
DNA technology fibrosis
Anticancer, histone deacetylase
66 Romidepsin Organic synthesis
inhibitor
67 L-Asparaginase Organic synthesis Enzyme therapy, anticancer
Recombinant Recombinant human protein,
68 Aldesleukin
DNA technology immunotherapy
Recombinant Monoclonal antibody, respiratory
69 Palivizumab
DNA technology syncytial virus
Recombinant Fusion protein, autoimmune
70 Abatacept
DNA technology diseases
Recombinant Monoclonal antibody, anti-
71 Adalimumab
DNA technology inflammatory
Recombinant Fusion protein,
72 Belatacept
DNA technology immunosuppressant
Recombinant Monoclonal antibody, autoimmune
73 Certolizumab pegol
DNA technology diseases
Recombinant Monoclonal antibody, complement
74 Eculizumab
DNA technology inhibitor
Recombinant
75 Etanercept Fusion protein, anti-inflammatory
DNA technology
Recombinant Monoclonal antibody, autoimmune
76 Golimumab
DNA technology diseases
Recombinant Monoclonal antibody, anti-
77 Infliximab
DNA technology inflammatory
Recombinant Monoclonal antibody, multiple
78 Natalizumab
DNA technology sclerosis
Recombinant
79 Rituximab Monoclonal antibody, anticancer
DNA technology
Recombinant Monoclonal antibody, autoimmune
80 Tocilizumab
DNA technology diseases
Recombinant Monoclonal antibody, autoimmune
81 Ustekinumab
DNA technology diseases
Recombinant Monoclonal antibody, autoimmune
82 Vedolizumab
DNA technology diseases
Recombinant
83 Bevacizumab Monoclonal antibody, anticancer
DNA technology
Recombinant
84 Pegaspargase Enzyme therapy, anticancer
DNA technology
Recombinant
85 Anakinra Interleukin-1 receptor antagonist
DNA technology
Recombinant Antisense oligonucleotide,
86 Eteplirsen
DNA technology Duchenne muscular dystrophy
Recombinant Enzyme replacement therapy,
87 Alglucosidase alfa
DNA technology Pompe disease
Serial
Drug Name Synthetic Source Type of Drug
Number
Recombinant Enzyme replacement therapy,
88 Asfotase alfa
DNA technology hypophosphatasia
Recombinant Monoclonal antibody, respiratory
89 Palivizumab
DNA technology syncytial virus
Recombinant
90 Romosozumab Monoclonal antibody, osteoporosis
DNA technology
Monoclonal antibody, acquired
Recombinant
91 Caplacizumab thrombotic thrombocytopenic
DNA technology
purpura
Recombinant Monoclonal antibody, autoimmune
92 Risankizumab
DNA technology diseases
Monoclonal antibody,
Recombinant
93 Satralizumab neuromyelitis optica spectrum
DNA technology
disorder
Recombinant Monoclonal antibody, X-linked
94 Burosumab
DNA technology hypophosphatemia
Sacituzumab Recombinant
95 Antibody-drug conjugate, cancer
govitecan DNA technology
Brentuximab Recombinant
96 Antibody-drug conjugate, cancer
vedotin DNA technology
Trastuzumab Recombinant
97 Antibody-drug conjugate, cancer
emtansine DNA technology
Polatuzumab Recombinant
98 Antibody-drug conjugate, cancer
vedotin DNA technology
Recombinant
99 Enfortumab vedotin Antibody-drug conjugate, cancer
DNA technology
Belantamab Recombinant Antibody-drug conjugate, multiple
100
mafodotin DNA technology myeloma

MINERAL SOURCES
Serial Number Drug Name Source Mineral Type of Drug
1 Magnesium sulfate Magnesium salt Mineral supplement
2 Potassium chloride Potassium salt Electrolyte supplement
3 Sodium chloride Sodium salt Electrolyte supplement
Serial Number Drug Name Source Mineral Type of Drug
4 Calcium carbonate Calcium salt Mineral supplement
5 Iron sulfate Iron salt Mineral supplement
6 Zinc sulfate Zinc salt Mineral supplement
7 Sodium fluoride Sodium salt Dental caries prevention
8 Potassium iodide Potassium salt Iodine supplement
9 Sodium bicarbonate Sodium salt Antacid
10 Aluminum hydroxide Aluminum mineral Antacid
11 Calcium gluconate Calcium salt Mineral supplement
12 Ferrous sulfate Iron salt Iron supplement
13 Zinc oxide Zinc mineral Skin protectant
14 Magnesium hydroxide Magnesium mineral Antacid, laxative
15 Calcium phosphate Calcium salt Mineral supplement
16 Sodium phosphate Sodium salt Electrolyte supplement
17 Sodium bicarbonate Sodium salt Antacid
18 Calcium citrate Calcium salt Mineral supplement
19 Iron dextran Iron mineral Iron supplement
20 Copper sulfate Copper salt Mineral supplement
21 Potassium phosphate Potassium salt Electrolyte supplement
22 Sodium citrate Sodium salt Urinary alkalinizer
23 Calcium lactate Calcium salt Mineral supplement
24 Zinc chloride Zinc salt Mineral supplement
25 Potassium bicarbonate Potassium salt Electrolyte supplement
26 Sodium selenite Sodium salt Selenium supplement
27 Magnesium chloride Magnesium salt Mineral supplement
28 Calcium chloride Calcium salt Electrolyte supplement
29 Iron sucrose Iron mineral Iron supplement
30 Zinc acetate Zinc salt Mineral supplement
31 Sodium phosphate Sodium salt Electrolyte supplement
32 Calcium glucoheptonate Calcium salt Mineral supplement
33 Iron polymaltose complex Iron mineral Iron supplement
34 Potassium phosphate Potassium salt Electrolyte supplement
35 Zinc gluconate Zinc salt Mineral supplement
36 Magnesium oxide Magnesium mineral Laxative, antacid
37 Calcium phosphate Calcium salt Mineral supplement
38 Iron gluconate Iron mineral Iron supplement
39 Zinc sulfate Zinc salt Mineral supplement
40 Sodium chloride Sodium salt Electrolyte supplement
41 Calcium gluconate Calcium salt Mineral supplement
42 Potassium iodide Potassium salt Iodine supplement
43 Magnesium sulfate Magnesium salt Mineral supplement
44 Zinc oxide Zinc mineral Skin protectant
45 Ferrous sulfate Iron salt Iron supplement
46 Calcium carbonate Calcium salt Mineral supplement
Serial Number Drug Name Source Mineral Type of Drug
47 Sodium bicarbonate Sodium salt Antacid
48 Potassium chloride Potassium salt Electrolyte supplement
49 Sodium fluoride Sodium salt Dental caries prevention
50 Aluminum hydroxide Aluminum mineral Antacid
51 Calcium phosphate Calcium salt Mineral supplement
52 Zinc sulfate Zinc salt Mineral supplement
53 Sodium chloride Sodium salt Electrolyte supplement
54 Potassium iodide Potassium salt Iodine supplement
55 Iron sulfate Iron salt Mineral supplement
56 Calcium carbonate Calcium salt Mineral supplement
57 Magnesium hydroxide Magnesium mineral Antacid, laxative
58 Zinc oxide Zinc mineral Skin protectant
59 Sodium bicarbonate Sodium salt Antacid
60 Aluminum hydroxide Aluminum mineral Antacid
61 Calcium gluconate Calcium salt Mineral supplement
62 Ferrous sulfate Iron salt Iron supplement
63 Zinc sulfate Zinc salt Mineral supplement
64 Sodium chloride Sodium salt Electrolyte supplement
65 Potassium chloride Potassium salt Electrolyte supplement
66 Calcium carbonate Calcium salt Mineral supplement
67 Iron sulfate Iron salt Mineral supplement
68 Zinc oxide Zinc mineral Skin protectant
69 Sodium bicarbonate Sodium salt Antacid
70 Magnesium hydroxide Magnesium mineral Antacid, laxative
71 Calcium phosphate Calcium salt Mineral supplement
72 Zinc sulfate Zinc salt Mineral supplement
73 Sodium chloride Sodium salt Electrolyte supplement
74 Potassium iodide Potassium salt Iodine supplement
75 Iron sulfate Iron salt Mineral supplement
76 Calcium carbonate Calcium salt Mineral supplement
77 Magnesium hydroxide Magnesium mineral Antacid, laxative
78 Zinc oxide Zinc mineral Skin protectant
79 Sodium bicarbonate Sodium salt Antacid
80 Potassium chloride Potassium salt Electrolyte supplement
81 Sodium chloride Sodium salt Electrolyte supplement
82 Calcium carbonate Calcium salt Mineral supplement
83 Iron sulfate Iron salt Mineral supplement
84 Zinc oxide Zinc mineral Skin protectant
85 Sodium bicarbonate Sodium salt Antacid
86 Potassium iodide Potassium salt Iodine supplement
87 Calcium phosphate Calcium salt Mineral supplement
88 Magnesium sulfate Magnesium salt Mineral supplement
89 Ferrous sulfate Iron salt Iron supplement
Serial Number Drug Name Source Mineral Type of Drug
90 Zinc sulfate Zinc salt Mineral supplement
91 Sodium chloride Sodium salt Electrolyte supplement
92 Potassium chloride Potassium salt Electrolyte supplement
93 Calcium carbonate Calcium salt Mineral supplement
94 Iron sulfate Iron salt Mineral supplement
95 Zinc oxide Zinc mineral Skin protectant
96 Sodium bicarbonate Sodium salt Antacid
97 Potassium iodide Potassium salt Iodine supplement
98 Calcium phosphate Calcium salt Mineral supplement
99 Magnesium hydroxide Magnesium mineral Antacid, laxative
100 Zinc sulfate Zinc salt Mineral supplement

ANIMAL
Serial
Drug Type Source
No.
1 Insulin Hormone Pancreas of cattle and pigs
Thyroid glands of pigs and
2 Thyroid Hormones Hormones
cows
3 Heparin Anticoagulant Intestines of pigs and cows
Bile Acid
4 Cholestyramine Bile from various animals
Sequestrant
Bovine Serum Albumin
5 Protein Supplement Blood serum of cows
(BSA)
Venom of various snakes
6 Antivenom Antitoxin
(processed in animals)
Plasma from human or animal
7 Antithrombin III Anticoagulant
donors (e.g., pigs)
Skin, bones, and connective
8 Collagen Dermal Filler
tissues of cows and pigs
9 Bovine Bone Powder Bone Graft Material Bones of cows
10 Hylauronidase Enzyme Testes of bulls
Regenerative
11 Placenta Extracts Placenta from cows or pigs
Medicine
Antithymocyte Globulin
12 Immunosuppressant Spleen of rabbits or horses
(ATG)
13 Diphtheria Antitoxin Antitoxin Serum from horses
Serial
Drug Type Source
No.
14 Tetanus Antitoxin Antitoxin Serum from horses
Rabies Immune
15 Antiviral Serum from horses
Globulin
Processed toxin from
Botulinum Toxin
16 Neurotoxin Clostridium bacteria (animal
(Botox)
testing involved)
17 Protamine Sulfate Anticoagulant Testes of salmon
Recombinant, originally
18 Erythropoietin Hormone derived from animals (mice,
rabbits)
Recombinant, originally
19 Leptin Hormone
derived from animal models
Plasma from human donors
20 Factor VIII Coagulation Factor (sometimes sourced from
animal models)
Plasma from human donors
21 Factor IX Coagulation Factor (sometimes sourced from
animal models)
Extracted from parathyroid
22 Parathyroid Hormone Hormone
glands of cows or pigs
Thyroid glands of salmon or
23 Calcitonin Hormone
pigs
Extracted from testes of
24 Testosterone Hormone
animals or synthesized
Extracted from ovaries of
25 Estrogen Hormone
animals or synthesized
Extracted from ovaries of
26 Progesterone Hormone
animals or synthesized
Extracted from the posterior
27 Oxytocin Hormone
pituitary glands of animals
Extracted from the posterior
28 Vasopressin Hormone
pituitary glands of animals
Plasma from human donors
Rho(D) Immune
29 Immunoglobulin (sometimes animal models
Globulin
used in development)
Monoclonal Hybridoma technology
30 Monoclonal Antibodies
Antibodies involving mice
Immunoglobulins (IgG, Plasma from human or animal
31 Antibodies
IgA, IgM) donors
32 Cortisol Hormone Adrenal glands of cows or pigs
Synthesized or extracted from
33 Hydrocortisone Anti-inflammatory
adrenal glands of animals
Adrenaline
34 Hormone Adrenal glands of animals
(Epinephrine)
35 Dexamethasone Anti-inflammatory Synthetic or derived from
Serial
Drug Type Source
No.
animal models
36 Chymotrypsin Enzyme Pancreas of cattle
37 Trypsin Enzyme Pancreas of cattle
38 Pepsin Enzyme Stomach lining of pigs or cattle
39 Lipase Enzyme Pancreas of cattle or pigs
40 Amylase Enzyme Pancreas of cattle or pigs
Papaya latex (often used in
41 Papain Enzyme
animals for testing)
Pineapple stem (animal testing
42 Bromelain Enzyme
involved)
Kidney tissue of humans or
43 Urokinase Thrombolytic
animals
Plasma from human or animal
44 Alpha-1 Antitrypsin Protein
donors
Bovine Growth
45 Hormone Pituitary gland of cattle
Hormone (BGH)
Recombinant, originally
46 Erythropoietin (EPO) Hormone
animal-derived
Extracted from pancreatic
47 Somatostatin Hormone
tissue of animals
Thyroid glands of salmon or
48 Calcitonin Hormone
cows
GnRH (Gonadotropin-
49 Hormone Hypothalamus of animals
Releasing Hormone)
Luteinizing Hormone
50 Hormone Pituitary gland of animals
(LH)
Follicle-Stimulating
51 Hormone Pituitary gland of animals
Hormone (FSH)
Extracted from placenta or
52 Relaxin Hormone
uterus of animals
53 Prolactin Hormone Pituitary gland of animals
54 Angiotensin II Hormone Plasma from animal models
55 Neurotensin Neurotransmitter Brain tissue of animals
Extracted from blood vessels of
56 Endothelin Peptide
animals
Synthesized or derived from
57 Apomorphine Dopamine Agonist
animal models
Bovine Serum Albumin
58 Protein Blood serum of cows
(BSA)
59 Antimicrobial Peptides Antimicrobial Various animal tissues
Immunoglobulin G Plasma from human or animal
60 Antibody
(IgG) donors
Synthesized or extracted from
61 Corticosteroids Anti-inflammatory
adrenal glands of animals
Serial
Drug Type Source
No.
62 Myeloperoxidase Enzyme White blood cells of animals
Plasma from human or animal
63 Factor VII Coagulation Factor
donors
Plasma from human or animal
64 Factor XIII Coagulation Factor
donors
65 P450 Enzymes Enzyme Liver tissues of animals
Plasma from human or animal
66 Hageman Factor Coagulation Factor
donors
Tissue Plasminogen Plasma from human or animal
67 Thrombolytic
Activator (tPA) donors
68 Fibronectin Protein Plasma or tissues from animals
69 Sialidase Enzyme Saliva of animals
Kidney tissue of humans or
70 Urokinase Thrombolytic
animals
71 Hystatin Antimicrobial Saliva of various animals
72 Glucagon Hormone Pancreas of pigs or cattle
Thyroid glands of salmon or
73 Calcitonin Hormone
pigs
Luteinizing Hormone
74 Hormone Pituitary gland of animals
(LH)
Follicle-Stimulating
75 Hormone Pituitary gland of animals
Hormone (FSH)
Extracted from placenta or
76 Relaxin Hormone
uterus of animals
77 Prolactin Hormone Pituitary gland of animals
78 Angiotensin II Hormone Plasma from animal models
79 Neurotensin Neurotransmitter Brain tissue of animals
Extracted from blood vessels of
80 Endothelin Peptide
animals
Synthesized or derived from
81 Apomorphine Dopamine Agonist
animal models
Plasma from human or animal
82 Antithrombin III Anticoagulant
donors
Plasma from human or animal
83 Alpha-1 Antitrypsin Protein
donors
Bovine Growth
84 Hormone Pituitary gland of cattle
Hormone (BGH)
Recombinant, originally
85 Erythropoietin (EPO) Hormone
animal-derived
Extracted from pancreatic
86 Somatostatin Hormone
tissue of animals
GnRH (Gonadotropin-
87 Hormone Hypothalamus of animals
Releasing Hormone)
88 Relaxin Hormone Extracted from placenta or
Serial
Drug Type Source
No.
uterus of animals
89 Prolactin Hormone Pituitary gland of animals
90 Neurotensin Neurotransmitter Brain tissue of animals
Extracted from blood vessels of
91 Endothelin Peptide
animals
Synthesized or derived from
92 Apomorphine Dopamine Agonist
animal models
93 Antimicrobial Peptides Antimicrobial Various animal tissues
94 Myeloperoxidase Enzyme White blood cells of animals
Plasma from human or animal
95 Factor VII Coagulation Factor
donors
Plasma from human or animal
96 Factor XIII Coagulation Factor
donors
97 P450 Enzymes Enzyme Liver tissues of animals
Plasma from human or animal
98 Hageman Factor Coagulation Factor
donors
Tissue Plasminogen Plasma from human or animal
99 Thrombolytic
Activator (tPA) donors
100 Fibronectin Protein Plasma or tissues from animals
 DNA RECOMBINANT TECHNOLOGY
Serial
Drug Name Type Source
No.
1 Insulin Hormone E. coli
Chinese Hamster
2 Erythropoietin (EPO) Hormone Ovary (CHO)
cells
Human Growth Hormone E. coli or CHO
3 Hormone
(HGH) cells
4 Factor VIII Blood Coagulation Factor CHO cells
5 Factor IX Blood Coagulation Factor CHO cells
E. coli or CHO
6 Interferon-alpha Antiviral
cells
7 Interferon-beta Antiviral CHO cells
E. coli or CHO
8 Interferon-gamma Immunomodulator
cells
9 Monoclonal Antibodies Anticancer, Immunotherapy CHO cells
10 Trastuzumab (Herceptin) Monoclonal Antibody CHO cells
11 Rituximab (Rituxan) Monoclonal Antibody CHO cells
12 Adalimumab (Humira) Monoclonal Antibody CHO cells
13 Bevacizumab (Avastin) Monoclonal Antibody CHO cells
14 Infliximab (Remicade) Monoclonal Antibody CHO cells
Granulocyte Colony-Stimulating
15 Filgrastim (Neupogen) E. coli
Factor
Granulocyte Colony-Stimulating
16 Pegfilgrastim (Neulasta) CHO cells
Factor
17 Glucagon Hormone E. coli
Hematopoietic Stem Cell
18 Hematopoietic Growth Factor CHO cells
Factor
19 Denosumab Monoclonal Antibody CHO cells
20 Natalizumab (Tysabri) Monoclonal Antibody CHO cells
21 Ipilimumab (Yervoy) Monoclonal Antibody CHO cells
22 Nivolumab (Opdivo) Monoclonal Antibody CHO cells
Pembrolizumab
23 Monoclonal Antibody CHO cells
(Keytruda)
24 Abatacept (Orencia) Fusion Protein CHO cells
25 Etanercept (Enbrel) Fusion Protein CHO cells
26 Alemtuzumab (Campath) Monoclonal Antibody CHO cells
27 Panitumumab (Vectibix) Monoclonal Antibody CHO cells
Certolizumab pegol
28 Monoclonal Antibody CHO cells
(Cimzia)
Serial
Drug Name Type Source
No.
Thrombopoietin Receptor
29 Romiplostim (Nplate) CHO cells
Agonist
30 Eculizumab (Soliris) Monoclonal Antibody CHO cells
31 Dupilumab (Dupixent) Monoclonal Antibody CHO cells
32 Emicizumab (Hemlibra) Monoclonal Antibody CHO cells
33 Fostamatinib (Tavalisse) Tyrosine Kinase Inhibitor E. coli
34 Laronidase (Aldurazyme) Enzyme Replacement Therapy CHO cells
35 Idursulfase (Elaprase) Enzyme Replacement Therapy CHO cells
Velaglucerase alfa
36 Enzyme Replacement Therapy CHO cells
(Vpriv)
Taliglucerase alfa
37 Enzyme Replacement Therapy CHO cells
(Elelyso)
38 Alglucerase (Cerezyme) Enzyme Replacement Therapy CHO cells
39 Pegaspargase (Oncaspar) Enzyme Replacement Therapy E. coli
40 Migalastat (Galafold) Chaperone Therapy CHO cells
41 Lumasiran (Oxlumo) RNAi Therapeutic CHO cells
42 Inclisiran (Leqvio) RNAi Therapeutic CHO cells
43 Aflibercept (Eylea) Fusion Protein CHO cells
44 Anifrolumab (Saphnelo) Monoclonal Antibody CHO cells
Tisagenlecleucel
45 CAR-T Cell Therapy CHO cells
(Kymriah)
Axicabtagene ciloleucel
46 CAR-T Cell Therapy CHO cells
(Yescarta)
Brexucabtagene
47 CAR-T Cell Therapy CHO cells
autoleucel (Tecartus)
Abecma (Idecabtagene
48 CAR-T Cell Therapy CHO cells
vicleucel)
Zolgensma
49 (onasemnogene Gene Therapy CHO cells
abeparvovec)
Luxturna (voretigene
50 Gene Therapy CHO cells
neparvovec)
Kymriah
51 CAR-T Cell Therapy CHO cells
(tisagenlecleucel)
Imlygic (talimogene
52 Oncolytic Virus Therapy CHO cells
laherparepvec)
Dual Angiotensin Receptor and
53 Sparsentan CHO cells
Endothelin Receptor Antagonist
54 Luspatercept (Reblozyl) Erythroid Maturation Agent CHO cells
55 Selpercatinib (Retevmo) Tyrosine Kinase Inhibitor CHO cells
56 Entrectinib (Rozlytrek) Tyrosine Kinase Inhibitor CHO cells
57 Lorbrena (lorlatinib) Tyrosine Kinase Inhibitor CHO cells
58 Avapritinib (Ayvakit) Tyrosine Kinase Inhibitor CHO cells
Serial
Drug Name Type Source
No.
59 Ripretinib (Qinlock) Tyrosine Kinase Inhibitor CHO cells
60 Capmatinib (Tabrecta) Tyrosine Kinase Inhibitor CHO cells
61 Elranatamab (Elra) Monoclonal Antibody CHO cells
62 Talquetamab (Tal) Monoclonal Antibody CHO cells
63 Sotorasib (Lumakras) KRAS Inhibitor CHO cells
Amgen's AMG 510
64 KRAS Inhibitor CHO cells
(sotorasib)
Tislelizumab (BGB-
65 Monoclonal Antibody CHO cells
A317)
66 Sintilimab (Tyvyt) Monoclonal Antibody CHO cells
67 Toripalimab (Tuoyi) Monoclonal Antibody CHO cells
68 Ziv-aflibercept (Zaltrap) Fusion Protein CHO cells
69 Daratumumab (Darzalex) Monoclonal Antibody CHO cells
70 Isunakinra (Kineret) IL-1 Receptor Antagonist E. coli
71 Fitusiran (FITUSIRAN) RNAi Therapeutic CHO cells
72 Mepolizumab (Nucala) Monoclonal Antibody CHO cells
73 Reslizumab (Cinqair) Monoclonal Antibody CHO cells
74 Benralizumab (Fasenra) Monoclonal Antibody CHO cells
75 Dupilumab (Dupixent) Monoclonal Antibody CHO cells
76 Secukinumab (Cosentyx) Monoclonal Antibody CHO cells
77 Ixekizumab (Taltz) Monoclonal Antibody CHO cells
78 Ustekinumab (Stelara) Monoclonal Antibody CHO cells
79 Guselkumab (Tremfya) Monoclonal Antibody CHO cells
80 Risankizumab (Skyrizi) Monoclonal Antibody CHO cells
81 Vespid (Paxlovid) Antiviral CHO cells
82 Remdesivir (Veklury) Antiviral CHO cells
83 Sirema (Cemiplimab) Monoclonal Antibody CHO cells
84 Leniolisib (Leniolisib) PI3K Inhibitor CHO cells
85 Satralizumab (Enspryng) Monoclonal Antibody CHO cells
86 Ofatumumab (Arzerra) Monoclonal Antibody CHO cells
87 Panobinostat (Farydak) Histone Deacetylase Inhibitor E. coli
Belantamab mafodotin
88 Antibody-Drug Conjugate CHO cells
(Blenrep)
Polatuzumab vedotin
89 Antibody-Drug Conjugate CHO cells
(Polivy)
Enfortumab vedotin
90 Antibody-Drug Conjugate CHO cells
(Padcev)
91 Tazemetostat (Tazverik) EZH2 Inhibitor CHO cells
92 Ripretinib (Qinlock) Tyrosine Kinase Inhibitor CHO cells
93 Selumetinib (Koselugo) MEK Inhibitor CHO cells
94 Brigatinib (Alunbrig) Tyrosine Kinase Inhibitor CHO cells
95 Lorlatinib (Lorbrena) Tyrosine Kinase Inhibitor CHO cells
Serial
Drug Name Type Source
No.
Acalabrutinib Bruton's Tyrosine Kinase
96 CHO cells
(Calquence) Inhibitor
Bruton's Tyrosine Kinase
97 Zanubrutinib (Brukinsa) CHO cells
Inhibitor
98 ivosidenib (Tibsovo) IDH1 Inhibitor CHO cells
99 enasidenib (Idhifa) IDH2 Inhibitor CHO cells
100 Olaparib (Lynparza) PARP Inhibitor CHO cells