Scribd
Upload
1K views2 pages

Vancomycin

Vancomycin hydrochloride is an antibiotic used to treat potentially life-threatening infections caused by staphylococci, including endocarditis, meningitis, osteomyelitis, pneumonia, septicemia, and soft tissue infections. It is administered intravenously in doses of 500mg to 1g every 6 to 12 hours, up to a maximum of 4g per day. Common side effects include hypotension, nausea, vomiting, rashes, back and neck pain, eosinophilia, leukopenia, phlebitis, and hypersensitivity reactions including anaphylaxis and red man syndrome. It can cause nephrotoxicity and ototoxicity and interacts with other neph

Uploaded by

gchojn7338
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as TXT, PDF, TXT or read online on Scribd
1K views2 pages

Vancomycin

Vancomycin hydrochloride is an antibiotic used to treat potentially life-threatening infections caused by staphylococci, including endocarditis, meningitis, osteomyelitis, pneumonia, septicemia, and soft tissue infections. It is administered intravenously in doses of 500mg to 1g every 6 to 12 hours, up to a maximum of 4g per day. Common side effects include hypotension, nausea, vomiting, rashes, back and neck pain, eosinophilia, leukopenia, phlebitis, and hypersensitivity reactions including anaphylaxis and red man syndrome. It can cause nephrotoxicity and ototoxicity and interacts with other neph

Uploaded by

gchojn7338
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as TXT, PDF, TXT or read online on Scribd
You are on page 1/ 2

Generic: VANCOMYCIN HYDROCHLORIDE

Class: ABT, glycopeptide


Dose: 500mg IV q 6 hours; 1g IV q 12 hr (up to 4g/day) Duration 12-24 hr For IV
meds, compatability with IV drips and/or solutions
ADM: soln diluted to less than 5 mg/ml over @ least 60 min
monitor BP during infusion

Peak Onset end of infusion rapid


ACTION: Treatment of potentially life-threatening infections when less toxic anti-
infectives are contraindicated. Particularly useful in staphylococcal infections,
including: Endocarditis, meningitis, osteomyelitis, pneumonia septicemia, soft-
tissue infections in patients who have allergies to penicillin or its dirivatives
or when sensitivity testing demonstrates resistance to methicillin.

CONTRA: hypersensitivity,corn allergy, hearing loss,renal impairment; intestinal


obstruction or inflammation; pregnancy and lactation.

COMMON SE: hypotension, N,V, rashes, back & neck ,pain, eosinophilia, leukopenia,
phlebitis, hypersensitivity rx incl anaphylaxis, chills,fever, red-man syndrome
(with rapid infusion), superinfection
ADVERSE:
NEPHROTOXICITY leading to uremia OTOTOXICITY
ANAPHYLACTOID rx w/vascular collapse
oral hrush,genital/anal pruritis, vaginitis & vaginal discharge- REPORT
because there are resistant
INTERACTIONS: w/other drugs, OTC,herbal medicines, ototoxic & nephrotoxic drugs
(ASA, aminoglycosides, cyclosporine, cisplatin, loop diuretics);
w/neuromuscular blocking agents may cause resp depression; general anesthetics
(check aensthetic for muscular blocking agents)

TEACH; Report s/s of hypersensitivity, tinnitus, vertigo, hearing loss. If there


is not improvement in a few days. Heart pts need to be taught importance of using
ABT prophylaxis prior to dental or medical procedures. Evaluation: Check after
giving Resolution of S/S of infection. Length of time for complete resolution
depends on organism and site of infection. Endocarditis prophylaxis.
PREMEDS ASSESS: Assess pt for infection V/S; appearance of wound, sputum,urine, &
stool; CBC w/diff, WBC and beginning of and throughout therapy. Assess renal fx,
and hearing before tx, Allergy to medication monitor I/O.
RED man SYNDROME: rapid IV adm -> severe sudden & profound hypotnsion
w//wout maculopapular rash over the face, neck, upper chest &
extremieties, Rash resolves few hrs after d/c. If not-adm flds
corticosteroids, antihistamines

You might also like