Imp Pre University
Imp Pre University
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
1. CD-95 is a marker of
(a) death receptor (b) MHC complex (c) T helper cells (d) NK cells
a. 58-year-old female met with a road accident, she had multiple fractures which were operated upon and reduced and
fixed. On 5th post operative day, she developed gram negative septicemia. A day later she went into shock.
i. What type of shock would you classify this as?
ii. Discuss in detail, pathogenesis of this shock
iii. Classify shock
iv. Discuss management and complications of shock
b. A 2-year-old male child admitted to hospital with complaints of fever, weakness and bleeding. His CBC shows [Hb =
7.5gm%, TLC = 150000/mm3, DLC: Neutrophil = 2% Lymphocyte = 3% Blast cells = 95% Platelets = 4200/mm3] blasts show
high N:C ratio, large round nuclei with scanty basophilic cytoplasm containing rod shaped granules
i. What is your probable diagnosis?
ii. Classify the condition
iii. Draw labeled diagram of peripheral smear and bone marrow findings
iv. Discuss prognosis of condition
a. Discuss pathogenesis & draw labelled diagram (Peripheral smear) of megaloblastic anaemia
b. Why P53 gene is known as Guardian of Genome?
c. What are different morphological patterns of tissue necrosis?
d. Name the different types of Antibodies which is present in patient of Systemic lupus erythematosus
e. Discuss role of Complement system in inflammation.
f. What is empathy, what is the role of empathy in patient care?
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
10. Microdeletion lead to instability of DNA, causing the cell to undergo degeneration is seen as marker in which
cancer?
(a) Colon Cancer (b) Breast cancer (c) Small cell lung (d) Melanoma
cancer
a. A 12 Years old girl was brought with complaints of fever and joint pains of 5 days duration. She had pain and
swelling of left knee and also had a history of sore throat 3 weeks ago. On examination patient have
tachycardia and apical pansystolic murmur. (2+7+7+5)
I. What is your probable diagnosis?
II. Describe the etiopathogenesis of above condition.
III. Write about the cardiac lesion and lab findings seen in this case?
IV. List the complications of this Disease.
b. A 50 years old male presents to General Surgery Outpatient with complaints of gross painless hematuria and
pain in right flank. There is also history of loss of 10 kg weight in the last 6 months. On physical examination, a
right-sided flank mass is palpable on bi-manual examination.
I. What is the probable diagnosis?
II. Discuss the clinical correlation with pathogenesis of the features.
III. How will you investigate and confirm the diagnosis?
a. CIN
b. List the causes of nephrotic syndrome with its pathophysiology.
c. Write down about pathogenesis underlying Diabetes with its complication?
d. Describe the gross and microscopic findings in patient with lobar pneumonia with likely complication.
e. Describe the contrasting features of ulcerative colitis and Crohn’s Disease.
f. How do you investigate a case of Myocardial Infarction?
a. Asbestos bodies.
b. Seminoma.
c. Carcinoid syndrome.
d. Goodpasture syndrome.
e. Enumerate four gross and microscopic findings of bronchiectasis.
f. Write four differences between typhoid ulcer and tubercular ulcer of intestine.
g. Write four differences between unconjugated and conjugated bilirubin.
h. Enumerate four liver function tests.
i. Enumerate four gross and microscopic findings of leiomyoma of uterus.
j. Enumerate four CSF findings of tubercular meningitis.
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
2. Eosinophilia occurs in
(a) Viral infections (b) Fungal infections (c) Acute pyogenic (d) Parasitic infections
infections
a. A 20-year-old girl complains of weakness, easy fatigability and breathlessness of 6 months duration. She also
complains of heavy menstrual bleeding every month. On examination, she is pale and has spoon shaped
brittle nails and cheilosis.
b. A 55year old male patient presents with progressive fatigue, weight loss and edema in legs. Laboratory tests
reveal elevated levels of protein in urine, Congo red was used to diagnose it in abdominal fat aspirates.
Deposits in spleen show sago spleen and lardaceous spleen. On physical examination, he has hepatomegaly
and macroglossia.
a. Virchow's triad
b. Paraneoplastic syndrome
c. Embolism
d. Pancytopenia
e. Enumerate giant cell
f. Difference between intravascular and extravascular hemolysis
g. Enumerate factors that influences tissue repair
h. Enumerate 4 microscopic findings of granuloma
i. Write differences between myeloblasts and lymphoblasts
j. Causes of chronic granulomatous inflammation
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
3. Which of the following is the most common primary site for bone metastasis -
(a) Prostate (b) Breast (c) Lung (d) Kidney
6. The most common primary sites for the origin of Paget's disease is -
(a) Nipple (b) Anal canal (c) Liver (d) Penis
7. Diabetes Insipidus is -
(a) Excess ADH (b) Excess cortisol (c) Decrease Cortisol (d) Decreased ACTH
a. A 68-year-old man complains of cramping abdominal pain, recent change in bowel habits and significant
weight loss. Hematological investigations show microcytic hypochromic anemia. Colonoscopy reveals a
circumferential growth in the sigmoid colon.
b. A middle-aged known smoker presented with persistent cough with expectoration and evening raise in
temperature in the last two weeks. Chest x ray identified consolidation in the lower portion of the upper lobe
of right lung. Hilar lymphadenopathy was noted. Sputum examination detected acid fast bacilli.
a. What are the common causes of anemia, and how are they classified based on their morphology and
etiology?
b. Discuss the diagnostic pathologic criteria of rheumatic heart disease.
c. How does pneumonia lead to consolidation?
d. Discuss the renal changes in diabetes mellitus.
e. Mention four important differences between Crohn disease and ulcerative colitis.
f. Enumerate the CSF findings in tuberculous meningitis.
a. Wilms Tumor.
b. What is peptic ulcer.
c. Describe bronchitis.
d. Carcinoid tumor.
e. Paraneoplastic Syndrome.
f. Write the gene involved in retinoblastoma.
g. Enlist histopathological features of Papillary of Carcinoma thyroid.
h. Mention four causes of Congenital Hyperbilirubinemia.
i. Polyps of intestine.
j. Basal cell carcinoma.
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
8. UV-radiation:
(a) Prevent formation of (b) Stimulate formation of (c) Purine dimers (d) None
pyrimidine dimers pyrimidine dimers
a. A 62-year-old woman presented with Anaemia, mild jaundice, Glossitis, Peripheral Neuropathy, anorexia and
weight loss. Her laboratory findings are: Hb 8gm/dl, TRBC count 2.4 million/cumm, MCV120fl, MCH54pg,
MCHC25g/dl.
b. A 55-year-old male patient presents with progressive fatigue, weight loss and edema in legs. Laboratory tests
reveal elevated levels of protein in urine, Congo red was used to diagnose it in abdominal fat aspirates.
Deposits in spleen show sago spleen and lardaceous spleen. On physical examination he has hepatomegaly
and macroglossia.
a. Paraneoplastic syndrome
b. Diagnostic criteria of Multiple myeloma.
c. Hemophilia
d. Role of compliments in inflammation.
e. Define hypersensitivity reaction. Write in detail about Type-I hypersensitivity reactions.
f. Blood Transfusion reactions.
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
c) Answers of Questions and Sub-questions must be written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order with black or blue pen in brackets; for example: - 1. (a) 2. (c)
f) MCQ has to be answered only once, any kind of repetition or cutting or erasing or whitener will be considered as malpractice, such answers will not be
counted in marks and action will be taken according to UFM rules of university.
g) Subjective answer should be answered in up to 30 words per marks. For example, if a question having 2 marks should answered in up to 60 marks.
3. The most common primary site for the origin of Paget's disease is:
(a) Nipple (b) Anal canal (c) Liver (d) Penis
a. A 52-year-old woman presents with a palpable lump in her right breast. On examination, the lump is hard,
irregular, and fixed to the underlying tissue. There are palpable axillary lymph nodes. A mammogram shows a
mass with micro calcifications. A biopsy is performed.
I. Based on the clinical presentation and imaging findings, what is the most likely histological diagnosis? (05
Mark)
II. What are the key prognostic factors for breast carcinoma? (05 Mark)
III. Describe the significance of immune histochemical staining in the diagnosis and prognosis of breast
carcinoma. (05 Mark)
IV. What are the histological features of Paget's disease of the breast? (05 Mark)
b. A middle-aged known smoker presented with persistent cough with expectoration and evening raise in
temperature in the past two weeks. Chest x ray identified consolidation in the lower portion of the upper lobe
of right lung. Hilar lymphadenopathy was noted. Sputum examination detected acid fast bacilli.
a. What are the common causes of anemia, and how are they classified based on their morphology and
etiology?
b. Discuss the diagnostic pathologic criteria of rheumatic heart disease
c. Enumerate the CSF findings in tuberculous meningitis
d. Describe in detail about melanoma?
e. How does hypertension lead to left ventricular hypertrophy?
f. Enlist the Classification of ovarian tumors