91. What is the pattern of inheritance for c. C and B only d.

D and E only
polygenic traits?
a. Autosomal dominant 96. Match List I with List II
b. X-linked recessive
c. Mendelian inheritance
d. Non-mendelian inheritance

92. With the help of the given pedigree ,find out

the probability for he birth of a child having no a. A-I, B-II, C-III, D-IV
disease and being a carrier b. A-II, B-III, C-IV, D-I
c. A-III, B-IV, C-I, D-II
d. A-IV, B-I, C-II, D-III

97. The phenomenon of pleiotrophy refers to

a. Presence of several alleles for a single gene
controlling a single crossover
a. 1/8 b. zero b. Presence of 2 alleles,each of the two genes
c. ¼ d. ½ controlling a single trait
c. A single gene affecting multiple phenotypic
93. A pink flower in snapdragon plant was crossed expression
with a red flowered Snapdragon plant. What d. When two genes affect a single character
types of phenotypes are expected in progeny?
a. Only red flowers 98. Which of the following statements are correct
b. Red as well as pink flowers regarding Klinefelter’s syndrome
c. Only pink flowers A. It was 1st described by Langdon Down
d. Red,pink as well as white flowers B. Overall muscular development. However,
feminine development is also expressed
94. Match list I with list II C. Individual is short statured
D. Physical,psychomotor and mental development
is retarded
E. Individual is sterile
a. A and B only b. C and D only
c. B and E only d. A and E only

99. Broad palm with single palm crease is visible

in a person suffering from
a. A-I, B-II, C-III, D-IV b. A-II, B-I, C-III, D-IV a. Down’s syndrome
c. A-III, B-IV, C-I, D-II d. A-I, B-II, C-IV, D-III b. Turner’s syndrome
c. Klinefelter’s syndrome
95. As per ABO blood grouping system,the blood d. Thalassemia
group of father is B+, mother is A+ and child is O+.
Their respective genotypes can be 100. which ogf the following symbols represents
A. IBi,IAi,ii B. IBIB,IAIA,ii C. IAIB,IAi,IBi mating between relatives in human pedigree
D. IAi,IBi,IAi E. IBi,IA,I,IAIB analysis?
a. A only b. B only
 (B) basic, positively charged.
(C) acidic, positively charged
(D) acidic, negatively charged

108. The process of transformation is not affected

by which of the following enzymes?
A.DNase B.RNase
C.Peptidase D.Lipase .
101. Frequency of recombination between gene (A) A, B
pairs on same chromosome as a measure of (B) A, B, C, D
distance between genes to map their positions on (C) B, C, D
chromosomes, was used for the first time by (D) A, B, C
a. TH Morgan b. Sutton and Boveri
c. Alfred Sturtevant d. Henking 109. Select the incorrect statement regarding
DNA replication.
102. XO type of sex determination can be found in (A) Leading strand is formed in 5′ → 3′ direction.
a. Birds b. Grasshoppers (B) Okazaki fragments are formed in 5′ → 3′
c. Monkeys d. Drosophila direction.
(C) DNA polymerase catalyses polymerization in 5′
103. Which one of the following occurs due to the → 3′ direction.
presence of autosome linked dominant trait? (D) DNA polymerase catalyses polymerization in
a. Haemophilia b. Thalassemia 3′ → 5′ direction
c. Sickle cell anaemia d. Myotonic dystrophy
110. The sequence of structural genes is lac
104. If a colourblind female marries a man whose operon is
mother was also colourblind,what are the (A) Lac A, Lac Y, Lac Z
chances of her progeny having colour blindness? (B) Lac A, Lac Z, Lac Y
a. 25% b. 50% (C) Lac Y, Lac Z, Lac A
c. 75% d. 100% (D) Lac Z, Lac Y, Lac A

105. The recombination frequency between the 111. Which of the following enzyme is known as
genes a & c is 5%, b and c is 15%, b & d is 9%, a & ‘chemical knife of DNA’?
b is 20%c & d is 24%, and a & d is 29%. What will (A) Ligase
be the sequence of these genes on a linear (B) Polymease
chromosomes? (C) Endonuclease
a. a, d, b, c b. d, b, a, c (D) Transcriptase
c.a, b, c, d d. a, c, b, d
112. The three codons which result in the
106. The chromosomal theory of inheritance was termination of polypeptide chain synthesis are
proposed by (A) UAA, UAG, GUA
a. Robert Brown b. TH Morgan (B) UAA, UAG, UGA
c. Sutton and Boveri d. Gregor Mendel (C) UAA, UGA, UUA
(D) UGU, UAG, UGA.
107. Histone proteins are
(A) basic, negatively charged 113. Select the incorrectly matched pair.
(A) Initiation codons - AUG 119. Enzyme ‘Taq polymerase’ used in PCR, has
(B) Stop codons - UAA, UAG, UGA been isolated from bacterium
(C) Methionine - AUG (A) Agrobacterium tumefaciesn
(D) Anticodons – mRNA (B) Thermus aquaticus
(C) Streptomyces albus
114. Which of the following pairs is incorrectly (D) Escherichia coli
matched?
(A) Purines - Adenine and Guanine 120. Which of the following bacteria is used as a
(B) Pyrimidines - Cytosine and Uracil vector for plant genetic engineering?
(C) Nucleosides - Adenosine and Thymidine (A) Agrobacterium tumefaciens
(D) DNA - Basic biomolecule (B) Bacteriophages
(C) Thermus aquaticus
115. Chemically, RNA is (i) reactive and (ii) stable (D) Pyrococcus furiosus
as compared to DNA.
(A) (i) equally, (ii) equally 121. ______________, a crown gall bacterium, is
(B) (i) less, (ii) more called as ‘natural genetic engineer’ of plants.
(C) (i) more, (ii) less (A) Escherichia coli
(D) (i) more, (ii) equally (B) Streptomyces albus
(C) Agrobacterium tumefaciens
116. In a DNA molecule, the phosphate group is (D) Azotobacter
attached to carbon ______ of the sugar residue of
its own nucleotide and carbon ______ of the 122. Which of the following tools of recombinant
sugar residue of the next nucleotide by ______ DNA technology is incorrectly paired with its use?
bonds. (A) EcoRI – Production of sticky ends
(A) 5′, 3′, phosphodiester (B) DNA ligase – Multiplication of rDNA molecules
(B) 3′, 5′, phosphodiester (C) DNA polymerase – In polymerase chain
(C) 5′, 3′, glycosidic reaction to amplify sections of DNA
(D) 3′, 5′, glycosidic (D) Selectable marker – Identification of
transformants
117. In recombinant DNA technology, the term
vector refers to 123. Which of the following are parts of
(A) the enzyme that cuts DNA into restriction biotechnology?
fragments (i) In vitro fertilization
(B) the sticky end of a DNA fragment (ii) Synthesis of a gene
(C) a plasmid used to transfer DNA into a living (iii) Correcting a defective gene
cell (iv) Developing a DNA vaccine
(D) a DNA fragment which carries only ori gene. (A) (i) and (ii)
(B) (ii) and (iii)
118. How many fragments will be generated if (C) (iii) and (iv)
you digest a linear DNA molecule with a (D) (i), (ii), (iii) and (iv)
restriction enzyme having four recognition sites
on the DNA? 124. Which one of the following is not a correct
(A) 3 (B) 6 match?
(C) 5 (D) 4 (A) Tumour inducing - Ti plasmid
(B) DNA probing - Searching for desired DNA (D) incubation of cells with recombinant DNA on
fragment ice → heat shock (42°C) → treatment with
(C) PCR - DNA staining divalent cations → placing on ice
(D) Agarose - Sea weeds
128. Read the following statements and select the
125. Which of the following statements are correct ones.
correct with respect to a bioreactor? (i) Same kind of sticky ends are produced when a
(i) It can process large volumes of culture. DNA has been cut by different restriction
(ii) It provides optimum temperature and pH. enzymes.
(iii) It is completely an automated tool (ii) Exonucleases make cuts at specific positions
(iv) It is a compact thermal cycler. within the DNA.
(A) (i) and (ii) (iii) Hin d II was the first restriction endonuclease
(B) (i), (ii) and (iii) to be isolated.
(C) (iii) and (iv) (iv) A bacteriophage has the ability to replicate
(D) (ii) and (iii) within bacterial cells by integrating its DNA with
bacterial DNA.
126. Match Column-I (enzyme) with Column-II (v) Presence of more than one recognition sites
(Characteristic/activity) and select the correct within the vector facilitates the gene cloning.
answer from codes given below (A) (i), (iii) and (v)
(B) (i) and (iv)
(C) (iii) and (iv)
(D) (ii), (iii) and (iv)

129. Smallest unit of DNA capable of

recombination.
(A) Genome
(B) Plasmid
(A) A-(iii), B-(iv), C-(i), D-(ii) (C) Recon
(B) A-(iv), B-(iii), C-(i), D-(ii) (D)Vector
(C) A-(ii), B-(i), C-(v), D-(iii)
(D) A-(iii), B-(i), C-(v), D-(ii) 130. Identify A, B, C and D in the given figure of
E.coli cloning vector pBR 322 and select the
127. The correct sequence of making a cell correct option.
competent is A B C D
(A) treatment with divalent cations → incubation (A) Hid d I Eco R I ampR ori
of cells with recombinant DNA on ice → heat (B) Hid d I Bam H I kanR ampR
shock (42°C) → placing on ice (C) Bam H I Pst I ori ampR
(B) heat shock (42°C) → incubation of cells with (D) Eco R I Bam H I ampR ori
recombinant DNA on ice → treatment with
divalent cations → placing on ice
(C) treatment with divalent cations → placing on
ice → incubation of cells with recombinant DNA
on ice → heat shock (42°C)