Principle of inheritance and variation

(NEET Pattern)

1. How many types of gametes will be produced by a trihybrid individual, where last two genes
are completely linked?
(1) Eight
(2) Four
(3) Six
(4) Two

2. Which of the following symbols are used for representing sex chromosome of birds :-
(1) ZZ – ZW
(2) XX – XY
(3) XO – XX
(4) ZZ – WW

3. A haemophilic man marries a normal homozygous woman. What is the probability that their
son will be haemophilic ?
(1) 100%
(2) 75%
(3) 25%
(4) 0%

4. If a genetic disease is transferred from a phenotypically normal but carrier female to only some
of the male progeny, the disease is:-
(1) Sickle cell Anaemia
(2) Cystic fibrosis
(3) Pseudo rickets
(4) Colour blindness

5. Which of the following disease is not related to blood of human :

(1) Haemophilia
(2) Phenylketonuria
(3) Sickle cell Anaemia
(4) Thalassemia
6. Which of the following is not a dominant trait ?
A. Colour blindness
B. Polydactyly
C. Albinism
D. DMD
(1) A, C, D
(2) A, B, C, D
(3) B, C, D
(4) A, B, C

7. In human brown eyes colour and straight hairs characters are-

(1) Dominant, Recessive
(2) Both dominant
(3) Both recessive
(4) Both are incompletely dominant

8. Given pedigree chart shows which type of inheritance.

(1) Autosomal recessive (Albinism)

(2) X–linked recessive (color blindness)
(3) Y–linked
(4) Autosomal dominant

9. Symbol used in pedigree analysis for unspecified sex is

(1)

(2)

(3)

(4)
10. Match the following columns :-

(1) A → P; B → Q; C → T; D → S; E → R
(2) A → P; B → Q; C → S; D → R; E → T
(3) A → P; B → Q; C → R; D → S; E → T
(4) A → T; B → S; C → R; D → Q; E → P

11. Given pedigree represents inheritance of myotonic dystrophy which is an autosomal dominant
disorder. What will be genotype of parents?

(1) Mother - aa Father - AA

(2) Mother – AA Father - aa
(3) Mother - Aa Father - aa
(4) Mother – aa Father - aa

12. A woman (whose father is colour blind but mother is normal) marries with haemophilic man
with hyper trichosis. What percentage of progeny will show genotypically any two of the traits
out of the three mentioned above at a given time :-
(1) 0%
(2) 25%
(3) 50%
(4) 75%

13. Pick out the correct statements :-

(a) In phenylketonuria, affected individual lacks an enzyme that converts the amino acid
phenyl alanineinto proline.
(b) Down's syndrome results in the gain of extra copy of chromosome 21.
(c) Thalassemia is an autosome autsome-linked recessive blood disease.
(d) Haemophilia is a sex linked recessive disease.
(e) Sickle cell anaemia is a quantitative problem.
(1) a, c, d
(2) b, c, d
(3) b, d, e
(4) a, b, d
14. A colour-blind man has a colour blind sister but a normal brother. The phenotype of his
parents are :-
(1) Father colour blind and mother normal
(2) Father normal and mother colour-blind
(3) Both parents are normal
(4) Both parents are colour blind

15. Part of β-chain of haemoglobin of a person suffering from sickle cell anaemia is given. The
blank circlerepresents :-

(1) same as 1
(2) same as 7
(3) same as 3
(4) same as 5

16. PKU in humans occurs due to absence of which of the following enzyme :-
(1) Homogenetesic acid oxidase
(2) Tyrosinase
(3) Phenylalanine hydroxylase
(4) More than one option is correct

17. Cystic fibrosis is an :-

(1) Autosomal dominant disorder
(2) Autosomal recessive disorder
(3) X-linked dominant disorder
(4) X-linked recessive disorder

18. If genetic disease is transferred from phenotypically normal but carries female to only some
of the maleprogeny, the disease is :-
(1) Autosomal dominant
(2) Autosomal recessive
(3) Sex-linked dominant
(4) Sex linked recessive

19. In the following pedigree, studied trait is inherited as a dominant autosomal trait. What
will be thegenotype of mother and father?

(1) Mother is aa and father is Aa

(2) Father is AA and mother is aa
(3) Father is Aa and mother Aa
(4) Both parent AA
20. Sickle cell anemia is :-
(1) Characterized by elongated sickle like RBCs with a nucleus
(2) An autosomal linked dominant trait
(3) Caused by substitution of valine by glutamic acid in the beta globin chain of
haemoglobin
(4) Caused by a change in a single base pair of DNA

21. Sickle cell anemia is :-

(1) Characterized by elongated sickle like RBCs with a nucleus
(2) An autosomal linked dominant trait
(3) Caused by substitution of valine by glutamic acid in the beta globin chain of
haemoglobin
(4) Caused by a change in a single base pair of DNA

22. Direct genetical studies are not possible in humans because :-

(1) Controlled crosses not possible in human
(2) Rate of reproduction is slow in human
(3) Longer life span of human
(4) All of these

23. The movement of a gene from one linkage group to another is called :-
(1) Crossing over
(2) Inversion
(3) Duplication
(4) Translocation

24. The leaf colour of a certain plant is controlled by one gene. For the gene, the allele G = orange
and g = green. You have a plant with orange leaves, but do not know whether the plants
genotype is GG or Gg. If you cross your unknown plant with one of the plants whose genotype
is listed below, you will be able to determine your unknown's genotype. With which plant
should you cross it ?
(1) GG (2) Gg (3) gg (4) Any genotype

25. Read the given below :

A B
Occurs in pairs Occurs in pairs
Segregate at the time of meiosis Segregate at the time of
gametesformation

Independant pair segregate One pair is always

independantly from another independent tothe another
pair pair
From this what we conclude ?
(1) A may be gene & B is chromosome pair
(2) A is single chromosome & B is allele
(3) A is chromosome pair & B is gene
(4) A & B both are surely the gene pair
26. In a Mendelian dihybrid cross, if one character shows incomplete dominance and other
character shows dominance which also shows lethality in homozygous dominant condition.
Then what will be the phenotypic ratio of progenies obtained in F2-generation?
(1) 9 : 3 : 3 : 1
(2) 3 : 1
(3) 1 : 2 : 1 : 2 : 4 : 2 : 1 : 2 : 1
(4) 2 : 4 : 2 : 1 : 2 : 1

27. Find out the sequence of genes on chromosome if recombination frequency between genes A &
B, C & D, B & C and A & C are 12%, 5%, 3% and 15% respectively.
(1) ACBD
(2) CBAD
(3) ABCD
(4) DCAB

28. If both parents are carrier for thalassaemia, which is an autosomal. Recessive disorder,
what are thechances of pregenancy resulting in an affected child?
(1) 25%
(2) 100%
(3) No chance
(4) 50%

29. Which statement is not correct ?

(a) Male individual is hemizygous for autosomal characters.
(b) 7 Mendelian characters genes are located on chromosome number 1st, 4th, 5th and 7th.
(c) In pea plant wrinkled seeds have intermediate sized starch grains.
(d) Polydactyly is an example of positive meristic change.
(e) In pea plant gene of plant height & pod colour is present on chromosome-1st.
(1) b, c, e
(2) a, c, e
(3) c, d, e
(4) a, b, c, d, e

30. What is it that forms the basis of DNA Fingerprinting?

(1) The relative amount of DNA in the ridges and grooves of the fingerprints.
(2) Satellite DNA occurring as highly repeated short DNA segments
(3) The relative proportions of purines and pyrimidines in DNA
(4) The relative difference in the DNA occurence in blood, skin and saliva

31. A plant with AaBb composition, on self pollination result in which of the following genotypic
ratio of theprogeny?
AABB AABb AaBB AaBb
(1) 2/16 2/16 2/16 2/16
(2) 1/16 2/16 2/16 4/16
(3) 1/16 2/16 2/16 1/16
(4) 1/16 1/16 1/16 1/16
32. Identify the pair that does not match :-
(1) 1 : 2 : 1 : 2 : 4 : 2 : 1 : 2 : 1 ⇒ Dihybrid genotypic ratio
(2) Inheritance of ABO Blood group ⇒ Multiple alleles
(3) One allele supress the effect of another allele ⇒ Dominance
(4) Incomplete dominance ⇒ Flower colour in Pisum sativum

33. Phenotype is due to :-

(1) Genotype only
(2) Suitable environmental condition only
(3) Both Genotype and suitable environmental condition
(4) Dominance

34. Match the following columns :-

Column A Column B
A Mendel's law I Co-dominance
B Coat colour in II Correns
cattles
C Dihybrid cross III Dominant
D Mirabilis Jalapa IV Law of independent assortmen

(1) A-IV, B-III, C-II, D-I

(2) A-III, B-I, C-IV, D-II
(3) A-I, B-II, C-III, D-IV
(4) A-III, B-I, C-II, D-IV

35. What type of allele produces its effect only in homozygous condition ?
(1) Recessive
(2) Dominant
(3) Both recessive and dominant
(4) Incomplete recessive

36. In diploid organism :-

(1) Two set of chromosome
(2) One set of chromosome
(3) 45 chromosome
(4) 23 pair chromosome
37. Match the terms in Column-I with their description in Column-II and choose the correct option :
Column - I Column - I
(a) Dominance (i) Many genes govern a single character
(b) Codominance (ii) In a heterozygous organism only one
allele expresses itself
(c) Pleiotropy (iii) In a heterozygous organism both alleles
express themselves fully
(d) Polygenic inheritance (iv) A single gene influences many characters

(a) (b) (c) (d)

(1) (ii) (i) (iv) (iii)
(2) (ii) (iii) (iv) (i)
(3) (iv) (i) (ii) (iii)
(4) (iv) (iii) (i) (ii)

38. A normal vision man whose father was colourblind, marries a normal woman whose father
was also colourblind. They have their first child as a daughter what are the chances that this
child would be carrier for colour blind ?
(1) 25%
(2) 50%
(3) 100%
(4) 0%

39. Inheritance of a trait is shown in given pedigree chart.

Find out the trait whose inheritance is probably expressed by the pedigree.
(1) Myotonic dystrophy
(2) Huntington chorea
(3) Sickle cell anaemia
(4) Colourblindness

40.

The given pedigree represents :-

(1) X-linked recessive trait
(2) Y-linked trait
(3) Autosomal recessive trait
(4) Autosomal dominant trait
41. Given below is a pedigree showing inheritance of Myotonic Dystrophy, an autosomal dominant
disorder :-

The genotypes of person 1, 2 and 3 in this family tree are :-

1 2 3
(1) MM Mm mm
(2) MM MM mm
(3) Mm MM Mm
(4) Mm Mm mm

(1) 1
(2) 2
(3) 3
(4) 4

42. Which one of the following feature is not related with Klinefelter’s :-
(1) 44 + XXY genotype
(2) 45 + XO genotype
(3) 44 + XXXY genotype
(4) Both 1 and 3

43. A test cross is performed to know :-

(1) Genotype of F2 dominants
(2) Linkage between two traits
(3) Number of alleles of a gene
(4) Success of intervarietal and interspecific cross

44. Mr. Sharma is suffering from hypertrichosis and phenylketonuria. His father is heterozygous
for phenylketonuria. The probability of Sharma sperm having one recessive autosomal allele
and holandric gene is :-
1
(1) 2
1
(2) 8
1
(3) 10
1
(4) 4
45. The figure below shows :-

(1) Independent assortment of chromosome

(2) Linkage
(3) Equational division
(4) Recombination

46. Pick out the correct statement :-

(a) Haemophilia is a sex-linked recessive disease
(b) Phenylketonuria is an autosomal recessive gene disorder
(c) Sickle cell anaemia is a X-linked recessive gene disorder
(a) and (b) are correct
(1) (b) and (c) are correct
(2) (a) and (c) are correct
(3) (a), (b) and (c) are correct

47. Match the terms in Column-I with their description in Column-II and choose the correct
option :-
Column-I Column-II
Many genes govern a single
(a) Dominance (i) character
In a heterozygous organism only
(b) Codominance (ii) one allele expresses itself
In a heterozygous organism both
(c) Pleiotropy (iii) alleles express themselves fully
A single gene influences many
Polygenic
(d) (iv) characters
inheritance
 (a) (b) (c) (d)
(1) (ii) (i) (iv) (iii)
(2) (ii) (iii) (iv) (i)
(3) (iv) (i) (ii) (iii)
(4) (iv) (iii) (i) (ii)

48. Read the following four statement (A - D)

(A) Flower colour in mirabilis follows law of segregation
(B) Punnet square is a graphical representation to know the type of gametes formed by a plant
(C) Multiple alleles are present at different locus on homologous chromosome
(D) In test cross, recessive parent is used to know the genotype of dominant individual
How many of the above statement are wrong?
(1) Four
(2) Three
(3) Two
(4) One

49. Correctly match the column U with column II :-

Column I Column II
I Dominance (A) Flower colour in snapdragon
II Incomplete dominance (B) 'AB' blood group
III Co-dominance (C) Coat colour in mice
IV Lethal gene (D) Seed shape in garden pea

(1) I-A, II-D, III-B, IV-C

(2) I-D, II-A, III-B, IV-C
(3) I-D, II-A, III-C, IV-B
(4) I-C, II-A, III-B, IV-D

50. Which of the following is not correctly described :-

(1) Linkage Physical association of genes present on a same
chromosome
(2) Pedigree It is an analysis of traits in a several of generations of a
analysis family
(3) Multiple alleles More than two character is controlled by a same allele
An organism showing a dominant phenotype is crossed
(4) Test cross with the recessiveparent.
 Answer Key

Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Ans. 2 1 4 4 2 1 1 2 2 4 3 3 2 1 1

Que. 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Ans. 1 2 4 1 4 4 4 4 3 1 4 3 1 2 2
Que. 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Ans. 2 4 3 2 1 1 2 2 4 3 4 2 1 1 1

Que. 46 47 48 49 50
Ans. 1 2 3 2 3
 Principle Inheritance and Variation
NEET PYQs

1. Phenotype of an organism is the result of –

(1) Mutations and linkages
(2) Cytoplasmic effects and nutrition
(3) Environmental changes and sexual dimorphism
(4) Genotype and environment interactions
[AIPMT 2006 (+4 /–1)]

2. How many different kinds of gametes will be produced by a plant having the genotype
AABbCC?
(1) Three
(2) Four
(3) Nine
(4) Two
[AIPMT 2006 (+4 /–1)]
3. Test cross involves –
(1) Crossing between two genotypes with recessive trait
(2) Crossing between two F1 hybrids
(3) Crossing the F1 hybrid with a double recessive genotype
(4) Crossing between two genotypes with dominant trait
[AIPMT 2006 (+4 /–1)]

4. In Mendel's experiments with garden pea, round seed shape (RR) was dominant over wrinkled
seeds (rr), yellow cotyledon (YY) was dominant over green cotyledon (yy). What are the
expected phenotypes in the F2 generation of the cross RRYY × rryy?
(1) Only round seeds with green cotyledons
(2) Only wrinkled seeds with yellow cotyledons
(3) Only wrinkled seeds with green cotyledons
(4) Round seeds with yellow cotyledons, and wrinkled seeds with yellow cotyledons
[AIPMT 2006 (+4 /–1)]

5. Which one of the following is the most suitable medium for culture of Drosophila
melanogaster?
(1) Moist bread
(2) Agar-agar
(3) Ripe banana
(4) cow dung
[AIPMT 2006 (+4 /–1)]
6. If a colourblind woman marries a normal visioned man, their sons will be :–
(1) All normal visioned
(2) One–half colourblind and one–half normal
(3) Three–fourths colourblind and one– fourth normal
(4) All colourblind
[AIPMT 2006 (+4 /–1)]
7. In which mode of inheritance do you expect more maternal influence among the offspring?
(1) Autosomal
(2) Cytoplasmic
(3) Y-linked
(4) X-linked
[AIPMT 2006 (+4 /–1)]
8. A human male produces sperms with the genotypes AB, Ab, aB, and ab, in equal proportions.
What is the corresponding genotype of this person :-
(1) AaBb
(2) AaBB
(3) AABb
(4) AABB
[AIPMT 2007 (+4 /–1)]
9. In pea plants, yellow seeds are dominant to green. If a heterozygous yellow seeded plant is
crossed with a green seeded plant, what ratio of yellow and green seeded plants would you
expect in F1 generation :-
(1) 50 : 50
(2) 9 : 1
(3) 1 : 3
(4) 3 : 1
[AIPMT 2007 (+4 /–1)]

10. Inheritance of skin colour in humans is an example of :-

(1) chromosomal aberration
(2) point mutation
(3) polygenic inheritance
(4) codominance
[AIPMT 2007 (+4 /–1)]
11. Two genes R and Y are located very close on the chromosomal linkage map of maize plant. When
RRYY and rryy genotypes are hybridized, the F2 segregation will show :-
(1) Higher number of the recombinant types.
(2) Segregation in the expected 9:3:3:1 ratio.
(3) Segregation in 3:1 ratio.
(4) Higher number of the parental types
[AIPMT 2007 (+4 /–1)]
12. Sickle cell anaemia is:-
(1) Characterized by elongated sickle like RBCs with a nucleus
(2) An autosomal linked dominant trait
(3) Caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin
(4) Caused by a change in a single base pair of DNA
[AIPMT 2009 (+4 /–1)]
13. The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC,
because "O" in it refers to having :-
(1) No antigens A and B on RBCs
(2) Other antigens besides A and B on RBCs
(3) Overdominance of this type on the genes for A and B types
(4) One antibody only - either anti–A or anti–B on the RBCs
[AIPMT 2009 (+4 /–1)]

14. Select the incorrect statement from the following :-

(1) Baldness is a sex-limited trait
(2) Linkage is an exception to the principle of independent assortment in heredity
(3) Galactosemia is an inborn error of metabolism
(4) Small population size results in random genetic drift in a population
[AIPMT 2009 (+4 /–1)]

15. Study the pedigree chart given below :-

What does it show?

(1) Inheritance of a recessive sex-linked disease like haemophilia
(2) Inheritance of a sex-lined inborn error of metabolism like phenylketonuria
(3) Inheritance of a condition like phenylketonuria as an autosomal recessive trait
(4) The pedigree chart is wrong as this is not possible
[AIPMT 2009 (+4 /–1)]

16. The genotype of a plant showing the dominant phenotype and can be detemined by :-
(1) Pedigree analysis
(2) Back cross
(3) Test cross
(4) Dihybrid cross
[AIPMT 2010 (+4 /–1)]

17. Which one of the following cannot be explained on the basis of Mendel's Law of Dominance?
(1) Alleles do not show any belending and both the characters recover as such in F2 generation
(2) Factors occur in pairs
(3) The discrete unit controlling a particular character is called a factor
(4) Out of one pair of factors one is dominant and the other recessive
[AIPMT 2010 (+4 /–1)]
18. ABO blood groups in humans are controlled by the gene I. It has three alleles - IA, IB and i. Since
there are three different alleles, six different genotypes are possible. How many phenotypes can
occur?
(1) Four
(2) Two
(3) Three
(4) One
[AIPMT 2010 (+4 /–1)]
19. Select the correct statement from the ones gives below with respect to dihybrid cross :-
(1) Genes loosely linked on the same chromosome show similar recombination’s as the tightly
linked ones
(2) Tightly linked genes on the same chromosome show very few recombination’s
(3) Tightly linked genes on the same chromosome show higher recombination
(4) Genes far apart on the same chromosome show very few recombination’s
[AIPMT 2010 (+4 /–1)]

20. Which one of the following symbols and its representation, used in human pedigree analysis is
correct?
(1) = unaffected female
(2) = male affected
(3) = mating between relatives
(4) = unaffected male
[AIPMT 2010 (+4 /–1)]

21. When two unrelated individuals or lines are crossed, the performance of F 1 hybrid is often
superior to both its parents. This phenomenon is called :-
(1) Heterosis
(2) Transformation
(3) Splicing
(4) Metamorphosis
[AIPMT (Pre) 2011 (+4 /–1)]

22. Which one of the following conditions correctly describes the manner of determining the sex in
the given example?
(1) Homozygous sex chromosomes (ZZ) determine female sex in Birds.
(2) XO type of sex chromosomes determine male sex in grasshopper
(3) XO condition in humans as found in Turner Syndrome, determines female sex.
(4) Homozygous sex chromosomes (XX) produce male in Drosophila
[AIPMT (Pre) 2011 (+4 /–1)]
23. Test cross in plants or in Drosophila involves crossing :-
(1) Between two genotypes with dominant trait
(2) Between two genotypes with recessive trait
(3) Between two F1 hybrids
(4) The F1 hybrid with a double recessive genotype
[AIPMT (Mains) 2011 (+4 /–1)]

24. Which one of the following conditions of the zygotic cell would lead to the birth of a normal
human female child?
(1) One X and one Y chromosome
(2) Two X chromosome
(3) Only one Y chromosome
(4) Only one X chromosome
[AIPMT (Mains) 2011 (+4 /–1)]
25. F2 generation in a Mendelian cross showed that both genotypic and phenotypic ratios are same
as 1 : 2 : 1. It represents a case of :-
(1) Monohybrid cross with complete dominance
(2) Monohybrid cross with incomplete dominance
(3) Co-dominance
(4) Dihybrid cross
[AIPMT (Pre) 2012 (+4 /–1)]

26. A certain road accident patient with unknown blood group needs immediate blood transfusion.
His one doctor friend at once offers his blood. What was the blood group of the donor?
(1) Blood group O
(2) Blood group A
(3) Blood group B
(4) Blood group AB
[AIPMT (Pre) 2012 (+4 /–1)]

27. A normal visioned man whose father was colour-blind marries a woman whose father was also
colour blind. They have their first child as a daughter. What are the chances that this child would
be colour-blind?
(1) 25%
(2) 50%
(3) 100%
(4) Zero percent
[AIPMT (Pre) 2012 (+4 /–1)]
28. A test cross is carried out to :-
(1) assess the number of alleles of a gene.
(2) determine whether two species or varieties will breed successfully.
(3) determine the genotype of a plant at F2
(4) predict whether two traits are linked.
[AIPMT (Mains) 2012 (+4 /–1)]

29. Represented below is the inheritance pattern of a certain type of traits in humans. Which one of
the following conditions could be an example of this pattern?

Female Male
Mother Father

Daughter Son

(1) Haemophilia
(2) Thalassemia
(3) Phenylketonuria
(4) Sickle cell anaemia
[AIPMT (Mains) 2012 (+4 /–1)]
30. If two persons with 'AB' blood group marry and have sufficiently large number of children, these
children could be classified as 'A' blood group : 'AB' blood group 'B' blood group in 1 : 2 : 1 ratio.
Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in
'AB' blood group individuals. This is an example of :
(1) Complete dominance
(2) Codominance
(3) Incomplete dominance
(4) Partial dominance
[NEET UG 2013 (+4 /–1)]

31. Which Mendelism idea is depicted by a cross in which the F1 generation resembles both the
parents?
(1) Co-dominance
(2) Incomplete dominance
(3) Law of dominance
(4) Inheritance of one gene
[NEET UG 2013 (+4 /–1)]

32. Which of the following statements is not true of two genes that show 50% recombination
frequency?
(1) If the genes are present on the same chromosome, they undergo more than one crossovers in
every meiosis
(2) The genes may be on different chromosomes
(3) The genes are tightly linked
(4) The genes show independent assortment
[NEET UG 2013 (+4 /–1)]

33. The incorrect statement with regard to Haemophilia is :-

(1) A single protein involved in the clotting of blood is affected
(2) It is a sex-linked disease
(3) It is a recessive disease
(4) It is a dominant disease
[NEET UG 2013 (+4 /–1)]

34. If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are
the chances of pregnancy resulting in an affected child?
(1) 100%
(2) No chance
(3) 50%
(4) 25%
[NEET UG 2013 (+4 /–1)]

35. Fruit colour in squash is an example of :-

(1) Recessive epistasis
(2) Dominant epistasis
(3) Complementary genes
(4) Inhibitory genes
[AIPMT 2014 (+4 /–1)]
36. A man whose father was colour blind marries a woman who had a colour-blind mother and
normal father. What percentage of male children of this couple will be colour blind?
(1) 25%
(2) 0%
(3) 50%
(4) 75%
[AIPMT 2014 (+4 /–1)]

37. A man with blood group 'A' marries a woman with blood group 'B'. What are all the possible
blood groups of their offsprings?
(1) A,B and AB only
(2) A,B,AB and O
(3) O only
(4) A and B only
[AIPMT 2015 (+4 /–1)]

38. How many pairs of contrasting characters in pea plants were studied by Mendel in his
experiments?
(1) Six
(2) Eight
(3) Seven
(4) Five
AIPMT 2015 (+4 /–1)]
39. Multiple alleles are present :-
(1) At different loci on the same chromosome
(2) At the same locus of the chromosome
(3) On non-sister chromatids
(4) On different chromosomes
[AIPMT 2015 (+4 /–1)]
40. Alleles are :-
(1) true breeding homozygotes
(2) different molecular forms of a gene
(3) heterozygotes
(4) different phenotype
[AIPMT 2015 (+4 /–1)]

41. A colour-blind man marries a woman with normal sight who has no history of colour blindness
in her family. What is the probability of their grandson (son's son) being colour blind?
(1) 0.25
(2) 0.5
(3) 1
(4) Nil
[Re-AIPMT 2015 (+4 /–1)]
42. The term "linkage" was coined by :-
(1) W.Sutton
(2) T.H. Morgan
(3) T.Boveri
(4) G.Mendel
[Re-AIPMT 2015 (+4 /–1)]
43. A pleiotropic gene :-
(1) Controls multiple traits in an individual
(2) Is expressed only in primitive plants
(3) Is a gene evolved during Pliocene
(4) Controls a trait only in combination with another gene
[Re-AIPMT 2015 (+4 /–1)]
44. In his classic experiments on pea plants, Mendel did not use :-
(1) Flower position
(2) Seed colour
(3) Pod length
(4) Seed shape
[Re-AIPMT 2015 (+4 /–1)]
45. A gene showing codominance has :-
(1) both alleles independently expressed in the heterozygote
(2) one allele dominant on the other
(3) alleles tightly linked on the same chromosome
(4) alleles that are recessive to each other
[Re-AIPMT 2015 (+4 /–1)]
46. In the following human pedigree, the filled symbols represent the affected individuals. Identify
the type of given pedigree :-
I

II

III

IV
(1) X-linked dominant
(2) Autosomal dominant
(3) X-linked recessive
(4) Autosomal recessive
[Re-AIPMT 2015 (+4 /–1)]

47. Which of the following most appropriately describes haemophilia?

(1) Recessive gene disorder
(2) X - linked recessive gene disorder
(3) Chromosomal disorder
(4) Dominant gene disorder
[NEET-I 2016 (+4 /–1)]

48. A tall true breeding garden pea plant is crossed with a dwarf true breeding garden pea plant.
When the F1 plants were selfed the resulting genotypes were in the ratio of :-
(1) 1 : 2 : 1 :: Tall homozygous : Tall heterozygous : Dwarf
(2) 1 : 2 : 1 :: Tall heterozygous : Tall homozygous : Dwarf
(3) 3 : 1 :: Tall : Dwarf
(4) 3 : 1 :: Dwarf : Tall
[NEET-I 2016 (+4 /–1)]
49. Match the terms in Column-I with their description in Column-II and choose the correct option :
Column I Column II
(a) Dominance (i) Many genes govern a single
character
(b) Codominance (ii) In a heterozygous organism only
one allele expresses itself
(c) Pleiotropy (iii) In a heterozygous organism both
alleles express themselves fully
(d) Polygenic (iv) A single gene influences many
inheritance characters

(a) (b) (c) (d)

(1) (ii) (i) (iv) (iii)
(2) (ii) (iii) (iv) (i)
(3) (iv) (i) (ii) (iii)
(4) (iv) (iii) (i) (ii)
[NEET-I 2016 (+4 /–1)]
50. Pick out the correct statements :-
(a) Haemophilia is a sex-linked recessive disease
(b) Down's syndrome is due to aneuploidy
(c) Phenylketonuria is an autosomal recessive gene disorder.
(d) Sickle cell anaemia is a X-linked recessive gene disorder
(1) (a) and (d) are correct
(2) (b) and (d) are correct
(3) (a), (c) and (d) are correct
(4) (a), (b) and (c) are correct
[NEET-I 2016 (+4 /–1)]

51. In a testcross involving F1 dihybrid flies, more parental-type offspring were produced than the
recombinant-type offspring. This indicates :-
(1) The two genes are located on two different chromosomes.
(2) Chromosomes failed to separate during meiosis.
(3) The two genes are linked and present on the same chromosome.
(4) Both of the characters are controlled by more than one gene.
[NEET-I 2016 (+4 /–1)]
52. A true breeding plant is :-
(1) Near homozygous and produces offspring of its own kind
(2) Always homozygous recessive in its genetic constitution
(3) One that is able to breed on its own
(4) Produced due to cross-pollination among unrelated plants
[NEET-II 2016 (+4 /–1)]

53. If a colour-blind man marries a woman who is homozygous for normal colour vision, the
probability of their son being colour-blind is :-
(1) 0.75
(2) 1
(3) 0
(4) 0.5
[NEET-II 2016 (+4 /–1)]
54. Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis.
Select the correct statement :-
(1) Both are due to a quantitative defect in globin chain synthesis
(2) Thalassemia is due to less synthesis of globin molecules
(3) Sickle cell anaemia is due to a quantitative problem of globin molecules
(4) Both are due to a qualitative defect in globin chain synthesis
[NEET-UG 2017 (+4 /–1)]

55. The genotypes of a husband and Wife are IAIB & IA i.

Among the blood types of their children, how many different genotypes and phenotypes are
possible?
(1) 3 genotypes; 4 phenotypes
(2) 4 genotypes; 3 phenotypes
(3) 4 genotypes; 4 phenotypes
(4) 3 genotypes; 3 phenotypes
[NEET-UG 2017 (+4 /–1)]

56. Which one from those given below is the period for Mendel's hybridization experiments?
(1) 1840 - 1850
(2) 1857 - 1869
(3) 1870 - 1877
(4) 1856 - 1863
[NEET-UG 2017 (+4 /–1)]

57. Select the correct statement :-

(1) Franklin Stahl coined the term "linkage".
(2) Punnett square was developed by a British scientist.
(3) Spliceosomes take part in translation.
(4) Transduction was discovered by S. Altman.
[NEET-UG 2018 (+4 /–1)]

58. Which of the following pairs in wrongly matched?

(1) Starch synthesis in pea: Multiple alleles
(2) ABO blood grouping: Co-dominance
(3) XO type sex determination: Grasshopper
(4) T.H. Morgan: Linkage
[NEET-UG 2018 (+4 /–1)]

59. Which of the following characteristics represent 'Inheritance of blood groups' in humans?
a. Dominance
b. Co-dominance
c. Multiple allele
d. Incomplete dominance
e. Polygenic inheritance
(1) b, c and e
(2) a, b and c
(3) b, d and e
(4) a, c and e
[NEET-UG 2018 (+4 /–1)]
60. A woman has an X-linked condition on one of her X chromosomes. This chromosome can be
inherited by :-
(1) Only daughters
(2) Only sons
(3) Only grandchildren
(4) Both sons & daughters
[NEET-UG 2018 (+4 /–1)]

61. What map unit (Centimorgan) is adopted in the construction of genetic maps?
(1) A unit of distance between two expressed genes, representing 10% cross over
(2) A unit of distance between two expressed genes, representing 100% cross over
(3) A unit of distance between genes on chromosomes, representing 1% cross over
(4) A unit of distance between genes on chromosomes, representing 50% cross over
[NEET-UG 2019 (+4 /–1)]

62. The frequency of recombination between gene pairs on the same chromosome as a measure of
the distance between genes was explained by :-
(1) T.H. Morgan
(2) Gregor J. Mendel
(3) Alfred Sturtevant
(4) Sutton Boveri
[NEET-UG 2019 (+4 /–1)]
63. In Antirrhinum (Snapdragon), a red flower was crossed with a white flower and in F1 generation,
pink flowers were obtained. When pink flowers were selfed, the F2 generation showed white,
red and pink flowers. Choose the incorrect statement from the following :-
(1) This experiment does not follow the Principle of Dominance
(2) Pink colour in F1 is due to incomplete dominance.
1 2 1
(3) Ratio of F2 is 4 (Red) : 4(Pink): 4(White)
(4) Law of Segregation does not apply in this experiment.
[NEET-UG 2019 (+4 /–1)]
64. Select the incorrect statement :-
(1) Male fruit fly is heterogametic.
(2) In male grasshoppers, 50% of sperms have no sex-chromosome.
(3) In domesticated fowls sex of progeny depends on the type of sperm rather than egg.
(4) Human males have one of their sex-chromosome much shorter than the other.
[NEET-UG 2019 (+4 /–1)]
65. Match the items of column I with column II
Column I Column II
(a) XX-XO (i) Turner's syndrome
method of sex
determination
(b) XX-XY method (ii) Female heterogametic
of sex
determination
(c) Karyotype-45 (iii) Grasshopper
(d) ZW-ZZ (iv) Female homogametic
method of sex
determination
 Select the correct option from the following :
(1) a-ii, b-iv, c-i, d-iii
(2) a-i, b-iv, c-ii, d-iii
(3) a-iii, b-iv, c-i, d-ii
(4) a-iv, b-ii, c-i, d-iii
[NEET-UG 2019 (Odisha) (+4 /–1)]

66. In a marriage between male with blood group A and female with blood group B, the progeny had
either blood group AB or B. What could be the possible genotype of parents?
(1) IAi (Male): IBIB(Female)
(2) IAIA (Male): IBIB(Female)
(3) IAIA(Male): IBi (Female)
(4) IAi (Male): IBi (Female)
[NEET-UG 2019 (Odisha) (+4 /–1)]

67. The production of gametes by the parents, the formation of zygotes, the F 1 and F2 plants, can be
understood using:-
(1) Pie diagram
(2) A pyramid diagram
(3) Punnet square
(4) Venn diagram
[NEET-UG 2019 (Odisha) (+4 /–1)]

68. Chromosomal theory of inheritance was proposed by :-

(1) Sutton and Boveri
(2) Bateson and Punnet
(3) T.H. Morgan
(4) Watson and Crick
[NEET-UG 2020 (+4 /–1)]
69. The number of contrasting characters studied by Mendel for his experiments was :-
(1) 14
(2) 4
(3) 2
(4) 7
[NEET-UG 2020 (+4 /–1)]
70. The best example for pleiotropy is :-
(1) Skin colour
(2) Phenylketoneuria
(3) Colour Blindness
(4) ABO Blood group
[NEET-UG 2020 (+4 /–1)]

71. The production of gametes by presents, formation of zygotes, the F 1 and F2 plants, can be
understood from a diagram called :-
(1) Bullet square
(2) Punch square
(3) Punnett square
(4) Net square
[NEET-UG 2021 (+4 /–1)]
72. Persons with ‘AB’ blood group are called as “Universal recipients”. This is due to :-
(1) Absence of antigens A and B on the surface of RBCs
(2) Absence of antigens A and B in plasma
(3) Presence of antibodies, anti-A and anti-B, on RBCs
(4) Absence of antibodies, anti-A and anti-B, in plasma
[NEET-UG 2021 (+4 /–1)]

73. In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what
percentage of the progeny will be diseased :-
(1) 50%
(2) 75%
(3) 25%
(4) 100%
[NEET-UG 2021 (+4 /–1)]

ANSWER KEY
Question 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Answer 4 4 3 4 3 4 2 1 1 3 4 4 1 1 3

Question 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Answer 3 1 1 2 3 1 2 4 2 2 1 4 3 1 2

Question 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45
Answer 1 3 4 4 2 3 2 3 2 2 4 2 1 3 1

Question 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Answer 4 2 1 2 4 3 1 3 2 2 4 2 1 2 4

Question 61 62 63 64 65 66 67 68 69 70 71 72 73
Answer 3 3 4 3 3 1 3 1 4 2 3 4 4