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Zithromax

Zithromax (azithromycin) is a macrolide antibiotic used to treat various bacterial infections such as respiratory tract infections, skin infections, sexually transmitted diseases, and others. It works by inhibiting bacterial protein synthesis. Common dosages are 500mg initially then 250mg daily for several days depending on the infection. Special precautions are needed for patients with liver or kidney impairment, pregnancy, or children under 6 months. Common side effects include gastrointestinal issues, dizziness, and rashes. Nurses should monitor for signs of infection, obtain cultures prior to use, watch for allergic reactions, and instruct patients on proper administration.

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1K views2 pages

Zithromax

Zithromax (azithromycin) is a macrolide antibiotic used to treat various bacterial infections such as respiratory tract infections, skin infections, sexually transmitted diseases, and others. It works by inhibiting bacterial protein synthesis. Common dosages are 500mg initially then 250mg daily for several days depending on the infection. Special precautions are needed for patients with liver or kidney impairment, pregnancy, or children under 6 months. Common side effects include gastrointestinal issues, dizziness, and rashes. Nurses should monitor for signs of infection, obtain cultures prior to use, watch for allergic reactions, and instruct patients on proper administration.

Uploaded by

ianecunar
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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Brand Name: Zithromax

Generic Name: Azithromycin


Indications: Upper respiratory tract infection, including streptococcal pharyngitis, acute bacterial
exacerbations of chronic bronchitis and tonsillitis; lower respiratory tract infections,
including bronchitis and pneumonia; acute otitis media; skin ans skin structure
infections; Nongonococcal urethritis, cervbicitis, gonorrhea, and chancroid;
prevention of disseminated Myobacterium avium complex infection in patients with
advanced HIV infection; prevention of bacterial endocarditis.
Drug Classification: Agents for atypical mycobacterium, anti-infectives; macrolides
Mechanism of Action: Inhibits protein sysnthesis at the level of the 50S bacterial ribosome.
Azithromycin a macrolide antibiotic of the azalide subclass, exerts its antibacterial action
by binding to the 50s ribosomal subunits of susceptible bacteria and suppressing protein
synthesis.
Dosage: (Most respiratory and skin infections): Adults – 500 mg on 1st day, then 250 mg/day for 4
more days (total dose of 1.5 g).
Children 2-15 yr – 10 mg/kg (not >500 mg/dose) on 1 st day, then 5 mg/kg (not >250
mg/dose) for 4 more days. Pharyngitis/tonsilitis 12 mg/kg od for 5 days
Special Precautions: Sever liver impairement; severe renal impairement; pregnancy, lactation, and
children <6 mo.
Pregnancy Risk Category: B
Adverse Reactions:
CNS: dizziness, drowsiness, fatigue, headache, CV: chest pain, palpitations
GI: Pseudomembranous colitis, abdominal pain, diarrhea, nausea, cholestatic jaundice,
dyspepsia, flatulence, melena
GU: nephritis, vaginitis, Derm: photosensitivity, rashes, Endo: hyperglycemia
F and E: hyperkalemia, Misc: Angioedema
Contraindications: Hypersensitivity to azythromycin, erythromycin, or other macrolide anti-
infectives.
Forms:Tablets-250 mg, 500 mg, 600 mg; Capsules-250 mg
Nursing Responsibilities:
 Asses patient for infection (vital signs; appearance of wound, sputum, urine and
stool; WBC)
 Obtain specimens for culture and sensitivity before initiating therapy.
 Observe signs and symptoms of anaphylaxis
 Administer 1 hr before or 2 hr after meals
 Instruct client not to take azithromycin with food or antacids.

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