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CISR

CRISPR-Cas9 is a revolutionary gene-editing technology that allows for precise modifications to DNA using the Cas9 enzyme as molecular scissors. Its applications span medicine, agriculture, and research, including correcting genetic disorders and engineering resilient crops. However, ethical concerns regarding human germline editing and its societal implications are prompting the development of global guidelines.

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14 views1 page

CISR

CRISPR-Cas9 is a revolutionary gene-editing technology that allows for precise modifications to DNA using the Cas9 enzyme as molecular scissors. Its applications span medicine, agriculture, and research, including correcting genetic disorders and engineering resilient crops. However, ethical concerns regarding human germline editing and its societal implications are prompting the development of global guidelines.

Uploaded by

aaipappi1
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as TXT, PDF, TXT or read online on Scribd
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CRISPR-Cas9: Revolutionizing Gene Editing


Introduction
CRISPR-Cas9 is a groundbreaking gene-editing technology that enables precise,
targeted changes to DNA. Derived from a natural defense mechanism in bacteria,
CRISPR stands for “Clustered Regularly Interspaced Short Palindromic Repeats.”

Mechanism
Cas9 is an enzyme that acts as molecular scissors, guided by RNA to specific DNA
sequences. Once bound, it cuts the DNA, allowing for insertion, deletion, or
replacement of genetic material.

Applications

Medicine: Correcting genetic disorders like sickle cell anemia.

Agriculture: Engineering pest-resistant or drought-tolerant crops.

Research: Creating gene knockouts to study disease mechanisms.

Ethical Considerations
The potential for human germline editing raises concerns about designer babies,
inequality, and long-term effects. Global guidelines are evolving to address these
issues.

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