Functions of Hypothalamus
The hypothalamus is a small but crucial part of the brain that acts as the center for homeostasis and integrates
endocrine and autonomic functions.
1. Endocrine Functions:
- Controls secretion of anterior pituitary hormones by releasing and inhibiting hormones:
• Releasing hormones: TRH, CRH, GnRH, GHRH
• Inhibiting hormones: Somatostatin, Dopamine (inhibits prolactin)
- Produces posterior pituitary hormones (stored in posterior pituitary):
• ADH (Vasopressin) → water balance
• Oxytocin → uterine contraction & milk ejection
2. Regulation of Autonomic Nervous System:
- Controls sympathetic and parasympathetic activities:
• Heart rate
• Blood pressure
• Digestive motility
• Pupillary responses
3. Regulation of Body Temperature:
- Acts as a thermostat for the body:
• Anterior hypothalamus: Heat loss center (vasodilation, sweating)
• Posterior hypothalamus: Heat conservation (vasoconstriction, shivering)
4. Regulation of Hunger and Satiety:
- Lateral hypothalamus: Hunger center (lesion → anorexia)
- Ventromedial hypothalamus: Satiety center (lesion → obesity)
5. Regulation of Water Balance:
- Controls thirst (via osmoreceptors in supraoptic and paraventricular nuclei)
- Secretes ADH for water reabsorption in kidneys
6. Regulation of Sleep and Wakefulness:
- Suprachiasmatic nucleus acts as the biological clock for circadian rhythms
- Influences sleep-wake cycle
7. Emotional and Behavioral Regulation:
- Part of limbic system → controls emotions like fear, anger, sexual behavior
Summary Table: Functions of Hypothalamus
| Function | Center/Nucleus Involved |
|--------------------------|-----------------------------------------------|
| Endocrine control | Supraoptic & paraventricular nuclei |
| ANS regulation | Various hypothalamic nuclei |
| Temperature regulation | Anterior (heat loss), posterior (heat gain) |
| Hunger & satiety | Lateral (hunger), Ventromedial (satiety) |
| Water balance | Supraoptic & paraventricular nuclei |
| Circadian rhythm | Suprachiasmatic nucleus |
| Emotions & behavior | Limbic connections |
Flowchart: Functions of Hypothalamus
Hypothalamus
↓
Endocrine Control → Pituitary Hormones (ADH, Oxytocin)
↓
Autonomic Control → Heart Rate, BP, Digestion
↓
Homeostasis → Temp, Hunger, Thirst, Sleep
↓
Behavioral & Emotional Responses