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CONTROL AND COORDINATION
STIMULUS: any physical, chemical, or biological change
in the immediate environment of living organisms is
termed a stimulus.
Humans’ nervous system: -
  1)Central nervous system {brain, spinal cord}
  2)Peripheral nerves: {spinal-31 pairs and cranial
    nerves-12 pairs}
Sensory organs perceive or sense stimuli
Eyes- sense light -photoreceptors
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Nose- sense smell – olfactory receptor.
Ears- sense sound – phono/ auditory receptor
Skin -sense temp- thermos cutaneous /receptor
Tongue- sense taste- gustatory receptor
- Receptor cells are only present in sensory organs.
- To receive stimuli.
- Send info to the CNS.
  - 80% of what we taste is sensed by smell. Our taste
    only perceives sweet, salty, bitter, and sour. In
    case of cold, our mucus is so thick that the odor
    from the molecules isn’t able to reach the recept-
    ors. Thus, the food tastes bland.
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Info - Sensory receptors – Sensory Neuron- CNS –
Motor Neuron - effector
Neuron: -
1)basic and structural unit of the nervous system
2)Also known as nerve cell.
3)Longest cell of the body
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STRUCTURE OF NEURON
 1. Dendrites [ receives the signal from receptors]
 2. Cell body/ cyton [amplifies the electrical impulse]
   Nissl granules: aid in the production and dispersal of
chemical substances such as proteins and peptides,
 3. Axon [myelin sheath- insulating layer made of fats and proteins]
[nerve impulse travels throughout the axon until it reaches nerve
endings]
4. Nodes of Ranvier [the nodes of Ranvier allow the generation of a fast
electrical impulse along the axon. This rapid rate of conduction is called
saltatory conduction.
5.Axonal/nerve endings [ contains neurotransmitter(acetylcholine)
here electrical impulse gets changed to chemical impulse}
HOW DOES THE ELECTRICAL IMPULSE
TRAVEL THROUGH NEURON:
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Received by dendrites
Amplified by cell body
Travels through the axon to nerve endings.
Synapse: the gap between two adjacent neurons. Synapse acts like a
one-way valve because the chemical substance is present only on
one side of the gap.
  - At the synapse, the axonal terminal comes in close proximity to
    the dendron terminal of the next neuron. The Axon terminal is
    expanded to form a presynaptic knob. On the other hand, the
    dendrite terminal forms the post-synaptic depression. In
    between the two lies a narrow fluid-filled space called synaptic
    cleft. As the nerve impulses reach the presynaptic knob, the
    synaptic vesicles get stimulated to release a chemical called
    neurotransmitter in the synaptic cleft. The neurotransmitter
    diffuses in the gap to come in contact with the chemoreceptor
    sites in the post-synaptic membrane. In this way, nerve im-
    pulses pass from one synapse to stimulate the dendron of the
    other neuron.
Neuron transmitter: electrical impulse-chemical impulse -electrical
impulse
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PATHWAY :-
STIMULUS-RECEPTORS-DENDRITE OF THE SENSORY NEURON-SYNAPSE-
DENDRITES -VARIOUS NEURON- CNS -DENDRITE OF MOTOR NEURON-CELL
BODY-AXON-EFFECTOR CELLS
Three types of neurons: sensory neurons {take info from re-
ceptors to the cns}
2. motor neurons {take information from cns to effector
cells}
3. Relay neuron {coordinate between sensory and mo-
tor neurons}
NEUROMUSCULAR JUNCTION:
Neuron muscular junction: neuromuscular junction is
those synaptic junctions between neurons and the
muscle cells [motor neuron]
  - Muscles cells change the shape and arrangement
    in order to produce a respond to stimuli.
  - They have a special protein (contractile protein –
    myosin and actin) that changes the shape and ar-
    rangement and thus giving it a shorter form.
Types of actions:
Voluntarily action- those actions that we carry out by
using our brain, Consciously
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Involuntary action – that action that is performed under
the unconscious direction of the brain.
e.g., breathing, beating of heart
Reflex action- sudden, fast, and unconscious actions.
e.g., salvation, blinking of eye
Involuntary:
Set of muscular movements that don’t require thinking.
Controlled by our brain but not by our conscious think-
ing.
Stimulus isn’t usually needed.
The speed of the response is slow but for a longer dura-
tion.
It only involves smooth muscles
Controlled by medulla
Reflex Action:
Spontaneous action in response to stimulus.
Stimulus are required.
Rapid automatic response to stimulus without the con-
scious involvement of the brain. controlled by the
spinal cord.
Very fast response but for a shorter duration.
Only a message is given to the brain.
Controlled by the spinal cord
It can occur in both glands and muscles
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REFLEX ARC -
The pathway taken by nerve impulses in a reflex action
is called reflex arc. Reflex arc allows rapid response.
Most effective for quick responses.
RECEPTORS- SENSORY NEURON-SPINAL CORD- RELAY
NEURON -MOTOR NEURONS-EFFECTOR
Advantage of reflex arc: - It is important for the survival
of animals.
  - Enables the body to take quick action in harmful
    stimuli thus protecting the body.
  - Minimises the overloading of the brain.
    Reflex arc for sneezing: - pollen or dust sensed by
    receptors in the nose- sensory neurons- spinal
    cord(CNS)-relay neuron-motor neurons-
    effector(respiratory tissues)
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CNS: HUMAN BRAIN AND SPINAL CORD
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Human brain: -
Morphology: The brain is soft-whitish weighs 1.2 to 1.4
kg and occupies 98% of the total weight of the nervous
system. It has around 100 billion neurons.
1)The forebrain consists of the cerebrum, olfactory
   lobes, diencephalon
  - cerebrum {main thinking part, and voluntary ac-
     tions/largest part of the human brain. Contains two
     hemispheres connected by corpus callosum with 4
     lobes–
Cerebral hemispheres – intelligence and voluntary ac-
tions.
Olfactory lobes – Each olfactory lobe consists of an in-
terior olfactory bulb and posterior narrow olfactory
stalk. These lobes receive impulses from olfactory re-
ceptors and thus act as centers of smell.
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Temporal lobe- senses auditory reception, emotion,
hearing, memory
Frontal – controls speech, facial and muscular activity,
intellectual activity also high mental activities.
Occipital – sense color/sight, visual reception.
Parietal- sense touch/pain/temperature/taste
Diencephalon – located in the inner side of the
cerebrum. the roof is called the epi-thalamus, the sides
are called the thalami and the base is called the hypo-
thalamus. The hypothalamus has centers for hunger,
thirst, fatigue, sleep, etc. It secretes neurohor-
mones.
Motor areas – instructs muscles to do various types of
jobs.
2)Midbrain: -
- controls reflex movements of the neck, head, and
trunk in response to visual and auditory stimuli.
--Also controls the reflex movements of the eye
muscles and changes in pupil size and shape of the eye
lens.
- has 2 fibre tracts called crura cerebri and two swell-
ing on each side called superior (centres of sight re-
flexes) and inferior colliculi (auditory reflexes).
The fibrous tracts connect the hind and forebrain. All
together known as corpora quadrigemina. They per-
form the function of conduction back and forth between
the cerebrum, cerebellum, medulla, and pons.
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3) The hindbrain – the cerebellum – posture and body
balance and enable us to make precise and accurate
movements also enable us to maintain equilibrium.
 Medulla Oblongata: controlling involuntary actions
such as breathing, rate of heart, expansion, and con-
traction of blood vessels to regulate blood pressure.
Control centers for reflexes such as swallowing, cough-
ing, vomiting, etc.
Pons varolli: control breathing and sleep cycle.
   - The brain is lodged in the brain box or cranium
     which protects it. It is covered by membranes
     called meninges these are the Pia meter (in-
     nermost, thin, and vascular; arachnoid mem-
     brane ( middle thin, and vascular) and dur-
     ometer (thick, outermost, and fibrous), which
     helps to protect it.
   - The space between the membrane and the brain is
     filled with a cerebrospinal fluid which protects
     the brain from mechanical shock.
SPINAL CORD
An extension of the brain
Cylindrical
Length 37-35cm
Protected by a bony cage called the vertebral column.
It is surrounded by meninges
31 pairs of spinal nerves arise from it.
In case of a spinal cord injury, the signals coming from the receptors as well as the
signals sent to the effectors will be disrupted. As both of these signals meet in a
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bundle in the spinal cord, so, if there is any spinal cord injury then both of these sig-
nals will be disrupted.
   -   If an injury in the spinal cord will also affect the reflex arc as reflex
       arcs are controlled by the spinal cord. So, in that case, our body
       might not be able to function properly in dangerous or reflex situ-
       ations.
Hormonal system
- Exocrine: secrete their products to ducts that carry
these products to other organs or outside the body.
Example: salivary glands.
-Endocrine glands: secrete their products directly into
the bloodstream
Example: pituitary and thyroid glands.
- Hormones are chemical messengers that are secreted directly into the blood, which car-
ries them to organs and tissues of the body to exert their functions
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THYROID GLANDS: -
 - Largest endocrine glands located below the larynx
   in the front portion of the neck.
 - It secretes 3 hormones.
 - It’s a bilobed gland.
 - Secretion: - 1) thyroxine [T4]
                   2) triiodothyronine [T3][ inactive
   form of thyroxine]
                   3) thyrocalcitonin
 - T3 and T4 regulate metabolic rate, stimulate pro-
   tein synthesis, and perform the development of
   mental faculties. [ anxiety, restlessness]
 - Regulates carbohydrates, proteins, and fats meta-
   bolism in the body to provide the best balance for
   growth.
 - It also helps in regulating the body temperature.
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 -   Stimulate the rate of cellular oxidation and metabolism, maintaining basal metabolic
     rate.
 - Thyrocalcitonin: helps in reducing calcium and
   phosphate levels from blood and increases absorp-
   tion of calcium in the bone.
 -   Excess: Grave’s disease- Hypersecretion of thyroid hormones leading to loss of
     weight, rapid heartbeat, and protrusion of the eyeball.
 -   Myxoedema- deficiency of thyroid hormones in adults. This leads to a puffy appear-
     ance due to fat accumulation and low metabolic rate.
 - Iodine is necessary for the gland to make thyroxine
   hormone. In case iodine is deficient in our diet,
   there is a possibility that we might suffer from
   goiter.
 - Target organs- body tissues for cellular oxidation.
PARATHYROID GLANDS: -
 - The primary function of the four tiny parathyroid
   glands is to secrete parathyroid hormone, which
   controls the body’s calcium levels.
 - The four parathyroid glands are located on the
   thyroid’s backside.
ADRENAL GLANDS: -
 - Known as gland of emergency / suprarenal glands.
 - Two triangular-shaped glands called the adrenal
   glands are found on top of each kidney. Occurs in
   pairs.
 - Each endocrine gland has two parts: the outer ad-
   renal cortex and the inner adrenal medulla.
 - ADRENAL CORTEX: - Secrets group of steroid hor-
   mones
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   - 1) mineral corticoids [ aldosterone: maintains wa-
     ter and electrolyte balance and blood volume in
     the body]
   - 2) glucocorticoids [ cortisol: anti-inflammatory and
     anti-allergic effects]
   - 3) gonnadocorticoids [ stimulate the development
     of secondary sexual characteristics both in males
     and females]
ADRENAL MEDULLA: enables the organism to face
physical and emotional stress.
Adrenaline and noradrenaline:-
• Both the hormones together control, fear, anger, blood pressure, heartbeat,
respiration, and relaxation of smooth muscles.
    - Target organs – body muscles and smooth muscles.
    - Addison disease
Ques: -What happens in our body when a ferocious dog
chases us?
Ans: - In case of such an emergency, adrenal hormone
gets secreted which enables the body to get ready to
deal with such situations. The heart beats faster, result-
ing in a supply of more oxygen to our muscles. The
blood supply to the digestive system and skin is re-
duced due to the contraction of muscles around small
arteries in these organs. This diverts the blood to our
skeletal muscle. The breathing rate also increases be-
cause of the contractions of the diaphragm and the rib
muscles.
PITUITARY GLANDS: -
   - Located just below the hypothalamus.
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 - Smallest endocrine glands and is called “master
   gland”
 - Weighs 0.5 grams
 - Secretes growth hormones, oxytocin, anti-diuretic
   hormones, gonadotrophic hormones, LH hormones.
 - Growth hormones: deficiency – dwarfism [ stunted
   growth]
 -                       Excess - Gigantism and Ac-
   romegaly.
 - Secretes follicle-stimulating hormone/thyroid stim-
   ulating hormone/ growth hormone/ luteinizing hor-
   mone
PANCREAS: - ]
 - Functions as endo + exocrine glands. Thus, known
   as the heterocrine gland.
 - The balance of sugar and salt in our bodies is
   maintained by synthesizing pancreatic hormones.
 - As endocrine glands secrete glucagon and insulin.
 - Insulin converts glucose to glycogen. It helps in
   regulating blood sugar levels. If it is not secreted in
   proper amounts, the sugar level in the blood rises
   causing many harmful effects.
 - Glucagon is an anti-insulin hormone. Helps to regu-
   late your blood glucose levels. Glucagon increases
   your blood sugar levels and prevents it from drop-
   ping too low.
 - Disease- diabetes mellitus; patients secrete sugar
   in the urine, excessive urination, and thirst.
 THYMUS: - the lower part of the neck and upper
 parts of the chest
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  HYPOTHALAMUS: - plays an important role in the
  release of many hormones.
  - The hypothalamus produces hormones that re-
    lease or suppress other hormones across the body
    enabling them to start and stop production.
  - E.g., gonadotropin-releasing hormone (GnRH)
  - For example: when the level of growth hormone is
    low the hypothalamus secrets the growth hormone
    releasing factor to stimulate the pituitary gland to
    secrete growth hormones.
  - Located near the base of the brain, above the pitu-
    itary and below the thalamus.
  - It’s regarded as the connection between the endo-
    crine and nervous system.
  - Secretes releasing hormone and secreting hor-
    mone.
Testis and ovary: -
  - Testis secretes testosterone. Deficiency causes de-
    creased sexual drive, irritability, and depression.
  - Testosterone controls the development and func-
    tioning of accessory sex organs and secondary
    sexual characters in males.
  - Ovaries secrete estrogen and progesterone.
  - Oestrogen helps to control the development of fe-
    male secondary sexual character.
  - Progesterone helps to control uterus changes dur-
    ing menstrual cycle and helps in maintaining preg-
    nancy. Thus known as pregnancy hormone.
  - Prolactin(maternity hormone): production of milk
    oxytocin : ejection of milk
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- Deficiency:- disturbed ovulation cycle
  Innervated : supplied with nerves.
  PLANT HOROMONES
- Plant shows two different types of movement one
  dependent on growth e.g., directional growth of
  seedling is caused by growth. [ tropic movement]
- The other independent of growth- when we touch
  the leaves of the touch-me-not plant of the
  mimosa family, they begin to fold up and droop in [
  nastic movement]
- Plants also have electrical chemical means that
  carry information from cell to cell.
- In animals, some cells must change shape for
  movement to happen.
- But plant cells change shape by changing the
  amount of water in them, resulting in swelling or
  shrinking and therefore in changing shapes.
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- Responses of plants are slow / cannot be observed
  immediately/controlled by photo hormones [phyto-
  hormones].
  - Growth movements that occur in the direction of
  stimulus are known as tropic movements.
  - In this, one response acts on the protoplasm from
  one side.
  - A tropic movement may be towards or away from
  stimuli (positive and negative)
  - phototropism: plant growth response to light
  (roots are- negatively phototropic; shoot towards
  light positively phototropic)
  - geotropism: plant growth to gravity (roots – posit-
  ive; shoot – negative geotropic)
  - chemotropism: growth response to chemicals.
  (Growth of pollen tube towards the ovule); roots
  grow away from harmful acids
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    - thigmotropism: touch response. (Positive – plants
    such as peas) roots grow away from objects in the
    soil.
    - hydrotropism: response to water. (Roots are pos-
    itively hydrotropic).
Nastic movements: - seismonasty (thigmonasty) Touch
me not plant
Nyctinasty: day-night changes
Photonasty: response to stimulus light
Dandelions opens and closes in the morning and even-
ing
Thermonasty: changes in plant parts caused by temp.
and are non-directional.
Flower of tulips and crocus opens at high temp.
  - These movements are non-directional responses to
    stimuli.
  - These movements are independent of the direction
    of the stimulus.
  - These movements can be due to changes in turgor
    or growth.
  - E.g., the response of Mimosa pudica plant to touch.
  - The plant is sensitive to touch because of pad-like
    swellings called ‘pulvini’ at the base of each leaf.
  - These pulvini have a lot of water pressure which
    keeps them upright and tight.
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 - But when we touch the plant the leaves, there is a
   sudden loss of water and pressure. This causes
   leave to droop in.
PHYTOHORMONES: -
 - Growth Promotes – auxin, cytokinin, gibberellins.
 - Growth inhibitors – abscisic acid and ethylene.
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AUXIN –
  - Promote cell enlargement and cell differentiation.
  - Promotes fruit growth.
  - Auxin is synthesized and is secreted by meristem-
    atic cells at the tips of stems.
  - When a growing plant detects sunlight, a hormone
    called auxin, is synthesized at the shoot to help the
    cells to grow.
  - When light is coming from one side of the plant,
    auxin diffuses towards the shady side of the shoot.
  - This concentration of auxin stimulates the cells to
    grow longer on the side of the shoot which is away
    from the light. Thus, the plant appears to bend to-
    ward the light.
  - it induces parthenocarpy. [seedless fruits]
  - apical dominance
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Gibberellins: -
  - Promotes cell enlargement and differentiation in
    the presence of auxins.
  - They promote fruit growth.
  - Breaks seed and buds of dormancy.
  - Elongation of shoots.
  - promotes bolting, i.e. sudden elongation of internodes just before flowering in
      rosette plants like cabbage and beet.
  -   Gibberellins delays senescence.
  -   It also induces maleness in certain plants like cannabis and Cucumis.
Cytokinin:
  -   Promote root growth.
  -   Promote cell division.
  -   Helps in breaking dormancy period.
  -   Formation of chloroplast.
  -   Delay aging in leaves.
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  - Promote opening of stomata.
  - Regulates phloem transport.
  - Increase the shelf life of vegetables.
Abscisic Acid/ dormin : -
  - Functions as a growth inhibitor hormone.
  - Promotes dormancy in seeds and buds.
  - Promotes wilting and falling of leaves and fruit fall.
    [abscission of leaves}
  - Helps in stomata closing to prevent loss of h2o.
ETHYLENE: -
  - Promotes transverse growth.
  - Senescence [ biological plant death or aging]
  - Abscission of leaves and flowers
  -   Determining Flower Sex: Ethylene influences flower develop-
      ment. In some plants, it promotes the production of female flowers
      in male plants, contributing to reproductive success.
  -
  - Ripening of climatic fruits.
  - Helps in breaking dormancy of buds seeds and
    storage organs.
DORMANCY IN PLANTS: -
  - In plants, dormancy is a period of arrested plant
    growth.
  - It’s a resting, inactive metabolic condition in plants
  - For e.g., seeds are in dormant conditions before
    they get favourable conditions to break the
    dormancy and grow into a plant.
  - Occurs due to abscisic acid.
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