ACUTE TONSILLOPHARINGITIS
Waldeyer ring comprises the palatine tonsils, the pharyngeal tonsil or adenoid, lymphoid tissue surrounding the eustachian tube orifice in the
lateral walls of the nasopharynx, the lingual tonsil at the base of the tongue, and scattered lymphoid tissue throughout the remainder of the
pharynx, particularly behind the posterior pharyngeal pillars and along the posterior pharyngeal wall
Palatine tonsil consists of lymphoid tissue located between the palatoglossal fold (anterior tonsillar pillar) and the palatopharyngeal fold (posterior
tonsillar pillar) forms
Lingual tonsil Formed by the lymphoid tissue at the base of the tongue that also contains simple tonsillar crypts.
Adenoid is a single aggregation of lymphoid tissue that occupies the space between the nasal septum and the posterior pharyngeal wall.
                                                                       PATHOLOGY
                              Acute Infection                                                                    Chronic Infection
Causes: Mostly are Viruses                                                       Causes: β-lactamase–producing organisms
GABHS - most common cause of bacterial infection in the pharynx                          Aerobes: Streptococci, Haemophilus influenzae
                                                                                         Anaerobes: Peptostreptococcus, Prevotella, and Fusobacterium
                                                                                 Cryptic tonsillitis - tonsillar crypts can accumulate desquamated
                                                                                 epithelial cells, lymphocytes, bacteria, and other debris.
                                                                                 Tonsillolith or tonsillar concretions - calcified cryptic plugs
                                                                CLINICAL MANIFESTATIONS
GABHS infection: odynophagia, dry throat, malaise, fever and chills,             S/Sx: halitosis, chronic sore throats, foreign-body sensation, or a history
dysphagia, referred otalgia, headache, muscular aches, and enlarged              of expelling foul-tasting and foul-smelling cheesy lumps.
cervical nodes. Signs include dry tongue, erythematous enlarged tonsils, PE: tonsils of a range of sizes which often they contain copious debris
tonsillar or pharyngeal exudate, palatine petechiae, and enlargement             within the crypts.
and tenderness of the jugulodigastric lymph nodes
Viral: Gradual onset
Moderate throat pain
Symptoms of URTI
HSV: vesicles and ulcers
Adenovirus: Conjunctivitis
                                                                         DIAGNOSIS
Throat Culture                           Gold standard for diagnosing GABHS Pharyngitis
RADT                                     Dx of GABHS pharyngitis
Rapid Antigen detection test             Less sensitive than culture
                                         >95% specificity
                                             (+) culture is unnecessary
                                             (-) Do throat culture
                                                                      MANAGEMENT
 Antibiotics for Penicillin 10days                                     250mg (<27kg) or 500mg (>27kg) 2x/day
    GABHS           Amoxicillin 10days                                 50mg/kg PO
                                  Allergic to Penicillin
                    Erythromycin 10 days                               40mg/kg/day PO 2x. Max 1g/day
                    Azithromycin                                       Day 1: 12mg/kg
                                                                       Day2-5: 6mg/kg 1x/day; Max 500mg/day
                    Clarithromycin 10 days                             15mg/kg/day 2x /day; Max: 500mg/day
                    Clindamycin        10 days                         20mg/kg/day PO 3x/day; Max 1.8g/day
                        Start antibiotics immediately even w/o         - Scarlet fever
                                         culture                       - Household ontact with Streptococcal pharyngitis
                                                                       - Hx of acute Rheumatic fever
                                                                       - Family hx of acute rheumatic fever
Tonsillectomy       Recurrent streptococcal pharyngitis that is culture positive strep pharyngitis
                    Paradise Criteria:
                       ≥ 7 episodes in the previous year
                       ≥ 5 episodes in each of the preceding 2 years
                       ≥ 3 episodes in each of the preceding 3 year
                                                                      COMPLICATIONS
  Rheumatic fever
  Post- Streptococcal glomerulonephritis
  Peritonsillar/retropharyngeal abscess