Give Rifampin BID for 2 days or Ceftriaxone 1
dose Indication:
- Household has a child younger than 4years
Special: who is not fully immunized
For all healthy age 12months - 40 years (if not
- >2 cases of daycare of invasive Hib within 60 - Household with a contact <18 years
received vaccine prior) if he received 2 doses
days of exposure (Vaccinate all providers and immnucompromised regardless of immunization
Haemophilus influenza of vaccine prior no need for further prophylaxis
classmate) status
Vaccine
- Within 2 weeks of
Hepatitis A exposure
LESS <12months
Clean Wound or Minor Wound
+ Vaccine in 2 different anatomical site
Immungloblin Immunocompromised
Give Vaccine
<3 doses
Chronic liver disease
Give Vaccine if last dose ≥10 years - Dirty wound: contaminated with dirt, feces,
≥3 doses soil saliva or crush or burns ...etc Allergic to vaccine
- DTaP <7 years
- ≥7 years either Tdap or Td DTaP
Dirty Wounds
Give Vaccine + IG Vaccine + HBIG within 12hr of birth and test for
<3 doses HbsAb at age 9, 18 months
Mother HBsAg Positive
Give vaccine if last dose ≥5 years HBIG Needed
≥3 doses
Vaccine at day 30, or if discharge
LESS <2kg
Newborn
Mother HBsAg Negative
*Close contact mean (>8hr and <3 feet)* vaccine at birth
- Close contact happen 7 days before Sx No need for HBIG MORE >2kg
developed or 24hr after initiating the treatment.
Vaccine + HBIG within 12hr
May involve: LESS <2kg
Rifampicin - Household, roommate, child-center
- Traveller (flight >8hr)
Meningococcal Hepatitis B Mother HBsAg Unknown Vaccine within 12hr, HBIG within 7days (if
or Ceftriaxone - Direct contact with oral secretion
mother test positive)
MORE >2kg
or Ciprofloxacin
Non-Immune: Vaccine + IG
Azithromycin for 5 days
Positive Source Immune: vaccine booster
and initate vaccination if not vaccined or did
Clarthromycin for 7 days Pertussis Any Patient
not complete vaccination
Post Exposure Non-Immune: Vaccine
Erythromycin for 14 days
Done by: Abdulaziz Alsaud
If any suggestion Email:
az.m.i.als@gmail.com
Unknown Source Immune: no need
INH for 3 months, repeat CXR and PPD after 3
months, if negative D/C
< 4 Years Give IGIM or IVIG within 6 days
Negative CXR and PPD <6 months
- Vaccine dose given prior to the 1st birthday
Follow up after 3 months and repeat CXR and do not count toward the recommended 2-
PPD - Vaccine within 72hr Vaccine within 72hr or IGIM/IVIG within 6 days
> 4 Years Measles - Immunoglobulin within 6 days (vaccine is prefer it over IGIM)
doses series of MMR
- Indication of IGIM:
6-12 months
1- Pregnant
2- immunocompromised
INH for 9 months or Alternative: TB Vaccine Alone within 72hr if the last vaccine 3- <1year
- Weekly INH + Rifapentine for 3 months of MMR >28 days
- Daily INH + Rifampin for 3 months >12months
- Daily Rifampin for 4 months Negative CXR, Postive PPD
Latent (Infection)
Treat as TB Postive CXR and PPD Prophylaxis:
- For unvaccinated immunocompetent person
Diseased Healthy and Available animal for 10 days post-exposure prophylaxis should include 4
observation, if develope Sx proceed with doses (D0, 3, 7, and 14 day)
propylaxis - For immunocompromised post-expousre
include 5 doses at (0, 3, 7, 14 and 28 days).
Neonate born (mother has chickenpox) within 5 Rapid or suspected of being rapid - If vaccinated before need only 2 doses (0,3)
days (Before delivery)- 2 days (after delivery) - RIG to be given immediately, if not available
can delay to 7 days
MORE >28 wk Neonates with a mother lack
evidence of immunity Up to 10 days VZIG
28 wk
LESS <28wk regardless of mother immunity
Pregnant women without evidence of immunity Rabies
- VZIG with 10 days
Immunocompromised without evudence of - Vaccine within 5 days Varcella
immunity
Healthy people without evidence of immnnity ≥ 12motnhs Vaccine
can be considered If VZIG or IVIG not available, at 7 days of
exposure Acylovir
