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Randomized Control Trial (RCT) : Amna Inayat Medical College

Randomized control trials (RCTs) randomly assign individuals to experimental and control groups to compare the effect of an intervention. RCTs are blinded such that patients, researchers, or analysis teams may not know which group receives the intervention. RCTs eliminate known and unknown confounding biases but their results may not generalize widely since volunteers may differ from non-volunteers. RCTs also cannot be used to study exposure to harmful materials.
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0% found this document useful (0 votes)
17 views5 pages

Randomized Control Trial (RCT) : Amna Inayat Medical College

Randomized control trials (RCTs) randomly assign individuals to experimental and control groups to compare the effect of an intervention. RCTs are blinded such that patients, researchers, or analysis teams may not know which group receives the intervention. RCTs eliminate known and unknown confounding biases but their results may not generalize widely since volunteers may differ from non-volunteers. RCTs also cannot be used to study exposure to harmful materials.
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Randomized Control Trial (RCT)

By Dr Aijaz Ahmed Sohag HOD Com Medicine Dept Edit by: Abdulwasay Baloch

Amna Inayat Medical College

Randomized Control Trial- RCT


Experiment methods where individuals are randomly allocated

to an experimental or a control group The effect or intervention is compare between the two groups Two Key Features are:
1. 2.

Randomization Controlled

These trials are BLINDED Single blind means the patients do not know what the intervention is Double blind means that netither the patient nor the researcher knows what the intervention or drug is Triple blind means Analysis team also does not know which is experimental and which is control group

Plus Point of the Study

A unique strength of this study is that it eliminated both

confounding bias both known and unknown

Drawbacks of RCT
External validity refers to extent to which the results can

be generalized to a boarder community For RCT , including person is first screened, then only they are included in trial this may lead to that volunteers selected different from those who do not RCT cannot be used in instances such as exposure to harm to harmful materials such as , Toxins, Bacteria

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