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Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) derived from propionic acid. It is rapidly absorbed orally with a bioavailability over 80%. It has anti-inflammatory, analgesic, and antipyretic properties. Its efficacy for rheumatoid arthritis is similar to acetylsalicylic acid but inferior to indomethacin and phenylbutazone. Common adverse reactions include gastrointestinal issues like nausea, vomiting, diarrhea and constipation. Ibuprofen is indicated for joint and extra-articular rheumatic conditions, orthopedic issues, and severe or prolonged inflammatory conditions. It is inactive for ankylosing spondylitis.

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466 views2 pages

Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) derived from propionic acid. It is rapidly absorbed orally with a bioavailability over 80%. It has anti-inflammatory, analgesic, and antipyretic properties. Its efficacy for rheumatoid arthritis is similar to acetylsalicylic acid but inferior to indomethacin and phenylbutazone. Common adverse reactions include gastrointestinal issues like nausea, vomiting, diarrhea and constipation. Ibuprofen is indicated for joint and extra-articular rheumatic conditions, orthopedic issues, and severe or prolonged inflammatory conditions. It is inactive for ankylosing spondylitis.

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Adina Irina F
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© Attribution Non-Commercial (BY-NC)
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Ibuprofen-antiinflamatoare nesteroidiene-AINS-derivat de acid propionic Farmacocinetica: Absorbtie rapida p.o., biodisponibilitate peste 80%.

Farmacodinamie-Are proprietati antiinflamatoare, analgezice, antipiretice. La bolnavii cu poliartrita reumatoida eficacitatea este asemanatoare acidului acetilsalicilic (dar inferioara indometacinei si fenilbutazonei). Farmacotoxicitate-Reactii adverse: -tulburari digestive(greata,voma,diaree,constipatie, fenomene dispeptice, epigastralgii, sangerari) apar cu o frecventa mai mica dupa acidul acetisalicilic. Farmacoterapie-Indicatii-: -afectiuni reumatice articulare si extraarticulare, afectiuni ortopedice (entorse, intinderi musculare), stari inflamatorii severe sau prelungite (ORL, stomatologie, patologie respiratorie, ginecologie etc.).Inactiv in spondilita anchilopoetica. F.epidemiologie-Contraindicatii: -ulcer in evolutie, alergie specifica sau hipersensibilitate la AINS, copii, sarcina. Farmacografie-Initial 1,2-1,8g/zi in 3prize (dupa mese).Maximum 2,4g/zi.Intretinere 0,6-1,2g/zi Produse farmaceutice care contin ibuprofen: Marcofen suspensie orala-100mg/5ml, Marcofen-400mg-cps, Marcofen100mg/5ml sirop x120ml ; Ibuprofen 600, Nurofen 200mg,400mg cps BIOFEN-Biofarm-suspensie orala-100mg/5ml; FASPIC-granule pt suspensie orala-400,600 mg; cp filmate 400mg; IBALGIN-ZENTIVA-cp filmate 200 mg, Forte-400mg; suspensie orala Baby100mg/5ml; IBUFEN-ANTIBIOTICE-cp filmate-200mg; IBUPROFEN MEDICO UNO-cps-200mg; IBUPROM-dj-200mg; IBUTOP-cps moi-400mg; IMET-Berlin Chemie-cp filmate-200mg ; LAROFEN-Laropharm-cp filmate-200mg ; PROTOPEN400-cp-400mg ; PADUDEN-cps-200mg, cps eliberare prelungita 300mg; PROFINAL-cp filmate-400,600mg; dj-200mg; REUPROFEN- Ac Helcor-cp filmate-200,400 mg; RUPAN- cp filmate-200,400 mg; SARIDON N-Bayer- cp filmate-200,400 mg; SARIXELL-Bayer- cp filmate-200,400 mg; UPFEN-Upsa-cp filmate-200mg, cp 200mg efervescente; VOLINI-Ranbaxy-cp moi-200mg.

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