SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Trade name : Zemea® Propanediol
Substance name : Propane-1,3-diol
EC-No. : 207-997-3
1.2 Relevant identified uses of the substance or mixture and uses advised against
Use of the Sub- : Industrial use, Cosmetics, Solvent, Fragrances, Personal
stance/Mixture care, Washing and cleaning products (including solvent based
products), Polymer, Monomer
Recommended restrictions : For industrial use only., Do not use product for anything out-
on use side of the above specified uses, Do not use CovationBioPDO
materials in medical applications involving implantation in the
human body or contact with internal body fluids or tissues
unless the material has been provided from CovationBioPDO
under a written contract that is consistent with CovationBi-
oPDO policy regarding medical applications and expressly
acknowledges the contemplated use. For further information,
please contact your CovationBioPDO representative. You may
also request a copy of the CovationBioPDO POLICY Regard-
ing Medical Applications and CovationBioPDO CAUTION
Regarding Medical Applications.
1.3 Details of the supplier of the safety data sheet
Company : Dr. Knoell Consult Ltd
22 Cathedral Road
CF11 9LJ Cardiff, United Kingdom
Telephone : +1 866 404 7933
E-mail address of person :
responsible for the SDS
1.4 Emergency telephone number
+44 20 35147487
Access Code 335772
1 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Classification (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK
SI 2019/720, and UK SI 2020/1567)
Not a hazardous substance or mixture.
2.2 Label elements
Labelling (REGULATION (EC) No 1272/2008) as amended by GB-CLP Regulation, UK SI
2019/720, and UK SI 2020/1567)
Not a hazardous substance or mixture.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumula-
tive and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or
higher.
SECTION 3: Composition/information on ingredients
3.1 Substances
Substance name : Propane-1,3-diol
EC-No. : 207-997-3
Components
No hazardous ingredients
SECTION 4: First aid measures
4.1 Description of first aid measures
Protection of first-aiders : No special precautions are necessary for first aid responders.
If inhaled : If inhaled, remove to fresh air.
Get medical attention if symptoms occur.
In case of skin contact : Wash with water and soap as a precaution.
Get medical attention if symptoms occur.
In case of eye contact : Flush eyes with water as a precaution.
Get medical attention if irritation develops and persists.
If swallowed : If swallowed, DO NOT induce vomiting.
Get medical attention if symptoms occur.
Rinse mouth thoroughly with water.
2 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
4.2 Most important symptoms and effects, both acute and delayed
None known.
4.3 Indication of any immediate medical attention and special treatment needed
Treatment : Treat symptomatically and supportively.
SECTION 5: Firefighting measures
5.1 Extinguishing media
Suitable extinguishing media : Water spray
Alcohol-resistant foam
Carbon dioxide (CO2)
Dry chemical
Unsuitable extinguishing : None known.
media
5.2 Special hazards arising from the substance or mixture
Specific hazards during fire- : Exposure to combustion products may be a hazard to health.
fighting
Hazardous combustion prod- : Carbon oxides
ucts
5.3 Advice for firefighters
Special protective equipment : Wear self-contained breathing apparatus for firefighting if nec-
for firefighters essary. Use personal protective equipment.
Specific extinguishing meth- : Use extinguishing measures that are appropriate to local cir-
ods cumstances and the surrounding environment.
Use water spray to cool unopened containers.
Remove undamaged containers from fire area if it is safe to do
so.
Evacuate area.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal precautions : Follow safe handling advice (see section 7) and personal pro-
tective equipment recommendations (see section 8).
6.2 Environmental precautions
Environmental precautions : Avoid release to the environment.
Prevent further leakage or spillage if safe to do so.
Prevent spreading over a wide area (e.g. by containment or oil
barriers).
Retain and dispose of contaminated wash water.
3 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
Local authorities should be advised if significant spillages
cannot be contained.
6.3 Methods and material for containment and cleaning up
Methods for cleaning up : Soak up with inert absorbent material.
For large spills, provide dyking or other appropriate contain-
ment to keep material from spreading. If dyked material can
be pumped, store recovered material in appropriate container.
Clean up remaining materials from spill with suitable absor-
bent.
Local or national regulations may apply to releases and dis-
posal of this material, as well as those materials and items
employed in the cleanup of releases. You will need to deter-
mine which regulations are applicable.
Sections 13 and 15 of this SDS provide information regarding
certain local or national requirements.
6.4 Reference to other sections
See sections: 7, 8, 11, 12 and 13.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Technical measures : See Engineering measures under EXPOSURE
CONTROLS/PERSONAL PROTECTION section.
Local/Total ventilation : Use only with adequate ventilation.
Advice on safe handling : Handle in accordance with good industrial hygiene and safety
practice, based on the results of the workplace exposure as-
sessment
Take care to prevent spills, waste and minimize release to the
environment.
Hygiene measures : If exposure to chemical is likely during typical use, provide eye
flushing systems and safety showers close to the working
place. When using do not eat, drink or smoke. Wash contami-
nated clothing before re-use.
7.2 Conditions for safe storage, including any incompatibilities
Requirements for storage : Keep in properly labelled containers. Store in accordance with
areas and containers the particular national regulations.
Advice on common storage : Do not store with the following product types:
Strong oxidizing agents
Gases
7.3 Specific end use(s)
Specific use(s) : No data available
4 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Contains no substances with occupational exposure limit values.
Derived No Effect Level (DNEL):
Substance name End Use Exposure routes Potential health ef- Value
fects
Propane-1,3-diol Workers Inhalation Long-term systemic 12 mg/m3
effects
Workers Skin contact Long-term systemic 200 mg/kg
effects bw/day
Consumers Inhalation Long-term systemic 3 mg/m3
effects
Consumers Skin contact Long-term systemic 100 mg/kg
effects bw/day
Consumers Ingestion Long-term systemic 5 mg/kg
effects bw/day
Predicted No Effect Concentration (PNEC):
Substance name Environmental Compartment Value
Propane-1,3-diol Fresh water 7.417 mg/l
Marine water 0.7417 mg/l
Intermittent use/release 74.17 mg/l
Sewage treatment plant 6000 mg/l
Fresh water sediment 26.96 mg/kg
Soil 1.488 mg/kg
8.2 Exposure controls
Engineering measures
Ensure adequate ventilation, especially in confined areas.
Minimize workplace exposure concentrations.
Personal protective equipment
Eye/face protection : Wear the following personal protective equipment:
Safety glasses
Equipment should conform to BS EN 166
Hand protection
Remarks : Wash hands before breaks and at the end of workday.
Skin and body protection : Skin should be washed after contact.
Respiratory protection : If adequate local exhaust ventilation is not available or expo-
sure assessment demonstrates exposures outside the rec-
ommended guidelines, use respiratory protection.
Equipment should conform to BS EN 14387
5 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
Filter type : Organic vapour type (A)
SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
Appearance : liquid
Colour : transparent
Odour : slight
Odour Threshold : No data available
pH : No data available
Melting point/freezing point : ca. -27.65 °C
Initial boiling point and boiling : ca. 214.22 °C
range
Flash point : 129 °C
Method: Cleveland open cup
Evaporation rate : No data available
Flammability (solid, gas) : Not applicable
Upper explosion limit / Upper : No data available
flammability limit
Lower explosion limit / Lower : ca. 2.6 %(V)
flammability limit Information taken from reference works and the literature.
Vapour pressure : ca. 0.0267 hPa (25 °C)
Information taken from reference works and the literature.
Relative vapour density : No data available
Relative density : ca. 1.053
Density : No data available
Solubility(ies)
Water solubility : completely soluble
Partition coefficient: n- : log Pow: ca. -1.04
octanol/water Information taken from reference works and the literature.
Auto-ignition temperature : 400 °C
Decomposition temperature : > 129 °C
6 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
Viscosity
Viscosity, dynamic : ca. 49 mPa.s (20 °C)
Viscosity, kinematic : ca. 46 mm2/s (20 °C)
Information taken from reference works and the literature.
Explosive properties : Not explosive
Oxidizing properties : The substance or mixture is not classified as oxidizing.
9.2 Other information
Flammability (liquids) : No data available
Particle size : Not applicable
SECTION 10: Stability and reactivity
10.1 Reactivity
Not classified as a reactivity hazard.
10.2 Chemical stability
Stable under normal conditions.
10.3 Possibility of hazardous reactions
Hazardous reactions : Can react with strong oxidizing agents.
10.4 Conditions to avoid
Conditions to avoid : None known.
10.5 Incompatible materials
Materials to avoid : Oxidizing agents
10.6 Hazardous decomposition products
No hazardous decomposition products are known.
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Information on likely routes of : Inhalation
exposure Skin contact
Ingestion
Eye contact
Acute toxicity
Not classified based on available information.
7 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
Skin corrosion/irritation
Not classified based on available information.
Serious eye damage/eye irritation
Not classified based on available information.
Respiratory or skin sensitisation
Skin sensitisation
Not classified based on available information.
Respiratory sensitisation
Not classified based on available information.
Germ cell mutagenicity
Not classified based on available information.
Carcinogenicity
Not classified based on available information.
Reproductive toxicity
Not classified based on available information.
STOT - single exposure
Not classified based on available information.
STOT - repeated exposure
Not classified based on available information.
Aspiration toxicity
Not classified based on available information.
SECTION 12: Ecological information
12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
Product:
Assessment : This substance/mixture contains no components considered
to be either persistent, bioaccumulative and toxic (PBT), or
very persistent and very bioaccumulative (vPvB) at levels of
0.1% or higher.
8 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
12.6 Endocrine disrupting properties
Product:
Assessment : The substance/mixture does not contain components consid-
ered to have endocrine disrupting properties according to
REACH Article 57(f) or Commission Delegated regulation
(EU) 2017/2100 or Commission Regulation (EU) 2018/605 at
levels of 0.1% or higher.
12.7 Other adverse effects
No data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Product : Dispose of in accordance with local regulations.
According to the European Waste Catalogue, Waste Codes
are not product specific, but application specific.
Waste codes should be assigned by the user, preferably in
discussion with the waste disposal authorities.
Contaminated packaging : Empty containers should be taken to an approved waste han-
dling site for recycling or disposal.
If not otherwise specified: Dispose of as unused product.
SECTION 14: Transport information
14.1 UN number
ADN : Not regulated as a dangerous good
ADR : Not regulated as a dangerous good
RID : Not regulated as a dangerous good
IMDG : Not regulated as a dangerous good
IATA : Not regulated as a dangerous good
14.2 UN proper shipping name
ADN : Not regulated as a dangerous good
ADR : Not regulated as a dangerous good
RID : Not regulated as a dangerous good
IMDG : Not regulated as a dangerous good
IATA : Not regulated as a dangerous good
14.3 Transport hazard class(es)
ADN : Not regulated as a dangerous good
9 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
ADR : Not regulated as a dangerous good
RID : Not regulated as a dangerous good
IMDG : Not regulated as a dangerous good
IATA : Not regulated as a dangerous good
14.4 Packing group
ADN : Not regulated as a dangerous good
ADR : Not regulated as a dangerous good
RID : Not regulated as a dangerous good
IMDG : Not regulated as a dangerous good
IATA (Cargo) : Not regulated as a dangerous good
IATA (Passenger) : Not regulated as a dangerous good
14.5 Environmental hazards
Not regulated as a dangerous good
14.6 Special precautions for user
Not applicable
14.7 Transport in bulk according to Annex II of Marpol and the IBC Code
Remarks : Not applicable for product as supplied.
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mix-
ture
Relevant EU provisions transposed through retained EU law
UK REACH List of restrictions (Annex 17) : Not applicable
UK REACH Candidate list of substances of very high : Not applicable
concern (SVHC) for Authorisation
The Persistent Organic Pollutants Regulations (retained : Not applicable
Regulation (EU) 2019/1021 as amended for Great Brit-
ain)
Regulation (EC) No 1005/2009 on substances that de- : Not applicable
plete the ozone layer
UK REACH List of substances subject to authorisation : Not applicable
(Annex XIV)
GB Export and import of hazardous chemicals - Prior : Not applicable
Informed Consent (PIC) Regulation
Control of Major Accident Hazards Regulations 2015 (COMAH)
Not applicable
10 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
Volatile organic compounds : Directive 2010/75/EU of 24 November 2010 on industrial
emissions (integrated pollution prevention and control)
Remarks: no VOC duties
15.2 Chemical safety assessment
A Chemical Safety Assessment has not been carried out.
SECTION 16: Other information
Other information : Items where changes have been made to the previous version
are highlighted in the body of this document by two vertical
lines.
Full text of other abbreviations
ADN - E uropean Agreement concerning the International Carriage of Dangerous Goods by Inland
Waterways; ADR - Agreement concerning the International Carriage of Dangerous Goods by
Road; AIIC - Australian Inventory of Industrial Chemicals; ASTM - American Society for the Test-
ing of Materials; bw - Body weight; CLP - Classification Labelling Packaging Regulation; Regula-
tion (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard
of the German Institute for Standardis ation; DS L - Domestic Substances List (Canada); ECHA -
European Chemicals Agency; EC-Number - European Community number; ECx - Concentration
associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergen-
cy Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration as-
sociated with x% growth rate response; GHS - Globally Harmonized System; GLP - Good La-
boratory Practice; IARC - International Agency for Research on Cancer; IA TA - International Air
Trans port Association; IBC - International Code for the Construction and Equipment of S hips car-
rying Dangerous Chemicals in B ulk; IC50 - Half maximal inhibitory concent ration; ICAO - Interna-
tional Civil A viation Organization; IECS C - Inventory of Existing Chemical Substances in China;
IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL
- Industrial Safety and Health Law (Japan); ISO - Int ernational Organisation for Standardization;
KECI - Korea Existing Chemicals Invent ory; LC50 - Lethal Concentration to 50 % of a test popula-
tion; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - Interna-
tional Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified;
NO(A )EC - No Observed (Adverse) E ffect Concentration; NO(A )EL - No Observed (Adverse) Ef-
fect Level; NOE LR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory of
Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office
of Chemical Safety and Pollution P revention; PB T - P ersistent, Bioaccumulative and Toxic sub-
stance; PICCS - Philippines Invent ory of Chemicals and Chemical Substances; (Q)SA R - (Quanti-
tative) Structure Activity Relationship; REA CH - Regulation (E C) No 1907/2006 of the European
Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Re-
striction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous
Goods by Rail; SADT - Self-Accelerating Dec omposition Temperature; SDS - Safety Data Sheet;
SVHC - S ubstance of very high concern; TCSI - Taiwan Chemical S ubstance Inventory; TE CI -
Thailand Existing Chemicals Inventory; TS CA - Toxic Substances Control Act (United States); UN
- United Nations; UNRTDG - United Nations Recommendations on the Trans port of Dangerous
Goods; vPvB - Very Persistent and Very Bioaccumulative
Further information
Sources of key data used to : Internal technical data, data from raw material SDSs, OECD
11 / 12
SAFETY DATA SHEET
According to REACH Regulation (EC) No 1907/2006, as amended by
UK REACH Regulations SI 2019/758
Zemea® Propanediol
Version Revision Date: SDS Number: Date of last issue: 30.08.2022
2.0 30.08.2022 10772266-00002 Date of first issue: 01.06.2022
compile the Safety Data eChem Portal search results and European Chemicals Agen-
Sheet cy, http://echa.europa.eu/
Items where changes have been made to the previous version are highlighted in the body of this
document by two vertical lines.
The information provided in this Safety Data Sheet is correct to the best of our knowledge, infor-
mation and belief at the date of its publication. The information is designed only as a guidance for
safe handling, use, processing, storage, transportation, disposal and release and shall not be
considered a warranty or quality specification of any type. The information provided relates only
to the specific material identified at the top of this S DS and may not be valid when the S DS mate-
rial is used in combination with any other materials or in any process, unless specified in the t ext.
Material users should review the information and recommendations in t he specific context of their
intended manner of handling, use, processing and storage, including an assessment of the ap-
propriateness of the SDS material in the user’s end product, if applicable.
GB / EN
12 / 12
